HEADER RIBOSOME 07-JAN-11 3IZU
TITLE STRUCTURAL INSIGHTS INTO COGNATE VS. NEAR-COGNATE DISCRIMINATION
TITLE 2 DURING DECODING. THIS ENTRY CONTAINS THE LARGE SUBUNIT OF A RIBOSOME
TITLE 3 PROGRAMMED WITH A COGNATE CODON
SPLIT 3IZU 3IZW
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: RIBOSOMAL RNA 5S;
COMPND 3 CHAIN: A;
COMPND 4 MOL_ID: 2;
COMPND 5 MOLECULE: RIBOSOMAL RNA 23S;
COMPND 6 CHAIN: B;
COMPND 7 MOL_ID: 3;
COMPND 8 MOLECULE: 50S RIBOSOMAL PROTEIN L1;
COMPND 9 CHAIN: C;
COMPND 10 MOL_ID: 4;
COMPND 11 MOLECULE: 50S RIBOSOMAL PROTEIN L2;
COMPND 12 CHAIN: D;
COMPND 13 MOL_ID: 5;
COMPND 14 MOLECULE: 50S RIBOSOMAL PROTEIN L3;
COMPND 15 CHAIN: E;
COMPND 16 MOL_ID: 6;
COMPND 17 MOLECULE: 50S RIBOSOMAL PROTEIN L4;
COMPND 18 CHAIN: F;
COMPND 19 MOL_ID: 7;
COMPND 20 MOLECULE: 50S RIBOSOMAL PROTEIN L5;
COMPND 21 CHAIN: G;
COMPND 22 MOL_ID: 8;
COMPND 23 MOLECULE: 50S RIBOSOMAL PROTEIN L6;
COMPND 24 CHAIN: H;
COMPND 25 MOL_ID: 9;
COMPND 26 MOLECULE: 50S RIBOSOMAL PROTEIN L9;
COMPND 27 CHAIN: I;
COMPND 28 MOL_ID: 10;
COMPND 29 MOLECULE: 50S RIBOSOMAL PROTEIN L11;
COMPND 30 CHAIN: J;
COMPND 31 MOL_ID: 11;
COMPND 32 MOLECULE: 50S RIBOSOMAL PROTEIN L13;
COMPND 33 CHAIN: K;
COMPND 34 MOL_ID: 12;
COMPND 35 MOLECULE: 50S RIBOSOMAL PROTEIN L14;
COMPND 36 CHAIN: L;
COMPND 37 MOL_ID: 13;
COMPND 38 MOLECULE: 50S RIBOSOMAL PROTEIN L15;
COMPND 39 CHAIN: M;
COMPND 40 MOL_ID: 14;
COMPND 41 MOLECULE: 50S RIBOSOMAL PROTEIN L16;
COMPND 42 CHAIN: N;
COMPND 43 MOL_ID: 15;
COMPND 44 MOLECULE: 50S RIBOSOMAL PROTEIN L17;
COMPND 45 CHAIN: O;
COMPND 46 MOL_ID: 16;
COMPND 47 MOLECULE: 50S RIBOSOMAL PROTEIN L18;
COMPND 48 CHAIN: P;
COMPND 49 MOL_ID: 17;
COMPND 50 MOLECULE: 50S RIBOSOMAL PROTEIN L19;
COMPND 51 CHAIN: Q;
COMPND 52 MOL_ID: 18;
COMPND 53 MOLECULE: 50S RIBOSOMAL PROTEIN L20;
COMPND 54 CHAIN: R;
COMPND 55 MOL_ID: 19;
COMPND 56 MOLECULE: 50S RIBOSOMAL PROTEIN L21;
COMPND 57 CHAIN: S;
COMPND 58 MOL_ID: 20;
COMPND 59 MOLECULE: 50S RIBOSOMAL PROTEIN L22;
COMPND 60 CHAIN: T;
COMPND 61 MOL_ID: 21;
COMPND 62 MOLECULE: 50S RIBOSOMAL PROTEIN L23;
COMPND 63 CHAIN: U;
COMPND 64 MOL_ID: 22;
COMPND 65 MOLECULE: 50S RIBOSOMAL PROTEIN L24;
COMPND 66 CHAIN: V;
COMPND 67 MOL_ID: 23;
COMPND 68 MOLECULE: 50S RIBOSOMAL PROTEIN L25;
COMPND 69 CHAIN: W;
COMPND 70 MOL_ID: 24;
COMPND 71 MOLECULE: 50S RIBOSOMAL PROTEIN L27;
COMPND 72 CHAIN: X;
COMPND 73 MOL_ID: 25;
COMPND 74 MOLECULE: 50S RIBOSOMAL PROTEIN L28;
COMPND 75 CHAIN: Y;
COMPND 76 MOL_ID: 26;
COMPND 77 MOLECULE: 50S RIBOSOMAL PROTEIN L29;
COMPND 78 CHAIN: Z;
COMPND 79 MOL_ID: 27;
COMPND 80 MOLECULE: 50S RIBOSOMAL PROTEIN L30;
COMPND 81 CHAIN: a;
COMPND 82 MOL_ID: 28;
COMPND 83 MOLECULE: 50S RIBOSOMAL PROTEIN L31;
COMPND 84 CHAIN: b;
COMPND 85 MOL_ID: 29;
COMPND 86 MOLECULE: 50S RIBOSOMAL PROTEIN L32;
COMPND 87 CHAIN: c;
COMPND 88 MOL_ID: 30;
COMPND 89 MOLECULE: 50S RIBOSOMAL PROTEIN L33;
COMPND 90 CHAIN: d;
COMPND 91 MOL_ID: 31;
COMPND 92 MOLECULE: 50S RIBOSOMAL PROTEIN L34;
COMPND 93 CHAIN: e;
COMPND 94 MOL_ID: 32;
COMPND 95 MOLECULE: 50S RIBOSOMAL PROTEIN L35;
COMPND 96 CHAIN: f;
COMPND 97 MOL_ID: 33;
COMPND 98 MOLECULE: 50S RIBOSOMAL PROTEIN L36;
COMPND 99 CHAIN: g
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 3 ORGANISM_TAXID: 83333;
SOURCE 4 STRAIN: K12;
SOURCE 5 MOL_ID: 2;
SOURCE 6 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 7 ORGANISM_TAXID: 83333;
SOURCE 8 STRAIN: K12;
SOURCE 9 MOL_ID: 3;
SOURCE 10 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 11 ORGANISM_TAXID: 83333;
SOURCE 12 STRAIN: K12;
SOURCE 13 MOL_ID: 4;
SOURCE 14 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 15 ORGANISM_TAXID: 83333;
SOURCE 16 STRAIN: K12;
SOURCE 17 MOL_ID: 5;
SOURCE 18 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 19 ORGANISM_TAXID: 83333;
SOURCE 20 STRAIN: K12;
SOURCE 21 MOL_ID: 6;
SOURCE 22 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 23 ORGANISM_TAXID: 83333;
SOURCE 24 STRAIN: K12;
SOURCE 25 MOL_ID: 7;
SOURCE 26 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 27 ORGANISM_TAXID: 83333;
SOURCE 28 STRAIN: K12;
SOURCE 29 MOL_ID: 8;
SOURCE 30 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 31 ORGANISM_TAXID: 83333;
SOURCE 32 STRAIN: K12;
SOURCE 33 MOL_ID: 9;
SOURCE 34 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 35 ORGANISM_TAXID: 83333;
SOURCE 36 STRAIN: K12;
SOURCE 37 MOL_ID: 10;
SOURCE 38 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 39 ORGANISM_TAXID: 83333;
SOURCE 40 STRAIN: K12;
SOURCE 41 MOL_ID: 11;
SOURCE 42 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 43 ORGANISM_TAXID: 83333;
SOURCE 44 STRAIN: K12;
SOURCE 45 MOL_ID: 12;
SOURCE 46 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 47 ORGANISM_TAXID: 83333;
SOURCE 48 STRAIN: K12;
SOURCE 49 MOL_ID: 13;
SOURCE 50 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 51 ORGANISM_TAXID: 83333;
SOURCE 52 STRAIN: K12;
SOURCE 53 MOL_ID: 14;
SOURCE 54 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 55 ORGANISM_TAXID: 83333;
SOURCE 56 STRAIN: K12;
SOURCE 57 MOL_ID: 15;
SOURCE 58 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 59 ORGANISM_TAXID: 83333;
SOURCE 60 STRAIN: K12;
SOURCE 61 MOL_ID: 16;
SOURCE 62 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 63 ORGANISM_TAXID: 83333;
SOURCE 64 STRAIN: K12;
SOURCE 65 MOL_ID: 17;
SOURCE 66 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 67 ORGANISM_TAXID: 83333;
SOURCE 68 STRAIN: K12;
SOURCE 69 MOL_ID: 18;
SOURCE 70 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 71 ORGANISM_TAXID: 83333;
SOURCE 72 STRAIN: K12;
SOURCE 73 MOL_ID: 19;
SOURCE 74 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 75 ORGANISM_TAXID: 83333;
SOURCE 76 STRAIN: K12;
SOURCE 77 MOL_ID: 20;
SOURCE 78 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 79 ORGANISM_TAXID: 83333;
SOURCE 80 STRAIN: K12;
SOURCE 81 MOL_ID: 21;
SOURCE 82 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 83 ORGANISM_TAXID: 83333;
SOURCE 84 STRAIN: K12;
SOURCE 85 MOL_ID: 22;
SOURCE 86 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 87 ORGANISM_TAXID: 83333;
SOURCE 88 STRAIN: K12;
SOURCE 89 MOL_ID: 23;
SOURCE 90 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 91 ORGANISM_TAXID: 83333;
SOURCE 92 STRAIN: K12;
SOURCE 93 MOL_ID: 24;
SOURCE 94 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 95 ORGANISM_TAXID: 83333;
SOURCE 96 STRAIN: K12;
SOURCE 97 MOL_ID: 25;
SOURCE 98 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 99 ORGANISM_TAXID: 83333;
SOURCE 100 STRAIN: K12;
SOURCE 101 MOL_ID: 26;
SOURCE 102 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 103 ORGANISM_TAXID: 83333;
SOURCE 104 STRAIN: K12;
SOURCE 105 MOL_ID: 27;
SOURCE 106 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 107 ORGANISM_TAXID: 83333;
SOURCE 108 STRAIN: K12;
SOURCE 109 MOL_ID: 28;
SOURCE 110 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 111 ORGANISM_TAXID: 83333;
SOURCE 112 STRAIN: K12;
SOURCE 113 MOL_ID: 29;
SOURCE 114 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 115 ORGANISM_TAXID: 83333;
SOURCE 116 STRAIN: K12;
SOURCE 117 MOL_ID: 30;
SOURCE 118 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 119 ORGANISM_TAXID: 83333;
SOURCE 120 STRAIN: K12;
SOURCE 121 MOL_ID: 31;
SOURCE 122 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 123 ORGANISM_TAXID: 83333;
SOURCE 124 STRAIN: K12;
SOURCE 125 MOL_ID: 32;
SOURCE 126 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 127 ORGANISM_TAXID: 83333;
SOURCE 128 STRAIN: K12;
SOURCE 129 MOL_ID: 33;
SOURCE 130 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 131 ORGANISM_TAXID: 83333;
SOURCE 132 STRAIN: K12
KEYWDS TRANSLATION, RIBOSOME, TERNARY COMPLEX, TRNA INCORPORATION, CRYOEM,
KEYWDS 2 NEAR-COGNATE
EXPDTA ELECTRON MICROSCOPY
AUTHOR X.AGIRREZABALA,E.SCHREINER,L.G.TRABUCO,J.LEI,R.F.ORTIZ-MEOZ,
AUTHOR 2 K.SCHULTEN,R.GREEN,J.FRANK
REVDAT 4 30-MAY-12 3IZU 1 REMARK
REVDAT 3 01-FEB-12 3IZU 1 MODRES CRYST1 LINK REMARK
REVDAT 2 04-MAY-11 3IZU 1 JRNL
REVDAT 1 23-MAR-11 3IZU 0
JRNL AUTH X.AGIRREZABALA,E.SCHREINER,L.G.TRABUCO,J.LEI,R.F.ORTIZ-MEOZ,
JRNL AUTH 2 K.SCHULTEN,R.GREEN,J.FRANK
JRNL TITL STRUCTURAL INSIGHTS INTO COGNATE VERSUS NEAR-COGNATE
JRNL TITL 2 DISCRIMINATION DURING DECODING.
JRNL REF EMBO J. V. 30 1497 2011
JRNL REFN ISSN 0261-4189
JRNL PMID 21378755
JRNL DOI 10.1038/EMBOJ.2011.58
REMARK 2
REMARK 2 RESOLUTION. 8.25 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : NAMD 2.7
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : 2I2V
REMARK 3 REFINEMENT SPACE : REAL
REMARK 3 REFINEMENT PROTOCOL : NULL
REMARK 3 REFINEMENT TARGET : RMSD < 0.1 A/NS
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : FLEXIBLE FITTING, MDFF
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 8.250
REMARK 3 NUMBER OF PARTICLES : NULL
REMARK 3 CTF CORRECTION METHOD : NULL
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 3IZU COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 18-JAN-11.
REMARK 100 THE RCSB ID CODE IS RCSB160072.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : VITREOUS ICE (CRYO EM)
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : ASYMMETRIC
REMARK 245 NAME OF SAMPLE : NULL
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : NULL
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : NULL
REMARK 245 DETECTOR TYPE : NULL
REMARK 245 MINIMUM DEFOCUS (NM) : NULL
REMARK 245 MAXIMUM DEFOCUS (NM) : NULL
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : NULL
REMARK 245 IMAGING MODE : NULL
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : NULL
REMARK 245 ILLUMINATION MODE : NULL
REMARK 245 NOMINAL MAGNIFICATION : NULL
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : NULL
REMARK 245 ACCELERATION VOLTAGE (KV) : NULL
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1
REMARK 290
REMARK 290 SYMOP SYMMETRY
REMARK 290 NNNMMM OPERATOR
REMARK 290 1555 X,Y,Z
REMARK 290
REMARK 290 WHERE NNN -> OPERATOR NUMBER
REMARK 290 MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000
REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 33-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H, I,
REMARK 350 AND CHAINS: J, K, L, M, N, O, P, Q, R,
REMARK 350 AND CHAINS: S, T, U, V, W, X, Y, Z, a,
REMARK 350 AND CHAINS: b, c, d, e, f, g
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET D 0
REMARK 465 MET G 0
REMARK 465 MET H 0
REMARK 465 MET J 0
REMARK 465 MET Q 0
REMARK 465 MET R 0
REMARK 465 MET V 0
REMARK 465 MET X 0
REMARK 465 MET Y 0
REMARK 465 MET a 0
REMARK 465 MET c 0
REMARK 465 MET d 0
REMARK 465 MET f 0
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 U A 1 O4' - C1' - N1 ANGL. DEV. = 4.8 DEGREES
REMARK 500 C A 3 C5' - C4' - O4' ANGL. DEV. = 5.7 DEGREES
REMARK 500 C A 4 O4' - C1' - N1 ANGL. DEV. = 4.7 DEGREES
REMARK 500 U A 5 O4' - C1' - N1 ANGL. DEV. = 4.5 DEGREES
REMARK 500 C A 11 O4' - C1' - N1 ANGL. DEV. = 6.8 DEGREES
REMARK 500 G A 13 N9 - C1' - C2' ANGL. DEV. = -9.3 DEGREES
REMARK 500 G A 13 O4' - C1' - N9 ANGL. DEV. = 11.9 DEGREES
REMARK 500 U A 14 C5' - C4' - C3' ANGL. DEV. = -9.0 DEGREES
REMARK 500 G A 16 C8 - N9 - C4 ANGL. DEV. = -2.4 DEGREES
REMARK 500 G A 18 C5' - C4' - O4' ANGL. DEV. = 5.6 DEGREES
REMARK 500 C A 19 O4' - C1' - N1 ANGL. DEV. = 4.9 DEGREES
REMARK 500 C A 28 O4' - C1' - N1 ANGL. DEV. = 5.2 DEGREES
REMARK 500 A A 29 O4' - C1' - N9 ANGL. DEV. = 4.3 DEGREES
REMARK 500 C A 30 O4' - C1' - N1 ANGL. DEV. = 9.8 DEGREES
REMARK 500 C A 31 C5' - C4' - O4' ANGL. DEV. = 6.8 DEGREES
REMARK 500 U A 32 C3' - C2' - C1' ANGL. DEV. = -4.4 DEGREES
REMARK 500 U A 32 O4' - C1' - N1 ANGL. DEV. = 5.1 DEGREES
REMARK 500 A A 34 C5' - C4' - O4' ANGL. DEV. = 7.3 DEGREES
REMARK 500 C A 36 C5' - C4' - C3' ANGL. DEV. = -8.9 DEGREES
REMARK 500 C A 36 O4' - C1' - N1 ANGL. DEV. = 6.1 DEGREES
REMARK 500 A A 39 O4' - C1' - N9 ANGL. DEV. = 4.3 DEGREES
REMARK 500 G A 41 O4' - C1' - N9 ANGL. DEV. = 5.2 DEGREES
REMARK 500 C A 42 O4' - C1' - N1 ANGL. DEV. = 4.9 DEGREES
REMARK 500 C A 47 O4' - C1' - N1 ANGL. DEV. = 5.3 DEGREES
REMARK 500 C A 49 O4' - C1' - N1 ANGL. DEV. = 10.0 DEGREES
REMARK 500 A A 50 C5' - C4' - C3' ANGL. DEV. = -8.6 DEGREES
REMARK 500 A A 50 C5' - C4' - O4' ANGL. DEV. = 5.9 DEGREES
REMARK 500 A A 52 O4' - C1' - N9 ANGL. DEV. = 7.3 DEGREES
REMARK 500 G A 64 O4' - C1' - N9 ANGL. DEV. = 4.8 DEGREES
REMARK 500 G A 67 C5' - C4' - O4' ANGL. DEV. = 6.9 DEGREES
REMARK 500 G A 67 C8 - N9 - C4 ANGL. DEV. = -2.7 DEGREES
REMARK 500 C A 68 O4' - C1' - N1 ANGL. DEV. = 7.0 DEGREES
REMARK 500 G A 69 O4' - C1' - N9 ANGL. DEV. = 5.1 DEGREES
REMARK 500 C A 70 O4' - C1' - N1 ANGL. DEV. = 5.9 DEGREES
REMARK 500 C A 71 O4' - C1' - N1 ANGL. DEV. = 4.9 DEGREES
REMARK 500 G A 72 C5' - C4' - O4' ANGL. DEV. = 5.6 DEGREES
REMARK 500 U A 74 O4' - C1' - N1 ANGL. DEV. = 4.9 DEGREES
REMARK 500 G A 75 O5' - C5' - C4' ANGL. DEV. = -7.6 DEGREES
REMARK 500 U A 77 C5' - C4' - O4' ANGL. DEV. = 5.5 DEGREES
REMARK 500 U A 77 C2' - C3' - O3' ANGL. DEV. = 9.7 DEGREES
REMARK 500 G A 79 C8 - N9 - C4 ANGL. DEV. = -2.4 DEGREES
REMARK 500 G A 84 O4' - C1' - N9 ANGL. DEV. = 4.7 DEGREES
REMARK 500 G A 85 O4' - C1' - N9 ANGL. DEV. = 5.1 DEGREES
REMARK 500 G A 86 O4' - C1' - N9 ANGL. DEV. = 5.7 DEGREES
REMARK 500 U A 89 O4' - C1' - N1 ANGL. DEV. = 5.7 DEGREES
REMARK 500 C A 90 C1' - O4' - C4' ANGL. DEV. = -5.3 DEGREES
REMARK 500 C A 91 O4' - C1' - N1 ANGL. DEV. = 4.9 DEGREES
REMARK 500 C A 92 O4' - C1' - N1 ANGL. DEV. = 5.0 DEGREES
REMARK 500 C A 93 O4' - C1' - N1 ANGL. DEV. = 7.2 DEGREES
REMARK 500 U A 95 C5' - C4' - C3' ANGL. DEV. = -9.0 DEGREES
REMARK 500
REMARK 500 THIS ENTRY HAS 1525 ANGLE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 ASP C 16 7.70 -152.08
REMARK 500 THR C 69 -6.57 -140.84
REMARK 500 ASN C 83 92.18 -65.55
REMARK 500 MET C 97 -34.58 -147.82
REMARK 500 LEU C 131 -19.73 -149.96
REMARK 500 PRO C 140 -12.85 -49.23
REMARK 500 LYS C 141 -52.08 -128.22
REMARK 500 ASN C 148 63.48 -102.41
REMARK 500 ASP C 166 -52.95 -138.66
REMARK 500 THR C 217 -86.34 -61.32
REMARK 500 LEU C 229 26.20 -61.16
REMARK 500 SER C 230 18.96 -151.18
REMARK 500 PRO D 7 42.30 -86.26
REMARK 500 ASN D 36 61.42 -161.11
REMARK 500 ILE D 63 90.77 -66.21
REMARK 500 VAL D 119 13.30 -59.39
REMARK 500 PRO D 125 115.36 -35.35
REMARK 500 VAL D 140 -131.63 51.13
REMARK 500 HIS D 141 -53.76 -161.43
REMARK 500 ALA D 154 73.47 46.27
REMARK 500 ALA D 169 2.90 -67.33
REMARK 500 THR D 190 -171.10 51.56
REMARK 500 GLU D 193 158.50 57.77
REMARK 500 ARG D 237 -19.09 56.78
REMARK 500 LYS D 252 53.40 -152.47
REMARK 500 SER D 258 15.13 -151.08
REMARK 500 LYS D 260 4.64 47.25
REMARK 500 ALA E 31 97.51 -68.19
REMARK 500 ASN E 32 51.18 -93.57
REMARK 500 ALA E 41 -0.53 -166.60
REMARK 500 ASP E 43 25.48 36.12
REMARK 500 ALA E 57 19.70 56.00
REMARK 500 GLU E 88 -39.49 -144.03
REMARK 500 SER E 113 -175.31 62.75
REMARK 500 VAL E 122 -2.57 38.36
REMARK 500 ARG E 124 -8.92 -152.86
REMARK 500 SER E 137 100.07 -43.74
REMARK 500 GLN E 150 -62.25 31.24
REMARK 500 LYS E 157 109.55 -52.08
REMARK 500 ALA E 162 167.74 69.80
REMARK 500 ASN E 167 15.95 -146.49
REMARK 500 ARG E 169 -99.00 -151.26
REMARK 500 VAL E 170 143.00 58.63
REMARK 500 GLU E 183 -29.88 73.89
REMARK 500 ALA F 39 5.79 -67.20
REMARK 500 GLN F 41 -33.84 -135.33
REMARK 500 LYS F 57 157.82 -49.15
REMARK 500 GLN F 62 141.89 63.10
REMARK 500 THR F 65 -57.83 -151.17
REMARK 500 ARG F 79 98.62 -60.25
REMARK 500
REMARK 500 THIS ENTRY HAS 208 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 ASP C 43 VAL C 44 148.15
REMARK 500 VAL C 44 ALA C 45 149.46
REMARK 500 ALA E 47 ILE E 48 148.15
REMARK 500 ILE F 77 TRP F 78 147.03
REMARK 500 ALA H 39 VAL H 40 -149.94
REMARK 500 GLY H 107 PHE H 108 147.28
REMARK 500 LEU I 117 PRO I 118 145.75
REMARK 500 GLY K 51 ASP K 52 -149.13
REMARK 500 LYS R 4 ARG R 5 -143.40
REMARK 500 GLN e 6 PRO e 7 -147.10
REMARK 500 SER e 45 LYS e 46 149.12
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: PLANAR GROUPS
REMARK 500
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS
REMARK 500 AN RMSD GREATER THAN THIS VALUE
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 M RES CSSEQI RMS TYPE
REMARK 500 G A 2 0.08 SIDE CHAIN
REMARK 500 G A 7 0.05 SIDE CHAIN
REMARK 500 G A 13 0.12 SIDE CHAIN
REMARK 500 U A 14 0.10 SIDE CHAIN
REMARK 500 A A 15 0.06 SIDE CHAIN
REMARK 500 C A 19 0.09 SIDE CHAIN
REMARK 500 C A 26 0.12 SIDE CHAIN
REMARK 500 C A 36 0.11 SIDE CHAIN
REMARK 500 C A 37 0.07 SIDE CHAIN
REMARK 500 U A 40 0.12 SIDE CHAIN
REMARK 500 G A 41 0.05 SIDE CHAIN
REMARK 500 U A 48 0.08 SIDE CHAIN
REMARK 500 A A 52 0.13 SIDE CHAIN
REMARK 500 C A 62 0.06 SIDE CHAIN
REMARK 500 G A 64 0.06 SIDE CHAIN
REMARK 500 U A 65 0.08 SIDE CHAIN
REMARK 500 A A 66 0.06 SIDE CHAIN
REMARK 500 G A 67 0.07 SIDE CHAIN
REMARK 500 G A 72 0.07 SIDE CHAIN
REMARK 500 U A 87 0.10 SIDE CHAIN
REMARK 500 C A 88 0.09 SIDE CHAIN
REMARK 500 U A 95 0.08 SIDE CHAIN
REMARK 500 A A 99 0.06 SIDE CHAIN
REMARK 500 U A 103 0.09 SIDE CHAIN
REMARK 500 G A 107 0.07 SIDE CHAIN
REMARK 500 A A 108 0.07 SIDE CHAIN
REMARK 500 A A 109 0.08 SIDE CHAIN
REMARK 500 G B 7 0.06 SIDE CHAIN
REMARK 500 G B 17 0.08 SIDE CHAIN
REMARK 500 C B 20 0.06 SIDE CHAIN
REMARK 500 C B 22 0.07 SIDE CHAIN
REMARK 500 G B 23 0.07 SIDE CHAIN
REMARK 500 G B 24 0.09 SIDE CHAIN
REMARK 500 U B 29 0.07 SIDE CHAIN
REMARK 500 C B 32 0.06 SIDE CHAIN
REMARK 500 C B 33 0.08 SIDE CHAIN
REMARK 500 U B 34 0.07 SIDE CHAIN
REMARK 500 G B 45 0.07 SIDE CHAIN
REMARK 500 C B 47 0.06 SIDE CHAIN
REMARK 500 G B 60 0.07 SIDE CHAIN
REMARK 500 U B 62 0.12 SIDE CHAIN
REMARK 500 U B 65 0.08 SIDE CHAIN
REMARK 500 G B 68 0.07 SIDE CHAIN
REMARK 500 A B 71 0.07 SIDE CHAIN
REMARK 500 U B 72 0.07 SIDE CHAIN
REMARK 500 A B 74 0.07 SIDE CHAIN
REMARK 500 G B 77 0.05 SIDE CHAIN
REMARK 500 G B 81 0.07 SIDE CHAIN
REMARK 500 A B 83 0.12 SIDE CHAIN
REMARK 500 G B 88 0.05 SIDE CHAIN
REMARK 500
REMARK 500 THIS ENTRY HAS 852 PLANE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: MAIN CHAIN PLANARITY
REMARK 500
REMARK 500 THE FOLLOWING RESIDUES HAVE A PSEUDO PLANARITY
REMARK 500 TORSION ANGLE, C(I) - CA(I) - N(I+1) - O(I), GREATER
REMARK 500 10.0 DEGREES. (M=MODEL NUMBER; RES=RESIDUE NAME;
REMARK 500 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 500 I=INSERTION CODE).
REMARK 500
REMARK 500 M RES CSSEQI ANGLE
REMARK 500 VAL E 24 -11.04
REMARK 500 ALA E 47 -10.23
REMARK 500 VAL I 31 -12.78
REMARK 500 GLY b 54 -10.50
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CHIRAL CENTERS
REMARK 500
REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL
REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY
REMARK 500 FOR AMINO ACIDS AND C1'--O4'--N1(N9)--C2' FOR
REMARK 500 NUCLEIC ACIDS OR EQUIVALENT ANGLE
REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16)
REMARK 500
REMARK 500 M RES CSSEQI IMPROPER EXPECTED FOUND DETAILS
REMARK 500 VAL C 73 24.2 L L OUTSIDE RANGE
REMARK 500 PHE O 80 24.7 L L OUTSIDE RANGE
REMARK 500 ILE X 36 24.1 L L OUTSIDE RANGE
REMARK 500 VAL Z 46 24.8 L L OUTSIDE RANGE
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-1849 RELATED DB: EMDB
REMARK 900 CRYO-EM MAP OF E. COLI RIBOSOME PROGRAMMED WITH COGNATE
REMARK 900 CODON
DBREF1 3IZU A 1 120 GB AP012030.1
DBREF2 3IZU A AP012030 228757 228876
DBREF1 3IZU B 1 2904 GB AP012030.1
DBREF2 3IZU B AP012030 4147746 4150649
DBREF 3IZU C 1 234 UNP P0A7L0 RL1_ECOLI 1 234
DBREF 3IZU D 0 272 UNP P60422 RL2_ECOLI 1 273
DBREF 3IZU E 1 209 UNP P60438 RL3_ECOLI 1 209
DBREF 3IZU F 1 201 UNP P60723 RL4_ECOLI 1 201
DBREF 3IZU G 0 178 UNP P62399 RL5_ECOLI 1 179
DBREF 3IZU H 0 176 UNP P0AG55 RL6_ECOLI 1 177
DBREF 3IZU I 1 149 UNP P0A7R1 RL9_ECOLI 1 149
DBREF 3IZU J 0 141 UNP P0A7J7 RL11_ECOLI 1 142
DBREF 3IZU K 1 142 UNP P0AA10 RL13_ECOLI 1 142
DBREF 3IZU L 1 123 UNP P0ADY3 RL14_ECOLI 1 123
DBREF 3IZU M 1 144 UNP P02413 RL15_ECOLI 1 144
DBREF 3IZU N 1 136 UNP P0ADY7 RL16_ECOLI 1 136
DBREF 3IZU O 1 127 UNP P0AG44 RL17_ECOLI 1 127
DBREF 3IZU P 1 117 UNP P0C018 RL18_ECOLI 1 117
DBREF 3IZU Q 0 114 UNP P0A7K6 RL19_ECOLI 1 115
DBREF 3IZU R 0 117 UNP P0A7L3 RL20_ECOLI 1 118
DBREF 3IZU S 1 103 UNP P0AG48 RL21_ECOLI 1 103
DBREF 3IZU T 1 110 UNP P61175 RL22_ECOLI 1 110
DBREF 3IZU U 1 100 UNP P0ADZ0 RL23_ECOLI 1 100
DBREF 3IZU V 0 103 UNP P60624 RL24_ECOLI 1 104
DBREF 3IZU W 1 94 UNP P68919 RL25_ECOLI 1 94
DBREF 3IZU X 0 84 UNP P0A7L8 RL27_ECOLI 1 85
DBREF 3IZU Y 0 77 UNP P0A7M2 RL28_ECOLI 1 78
DBREF 3IZU Z 1 63 UNP P0A7M6 RL29_ECOLI 1 63
DBREF 3IZU a 0 58 UNP P0AG51 RL30_ECOLI 1 59
DBREF 3IZU b 1 70 UNP P0A7M9 RL31_ECOLI 1 70
DBREF 3IZU c 0 56 UNP P0A7N4 RL32_ECOLI 1 57
DBREF 3IZU d 0 54 UNP P0A7N9 RL33_ECOLI 1 55
DBREF 3IZU e 1 46 UNP P0A7P5 RL34_ECOLI 1 46
DBREF 3IZU f 0 64 UNP P0A7Q1 RL35_ECOLI 1 65
DBREF 3IZU g 1 38 GB P0A7Q6 P0A7Q6 1 38
SEQRES 1 A 120 U G C C U G G C G G C C G
SEQRES 2 A 120 U A G C G C G G U G G U C
SEQRES 3 A 120 C C A C C U G A C C C C A
SEQRES 4 A 120 U G C C G A A C U C A G A
SEQRES 5 A 120 A G U G A A A C G C C G U
SEQRES 6 A 120 A G C G C C G A U G G U A
SEQRES 7 A 120 G U G U G G G G U C U C C
SEQRES 8 A 120 C C A U G C G A G A G U A
SEQRES 9 A 120 G G G A A C U G C C A G G
SEQRES 10 A 120 C A U
SEQRES 1 B 2904 G G U U A A G C G A C U A
SEQRES 2 B 2904 A G C G U A C A C G G U G
SEQRES 3 B 2904 G A U G C C C U G G C A G
SEQRES 4 B 2904 U C A G A G G C G A U G A
SEQRES 5 B 2904 A G G A C G U G C U A A U
SEQRES 6 B 2904 C U G C G A U A A G C G U
SEQRES 7 B 2904 C G G U A A G G U G A U A
SEQRES 8 B 2904 U G A A C C G U U A U A A
SEQRES 9 B 2904 C C G G C G A U U U C C G
SEQRES 10 B 2904 A A U G G G G A A A C C C
SEQRES 11 B 2904 A G U G U G U U U C G A C
SEQRES 12 B 2904 A C A C U A U C A U U A A
SEQRES 13 B 2904 C U G A A U C C A U A G G
SEQRES 14 B 2904 U U A A U G A G G C G A A
SEQRES 15 B 2904 C C G G G G G A A C U G A
SEQRES 16 B 2904 A A C A U C U A A G U A C
SEQRES 17 B 2904 C C C G A G G A A A A G A
SEQRES 18 B 2904 A A U C A A C C G A G A U
SEQRES 19 B 2904 U C C C C C A G U A G C G
SEQRES 20 B 2904 G C G A G C G A A C G G G
SEQRES 21 B 2904 G A G C A G C C C A G A G
SEQRES 22 B 2904 C C U G A A U C A G U G U
SEQRES 23 B 2904 G U G U G U U A G U G G A
SEQRES 24 B 2904 A G C G U C U G G A A A G
SEQRES 25 B 2904 G C G C G C G A U A C A G
SEQRES 26 B 2904 G G U G A C A G C C C C G
SEQRES 27 B 2904 U A C A C A A A A A U G C
SEQRES 28 B 2904 A C A U G C U G U G A G C
SEQRES 29 B 2904 U C G A U G A G U A G G G
SEQRES 30 B 2904 C G G G A C A C G U G G U
SEQRES 31 B 2904 A U C C U G U C U G A A U
SEQRES 32 B 2904 A U G G G G G G A C C A U
SEQRES 33 B 2904 C C U C C A A G G C U A A
SEQRES 34 B 2904 A U A C U C C U G A C U G
SEQRES 35 B 2904 A C C G A U A G U G A A C
SEQRES 36 B 2904 C A G U A C C G U G A G G
SEQRES 37 B 2904 G A A A G G C G A A A A G
SEQRES 38 B 2904 A A C C C C G G C G A G G
SEQRES 39 B 2904 G G A G U G A A A A A G A
SEQRES 40 B 2904 A C C U G A A A C C G U G
SEQRES 41 B 2904 U A C G U A C A A G C A G
SEQRES 42 B 2904 U G G G A G C A C G C U U
SEQRES 43 B 2904 A G G C G U G U G A C U G
SEQRES 44 B 2904 C G U A C C U U U U G U A
SEQRES 45 B 2904 U A A U G G G U C A G C G
SEQRES 46 B 2904 A C U U A U A U U C U G U
SEQRES 47 B 2904 A G C A A G G U U A A C C
SEQRES 48 B 2904 G A A U A G G G G A G C C
SEQRES 49 B 2904 G A A G G G A A A C C G A
SEQRES 50 B 2904 G U C U U A A C U G G G C
SEQRES 51 B 2904 G U U A A G U U G C A G G
SEQRES 52 B 2904 G U A U A G A C C C G A A
SEQRES 53 B 2904 A C C C G G U G A U C U A
SEQRES 54 B 2904 G C C A U G G G C A G G U
SEQRES 55 B 2904 U G A A G G U U G G G U A
SEQRES 56 B 2904 A C A C U A A C U G G A G
SEQRES 57 B 2904 G A C C G A A C C G A C U
SEQRES 58 B 2904 A A U 1MG PSU 5MU G A A A A A U
SEQRES 59 B 2904 U A G C G G A U G A C U U
SEQRES 60 B 2904 G U G G C U G G G G G U G
SEQRES 61 B 2904 A A A G G C C A A U C A A
SEQRES 62 B 2904 A C C G G G A G A U A G C
SEQRES 63 B 2904 U G G U U C U C C C C G A
SEQRES 64 B 2904 A A G C U A U U U A G G U
SEQRES 65 B 2904 A G C G C C U C G U G A A
SEQRES 66 B 2904 U U C A U C U C C G G G G
SEQRES 67 B 2904 G U A G A G C A C U G U U
SEQRES 68 B 2904 U C G G C A A G G G G G U
SEQRES 69 B 2904 C A U C C C G A C U U A C
SEQRES 70 B 2904 C A A C C C G A U G C A A
SEQRES 71 B 2904 A C U G C G A A U A C C G
SEQRES 72 B 2904 G A G A A U G U U A U C A
SEQRES 73 B 2904 C G G G A G A C A C A C G
SEQRES 74 B 2904 G C G G G PSU G C U A A C G
SEQRES 75 B 2904 U C C G U C G U G A A G A
SEQRES 76 B 2904 G G G A A A C A A C C C A
SEQRES 77 B 2904 G A C C G C C A G C U A A
SEQRES 78 B 2904 G G U C C C A A A G U C A
SEQRES 79 B 2904 U G G U U A A G U G G G A
SEQRES 80 B 2904 A A C G A U G U G G G A A
SEQRES 81 B 2904 G G C C C A G A C A G C C
SEQRES 82 B 2904 A G G A U G U U G G C U U
SEQRES 83 B 2904 A G A A G C A G C C A U C
SEQRES 84 B 2904 A U U U A A A G A A A G C
SEQRES 85 B 2904 G U A A U A G C U C A C U
SEQRES 86 B 2904 G G U C G A G U C G G C C
SEQRES 87 B 2904 U G C G C G G A A G A U G
SEQRES 88 B 2904 U A A C G G G G C U A A A
SEQRES 89 B 2904 C C A U G C A C C G A A G
SEQRES 90 B 2904 C U G C G G C A G C G A C
SEQRES 91 B 2904 G C U U A U G C G U U G U
SEQRES 92 B 2904 U G G G U A G G G G A G C
SEQRES 93 B 2904 G U U C U G U A A G C C U
SEQRES 94 B 2904 G C G A A G G U G U G C U
SEQRES 95 B 2904 G U G A G G C A U G C U G
SEQRES 96 B 2904 G A G G U A U C A G A A G
SEQRES 97 B 2904 U G C G A A U G C U G A C
SEQRES 98 B 2904 A U A A G U A A C G A U A
SEQRES 99 B 2904 A A G C G G G U G A A A A
SEQRES 100 B 2904 G C C C G C U C G C C G G
SEQRES 101 B 2904 A A G A C C A A G G G U U
SEQRES 102 B 2904 C C U G U C C A A C G U U
SEQRES 103 B 2904 A A U C G G G G C A G G G
SEQRES 104 B 2904 U G A G U C G A C C C C U
SEQRES 105 B 2904 A A G G C G A G G C C G A
SEQRES 106 B 2904 A A G G C G U A G U C G A
SEQRES 107 B 2904 U G G G A A A C A G G U U
SEQRES 108 B 2904 A A U A U U C C U G U A C
SEQRES 109 B 2904 U U G G U G U U A C U G C
SEQRES 110 B 2904 G A A G G G G G G A C G G
SEQRES 111 B 2904 A G A A G G C U A U G U U
SEQRES 112 B 2904 G G C C G G G C G A C G G
SEQRES 113 B 2904 U U G U C C C G G U U U A
SEQRES 114 B 2904 A G C G U G U A G G C U G
SEQRES 115 B 2904 G U U U U C C A G G C A A
SEQRES 116 B 2904 A U C C G G A A A A U C A
SEQRES 117 B 2904 A G G C U G A G G C G U G
SEQRES 118 B 2904 A U G A C G A G G C A C U
SEQRES 119 B 2904 A C G G U G C U G A A G C
SEQRES 120 B 2904 A A C A A A U G C C C U G
SEQRES 121 B 2904 C U U C C A G G A A A A G
SEQRES 122 B 2904 C C U C U A A G C A U C A
SEQRES 123 B 2904 G G U A A C A U C A A A U
SEQRES 124 B 2904 C G U A C C C C A A A C C
SEQRES 125 B 2904 G A C A C 6MZ G G U G G U C
SEQRES 126 B 2904 A G G U A G A G A A U A C
SEQRES 127 B 2904 C A A G G C G C U U G A G
SEQRES 128 B 2904 A G A A C U C G G G U G A
SEQRES 129 B 2904 A G G A A C U A G G C A A
SEQRES 130 B 2904 A A U G G U G C C G U A A
SEQRES 131 B 2904 C U U C G G G A G A A G G
SEQRES 132 B 2904 C A C G C U G A U A U G U
SEQRES 133 B 2904 A G G U G A G G U C C C U
SEQRES 134 B 2904 C G C G G A U G G A G C U
SEQRES 135 B 2904 G A A A U C A G U C G A A
SEQRES 136 B 2904 G A U A C C A G C U G G C
SEQRES 137 B 2904 U G C A A C U G U U U A U
SEQRES 138 B 2904 U A A A A A C A C A G C A
SEQRES 139 B 2904 C U G U G C A A A C A C G
SEQRES 140 B 2904 A A A G U G G A C G U A U
SEQRES 141 B 2904 A C G G U G U G A C G C C
SEQRES 142 B 2904 U 2MG C C C G G U G C C G G
SEQRES 143 B 2904 A A G G U U A A U U G A U
SEQRES 144 B 2904 G G G G U U A G C G C A A
SEQRES 145 B 2904 G C G A A G C U C U U G A
SEQRES 146 B 2904 U C G A A G C C C C G G U
SEQRES 147 B 2904 A A A C G G C G G C C G PSU
SEQRES 148 B 2904 A A C 3TD A PSU A A C G G U C
SEQRES 149 B 2904 C U A A G G U A G C G A A
SEQRES 150 B 2904 A 5MU U C C U U G U C G G G
SEQRES 151 B 2904 U A A G U U C C G A C 5MC U
SEQRES 152 B 2904 G C A C G A A U G G C G U
SEQRES 153 B 2904 A A U G A U G G C C A G G
SEQRES 154 B 2904 C U G U C U C C A C C C G
SEQRES 155 B 2904 A G A C U C A G U G A A A
SEQRES 156 B 2904 U U G A A C U C G C U G U
SEQRES 157 B 2904 G 6MZ A G A U G C A G U G U
SEQRES 158 B 2904 A C C C G C G G C A A G A
SEQRES 159 B 2904 C G G A A A G A C C C C G
SEQRES 160 B 2904 U 7MG A A C C U U U A C U A
SEQRES 161 B 2904 U A G C U U G A C A C U G
SEQRES 162 B 2904 A A C A U U G A G C C U U
SEQRES 163 B 2904 G A U G U G U A G G A U A
SEQRES 164 B 2904 G G U G G G A G G C U U U
SEQRES 165 B 2904 G A A G U G U G G A C G C
SEQRES 166 B 2904 C A G U C U G C A U G G A
SEQRES 167 B 2904 G C C G A C C U U G A A A
SEQRES 168 B 2904 U A C C A C C C U U U A A
SEQRES 169 B 2904 U G U U U G A U G U U C U
SEQRES 170 B 2904 A A C G U U G A C C C G U
SEQRES 171 B 2904 A A U C C G G G U U G C G
SEQRES 172 B 2904 G A C A G U G U C U G G U
SEQRES 173 B 2904 G G G U A G U U U G A C U
SEQRES 174 B 2904 G OMG G G C G G U C U C C U
SEQRES 175 B 2904 C C U A A A G A G U A A C
SEQRES 176 B 2904 G G A G G A G C A C G A A
SEQRES 177 B 2904 G G U U G G C U A A U C C
SEQRES 178 B 2904 U G G U C G G A C A U C A
SEQRES 179 B 2904 G G A G G U U A G U G C A
SEQRES 180 B 2904 A U G G C A U A A G C C A
SEQRES 181 B 2904 G C U U G A C U G C G A G
SEQRES 182 B 2904 C G U G A C G G C G C G A
SEQRES 183 B 2904 G C A G G U G C G A A A G
SEQRES 184 B 2904 C A G G U C A U A G U G A
SEQRES 185 B 2904 U C C G G U G G U U C U G
SEQRES 186 B 2904 A A U G G A A G G G C C A
SEQRES 187 B 2904 U C G C U C A A C G G A U
SEQRES 188 B 2904 A A A A G G U A C U C C G
SEQRES 189 B 2904 2MG G G A H2U A A C A G G C PSU
SEQRES 190 B 2904 G A U A C C G C C C A A G
SEQRES 191 B 2904 A G U U C A U A U C G A C
SEQRES 192 B 2904 G G C G G U G U U U G G C
SEQRES 193 B 2904 A OMC C U C G 2MA PSU G U C G G
SEQRES 194 B 2904 C U C A U C A C A U C C U
SEQRES 195 B 2904 G G G G C U G A A G U A G
SEQRES 196 B 2904 G U C C C A A G G G U A U
SEQRES 197 B 2904 G G C OMU G U U C G C C A U
SEQRES 198 B 2904 U U A A A G U G G U A C G
SEQRES 199 B 2904 CH G A G C PSU G G G U U U A
SEQRES 200 B 2904 G A A C G U C G U G A G A
SEQRES 201 B 2904 C A G U PSU C G G U C C C U
SEQRES 202 B 2904 A U C U G C C G U G G G C
SEQRES 203 B 2904 G C U G G A G A A C U G A
SEQRES 204 B 2904 G G G G G G C U G C U C C
SEQRES 205 B 2904 U A G U A C G A G A G G A
SEQRES 206 B 2904 C C G G A G U G G A C G C
SEQRES 207 B 2904 A U C A C U G G U G U U C
SEQRES 208 B 2904 G G G U U G U C A U G C C
SEQRES 209 B 2904 A A U G G C A C U G C C C
SEQRES 210 B 2904 G G U A G C U A A A U G C
SEQRES 211 B 2904 G G A A G A G A U A A G U
SEQRES 212 B 2904 G C U G A A A G C A U C U
SEQRES 213 B 2904 A A G C A C G A A A C U U
SEQRES 214 B 2904 G C C C C G A G A U G A G
SEQRES 215 B 2904 U U C U C C C U G A C C C
SEQRES 216 B 2904 U U U A A G G G U C C U G
SEQRES 217 B 2904 A A G G A A C G U U G A A
SEQRES 218 B 2904 G A C G A C G A C G U U G
SEQRES 219 B 2904 A U A G G C C G G G U G U
SEQRES 220 B 2904 G U A A G C G C A G C G A
SEQRES 221 B 2904 U G C G U U G A G C U A A
SEQRES 222 B 2904 C C G G U A C U A A U G A
SEQRES 223 B 2904 A C C G U G A G G C U U A
SEQRES 224 B 2904 A C C U U
SEQRES 1 C 234 MET ALA LYS LEU THR LYS ARG MET ARG VAL ILE ARG GLU
SEQRES 2 C 234 LYS VAL ASP ALA THR LYS GLN TYR ASP ILE ASN GLU ALA
SEQRES 3 C 234 ILE ALA LEU LEU LYS GLU LEU ALA THR ALA LYS PHE VAL
SEQRES 4 C 234 GLU SER VAL ASP VAL ALA VAL ASN LEU GLY ILE ASP ALA
SEQRES 5 C 234 ARG LYS SER ASP GLN ASN VAL ARG GLY ALA THR VAL LEU
SEQRES 6 C 234 PRO HIS GLY THR GLY ARG SER VAL ARG VAL ALA VAL PHE
SEQRES 7 C 234 THR GLN GLY ALA ASN ALA GLU ALA ALA LYS ALA ALA GLY
SEQRES 8 C 234 ALA GLU LEU VAL GLY MET GLU ASP LEU ALA ASP GLN ILE
SEQRES 9 C 234 LYS LYS GLY GLU MET ASN PHE ASP VAL VAL ILE ALA SER
SEQRES 10 C 234 PRO ASP ALA MET ARG VAL VAL GLY GLN LEU GLY GLN VAL
SEQRES 11 C 234 LEU GLY PRO ARG GLY LEU MET PRO ASN PRO LYS VAL GLY
SEQRES 12 C 234 THR VAL THR PRO ASN VAL ALA GLU ALA VAL LYS ASN ALA
SEQRES 13 C 234 LYS ALA GLY GLN VAL ARG TYR ARG ASN ASP LYS ASN GLY
SEQRES 14 C 234 ILE ILE HIS THR THR ILE GLY LYS VAL ASP PHE ASP ALA
SEQRES 15 C 234 ASP LYS LEU LYS GLU ASN LEU GLU ALA LEU LEU VAL ALA
SEQRES 16 C 234 LEU LYS LYS ALA LYS PRO THR GLN ALA LYS GLY VAL TYR
SEQRES 17 C 234 ILE LYS LYS VAL SER ILE SER THR THR MET GLY ALA GLY
SEQRES 18 C 234 VAL ALA VAL ASP GLN ALA GLY LEU SER ALA SER VAL ASN
SEQRES 1 D 273 MET ALA VAL VAL LYS CYS LYS PRO THR SER PRO GLY ARG
SEQRES 2 D 273 ARG HIS VAL VAL LYS VAL VAL ASN PRO GLU LEU HIS LYS
SEQRES 3 D 273 GLY LYS PRO PHE ALA PRO LEU LEU GLU LYS ASN SER LYS
SEQRES 4 D 273 SER GLY GLY ARG ASN ASN ASN GLY ARG ILE THR THR ARG
SEQRES 5 D 273 HIS ILE GLY GLY GLY HIS LYS GLN ALA TYR ARG ILE VAL
SEQRES 6 D 273 ASP PHE LYS ARG ASN LYS ASP GLY ILE PRO ALA VAL VAL
SEQRES 7 D 273 GLU ARG LEU GLU TYR ASP PRO ASN ARG SER ALA ASN ILE
SEQRES 8 D 273 ALA LEU VAL LEU TYR LYS ASP GLY GLU ARG ARG TYR ILE
SEQRES 9 D 273 LEU ALA PRO LYS GLY LEU LYS ALA GLY ASP GLN ILE GLN
SEQRES 10 D 273 SER GLY VAL ASP ALA ALA ILE LYS PRO GLY ASN THR LEU
SEQRES 11 D 273 PRO MET ARG ASN ILE PRO VAL GLY SER THR VAL HIS ASN
SEQRES 12 D 273 VAL GLU MET LYS PRO GLY LYS GLY GLY GLN LEU ALA ARG
SEQRES 13 D 273 SER ALA GLY THR TYR VAL GLN ILE VAL ALA ARG ASP GLY
SEQRES 14 D 273 ALA TYR VAL THR LEU ARG LEU ARG SER GLY GLU MET ARG
SEQRES 15 D 273 LYS VAL GLU ALA ASP CYS ARG ALA THR LEU GLY GLU VAL
SEQRES 16 D 273 GLY ASN ALA GLU HIS MET LEU ARG VAL LEU GLY LYS ALA
SEQRES 17 D 273 GLY ALA ALA ARG TRP ARG GLY VAL ARG PRO THR VAL ARG
SEQRES 18 D 273 GLY THR ALA MET ASN PRO VAL ASP HIS PRO HIS GLY GLY
SEQRES 19 D 273 GLY GLU GLY ARG ASN PHE GLY LYS HIS PRO VAL THR PRO
SEQRES 20 D 273 TRP GLY VAL GLN THR LYS GLY LYS LYS THR ARG SER ASN
SEQRES 21 D 273 LYS ARG THR ASP LYS PHE ILE VAL ARG ARG ARG SER LYS
SEQRES 1 E 209 MET ILE GLY LEU VAL GLY LYS LYS VAL GLY MET THR ARG
SEQRES 2 E 209 ILE PHE THR GLU ASP GLY VAL SER ILE PRO VAL THR VAL
SEQRES 3 E 209 ILE GLU VAL GLU ALA ASN ARG VAL THR GLN VAL LYS ASP
SEQRES 4 E 209 LEU ALA ASN ASP GLY TYR ARG ALA ILE GLN VAL THR THR
SEQRES 5 E 209 GLY ALA LYS LYS ALA ASN ARG VAL THR LYS PRO GLU ALA
SEQRES 6 E 209 GLY HIS PHE ALA LYS ALA GLY VAL GLU ALA GLY ARG GLY
SEQRES 7 E 209 LEU TRP GLU PHE ARG LEU ALA GLU GLY GLU GLU PHE THR
SEQRES 8 E 209 VAL GLY GLN SER ILE SER VAL GLU LEU PHE ALA ASP VAL
SEQRES 9 E 209 LYS LYS VAL ASP VAL THR GLY THR SER LYS GLY LYS GLY
SEQRES 10 E 209 PHE ALA GLY THR VAL LYS ARG TRP ASN PHE ARG THR GLN
SEQRES 11 E 209 ASP ALA THR HIS GLY ASN SER LEU SER HIS ARG VAL PRO
SEQRES 12 E 209 GLY SER ILE GLY GLN ASN GLN THR PRO GLY LYS VAL PHE
SEQRES 13 E 209 LYS GLY LYS LYS MET ALA GLY GLN MET GLY ASN GLU ARG
SEQRES 14 E 209 VAL THR VAL GLN SER LEU ASP VAL VAL ARG VAL ASP ALA
SEQRES 15 E 209 GLU ARG ASN LEU LEU LEU VAL LYS GLY ALA VAL PRO GLY
SEQRES 16 E 209 ALA THR GLY SER ASP LEU ILE VAL LYS PRO ALA VAL LYS
SEQRES 17 E 209 ALA
SEQRES 1 F 201 MET GLU LEU VAL LEU LYS ASP ALA GLN SER ALA LEU THR
SEQRES 2 F 201 VAL SER GLU THR THR PHE GLY ARG ASP PHE ASN GLU ALA
SEQRES 3 F 201 LEU VAL HIS GLN VAL VAL VAL ALA TYR ALA ALA GLY ALA
SEQRES 4 F 201 ARG GLN GLY THR ARG ALA GLN LYS THR ARG ALA GLU VAL
SEQRES 5 F 201 THR GLY SER GLY LYS LYS PRO TRP ARG GLN LYS GLY THR
SEQRES 6 F 201 GLY ARG ALA ARG SER GLY SER ILE LYS SER PRO ILE TRP
SEQRES 7 F 201 ARG SER GLY GLY VAL THR PHE ALA ALA ARG PRO GLN ASP
SEQRES 8 F 201 HIS SER GLN LYS VAL ASN LYS LYS MET TYR ARG GLY ALA
SEQRES 9 F 201 LEU LYS SER ILE LEU SER GLU LEU VAL ARG GLN ASP ARG
SEQRES 10 F 201 LEU ILE VAL VAL GLU LYS PHE SER VAL GLU ALA PRO LYS
SEQRES 11 F 201 THR LYS LEU LEU ALA GLN LYS LEU LYS ASP MET ALA LEU
SEQRES 12 F 201 GLU ASP VAL LEU ILE ILE THR GLY GLU LEU ASP GLU ASN
SEQRES 13 F 201 LEU PHE LEU ALA ALA ARG ASN LEU HIS LYS VAL ASP VAL
SEQRES 14 F 201 ARG ASP ALA THR GLY ILE ASP PRO VAL SER LEU ILE ALA
SEQRES 15 F 201 PHE ASP LYS VAL VAL MET THR ALA ASP ALA VAL LYS GLN
SEQRES 16 F 201 VAL GLU GLU MET LEU ALA
SEQRES 1 G 179 MET ALA LYS LEU HIS ASP TYR TYR LYS ASP GLU VAL VAL
SEQRES 2 G 179 LYS LYS LEU MET THR GLU PHE ASN TYR ASN SER VAL MET
SEQRES 3 G 179 GLN VAL PRO ARG VAL GLU LYS ILE THR LEU ASN MET GLY
SEQRES 4 G 179 VAL GLY GLU ALA ILE ALA ASP LYS LYS LEU LEU ASP ASN
SEQRES 5 G 179 ALA ALA ALA ASP LEU ALA ALA ILE SER GLY GLN LYS PRO
SEQRES 6 G 179 LEU ILE THR LYS ALA ARG LYS SER VAL ALA GLY PHE LYS
SEQRES 7 G 179 ILE ARG GLN GLY TYR PRO ILE GLY CYS LYS VAL THR LEU
SEQRES 8 G 179 ARG GLY GLU ARG MET TRP GLU PHE PHE GLU ARG LEU ILE
SEQRES 9 G 179 THR ILE ALA VAL PRO ARG ILE ARG ASP PHE ARG GLY LEU
SEQRES 10 G 179 SER ALA LYS SER PHE ASP GLY ARG GLY ASN TYR SER MET
SEQRES 11 G 179 GLY VAL ARG GLU GLN ILE ILE PHE PRO GLU ILE ASP TYR
SEQRES 12 G 179 ASP LYS VAL ASP ARG VAL ARG GLY LEU ASP ILE THR ILE
SEQRES 13 G 179 THR THR THR ALA LYS SER ASP GLU GLU GLY ARG ALA LEU
SEQRES 14 G 179 LEU ALA ALA PHE ASP PHE PRO PHE ARG LYS
SEQRES 1 H 177 MET SER ARG VAL ALA LYS ALA PRO VAL VAL VAL PRO ALA
SEQRES 2 H 177 GLY VAL ASP VAL LYS ILE ASN GLY GLN VAL ILE THR ILE
SEQRES 3 H 177 LYS GLY LYS ASN GLY GLU LEU THR ARG THR LEU ASN ASP
SEQRES 4 H 177 ALA VAL GLU VAL LYS HIS ALA ASP ASN THR LEU THR PHE
SEQRES 5 H 177 GLY PRO ARG ASP GLY TYR ALA ASP GLY TRP ALA GLN ALA
SEQRES 6 H 177 GLY THR ALA ARG ALA LEU LEU ASN SER MET VAL ILE GLY
SEQRES 7 H 177 VAL THR GLU GLY PHE THR LYS LYS LEU GLN LEU VAL GLY
SEQRES 8 H 177 VAL GLY TYR ARG ALA ALA VAL LYS GLY ASN VAL ILE ASN
SEQRES 9 H 177 LEU SER LEU GLY PHE SER HIS PRO VAL ASP HIS GLN LEU
SEQRES 10 H 177 PRO ALA GLY ILE THR ALA GLU CYS PRO THR GLN THR GLU
SEQRES 11 H 177 ILE VAL LEU LYS GLY ALA ASP LYS GLN VAL ILE GLY GLN
SEQRES 12 H 177 VAL ALA ALA ASP LEU ARG ALA TYR ARG ARG PRO GLU PRO
SEQRES 13 H 177 TYR LYS GLY LYS GLY VAL ARG TYR ALA ASP GLU VAL VAL
SEQRES 14 H 177 ARG THR LYS GLU ALA LYS LYS LYS
SEQRES 1 I 149 MET GLN VAL ILE LEU LEU ASP LYS VAL ALA ASN LEU GLY
SEQRES 2 I 149 SER LEU GLY ASP GLN VAL ASN VAL LYS ALA GLY TYR ALA
SEQRES 3 I 149 ARG ASN PHE LEU VAL PRO GLN GLY LYS ALA VAL PRO ALA
SEQRES 4 I 149 THR LYS LYS ASN ILE GLU PHE PHE GLU ALA ARG ARG ALA
SEQRES 5 I 149 GLU LEU GLU ALA LYS LEU ALA GLU VAL LEU ALA ALA ALA
SEQRES 6 I 149 ASN ALA ARG ALA GLU LYS ILE ASN ALA LEU GLU THR VAL
SEQRES 7 I 149 THR ILE ALA SER LYS ALA GLY ASP GLU GLY LYS LEU PHE
SEQRES 8 I 149 GLY SER ILE GLY THR ARG ASP ILE ALA ASP ALA VAL THR
SEQRES 9 I 149 ALA ALA GLY VAL GLU VAL ALA LYS SER GLU VAL ARG LEU
SEQRES 10 I 149 PRO ASN GLY VAL LEU ARG THR THR GLY GLU HIS GLU VAL
SEQRES 11 I 149 SER PHE GLN VAL HIS SER GLU VAL PHE ALA LYS VAL ILE
SEQRES 12 I 149 VAL ASN VAL VAL ALA GLU
SEQRES 1 J 142 MET ALA LYS LYS VAL GLN ALA TYR VAL LYS LEU GLN VAL
SEQRES 2 J 142 ALA ALA GLY MET ALA ASN PRO SER PRO PRO VAL GLY PRO
SEQRES 3 J 142 ALA LEU GLY GLN GLN GLY VAL ASN ILE MET GLU PHE CYS
SEQRES 4 J 142 LYS ALA PHE ASN ALA LYS THR ASP SER ILE GLU LYS GLY
SEQRES 5 J 142 LEU PRO ILE PRO VAL VAL ILE THR VAL TYR ALA ASP ARG
SEQRES 6 J 142 SER PHE THR PHE VAL THR LYS THR PRO PRO ALA ALA VAL
SEQRES 7 J 142 LEU LEU LYS LYS ALA ALA GLY ILE LYS SER GLY SER GLY
SEQRES 8 J 142 LYS PRO ASN LYS ASP LYS VAL GLY LYS ILE SER ARG ALA
SEQRES 9 J 142 GLN LEU GLN GLU ILE ALA GLN THR LYS ALA ALA ASP MET
SEQRES 10 J 142 THR GLY ALA ASP ILE GLU ALA MET THR ARG SER ILE GLU
SEQRES 11 J 142 GLY THR ALA ARG SER MET GLY LEU VAL VAL GLU ASP
SEQRES 1 K 142 MET LYS THR PHE THR ALA LYS PRO GLU THR VAL LYS ARG
SEQRES 2 K 142 ASP TRP TYR VAL VAL ASP ALA THR GLY LYS THR LEU GLY
SEQRES 3 K 142 ARG LEU ALA THR GLU LEU ALA ARG ARG LEU ARG GLY LYS
SEQRES 4 K 142 HIS LYS ALA GLU TYR THR PRO HIS VAL ASP THR GLY ASP
SEQRES 5 K 142 TYR ILE ILE VAL LEU ASN ALA ASP LYS VAL ALA VAL THR
SEQRES 6 K 142 GLY ASN LYS ARG THR ASP LYS VAL TYR TYR HIS HIS THR
SEQRES 7 K 142 GLY HIS ILE GLY GLY ILE LYS GLN ALA THR PHE GLU GLU
SEQRES 8 K 142 MET ILE ALA ARG ARG PRO GLU ARG VAL ILE GLU ILE ALA
SEQRES 9 K 142 VAL LYS GLY MET LEU PRO LYS GLY PRO LEU GLY ARG ALA
SEQRES 10 K 142 MET PHE ARG LYS LEU LYS VAL TYR ALA GLY ASN GLU HIS
SEQRES 11 K 142 ASN HIS ALA ALA GLN GLN PRO GLN VAL LEU ASP ILE
SEQRES 1 L 123 MET ILE GLN GLU GLN THR MET LEU ASN VAL ALA ASP ASN
SEQRES 2 L 123 SER GLY ALA ARG ARG VAL MET CYS ILE LYS VAL LEU GLY
SEQRES 3 L 123 GLY SER HIS ARG ARG TYR ALA GLY VAL GLY ASP ILE ILE
SEQRES 4 L 123 LYS ILE THR ILE LYS GLU ALA ILE PRO ARG GLY LYS VAL
SEQRES 5 L 123 LYS LYS GLY ASP VAL LEU LYS ALA VAL VAL VAL ARG THR
SEQRES 6 L 123 LYS LYS GLY VAL ARG ARG PRO ASP GLY SER VAL ILE ARG
SEQRES 7 L 123 PHE ASP GLY ASN ALA CYS VAL LEU LEU ASN ASN ASN SER
SEQRES 8 L 123 GLU GLN PRO ILE GLY THR ARG ILE PHE GLY PRO VAL THR
SEQRES 9 L 123 ARG GLU LEU ARG SER GLU LYS PHE MET LYS ILE ILE SER
SEQRES 10 L 123 LEU ALA PRO GLU VAL LEU
SEQRES 1 M 144 MET ARG LEU ASN THR LEU SER PRO ALA GLU GLY SER LYS
SEQRES 2 M 144 LYS ALA GLY LYS ARG LEU GLY ARG GLY ILE GLY SER GLY
SEQRES 3 M 144 LEU GLY LYS THR GLY GLY ARG GLY HIS LYS GLY GLN LYS
SEQRES 4 M 144 SER ARG SER GLY GLY GLY VAL ARG ARG GLY PHE GLU GLY
SEQRES 5 M 144 GLY GLN MET PRO LEU TYR ARG ARG LEU PRO LYS PHE GLY
SEQRES 6 M 144 PHE THR SER ARG LYS ALA ALA ILE THR ALA GLU ILE ARG
SEQRES 7 M 144 LEU SER ASP LEU ALA LYS VAL GLU GLY GLY VAL VAL ASP
SEQRES 8 M 144 LEU ASN THR LEU LYS ALA ALA ASN ILE ILE GLY ILE GLN
SEQRES 9 M 144 ILE GLU PHE ALA LYS VAL ILE LEU ALA GLY GLU VAL THR
SEQRES 10 M 144 THR PRO VAL THR VAL ARG GLY LEU ARG VAL THR LYS GLY
SEQRES 11 M 144 ALA ARG ALA ALA ILE GLU ALA ALA GLY GLY LYS ILE GLU
SEQRES 12 M 144 GLU
SEQRES 1 N 136 MET LEU GLN PRO LYS ARG THR LYS PHE ARG LYS MET HIS
SEQRES 2 N 136 LYS GLY ARG ASN ARG GLY LEU ALA GLN GLY THR ASP VAL
SEQRES 3 N 136 SER PHE GLY SER PHE GLY LEU LYS ALA VAL GLY ARG GLY
SEQRES 4 N 136 ARG LEU THR ALA ARG GLN ILE GLU ALA ALA ARG ARG ALA
SEQRES 5 N 136 MET THR ARG ALA VAL LYS ARG GLN GLY LYS ILE TRP ILE
SEQRES 6 N 136 ARG VAL PHE PRO ASP LYS PRO ILE THR GLU LYS PRO LEU
SEQRES 7 N 136 ALA VAL ARG MET GLY LYS GLY LYS GLY ASN VAL GLU TYR
SEQRES 8 N 136 TRP VAL ALA LEU ILE GLN PRO GLY LYS VAL LEU TYR GLU
SEQRES 9 N 136 MET ASP GLY VAL PRO GLU GLU LEU ALA ARG GLU ALA PHE
SEQRES 10 N 136 LYS LEU ALA ALA ALA LYS LEU PRO ILE LYS THR THR PHE
SEQRES 11 N 136 VAL THR LYS THR VAL MET
SEQRES 1 O 127 MET ARG HIS ARG LYS SER GLY ARG GLN LEU ASN ARG ASN
SEQRES 2 O 127 SER SER HIS ARG GLN ALA MET PHE ARG ASN MET ALA GLY
SEQRES 3 O 127 SER LEU VAL ARG HIS GLU ILE ILE LYS THR THR LEU PRO
SEQRES 4 O 127 LYS ALA LYS GLU LEU ARG ARG VAL VAL GLU PRO LEU ILE
SEQRES 5 O 127 THR LEU ALA LYS THR ASP SER VAL ALA ASN ARG ARG LEU
SEQRES 6 O 127 ALA PHE ALA ARG THR ARG ASP ASN GLU ILE VAL ALA LYS
SEQRES 7 O 127 LEU PHE ASN GLU LEU GLY PRO ARG PHE ALA SER ARG ALA
SEQRES 8 O 127 GLY GLY TYR THR ARG ILE LEU LYS CYS GLY PHE ARG ALA
SEQRES 9 O 127 GLY ASP ASN ALA PRO MET ALA TYR ILE GLU LEU VAL ASP
SEQRES 10 O 127 ARG SER GLU LYS ALA GLU ALA ALA ALA GLU
SEQRES 1 P 117 MET ASP LYS LYS SER ALA ARG ILE ARG ARG ALA THR ARG
SEQRES 2 P 117 ALA ARG ARG LYS LEU GLN GLU LEU GLY ALA THR ARG LEU
SEQRES 3 P 117 VAL VAL HIS ARG THR PRO ARG HIS ILE TYR ALA GLN VAL
SEQRES 4 P 117 ILE ALA PRO ASN GLY SER GLU VAL LEU VAL ALA ALA SER
SEQRES 5 P 117 THR VAL GLU LYS ALA ILE ALA GLU GLN LEU LYS TYR THR
SEQRES 6 P 117 GLY ASN LYS ASP ALA ALA ALA ALA VAL GLY LYS ALA VAL
SEQRES 7 P 117 ALA GLU ARG ALA LEU GLU LYS GLY ILE LYS ASP VAL SER
SEQRES 8 P 117 PHE ASP ARG SER GLY PHE GLN TYR HIS GLY ARG VAL GLN
SEQRES 9 P 117 ALA LEU ALA ASP ALA ALA ARG GLU ALA GLY LEU GLN PHE
SEQRES 1 Q 115 MET SER ASN ILE ILE LYS GLN LEU GLU GLN GLU GLN MET
SEQRES 2 Q 115 LYS GLN ASP VAL PRO SER PHE ARG PRO GLY ASP THR VAL
SEQRES 3 Q 115 GLU VAL LYS VAL TRP VAL VAL GLU GLY SER LYS LYS ARG
SEQRES 4 Q 115 LEU GLN ALA PHE GLU GLY VAL VAL ILE ALA ILE ARG ASN
SEQRES 5 Q 115 ARG GLY LEU HIS SER ALA PHE THR VAL ARG LYS ILE SER
SEQRES 6 Q 115 ASN GLY GLU GLY VAL GLU ARG VAL PHE GLN THR HIS SER
SEQRES 7 Q 115 PRO VAL VAL ASP SER ILE SER VAL LYS ARG ARG GLY ALA
SEQRES 8 Q 115 VAL ARG LYS ALA LYS LEU TYR TYR LEU ARG GLU ARG THR
SEQRES 9 Q 115 GLY LYS ALA ALA ARG ILE LYS GLU ARG LEU ASN
SEQRES 1 R 118 MET ALA ARG VAL LYS ARG GLY VAL ILE ALA ARG ALA ARG
SEQRES 2 R 118 HIS LYS LYS ILE LEU LYS GLN ALA LYS GLY TYR TYR GLY
SEQRES 3 R 118 ALA ARG SER ARG VAL TYR ARG VAL ALA PHE GLN ALA VAL
SEQRES 4 R 118 ILE LYS ALA GLY GLN TYR ALA TYR ARG ASP ARG ARG GLN
SEQRES 5 R 118 ARG LYS ARG GLN PHE ARG GLN LEU TRP ILE ALA ARG ILE
SEQRES 6 R 118 ASN ALA ALA ALA ARG GLN ASN GLY ILE SER TYR SER LYS
SEQRES 7 R 118 PHE ILE ASN GLY LEU LYS LYS ALA SER VAL GLU ILE ASP
SEQRES 8 R 118 ARG LYS ILE LEU ALA ASP ILE ALA VAL PHE ASP LYS VAL
SEQRES 9 R 118 ALA PHE THR ALA LEU VAL GLU LYS ALA LYS ALA ALA LEU
SEQRES 10 R 118 ALA
SEQRES 1 S 103 MET TYR ALA VAL PHE GLN SER GLY GLY LYS GLN HIS ARG
SEQRES 2 S 103 VAL SER GLU GLY GLN THR VAL ARG LEU GLU LYS LEU ASP
SEQRES 3 S 103 ILE ALA THR GLY GLU THR VAL GLU PHE ALA GLU VAL LEU
SEQRES 4 S 103 MET ILE ALA ASN GLY GLU GLU VAL LYS ILE GLY VAL PRO
SEQRES 5 S 103 PHE VAL ASP GLY GLY VAL ILE LYS ALA GLU VAL VAL ALA
SEQRES 6 S 103 HIS GLY ARG GLY GLU LYS VAL LYS ILE VAL LYS PHE ARG
SEQRES 7 S 103 ARG ARG LYS HIS TYR ARG LYS GLN GLN GLY HIS ARG GLN
SEQRES 8 S 103 TRP PHE THR ASP VAL LYS ILE THR GLY ILE SER ALA
SEQRES 1 T 110 MET GLU THR ILE ALA LYS HIS ARG HIS ALA ARG SER SER
SEQRES 2 T 110 ALA GLN LYS VAL ARG LEU VAL ALA ASP LEU ILE ARG GLY
SEQRES 3 T 110 LYS LYS VAL SER GLN ALA LEU ASP ILE LEU THR TYR THR
SEQRES 4 T 110 ASN LYS LYS ALA ALA VAL LEU VAL LYS LYS VAL LEU GLU
SEQRES 5 T 110 SER ALA ILE ALA ASN ALA GLU HIS ASN ASP GLY ALA ASP
SEQRES 6 T 110 ILE ASP ASP LEU LYS VAL THR LYS ILE PHE VAL ASP GLU
SEQRES 7 T 110 GLY PRO SER MET LYS ARG ILE MET PRO ARG ALA LYS GLY
SEQRES 8 T 110 ARG ALA ASP ARG ILE LEU LYS ARG THR SER HIS ILE THR
SEQRES 9 T 110 VAL VAL VAL SER ASP ARG
SEQRES 1 U 100 MET ILE ARG GLU GLU ARG LEU LEU LYS VAL LEU ARG ALA
SEQRES 2 U 100 PRO HIS VAL SER GLU LYS ALA SER THR ALA MET GLU LYS
SEQRES 3 U 100 SER ASN THR ILE VAL LEU LYS VAL ALA LYS ASP ALA THR
SEQRES 4 U 100 LYS ALA GLU ILE LYS ALA ALA VAL GLN LYS LEU PHE GLU
SEQRES 5 U 100 VAL GLU VAL GLU VAL VAL ASN THR LEU VAL VAL LYS GLY
SEQRES 6 U 100 LYS VAL LYS ARG HIS GLY GLN ARG ILE GLY ARG ARG SER
SEQRES 7 U 100 ASP TRP LYS LYS ALA TYR VAL THR LEU LYS GLU GLY GLN
SEQRES 8 U 100 ASN LEU ASP PHE VAL GLY GLY ALA GLU
SEQRES 1 V 104 MET ALA ALA LYS ILE ARG ARG ASP ASP GLU VAL ILE VAL
SEQRES 2 V 104 LEU THR GLY LYS ASP LYS GLY LYS ARG GLY LYS VAL LYS
SEQRES 3 V 104 ASN VAL LEU SER SER GLY LYS VAL ILE VAL GLU GLY ILE
SEQRES 4 V 104 ASN LEU VAL LYS LYS HIS GLN LYS PRO VAL PRO ALA LEU
SEQRES 5 V 104 ASN GLN PRO GLY GLY ILE VAL GLU LYS GLU ALA ALA ILE
SEQRES 6 V 104 GLN VAL SER ASN VAL ALA ILE PHE ASN ALA ALA THR GLY
SEQRES 7 V 104 LYS ALA ASP ARG VAL GLY PHE ARG PHE GLU ASP GLY LYS
SEQRES 8 V 104 LYS VAL ARG PHE PHE LYS SER ASN SER GLU THR ILE LYS
SEQRES 1 W 94 MET PHE THR ILE ASN ALA GLU VAL ARG LYS GLU GLN GLY
SEQRES 2 W 94 LYS GLY ALA SER ARG ARG LEU ARG ALA ALA ASN LYS PHE
SEQRES 3 W 94 PRO ALA ILE ILE TYR GLY GLY LYS GLU ALA PRO LEU ALA
SEQRES 4 W 94 ILE GLU LEU ASP HIS ASP LYS VAL MET ASN MET GLN ALA
SEQRES 5 W 94 LYS ALA GLU PHE TYR SER GLU VAL LEU THR ILE VAL VAL
SEQRES 6 W 94 ASP GLY LYS GLU ILE LYS VAL LYS ALA GLN ASP VAL GLN
SEQRES 7 W 94 ARG HIS PRO TYR LYS PRO LYS LEU GLN HIS ILE ASP PHE
SEQRES 8 W 94 VAL ARG ALA
SEQRES 1 X 85 MET ALA HIS LYS LYS ALA GLY GLY SER THR ARG ASN GLY
SEQRES 2 X 85 ARG ASP SER GLU ALA LYS ARG LEU GLY VAL LYS ARG PHE
SEQRES 3 X 85 GLY GLY GLU SER VAL LEU ALA GLY SER ILE ILE VAL ARG
SEQRES 4 X 85 GLN ARG GLY THR LYS PHE HIS ALA GLY ALA ASN VAL GLY
SEQRES 5 X 85 CYS GLY ARG ASP HIS THR LEU PHE ALA LYS ALA ASP GLY
SEQRES 6 X 85 LYS VAL LYS PHE GLU VAL LYS GLY PRO LYS ASN ARG LYS
SEQRES 7 X 85 PHE ILE SER ILE GLU ALA GLU
SEQRES 1 Y 78 MET SER ARG VAL CYS GLN VAL THR GLY LYS ARG PRO VAL
SEQRES 2 Y 78 THR GLY ASN ASN ARG SER HIS ALA LEU ASN ALA THR LYS
SEQRES 3 Y 78 ARG ARG PHE LEU PRO ASN LEU HIS SER HIS ARG PHE TRP
SEQRES 4 Y 78 VAL GLU SER GLU LYS ARG PHE VAL THR LEU ARG VAL SER
SEQRES 5 Y 78 ALA LYS GLY MET ARG VAL ILE ASP LYS LYS GLY ILE ASP
SEQRES 6 Y 78 THR VAL LEU ALA GLU LEU ARG ALA ARG GLY GLU LYS TYR
SEQRES 1 Z 63 MET LYS ALA LYS GLU LEU ARG GLU LYS SER VAL GLU GLU
SEQRES 2 Z 63 LEU ASN THR GLU LEU LEU ASN LEU LEU ARG GLU GLN PHE
SEQRES 3 Z 63 ASN LEU ARG MET GLN ALA ALA SER GLY GLN LEU GLN GLN
SEQRES 4 Z 63 SER HIS LEU LEU LYS GLN VAL ARG ARG ASP VAL ALA ARG
SEQRES 5 Z 63 VAL LYS THR LEU LEU ASN GLU LYS ALA GLY ALA
SEQRES 1 a 59 MET ALA LYS THR ILE LYS ILE THR GLN THR ARG SER ALA
SEQRES 2 a 59 ILE GLY ARG LEU PRO LYS HIS LYS ALA THR LEU LEU GLY
SEQRES 3 a 59 LEU GLY LEU ARG ARG ILE GLY HIS THR VAL GLU ARG GLU
SEQRES 4 a 59 ASP THR PRO ALA ILE ARG GLY MET ILE ASN ALA VAL SER
SEQRES 5 a 59 PHE MET VAL LYS VAL GLU GLU
SEQRES 1 b 70 MET LYS LYS ASP ILE HIS PRO LYS TYR GLU GLU ILE THR
SEQRES 2 b 70 ALA SER CYS SER CYS GLY ASN VAL MET LYS ILE ARG SER
SEQRES 3 b 70 THR VAL GLY HIS ASP LEU ASN LEU ASP VAL CYS SER LYS
SEQRES 4 b 70 CYS HIS PRO PHE PHE THR GLY LYS GLN ARG ASP VAL ALA
SEQRES 5 b 70 THR GLY GLY ARG VAL ASP ARG PHE ASN LYS ARG PHE ASN
SEQRES 6 b 70 ILE PRO GLY SER LYS
SEQRES 1 c 57 MET ALA VAL GLN GLN ASN LYS PRO THR ARG SER LYS ARG
SEQRES 2 c 57 GLY MET ARG ARG SER HIS ASP ALA LEU THR ALA VAL THR
SEQRES 3 c 57 SER LEU SER VAL ASP LYS THR SER GLY GLU LYS HIS LEU
SEQRES 4 c 57 ARG HIS HIS ILE THR ALA ASP GLY TYR TYR ARG GLY ARG
SEQRES 5 c 57 LYS VAL ILE ALA LYS
SEQRES 1 d 55 MET ALA LYS GLY ILE ARG GLU LYS ILE LYS LEU VAL SER
SEQRES 2 d 55 SER ALA GLY THR GLY HIS PHE TYR THR THR THR LYS ASN
SEQRES 3 d 55 LYS ARG THR LYS PRO GLU LYS LEU GLU LEU LYS LYS PHE
SEQRES 4 d 55 ASP PRO VAL VAL ARG GLN HIS VAL ILE TYR LYS GLU ALA
SEQRES 5 d 55 LYS ILE LYS
SEQRES 1 e 46 MET LYS ARG THR PHE GLN PRO SER VAL LEU LYS ARG ASN
SEQRES 2 e 46 ARG SER HIS GLY PHE ARG ALA ARG MET ALA THR LYS ASN
SEQRES 3 e 46 GLY ARG GLN VAL LEU ALA ARG ARG ARG ALA LYS GLY ARG
SEQRES 4 e 46 ALA ARG LEU THR VAL SER LYS
SEQRES 1 f 65 MET PRO LYS ILE LYS THR VAL ARG GLY ALA ALA LYS ARG
SEQRES 2 f 65 PHE LYS LYS THR GLY LYS GLY GLY PHE LYS HIS LYS HIS
SEQRES 3 f 65 ALA ASN LEU ARG HIS ILE LEU THR LYS LYS ALA THR LYS
SEQRES 4 f 65 ARG LYS ARG HIS LEU ARG PRO LYS ALA MET VAL SER LYS
SEQRES 5 f 65 GLY ASP LEU GLY LEU VAL ILE ALA CYS LEU PRO TYR ALA
SEQRES 1 g 38 MET LYS VAL ARG ALA SER VAL LYS LYS LEU CYS ARG ASN
SEQRES 2 g 38 CYS LYS ILE VAL LYS ARG ASP GLY VAL ILE ARG VAL ILE
SEQRES 3 g 38 CYS SER ALA GLU PRO LYS HIS LYS GLN ARG GLN GLY
MODRES 3IZU 1MG B 745 G 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
MODRES 3IZU PSU B 746 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU 5MU B 747 U 5-METHYLURIDINE 5'-MONOPHOSPHATE
MODRES 3IZU PSU B 955 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU 6MZ B 1618 A N6-METHYLADENOSINE-5'-MONOPHOSPHATE
MODRES 3IZU 2MG B 1835 G 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
MODRES 3IZU PSU B 1911 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU 3TD B 1915 U
MODRES 3IZU PSU B 1917 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU 5MU B 1939 U 5-METHYLURIDINE 5'-MONOPHOSPHATE
MODRES 3IZU 5MC B 1962 C 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
MODRES 3IZU 6MZ B 2030 A N6-METHYLADENOSINE-5'-MONOPHOSPHATE
MODRES 3IZU 7MG B 2069 G
MODRES 3IZU OMG B 2251 G O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
MODRES 3IZU 2MG B 2445 G 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
MODRES 3IZU H2U B 2449 U 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU PSU B 2457 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU OMC B 2498 C O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
MODRES 3IZU 2MA B 2503 A 2-METHYLADENOSINE-5'-MONOPHOSPHATE
MODRES 3IZU PSU B 2504 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU OMU B 2552 U O2'-METHYLURIDINE 5'-MONOPHOSPHATE
MODRES 3IZU CH B 2575 C N3-PROTONATED CYTIDINE-5'-MONOPHOSPHATE
MODRES 3IZU PSU B 2580 U PSEUDOURIDINE-5'-MONOPHOSPHATE
MODRES 3IZU PSU B 2605 U PSEUDOURIDINE-5'-MONOPHOSPHATE
HET 1MG B 745 24
HET PSU B 746 20
HET 5MU B 747 21
HET PSU B 955 20
HET 6MZ B1618 23
HET 2MG B1835 24
HET PSU B1911 20
HET 3TD B1915 21
HET PSU B1917 20
HET 5MU B1939 21
HET 5MC B1962 21
HET 6MZ B2030 23
HET 7MG B2069 24
HET OMG B2251 24
HET 2MG B2445 24
HET H2U B2449 20
HET PSU B2457 20
HET OMC B2498 21
HET 2MA B2503 23
HET PSU B2504 20
HET OMU B2552 21
HET CH B2575 20
HET PSU B2580 20
HET PSU B2605 20
HETNAM 1MG 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
HETNAM PSU PSEUDOURIDINE-5'-MONOPHOSPHATE
HETNAM 5MU 5-METHYLURIDINE 5'-MONOPHOSPHATE
HETNAM 6MZ N6-METHYLADENOSINE-5'-MONOPHOSPHATE
HETNAM 2MG 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
HETNAM 3TD (1S)-1,4-ANHYDRO-1-(3-METHYL-2,4-DIOXO-1,2,3,4-
HETNAM 2 3TD TETRAHYDROPYRIMIDIN-5-YL)-5-O-PHOSPHONO-D-RIBITOL
HETNAM 5MC 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
HETNAM 7MG 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE
HETNAM OMG O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
HETNAM H2U 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE
HETNAM OMC O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
HETNAM 2MA 2-METHYLADENOSINE-5'-MONOPHOSPHATE
HETNAM OMU O2'-METHYLURIDINE 5'-MONOPHOSPHATE
HETNAM CH N3-PROTONATED CYTIDINE-5'-MONOPHOSPHATE
FORMUL 2 1MG C11 H16 N5 O8 P
FORMUL 2 PSU 8(C9 H13 N2 O9 P)
FORMUL 2 5MU 2(C10 H15 N2 O9 P)
FORMUL 2 6MZ 2(C11 H16 N5 O7 P)
FORMUL 2 2MG 2(C11 H16 N5 O8 P)
FORMUL 2 3TD C10 H15 N2 O9 P
FORMUL 2 5MC C10 H16 N3 O8 P
FORMUL 2 7MG C11 H18 N5 O8 P
FORMUL 2 OMG C11 H16 N5 O8 P
FORMUL 2 H2U C9 H15 N2 O9 P
FORMUL 2 OMC C10 H16 N3 O8 P
FORMUL 2 2MA C11 H16 N5 O7 P
FORMUL 2 OMU C10 H15 N2 O9 P
FORMUL 2 CH C9 H15 N3 O8 P 1+
HELIX 1 1 ASP C 22 ALA C 34 1 13
HELIX 2 2 ASN C 83 ALA C 90 1 8
HELIX 3 3 ASP C 99 ILE C 104 1 6
HELIX 4 4 ALA C 120 GLY C 125 1 6
HELIX 5 5 ASN C 148 LYS C 157 1 10
HELIX 6 6 ASP C 181 LYS C 198 1 18
HELIX 7 7 PHE D 29 PRO D 31 5 3
HELIX 8 8 GLU D 198 ARG D 202 5 5
HELIX 9 9 ALA D 207 TRP D 212 1 6
HELIX 10 10 ARG D 220 MET D 224 5 5
HELIX 11 11 GLY D 234 PHE D 239 5 6
HELIX 12 12 THR D 262 LYS D 264 5 3
HELIX 13 13 THR E 61 GLY E 72 1 12
HELIX 14 14 SER E 97 PHE E 101 5 5
HELIX 15 15 ASN F 24 ALA F 39 1 16
HELIX 16 16 THR F 48 VAL F 52 5 5
HELIX 17 17 ASN F 97 GLN F 115 1 19
HELIX 18 18 LYS F 130 MET F 141 1 12
HELIX 19 19 ASP F 176 ILE F 181 1 6
HELIX 20 20 ASP F 191 VAL F 196 1 6
HELIX 21 21 VAL F 196 ALA F 201 1 6
HELIX 22 22 LYS G 2 GLU G 10 1 9
HELIX 23 23 GLU G 10 ASN G 20 1 11
HELIX 24 24 SER G 23 VAL G 27 5 5
HELIX 25 25 LYS G 47 ILE G 59 1 13
HELIX 26 26 GLY G 92 PHE G 98 1 7
HELIX 27 27 PHE G 99 LEU G 102 5 4
HELIX 28 28 ASP G 141 VAL G 145 5 5
HELIX 29 29 GLU G 164 LEU G 168 5 5
HELIX 30 30 GLN H 63 VAL H 78 1 16
HELIX 31 31 GLN H 138 TYR H 150 1 13
HELIX 32 32 GLU H 166 THR H 170 5 5
HELIX 33 33 VAL I 31 GLY I 34 5 4
HELIX 34 34 ILE I 44 GLU I 48 5 5
HELIX 35 35 ARG I 50 ALA I 59 1 10
HELIX 36 36 ILE I 99 THR I 104 1 6
HELIX 37 37 VAL J 23 GLY J 28 1 6
HELIX 38 38 GLN J 29 GLY J 31 5 3
HELIX 39 39 ASN J 33 ASP J 46 1 14
HELIX 40 40 PRO J 74 ALA J 83 1 10
HELIX 41 41 SER J 101 ALA J 113 1 13
HELIX 42 42 ALA J 114 MET J 116 5 3
HELIX 43 43 ASP J 120 GLY J 136 1 17
HELIX 44 44 LEU K 25 GLY K 38 1 14
HELIX 45 45 ASN K 67 LYS K 72 1 6
HELIX 46 46 PHE K 89 ILE K 93 1 5
HELIX 47 47 ARG K 96 GLU K 98 5 3
HELIX 48 48 ARG K 99 GLY K 107 1 9
HELIX 49 49 GLY K 112 ARG K 120 1 9
HELIX 50 50 SER L 109 LYS L 111 5 3
HELIX 51 51 PHE L 112 SER L 117 1 6
HELIX 52 52 PRO M 56 LEU M 61 1 6
HELIX 53 53 LYS M 70 ALA M 72 5 3
HELIX 54 54 LEU M 79 ALA M 83 1 5
HELIX 55 55 LYS M 84 GLU M 86 5 3
HELIX 56 56 THR M 128 ALA M 138 1 11
HELIX 57 57 ALA N 43 VAL N 57 1 15
HELIX 58 58 PRO N 109 LEU N 124 1 16
HELIX 59 59 ASN O 13 ARG O 30 1 18
HELIX 60 60 LEU O 38 LEU O 54 1 17
HELIX 61 61 ALA O 55 THR O 57 5 3
HELIX 62 62 SER O 59 ARG O 69 1 11
HELIX 63 63 ASN O 73 LEU O 79 1 7
HELIX 64 64 LEU O 83 ALA O 88 1 6
HELIX 65 65 ASP P 2 GLU P 20 1 19
HELIX 66 66 ALA P 57 GLN P 61 5 5
HELIX 67 67 LYS P 68 GLU P 84 1 17
HELIX 68 68 HIS P 100 ALA P 113 1 14
HELIX 69 69 LEU Q 7 GLN Q 11 5 5
HELIX 70 70 ARG Q 52 HIS Q 55 5 4
HELIX 71 71 LEU Q 96 GLU Q 101 5 6
HELIX 72 72 ILE R 8 LYS R 18 1 11
HELIX 73 73 GLY R 25 VAL R 30 1 6
HELIX 74 74 VAL R 30 PHE R 56 1 27
HELIX 75 75 PHE R 56 ARG R 69 1 14
HELIX 76 76 SER R 74 ALA R 85 1 12
HELIX 77 77 SER R 86 GLU R 88 5 3
HELIX 78 78 ARG R 91 ASP R 101 5 11
HELIX 79 79 ALA R 104 ALA R 117 1 14
HELIX 80 80 SER T 13 ARG T 25 1 13
HELIX 81 81 LYS T 28 LEU T 33 1 6
HELIX 82 82 LYS T 41 HIS T 60 1 20
HELIX 83 83 ALA T 89 GLY T 91 5 3
HELIX 84 84 THR U 39 LYS U 49 1 11
HELIX 85 85 ASN U 92 GLY U 97 1 6
HELIX 86 86 THR V 14 LYS V 18 5 5
HELIX 87 87 PRO V 49 GLN V 53 5 5
HELIX 88 88 GLY W 13 ALA W 23 1 11
HELIX 89 89 HIS W 44 GLN W 51 1 8
HELIX 90 90 ALA W 52 SER W 58 5 7
HELIX 91 91 GLY X 72 ASN X 75 5 4
HELIX 92 92 LYS Y 53 GLY Y 62 1 10
HELIX 93 93 GLY Y 62 ARG Y 71 1 10
HELIX 94 94 LEU Z 6 LYS Z 9 5 4
HELIX 95 95 SER Z 10 GLU Z 17 1 8
HELIX 96 96 ARG Z 23 LEU Z 28 1 6
HELIX 97 97 SER Z 40 GLN Z 45 1 6
HELIX 98 98 VAL Z 46 LEU Z 56 1 11
HELIX 99 99 LEU a 16 GLY a 27 1 12
HELIX 100 100 THR a 40 SER a 51 1 12
HELIX 101 101 LYS b 8 THR b 13 1 6
HELIX 102 102 SER c 10 ARG c 16 1 7
HELIX 103 103 VAL e 9 GLY e 17 1 9
HELIX 104 104 GLY e 17 ALA e 23 1 7
HELIX 105 105 THR e 24 GLY e 38 1 15
HELIX 106 106 ILE f 31 LYS f 35 5 5
HELIX 107 107 ALA f 36 HIS f 42 1 7
HELIX 108 108 ASP f 53 LEU f 61 1 9
HELIX 109 109 GLU g 30 LYS g 34 5 5
SHEET 1 A 5 GLN C 20 TYR C 21 0
SHEET 2 A 5 GLY C 221 VAL C 224 1 O ALA C 223 N TYR C 21
SHEET 3 A 5 ALA C 204 THR C 216 -1 N ILE C 214 O VAL C 222
SHEET 4 A 5 SER C 41 ILE C 50 -1 N ASN C 47 O LYS C 211
SHEET 5 A 5 ILE C 170 LYS C 177 -1 O ILE C 171 N VAL C 46
SHEET 1 B 2 ARG C 60 VAL C 64 0
SHEET 2 B 2 GLN C 160 ARG C 164 -1 O VAL C 161 N THR C 63
SHEET 1 C 3 LEU C 94 VAL C 95 0
SHEET 2 C 3 VAL C 75 PHE C 78 1 N VAL C 77 O LEU C 94
SHEET 3 C 3 VAL C 113 ALA C 116 1 O ILE C 115 N ALA C 76
SHEET 1 D 2 VAL D 2 LYS D 4 0
SHEET 2 D 2 VAL D 16 VAL D 18 -1 O LYS D 17 N VAL D 3
SHEET 1 E 2 LEU D 33 GLU D 34 0
SHEET 2 E 2 TYR D 61 ARG D 62 -1 O TYR D 61 N GLU D 34
SHEET 1 F 4 ARG D 100 LEU D 104 0
SHEET 2 F 4 ASN D 89 TYR D 95 -1 N VAL D 93 O ARG D 101
SHEET 3 F 4 ALA D 75 TYR D 82 -1 N ARG D 79 O LEU D 92
SHEET 4 F 4 GLN D 114 ILE D 115 -1 O ILE D 115 N ALA D 75
SHEET 1 G 4 GLN D 162 ASP D 167 0
SHEET 2 G 4 TYR D 170 ARG D 174 -1 O THR D 172 N ALA D 165
SHEET 3 G 4 MET D 180 GLU D 184 -1 O VAL D 183 N VAL D 171
SHEET 4 G 4 ILE D 266 ARG D 268 -1 O VAL D 267 N MET D 180
SHEET 1 H 7 LEU E 4 PHE E 15 0
SHEET 2 H 7 SER E 21 VAL E 29 -1 O VAL E 24 N THR E 12
SHEET 3 H 7 LEU E 186 LYS E 190 -1 O LEU E 187 N ILE E 27
SHEET 4 H 7 THR E 171 ASP E 181 -1 N ARG E 179 O LEU E 188
SHEET 5 H 7 LYS E 106 THR E 110 -1 N VAL E 109 O VAL E 172
SHEET 6 H 7 ASP E 200 PRO E 205 -1 O LYS E 204 N ASP E 108
SHEET 7 H 7 LEU E 4 PHE E 15 -1 N GLY E 6 O LEU E 201
SHEET 1 I 3 ARG E 33 VAL E 37 0
SHEET 2 I 3 ALA E 47 GLY E 53 -1 O GLN E 49 N GLN E 36
SHEET 3 I 3 GLY E 76 ARG E 83 -1 O ARG E 77 N THR E 52
SHEET 1 J 2 GLU F 2 LEU F 5 0
SHEET 2 J 2 SER F 10 THR F 13 -1 O LEU F 12 N LEU F 3
SHEET 1 K 4 LEU F 118 VAL F 120 0
SHEET 2 K 4 VAL F 186 MET F 188 1 O MET F 188 N ILE F 119
SHEET 3 K 4 VAL F 146 THR F 150 1 N ILE F 149 O VAL F 187
SHEET 4 K 4 VAL F 167 ASP F 171 1 O ASP F 168 N ILE F 148
SHEET 1 L 4 THR G 89 LEU G 90 0
SHEET 2 L 4 VAL G 30 LEU G 35 -1 N ILE G 33 O LEU G 90
SHEET 3 L 4 ILE G 153 THR G 157 -1 O THR G 156 N GLU G 31
SHEET 4 L 4 TYR G 127 SER G 128 -1 N TYR G 127 O ILE G 155
SHEET 1 M 3 ASP H 15 ILE H 18 0
SHEET 2 M 3 VAL H 22 LYS H 26 -1 O THR H 24 N LYS H 17
SHEET 3 M 3 THR H 33 LEU H 36 -1 O THR H 35 N ILE H 23
SHEET 1 N 2 VAL H 40 GLU H 41 0
SHEET 2 N 2 GLY H 52 PRO H 53 -1 O GLY H 52 N GLU H 41
SHEET 1 O 3 PHE H 82 THR H 83 0
SHEET 2 O 3 GLU H 129 GLY H 134 -1 O GLY H 134 N PHE H 82
SHEET 3 O 3 ILE H 120 THR H 126 -1 N THR H 121 O LYS H 133
SHEET 1 P 2 GLN H 87 VAL H 89 0
SHEET 2 P 2 GLY H 160 ARG H 162 -1 O ARG H 162 N GLN H 87
SHEET 1 Q 3 ARG H 94 LYS H 98 0
SHEET 2 Q 3 VAL H 101 SER H 105 -1 O VAL H 101 N LYS H 98
SHEET 3 Q 3 HIS H 114 GLN H 115 -1 O HIS H 114 N ILE H 102
SHEET 1 R 2 ILE I 4 LEU I 5 0
SHEET 2 R 2 ALA I 36 VAL I 37 -1 O VAL I 37 N ILE I 4
SHEET 1 S 5 LEU I 90 GLY I 92 0
SHEET 2 S 5 VAL I 78 ALA I 84 -1 N LYS I 83 O PHE I 91
SHEET 3 S 5 PHE I 139 VAL I 147 1 O VAL I 147 N SER I 82
SHEET 4 S 5 GLY I 126 GLN I 133 -1 N PHE I 132 O ALA I 140
SHEET 5 S 5 VAL I 115 ARG I 116 -1 N ARG I 116 O SER I 131
SHEET 1 T 3 VAL J 8 VAL J 12 0
SHEET 2 T 3 ILE J 54 TYR J 61 -1 O ILE J 54 N VAL J 12
SHEET 3 T 3 SER J 65 THR J 70 -1 O SER J 65 N TYR J 61
SHEET 1 U 2 GLY J 98 ILE J 100 0
SHEET 2 U 2 LEU J 137 VAL J 139 1 O VAL J 138 N GLY J 98
SHEET 1 V 4 LEU K 122 LYS K 123 0
SHEET 2 V 4 TYR K 53 VAL K 56 1 N VAL K 56 O LYS K 123
SHEET 3 V 4 TRP K 15 VAL K 18 1 N TYR K 16 O ILE K 55
SHEET 4 V 4 GLN K 138 VAL K 139 1 O GLN K 138 N VAL K 17
SHEET 1 W 2 VAL K 73 HIS K 76 0
SHEET 2 W 2 LYS K 85 THR K 88 -1 O LYS K 85 N HIS K 76
SHEET 1 X 6 MET L 7 VAL L 10 0
SHEET 2 X 6 ARG L 18 VAL L 24 -1 O VAL L 19 N LEU L 8
SHEET 3 X 6 ILE L 38 ILE L 43 -1 O LYS L 40 N LYS L 23
SHEET 4 X 6 ASP L 56 ARG L 64 -1 O LEU L 58 N ILE L 41
SHEET 5 X 6 ALA L 83 LEU L 87 -1 O VAL L 85 N VAL L 61
SHEET 6 X 6 MET L 7 VAL L 10 1 N ASN L 9 O CYS L 84
SHEET 1 Y 6 ILE L 77 PHE L 79 0
SHEET 2 Y 6 VAL Q 69 GLN Q 74 -1 O GLU Q 70 N ARG L 78
SHEET 3 Y 6 ALA Q 57 ARG Q 61 -1 N VAL Q 60 O ARG Q 71
SHEET 4 Y 6 LEU Q 39 ALA Q 48 -1 N ILE Q 47 O THR Q 59
SHEET 5 Y 6 THR Q 24 TRP Q 30 -1 N VAL Q 29 O GLN Q 40
SHEET 6 Y 6 VAL Q 80 ARG Q 87 -1 O SER Q 82 N LYS Q 28
SHEET 1 Z 3 THR M 74 ARG M 78 0
SHEET 2 Z 3 PHE M 107 ILE M 111 1 O ILE M 111 N ILE M 77
SHEET 3 Z 3 ARG M 126 VAL M 127 1 O ARG M 126 N VAL M 110
SHEET 1 AA 3 VAL M 89 VAL M 90 0
SHEET 2 AA 3 THR M 121 VAL M 122 1 O THR M 121 N VAL M 90
SHEET 3 AA 3 LYS M 141 ILE M 142 1 O LYS M 141 N VAL M 122
SHEET 1 AB 4 ILE N 63 ILE N 65 0
SHEET 2 AB 4 VAL N 101 MET N 105 -1 O GLU N 104 N TRP N 64
SHEET 3 AB 4 PHE N 31 LYS N 34 -1 N LEU N 33 O LEU N 102
SHEET 4 AB 4 THR N 129 THR N 132 -1 O THR N 129 N LYS N 34
SHEET 1 AC 3 GLY N 39 THR N 42 0
SHEET 2 AC 3 ASN N 88 ILE N 96 -1 O ALA N 94 N LEU N 41
SHEET 3 AC 3 LYS N 71 GLU N 75 -1 N ILE N 73 O GLU N 90
SHEET 1 AD 3 ILE O 33 THR O 37 0
SHEET 2 AD 3 MET O 110 LEU O 115 -1 O ALA O 111 N THR O 36
SHEET 3 AD 3 THR O 95 GLY O 101 -1 N ARG O 96 O GLU O 114
SHEET 1 AE 4 VAL P 47 SER P 52 0
SHEET 2 AE 4 ILE P 35 ILE P 40 -1 N VAL P 39 O LEU P 48
SHEET 3 AE 4 ARG P 25 ARG P 30 -1 N ARG P 25 O ILE P 40
SHEET 4 AE 4 SER P 91 PHE P 92 1 O SER P 91 N LEU P 26
SHEET 1 AF 2 GLY Q 89 ALA Q 90 0
SHEET 2 AF 2 LYS Q 110 GLU Q 111 -1 O LYS Q 110 N ALA Q 90
SHEET 1 AG 3 LYS S 10 SER S 15 0
SHEET 2 AG 3 TYR S 2 SER S 7 -1 N PHE S 5 O HIS S 12
SHEET 3 AG 3 VAL S 38 ALA S 42 -1 O ALA S 42 N TYR S 2
SHEET 1 AH 4 THR S 19 GLU S 23 0
SHEET 2 AH 4 TRP S 92 ILE S 98 -1 O THR S 94 N LEU S 22
SHEET 3 AH 4 ILE S 59 ARG S 68 -1 N GLY S 67 O PHE S 93
SHEET 4 AH 4 THR S 32 PHE S 35 -1 N VAL S 33 O ALA S 61
SHEET 1 AI 2 VAL S 72 ARG S 78 0
SHEET 2 AI 2 TYR S 83 HIS S 89 -1 O GLN S 87 N ILE S 74
SHEET 1 AJ 3 GLU T 2 ALA T 10 0
SHEET 2 AJ 3 SER T 101 SER T 108 -1 O VAL T 107 N THR T 3
SHEET 3 AJ 3 LYS T 70 GLU T 78 -1 N ASP T 77 O HIS T 102
SHEET 1 AK 2 MET T 82 PRO T 87 0
SHEET 2 AK 2 ALA T 93 LYS T 98 -1 O ASP T 94 N MET T 86
SHEET 1 AL 4 ALA U 13 PRO U 14 0
SHEET 2 AL 4 THR U 29 LYS U 33 -1 O LYS U 33 N ALA U 13
SHEET 3 AL 4 TRP U 80 GLU U 89 -1 O VAL U 85 N ILE U 30
SHEET 4 AL 4 GLU U 54 VAL U 63 -1 N GLU U 56 O THR U 86
SHEET 1 AM 2 VAL U 67 LYS U 68 0
SHEET 2 AM 2 GLY U 75 ARG U 76 -1 O GLY U 75 N LYS U 68
SHEET 1 AN 5 ILE V 64 GLN V 65 0
SHEET 2 AN 5 LYS V 32 VAL V 35 -1 N VAL V 33 O ILE V 64
SHEET 3 AN 5 ARG V 21 LEU V 28 -1 N ASN V 26 O ILE V 34
SHEET 4 AN 5 GLU V 9 VAL V 12 -1 N VAL V 10 O GLY V 22
SHEET 5 AN 5 VAL V 69 ILE V 71 -1 O ALA V 70 N ILE V 11
SHEET 1 AO 2 LEU V 40 GLN V 45 0
SHEET 2 AO 2 GLY V 56 GLU V 61 -1 O VAL V 58 N LYS V 43
SHEET 1 AP 7 THR W 3 VAL W 8 0
SHEET 2 AP 7 LEU W 38 ASP W 43 -1 O GLU W 41 N GLU W 7
SHEET 3 AP 7 LYS W 25 TYR W 31 -1 N ILE W 30 O LEU W 38
SHEET 4 AP 7 LEU W 86 ARG W 93 1 O ARG W 93 N TYR W 31
SHEET 5 AP 7 LYS W 71 ARG W 79 -1 N GLN W 78 O HIS W 88
SHEET 6 AP 7 LEU W 61 VAL W 64 -1 N LEU W 61 O VAL W 72
SHEET 7 AP 7 THR W 3 VAL W 8 1 N ILE W 4 O THR W 62
SHEET 1 AQ 3 LYS X 43 ALA X 46 0
SHEET 2 AQ 3 LYS X 77 GLU X 82 1 O ILE X 79 N PHE X 44
SHEET 3 AQ 3 LYS X 65 VAL X 70 -1 N LYS X 67 O SER X 80
SHEET 1 AR 2 ASN Y 15 ASN Y 16 0
SHEET 2 AR 2 THR Y 24 LYS Y 25 -1 O THR Y 24 N ASN Y 16
SHEET 1 AS 2 LEU Y 32 VAL Y 39 0
SHEET 2 AS 2 ARG Y 44 SER Y 51 -1 O VAL Y 46 N PHE Y 37
SHEET 1 AT 3 VAL a 35 GLU a 38 0
SHEET 2 AT 3 THR a 3 THR a 7 -1 N ILE a 6 O VAL a 35
SHEET 3 AT 3 LYS a 55 GLU a 57 -1 O GLU a 57 N LYS a 5
SHEET 1 AU 2 SER c 28 VAL c 29 0
SHEET 2 AU 2 LYS c 36 HIS c 37 -1 O HIS c 37 N SER c 28
SHEET 1 AV 3 PHE d 19 THR d 22 0
SHEET 2 AV 3 ILE d 8 SER d 12 -1 N LEU d 10 O TYR d 20
SHEET 3 AV 3 TYR d 48 LYS d 49 -1 O LYS d 49 N VAL d 11
SHEET 1 AW 2 LYS d 37 ASP d 39 0
SHEET 2 AW 2 GLN d 44 VAL d 46 -1 O VAL d 46 N LYS d 37
SHEET 1 AX 3 LYS f 14 LYS f 15 0
SHEET 2 AX 3 PHE f 21 HIS f 23 -1 O LYS f 22 N LYS f 14
SHEET 3 AX 3 ALA f 47 MET f 48 -1 O ALA f 47 N HIS f 23
SHEET 1 AY 2 CYS g 14 ARG g 19 0
SHEET 2 AY 2 VAL g 22 CYS g 27 -1 O ILE g 26 N LYS g 15
LINK O3' U B 744 P 1MG B 745 1555 1555 1.62
LINK O3' 1MG B 745 P PSU B 746 1555 1555 1.61
LINK O3' PSU B 746 P 5MU B 747 1555 1555 1.63
LINK O3' 5MU B 747 P G B 748 1555 1555 1.60
LINK O3' G B 954 P PSU B 955 1555 1555 1.60
LINK O3' PSU B 955 P G B 956 1555 1555 1.62
LINK O3' C B1617 P 6MZ B1618 1555 1555 1.61
LINK O3' U B1834 P 2MG B1835 1555 1555 1.61
LINK O3' 2MG B1835 P C B1836 1555 1555 1.60
LINK O3' G B1910 P PSU B1911 1555 1555 1.62
LINK O3' PSU B1911 P A B1912 1555 1555 1.62
LINK O3' A B1916 P PSU B1917 1555 1555 1.62
LINK O3' PSU B1917 P A B1918 1555 1555 1.62
LINK O3' A B1938 P 5MU B1939 1555 1555 1.62
LINK O3' 5MU B1939 P U B1940 1555 1555 1.59
LINK O3' C B1961 P 5MC B1962 1555 1555 1.61
LINK O3' 5MC B1962 P U B1963 1555 1555 1.59
LINK O3' G B2029 P 6MZ B2030 1555 1555 1.62
LINK O3' U B2068 P 7MG B2069 1555 1555 1.62
LINK O3' 7MG B2069 P A B2070 1555 1555 1.61
LINK O3' G B2250 P OMG B2251 1555 1555 1.62
LINK O3' OMG B2251 P G B2252 1555 1555 1.62
LINK O3' G B2444 P 2MG B2445 1555 1555 1.63
LINK O3' 2MG B2445 P G B2446 1555 1555 1.61
LINK O3' A B2448 P H2U B2449 1555 1555 1.63
LINK O3' H2U B2449 P A B2450 1555 1555 1.61
LINK O3' C B2456 P PSU B2457 1555 1555 1.61
LINK O3' PSU B2457 P G B2458 1555 1555 1.61
LINK O3' A B2497 P OMC B2498 1555 1555 1.61
LINK O3' OMC B2498 P C B2499 1555 1555 1.62
LINK O3' G B2502 P 2MA B2503 1555 1555 1.61
LINK O3' 2MA B2503 P PSU B2504 1555 1555 1.62
LINK O3' PSU B2504 P G B2505 1555 1555 1.63
LINK O3' C B2551 P OMU B2552 1555 1555 1.59
LINK O3' OMU B2552 P G B2553 1555 1555 1.61
LINK O3' G B2574 P CH B2575 1555 1555 1.61
LINK O3' CH B2575 P G B2576 1555 1555 1.62
LINK O3' C B2579 P PSU B2580 1555 1555 1.61
LINK O3' PSU B2580 P G B2581 1555 1555 1.61
LINK O3' U B2604 P PSU B2605 1555 1555 1.62
LINK O3' PSU B2605 P C B2606 1555 1555 1.62
LINK O3' C B1914 P 3TD B1915 1555 1555 1.62
LINK O3' 3TD B1915 P A B1916 1555 1555 1.62
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
