#=GF ID   DsrD
#=GF AC   PF08679.6
#=GF DE   Dissimilatory sulfite reductase D (DsrD)
#=GF AU   Mistry J
#=GF SE   pdb_1ucr
#=GF GA   24.20 24.20;
#=GF TC   24.50 49.10;
#=GF NC   24.10 24.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12962631
#=GF RT   Crystal structure of dissimilatory sulfite reductase D (DsrD)
#=GF RT   protein--possible interaction with B- and Z-DNA by its
#=GF RT   winged-helix motif. 
#=GF RA   Mizuno N, Voordouw G, Miki K, Sarai A, Higuchi Y; 
#=GF RL   Structure. 2003;11:1133-1140.
#=GF DR   INTERPRO; IPR014793;
#=GF DR   SCOP; 1ucr; fa;
#=GF CC   The structure of the DsrD protein has shown it to contain a
#=GF CC   winged-helix motif similar to those found in DNA binding
#=GF CC   proteins [1].  The structure suggests a possible role for DsrD
#=GF CC   in transcription of translation of genes which catalyse
#=GF CC   dissimilatory sulfite reduction.
#=GF SQ   56
#=GS F0JJB5_DESDE/7-73     AC F0JJB5.1
#=GS D9YAD8_9DELT/3-69     AC D9YAD8.1
#=GS B1I6N8_DESAP/3-72     AC B1I6N8.1
#=GS D2RFY8_ARCPA/9-69     AC D2RFY8.1
#=GS G7Q7L8_9DELT/3-68     AC G7Q7L8.1
#=GS Q9AIK3_BILWA/405-474  AC Q9AIK3.1
#=GS E6VZA5_DESAO/7-73     AC E6VZA5.1
#=GS C8WZS3_DESRD/5-70     AC C8WZS3.1
#=GS E5Y7F1_BILWA/405-474  AC E5Y7F1.1
#=GS G6IJ37_9DELT/11-77    AC G6IJ37.1
#=GS B8FME1_DESAA/5-70     AC B8FME1.1
#=GS B6WUZ3_9DELT/3-69     AC B6WUZ3.1
#=GS Q9ZH16_DESTE/23-91    AC Q9ZH16.1
#=GS B8DRW4_DESVM/3-69     AC B8DRW4.1
#=GS A8ZX95_DESOH/8-73     AC A8ZX95.1
#=GS D6SSJ6_9DELT/5-71     AC D6SSJ6.1
#=GS C8W1Z0_DESAS/3-71     AC C8W1Z0.1
#=GS G1V1V9_9DELT/405-474  AC G1V1V9.1
#=GS F2KRS6_ARCVS/9-69     AC F2KRS6.1
#=GS Q9ACL4_9DELT/4-68     AC Q9ACL4.1
#=GS G7Q9G1_9DELT/3-68     AC G7Q9G1.1
#=GS E1K133_DESFR/3-68     AC E1K133.1
#=GS G6I4R0_9FIRM/3-71     AC G6I4R0.1
#=GS DSRD_ARCFU/7-67       AC P70742.2
#=GS C6BZ31_DESAD/7-73     AC C6BZ31.1
#=GS C9RA40_AMMDK/7-75     AC C9RA40.1
#=GS F8AAL3_THEID/5-71     AC F8AAL3.1
#=GS F3YZL2_DESAF/7-73     AC F3YZL2.1
#=GS E3IP58_DESVR/3-69     AC E3IP58.1
#=GS E8RE38_DESPD/7-71     AC E8RE38.1
#=GS Q1NLA7_9DELT/7-71     AC Q1NLA7.1
#=GS Q315R7_DESDG/2-68     AC Q315R7.1
#=GS F6CRI1_DESK7/3-71     AC F6CRI1.1
#=GS D6Z6Q0_DESAT/7-71     AC D6Z6Q0.1
#=GS E1YFB0_9DELT/5-70     AC E1YFB0.1
#=GS C8X3C4_DESRD/5-70     AC C8X3C4.1
#=GS B8IZ99_DESDA/3-67     AC B8IZ99.1
#=GS Q2RI34_MOOTA/4-72     AC Q2RI34.1
#=GS B6WV00_9DELT/3-69     AC B6WV00.1
#=GS Q9K5B7_9DELT/7-71     AC Q9K5B7.1
#=GS B8J4Q8_DESDA/3-69     AC B8J4Q8.1
#=GS G1UUT1_9DELT/3-69     AC G1UUT1.1
#=GS DSVD_DESVH/3-69       AC Q46582.1
#=GS DSVD_DESVH/3-69       DR PDB; 1WQ2 B; 3-68;
#=GS DSVD_DESVH/3-69       DR PDB; 1UCR B; 3-69;
#=GS DSVD_DESVH/3-69       DR PDB; 1UCR A; 3-69;
#=GS DSVD_DESVH/3-69       DR PDB; 1WQ2 A; 3-69;
#=GS Q9K5B3_9DELT/11-77    AC Q9K5B3.1
#=GS E1QFJ1_DESB2/3-70     AC E1QFJ1.1
#=GS F8C2Z5_THESO/5-73     AC F8C2Z5.1
#=GS G2H7S3_9DELT/3-69     AC G2H7S3.1
#=GS Q6AQ45_DESPS/7-71     AC Q6AQ45.1
#=GS C0QD62_DESAH/10-76    AC C0QD62.1
#=GS O93652_ARCPR/9-69     AC O93652.1
#=GS A0LQK5_SYNFM/4-68     AC A0LQK5.1
#=GS Q8RKE4_9DELT/10-76    AC Q8RKE4.1
#=GS A1VGI0_DESVV/3-69     AC A1VGI0.1
#=GS D8F2V1_9DELT/3-71     AC D8F2V1.1
#=GS C7LUX4_DESBD/3-69     AC C7LUX4.1
#=GS C4XH85_DESMR/3-68     AC C4XH85.1
F0JJB5_DESDE/7-73                ...a-AKAEIIKFCE...EKSSSKTKFYFNDFTKL....FPDEKSRDVKKLLTQLVQEEKMVFWSSGSTTMYGLAGV-g.
D9YAD8_9DELT/3-69                ....DDKEIVVEFLK...SKSAAKSKFYFKDFLEL....FPDRGPRDVKKVLTKLINEEVLEFWSSGSTSMYGLKGAG..
B1I6N8_DESAP/3-72                ....DLKQAIVEYLQ...-SGKTKTKFYFNEIDKAvkdkIPSAKTLQVKKACSALINEGVLEYYSTGSTTMYGLKGAG..
D2RFY8_ARCPA/9-69                ....ELKQKVIEYLQ...-----KKPWQVRDLAK-....ILRVKKKELDKIVQELINEGKAAYWSSGSTTYITTPEK-l.
G7Q7L8_9DELT/3-68                ..se--KEQVLEFLT...-GKTGKSKFYFSDFCKI....FPDKKQREVKKVLTELVNEGKLEFWSSGSTTMYGMTGAG..
Q9AIK3_BILWA/405-474             ....EDKEIVVNFLKdkmSRPGAKTKYYFKDFLEL....FPTKGTRDVKNVLSVLVSEESLEYWSSGSTTMYGLKGAG..
E6VZA5_DESAO/7-73                ...a-AKAEILKFCE...EKSASKSKFYFNDFTKL....FPDEKTRDVKKLLTQLVQEEKMVFWSSGSTTMYGLAGA-g.
C8WZS3_DESRD/5-70                ....EIKQKILDELK...AKSKNKSKFYFSDLQK-....MTGMKPREAKKIINVMVTDGDLVYWSSGSTTMYSLPGAG..
E5Y7F1_BILWA/405-474             ....EDKEIVINFLKdkmSRPGAKTKYYFKDFLEL....FPAKGTRDVKNVLSVLVSEESLEYWSSGSTTMYGLKGAG..
G6IJ37_9DELT/11-77               ...g-AEKAVIDWLQ...GKAGSKTKFYIKDFYKL....FPDDKPREIKKVVNKMVENGILEYWSSGSTTMYGLKGAG..
B8FME1_DESAA/5-70                ...a-ARDTIVEKLK...-GKKGKSKFYLKDFYAM....FPEEKPRTVKKLVNTMVSEGTLEYWSSGSTTLIGLKGV-g.
B6WUZ3_9DELT/3-69                ....DEKDIIVEFLK...GKSASKSKFYFKDFTEL....FPDKGPREVKKILTKLVNEEVLEFWSSGSTTMYGLKGAG..
Q9ZH16_DESTE/23-91               ....EIKKAIIEF--...ASNSKKTRFYFKDMEKAvqekIPTAKAREIKKAASELVNEGTLIYFSTGSTTMYGLKERC..
B8DRW4_DESVM/3-69                ....EAKNKVVEFLQ...SKAGSKSKFYFNDFLDL....FPDKGPRDVKKILTALVNAEVLEYWSSGSTTMYGLKGAG..
A8ZX95_DESOH/8-73                ...t-ANKMVIEALQ...KKQKTKSKFYFSDLQD-....ILGLKPREAKKFVNKMVEAQILEFWSSGSTTMYGLKGTG..
D6SSJ6_9DELT/5-71                ...a-AKQEIINFLE...SKSGSKTKFYFNDFTKI....FPDMKAREVKKLLSELVQEEKLVYWSSGSTTMYGMKGAG..
C8W1Z0_DESAS/3-71                ....EIKKAILEF--...AETSKKTKFYFKDMEKAiqkvLPDAKARDIKKAASALVNEEVLIYFSTGSSTMYGLKGRG..
G1V1V9_9DELT/405-474             ....EDKEIVINFLKdkmSRPGAKTKYYFKDFLEL....FPAKGTRDVKNVLSVLVSEESLEYWSSGSTTMYGLKGAG..
F2KRS6_ARCVS/9-69                ....EDKQKVLEKLG...-----QKTWKIKDLAK-....ILKMDKKVVQKIVMDLIDEGKAAYWSSGSTTYYSTPE--yi
Q9ACL4_9DELT/4-68                ....EAKQKILDW--...MKQQKKTKHYFNDLCKA....VPELSMRQAKKIINELVSEGKLRYWTSGSTTMYMLPG--vd
G7Q9G1_9DELT/3-68                ..se--KEQVLEFLT...-GKTGKSKFYFSDFCKI....FPDKKQREVKKVLTELVNEGKLEFWSSGSTTMYGMTGAG..
E1K133_DESFR/3-68                ..se--KEQVLEFLT...-GKTGKSKFYFNDFCKI....FPDKKPREVKKVLTELVNEGKVIFWSSGSTSMYGLAGV-g.
G6I4R0_9FIRM/3-71                ....EMKKIIVEF--...AETSKKTKFYFKDIEKAvqkvNPDAKAREIKKACTALINDGTMIYFSTGSSTMYGLKGRG..
DSRD_ARCFU/7-67                  ....EDKQKVLAQLS...-----KKTWKIPELAK-....ILKMDKKVVKKIVQDLINEGVAGYWSSGSTTYVATKE--yi
C6BZ31_DESAD/7-73                ...s-AKVEILDFLE...KKTGAKSKFYFNDFTKL....FPDAKGREVKKVLTALVKEEKIEYWSSGSTTMYGLTGAG..
C9RA40_AMMDK/7-75                ....DIKNAIVEYLT...--NAKKSKHYFKDIEKAvkqkFPDASTRDIKKACNELVNEDKVAYFSTGSTTMYCLKGR-e.
F8AAL3_THEID/5-71                ....EVKQKILEFME...KKAKSKSKIYLKDMQRA....IPDAKPMLIKKAANQLVQEGKLEYFSTGSTVMYSLPGQ-d.
F3YZL2_DESAF/7-73                ...t-AKDEVLKFLE...EKREKKTKFYFNDFTAL....FPDGKPREVKKILSDLVKEEKLEYWSSGSTTMYGLKGAG..
E3IP58_DESVR/3-69                ....EAKQKVVDFLN...SKSGSKSKFYFNDFTDL....FPDMKQREVKKILTALVNDEVLEYWSSGSTTMYGLKGAG..
E8RE38_DESPD/7-71                ....DLKKAIIEK--...AKKSPKPQLYIKDFYEC....DPDAKPRDIKKVANALVTEGELMFWSSGSTTMYARPDR-i.
Q1NLA7_9DELT/7-71                ....DLKEKIMEK--...ALNGPKSQLYVKDFFAC....DPEAKPRAVKNAANDLVKEGRLVFWSSGSTTMYAAKERG..
Q315R7_DESDG/2-68                ....DDKQIIVDFIE...SKSKSKSKFYFNDFLPL....FPDMKPREVKKILTKLVNEEVLEFWSSGSTTMYGMKGAG..
F6CRI1_DESK7/3-71                ....EIKKAILEF--...ASASKKTRFYFKDMEKAvqekVPGAKAREIKKAASELINEGTLIYFSTGSTTMYGLKDRC..
D6Z6Q0_DESAT/7-71                ....ELKEKIMEK--...ALKGPKTQLYVKDFYAC....DPEAKPRAVKNAANDLVKEGRMVFWSSGSTTMYAAKER-a.
E1YFB0_9DELT/5-70                ...a-LKKTIVETLE...-GKKGKSKFYLKDFYAM....APDEKPRAVKNLVNKMVTEGTLEYWSSGSTTLIGLKG--ig
C8X3C4_DESRD/5-70                ...e-AKDKLEAELQ...KKSSNKSKFYFNDLAK-....ILDEKPRQAKKVVTEMVNEGRLSLWSSGSTTMYTLPGQG..
B8IZ99_DESDA/3-67                ..pd--QQLIVDF--...ISTKNKTKFYFKDFLEI....FPDKGPREVKKLLTAMVQSEIMEFWSSGSTTMYGLKGAG..
Q2RI34_MOOTA/4-72                ....DIKAAILDF--...AANSKKSKFYFKDLEKAvqakIPDAKAREIKKAATELVNEEKLIYFSTGSTTMYGLKGRG..
B6WV00_9DELT/3-69                ...d-EKDVVVEFLK...SKSSSKSKFYFKDFTDL....FPDKGPREVKKILTKLVNEEVLEFWSSGSTTMYGLKGAG..
Q9K5B7_9DELT/7-71                ....ELEAAIIEK--...AKKSPKPQLYIKDFYAC....DPDAKPREIKKVANALVTKGELMFWSSGSTTMYARPDR-i.
B8J4Q8_DESDA/3-69                ....DDKDIVVDFLN...SKAASKSKFYFKDFTDL....FPDKGPRDVKKILTKLVNEEVLEFWSSGSTTMYGLKGAG..
G1UUT1_9DELT/3-69                ....DDKEIVVEFLK...SKSAAKSKFYFKDFLEL....FPDRGPRDVKKVLTKLINEEVLEFWSSGSTSMYGLKGAG..
DSVD_DESVH/3-69                  ....EAKQKVVDFLN...SKSGSKSKFYFNDFTDL....FPDMKQREVKKILTALVNDEVLEYWSSGSTTMYGLKGAG..
#=GR DSVD_DESVH/3-69       SS    ....HHHHHHHHHHS...SCCCHSS-EEHHHHHHH....-TTS-HHHHHHHHHHHHHTTSEEEEEETTEEEEEETTHH..
Q9K5B3_9DELT/11-77               ...a-AQKAVVDWLE...KKAGSKTKFYIKDFYKI....FPDDKPREIKKVVNKMVENEILEFWSSGSTTMYGLKGAG..
E1QFJ1_DESB2/3-70                dvrs----LVLEV--...-MTKKKKRMMMNDLLKEvqklDESVDKKSLKKETTAMIADGTLSYWSSGSTTYFDMPGN-e.
F8C2Z5_THESO/5-73                ....ELKQKILQVIEe.kVKKGGKSKVYLKDIQRE....LPDVSPRDIKNAANELVREGKLEYFSSGSTVLFGIPGV-g.
G2H7S3_9DELT/3-69                ....EAKNKVVEFLQ...SKAGSKSKFYFNDFLDL....FPDKGPRDVKKILTALVNAEVLEYWSSGSTTMYGLKGAG..
Q6AQ45_DESPS/7-71                ....ELKNVIVEK--...AQKSPKPQLYIKDFYKC....DPETKPRVMKNICNELVREQRLMFWSSGSTTMYGVPER-i.
C0QD62_DESAH/10-76               ....EAEKAIMAWLE...KKTKSKSKFYLKDFYSI....FPDDKPRMIKKVVNNMVTEGVLEYWSSGSTTMYGIKGAG..
O93652_ARCPR/9-69                ....ELKQKVIEYLQ...-----KKPWQVRDLAK-....ILRVKKKELDKIVQELINEGKAAYWSSGSTTYITTPEK-l.
A0LQK5_SYNFM/4-68                ....DAKQRIIEW--...VKEQKKTKHYFNDLCKA....VPEIKMMQAKKIINELVAEGKLKYWSSGSTTMYMLPIE-g.
Q8RKE4_9DELT/10-76               ...a-ATKAVVDWLT...KKAKTKSKFYIKDFYKI....FPDDKPRAIKKVVNKMVETGELEFWSSGSTTMYGLKG--gg
A1VGI0_DESVV/3-69                ....EAKQKVVDFLN...SKSGSKSKFYFNDFTDL....FPDMKQREVKKILTALVNDEVLEYWSSGSTTMYGLKGAG..
D8F2V1_9DELT/3-71                ....DMKQAILDF--...AEKSKKSKFYFNDIQKAvqkvLPDAKARMIKKAATALINEEKLIYFSTGSSTMYGLKGRG..
C7LUX4_DESBD/3-69                ...d-PKEIVLEFIQ...SKSKQKSKFYFNDLAAL....FPDMKMREAKKVINQLVSEGVLEYWSSGSTTMYGVPGAG..
C4XH85_DESMR/3-68                ..se--KEQVLEFLT...-GKTGKSKFYFSDFCKI....FPDKKQREVKKILTELVNEGKLEFWSSGSTTMYGMTGAG..
#=GC SS_cons                     ....HHHHHHHHHHS...SCCCHSS-EEHHHHHHH....-TTS-HHHHHHHHHHHHHTTSEEEEEETTEEEEEETTHH..
#=GC seq_cons                    ....-hKptll-aLp...tcsssKoKFYFpDFtch....hPDtKsR-lKKllspLVsEtpLpYWSSGSTTMYGLKGsG..
//