HEADER CHAPERONE 22-NOV-05 2C7C
TITLE FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX
TITLE 2 (EMD-1180)
CAVEAT 2C7C ILE N 120 CBETA WRONG HAND
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: 60 KDA CHAPERONIN;
COMPND 3 CHAIN: A, B, C, D, E, F, G, H, I, J, K, L, M, N;
COMPND 4 SYNONYM: GROEL, PROTEIN CPN60, GROEL PROTEIN;
COMPND 5 ENGINEERED: YES;
COMPND 6 MOL_ID: 2;
COMPND 7 MOLECULE: 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN
COMPND 8 CPN10, GROES PROTEIN;
COMPND 9 CHAIN: O, P, Q, R, S, T, U;
COMPND 10 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 3 ORGANISM_TAXID: 562;
SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 5 EXPRESSION_SYSTEM_TAXID: 562;
SOURCE 6 MOL_ID: 2;
SOURCE 7 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 8 ORGANISM_TAXID: 562;
SOURCE 9 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 10 EXPRESSION_SYSTEM_TAXID: 562
KEYWDS ATP-BINDING, CHAPERONE, ATOMIC STRUCTURE FITTING, CELL
KEYWDS 2 CYCLE, CELL DIVISION, CHAPERONIN, NUCLEOTIDE-BINDING,
KEYWDS 3 PHOSPHORYLATION
EXPDTA ELECTRON MICROSCOPY
AUTHOR N.A.RANSON,D.K.CLARE,G.W.FARR,D.HOULDERSHAW,A.L.HORWICH,
AUTHOR 2 H.R.SAIBIL
REVDAT 5 12-JAN-10 2C7C 1 CAVEAT REMARK
REVDAT 4 24-FEB-09 2C7C 1 VERSN
REVDAT 3 20-DEC-06 2C7C 1 JRNL
REVDAT 2 02-FEB-06 2C7C 1 REMARK
REVDAT 1 25-JAN-06 2C7C 0
JRNL AUTH N.A.RANSON,D.K.CLARE,G.W.FARR,D.HOULDERSHAW,
JRNL AUTH 2 A.L.HORWICH,H.R.SAIBIL
JRNL TITL ALLOSTERIC SIGNALLING OF ATP HYDROLYSIS IN
JRNL TITL 2 GROEL-GROES COMPLEXES.
JRNL REF NAT.STRUCT.MOL.BIOL. V. 13 147 2006
JRNL REFN ISSN 1545-9993
JRNL PMID 16429154
JRNL DOI 10.1038/NSMB1046
REMARK 2
REMARK 2 RESOLUTION. 7.70 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : SPIDER, IMAGIC
REMARK 3 RECONSTRUCTION SCHEMA : PROJECTION MATCHING-BASED ANGULAR
REMARK 3 REFINEMENT OF MSA GENERATED CLASSES.
REMARK 3 ITERATIVE ALGEBRAIC RECONSTRUCTION IN
REMARK 3 SPIDER.
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : NULL
REMARK 3 REFINEMENT PROTOCOL : NULL
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : RECIPROCAL SPACE FITTING IN URO
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : 1.4
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 7.7
REMARK 3 NUMBER OF PARTICLES : 16281
REMARK 3 CTF CORRECTION METHOD : FULL CORRECTION ON 2D
REMARK 3 CLASS AVERAGES
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: RECIPROCAL SPACE FITTING OF SEVEN INDEPENDENT
REMARK 3 RIGID BODIES WITH URO. FITTED ENTITIES WERE GROEL EQUATORIAL
REMARK 3 (RESIDUES 3-136 AND 410-524), INTERMEDIATE (RESIDUES 137-192
REMARK 3 AND 374-409) AND APICAL (RESIDUES 192-373) DOMAINS, PLUS A
REMARK 3 GROES SUBUNIT. THE MAP INTO WHICH THESE COORDINATES WERE
REMARK 3 FITTED IS AVAILABLE AT THE EMD (EMD-1180)
REMARK 4
REMARK 4 2C7C COMPLIES WITH FORMAT V. 3.15, 01-DEC-08
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 05-DEC-05.
REMARK 100 THE PDBE ID CODE IS EBI-26501.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : VITREOUS ICE (CRYO EM)
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : CYCLIC
REMARK 245 NAME OF SAMPLE : GROEL-ATP7-GROES
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : 1.0
REMARK 245 SAMPLE SUPPORT DETAILS : HOLEY CARBON
REMARK 245 SAMPLE VITRIFICATION DETAILS : LIQUID ETHANE
REMARK 245 SAMPLE BUFFER : 12.5MM HEPES, 5MM KCL,
REMARK 245 5MM MGCL2
REMARK 245 PH : 7.5
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : 189
REMARK 245 TEMPERATURE (KELVIN) : 100
REMARK 245 MICROSCOPE MODEL : FEI TECNAI F20
REMARK 245 DETECTOR TYPE : KODAK SO-163 FILM
REMARK 245 MINIMUM DEFOCUS (NM) : 1100
REMARK 245 MAXIMUM DEFOCUS (NM) : 3200
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : 2.0
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : NULL
REMARK 245 ILLUMINATION MODE : LOW DOSE
REMARK 245 NOMINAL MAGNIFICATION : 50000
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : NULL
REMARK 245 ACCELERATION VOLTAGE (KV) : 200
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1
REMARK 290
REMARK 290 SYMOP SYMMETRY
REMARK 290 NNNMMM OPERATOR
REMARK 290 1555 X,Y,Z
REMARK 290
REMARK 290 WHERE NNN -> OPERATOR NUMBER
REMARK 290 MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000
REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 300 DETAILS: THE ASSEMBLY REPRESENTED IN THIS ENTRY HAS REGULAR
REMARK 300 CYCLIC POINT SYMMETRY (SCHOENFLIES SYMBOL = C21).
REMARK 350
REMARK 350 GENERATING THE BIOMOLECULE
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 SOFTWARE USED: PQS
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: 21MERIC
REMARK 350 SOFTWARE USED: PISA
REMARK 350 TOTAL BURIED SURFACE AREA: 62390 ANGSTROM**2
REMARK 350 SURFACE AREA OF THE COMPLEX: 321960 ANGSTROM**2
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -390.12 KCAL/MOL
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H, I,
REMARK 350 AND CHAINS: J, K, L, M, N, O, P, Q, R,
REMARK 350 AND CHAINS: S, T, U
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 ASN A 527
REMARK 465 ASP A 528
REMARK 465 ALA A 529
REMARK 465 ALA A 530
REMARK 465 ASP A 531
REMARK 465 LEU A 532
REMARK 465 GLY A 533
REMARK 465 ALA A 534
REMARK 465 ALA A 535
REMARK 465 GLY A 536
REMARK 465 GLY A 537
REMARK 465 MET A 538
REMARK 465 GLY A 539
REMARK 465 GLY A 540
REMARK 465 MET A 541
REMARK 465 GLY A 542
REMARK 465 GLY A 543
REMARK 465 MET A 544
REMARK 465 GLY A 545
REMARK 465 GLY A 546
REMARK 465 MET A 547
REMARK 465 MET A 548
REMARK 465 ASN B 527
REMARK 465 ASP B 528
REMARK 465 ALA B 529
REMARK 465 ALA B 530
REMARK 465 ASP B 531
REMARK 465 LEU B 532
REMARK 465 GLY B 533
REMARK 465 ALA B 534
REMARK 465 ALA B 535
REMARK 465 GLY B 536
REMARK 465 GLY B 537
REMARK 465 MET B 538
REMARK 465 GLY B 539
REMARK 465 GLY B 540
REMARK 465 MET B 541
REMARK 465 GLY B 542
REMARK 465 GLY B 543
REMARK 465 MET B 544
REMARK 465 GLY B 545
REMARK 465 GLY B 546
REMARK 465 MET B 547
REMARK 465 MET B 548
REMARK 465 ASN C 527
REMARK 465 ASP C 528
REMARK 465 ALA C 529
REMARK 465 ALA C 530
REMARK 465 ASP C 531
REMARK 465 LEU C 532
REMARK 465 GLY C 533
REMARK 465 ALA C 534
REMARK 465 ALA C 535
REMARK 465 GLY C 536
REMARK 465 GLY C 537
REMARK 465 MET C 538
REMARK 465 GLY C 539
REMARK 465 GLY C 540
REMARK 465 MET C 541
REMARK 465 GLY C 542
REMARK 465 GLY C 543
REMARK 465 MET C 544
REMARK 465 GLY C 545
REMARK 465 GLY C 546
REMARK 465 MET C 547
REMARK 465 MET C 548
REMARK 465 ASN D 527
REMARK 465 ASP D 528
REMARK 465 ALA D 529
REMARK 465 ALA D 530
REMARK 465 ASP D 531
REMARK 465 LEU D 532
REMARK 465 GLY D 533
REMARK 465 ALA D 534
REMARK 465 ALA D 535
REMARK 465 GLY D 536
REMARK 465 GLY D 537
REMARK 465 MET D 538
REMARK 465 GLY D 539
REMARK 465 GLY D 540
REMARK 465 MET D 541
REMARK 465 GLY D 542
REMARK 465 GLY D 543
REMARK 465 MET D 544
REMARK 465 GLY D 545
REMARK 465 GLY D 546
REMARK 465 MET D 547
REMARK 465 MET D 548
REMARK 465 ASN E 527
REMARK 465 ASP E 528
REMARK 465 ALA E 529
REMARK 465 ALA E 530
REMARK 465 ASP E 531
REMARK 465 LEU E 532
REMARK 465 GLY E 533
REMARK 465 ALA E 534
REMARK 465 ALA E 535
REMARK 465 GLY E 536
REMARK 465 GLY E 537
REMARK 465 MET E 538
REMARK 465 GLY E 539
REMARK 465 GLY E 540
REMARK 465 MET E 541
REMARK 465 GLY E 542
REMARK 465 GLY E 543
REMARK 465 MET E 544
REMARK 465 GLY E 545
REMARK 465 GLY E 546
REMARK 465 MET E 547
REMARK 465 MET E 548
REMARK 465 ASN F 527
REMARK 465 ASP F 528
REMARK 465 ALA F 529
REMARK 465 ALA F 530
REMARK 465 ASP F 531
REMARK 465 LEU F 532
REMARK 465 GLY F 533
REMARK 465 ALA F 534
REMARK 465 ALA F 535
REMARK 465 GLY F 536
REMARK 465 GLY F 537
REMARK 465 MET F 538
REMARK 465 GLY F 539
REMARK 465 GLY F 540
REMARK 465 MET F 541
REMARK 465 GLY F 542
REMARK 465 GLY F 543
REMARK 465 MET F 544
REMARK 465 GLY F 545
REMARK 465 GLY F 546
REMARK 465 MET F 547
REMARK 465 MET F 548
REMARK 465 ASN G 527
REMARK 465 ASP G 528
REMARK 465 ALA G 529
REMARK 465 ALA G 530
REMARK 465 ASP G 531
REMARK 465 LEU G 532
REMARK 465 GLY G 533
REMARK 465 ALA G 534
REMARK 465 ALA G 535
REMARK 465 GLY G 536
REMARK 465 GLY G 537
REMARK 465 MET G 538
REMARK 465 GLY G 539
REMARK 465 GLY G 540
REMARK 465 MET G 541
REMARK 465 GLY G 542
REMARK 465 GLY G 543
REMARK 465 MET G 544
REMARK 465 GLY G 545
REMARK 465 GLY G 546
REMARK 465 MET G 547
REMARK 465 MET G 548
REMARK 465 ALA H 2
REMARK 465 LYS H 526
REMARK 465 ASN H 527
REMARK 465 ASP H 528
REMARK 465 ALA H 529
REMARK 465 ALA H 530
REMARK 465 ASP H 531
REMARK 465 LEU H 532
REMARK 465 GLY H 533
REMARK 465 ALA H 534
REMARK 465 ALA H 535
REMARK 465 GLY H 536
REMARK 465 GLY H 537
REMARK 465 MET H 538
REMARK 465 GLY H 539
REMARK 465 GLY H 540
REMARK 465 MET H 541
REMARK 465 GLY H 542
REMARK 465 GLY H 543
REMARK 465 MET H 544
REMARK 465 GLY H 545
REMARK 465 GLY H 546
REMARK 465 MET H 547
REMARK 465 MET H 548
REMARK 465 ALA I 2
REMARK 465 LYS I 526
REMARK 465 ASN I 527
REMARK 465 ASP I 528
REMARK 465 ALA I 529
REMARK 465 ALA I 530
REMARK 465 ASP I 531
REMARK 465 LEU I 532
REMARK 465 GLY I 533
REMARK 465 ALA I 534
REMARK 465 ALA I 535
REMARK 465 GLY I 536
REMARK 465 GLY I 537
REMARK 465 MET I 538
REMARK 465 GLY I 539
REMARK 465 GLY I 540
REMARK 465 MET I 541
REMARK 465 GLY I 542
REMARK 465 GLY I 543
REMARK 465 MET I 544
REMARK 465 GLY I 545
REMARK 465 GLY I 546
REMARK 465 MET I 547
REMARK 465 MET I 548
REMARK 465 ALA J 2
REMARK 465 LYS J 526
REMARK 465 ASN J 527
REMARK 465 ASP J 528
REMARK 465 ALA J 529
REMARK 465 ALA J 530
REMARK 465 ASP J 531
REMARK 465 LEU J 532
REMARK 465 GLY J 533
REMARK 465 ALA J 534
REMARK 465 ALA J 535
REMARK 465 GLY J 536
REMARK 465 GLY J 537
REMARK 465 MET J 538
REMARK 465 GLY J 539
REMARK 465 GLY J 540
REMARK 465 MET J 541
REMARK 465 GLY J 542
REMARK 465 GLY J 543
REMARK 465 MET J 544
REMARK 465 GLY J 545
REMARK 465 GLY J 546
REMARK 465 MET J 547
REMARK 465 MET J 548
REMARK 465 ALA K 2
REMARK 465 LYS K 526
REMARK 465 ASN K 527
REMARK 465 ASP K 528
REMARK 465 ALA K 529
REMARK 465 ALA K 530
REMARK 465 ASP K 531
REMARK 465 LEU K 532
REMARK 465 GLY K 533
REMARK 465 ALA K 534
REMARK 465 ALA K 535
REMARK 465 GLY K 536
REMARK 465 GLY K 537
REMARK 465 MET K 538
REMARK 465 GLY K 539
REMARK 465 GLY K 540
REMARK 465 MET K 541
REMARK 465 GLY K 542
REMARK 465 GLY K 543
REMARK 465 MET K 544
REMARK 465 GLY K 545
REMARK 465 GLY K 546
REMARK 465 MET K 547
REMARK 465 MET K 548
REMARK 465 ALA L 2
REMARK 465 LYS L 526
REMARK 465 ASN L 527
REMARK 465 ASP L 528
REMARK 465 ALA L 529
REMARK 465 ALA L 530
REMARK 465 ASP L 531
REMARK 465 LEU L 532
REMARK 465 GLY L 533
REMARK 465 ALA L 534
REMARK 465 ALA L 535
REMARK 465 GLY L 536
REMARK 465 GLY L 537
REMARK 465 MET L 538
REMARK 465 GLY L 539
REMARK 465 GLY L 540
REMARK 465 MET L 541
REMARK 465 GLY L 542
REMARK 465 GLY L 543
REMARK 465 MET L 544
REMARK 465 GLY L 545
REMARK 465 GLY L 546
REMARK 465 MET L 547
REMARK 465 MET L 548
REMARK 465 ALA M 2
REMARK 465 LYS M 526
REMARK 465 ASN M 527
REMARK 465 ASP M 528
REMARK 465 ALA M 529
REMARK 465 ALA M 530
REMARK 465 ASP M 531
REMARK 465 LEU M 532
REMARK 465 GLY M 533
REMARK 465 ALA M 534
REMARK 465 ALA M 535
REMARK 465 GLY M 536
REMARK 465 GLY M 537
REMARK 465 MET M 538
REMARK 465 GLY M 539
REMARK 465 GLY M 540
REMARK 465 MET M 541
REMARK 465 GLY M 542
REMARK 465 GLY M 543
REMARK 465 MET M 544
REMARK 465 GLY M 545
REMARK 465 GLY M 546
REMARK 465 MET M 547
REMARK 465 MET M 548
REMARK 465 ALA N 2
REMARK 465 LYS N 526
REMARK 465 ASN N 527
REMARK 465 ASP N 528
REMARK 465 ALA N 529
REMARK 465 ALA N 530
REMARK 465 ASP N 531
REMARK 465 LEU N 532
REMARK 465 GLY N 533
REMARK 465 ALA N 534
REMARK 465 ALA N 535
REMARK 465 GLY N 536
REMARK 465 GLY N 537
REMARK 465 MET N 538
REMARK 465 GLY N 539
REMARK 465 GLY N 540
REMARK 465 MET N 541
REMARK 465 GLY N 542
REMARK 465 GLY N 543
REMARK 465 MET N 544
REMARK 465 GLY N 545
REMARK 465 GLY N 546
REMARK 465 MET N 547
REMARK 465 MET N 548
REMARK 465 MET O 1
REMARK 465 ASN O 2
REMARK 465 GLU O 96
REMARK 465 ALA O 97
REMARK 465 MET P 1
REMARK 465 ASN P 2
REMARK 465 GLU P 96
REMARK 465 ALA P 97
REMARK 465 MET Q 1
REMARK 465 ASN Q 2
REMARK 465 GLU Q 96
REMARK 465 ALA Q 97
REMARK 465 MET R 1
REMARK 465 ASN R 2
REMARK 465 GLU R 96
REMARK 465 ALA R 97
REMARK 465 MET S 1
REMARK 465 ASN S 2
REMARK 465 GLU S 96
REMARK 465 ALA S 97
REMARK 465 MET T 1
REMARK 465 ASN T 2
REMARK 465 GLU T 96
REMARK 465 ALA T 97
REMARK 465 MET U 1
REMARK 465 ASN U 2
REMARK 465 GLU U 96
REMARK 465 ALA U 97
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 ARG A 13 NH1 NH2
REMARK 470 ARG A 18 NH1 NH2
REMARK 470 ARG A 36 NH1 NH2
REMARK 470 ARG A 58 NH1 NH2
REMARK 470 ARG A 118 NH1 NH2
REMARK 470 ARG A 197 NH1 NH2
REMARK 470 TYR A 199 OH
REMARK 470 TYR A 203 OH
REMARK 470 ARG A 231 NH1 NH2
REMARK 470 ARG A 268 NH1 NH2
REMARK 470 ARG A 284 NH1 NH2
REMARK 470 ARG A 285 NH1 NH2
REMARK 470 ARG A 322 NH1 NH2
REMARK 470 ARG A 345 NH1 NH2
REMARK 470 ARG A 350 NH1 NH2
REMARK 470 TYR A 360 OH
REMARK 470 ARG A 362 NH1 NH2
REMARK 470 ARG A 368 NH1 NH2
REMARK 470 ARG A 395 NH1 NH2
REMARK 470 ARG A 404 NH1 NH2
REMARK 470 ARG A 421 NH1 NH2
REMARK 470 ARG A 430 NH1 NH2
REMARK 470 ARG A 445 NH1 NH2
REMARK 470 ARG A 452 NH1 NH2
REMARK 470 TYR A 476 OH
REMARK 470 TYR A 478 OH
REMARK 470 TYR A 485 OH
REMARK 470 ARG A 501 NH1 NH2
REMARK 470 TYR A 506 OH
REMARK 470 LYS A 526 CA C O CB CG CD CE NZ
REMARK 470 ARG B 13 NH1 NH2
REMARK 470 ARG B 18 NH1 NH2
REMARK 470 ARG B 36 NH1 NH2
REMARK 470 ARG B 58 NH1 NH2
REMARK 470 ARG B 118 NH1 NH2
REMARK 470 ARG B 197 NH1 NH2
REMARK 470 TYR B 199 OH
REMARK 470 TYR B 203 OH
REMARK 470 ARG B 231 NH1 NH2
REMARK 470 ARG B 268 NH1 NH2
REMARK 470 ARG B 284 NH1 NH2
REMARK 470 ARG B 285 NH1 NH2
REMARK 470 ARG B 322 NH1 NH2
REMARK 470 ARG B 345 NH1 NH2
REMARK 470 ARG B 350 NH1 NH2
REMARK 470 TYR B 360 OH
REMARK 470 ARG B 362 NH1 NH2
REMARK 470 ARG B 368 NH1 NH2
REMARK 470 ARG B 395 NH1 NH2
REMARK 470 ARG B 404 NH1 NH2
REMARK 470 ARG B 421 NH1 NH2
REMARK 470 ARG B 430 NH1 NH2
REMARK 470 ARG B 445 NH1 NH2
REMARK 470 ARG B 452 NH1 NH2
REMARK 470 TYR B 476 OH
REMARK 470 TYR B 478 OH
REMARK 470 TYR B 485 OH
REMARK 470 ARG B 501 NH1 NH2
REMARK 470 TYR B 506 OH
REMARK 470 LYS B 526 CA C O CB CG CD CE NZ
REMARK 470 ARG C 13 NH1 NH2
REMARK 470 ARG C 18 NH1 NH2
REMARK 470 ARG C 36 NH1 NH2
REMARK 470 ARG C 58 NH1 NH2
REMARK 470 ARG C 118 NH1 NH2
REMARK 470 ARG C 197 NH1 NH2
REMARK 470 TYR C 199 OH
REMARK 470 TYR C 203 OH
REMARK 470 ARG C 231 NH1 NH2
REMARK 470 ARG C 268 NH1 NH2
REMARK 470 ARG C 284 NH1 NH2
REMARK 470 ARG C 285 NH1 NH2
REMARK 470 ARG C 322 NH1 NH2
REMARK 470 ARG C 345 NH1 NH2
REMARK 470 ARG C 350 NH1 NH2
REMARK 470 TYR C 360 OH
REMARK 470 ARG C 362 NH1 NH2
REMARK 470 ARG C 368 NH1 NH2
REMARK 470 ARG C 395 NH1 NH2
REMARK 470 ARG C 404 NH1 NH2
REMARK 470 ARG C 421 NH1 NH2
REMARK 470 ARG C 430 NH1 NH2
REMARK 470 ARG C 445 NH1 NH2
REMARK 470 ARG C 452 NH1 NH2
REMARK 470 TYR C 476 OH
REMARK 470 TYR C 478 OH
REMARK 470 TYR C 485 OH
REMARK 470 ARG C 501 NH1 NH2
REMARK 470 TYR C 506 OH
REMARK 470 LYS C 526 CA C O CB CG CD CE NZ
REMARK 470 ARG D 13 NH1 NH2
REMARK 470 ARG D 18 NH1 NH2
REMARK 470 ARG D 36 NH1 NH2
REMARK 470 ARG D 58 NH1 NH2
REMARK 470 ARG D 118 NH1 NH2
REMARK 470 ARG D 197 NH1 NH2
REMARK 470 TYR D 199 OH
REMARK 470 TYR D 203 OH
REMARK 470 ARG D 231 NH1 NH2
REMARK 470 ARG D 268 NH1 NH2
REMARK 470 ARG D 284 NH1 NH2
REMARK 470 ARG D 285 NH1 NH2
REMARK 470 ARG D 322 NH1 NH2
REMARK 470 ARG D 345 NH1 NH2
REMARK 470 ARG D 350 NH1 NH2
REMARK 470 TYR D 360 OH
REMARK 470 ARG D 362 NH1 NH2
REMARK 470 ARG D 368 NH1 NH2
REMARK 470 ARG D 395 NH1 NH2
REMARK 470 ARG D 404 NH1 NH2
REMARK 470 ARG D 421 NH1 NH2
REMARK 470 ARG D 430 NH1 NH2
REMARK 470 ARG D 445 NH1 NH2
REMARK 470 ARG D 452 NH1 NH2
REMARK 470 TYR D 476 OH
REMARK 470 TYR D 478 OH
REMARK 470 TYR D 485 OH
REMARK 470 ARG D 501 NH1 NH2
REMARK 470 TYR D 506 OH
REMARK 470 LYS D 526 CA C O CB CG CD CE NZ
REMARK 470 ARG E 13 NH1 NH2
REMARK 470 ARG E 18 NH1 NH2
REMARK 470 ARG E 36 NH1 NH2
REMARK 470 ARG E 58 NH1 NH2
REMARK 470 ARG E 118 NH1 NH2
REMARK 470 ARG E 197 NH1 NH2
REMARK 470 TYR E 199 OH
REMARK 470 TYR E 203 OH
REMARK 470 ARG E 231 NH1 NH2
REMARK 470 ARG E 268 NH1 NH2
REMARK 470 ARG E 284 NH1 NH2
REMARK 470 ARG E 285 NH1 NH2
REMARK 470 ARG E 322 NH1 NH2
REMARK 470 ARG E 345 NH1 NH2
REMARK 470 ARG E 350 NH1 NH2
REMARK 470 TYR E 360 OH
REMARK 470 ARG E 362 NH1 NH2
REMARK 470 ARG E 368 NH1 NH2
REMARK 470 ARG E 395 NH1 NH2
REMARK 470 ARG E 404 NH1 NH2
REMARK 470 ARG E 421 NH1 NH2
REMARK 470 ARG E 430 NH1 NH2
REMARK 470 ARG E 445 NH1 NH2
REMARK 470 ARG E 452 NH1 NH2
REMARK 470 TYR E 476 OH
REMARK 470 TYR E 478 OH
REMARK 470 TYR E 485 OH
REMARK 470 ARG E 501 NH1 NH2
REMARK 470 TYR E 506 OH
REMARK 470 LYS E 526 CA C O CB CG CD CE NZ
REMARK 470 ARG F 13 NH1 NH2
REMARK 470 ARG F 18 NH1 NH2
REMARK 470 ARG F 36 NH1 NH2
REMARK 470 ARG F 58 NH1 NH2
REMARK 470 ARG F 118 NH1 NH2
REMARK 470 ARG F 197 NH1 NH2
REMARK 470 TYR F 199 OH
REMARK 470 TYR F 203 OH
REMARK 470 ARG F 231 NH1 NH2
REMARK 470 ARG F 268 NH1 NH2
REMARK 470 ARG F 284 NH1 NH2
REMARK 470 ARG F 285 NH1 NH2
REMARK 470 ARG F 322 NH1 NH2
REMARK 470 ARG F 345 NH1 NH2
REMARK 470 ARG F 350 NH1 NH2
REMARK 470 TYR F 360 OH
REMARK 470 ARG F 362 NH1 NH2
REMARK 470 ARG F 368 NH1 NH2
REMARK 470 ARG F 395 NH1 NH2
REMARK 470 ARG F 404 NH1 NH2
REMARK 470 ARG F 421 NH1 NH2
REMARK 470 ARG F 430 NH1 NH2
REMARK 470 ARG F 445 NH1 NH2
REMARK 470 ARG F 452 NH1 NH2
REMARK 470 TYR F 476 OH
REMARK 470 TYR F 478 OH
REMARK 470 TYR F 485 OH
REMARK 470 ARG F 501 NH1 NH2
REMARK 470 TYR F 506 OH
REMARK 470 LYS F 526 CA C O CB CG CD CE NZ
REMARK 470 ARG G 13 NH1 NH2
REMARK 470 ARG G 18 NH1 NH2
REMARK 470 ARG G 36 NH1 NH2
REMARK 470 ARG G 58 NH1 NH2
REMARK 470 ARG G 118 NH1 NH2
REMARK 470 ARG G 197 NH1 NH2
REMARK 470 TYR G 199 OH
REMARK 470 TYR G 203 OH
REMARK 470 ARG G 231 NH1 NH2
REMARK 470 ARG G 268 NH1 NH2
REMARK 470 ARG G 284 NH1 NH2
REMARK 470 ARG G 285 NH1 NH2
REMARK 470 ARG G 322 NH1 NH2
REMARK 470 ARG G 345 NH1 NH2
REMARK 470 ARG G 350 NH1 NH2
REMARK 470 TYR G 360 OH
REMARK 470 ARG G 362 NH1 NH2
REMARK 470 ARG G 368 NH1 NH2
REMARK 470 ARG G 395 NH1 NH2
REMARK 470 ARG G 404 NH1 NH2
REMARK 470 ARG G 421 NH1 NH2
REMARK 470 ARG G 430 NH1 NH2
REMARK 470 ARG G 445 NH1 NH2
REMARK 470 ARG G 452 NH1 NH2
REMARK 470 TYR G 476 OH
REMARK 470 TYR G 478 OH
REMARK 470 TYR G 485 OH
REMARK 470 ARG G 501 NH1 NH2
REMARK 470 TYR G 506 OH
REMARK 470 LYS G 526 CA C O CB CG CD CE NZ
REMARK 470 ARG H 13 NH1 NH2
REMARK 470 ARG H 18 NH1 NH2
REMARK 470 ARG H 36 NH1 NH2
REMARK 470 ARG H 58 NH1 NH2
REMARK 470 ARG H 118 NH1 NH2
REMARK 470 ARG H 197 NH1 NH2
REMARK 470 TYR H 199 OH
REMARK 470 TYR H 203 OH
REMARK 470 ARG H 231 NH1 NH2
REMARK 470 ARG H 268 NH1 NH2
REMARK 470 ARG H 284 NH1 NH2
REMARK 470 ARG H 285 NH1 NH2
REMARK 470 ARG H 322 NH1 NH2
REMARK 470 ARG H 345 NH1 NH2
REMARK 470 ARG H 350 NH1 NH2
REMARK 470 TYR H 360 OH
REMARK 470 ARG H 362 NH1 NH2
REMARK 470 ARG H 368 NH1 NH2
REMARK 470 ARG H 395 NH1 NH2
REMARK 470 ARG H 404 NH1 NH2
REMARK 470 ARG H 421 NH1 NH2
REMARK 470 ARG H 430 NH1 NH2
REMARK 470 ARG H 445 NH1 NH2
REMARK 470 ARG H 452 NH1 NH2
REMARK 470 TYR H 476 OH
REMARK 470 TYR H 478 OH
REMARK 470 TYR H 485 OH
REMARK 470 ARG H 501 NH1 NH2
REMARK 470 TYR H 506 OH
REMARK 470 PRO H 525 CA C O CB CG CD
REMARK 470 ARG I 13 NH1 NH2
REMARK 470 ARG I 18 NH1 NH2
REMARK 470 ARG I 36 NH1 NH2
REMARK 470 ARG I 58 NH1 NH2
REMARK 470 ARG I 118 NH1 NH2
REMARK 470 ARG I 197 NH1 NH2
REMARK 470 TYR I 199 OH
REMARK 470 TYR I 203 OH
REMARK 470 ARG I 231 NH1 NH2
REMARK 470 ARG I 268 NH1 NH2
REMARK 470 ARG I 284 NH1 NH2
REMARK 470 ARG I 285 NH1 NH2
REMARK 470 ARG I 322 NH1 NH2
REMARK 470 ARG I 345 NH1 NH2
REMARK 470 ARG I 350 NH1 NH2
REMARK 470 TYR I 360 OH
REMARK 470 ARG I 362 NH1 NH2
REMARK 470 ARG I 368 NH1 NH2
REMARK 470 ARG I 395 NH1 NH2
REMARK 470 ARG I 404 NH1 NH2
REMARK 470 ARG I 421 NH1 NH2
REMARK 470 ARG I 430 NH1 NH2
REMARK 470 ARG I 445 NH1 NH2
REMARK 470 ARG I 452 NH1 NH2
REMARK 470 TYR I 476 OH
REMARK 470 TYR I 478 OH
REMARK 470 TYR I 485 OH
REMARK 470 ARG I 501 NH1 NH2
REMARK 470 TYR I 506 OH
REMARK 470 PRO I 525 CA C O CB CG CD
REMARK 470 ARG J 13 NH1 NH2
REMARK 470 ARG J 18 NH1 NH2
REMARK 470 ARG J 36 NH1 NH2
REMARK 470 ARG J 58 NH1 NH2
REMARK 470 ARG J 118 NH1 NH2
REMARK 470 ARG J 197 NH1 NH2
REMARK 470 TYR J 199 OH
REMARK 470 TYR J 203 OH
REMARK 470 ARG J 231 NH1 NH2
REMARK 470 ARG J 268 NH1 NH2
REMARK 470 ARG J 284 NH1 NH2
REMARK 470 ARG J 285 NH1 NH2
REMARK 470 ARG J 322 NH1 NH2
REMARK 470 ARG J 345 NH1 NH2
REMARK 470 ARG J 350 NH1 NH2
REMARK 470 TYR J 360 OH
REMARK 470 ARG J 362 NH1 NH2
REMARK 470 ARG J 368 NH1 NH2
REMARK 470 ARG J 395 NH1 NH2
REMARK 470 ARG J 404 NH1 NH2
REMARK 470 ARG J 421 NH1 NH2
REMARK 470 ARG J 430 NH1 NH2
REMARK 470 ARG J 445 NH1 NH2
REMARK 470 ARG J 452 NH1 NH2
REMARK 470 TYR J 476 OH
REMARK 470 TYR J 478 OH
REMARK 470 TYR J 485 OH
REMARK 470 ARG J 501 NH1 NH2
REMARK 470 TYR J 506 OH
REMARK 470 PRO J 525 CA C O CB CG CD
REMARK 470 ARG K 13 NH1 NH2
REMARK 470 ARG K 18 NH1 NH2
REMARK 470 ARG K 36 NH1 NH2
REMARK 470 ARG K 58 NH1 NH2
REMARK 470 ARG K 118 NH1 NH2
REMARK 470 ARG K 197 NH1 NH2
REMARK 470 TYR K 199 OH
REMARK 470 TYR K 203 OH
REMARK 470 ARG K 231 NH1 NH2
REMARK 470 ARG K 268 NH1 NH2
REMARK 470 ARG K 284 NH1 NH2
REMARK 470 ARG K 285 NH1 NH2
REMARK 470 ARG K 322 NH1 NH2
REMARK 470 ARG K 345 NH1 NH2
REMARK 470 ARG K 350 NH1 NH2
REMARK 470 TYR K 360 OH
REMARK 470 ARG K 362 NH1 NH2
REMARK 470 ARG K 368 NH1 NH2
REMARK 470 ARG K 395 NH1 NH2
REMARK 470 ARG K 404 NH1 NH2
REMARK 470 ARG K 421 NH1 NH2
REMARK 470 ARG K 430 NH1 NH2
REMARK 470 ARG K 445 NH1 NH2
REMARK 470 ARG K 452 NH1 NH2
REMARK 470 TYR K 476 OH
REMARK 470 TYR K 478 OH
REMARK 470 TYR K 485 OH
REMARK 470 ARG K 501 NH1 NH2
REMARK 470 TYR K 506 OH
REMARK 470 PRO K 525 CA C O CB CG CD
REMARK 470 ARG L 13 NH1 NH2
REMARK 470 ARG L 18 NH1 NH2
REMARK 470 ARG L 36 NH1 NH2
REMARK 470 ARG L 58 NH1 NH2
REMARK 470 ARG L 118 NH1 NH2
REMARK 470 ARG L 197 NH1 NH2
REMARK 470 TYR L 199 OH
REMARK 470 TYR L 203 OH
REMARK 470 ARG L 231 NH1 NH2
REMARK 470 ARG L 268 NH1 NH2
REMARK 470 ARG L 284 NH1 NH2
REMARK 470 ARG L 285 NH1 NH2
REMARK 470 ARG L 322 NH1 NH2
REMARK 470 ARG L 345 NH1 NH2
REMARK 470 ARG L 350 NH1 NH2
REMARK 470 TYR L 360 OH
REMARK 470 ARG L 362 NH1 NH2
REMARK 470 ARG L 368 NH1 NH2
REMARK 470 ARG L 395 NH1 NH2
REMARK 470 ARG L 404 NH1 NH2
REMARK 470 ARG L 421 NH1 NH2
REMARK 470 ARG L 430 NH1 NH2
REMARK 470 ARG L 445 NH1 NH2
REMARK 470 ARG L 452 NH1 NH2
REMARK 470 TYR L 476 OH
REMARK 470 TYR L 478 OH
REMARK 470 TYR L 485 OH
REMARK 470 ARG L 501 NH1 NH2
REMARK 470 TYR L 506 OH
REMARK 470 PRO L 525 CA C O CB CG CD
REMARK 470 ARG M 13 NH1 NH2
REMARK 470 ARG M 18 NH1 NH2
REMARK 470 ARG M 36 NH1 NH2
REMARK 470 ARG M 58 NH1 NH2
REMARK 470 ARG M 118 NH1 NH2
REMARK 470 ARG M 197 NH1 NH2
REMARK 470 TYR M 199 OH
REMARK 470 TYR M 203 OH
REMARK 470 ARG M 231 NH1 NH2
REMARK 470 ARG M 268 NH1 NH2
REMARK 470 ARG M 284 NH1 NH2
REMARK 470 ARG M 285 NH1 NH2
REMARK 470 ARG M 322 NH1 NH2
REMARK 470 ARG M 345 NH1 NH2
REMARK 470 ARG M 350 NH1 NH2
REMARK 470 TYR M 360 OH
REMARK 470 ARG M 362 NH1 NH2
REMARK 470 ARG M 368 NH1 NH2
REMARK 470 ARG M 395 NH1 NH2
REMARK 470 ARG M 404 NH1 NH2
REMARK 470 ARG M 421 NH1 NH2
REMARK 470 ARG M 430 NH1 NH2
REMARK 470 ARG M 445 NH1 NH2
REMARK 470 ARG M 452 NH1 NH2
REMARK 470 TYR M 476 OH
REMARK 470 TYR M 478 OH
REMARK 470 TYR M 485 OH
REMARK 470 ARG M 501 NH1 NH2
REMARK 470 TYR M 506 OH
REMARK 470 PRO M 525 CA C O CB CG CD
REMARK 470 ARG N 13 NH1 NH2
REMARK 470 ARG N 18 NH1 NH2
REMARK 470 ARG N 36 NH1 NH2
REMARK 470 ARG N 58 NH1 NH2
REMARK 470 ARG N 118 NH1 NH2
REMARK 470 ARG N 197 NH1 NH2
REMARK 470 TYR N 199 OH
REMARK 470 TYR N 203 OH
REMARK 470 ARG N 231 NH1 NH2
REMARK 470 ARG N 268 NH1 NH2
REMARK 470 ARG N 284 NH1 NH2
REMARK 470 ARG N 285 NH1 NH2
REMARK 470 ARG N 322 NH1 NH2
REMARK 470 ARG N 345 NH1 NH2
REMARK 470 ARG N 350 NH1 NH2
REMARK 470 TYR N 360 OH
REMARK 470 ARG N 362 NH1 NH2
REMARK 470 ARG N 368 NH1 NH2
REMARK 470 ARG N 395 NH1 NH2
REMARK 470 ARG N 404 NH1 NH2
REMARK 470 ARG N 421 NH1 NH2
REMARK 470 ARG N 430 NH1 NH2
REMARK 470 ARG N 445 NH1 NH2
REMARK 470 ARG N 452 NH1 NH2
REMARK 470 TYR N 476 OH
REMARK 470 TYR N 478 OH
REMARK 470 TYR N 485 OH
REMARK 470 ARG N 501 NH1 NH2
REMARK 470 TYR N 506 OH
REMARK 470 PRO N 525 CA C O CB CG CD
REMARK 470 ARG O 4 NH1 NH2
REMARK 470 ARG O 9 NH1 NH2
REMARK 470 ARG O 14 NH1 NH2
REMARK 470 ARG O 37 NH1 NH2
REMARK 470 ARG O 47 NH1 NH2
REMARK 470 TYR O 71 OH
REMARK 470 VAL O 95 CA C O CB CG1 CG2
REMARK 470 ARG P 4 NH1 NH2
REMARK 470 ARG P 9 NH1 NH2
REMARK 470 ARG P 14 NH1 NH2
REMARK 470 ARG P 37 NH1 NH2
REMARK 470 ARG P 47 NH1 NH2
REMARK 470 TYR P 71 OH
REMARK 470 VAL P 95 CA C O CB CG1 CG2
REMARK 470 ARG Q 4 NH1 NH2
REMARK 470 ARG Q 9 NH1 NH2
REMARK 470 ARG Q 14 NH1 NH2
REMARK 470 ARG Q 37 NH1 NH2
REMARK 470 ARG Q 47 NH1 NH2
REMARK 470 TYR Q 71 OH
REMARK 470 VAL Q 95 CA C O CB CG1 CG2
REMARK 470 ARG R 4 NH1 NH2
REMARK 470 ARG R 9 NH1 NH2
REMARK 470 ARG R 14 NH1 NH2
REMARK 470 ARG R 37 NH1 NH2
REMARK 470 ARG R 47 NH1 NH2
REMARK 470 TYR R 71 OH
REMARK 470 VAL R 95 CA C O CB CG1 CG2
REMARK 470 ARG S 4 NH1 NH2
REMARK 470 ARG S 9 NH1 NH2
REMARK 470 ARG S 14 NH1 NH2
REMARK 470 ARG S 37 NH1 NH2
REMARK 470 ARG S 47 NH1 NH2
REMARK 470 TYR S 71 OH
REMARK 470 VAL S 95 CA C O CB CG1 CG2
REMARK 470 ARG T 4 NH1 NH2
REMARK 470 ARG T 9 NH1 NH2
REMARK 470 ARG T 14 NH1 NH2
REMARK 470 ARG T 37 NH1 NH2
REMARK 470 ARG T 47 NH1 NH2
REMARK 470 TYR T 71 OH
REMARK 470 VAL T 95 CA C O CB CG1 CG2
REMARK 470 ARG U 4 NH1 NH2
REMARK 470 ARG U 9 NH1 NH2
REMARK 470 ARG U 14 NH1 NH2
REMARK 470 ARG U 37 NH1 NH2
REMARK 470 ARG U 47 NH1 NH2
REMARK 470 TYR U 71 OH
REMARK 470 VAL U 95 CA C O CB CG1 CG2
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 PRO A 202 C - N - CD ANGL. DEV. = -15.5 DEGREES
REMARK 500 PRO A 218 C - N - CD ANGL. DEV. = -18.5 DEGREES
REMARK 500 PRO B 202 C - N - CD ANGL. DEV. = -16.4 DEGREES
REMARK 500 PRO B 525 C - N - CD ANGL. DEV. = -17.0 DEGREES
REMARK 500 PRO C 202 C - N - CD ANGL. DEV. = -15.0 DEGREES
REMARK 500 PRO C 525 C - N - CD ANGL. DEV. = -14.8 DEGREES
REMARK 500 PRO D 47 C - N - CD ANGL. DEV. = -17.1 DEGREES
REMARK 500 PRO D 202 C - N - CD ANGL. DEV. = -14.4 DEGREES
REMARK 500 PRO D 218 C - N - CD ANGL. DEV. = -13.7 DEGREES
REMARK 500 PRO D 279 C - N - CD ANGL. DEV. = -13.6 DEGREES
REMARK 500 PRO E 202 C - N - CD ANGL. DEV. = -14.1 DEGREES
REMARK 500 PRO E 218 C - N - CD ANGL. DEV. = -15.2 DEGREES
REMARK 500 PRO F 202 C - N - CD ANGL. DEV. = -15.4 DEGREES
REMARK 500 PRO F 525 C - N - CD ANGL. DEV. = -14.1 DEGREES
REMARK 500 PRO G 202 C - N - CD ANGL. DEV. = -15.0 DEGREES
REMARK 500 PRO G 218 C - N - CD ANGL. DEV. = -14.1 DEGREES
REMARK 500 PRO G 279 C - N - CD ANGL. DEV. = -17.7 DEGREES
REMARK 500 PRO G 525 C - N - CD ANGL. DEV. = -13.8 DEGREES
REMARK 500 PRO H 218 C - N - CD ANGL. DEV. = -14.8 DEGREES
REMARK 500 PRO I 218 C - N - CD ANGL. DEV. = -19.7 DEGREES
REMARK 500 PRO I 279 C - N - CD ANGL. DEV. = -15.1 DEGREES
REMARK 500 PRO J 218 C - N - CD ANGL. DEV. = -16.5 DEGREES
REMARK 500 PRO K 218 C - N - CD ANGL. DEV. = -18.2 DEGREES
REMARK 500 PRO K 279 C - N - CD ANGL. DEV. = -13.6 DEGREES
REMARK 500 PRO L 218 C - N - CD ANGL. DEV. = -16.5 DEGREES
REMARK 500 PRO M 47 C - N - CD ANGL. DEV. = -14.3 DEGREES
REMARK 500 PRO M 218 C - N - CD ANGL. DEV. = -14.2 DEGREES
REMARK 500 PRO M 279 C - N - CD ANGL. DEV. = -15.6 DEGREES
REMARK 500 PRO N 218 C - N - CD ANGL. DEV. = -14.6 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 ARG A 36 -155.11 -93.95
REMARK 500 ASN A 153 42.43 74.05
REMARK 500 SER A 154 18.32 80.02
REMARK 500 ARG A 197 131.81 128.00
REMARK 500 TYR A 203 13.91 -69.13
REMARK 500 ILE A 205 99.00 -59.08
REMARK 500 SER A 217 91.16 -28.90
REMARK 500 LYS A 225 162.34 176.70
REMARK 500 VAL A 271 140.52 -170.35
REMARK 500 GLU A 310 -9.48 -52.13
REMARK 500 ASN A 326 -159.76 -112.90
REMARK 500 ASP A 334 65.54 62.23
REMARK 500 GLU A 355 27.66 -145.24
REMARK 500 SER A 358 -176.95 -176.36
REMARK 500 ALA A 373 -46.41 -147.48
REMARK 500 GLU A 409 -25.11 -152.92
REMARK 500 ALA B 12 -72.15 -65.43
REMARK 500 VAL B 29 0.15 -69.99
REMARK 500 PRO B 47 160.76 -47.56
REMARK 500 ASP B 87 -144.01 -128.11
REMARK 500 ASN B 153 82.70 79.85
REMARK 500 SER B 154 -4.22 76.35
REMARK 500 TYR B 203 0.33 -69.73
REMARK 500 ILE B 205 91.37 -66.38
REMARK 500 LYS B 207 78.31 -116.43
REMARK 500 THR B 210 -33.67 -141.99
REMARK 500 SER B 217 48.31 39.65
REMARK 500 SER B 228 -37.78 -148.58
REMARK 500 GLU B 255 -164.26 -125.79
REMARK 500 PHE B 281 158.49 179.21
REMARK 500 ASN B 326 -164.39 -123.59
REMARK 500 ASP B 334 81.76 65.06
REMARK 500 GLU B 338 103.68 -53.60
REMARK 500 GLU B 355 23.57 -140.35
REMARK 500 LEU B 372 -34.19 -135.87
REMARK 500 ALA B 373 -127.27 -87.26
REMARK 500 ASN C 10 -73.67 -56.32
REMARK 500 ALA C 12 -71.28 -60.34
REMARK 500 ARG C 36 -157.94 -92.75
REMARK 500 ASP C 87 -169.43 -115.09
REMARK 500 SER C 139 20.77 -175.63
REMARK 500 ASN C 153 55.86 77.79
REMARK 500 THR C 181 -9.71 -142.23
REMARK 500 ILE C 205 85.28 -68.92
REMARK 500 SER C 228 -39.49 -151.52
REMARK 500 GLU C 255 -148.68 -135.46
REMARK 500 ASN C 326 -166.76 -115.24
REMARK 500 GLU C 363 -72.91 -57.46
REMARK 500 LYS C 364 2.93 -68.97
REMARK 500 ALA C 373 -33.33 -163.69
REMARK 500
REMARK 500 THIS ENTRY HAS 380 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 LYS A 4 ASP A 5 146.29
REMARK 500 LYS B 4 ASP B 5 147.70
REMARK 500 LYS C 4 ASP C 5 140.32
REMARK 500 LYS D 4 ASP D 5 146.56
REMARK 500 LEU D 183 GLN D 184 145.01
REMARK 500 LYS G 4 ASP G 5 148.66
REMARK 500 LYS H 4 ASP H 5 145.48
REMARK 500 PHE H 8 GLY H 9 145.47
REMARK 500 LYS J 4 ASP J 5 148.26
REMARK 500 ASP J 179 GLY J 180 -148.62
REMARK 500 GLU J 255 GLY J 256 -147.81
REMARK 500 LYS K 4 ASP K 5 147.08
REMARK 500 LYS L 4 ASP L 5 144.39
REMARK 500 VAL L 136 PRO L 137 -121.02
REMARK 500 ALA L 373 GLY L 374 136.00
REMARK 500 LYS M 4 ASP M 5 149.28
REMARK 500 GLU M 408 GLU M 409 129.88
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CHIRAL CENTERS
REMARK 500
REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL
REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY
REMARK 500 FOR AMINO ACIDS AND C1'--O4'--N1(N9)--C2' FOR
REMARK 500 NUCLEIC ACIDS OR EQUIVALENT ANGLE
REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16)
REMARK 500
REMARK 500 M RES CSSEQI IMPROPER EXPECTED FOUND DETAILS
REMARK 500 ILE N 120 -30.9 S R CBETA WRONG HAND
REMARK 500 HIS Q 7 24.4 L L OUTSIDE RANGE
REMARK 500
REMARK 500 REMARK: NULL
REMARK 700
REMARK 700 SHEET
REMARK 700 THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN
REMARK 700 ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW,
REMARK 700 TWO SHEETS ARE DEFINED.
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: 1AON RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF THE ASYMMETRIC CHAPERONIN
REMARK 900 COMPLEX GROEL/GROES/(ADP)7
REMARK 900 RELATED ID: 1DK7 RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF AN ISOLATED APICAL
REMARK 900 DOMAIN OF GROEL
REMARK 900 RELATED ID: 1DKD RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF A GROEL (APICAL DOMAIN)
REMARK 900 AND A DODECAMERIC PEPTIDE COMPLEX
REMARK 900 RELATED ID: 1EGS RELATED DB: PDB
REMARK 900 NMR STRUCTURE OF GROES MOBILE LOOP RESIDUES
REMARK 900 19 - 27 IN THE SYNTHETIC PEPTIDE (RESIDUES
REMARK 900 13 - 32) BOUND TO GROEL, 20 STRUCTURES
REMARK 900 RELATED ID: 1FY9 RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF THE HEXA-SUBSTITUTED
REMARK 900 MUTANT OF THEMOLECULAR CHAPERONIN GROEL APICAL
REMARK 900 DOMAIN
REMARK 900 RELATED ID: 1FYA RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF THE HEXA-SUBSTITUTED
REMARK 900 MUTANT OF THEMOLECULAR CHAPERONIN GROEL APICAL
REMARK 900 DOMAIN
REMARK 900 RELATED ID: 1GR5 RELATED DB: PDB
REMARK 900 SOLUTION STRUCTURE OF APO GROEL BY CRYO-
REMARK 900 ELECTRON MICROSCOPY
REMARK 900 RELATED ID: 1GR6 RELATED DB: PDB
REMARK 900 SOLUTION STRUCTURE OF GROEL(D398A)+ 250UM
REMARK 900 ATP BY CRYO-ELECTRON MICROSCOPY
REMARK 900 RELATED ID: 1GRL RELATED DB: PDB
REMARK 900 MOL_ID: 1; MOLECULE: GROEL (HSP60 CLASS);
REMARK 900 CHAIN: NULL; ENGINEERED: YES; MUTATION: R13G,
REMARK 900 A126V
REMARK 900 RELATED ID: 1GRU RELATED DB: PDB
REMARK 900 SOLUTION STRUCTURE OF GROES-ADP7-GROEL-ATP7
REMARK 900 COMPLEX BY CRYO-EM
REMARK 900 RELATED ID: 1J4Z RELATED DB: PDB
REMARK 900 STRUCTURAL AND MECHANISTIC BASIS FOR ALLOSTERY
REMARK 900 IN THEBACTERIAL CHAPERONIN GROEL; SEE REMARK
REMARK 900 400
REMARK 900 RELATED ID: 1JON RELATED DB: PDB
REMARK 900 GROEL (HSP60 CLASS) FRAGMENT COMPRISING
REMARK 900 RESIDUES 191 - 345
REMARK 900 RELATED ID: 1KID RELATED DB: PDB
REMARK 900 GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN)
REMARK 900 COMPRISING RESIDUES 191-376, MUTANT WITH ALA
REMARK 900 262 REPLACED WITH LEU AND ILE 267
REMARK 900 REPLACED WITH MET
REMARK 900 RELATED ID: 1KP8 RELATED DB: PDB
REMARK 900 STRUCTURAL BASIS FOR GROEL-ASSISTED PROTEIN
REMARK 900 FOLDING FROMTHE CRYSTAL STRUCTURE OF (GROEL-
REMARK 900 KMGATP)14 AT 2.0 ARESOLUTION
REMARK 900 RELATED ID: 1KPO RELATED DB: PDB
REMARK 900 STRUCTURAL AND MECHANISTIC BASIS FOR ALLOSTERY
REMARK 900 IN THEBACTERIAL CHAPERONIN GROEL; SEE REMARK
REMARK 900 400
REMARK 900 RELATED ID: 1LA1 RELATED DB: PDB
REMARK 900 GRO-EL FRAGMENT (APICAL DOMAIN) COMPRISING
REMARK 900 RESIDUES 188-379
REMARK 900 RELATED ID: 1MNF RELATED DB: PDB
REMARK 900 DOMAIN MOTIONS IN GROEL UPON BINDING OF AN
REMARK 900 OLIGOPEPTIDE
REMARK 900 RELATED ID: 1OEL RELATED DB: PDB
REMARK 900 MOL_ID: 1; MOLECULE: GROEL (HSP60 CLASS);
REMARK 900 CHAIN: A, B, C, D, E, F, G; ENGINEERED:
REMARK 900 YES; MUTATION: R13G, A126V
REMARK 900 RELATED ID: 1PCQ RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF GROEL-GROES
REMARK 900 RELATED ID: 1PF9 RELATED DB: PDB
REMARK 900 GROEL-GROES-ADP
REMARK 900 RELATED ID: 1SS8 RELATED DB: PDB
REMARK 900 GROEL
REMARK 900 RELATED ID: 1SVT RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF GROEL14-GROES7-(ADP-
REMARK 900 ALFX)7
REMARK 900 RELATED ID: 1SX3 RELATED DB: PDB
REMARK 900 GROEL14-(ATPGAMMAS)14
REMARK 900 RELATED ID: 1SX4 RELATED DB: PDB
REMARK 900 GROEL-GROES-ADP7
REMARK 900 RELATED ID: 1XCK RELATED DB: PDB
REMARK 900 CRYSTAL STRUCTURE OF APO GROEL
REMARK 900 RELATED ID: 2C7D RELATED DB: PDB
REMARK 900 FITTED COORDINATES FOR GROEL-ADP7-GROES CRYO
REMARK 900 -EM COMPLEX (EMD-1181)
REMARK 900 RELATED ID: 2C7E RELATED DB: PDB
REMARK 900 REVISED ATOMIC STRUCTURE FITTING INTO A
REMARK 900 GROEL(D398A)-ATP7 CRYO-EM MAP (EMD 1047)
REMARK 900 RELATED ID: EMD-1180 RELATED DB: EMDB
DBREF 2C7C A 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C B 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C C 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C D 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C E 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C F 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C G 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C H 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C I 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C J 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C K 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C L 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C M 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C N 2 548 UNP P0A6F5 CH60_ECOLI 1 547
DBREF 2C7C O 1 97 UNP P0A6F9 CH10_ECOLI 1 97
DBREF 2C7C P 1 97 UNP P0A6F9 CH10_ECOLI 1 97
DBREF 2C7C Q 1 97 UNP P0A6F9 CH10_ECOLI 1 97
DBREF 2C7C R 1 97 UNP P0A6F9 CH10_ECOLI 1 97
DBREF 2C7C S 1 97 UNP P0A6F9 CH10_ECOLI 1 97
DBREF 2C7C T 1 97 UNP P0A6F9 CH10_ECOLI 1 97
DBREF 2C7C U 1 97 UNP P0A6F9 CH10_ECOLI 1 97
SEQRES 1 A 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 A 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 A 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 A 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 A 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 A 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 A 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 A 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 A 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 A 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 A 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 A 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 A 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 A 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 A 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 A 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 A 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 A 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 A 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 A 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 A 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 A 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 A 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 A 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 A 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 A 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 A 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 A 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 A 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 A 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 A 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 A 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 A 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 A 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 A 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 A 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 A 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 A 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 A 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 A 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 A 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 A 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 A 547 MET
SEQRES 1 B 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 B 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 B 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 B 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 B 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 B 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 B 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 B 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 B 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 B 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 B 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 B 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 B 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 B 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 B 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 B 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 B 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 B 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 B 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 B 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 B 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 B 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 B 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 B 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 B 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 B 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 B 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 B 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 B 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 B 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 B 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 B 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 B 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 B 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 B 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 B 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 B 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 B 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 B 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 B 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 B 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 B 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 B 547 MET
SEQRES 1 C 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 C 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 C 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 C 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 C 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 C 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 C 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 C 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 C 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 C 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 C 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 C 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 C 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 C 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 C 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 C 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 C 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 C 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 C 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 C 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 C 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 C 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 C 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 C 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 C 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 C 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 C 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 C 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 C 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 C 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 C 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 C 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 C 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 C 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 C 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 C 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 C 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 C 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 C 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 C 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 C 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 C 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 C 547 MET
SEQRES 1 D 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 D 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 D 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 D 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 D 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 D 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 D 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 D 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 D 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 D 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 D 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 D 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 D 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 D 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 D 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 D 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 D 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 D 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 D 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 D 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 D 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 D 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 D 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 D 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 D 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 D 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 D 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 D 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 D 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 D 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 D 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 D 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 D 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 D 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 D 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 D 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 D 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 D 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 D 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 D 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 D 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 D 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 D 547 MET
SEQRES 1 E 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 E 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 E 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 E 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 E 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 E 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 E 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 E 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 E 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 E 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 E 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 E 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 E 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 E 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 E 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 E 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 E 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 E 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 E 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 E 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 E 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 E 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 E 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 E 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 E 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 E 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 E 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 E 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 E 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 E 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 E 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 E 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 E 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 E 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 E 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 E 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 E 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 E 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 E 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 E 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 E 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 E 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 E 547 MET
SEQRES 1 F 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 F 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 F 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 F 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 F 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 F 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 F 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 F 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 F 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 F 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 F 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 F 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 F 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 F 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 F 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 F 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 F 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 F 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 F 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 F 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 F 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 F 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 F 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 F 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 F 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 F 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 F 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 F 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 F 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 F 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 F 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 F 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 F 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 F 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 F 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 F 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 F 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 F 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 F 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 F 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 F 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 F 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 F 547 MET
SEQRES 1 G 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 G 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 G 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 G 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 G 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 G 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 G 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 G 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 G 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 G 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 G 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 G 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 G 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 G 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 G 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 G 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 G 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 G 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 G 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 G 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 G 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 G 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 G 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 G 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 G 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 G 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 G 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 G 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 G 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 G 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 G 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 G 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 G 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 G 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 G 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 G 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 G 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 G 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 G 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 G 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 G 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 G 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 G 547 MET
SEQRES 1 H 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 H 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 H 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 H 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 H 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 H 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 H 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 H 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 H 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 H 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 H 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 H 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 H 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 H 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 H 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 H 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 H 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 H 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 H 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 H 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 H 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 H 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 H 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 H 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 H 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 H 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 H 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 H 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 H 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 H 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 H 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 H 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 H 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 H 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 H 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 H 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 H 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 H 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 H 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 H 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 H 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 H 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 H 547 MET
SEQRES 1 I 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 I 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 I 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 I 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 I 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 I 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 I 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 I 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 I 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 I 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 I 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 I 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 I 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 I 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 I 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 I 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 I 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 I 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 I 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 I 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 I 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 I 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 I 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 I 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 I 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 I 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 I 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 I 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 I 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 I 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 I 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 I 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 I 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 I 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 I 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 I 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 I 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 I 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 I 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 I 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 I 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 I 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 I 547 MET
SEQRES 1 J 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 J 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 J 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 J 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 J 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 J 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 J 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 J 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 J 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 J 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 J 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 J 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 J 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 J 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 J 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 J 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 J 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 J 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 J 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 J 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 J 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 J 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 J 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 J 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 J 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 J 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 J 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 J 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 J 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 J 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 J 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 J 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 J 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 J 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 J 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 J 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 J 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 J 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 J 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 J 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 J 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 J 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 J 547 MET
SEQRES 1 K 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 K 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 K 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 K 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 K 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 K 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 K 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 K 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 K 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 K 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 K 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 K 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 K 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 K 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 K 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 K 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 K 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 K 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 K 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 K 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 K 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 K 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 K 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 K 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 K 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 K 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 K 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 K 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 K 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 K 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 K 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 K 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 K 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 K 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 K 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 K 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 K 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 K 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 K 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 K 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 K 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 K 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 K 547 MET
SEQRES 1 L 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 L 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 L 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 L 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 L 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 L 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 L 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 L 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 L 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 L 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 L 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 L 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 L 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 L 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 L 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 L 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 L 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 L 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 L 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 L 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 L 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 L 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 L 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 L 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 L 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 L 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 L 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 L 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 L 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 L 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 L 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 L 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 L 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 L 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 L 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 L 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 L 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 L 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 L 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 L 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 L 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 L 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 L 547 MET
SEQRES 1 M 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 M 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 M 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 M 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 M 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 M 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 M 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 M 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 M 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 M 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 M 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 M 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 M 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 M 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 M 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 M 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 M 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 M 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 M 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 M 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 M 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 M 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 M 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 M 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 M 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 M 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 M 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 M 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 M 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 M 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 M 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 M 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 M 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 M 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 M 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 M 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 M 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 M 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 M 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 M 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 M 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 M 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 M 547 MET
SEQRES 1 N 547 ALA ALA LYS ASP VAL LYS PHE GLY ASN ASP ALA ARG VAL
SEQRES 2 N 547 LYS MET LEU ARG GLY VAL ASN VAL LEU ALA ASP ALA VAL
SEQRES 3 N 547 LYS VAL THR LEU GLY PRO LYS GLY ARG ASN VAL VAL LEU
SEQRES 4 N 547 ASP LYS SER PHE GLY ALA PRO THR ILE THR LYS ASP GLY
SEQRES 5 N 547 VAL SER VAL ALA ARG GLU ILE GLU LEU GLU ASP LYS PHE
SEQRES 6 N 547 GLU ASN MET GLY ALA GLN MET VAL LYS GLU VAL ALA SER
SEQRES 7 N 547 LYS ALA ASN ASP ALA ALA GLY ASP GLY THR THR THR ALA
SEQRES 8 N 547 THR VAL LEU ALA GLN ALA ILE ILE THR GLU GLY LEU LYS
SEQRES 9 N 547 ALA VAL ALA ALA GLY MET ASN PRO MET ASP LEU LYS ARG
SEQRES 10 N 547 GLY ILE ASP LYS ALA VAL THR ALA ALA VAL GLU GLU LEU
SEQRES 11 N 547 LYS ALA LEU SER VAL PRO CYS SER ASP SER LYS ALA ILE
SEQRES 12 N 547 ALA GLN VAL GLY THR ILE SER ALA ASN SER ASP GLU THR
SEQRES 13 N 547 VAL GLY LYS LEU ILE ALA GLU ALA MET ASP LYS VAL GLY
SEQRES 14 N 547 LYS GLU GLY VAL ILE THR VAL GLU ASP GLY THR GLY LEU
SEQRES 15 N 547 GLN ASP GLU LEU ASP VAL VAL GLU GLY MET GLN PHE ASP
SEQRES 16 N 547 ARG GLY TYR LEU SER PRO TYR PHE ILE ASN LYS PRO GLU
SEQRES 17 N 547 THR GLY ALA VAL GLU LEU GLU SER PRO PHE ILE LEU LEU
SEQRES 18 N 547 ALA ASP LYS LYS ILE SER ASN ILE ARG GLU MET LEU PRO
SEQRES 19 N 547 VAL LEU GLU ALA VAL ALA LYS ALA GLY LYS PRO LEU LEU
SEQRES 20 N 547 ILE ILE ALA GLU ASP VAL GLU GLY GLU ALA LEU ALA THR
SEQRES 21 N 547 LEU VAL VAL ASN THR MET ARG GLY ILE VAL LYS VAL ALA
SEQRES 22 N 547 ALA VAL LYS ALA PRO GLY PHE GLY ASP ARG ARG LYS ALA
SEQRES 23 N 547 MET LEU GLN ASP ILE ALA THR LEU THR GLY GLY THR VAL
SEQRES 24 N 547 ILE SER GLU GLU ILE GLY MET GLU LEU GLU LYS ALA THR
SEQRES 25 N 547 LEU GLU ASP LEU GLY GLN ALA LYS ARG VAL VAL ILE ASN
SEQRES 26 N 547 LYS ASP THR THR THR ILE ILE ASP GLY VAL GLY GLU GLU
SEQRES 27 N 547 ALA ALA ILE GLN GLY ARG VAL ALA GLN ILE ARG GLN GLN
SEQRES 28 N 547 ILE GLU GLU ALA THR SER ASP TYR ASP ARG GLU LYS LEU
SEQRES 29 N 547 GLN GLU ARG VAL ALA LYS LEU ALA GLY GLY VAL ALA VAL
SEQRES 30 N 547 ILE LYS VAL GLY ALA ALA THR GLU VAL GLU MET LYS GLU
SEQRES 31 N 547 LYS LYS ALA ARG VAL GLU ASP ALA LEU HIS ALA THR ARG
SEQRES 32 N 547 ALA ALA VAL GLU GLU GLY VAL VAL ALA GLY GLY GLY VAL
SEQRES 33 N 547 ALA LEU ILE ARG VAL ALA SER LYS LEU ALA ASP LEU ARG
SEQRES 34 N 547 GLY GLN ASN GLU ASP GLN ASN VAL GLY ILE LYS VAL ALA
SEQRES 35 N 547 LEU ARG ALA MET GLU ALA PRO LEU ARG GLN ILE VAL LEU
SEQRES 36 N 547 ASN CYS GLY GLU GLU PRO SER VAL VAL ALA ASN THR VAL
SEQRES 37 N 547 LYS GLY GLY ASP GLY ASN TYR GLY TYR ASN ALA ALA THR
SEQRES 38 N 547 GLU GLU TYR GLY ASN MET ILE ASP MET GLY ILE LEU ASP
SEQRES 39 N 547 PRO THR LYS VAL THR ARG SER ALA LEU GLN TYR ALA ALA
SEQRES 40 N 547 SER VAL ALA GLY LEU MET ILE THR THR GLU CYS MET VAL
SEQRES 41 N 547 THR ASP LEU PRO LYS ASN ASP ALA ALA ASP LEU GLY ALA
SEQRES 42 N 547 ALA GLY GLY MET GLY GLY MET GLY GLY MET GLY GLY MET
SEQRES 43 N 547 MET
SEQRES 1 O 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 O 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 O 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 O 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 O 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 O 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 O 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 O 97 LEU ALA ILE VAL GLU ALA
SEQRES 1 P 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 P 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 P 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 P 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 P 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 P 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 P 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 P 97 LEU ALA ILE VAL GLU ALA
SEQRES 1 Q 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 Q 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 Q 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 Q 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 Q 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 Q 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 Q 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 Q 97 LEU ALA ILE VAL GLU ALA
SEQRES 1 R 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 R 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 R 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 R 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 R 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 R 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 R 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 R 97 LEU ALA ILE VAL GLU ALA
SEQRES 1 S 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 S 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 S 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 S 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 S 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 S 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 S 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 S 97 LEU ALA ILE VAL GLU ALA
SEQRES 1 T 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 T 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 T 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 T 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 T 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 T 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 T 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 T 97 LEU ALA ILE VAL GLU ALA
SEQRES 1 U 97 MET ASN ILE ARG PRO LEU HIS ASP ARG VAL ILE VAL LYS
SEQRES 2 U 97 ARG LYS GLU VAL GLU THR LYS SER ALA GLY GLY ILE VAL
SEQRES 3 U 97 LEU THR GLY SER ALA ALA ALA LYS SER THR ARG GLY GLU
SEQRES 4 U 97 VAL LEU ALA VAL GLY ASN GLY ARG ILE LEU GLU ASN GLY
SEQRES 5 U 97 GLU VAL LYS PRO LEU ASP VAL LYS VAL GLY ASP ILE VAL
SEQRES 6 U 97 ILE PHE ASN ASP GLY TYR GLY VAL LYS SER GLU LYS ILE
SEQRES 7 U 97 ASP ASN GLU GLU VAL LEU ILE MET SER GLU SER ASP ILE
SEQRES 8 U 97 LEU ALA ILE VAL GLU ALA
HELIX 1 1 GLY A 9 VAL A 29 1 21
HELIX 2 2 ASP A 52 GLU A 59 1 8
HELIX 3 3 ASP A 64 GLY A 86 1 23
HELIX 4 4 GLY A 88 GLY A 110 1 23
HELIX 5 5 ASN A 112 LEU A 131 1 20
HELIX 6 6 LYS A 132 LEU A 134 5 3
HELIX 7 7 ASP A 140 ILE A 150 1 11
HELIX 8 8 ASP A 155 GLY A 170 1 16
HELIX 9 9 ASN A 229 GLU A 232 5 4
HELIX 10 10 MET A 233 GLY A 244 1 12
HELIX 11 11 GLU A 255 ARG A 268 1 14
HELIX 12 12 ASP A 283 GLY A 297 1 15
HELIX 13 13 GLU A 304 GLY A 306 5 3
HELIX 14 14 GLU A 308 ALA A 312 5 5
HELIX 15 15 THR A 313 LEU A 317 5 5
HELIX 16 16 GLU A 338 GLU A 354 1 17
HELIX 17 17 SER A 358 GLU A 367 1 10
HELIX 18 18 ARG A 368 ALA A 373 1 6
HELIX 19 19 THR A 385 LEU A 400 1 16
HELIX 20 20 ALA A 402 GLU A 408 1 7
HELIX 21 21 GLY A 416 LYS A 425 1 10
HELIX 22 22 ASN A 433 MET A 447 1 15
HELIX 23 23 GLU A 448 GLY A 459 1 12
HELIX 24 24 GLU A 461 GLY A 472 1 12
HELIX 25 25 MET A 488 GLY A 492 1 5
HELIX 26 26 THR A 497 ILE A 515 1 19
HELIX 27 27 GLY B 9 LYS B 28 1 20
HELIX 28 28 VAL B 29 LEU B 31 5 3
HELIX 29 29 ASP B 52 GLU B 59 1 8
HELIX 30 30 ASP B 64 GLY B 86 1 23
HELIX 31 31 GLY B 88 GLY B 110 1 23
HELIX 32 32 ASN B 112 LEU B 131 1 20
HELIX 33 33 LYS B 132 LEU B 134 5 3
HELIX 34 34 ASP B 140 ALA B 152 1 13
HELIX 35 35 ASP B 155 GLY B 170 1 16
HELIX 36 36 SER B 201 ILE B 205 5 5
HELIX 37 37 ASN B 229 GLU B 232 5 4
HELIX 38 38 MET B 233 GLY B 244 1 12
HELIX 39 39 GLU B 255 ARG B 268 1 14
HELIX 40 40 PHE B 281 GLY B 297 1 17
HELIX 41 41 SER B 302 GLY B 306 5 5
HELIX 42 42 GLU B 308 ALA B 312 5 5
HELIX 43 43 GLU B 338 GLU B 355 1 18
HELIX 44 44 SER B 358 LYS B 371 1 14
HELIX 45 45 THR B 385 LEU B 400 1 16
HELIX 46 46 ALA B 402 GLY B 410 1 9
HELIX 47 47 GLY B 416 LYS B 425 1 10
HELIX 48 48 ASN B 433 GLU B 448 1 16
HELIX 49 49 GLU B 448 CYS B 458 1 11
HELIX 50 50 GLU B 461 LYS B 470 1 10
HELIX 51 51 THR B 497 ILE B 515 1 19
HELIX 52 52 GLY C 9 LYS C 28 1 20
HELIX 53 53 VAL C 29 LEU C 31 5 3
HELIX 54 54 ASP C 52 GLU C 59 1 8
HELIX 55 55 ASP C 64 GLY C 86 1 23
HELIX 56 56 GLY C 88 GLY C 110 1 23
HELIX 57 57 ASN C 112 SER C 135 1 24
HELIX 58 58 ASP C 140 ALA C 152 1 13
HELIX 59 59 ASP C 155 GLY C 170 1 16
HELIX 60 60 SER C 201 ILE C 205 5 5
HELIX 61 61 ILE C 230 GLU C 232 5 3
HELIX 62 62 MET C 233 ALA C 243 1 11
HELIX 63 63 GLU C 257 ARG C 268 1 12
HELIX 64 64 ASP C 283 GLY C 297 1 15
HELIX 65 65 SER C 302 GLY C 306 5 5
HELIX 66 66 GLU C 338 GLU C 354 1 17
HELIX 67 67 SER C 358 ALA C 373 1 16
HELIX 68 68 THR C 385 LEU C 400 1 16
HELIX 69 69 ALA C 402 GLY C 410 1 9
HELIX 70 70 GLY C 416 ALA C 427 1 12
HELIX 71 71 ASN C 433 MET C 447 1 15
HELIX 72 72 GLU C 448 GLY C 459 1 12
HELIX 73 73 GLU C 461 LYS C 470 1 10
HELIX 74 74 THR C 497 ILE C 515 1 19
HELIX 75 75 GLY D 9 LYS D 28 1 20
HELIX 76 76 VAL D 29 LEU D 31 5 3
HELIX 77 77 ASP D 52 GLU D 59 1 8
HELIX 78 78 ASP D 64 GLY D 86 1 23
HELIX 79 79 GLY D 88 GLY D 110 1 23
HELIX 80 80 ASN D 112 SER D 135 1 24
HELIX 81 81 ASP D 140 ALA D 152 1 13
HELIX 82 82 ASP D 155 GLY D 170 1 16
HELIX 83 83 SER D 201 ILE D 205 5 5
HELIX 84 84 ASN D 229 LYS D 242 1 14
HELIX 85 85 GLU D 255 ARG D 268 1 14
HELIX 86 86 PHE D 281 GLY D 297 1 17
HELIX 87 87 SER D 302 GLY D 306 5 5
HELIX 88 88 GLU D 308 ALA D 312 5 5
HELIX 89 89 THR D 313 LEU D 317 5 5
HELIX 90 90 GLU D 338 GLU D 354 1 17
HELIX 91 91 SER D 358 ALA D 373 1 16
HELIX 92 92 THR D 385 LEU D 400 1 16
HELIX 93 93 ALA D 402 GLY D 410 1 9
HELIX 94 94 GLY D 416 LYS D 425 1 10
HELIX 95 95 ASN D 433 GLU D 448 1 16
HELIX 96 96 GLU D 448 GLY D 459 1 12
HELIX 97 97 GLU D 461 GLY D 472 1 12
HELIX 98 98 THR D 497 ILE D 515 1 19
HELIX 99 99 GLY E 9 LYS E 28 1 20
HELIX 100 100 VAL E 29 LEU E 31 5 3
HELIX 101 101 ASP E 52 GLU E 59 1 8
HELIX 102 102 ASP E 64 GLY E 86 1 23
HELIX 103 103 GLY E 88 GLY E 110 1 23
HELIX 104 104 ASN E 112 SER E 135 1 24
HELIX 105 105 ASP E 140 ALA E 152 1 13
HELIX 106 106 ASP E 155 GLY E 170 1 16
HELIX 107 107 SER E 201 ILE E 205 5 5
HELIX 108 108 ASN E 229 GLU E 232 5 4
HELIX 109 109 MET E 233 GLY E 244 1 12
HELIX 110 110 GLU E 255 ARG E 268 1 14
HELIX 111 111 GLY E 282 GLY E 297 1 16
HELIX 112 112 SER E 302 GLY E 306 5 5
HELIX 113 113 GLU E 308 ALA E 312 5 5
HELIX 114 114 GLU E 338 GLU E 354 1 17
HELIX 115 115 SER E 358 GLY E 374 1 17
HELIX 116 116 THR E 385 LEU E 400 1 16
HELIX 117 117 ALA E 402 GLY E 410 1 9
HELIX 118 118 GLY E 416 SER E 424 1 9
HELIX 119 119 ASN E 433 MET E 447 1 15
HELIX 120 120 GLU E 448 CYS E 458 1 11
HELIX 121 121 GLU E 461 GLY E 472 1 12
HELIX 122 122 THR E 497 ILE E 515 1 19
HELIX 123 123 GLY F 9 LYS F 28 1 20
HELIX 124 124 VAL F 29 LEU F 31 5 3
HELIX 125 125 ASP F 52 ARG F 58 1 7
HELIX 126 126 ASP F 64 GLY F 86 1 23
HELIX 127 127 GLY F 88 GLY F 110 1 23
HELIX 128 128 ASN F 112 LEU F 131 1 20
HELIX 129 129 LYS F 132 LEU F 134 5 3
HELIX 130 130 ASP F 140 ALA F 152 1 13
HELIX 131 131 ASP F 155 GLY F 170 1 16
HELIX 132 132 MET F 233 GLY F 244 1 12
HELIX 133 133 GLU F 255 ARG F 268 1 14
HELIX 134 134 ASP F 283 GLY F 297 1 15
HELIX 135 135 SER F 302 GLY F 306 5 5
HELIX 136 136 GLU F 308 ALA F 312 5 5
HELIX 137 137 GLU F 338 GLU F 354 1 17
HELIX 138 138 SER F 358 LYS F 371 1 14
HELIX 139 139 THR F 385 LEU F 400 1 16
HELIX 140 140 ALA F 402 GLY F 410 1 9
HELIX 141 141 GLY F 416 LYS F 425 1 10
HELIX 142 142 ASN F 433 MET F 447 1 15
HELIX 143 143 GLU F 448 CYS F 458 1 11
HELIX 144 144 GLU F 461 GLY F 472 1 12
HELIX 145 145 THR F 497 ILE F 515 1 19
HELIX 146 146 GLY G 9 LYS G 28 1 20
HELIX 147 147 VAL G 29 LEU G 31 5 3
HELIX 148 148 ASP G 52 ARG G 58 1 7
HELIX 149 149 ASP G 64 GLY G 86 1 23
HELIX 150 150 GLY G 88 GLY G 110 1 23
HELIX 151 151 ASN G 112 SER G 135 1 24
HELIX 152 152 ASP G 140 ALA G 152 1 13
HELIX 153 153 ASP G 155 GLY G 170 1 16
HELIX 154 154 SER G 201 ILE G 205 5 5
HELIX 155 155 ASN G 229 GLU G 232 5 4
HELIX 156 156 MET G 233 LYS G 242 1 10
HELIX 157 157 GLU G 255 ARG G 268 1 14
HELIX 158 158 ASP G 283 GLY G 297 1 15
HELIX 159 159 GLU G 304 GLY G 306 5 3
HELIX 160 160 GLU G 308 ALA G 312 5 5
HELIX 161 161 GLU G 338 GLU G 355 1 18
HELIX 162 162 SER G 358 GLU G 367 1 10
HELIX 163 163 THR G 385 LEU G 400 1 16
HELIX 164 164 ALA G 402 GLY G 410 1 9
HELIX 165 165 GLY G 416 LEU G 426 1 11
HELIX 166 166 ASN G 433 ALA G 446 1 14
HELIX 167 167 GLU G 448 CYS G 458 1 11
HELIX 168 168 GLU G 461 LYS G 470 1 10
HELIX 169 169 THR G 497 ILE G 515 1 19
HELIX 170 170 GLY H 9 LYS H 28 1 20
HELIX 171 171 VAL H 29 LEU H 31 5 3
HELIX 172 172 ASP H 52 GLU H 59 1 8
HELIX 173 173 ASP H 64 ALA H 84 1 21
HELIX 174 174 GLY H 88 ALA H 109 1 22
HELIX 175 175 ASN H 112 SER H 135 1 24
HELIX 176 176 ASP H 140 ALA H 152 1 13
HELIX 177 177 THR H 157 GLY H 170 1 14
HELIX 178 178 SER H 201 ILE H 205 5 5
HELIX 179 179 GLU H 232 GLY H 244 1 13
HELIX 180 180 GLU H 257 GLY H 269 1 13
HELIX 181 181 PHE H 281 ARG H 284 5 4
HELIX 182 182 ARG H 285 GLY H 297 1 13
HELIX 183 183 GLU H 308 ALA H 312 5 5
HELIX 184 184 THR H 313 LEU H 317 5 5
HELIX 185 185 GLU H 338 GLU H 354 1 17
HELIX 186 186 SER H 358 LYS H 371 1 14
HELIX 187 187 THR H 385 LEU H 400 1 16
HELIX 188 188 ALA H 402 VAL H 407 1 6
HELIX 189 189 GLY H 416 ALA H 427 1 12
HELIX 190 190 ASN H 433 MET H 447 1 15
HELIX 191 191 GLU H 448 CYS H 458 1 11
HELIX 192 192 GLU H 461 GLY H 472 1 12
HELIX 193 193 PRO H 496 THR H 516 1 21
HELIX 194 194 GLY I 9 LYS I 28 1 20
HELIX 195 195 VAL I 29 GLY I 32 5 4
HELIX 196 196 ASP I 52 ILE I 60 1 9
HELIX 197 197 ASP I 64 ALA I 85 1 22
HELIX 198 198 GLY I 88 ALA I 108 1 21
HELIX 199 199 ASN I 112 SER I 135 1 24
HELIX 200 200 ASP I 140 ALA I 152 1 13
HELIX 201 201 ASP I 155 GLY I 170 1 16
HELIX 202 202 SER I 201 ILE I 205 5 5
HELIX 203 203 ASN I 229 GLU I 232 5 4
HELIX 204 204 MET I 233 GLY I 244 1 12
HELIX 205 205 GLU I 255 MET I 267 1 13
HELIX 206 206 ASP I 283 GLY I 297 1 15
HELIX 207 207 GLU I 308 ALA I 312 5 5
HELIX 208 208 THR I 313 LEU I 317 5 5
HELIX 209 209 GLU I 338 GLU I 354 1 17
HELIX 210 210 SER I 358 LYS I 371 1 14
HELIX 211 211 THR I 385 LEU I 400 1 16
HELIX 212 212 ALA I 402 GLU I 408 1 7
HELIX 213 213 GLY I 416 LYS I 425 1 10
HELIX 214 214 ASN I 433 MET I 447 1 15
HELIX 215 215 GLU I 448 GLY I 459 1 12
HELIX 216 216 GLU I 461 GLY I 472 1 12
HELIX 217 217 THR I 497 THR I 517 1 21
HELIX 218 218 GLY J 9 LYS J 28 1 20
HELIX 219 219 VAL J 29 LEU J 31 5 3
HELIX 220 220 ASP J 52 ILE J 60 1 9
HELIX 221 221 ASP J 64 ASP J 83 1 20
HELIX 222 222 GLY J 88 ALA J 109 1 22
HELIX 223 223 ASN J 112 LEU J 134 1 23
HELIX 224 224 ASP J 140 ALA J 152 1 13
HELIX 225 225 THR J 157 GLY J 170 1 14
HELIX 226 226 SER J 201 ILE J 205 5 5
HELIX 227 227 GLU J 232 GLY J 244 1 13
HELIX 228 228 GLU J 255 MET J 267 1 13
HELIX 229 229 PHE J 281 ASP J 283 5 3
HELIX 230 230 ARG J 284 GLY J 297 1 14
HELIX 231 231 SER J 302 GLY J 306 5 5
HELIX 232 232 GLU J 308 ALA J 312 5 5
HELIX 233 233 THR J 313 LEU J 317 5 5
HELIX 234 234 GLU J 338 GLU J 354 1 17
HELIX 235 235 SER J 358 LYS J 371 1 14
HELIX 236 236 THR J 385 LEU J 400 1 16
HELIX 237 237 ALA J 402 VAL J 407 1 6
HELIX 238 238 GLY J 416 ALA J 427 1 12
HELIX 239 239 ASN J 433 MET J 447 1 15
HELIX 240 240 GLU J 448 GLY J 459 1 12
HELIX 241 241 GLU J 461 GLY J 471 1 11
HELIX 242 242 THR J 497 THR J 517 1 21
HELIX 243 243 GLY K 9 LYS K 28 1 20
HELIX 244 244 VAL K 29 LEU K 31 5 3
HELIX 245 245 ASP K 52 ILE K 60 1 9
HELIX 246 246 PHE K 66 ASP K 83 1 18
HELIX 247 247 GLY K 88 ALA K 109 1 22
HELIX 248 248 ASN K 112 SER K 135 1 24
HELIX 249 249 ASP K 140 ALA K 152 1 13
HELIX 250 250 THR K 157 GLY K 170 1 14
HELIX 251 251 SER K 201 ILE K 205 5 5
HELIX 252 252 ILE K 230 GLU K 232 5 3
HELIX 253 253 MET K 233 GLY K 244 1 12
HELIX 254 254 GLU K 255 MET K 267 1 13
HELIX 255 255 ARG K 284 GLY K 297 1 14
HELIX 256 256 SER K 302 GLY K 306 5 5
HELIX 257 257 GLU K 308 ALA K 312 5 5
HELIX 258 258 THR K 313 LEU K 317 5 5
HELIX 259 259 GLU K 338 ILE K 353 1 16
HELIX 260 260 GLU K 354 ALA K 356 5 3
HELIX 261 261 SER K 358 GLY K 374 1 17
HELIX 262 262 THR K 385 ASP K 398 1 14
HELIX 263 263 ARG K 404 GLU K 409 1 6
HELIX 264 264 GLY K 416 ALA K 423 1 8
HELIX 265 265 ASN K 433 MET K 447 1 15
HELIX 266 266 GLU K 448 GLY K 459 1 12
HELIX 267 267 GLU K 461 LYS K 470 1 10
HELIX 268 268 MET K 488 GLY K 492 1 5
HELIX 269 269 THR K 497 THR K 517 1 21
HELIX 270 270 GLY L 9 LYS L 28 1 20
HELIX 271 271 VAL L 29 LEU L 31 5 3
HELIX 272 272 ASP L 52 ILE L 60 1 9
HELIX 273 273 ASP L 64 ALA L 84 1 21
HELIX 274 274 GLY L 88 ALA L 109 1 22
HELIX 275 275 ASN L 112 ALA L 133 1 22
HELIX 276 276 ASP L 140 ALA L 152 1 13
HELIX 277 277 THR L 157 GLY L 170 1 14
HELIX 278 278 SER L 201 ILE L 205 5 5
HELIX 279 279 ASN L 229 GLU L 232 5 4
HELIX 280 280 MET L 233 GLY L 244 1 12
HELIX 281 281 GLU L 255 MET L 267 1 13
HELIX 282 282 ARG L 284 GLY L 297 1 14
HELIX 283 283 SER L 302 GLY L 306 5 5
HELIX 284 284 GLU L 308 ALA L 312 5 5
HELIX 285 285 GLU L 338 ILE L 353 1 16
HELIX 286 286 GLU L 354 ALA L 356 5 3
HELIX 287 287 SER L 358 GLY L 374 1 17
HELIX 288 288 THR L 385 LEU L 400 1 16
HELIX 289 289 ALA L 402 GLY L 410 1 9
HELIX 290 290 GLY L 416 LYS L 425 1 10
HELIX 291 291 ASN L 433 GLU L 448 1 16
HELIX 292 292 GLU L 448 GLY L 459 1 12
HELIX 293 293 GLU L 461 LYS L 470 1 10
HELIX 294 294 THR L 497 THR L 516 1 20
HELIX 295 295 GLY M 9 LYS M 28 1 20
HELIX 296 296 VAL M 29 GLY M 32 5 4
HELIX 297 297 ASP M 52 ILE M 60 1 9
HELIX 298 298 ASP M 64 ASP M 83 1 20
HELIX 299 299 GLY M 88 ALA M 109 1 22
HELIX 300 300 ASN M 112 SER M 135 1 24
HELIX 301 301 ASP M 140 ALA M 152 1 13
HELIX 302 302 ASP M 155 GLY M 170 1 16
HELIX 303 303 SER M 201 ILE M 205 5 5
HELIX 304 304 ILE M 230 GLU M 232 5 3
HELIX 305 305 MET M 233 GLY M 244 1 12
HELIX 306 306 GLU M 257 MET M 267 1 11
HELIX 307 307 ARG M 284 GLY M 297 1 14
HELIX 308 308 THR M 313 LEU M 317 5 5
HELIX 309 309 GLU M 338 GLU M 354 1 17
HELIX 310 310 SER M 358 GLY M 374 1 17
HELIX 311 311 THR M 385 LEU M 400 1 16
HELIX 312 312 ALA M 402 GLU M 408 1 7
HELIX 313 313 GLY M 416 LYS M 425 1 10
HELIX 314 314 ASN M 433 MET M 447 1 15
HELIX 315 315 GLU M 448 CYS M 458 1 11
HELIX 316 316 GLU M 461 GLY M 471 1 11
HELIX 317 317 THR M 497 THR M 517 1 21
HELIX 318 318 GLY N 9 LYS N 28 1 20
HELIX 319 319 VAL N 29 LEU N 31 5 3
HELIX 320 320 ASP N 52 GLU N 59 1 8
HELIX 321 321 ASP N 64 GLY N 86 1 23
HELIX 322 322 GLY N 88 ALA N 109 1 22
HELIX 323 323 ASN N 112 SER N 135 1 24
HELIX 324 324 ASP N 140 ALA N 152 1 13
HELIX 325 325 ASP N 155 GLY N 170 1 16
HELIX 326 326 SER N 201 ILE N 205 5 5
HELIX 327 327 ASN N 229 GLU N 232 5 4
HELIX 328 328 MET N 233 GLY N 244 1 12
HELIX 329 329 GLU N 257 MET N 267 1 11
HELIX 330 330 PHE N 281 ASP N 283 5 3
HELIX 331 331 ARG N 284 GLY N 297 1 14
HELIX 332 332 SER N 302 GLY N 306 5 5
HELIX 333 333 GLU N 308 ALA N 312 5 5
HELIX 334 334 GLU N 338 ILE N 353 1 16
HELIX 335 335 GLU N 354 ALA N 356 5 3
HELIX 336 336 SER N 358 GLY N 374 1 17
HELIX 337 337 THR N 385 LEU N 400 1 16
HELIX 338 338 ALA N 402 GLU N 408 1 7
HELIX 339 339 GLY N 416 ALA N 427 1 12
HELIX 340 340 ASN N 433 GLU N 448 1 16
HELIX 341 341 GLU N 448 CYS N 458 1 11
HELIX 342 342 SER N 463 GLY N 472 1 10
HELIX 343 343 PRO N 496 THR N 517 1 22
HELIX 344 344 SER T 87 SER T 89 5 3
HELIX 345 345 THR U 19 ALA U 22 5 4
SHEET 1 AA 4 LYS A 4 PHE A 8 0
SHEET 2 AA 4 THR A 517 ASP A 523 -1 O MET A 520 N LYS A 7
SHEET 3 AA 4 ASN G 37 LEU G 40 1 O ASN G 37 N GLU A 518
SHEET 4 AA 4 THR G 48 THR G 50 -1 O THR G 48 N LEU G 40
SHEET 1 AB 4 THR A 48 THR A 50 0
SHEET 2 AB 4 ASN A 37 LEU A 40 -1 O VAL A 38 N THR A 50
SHEET 3 AB 4 THR B 517 ASP B 523 1 N GLU B 518 O ASN A 37
SHEET 4 AB 4 LYS B 4 PHE B 8 -1 O ASP B 5 N THR B 522
SHEET 1 AC 3 VAL A 174 ASP A 179 0
SHEET 2 AC 3 VAL A 376 VAL A 381 1 O ALA A 377 N THR A 176
SHEET 3 AC 3 GLU A 186 VAL A 190 -1 O GLU A 186 N LYS A 380
SHEET 1 AD 4 MET A 193 ASP A 196 0
SHEET 2 AD 4 THR A 329 GLY A 335 -1 O THR A 330 N PHE A 195
SHEET 3 AD 4 GLY A 318 ILE A 325 -1 N LYS A 321 O ASP A 334
SHEET 4 AD 4 VAL A 213 GLU A 216 -1 O VAL A 213 N ILE A 325
SHEET 1 AE 4 MET A 193 ASP A 196 0
SHEET 2 AE 4 THR A 329 GLY A 335 -1 O THR A 330 N PHE A 195
SHEET 3 AE 4 GLY A 318 ILE A 325 -1 N LYS A 321 O ASP A 334
SHEET 4 AE 4 PHE A 219 ILE A 227 -1 O ILE A 220 N GLY A 318
SHEET 1 AF 2 VAL A 411 ALA A 413 0
SHEET 2 AF 2 LEU A 494 PRO A 496 -1 O ASP A 495 N VAL A 412
SHEET 1 AG 2 TYR A 476 TYR A 478 0
SHEET 2 AG 2 TYR A 485 ASN A 487 -1 O GLY A 486 N GLY A 477
SHEET 1 BA 4 THR B 48 THR B 50 0
SHEET 2 BA 4 ASN B 37 LEU B 40 -1 O VAL B 38 N THR B 50
SHEET 3 BA 4 THR C 517 ASP C 523 1 N GLU C 518 O ASN B 37
SHEET 4 BA 4 LYS C 4 PHE C 8 -1 O ASP C 5 N THR C 522
SHEET 1 BB 3 VAL B 174 ASP B 179 0
SHEET 2 BB 3 VAL B 376 VAL B 381 1 O ALA B 377 N THR B 176
SHEET 3 BB 3 GLU B 186 VAL B 190 -1 O GLU B 186 N LYS B 380
SHEET 1 BC 4 MET B 193 PHE B 195 0
SHEET 2 BC 4 THR B 330 GLY B 335 -1 O THR B 330 N PHE B 195
SHEET 3 BC 4 GLY B 318 ILE B 325 -1 N LYS B 321 O ASP B 334
SHEET 4 BC 4 VAL B 213 GLU B 216 -1 O VAL B 213 N ILE B 325
SHEET 1 BD 4 MET B 193 PHE B 195 0
SHEET 2 BD 4 THR B 330 GLY B 335 -1 O THR B 330 N PHE B 195
SHEET 3 BD 4 GLY B 318 ILE B 325 -1 N LYS B 321 O ASP B 334
SHEET 4 BD 4 PHE B 219 ALA B 223 -1 O ILE B 220 N GLY B 318
SHEET 1 BE 2 VAL B 411 ALA B 413 0
SHEET 2 BE 2 LEU B 494 PRO B 496 -1 O ASP B 495 N VAL B 412
SHEET 1 BF 2 TYR B 476 ASN B 479 0
SHEET 2 BF 2 GLU B 484 ASN B 487 -1 O GLU B 484 N ASN B 479
SHEET 1 CA 4 THR C 48 THR C 50 0
SHEET 2 CA 4 ASN C 37 LEU C 40 -1 O VAL C 38 N THR C 50
SHEET 3 CA 4 THR D 517 ASP D 523 1 N GLU D 518 O ASN C 37
SHEET 4 CA 4 LYS D 4 PHE D 8 -1 O ASP D 5 N THR D 522
SHEET 1 CB 3 ILE C 175 GLU C 178 0
SHEET 2 CB 3 VAL C 376 LYS C 380 1 O ALA C 377 N THR C 176
SHEET 3 CB 3 GLU C 186 VAL C 190 -1 O GLU C 186 N LYS C 380
SHEET 1 CC 4 MET C 193 PHE C 195 0
SHEET 2 CC 4 THR C 330 GLY C 335 -1 O THR C 330 N PHE C 195
SHEET 3 CC 4 GLY C 318 ILE C 325 -1 N LYS C 321 O ILE C 333
SHEET 4 CC 4 VAL C 213 GLU C 216 -1 O VAL C 213 N ILE C 325
SHEET 1 CD 4 MET C 193 PHE C 195 0
SHEET 2 CD 4 THR C 330 GLY C 335 -1 O THR C 330 N PHE C 195
SHEET 3 CD 4 GLY C 318 ILE C 325 -1 N LYS C 321 O ILE C 333
SHEET 4 CD 4 PHE C 219 ALA C 223 -1 O ILE C 220 N GLY C 318
SHEET 1 CE 2 VAL C 411 ALA C 413 0
SHEET 2 CE 2 LEU C 494 PRO C 496 -1 O ASP C 495 N VAL C 412
SHEET 1 CF 2 TYR C 476 ASN C 479 0
SHEET 2 CF 2 GLU C 484 ASN C 487 -1 O GLU C 484 N ASN C 479
SHEET 1 DA 4 ALA D 46 THR D 50 0
SHEET 2 DA 4 ASN D 37 LYS D 42 -1 O VAL D 38 N THR D 50
SHEET 3 DA 4 THR E 517 ASP E 523 1 N GLU E 518 O ASN D 37
SHEET 4 DA 4 LYS E 4 PHE E 8 -1 O ASP E 5 N THR E 522
SHEET 1 DB 3 VAL D 174 ASP D 179 0
SHEET 2 DB 3 VAL D 376 VAL D 381 1 O ALA D 377 N THR D 176
SHEET 3 DB 3 GLU D 186 VAL D 190 -1 O GLU D 186 N LYS D 380
SHEET 1 DC 9 MET D 193 PHE D 195 0
SHEET 2 DC 9 THR D 330 GLY D 335 -1 O THR D 330 N PHE D 195
SHEET 3 DC 9 GLY D 318 ILE D 325 -1 N LYS D 321 O ASP D 334
SHEET 4 DC 9 VAL D 213 GLU D 216 -1 O VAL D 213 N ILE D 325
SHEET 5 DC 9 GLY D 318 ILE D 325 -1 O VAL D 323 N LEU D 215
SHEET 6 DC 9 VAL D 273 VAL D 276
SHEET 7 DC 9 LEU D 247 VAL D 254 1 O LEU D 247 N ALA D 274
SHEET 8 DC 9 PHE D 219 ILE D 227 1 O PHE D 219 N LEU D 248
SHEET 9 DC 9 GLY D 318 ILE D 325 -1 O GLY D 318 N ILE D 220
SHEET 1 DD 2 VAL D 411 ALA D 413 0
SHEET 2 DD 2 LEU D 494 PRO D 496 -1 O ASP D 495 N VAL D 412
SHEET 1 DE 2 TYR D 476 ASN D 479 0
SHEET 2 DE 2 GLU D 484 ASN D 487 -1 O GLU D 484 N ASN D 479
SHEET 1 EA 4 THR E 48 THR E 50 0
SHEET 2 EA 4 ASN E 37 LEU E 40 -1 O VAL E 38 N THR E 50
SHEET 3 EA 4 THR F 517 ASP F 523 1 N GLU F 518 O ASN E 37
SHEET 4 EA 4 LYS F 4 PHE F 8 -1 O ASP F 5 N THR F 522
SHEET 1 EB 3 ILE E 175 GLY E 182 0
SHEET 2 EB 3 GLY E 375 GLY E 382 1 O ALA E 377 N THR E 176
SHEET 3 EB 3 GLU E 186 GLU E 191 -1 O GLU E 186 N LYS E 380
SHEET 1 EC10 MET E 193 PHE E 195 0
SHEET 2 EC10 THR E 330 GLY E 335 -1 O THR E 330 N PHE E 195
SHEET 3 EC10 GLY E 318 ILE E 325 -1 N LYS E 321 O ASP E 334
SHEET 4 EC10 VAL E 213 GLU E 216 -1 O VAL E 213 N ILE E 325
SHEET 5 EC10 GLY E 318 ILE E 325 -1 O VAL E 323 N LEU E 215
SHEET 6 EC10 VAL E 273 VAL E 276
SHEET 7 EC10 LEU E 247 ALA E 251 1 O LEU E 247 N ALA E 274
SHEET 8 EC10 PHE E 219 ALA E 223 1 O PHE E 219 N LEU E 248
SHEET 9 EC10 VAL E 300 ILE E 301 1 N ILE E 301 O LEU E 222
SHEET 10 EC10 PHE E 219 ALA E 223 1 O LEU E 222 N ILE E 301
SHEET 1 ED 2 VAL E 411 ALA E 413 0
SHEET 2 ED 2 LEU E 494 PRO E 496 -1 O ASP E 495 N VAL E 412
SHEET 1 EE 2 TYR E 476 ASN E 479 0
SHEET 2 EE 2 GLU E 484 ASN E 487 -1 O GLU E 484 N ASN E 479
SHEET 1 FA 4 THR F 48 THR F 50 0
SHEET 2 FA 4 ASN F 37 LEU F 40 -1 O VAL F 38 N THR F 50
SHEET 3 FA 4 THR G 517 ASP G 523 1 N GLU G 518 O ASN F 37
SHEET 4 FA 4 LYS G 4 PHE G 8 -1 O ASP G 5 N THR G 522
SHEET 1 FB 3 VAL F 174 GLY F 182 0
SHEET 2 FB 3 VAL F 376 GLY F 382 1 O ALA F 377 N THR F 176
SHEET 3 FB 3 GLU F 186 VAL F 190 -1 O GLU F 186 N LYS F 380
SHEET 1 FC10 MET F 193 PHE F 195 0
SHEET 2 FC10 THR F 330 GLY F 335 -1 O THR F 330 N PHE F 195
SHEET 3 FC10 GLY F 318 ILE F 325 -1 N LYS F 321 O ASP F 334
SHEET 4 FC10 VAL F 213 GLU F 216 -1 O VAL F 213 N ILE F 325
SHEET 5 FC10 GLY F 318 ILE F 325 -1 O VAL F 323 N LEU F 215
SHEET 6 FC10 VAL F 273 LYS F 277
SHEET 7 FC10 LEU F 247 VAL F 254 1 O LEU F 247 N ALA F 274
SHEET 8 FC10 PHE F 219 ILE F 227 1 O PHE F 219 N LEU F 248
SHEET 9 FC10 VAL F 300 ILE F 301 1 O ILE F 301 N ASP F 224
SHEET 10 FC10 PHE F 219 ILE F 227 1 O LEU F 222 N ILE F 301
SHEET 1 FD 2 VAL F 411 ALA F 413 0
SHEET 2 FD 2 LEU F 494 PRO F 496 -1 O ASP F 495 N VAL F 412
SHEET 1 FE 2 TYR F 476 TYR F 478 0
SHEET 2 FE 2 TYR F 485 ASN F 487 -1 O GLY F 486 N GLY F 477
SHEET 1 GA 3 VAL G 174 ASP G 179 0
SHEET 2 GA 3 VAL G 376 VAL G 381 1 O ALA G 377 N THR G 176
SHEET 3 GA 3 GLU G 186 VAL G 190 -1 O GLU G 186 N LYS G 380
SHEET 1 GB10 MET G 193 PHE G 195 0
SHEET 2 GB10 THR G 330 GLY G 335 -1 O THR G 330 N PHE G 195
SHEET 3 GB10 GLY G 318 ILE G 325 -1 N LYS G 321 O ASP G 334
SHEET 4 GB10 VAL G 213 GLU G 216 -1 O VAL G 213 N ILE G 325
SHEET 5 GB10 GLY G 318 ILE G 325 -1 O VAL G 323 N LEU G 215
SHEET 6 GB10 VAL G 273 VAL G 276
SHEET 7 GB10 LEU G 247 ILE G 250 1 O LEU G 247 N ALA G 274
SHEET 8 GB10 PHE G 219 ASP G 224 1 O PHE G 219 N LEU G 248
SHEET 9 GB10 VAL G 300 SER G 302 1 O ILE G 301 N ASP G 224
SHEET 10 GB10 PHE G 219 ASP G 224 1 O LEU G 222 N ILE G 301
SHEET 1 GC 2 LYS G 226 ILE G 227 0
SHEET 2 GC 2 ASP G 253 VAL G 254 1 O ASP G 253 N ILE G 227
SHEET 1 GD 2 VAL G 411 ALA G 413 0
SHEET 2 GD 2 LEU G 494 PRO G 496 -1 O ASP G 495 N VAL G 412
SHEET 1 GE 2 TYR G 476 TYR G 478 0
SHEET 2 GE 2 TYR G 485 ASN G 487 -1 O GLY G 486 N GLY G 477
SHEET 1 HA 4 LYS H 4 PHE H 8 0
SHEET 2 HA 4 THR H 517 ASP H 523 -1 O MET H 520 N LYS H 7
SHEET 3 HA 4 ASN I 37 LEU I 40 1 O ASN I 37 N GLU H 518
SHEET 4 HA 4 THR I 48 THR I 50 -1 O THR I 48 N LEU I 40
SHEET 1 HB 4 THR H 48 THR H 50 0
SHEET 2 HB 4 VAL H 38 LEU H 40 -1 O VAL H 38 N THR H 50
SHEET 3 HB 4 CYS N 519 ASP N 523 1 O CYS N 519 N VAL H 39
SHEET 4 HB 4 LYS N 4 PHE N 8 -1 O ASP N 5 N THR N 522
SHEET 1 HC 3 VAL H 174 GLU H 178 0
SHEET 2 HC 3 VAL H 376 LYS H 380 1 O ALA H 377 N THR H 176
SHEET 3 HC 3 GLU H 186 VAL H 190 -1 O GLU H 186 N LYS H 380
SHEET 1 HD 9 GLY H 192 PHE H 195 0
SHEET 2 HD 9 THR H 330 GLY H 335 -1 O THR H 330 N PHE H 195
SHEET 3 HD 9 GLY H 318 ASN H 326 -1 N LYS H 321 O ASP H 334
SHEET 4 HD 9 ALA H 212 GLU H 216 -1 O VAL H 213 N ILE H 325
SHEET 5 HD 9 GLY H 318 ASN H 326 -1 O VAL H 323 N LEU H 215
SHEET 6 HD 9 VAL H 273 LYS H 277
SHEET 7 HD 9 LEU H 247 ALA H 251 1 O LEU H 247 N ALA H 274
SHEET 8 HD 9 PHE H 219 LEU H 222 1 O PHE H 219 N LEU H 248
SHEET 9 HD 9 GLY H 318 ASN H 326 -1 O GLY H 318 N ILE H 220
SHEET 1 HE 2 LYS H 226 ILE H 227 0
SHEET 2 HE 2 ASP H 253 VAL H 254 1 O ASP H 253 N ILE H 227
SHEET 1 HF 2 TYR H 476 ASN H 479 0
SHEET 2 HF 2 GLU H 484 ASN H 487 -1 O GLU H 484 N ASN H 479
SHEET 1 IA 4 LYS I 4 PHE I 8 0
SHEET 2 IA 4 CYS I 519 ASP I 523 -1 O MET I 520 N LYS I 7
SHEET 3 IA 4 VAL J 38 LEU J 40 1 O VAL J 39 N VAL I 521
SHEET 4 IA 4 THR J 48 THR J 50 -1 O THR J 48 N LEU J 40
SHEET 1 IB 3 ILE I 175 GLU I 178 0
SHEET 2 IB 3 VAL I 376 LYS I 380 1 O ALA I 377 N THR I 176
SHEET 3 IB 3 GLU I 186 VAL I 190 -1 O GLU I 186 N LYS I 380
SHEET 1 IC10 GLY I 192 PHE I 195 0
SHEET 2 IC10 THR I 330 GLY I 335 -1 O THR I 330 N PHE I 195
SHEET 3 IC10 GLY I 318 ASN I 326 -1 N LYS I 321 O ASP I 334
SHEET 4 IC10 ALA I 212 GLU I 216 -1 O VAL I 213 N ILE I 325
SHEET 5 IC10 GLY I 318 ASN I 326 -1 O VAL I 323 N LEU I 215
SHEET 6 IC10 VAL I 273 LYS I 277
SHEET 7 IC10 LEU I 247 ALA I 251 1 O LEU I 247 N ALA I 274
SHEET 8 IC10 PHE I 219 ALA I 223 1 O PHE I 219 N LEU I 248
SHEET 9 IC10 VAL I 300 ILE I 301 1 N ILE I 301 O LEU I 222
SHEET 10 IC10 PHE I 219 ALA I 223 1 O LEU I 222 N ILE I 301
SHEET 1 ID 2 LYS I 226 ILE I 227 0
SHEET 2 ID 2 ASP I 253 VAL I 254 1 O ASP I 253 N ILE I 227
SHEET 1 IE 2 VAL I 411 ALA I 413 0
SHEET 2 IE 2 LEU I 494 PRO I 496 -1 O ASP I 495 N VAL I 412
SHEET 1 IF 2 TYR I 476 ASN I 479 0
SHEET 2 IF 2 GLU I 484 ASN I 487 -1 O GLU I 484 N ASN I 479
SHEET 1 JA 4 LYS J 4 PHE J 8 0
SHEET 2 JA 4 CYS J 519 ASP J 523 -1 O MET J 520 N LYS J 7
SHEET 3 JA 4 VAL K 38 LEU K 40 1 O VAL K 39 N VAL J 521
SHEET 4 JA 4 THR K 48 THR K 50 -1 O THR K 48 N LEU K 40
SHEET 1 JB 3 ILE J 175 ASP J 179 0
SHEET 2 JB 3 VAL J 376 VAL J 381 1 O ALA J 377 N THR J 176
SHEET 3 JB 3 GLU J 186 VAL J 190 -1 O GLU J 186 N LYS J 380
SHEET 1 JC 9 GLY J 192 PHE J 195 0
SHEET 2 JC 9 THR J 330 GLY J 335 -1 O THR J 330 N PHE J 195
SHEET 3 JC 9 GLY J 318 ASN J 326 -1 N LYS J 321 O ASP J 334
SHEET 4 JC 9 ALA J 212 GLU J 216 -1 O VAL J 213 N ILE J 325
SHEET 5 JC 9 GLY J 318 ASN J 326 -1 O VAL J 323 N LEU J 215
SHEET 6 JC 9 ALA J 274 LYS J 277
SHEET 7 JC 9 LEU J 247 ALA J 251 1 O LEU J 247 N ALA J 274
SHEET 8 JC 9 PHE J 219 LEU J 222 1 O PHE J 219 N LEU J 248
SHEET 9 JC 9 GLY J 318 ASN J 326 -1 O GLY J 318 N ILE J 220
SHEET 1 JD 2 LYS J 226 ILE J 227 0
SHEET 2 JD 2 ASP J 253 VAL J 254 1 O ASP J 253 N ILE J 227
SHEET 1 JE 2 VAL J 411 VAL J 412 0
SHEET 2 JE 2 ASP J 495 PRO J 496 -1 O ASP J 495 N VAL J 412
SHEET 1 JF 2 TYR J 476 ASN J 479 0
SHEET 2 JF 2 GLU J 484 ASN J 487 -1 O GLU J 484 N ASN J 479
SHEET 1 KA 3 LYS K 4 PHE K 8 0
SHEET 2 KA 3 CYS K 519 ASP K 523 -1 O MET K 520 N LYS K 7
SHEET 3 KA 3 VAL L 38 VAL L 39 1 O VAL L 39 N VAL K 521
SHEET 1 KB 3 VAL K 174 GLU K 178 0
SHEET 2 KB 3 VAL K 376 LYS K 380 1 O ALA K 377 N THR K 176
SHEET 3 KB 3 GLU K 186 VAL K 190 -1 O GLU K 186 N LYS K 380
SHEET 1 KC 9 GLY K 192 PHE K 195 0
SHEET 2 KC 9 THR K 330 GLY K 335 -1 O THR K 330 N PHE K 195
SHEET 3 KC 9 GLY K 318 ILE K 325 -1 N LYS K 321 O ASP K 334
SHEET 4 KC 9 VAL K 213 GLU K 216 -1 O VAL K 213 N ILE K 325
SHEET 5 KC 9 GLY K 318 ILE K 325 -1 O VAL K 323 N LEU K 215
SHEET 6 KC 9 VAL K 273 LYS K 277
SHEET 7 KC 9 LEU K 247 VAL K 254 1 O LEU K 247 N ALA K 274
SHEET 8 KC 9 PHE K 219 ILE K 227 1 O PHE K 219 N LEU K 248
SHEET 9 KC 9 GLY K 318 ILE K 325 -1 O GLY K 318 N ILE K 220
SHEET 1 KD 2 VAL K 411 VAL K 412 0
SHEET 2 KD 2 ASP K 495 PRO K 496 -1 O ASP K 495 N VAL K 412
SHEET 1 KE 2 TYR K 476 ASN K 479 0
SHEET 2 KE 2 GLU K 484 ASN K 487 -1 O GLU K 484 N ASN K 479
SHEET 1 LA 4 LYS L 4 PHE L 8 0
SHEET 2 LA 4 THR L 517 ASP L 523 -1 O MET L 520 N LYS L 7
SHEET 3 LA 4 ASN M 37 LEU M 40 1 O ASN M 37 N GLU L 518
SHEET 4 LA 4 THR M 48 THR M 50 -1 O THR M 48 N LEU M 40
SHEET 1 LB 3 VAL L 174 GLU L 178 0
SHEET 2 LB 3 VAL L 376 LYS L 380 1 O ALA L 377 N THR L 176
SHEET 3 LB 3 GLU L 186 VAL L 190 -1 O GLU L 186 N LYS L 380
SHEET 1 LC 9 GLY L 192 PHE L 195 0
SHEET 2 LC 9 THR L 329 GLY L 335 -1 O THR L 330 N PHE L 195
SHEET 3 LC 9 GLY L 318 ASN L 326 -1 N LYS L 321 O ASP L 334
SHEET 4 LC 9 VAL L 213 GLU L 216 -1 O VAL L 213 N ILE L 325
SHEET 5 LC 9 GLY L 318 ASN L 326 -1 O VAL L 323 N LEU L 215
SHEET 6 LC 9 ALA L 274 LYS L 277
SHEET 7 LC 9 LEU L 247 ALA L 251 1 O LEU L 247 N ALA L 274
SHEET 8 LC 9 PHE L 219 LEU L 222 1 O PHE L 219 N LEU L 248
SHEET 9 LC 9 GLY L 318 ASN L 326 -1 O GLY L 318 N ILE L 220
SHEET 1 LD 2 LYS L 226 ILE L 227 0
SHEET 2 LD 2 ASP L 253 VAL L 254 1 O ASP L 253 N ILE L 227
SHEET 1 LE 2 VAL L 411 ALA L 413 0
SHEET 2 LE 2 LEU L 494 PRO L 496 -1 O ASP L 495 N VAL L 412
SHEET 1 LF 2 TYR L 476 TYR L 478 0
SHEET 2 LF 2 TYR L 485 ASN L 487 -1 O GLY L 486 N GLY L 477
SHEET 1 MA 4 LYS M 4 PHE M 8 0
SHEET 2 MA 4 CYS M 519 ASP M 523 -1 O MET M 520 N LYS M 7
SHEET 3 MA 4 VAL N 38 LEU N 40 1 O VAL N 39 N VAL M 521
SHEET 4 MA 4 THR N 48 THR N 50 -1 O THR N 48 N LEU N 40
SHEET 1 MB 3 THR M 176 ASP M 179 0
SHEET 2 MB 3 VAL M 376 VAL M 381 1 O ALA M 377 N THR M 176
SHEET 3 MB 3 GLU M 186 VAL M 190 -1 O GLU M 186 N LYS M 380
SHEET 1 MC 9 GLY M 192 PHE M 195 0
SHEET 2 MC 9 THR M 330 GLY M 335 -1 O THR M 330 N PHE M 195
SHEET 3 MC 9 GLY M 318 ASN M 326 -1 N LYS M 321 O ASP M 334
SHEET 4 MC 9 ALA M 212 GLU M 216 -1 O VAL M 213 N ILE M 325
SHEET 5 MC 9 GLY M 318 ASN M 326 -1 O VAL M 323 N LEU M 215
SHEET 6 MC 9 ALA M 274 LYS M 277
SHEET 7 MC 9 LEU M 247 ALA M 251 1 O LEU M 247 N ALA M 274
SHEET 8 MC 9 PHE M 219 ALA M 223 1 O PHE M 219 N LEU M 248
SHEET 9 MC 9 GLY M 318 ASN M 326 -1 O GLY M 318 N ILE M 220
SHEET 1 MD 2 VAL M 411 ALA M 413 0
SHEET 2 MD 2 LEU M 494 PRO M 496 -1 O ASP M 495 N VAL M 412
SHEET 1 ME 2 TYR M 476 ASN M 479 0
SHEET 2 ME 2 GLU M 484 ASN M 487 -1 O GLU M 484 N ASN M 479
SHEET 1 NA 3 THR N 176 ASP N 179 0
SHEET 2 NA 3 VAL N 376 VAL N 381 1 O ALA N 377 N THR N 176
SHEET 3 NA 3 GLU N 186 VAL N 190 -1 O GLU N 186 N LYS N 380
SHEET 1 NB 9 GLY N 192 PHE N 195 0
SHEET 2 NB 9 THR N 330 GLY N 335 -1 O THR N 330 N PHE N 195
SHEET 3 NB 9 GLY N 318 ASN N 326 -1 N LYS N 321 O ASP N 334
SHEET 4 NB 9 ALA N 212 GLU N 216 -1 O VAL N 213 N ILE N 325
SHEET 5 NB 9 GLY N 318 ASN N 326 -1 O VAL N 323 N LEU N 215
SHEET 6 NB 9 VAL N 273 LYS N 277
SHEET 7 NB 9 LEU N 247 ALA N 251 1 O LEU N 247 N ALA N 274
SHEET 8 NB 9 PHE N 219 LEU N 222 1 O PHE N 219 N LEU N 248
SHEET 9 NB 9 GLY N 318 ASN N 326 -1 O GLY N 318 N ILE N 220
SHEET 1 NC 2 VAL N 412 ALA N 413 0
SHEET 2 NC 2 LEU N 494 ASP N 495 -1 O ASP N 495 N VAL N 412
SHEET 1 ND 2 TYR N 476 ASN N 479 0
SHEET 2 ND 2 GLU N 484 ASN N 487 -1 O GLU N 484 N ASN N 479
SHEET 1 OA 3 ARG O 4 PRO O 5 0
SHEET 2 OA 3 ILE P 91 ILE P 94 -1 O ILE P 94 N ARG O 4
SHEET 3 OA 3 ILE P 66 PHE P 67 -1 O ILE P 66 N LEU P 92
SHEET 1 OB 7 LYS O 74 ILE O 78 0
SHEET 2 OB 7 GLU O 81 SER O 87 -1 O GLU O 81 N ILE O 78
SHEET 3 OB 7 ARG O 9 ARG O 14 -1 O VAL O 10 N MET O 86
SHEET 4 OB 7 ARG O 37 VAL O 43 -1 O GLU O 39 N LYS O 13
SHEET 5 OB 7 ILE O 64 PHE O 67 -1 O VAL O 65 N GLY O 38
SHEET 6 OB 7 ILE O 91 ILE O 94 -1 N LEU O 92 O ILE O 66
SHEET 7 OB 7 ARG U 4 PRO U 5 -1 O ARG U 4 N ILE O 94
SHEET 1 PA 7 ARG P 4 PRO P 5 0
SHEET 2 PA 7 ILE Q 91 ILE Q 94 -1 O ILE Q 94 N ARG P 4
SHEET 3 PA 7 ILE Q 64 PHE Q 67 -1 O ILE Q 66 N LEU Q 92
SHEET 4 PA 7 ARG Q 37 VAL Q 43 -1 O GLY Q 38 N VAL Q 65
SHEET 5 PA 7 ARG Q 9 ARG Q 14 -1 O ILE Q 11 N LEU Q 41
SHEET 6 PA 7 GLU Q 81 SER Q 87 -1 O LEU Q 84 N VAL Q 12
SHEET 7 PA 7 LYS Q 74 ILE Q 78 -1 O LYS Q 74 N ILE Q 85
SHEET 1 PB 4 GLY P 38 VAL P 43 0
SHEET 2 PB 4 ARG P 9 ARG P 14 -1 O ILE P 11 N ALA P 42
SHEET 3 PB 4 VAL P 83 SER P 87 -1 O LEU P 84 N VAL P 12
SHEET 4 PB 4 LYS P 74 GLU P 76 -1 O LYS P 74 N ILE P 85
SHEET 1 QA 7 ARG Q 4 PRO Q 5 0
SHEET 2 QA 7 ILE R 91 ILE R 94 -1 O ILE R 94 N ARG Q 4
SHEET 3 QA 7 ILE R 64 PHE R 67 -1 O ILE R 66 N LEU R 92
SHEET 4 QA 7 ARG R 37 VAL R 43 -1 O GLY R 38 N VAL R 65
SHEET 5 QA 7 ARG R 9 ARG R 14 -1 O ILE R 11 N LEU R 41
SHEET 6 QA 7 GLU R 81 SER R 87 -1 O LEU R 84 N VAL R 12
SHEET 7 QA 7 VAL R 73 ILE R 78 -1 O LYS R 74 N ILE R 85
SHEET 1 RA 7 ARG R 4 PRO R 5 0
SHEET 2 RA 7 ILE S 91 ILE S 94 -1 O ILE S 94 N ARG R 4
SHEET 3 RA 7 ILE S 64 PHE S 67 -1 O ILE S 66 N LEU S 92
SHEET 4 RA 7 ARG S 37 VAL S 43 -1 O GLY S 38 N VAL S 65
SHEET 5 RA 7 ARG S 9 ARG S 14 -1 O ILE S 11 N LEU S 41
SHEET 6 RA 7 GLU S 81 SER S 87 -1 O LEU S 84 N VAL S 12
SHEET 7 RA 7 LYS S 74 ILE S 78 -1 O LYS S 74 N ILE S 85
SHEET 1 SA 7 ARG S 4 PRO S 5 0
SHEET 2 SA 7 ILE T 91 ILE T 94 -1 O ILE T 94 N ARG S 4
SHEET 3 SA 7 ILE T 64 PHE T 67 -1 O ILE T 66 N LEU T 92
SHEET 4 SA 7 ARG T 37 ALA T 42 -1 O GLY T 38 N VAL T 65
SHEET 5 SA 7 VAL T 10 ARG T 14 -1 O ILE T 11 N LEU T 41
SHEET 6 SA 7 GLU T 81 MET T 86 -1 O LEU T 84 N VAL T 12
SHEET 7 SA 7 LYS T 74 ILE T 78 -1 O LYS T 74 N ILE T 85
SHEET 1 TA 7 ARG T 4 PRO T 5 0
SHEET 2 TA 7 ILE U 91 ILE U 94 -1 O ILE U 94 N ARG T 4
SHEET 3 TA 7 ILE U 64 PHE U 67 -1 O ILE U 66 N LEU U 92
SHEET 4 TA 7 ARG U 37 ALA U 42 -1 O GLY U 38 N VAL U 65
SHEET 5 TA 7 ARG U 9 ARG U 14 -1 O ILE U 11 N ALA U 42
SHEET 6 TA 7 GLU U 81 SER U 87 -1 O GLU U 82 N ARG U 14
SHEET 7 TA 7 LYS U 74 ILE U 78 -1 O LYS U 74 N ILE U 85
CRYST1 268.800 268.800 268.800 90.00 90.00 90.00 P 1 14
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 0.003720 0.000000 0.000000 0.00000
SCALE2 0.000000 0.003720 0.000000 0.00000
SCALE3 0.000000 0.000000 0.003720 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
