#=GF ID   Sigma_1s
#=GF AC   PF02454.20
#=GF DE   Sigma 1s protein
#=GF AU   Mian N;0000-0003-4284-4749
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_2133 (release 5.4)
#=GF GA   21.00 21.00;
#=GF TC   21.00 22.10;
#=GF NC   20.70 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2398530
#=GF RT   Sequence diversity in S1 genes and S1 translation products of 11
#=GF RT   serotype 3 reovirus strains. 
#=GF RA   Dermody TS, Nibert ML, Bassel-Duby R, Fields BN; 
#=GF RL   J Virol 1990;64:4842-4850.
#=GF DR   INTERPRO; IPR003478;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The reoviral gene S1 encodes for haemagglutinin (sigma 1
#=GF CC   protein), an outer capsid protein and a major factor in
#=GF CC   determining virus-host cell interactions. Sigma 1s is one of two
#=GF CC   translation products of the S1 gene.
#=GF SQ   4
#=GS A0A430JSZ6_9ACTO/1-81       AC A0A430JSZ6.1
#=GS SIG1S_REOVJ/3-125           AC P32868.1
#=GS SIG1S_REOVL/1-115           AC P07938.1
#=GS A0A1Y2E5M1_9FUNG/2339-2432  AC A0A1Y2E5M1.1
A0A430JSZ6_9ACTO/1-81                  ....ma-------SSKKIRKARKRTLITSLSSAR..SFIQPMTTASRYAPIRIPAHNHASSARCESSAWRNRSNKYGTAPMAAVA---------------------------...-------....-----krpatatva..
SIG1S_REOVJ/3-125                      ......NQPTRNTRSRKLRNKLKTSLLMSTGSVT..SLIQSKDNWVDYLYACQPLNRELVRTAIELIDSSEMSPAYRLALAESIRVYPSWVTESMLQNSELASWIQSRIISLsehQDWKLKYqpllMTLDH...........
SIG1S_REOVL/1-115                      ......MAPS-QKKSRKSRNKSRSTLMISGLPIL..NSTDLEDRLLTSAIASQPLSQDWVRWIIDLWVSRVRSRNYLTQVARTLRAYPHWVTESMLSNHELTVWIRSRLISL...DEHPLWR....QMLEA...........
A0A1Y2E5M1_9FUNG/2339-2432             nginnn---------KSSVNKSNEILIVSNSSINkeNSTDDDEENTTITLVKIPFNDDLLDTIIKSKKYKVIETNQKNINMDIINDTPNLVT--------------------...-------....-----pnskdiayann
#=GC seq_cons                          .............pS+K.RNKp+poLlhSsuSlp..s.hpsc-phsshshsp.Phsp-hlcshI-.hs.+shSssYtstshcslpshPphVT..................................................
//