GenomeNet

Database: Pfam
Entry: Fanconi_A
LinkDB: Fanconi_A
Original site: Fanconi_A 
#=GF ID   Fanconi_A
#=GF AC   PF03511.10
#=GF DE   Fanconi anaemia group A protein
#=GF PI   Fanconia; 
#=GF AU   Griffiths-Jones SR
#=GF SE   PRINTS
#=GF GA   20.90 20.90;
#=GF TC   22.80 22.50;
#=GF NC   20.50 18.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   FANCA
#=GF DR   INTERPRO; IPR003516;
#=GF SQ   62
#=GS W5PYW1_SHEEP/1232-1293  AC W5PYW1.1
#=GS T0NGY9_9CETA/1093-1141  AC T0NGY9.1
#=GS U3D3N8_CALJA/1254-1316  AC U3D3N8.1
#=GS F1NLX0_CHICK/1231-1292  AC F1NLX0.2
#=GS H3BNS0_HUMAN/31-93      AC H3BNS0.1
#=GS E7FCS8_DANRE/1170-1229  AC E7FCS8.1
#=GS H3BT40_HUMAN/80-141     AC H3BT40.1
#=GS M3W0Z6_FELCA/1249-1315  AC M3W0Z6.1
#=GS G1N892_MELGA/1254-1315  AC G1N892.1
#=GS H9GDH7_ANOCA/227-283    AC H9GDH7.2
#=GS G1S183_NOMLE/310-372    AC G1S183.2
#=GS G1TF41_RABIT/1246-1308  AC G1TF41.1
#=GS W5M4W7_LEPOC/1211-1270  AC W5M4W7.1
#=GS H9Z6A8_MACMU/1254-1315  AC H9Z6A8.1
#=GS F7DU08_ORNAN/976-1038   AC F7DU08.1
#=GS I3MM43_SPETR/1249-1311  AC I3MM43.1
#=GS H3BSA3_HUMAN/1-33       AC H3BSA3.1
#=GS L8ITF6_9CETA/1255-1315  AC L8ITF6.1
#=GS H3AVM6_LATCH/1233-1295  AC H3AVM6.1
#=GS G3UTA2_MELGA/1229-1290  AC G3UTA2.1
#=GS G5APH5_HETGA/1320-1363  AC G5APH5.1
#=GS F6XRC0_HORSE/1227-1288  AC F6XRC0.1
#=GS Q4VT51_XENLA/1229-1289  AC Q4VT51.1
#=GS H2NRU7_PONAB/1229-1291  AC H2NRU7.1
#=GS G1PNC5_MYOLU/1258-1319  AC G1PNC5.1
#=GS U3JK75_FICAL/1094-1155  AC U3JK75.1
#=GS I3LKC7_PIG/1254-1315    AC I3LKC7.1
#=GS H3BS03_HUMAN/8-50       AC H3BS03.1
#=GS B7Z6Y4_HUMAN/231-292    AC B7Z6Y4.1
#=GS G3VVB8_SARHA/1255-1316  AC G3VVB8.1
#=GS S7MM77_MYOBR/986-1029   AC S7MM77.1
#=GS M3Y747_MUSPF/1026-1091  AC M3Y747.1
#=GS F7DCC2_MONDO/1226-1286  AC F7DCC2.1
#=GS H0ZCC5_TAEGU/950-1011   AC H0ZCC5.1
#=GS F7B4E5_XENTR/1155-1215  AC F7B4E5.1
#=GS FANCA_HUMAN/1254-1316   AC O15360.2
#=GS E1B6X8_BOVIN/1253-1314  AC E1B6X8.2
#=GS F6RNT6_CALJA/1228-1290  AC F6RNT6.1
#=GS G3S1E2_GORGO/1254-1316  AC G3S1E2.1
#=GS Q1X874_DANRE/1190-1249  AC Q1X874.1
#=GS F6XJF5_CALJA/501-563    AC F6XJF5.1
#=GS H2QBS1_PANTR/1191-1253  AC H2QBS1.1
#=GS G7NQA8_MACMU/1229-1290  AC G7NQA8.1
#=GS L5MEU4_MYODS/1205-1266  AC L5MEU4.1
#=GS D3ZQL0_RAT/991-1053     AC D3ZQL0.2
#=GS E2R4K5_CANFA/1251-1312  AC E2R4K5.2
#=GS B3Y9I3_CHICK/1229-1289  AC B3Y9I3.1
#=GS H0UYC2_CAVPO/1234-1296  AC H0UYC2.1
#=GS B2RWU3_MOUSE/1246-1308  AC B2RWU3.1
#=GS D2HVW1_AILME/1166-1231  AC D2HVW1.1
#=GS F6XRZ7_HORSE/1227-1288  AC F6XRZ7.1
#=GS H0WQV8_OTOGA/1249-1311  AC H0WQV8.1
#=GS G3VVB9_SARHA/1270-1332  AC G3VVB9.1
#=GS G3R5W6_GORGO/1195-1257  AC G3R5W6.1
#=GS FANCA_MOUSE/1246-1308   AC Q9JL70.2
#=GS R0JZ03_ANAPL/1233-1294  AC R0JZ03.1
#=GS G3GRQ3_CRIGR/1193-1255  AC G3GRQ3.1
#=GS L5JXE6_PTEAL/1010-1055  AC L5JXE6.1
#=GS G3TE82_LOXAF/1233-1295  AC G3TE82.1
#=GS K7FXF3_PELSI/230-250    AC K7FXF3.1
#=GS G1L3C5_AILME/1247-1312  AC G1L3C5.1
#=GS U3IFU6_ANAPL/1230-1291  AC U3IFU6.1
W5PYW1_SHEEP/1232-1293             .......EELFVSLFFFSLMGLLSSYLTPQ....-AIGSL.RALDICAEILGCLQKRRI.SWLLVFQLTEADVPVG......
T0NGY9_9CETA/1093-1141             lskldgq---------------------RE....EAADSR.RALDTCAEILGCLQRRRV.PWPRLFQLTEADAGLG......
U3D3N8_CALJA/1254-1316             .......EELLVFLFFFSLMGLLSSHLTPN....STLGPL.KALEVCAAVLECLEKRKI.SWLALFQLAESDTRLG......
F1NLX0_CHICK/1231-1292             ......l-QLLVSLLFFSLMDLISAKIAPK....EGVDFQ.TSLEWALEILQCLEERGI.SWPLLFLSAEEGS---rk....
H3BNS0_HUMAN/31-93                 .......EELLVFLFFFSLMGLLSSHLTSN....STTDLP.KAFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
E7FCS8_DANRE/1170-1229             ......t-QVLLYLFLYSIIELISAHLSQQ....ECVERV.RGV--CVCLLTRLQGH-S.DWLLLFDQCGSDHEL-c.....
H3BT40_HUMAN/80-141                .......EELLVFLFFFSLMGLLSSHLTSN....STTDLP.KAFHVCAAILECLEKRKI.SWLALFQLTESDA---ai....
M3W0Z6_FELCA/1249-1315             .......EELLVFLFFFSLMGLLSSHLTPHgrprQAVDTP.KALDICAEILGCLEKRRV.SWLVLFQLTETGGGLG......
G1N892_MELGA/1254-1315             .......EQFLVSLLFFSLMDLISAKIAPK....EGVDFQ.TSLEWALEILQCLEERGI.SWPLLFLSAEEGS---gk....
H9GDH7_ANOCA/227-283               .......EQLLVSLLFFSMMDVISARIALQ....EGVDAQ.KATDWSLAVLQRLNKQNI.SWLSVFTST-------g.....
G1S183_NOMLE/310-372               .......EELLVFLFFFSLMGLLSSHLTLN....STTDPP.KTFHVCAAILECLEKRKI.SWLALFQLTESDLSLG......
G1TF41_RABIT/1246-1308             .......EQLMVSLFFFSLMGLLSTRLTPN....GTADPR.KALHVCAEILLCLEQRGI.PWLGLFQLTEADAGLG......
W5M4W7_LEPOC/1211-1270             ......p-QLLVFLLFFSLMDLITAEIHPK....GPTDSQ.QAQERCADILKSLEDCG-.HWLVLFRGPSADQ---g.....
H9Z6A8_MACMU/1254-1315             .......EELLVFLFFFSLMGLLSSHLTSN....SATDPS.KALDVCAAVLECLEKRKI.SWLALFQLTESD-RLG......
F7DU08_ORNAN/976-1038              .......EQLLVSLFFFSLMGLISSHLAPQ....VRGDFP.KTLDMCSEILGCLERRRM.SWLIFFQSPKKGTGL-y.....
I3MM43_SPETR/1249-1311             .......EELLVPLFFFSLMDLLSSHLTPN....DTVDPP.KAVDTCAEVLECLQRRRV.DWLVLFQLTETDAGLG......
H3BSA3_HUMAN/1-33                  .......-----------------------....------.-AFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
L8ITF6_9CETA/1255-1315             ......r--LFVSLFFFSLMGLLSSYLTPQ....-AIGSL.RAVDICADILGCMQRRRI.SWLLVFQLTEADVPLG......
H3AVM6_LATCH/1233-1295             .......EQLL-SLFFFTLVDLISATLQPK....EKLESS.RKLEVCVEVIRTLEGKGVsSWLTLFLSGESEHSL-h.....
G3UTA2_MELGA/1229-1290             .......EQFLVSLLFFSLMDLISAKIAPK....EGVDFQ.TSLEWALEILQCLEERGI.SWPLLFLSAEEGS---gk....
G5APH5_HETGA/1320-1363             ..earpa-----------------------....-IADSL.KATEVCAEVLACLQRRKL.SWLGLFQLTEADAGLG......
F6XRC0_HORSE/1227-1288             ......h-RLLVCLFFFSLMGLLSSHLTPH....-IRDSL.KALHVCGEILGFLQKRKI.SWLVLFQLTETDAGLG......
Q4VT51_XENLA/1229-1289             .....mv---LISLLFFSVMDIIYMFL--K....DGRKHK.DLLENCVHIIHCLEQKGE.TWVWLFQMTDE-----rkpelg
H2NRU7_PONAB/1229-1291             .......EELLVFLFFFSLMGLLSSHLTSN....SATDPL.KAFHICAAILECLEKRKI.SWLALFQLTESDLMLG......
G1PNC5_MYOLU/1258-1319             .......EELLVVLFFFSLMGLLSTYLTPH....-AGSCL.TALDICAEILGCLEKRKV.PWLPLFRLTETDAGLG......
U3JK75_FICAL/1094-1155             .......EQLLVALLFFSLLDLISARIAPK....EGLDFQ.TSLEWSLEILQCLEERST.PWPLLFHSAERDP---gr....
I3LKC7_PIG/1254-1315               .......DELLLFLFFFSLMGLLASHVTPH....-AAGSP.EALAVCTEILGCLQRRRV.SWLPLFQLTEAGAGLG......
H3BS03_HUMAN/8-50                  .....re----------------------E....STTDLP.KAFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
B7Z6Y4_HUMAN/231-292               .......EELLVFLFFFSLMGLLSSHLTSN....STTDLP.KAFHVCAAILECLEKRKI.SWLALFQLTESGK---kh....
G3VVB8_SARHA/1255-1316             .......EELLVSLFFFSLMGLLSSYLAPN....ERMNSQ.KSLDICAEVLGCLEKRKL.SWLVLFQLTKKEN---as....
S7MM77_MYOBR/986-1029              ..tlywk-----------------------....-AGNCL.TALDICAEILGCLEKRKV.PWLPLFRLTETDAGLG......
M3Y747_MUSPF/1026-1091             .......EELLLALFFFSLMGLLSSHLTPHs.rhQAADSL.EALDICVEILGCLEKRKV.SWLVLFQLTGA-----aggpg.
F7DCC2_MONDO/1226-1286             .......EELLLPLFFFSLMSLLSSYLAPN....DGMSSL.KPLNICAEVLGCLEKRKI.SWLVLFQLTKKE----nv....
H0ZCC5_TAEGU/950-1011              .......EQLLVALLFFSLLDLISARIAPK....EGVDFQ.ASLEWSQQILQCLEGRGT.SWPHLFHSAEGDP---gk....
F7B4E5_XENTR/1155-1215             ......l-QVLISLLFFSVMDIIYMLL--K....DGKKHK.DLLDICVRIIHCLEEKGE.TWVWLFQITEPEFS--lh....
FANCA_HUMAN/1254-1316              .......EELLVFLFFFSLMGLLSSHLTSN....STTDLP.KAFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
E1B6X8_BOVIN/1253-1314             .......EELFVSLFFFSLMGLLSSYLTPQ....-AIGSL.RALDICADILGCLQRRRI.SWLLVFQLTEADVPLG......
F6RNT6_CALJA/1228-1290             .......EELLVFLFFFSLMGLLSSHLTPN....STLGPL.KALEVCAAVLECLEKRKI.PWLALFQLAESDTRLG......
G3S1E2_GORGO/1254-1316             .......EELLVFLFFFSLMGLLSSQLTSN....SATDPP.KAFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
Q1X874_DANRE/1190-1249             ......t-QVLLYLFLYSIIELISAHLSQQ....ECVERV.RGV--CVCLLTRLQGH-S.DWLLLFDQCGSDHEL-c.....
F6XJF5_CALJA/501-563               .......ERLLVFLFFFSLMGLLSSHLTPN....STLGPL.KALEVCAAVLECLEKRKI.PWLALFQLAESDTRLG......
H2QBS1_PANTR/1191-1253             .......EELLVFLFFFSLMGLLSSHLTSN....STRDLP.KAFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
G7NQA8_MACMU/1229-1290             .......EELLVFLFFFSLMGLLSSHLTSN....SATDPS.KALDVCAAVLECLEKRKI.SWLALFQLTESD-RLG......
L5MEU4_MYODS/1205-1266             .......EELLAVLFFFSLMGLLSTYLTPH....-AGNCL.TALDVCAEILGCLEKRKV.PWLPLFRLTETDAGLG......
D3ZQL0_RAT/991-1053                .......EELLITLLFFSLMGLLSSYLTQR....DTAEYQ.KAVDICAEVLACLERRKV.SWLMLFQLAETDAKLG......
E2R4K5_CANFA/1251-1312             .......EELLVVLFFFSLMGLLSSHLTPH....-AVDFL.KAVDICAEILRCLDKRKV.SWLVLFQLTDTDGGLG......
B3Y9I3_CHICK/1229-1289             .......EQLLVSLLFFSLMDLISAKIAPK....EGVDFQ.TSLEWALEILQCLEERGI.SWPLLFLSAEGG----sr....
H0UYC2_CAVPO/1234-1296             .......EELLAPFFFFSLLSLLSSHLIPS....AIADSL.MALEVCAEILACLERRKL.PWLGLFQLAETDAGLG......
B2RWU3_MOUSE/1246-1308             .......EELLIALFFFSLMGLLSSYLTQR....DTAEHL.KAVDICAEVLTCLERRKV.SWLVLFQLTEKDAKLG......
D2HVW1_AILME/1166-1231             ......k-QLLLVLFFFSLMGLLSSHLTPHs.rhQAVDSL.KALDICAEVLGCLEKRKI.PWLVLFQLTETEGGLG......
F6XRZ7_HORSE/1227-1288             ......l-QLLVCLFFFSLMGLLSSHLTPH....-IRDSL.KALHVCGEILGFLQKRKI.SWLVLFQLTETDAGLG......
H0WQV8_OTOGA/1249-1311             .......EELLVFLFFFSLMGLLSSHLSPN....DAGDSL.KALGVCAEVLECLEKRKI.SWVALFQLTETDAGLG......
G3VVB9_SARHA/1270-1332             .......EQLLVSLFFFSLMGLLSSYLAPN....AVAQLPsTHRNICAEVLGCLEKRKL.SWLVLFQLTKKEN---as....
G3R5W6_GORGO/1195-1257             .......EELLVFLFFFSLMGLLSSQLTSN....SATDPP.KAFHVCAAILECLEKRKI.SWLALFQLTESDLRLG......
FANCA_MOUSE/1246-1308              .......EELLIALFFFSLMGLLSSYLTQR....DTAEHL.KAVDICAEVLTCLERRKV.SWLVLFQLTEKDAKLG......
R0JZ03_ANAPL/1233-1294             ......l-QLLVSLLFFSLMDLISAKIAPK....EGVDFQ.TSLEWSLEILQCLEERGA.SWPLLFQSAEKGS---rk....
G3GRQ3_CRIGR/1193-1255             ......k-ELLISLLFFSLMSLLSSYLTQQ....DTAEYL.KAMDICAEVLECLERRKV.SWLMLFQLTETDAELG......
L5JXE6_PTEAL/1010-1055             .....lv-------------------LTSA....LAVDFL.KAVGVCAEILGCLQERNV.PWLQLFQLTKTEAH--eg....
G3TE82_LOXAF/1233-1295             ......d-KVLLFLLFFSVMGLVSAYLAPS....ETIDPP.KMLDVCAEILKCLERRRV.PWLALFQLTEMGAG--pg....
K7FXF3_PELSI/230-250               .......EQLLVCLLFFSLMDFISTRF---....------.------------------.----------------a.....
G1L3C5_AILME/1247-1312             .......EELLLVLFFFSLMGLLSSHLTPHs.rhQAVDSL.KALDICAEVLGCLEKRKI.PWLVLFQLTETEGGLG......
U3IFU6_ANAPL/1230-1291             .......EQLLVSLLFFSLMDLISAKIAPK....EGVDFQ.TSLEWSLEILQCLEERGA.SWPLLFQSAEKGS---rk....
#=GC seq_cons                      .......EpLLV.LFFFSLMuLLSoaLssp....pssD...+Al-lCA-ILpCLE+R+l.SWLsLFQLTEsDstL.......
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