#=GF ID FadA
#=GF AC PF09403.14
#=GF DE Adhesion protein FadA
#=GF AU Mistry J;0000-0003-2479-5322
#=GF SE pdb_2avr
#=GF GA 28.50 28.50;
#=GF TC 28.50 29.70;
#=GF NC 28.20 25.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Coiled-coil
#=GF CL CL0590
#=GF RN [1]
#=GF RM 16030227
#=GF RT Identification and characterization of a novel adhesin unique to
#=GF RT oral fusobacteria.
#=GF RA Han YW, Ikegami A, Rajanna C, Kawsar HI, Zhou Y, Li M, Sojar HT,
#=GF RA Genco RJ, Kuramitsu HK, Deng CX;
#=GF RL J Bacteriol. 2005;187:5330-5340.
#=GF RN [2]
#=GF RM 18996848
#=GF RT Crystal structure of FadA adhesin from Fusobacterium nucleatum
#=GF RT reveals a novel oligomerization motif, the leucine chain.
#=GF RA Nithianantham S, Xu M, Yamada M, Ikegami A, Shoham M, Han YW;
#=GF RL J Biol Chem. 2009;284:3865-3872.
#=GF DR INTERPRO; IPR018543;
#=GF DR SO; 0001080; coiled_coil;
#=GF CC FadA (Fusobacterium adhesin A) is an adhesin which forms two
#=GF CC alpha helices that form an intra-molecular coiled-coil
#=GF CC arrangement.
#=GF SQ 39
#=GS U2RGR3_9FUSO/25-123 AC U2RGR3.1
#=GS W4K504_HETIT/139-237 AC W4K504.1
#=GS C7NB18_LEPBD/29-127 AC C7NB18.1
#=GS A0A8I2YHS4_9AGAM/465-563 AC A0A8I2YHS4.1
#=GS C6JLX7_FUSVA/28-126 AC C6JLX7.1
#=GS U2RF02_9FUSO/29-127 AC U2RF02.1
#=GS C6JN14_FUSVA/25-120 AC C6JN14.1
#=GS A0A8E2DJE0_9APHY/494-599 AC A0A8E2DJE0.1
#=GS S8FTH2_FOMPI/508-597 AC S8FTH2.1
#=GS D1AP26_SEBTE/38-136 AC D1AP26.1
#=GS M2PMS2_CERS8/490-579 AC M2PMS2.1
#=GS D1AGZ5_SEBTE/21-119 AC D1AGZ5.1
#=GS C6JQX2_FUSVA/28-126 AC C6JQX2.1
#=GS Q8RGM7_FUSNN/28-126 AC Q8RGM7.1
#=GS A0A8H7KY78_9AGAM/526-624 AC A0A8H7KY78.1
#=GS C9N0R7_9FUSO/35-133 AC C9N0R7.1
#=GS C9N0R8_9FUSO/36-134 AC C9N0R8.1
#=GS U2ST02_9FUSO/42-140 AC U2ST02.1
#=GS U2RGJ3_9FUSO/30-90 AC U2RGJ3.1
#=GS A0A166AI43_9AGAM/509-607 AC A0A166AI43.1
#=GS D0GM93_9FUSO/1-95 AC D0GM93.1
#=GS Q8RIP2_FUSNN/25-123 AC Q8RIP2.1
#=GS D0GMC2_9FUSO/28-126 AC D0GMC2.1
#=GS C6JLX6_FUSVA/32-130 AC C6JLX6.1
#=GS A0A8H7KRH8_9AGAM/529-627 AC A0A8H7KRH8.1
#=GS A0A4S4LU99_9AGAM/1075-1173 AC A0A4S4LU99.1
#=GS C7NCH6_LEPBD/42-141 AC C7NCH6.1
#=GS A0A286UGD1_9AGAM/430-529 AC A0A286UGD1.1
#=GS U2RFK0_9FUSO/1-93 AC U2RFK0.1
#=GS U2T0T5_9FUSO/29-114 AC U2T0T5.1
#=GS D1AP27_SEBTE/27-125 AC D1AP27.1
#=GS C9MXJ4_9FUSO/29-127 AC C9MXJ4.1
#=GS C7NCH5_LEPBD/35-133 AC C7NCH5.1
#=GS D1AFH3_SEBTE/19-117 AC D1AFH3.1
#=GS Q8R6K0_FUSNN/20-118 AC Q8R6K0.1
#=GS D1AQ16_SEBTE/21-119 AC D1AQ16.1
#=GS D0GMC3_9FUSO/33-131 AC D0GMC3.1
#=GS C6JJE9_FUSVA/26-121 AC C6JJE9.1
#=GS U2QXW1_9FUSO/35-133 AC U2QXW1.1
U2RGR3_9FUSO/25-123 .............KYNQLESQFTNLVNLENQQ.......YAKLRANAEVASRKLDERQRLKAALEDRIAKIEG.SAGAKFFKGEYGDLVKEYKNVVKALDEEIKSLSKTVENYQAVESLK....
W4K504_HETIT/139-237 .............QLQALESKIQELQTSQEQA.......LKKEREASQRMAVSVQKHKMAEDALRAEIEQLTSeLTDAERYQEAYQSLIEEVEALAARNE-LAEDEAERLSKFNAEI---lgh.
C7NB18_LEPBD/29-127 .............SLDSIENQFNELVKKEEAQk....eaYRKQKEQLEAEIEDLKAKNEGRDKLIEKLKV---.DSEVRWHRDKYKNILHNVNTFYKKINKSIAEKEQKVAELDALLSVM....
A0A8I2YHS4_9AGAM/465-563 ............n-ANALEKQLGEQASQHKAA.......LQKERDVAQKLSMQLRMSKTAEDALKAEMEQLNVeLTEVSRFQDAYYKLLDETEGLLARND-LAEEEAERLSQFNAE----ilgh
C6JLX7_FUSVA/28-126 .............RFNTLEQEYKMLMQKEDER.......YNSEKQIAETAKATLAKQRELYNQISTKAGKLGQ.IKDVKFYKEQYGELAKKYQDALKELEGQMKEQESIINRFQQLQAVK....
U2RF02_9FUSO/29-127 .............SLNSIENKFNDLLEKEAQKk....reFEVQKAQLENEVADLKAKEEGKEKLFEKLKK---.DSEVRWHRDKYKQVLNNYDTYYKNLAKLIKEKEQKIAELEQILAIM....
C6JN14_FUSVA/25-120 ............t-LEQLELNLQQLEAEERAM.......YNQRKAEAEEAEKTLEAQRKMYAEISEKEKRILS.VKDNKFYKGQYQELAKKYGEAKKELEADMRKQEEIISIFEAIK---....
A0A8E2DJE0_9APHY/494-599 ......qtqavak-------QLDEMRAQTKAEvaiaeqsLQREKEAAQRLAATLQKSRIAEEALRDEIQKLIEdLEEADRYRDAYNSLVEEVDALVARNA-LAEDEAQRLSKFNAE----ilgh
S8FTH2_FOMPI/508-597 ......aaerara----------------QQG.......LQKEKDAARRLANTVQQHRAAEDALRDEMDQMSAeLADAERYREAYGQLVEEVDALVARNA-LAEEEASKLSKFNAE----ivgh
D1AP26_SEBTE/38-136 .............RYDAISNQLDALRAKDDQR.......FQLEQQKADNAQAELDKQVEMRDELQAKYEEAAQ.LAKISYYKNTYGPVANQYKDLLGKLDSSIKENQKIIDNFEKLSAA-r...
M2PMS2_CERS8/490-579 ........eaeva--------------KVEQN.......LQREKEAAQRLSATLQKSRIAEEALREEIQKLMEaLEEAERYRDAYSSLAEEVEALVARNA-LAEDEAQRLSRFNAE----ivgh
D1AGZ5_SEBTE/21-119 .............RMSTITDEVEKINKAESVRt....erVMKRKAKLEKELADLYKNYNSRTEMTEKLRM---.DSEVRWYRDEYKEILKKYDTVQTELEKEIEKREKELAVINSGLNLM....
C6JQX2_FUSVA/28-126 .............QMKSLEKEYQLLLKKEDQR.......YAQEKQIAETAEKTLAEQKNLYKSVAGSLSQLQQ.MEKYIFYKDDYNQLLNKYQTILKDLEKSMNNQQVIIDNFKQIQL--ek..
Q8RGM7_FUSNN/28-126 ............e-LQALDAEYQNLANQEEAR.......FNEERAQADAARQALAQNEQVYNELSQRAQRLQA.EANTRFYKSQYQDLASKYEDALKKLESEMEQQKAIISDFEKIQALR....
A0A8H7KY78_9AGAM/526-624 ............q-IARLEGEMREATVKNTEA.......LRVERQIAQRASSAAQVVKMSEEGLRAEVEQLTAeLTEAERYQEAYHSLVEEVGQLMDRND-LAEEEAERLSQFNAE----iigh
C9N0R7_9FUSO/35-133 .............RFNQLEAEYERLVNMENQE.......YNKLKANADAAASKLAEKEAQKAQLEERISKVEA.ASETKAFKAQYAELAKQYKAVAKSLDTEIKSLRATVENFAAIEALK....
C9N0R8_9FUSO/36-134 .............SLNNLENQLSRLQQMEDAK.......FREQEAQANAAVQRLNNYTAMQAKIDQRIAEIEA.NAETSIFGKEFKSKIAEYKNLRNQLDKEIAREQQAIDNYELIKSLR....
U2ST02_9FUSO/42-140 .............SLNSIENKFNDLLEKEAQKk....reFEVQKAQLENEVADLKAKEEGKEKLFEKLKK---.DSEVRWHRDKYKQILNNYDTYYKNLAKLIREKEQKIAELEQILAIM....
U2RGJ3_9FUSO/30-90 .............SLNSIENKFNDLLEKEAQKk....reFEAQKAQLESEVADLKAKEEGKEKLFEKLKK---.DSEVRWHR--------------------------------------....
A0A166AI43_9AGAM/509-607 .............RIAALEVQMQEAGAKHTEA.......LRVEKQIAQRAGATAQVVKMSEEGLKAEVEQLTTeLTDAERYQEAYHGLVEEVGQLMDRND-LAEDEAERLSAFNAE----ilgh
D0GM93_9FUSO/1-95 .............----IEAKFNDLLEKEAQKk....reFEAQKAQLEAEVEDLKAKEQGKEKLFEKLKK---.DSEVRWLRDKYKQVLNNYDTYYKNIAKMIREKEQKISELEAMLSVM....
Q8RIP2_FUSNN/25-123 ............e-LKGLNAEYENLVKEEEAR.......FQKEKELSERAAAQNVKLAELKASIEEKLLAAPE.ERKTKFFKDTFDGLVKDYSKYLSQINEKIAENTEIVSNFEKIQKIR....
D0GMC2_9FUSO/28-126 .............KFNKLEAEYNQLVNMENQQ.......YSKLRANAENASQQLQEKQALKAAIEEKMSKLEQ.TRNTKYFKGEYENLVKEYKNVVKALDADIAGLSKVVDNFNKVEELK....
C6JLX6_FUSVA/32-130 .............RFSQLEAELKMLEQKENER.......FKEEEQIAKSAQNNLNVLTNLKNKCEERINYMTT.MEGRSIYSNEMKNLLKQYQGFLGEIDKQSKVEERKIFEFNQLKSLR....
A0A8H7KRH8_9AGAM/529-627 ............q-IARLEGEMREAIVKNTEA.......LRVERQIAQRASSAAQVVKMSEEGLRAEVEQLTAeLTEAERYQEAYHSLVEEVGQLMDRND-LAEEEAERLSQFNAE----iigh
A0A4S4LU99_9AGAM/1075-1173 .............QLQALDSKIQENKAAHEQA.......LKKERETTQRLATSVQKHKMAEEALRAEIEQLTTeLTDAERYQEAYQNLVEEVEALAARNE-LAEDEAQRLSRFNAE----ilgh
C7NCH6_LEPBD/42-141 .............RFNQLEAELERLINMEDQE.......YNKLKATAESAAERLAEKSAQKAQIEEKIAKIEAsASNTKSFKAQYGDIIKQYKAVVKSLDAEIRSLTTTVDNFAAIESVK....
A0A286UGD1_9AGAM/430-529 nalaaaearvlee------------VQKKEEL.......LRKEREITSNMQATVQKGKMAEEALKAEIEQLMTeLADVEDYREAYQTIAEEMRGLVARNA-LAEDEATRLSEFNAE----ilsh
U2RFK0_9FUSO/1-93 .............------NKFNDLLEKEAQKk....reFEAQKSQLETEVADLKAKEEGKEKLFEKLKK---.DSEVRWHRDKYKQILNNYDIYYKNLAKLIREKEQKIFELEQILAIM....
U2T0T5_9FUSO/29-114 .............SLNSIENKFNDLLEKEAQKk....reFEAQKAQLESEVADLKAKEEGKEKLFEKLKK---.DSEVRWYRDKYKQVLNNYDTYYKNLAKLIKEKE-------------....
D1AP27_SEBTE/27-125 ............q-AAAIDQQIQVIENRTSQT.......LAAEQQKAEVATDNVAKYSELLENVQDQLDVVAG.ERKVSFYEKEYQGVISSLTSLRNDLQKSITANQKVVDAYEEFSAI-v...
C9MXJ4_9FUSO/29-127 .............SLDSIDSQYEELLRKEEAQk....esYRNQKAQLEAELEKLKAQQTDKEKIVEKLRV---.DSEVRWHRDKYRKILKYNESNFKNLNKSIAEKEQKIAELDTLLSIM....
C7NCH5_LEPBD/35-133 .............SLSNLENQLDRLQQLEEAK.......YKEQEALAESAAQKLNSYTQMQAKIDERIAQIEA.VTDSSIFSKEFKTKVSEYKALRNQLDKEIARQQQIIDNFEISKSLR....
D1AFH3_SEBTE/19-117 .............RMSTLTEEAGKINSAETARq....erLQRRKEKLENDLEKLYKNYDSRAEITEKLRV---.DSEVRWYRDEYREILKKYDDVQNNLNEEISKKEKELALVNIGLGI-q...
Q8R6K0_FUSNN/20-118 ............e-VKNIEAEYQALVQKEMERk....eeFRQEKETLEKEVQELKERQLGREELYAKLKE---.DSKIRWHRDKYKKLLKRFDEYYNKLEQKIADKEQQIVELTKLLE--vl..
D1AQ16_SEBTE/21-119 .............RTSTITKEAEKIEKAEEQRk....drLSRRKDKLESELAELLKNYNSRVEITEKLKM---.DSEVRWYRDEYKEILKKYESVQDNLEKEIEKKERELAIVNRGLG--is..
D0GMC3_9FUSO/33-131 .............SLNNLEKQLQRLDQMEQQK.......FNEQAALAQAAQQRLDKYLAMQATIDQRIADIEA.NADKSIFGKEFKQKMSEFKSLRSELDKEIKKEQKVLEDFELLKSLR....
C6JJE9_FUSVA/26-121 ............t-LDQLELNFQQLEAEEKAM.......YEKRKSEAEEAQRTLAQQRETYQQIVIQEKRIAD.VKNNRYYKDQYNQLAKKYADTKKALEEDMRRQEEIINLFEMI----k...
U2QXW1_9FUSO/35-133 .............SLSNLEAQLQKLEQMEENK.......FREQEAVANAAQQRLDNYLKMDAAIDQRIADIEA.NADTSIFGKEFKQKAAEYKKLKEELAKEIKKEQQILENFELLKSLR....
#=GC seq_cons .............phsslEsphpcLhppEppp.......appp+ttu-ststsLpppppscpplpp+lcph.t..s-scha+-pYppllccacslhppLsp.hcccppplspFpth.t......
//
