GenomeNet

Database: Pfam
Entry: AHH
LinkDB: AHH
Original site: AHH 
#=GF ID   AHH
#=GF AC   PF14412.3
#=GF DE   A nuclease family of the HNH/ENDO VII superfamily with conserved AHH
#=GF AU   Zhang D, Iyer LM, Aravind L
#=GF SE   Manual
#=GF GA   19.70 19.70;
#=GF TC   20.30 20.80;
#=GF NC   19.30 19.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21306995
#=GF RT   A novel immunity system for bacterial nucleic acid degrading
#=GF RT   toxins and its recruitment in various eukaryotic and DNA viral
#=GF RT   systems.
#=GF RA   Zhang D, Iyer LM, Aravind L;
#=GF RL   Nucleic Acids Res. 2011;39:4532-4552.
#=GF CC   AHH is a predicted nuclease of the HNH/ENDO VII superfamily of
#=GF CC   the  treble clef fold. The name is derived from the conserved
#=GF CC   motif, AHH. It is found in bacterial polymorphic toxin systems
#=GF CC   [1] and functions as a toxin module. Like WHH and LHH, the AHH
#=GF CC   nuclease contains 4  conserved histidines of which, the first
#=GF CC   one is predicted to bind       a metal-ion and the other three
#=GF CC   ones are involved in activation of a water molecule for
#=GF CC   hydrolysis.
#=GF SQ   137
#=GS Q2SED4_HAHCH/115-253        AC Q2SED4.1
#=GS F8K562_STREN/1169-1281      AC F8K562.1
#=GS F2LC89_BURGS/1357-1458      AC F2LC89.1
#=GS A9GHJ5_SORC5/57-195         AC A9GHJ5.1
#=GS D0LHG4_HALO1/677-805        AC D0LHG4.1
#=GS H8GI20_METAL/714-807        AC H8GI20.1
#=GS Q1D2W8_MYXXD/319-423        AC Q1D2W8.1
#=GS A0A075JR63_9BACI/44-144     AC A0A075JR63.1
#=GS W0RQJ2_9BACT/80-220         AC W0RQJ2.1
#=GS Q1DG90_MYXXD/123-249        AC Q1DG90.1
#=GS R6P0M7_9FIRM/227-322        AC R6P0M7.1
#=GS B7VTP8_VIBTL/42-190         AC B7VTP8.1
#=GS D0LLJ7_HALO1/619-744        AC D0LLJ7.1
#=GS D5DHF2_BACMD/139-242        AC D5DHF2.1
#=GS C5BJW5_TERTT/97-249         AC C5BJW5.1
#=GS D3V9F6_XENNA/2-107          AC D3V9F6.1
#=GS F9YPK9_CAPCC/1536-1646      AC F9YPK9.1
#=GS S5YEV2_PARAH/1461-1569      AC S5YEV2.1
#=GS E3FCQ3_STIAD/1-59           AC E3FCQ3.1
#=GS B2FKS6_STRMK/1-107          AC B2FKS6.1
#=GS Q1CVL5_MYXXD/372-477        AC Q1CVL5.1
#=GS H8MK17_CORCM/321-424        AC H8MK17.1
#=GS A7MQ44_CROS8/1219-1331      AC A7MQ44.1
#=GS Q1DG21_MYXXD/327-432        AC Q1DG21.1
#=GS F2LTA6_BURGS/1292-1403      AC F2LTA6.1
#=GS U4K8W4_9VIBR/110-224        AC U4K8W4.1
#=GS Q08QB8_STIAD/311-416        AC Q08QB8.1
#=GS Q82R58_STRAW/2256-2358      AC Q82R58.1
#=GS D0LJ11_HALO1/688-815        AC D0LJ11.1
#=GS B7VTQ8_VIBTL/39-194         AC B7VTQ8.1
#=GS F2LSX3_BURGS/1434-1539      AC F2LSX3.1
#=GS H8MY96_CORCM/331-438        AC H8MY96.1
#=GS H8MYF8_CORCM/325-428        AC H8MYF8.1
#=GS Q8XQT2_RALSO/1407-1507      AC Q8XQT2.1
#=GS D3V4E6_XENBS/1-69           AC D3V4E6.1
#=GS H8MYF6_CORCM/325-428        AC H8MYF6.1
#=GS Q1DCW1_MYXXD/336-441        AC Q1DCW1.1
#=GS E8JZM3_9STRE/1-63           AC E8JZM3.1
#=GS G8ULB3_TANFA/1-102          AC G8ULB3.1
#=GS A1KCD9_AZOSB/91-260         AC A1KCD9.1
#=GS F9TDW9_9VIBR/12-135         AC F9TDW9.1
#=GS C2X4L3_BACCE/417-525        AC C2X4L3.1
#=GS F2RLW5_STRVP/1045-1153      AC F2RLW5.1
#=GS Q87PT6_VIBPA/544-679        AC Q87PT6.1
#=GS H8MES6_CORCM/251-358        AC H8MES6.1
#=GS B7VTR2_VIBTL/40-124         AC B7VTR2.1
#=GS A0A0C3MA84_9PORP/302-400    AC A0A0C3MA84.1
#=GS A0A068QSM2_9ENTR/1336-1437  AC A0A068QSM2.1
#=GS R7JZ69_9CLOT/252-388        AC R7JZ69.1
#=GS Q1D4C5_MYXXD/316-423        AC Q1D4C5.1
#=GS G8M292_CLOCD/622-718        AC G8M292.1
#=GS R5PUS9_9BACT/1-72           AC R5PUS9.1
#=GS G2PQ73_MURRD/571-665        AC G2PQ73.1
#=GS D0LIF3_HALO1/558-682        AC D0LIF3.1
#=GS A0A075MLA3_9RICK/2846-2946  AC A0A075MLA3.1
#=GS M5E2E1_9GAMM/81-186         AC M5E2E1.1
#=GS Q08Y34_STIAD/330-436        AC Q08Y34.1
#=GS M5DVU1_9GAMM/114-223        AC M5DVU1.1
#=GS B7VTS0_VIBTL/57-171         AC B7VTS0.1
#=GS F9TDX3_9VIBR/1-116          AC F9TDX3.1
#=GS Q81H88_BACCR/21-129         AC Q81H88.1
#=GS D3VAU8_XENNA/42-143         AC D3VAU8.1
#=GS Q1DCQ9_MYXXD/116-240        AC Q1DCQ9.1
#=GS B7VU40_VIBTL/30-162         AC B7VU40.1
#=GS B7VTR6_VIBTL/40-151         AC B7VTR6.1
#=GS Q1DF18_MYXXD/329-436        AC Q1DF18.1
#=GS A0A090IH35_9GAMM/550-678    AC A0A090IH35.1
#=GS D0LKQ6_HALO1/813-930        AC D0LKQ6.1
#=GS U9T9F5_RHIID/21-128         AC U9T9F5.1
#=GS K4IYI2_PSYTT/708-822        AC K4IYI2.1
#=GS A0A090IHZ4_9GAMM/42-167     AC A0A090IHZ4.1
#=GS Q093Y1_STIAD/327-433        AC Q093Y1.1
#=GS H8MWR1_CORCM/322-427        AC H8MWR1.1
#=GS G8Q7B0_PSEFL/2958-3065      AC G8Q7B0.1
#=GS F9YW06_CAPCC/8-126          AC F9YW06.1
#=GS R5JAS2_9BACE/948-1054       AC R5JAS2.1
#=GS S5ZZY3_9SPIO/384-498        AC S5ZZY3.1
#=GS A0A023Y7W8_9GAMM/1444-1555  AC A0A023Y7W8.1
#=GS U5MQZ0_CLOSA/41-152         AC U5MQZ0.1
#=GS A0A090IEA7_9GAMM/34-155     AC A0A090IEA7.1
#=GS G8ULB1_TANFA/486-592        AC G8ULB1.1
#=GS M5DSZ4_9GAMM/72-180         AC M5DSZ4.1
#=GS Q1DCY3_MYXXD/320-423        AC Q1DCY3.1
#=GS D3F4T5_CONWI/1777-1905      AC D3F4T5.1
#=GS Q97M65_CLOAB/622-727        AC Q97M65.1
#=GS Q2SAG3_HAHCH/73-226         AC Q2SAG3.1
#=GS Q2G616_NOVAD/5-122          AC Q2G616.1
#=GS B0X8Y0_CULQU/1642-1751      AC B0X8Y0.1
#=GS E3FR61_STIAD/329-436        AC E3FR61.1
#=GS A7MQ50_CROS8/1401-1508      AC A7MQ50.1
#=GS A1TJK5_ACIAC/3-103          AC A1TJK5.1
#=GS Q1DG56_MYXXD/153-287        AC Q1DG56.1
#=GS Q2SPA9_HAHCH/26-132         AC Q2SPA9.1
#=GS E3FLQ2_STIAD/25-135         AC E3FLQ2.1
#=GS H8MRJ0_CORCM/290-393        AC H8MRJ0.1
#=GS C5BUJ2_TERTT/115-225        AC C5BUJ2.1
#=GS H8MYF1_CORCM/267-370        AC H8MYF1.1
#=GS B7VTP2_VIBTL/9-135          AC B7VTP2.1
#=GS K9VSJ6_9CYAN/116-228        AC K9VSJ6.1
#=GS I0DRL7_PROSM/92-198         AC I0DRL7.1
#=GS A0A097QLK6_9VIBR/19-131     AC A0A097QLK6.1
#=GS Q9KAE6_BACHD/142-247        AC Q9KAE6.1
#=GS Q2S6Q8_HAHCH/144-267        AC Q2S6Q8.1
#=GS F9YVS2_CAPCC/181-290        AC F9YVS2.1
#=GS A0A0B5EV03_9ACTN/1434-1544  AC A0A0B5EV03.1
#=GS Q1DAJ7_MYXXD/86-211         AC Q1DAJ7.1
#=GS E3FUQ4_STIAD/250-333        AC E3FUQ4.1
#=GS Q6CZ60_PECAS/11-112         AC Q6CZ60.1
#=GS H8GU39_DEIGI/821-937        AC H8GU39.1
#=GS Q16LV5_AEDAE/1611-1719      AC Q16LV5.1
#=GS B7VTQ4_VIBTL/18-146         AC B7VTQ4.1
#=GS H8MXW0_CORCM/310-417        AC H8MXW0.1
#=GS D0LZ57_HALO1/238-363        AC D0LZ57.1
#=GS Q6LMQ8_PHOPR/26-149         AC Q6LMQ8.1
#=GS D0LTA7_HALO1/753-880        AC D0LTA7.1
#=GS K4KH34_SIMAS/77-181         AC K4KH34.2
#=GS Q1D471_MYXXD/90-212         AC Q1D471.1
#=GS Q1DE13_MYXXD/325-431        AC Q1DE13.1
#=GS F2NX86_TRES6/286-404        AC F2NX86.1
#=GS D8MMS3_ERWBE/1397-1498      AC D8MMS3.1
#=GS U5MMI8_CLOSA/91-206         AC U5MMI8.1
#=GS A7GLS5_BACCN/1-104          AC A7GLS5.1
#=GS D3VA39_XENNA/1335-1436      AC D3VA39.1
#=GS F2NX75_TRES6/163-287        AC F2NX75.1
#=GS R7CZP8_9BACE/743-860        AC R7CZP8.1
#=GS R6CII2_9BACE/1-58           AC R6CII2.1
#=GS N8YFR2_9GAMM/29-131         AC N8YFR2.1
#=GS Q97IJ7_CLOAB/201-306        AC Q97IJ7.1
#=GS H8MHW8_CORCM/326-427        AC H8MHW8.1
#=GS Q1CWH6_MYXXD/114-220        AC Q1CWH6.1
#=GS A0A0A7PGU8_9SPHN/3-117      AC A0A0A7PGU8.1
#=GS D0LNH0_HALO1/697-823        AC D0LNH0.1
#=GS R7RAP8_9FIRM/94-203         AC R7RAP8.1
#=GS I0DWQ7_PROSM/1442-1548      AC I0DWQ7.1
#=GS E3FGA3_STIAD/311-416        AC E3FGA3.1
#=GS U4K522_9VIBR/110-232        AC U4K522.1
#=GS F9YW08_CAPCC/2-107          AC F9YW08.1
Q2SED4_HAHCH/115-253                   ..........tl--VEVNNFTTGFAPYGNQVHHIVNISSVRNGIEEIAKdlpdlr......vlivnglLDEKYNIN.....YK--.DNSLIL............P.......................................................TQRSASAKTGLPSHYGS..............H..................................-PSYSKDIlq..........hvKQALQPYKKIANEM..KKNK..P..HSKPDpvelkkkL-------edaskklykei...................................................................
F8K562_STREN/1169-1281                 ..........rl--RKNMAREGRVVGPGQAAAHIVPSNGRNFRQWRWGKks...............sdLLDRYGID.....INDP.ANGIPL............-.......................................................------------GHPKP..............Hnf..............................thRGPFLQRL..............NARLVRVVEQGQAD..GLGA..R..AIRTRlr...qeLRSIGRQI..............................................................................
F2LC89_BURGS/1357-1458                 ...........n-MMEDMGLPRSTGWKGYQAHHVIPKELYNHP------...................ALERINYD.....IDSA.DNGIFL............-.......................................................-RKTDDGVSTMSRHQGN..............H..................................-DGYTQSV..............KDALDKIDLNQSNS..EIAK..Q..V--AD.......IQNVAK--k.............................................................................
A9GHJ5_SORC5/57-195                    .......ekqsi-----YHNNSFPPSYAYQGHHCIALKTLVQDANSSPKdril...........rlnhFLKKVGFY.....PNRD.KNCIGL............Pemaskk...........................................rqdyenFWLSIDEGKPLQLHGPG..............H..................................DHRYFNAC..............TAMMQRLLELIVP-..----..-..-----.......--------daedcektsksdwendlkeliaqa......................................................
D0LHG4_HALO1/677-805                   .........vge---LLARAGHTARPPYHQAHHVIPDEVVRKSNLMRL-...................ARQRGVFD.....PDAI.ENIALL............Akrevre..........................................egkapftPAKVPGLSAPLPRHQGP..............H..................................-PAYSEVI..............LQAARRAEQELLEQ..GFTS..L..DEVPDe.....lLK------vatkdiqr......................................................................
H8GI20_METAL/714-807                   ......ltknia------DARQEVKQKGESAHHIVAAGDFRAEGSRQ--...................ILENAGMD.....INDA.NNGLLM............-.......................................................---------HTMYHERI..............H..................................TNEYYRAV..............DESLRGASTYNEVA..SR--..-..-----.......LSNIRAE-i.............................................................................
Q1D2W8_MYXXD/319-423                   ....avgavrgi-----------QGDPEGEIHHICTNKNDKSDRTGGPWtpr.............freIFDKAGMS.....LNDP.ANLIRI............-.......................................................-----------KGHQGS..............H..................................PREYHEIV..............HGRLLEVVQGCRGV..AMCR..R..ALERE.......LAAIAREL..............................................................................
A0A075JR63_9BACI/44-144                ...rgligdppi------------AMIDPHAHHILFKKGLGEAQQKLVQeg...............qeILRKYDID....pVIGK.ENLVWA............P.......................................................-----------NRVAGQ..............H..................................SIAALKNV..............VNQLKAVDAA----..----..-..-----.......--------gadlddiieiledlgkqv............................................................
W0RQJ2_9BACT/80-220                    .qenvfeeievh--------------IPPAAHHLIPGDAVMAKTQIEQWtce............skgkIKEDIGYN.....IDGA.PNGIWL............Phlphihwtrfmnkatktr...................fsdvfgtwsslsdyrrkaVGYVIMSETWLQMHYTD..............H..................................-KGSYKYV..............DD------------..----..-..-----.......--------denynneaktrcnllanv............................................................
Q1DG90_MYXXD/123-249                   ........akdk----DKKPALQKYPYAWEAHHILPGSAFYYELEDGPVfty............rqlrLILQSDYN.....LNHG.HNIIML............P.......................................................DQAWAVPVHALLQHPGD..............H..................................-PNYTQQV..............MRDMKTIAQKLQKA..IDSQ..K..EHKAL.......IEDVFD--qlhklenky.....................................................................
R6P0M7_9FIRM/227-322                   .......qlgnv------GESGTPSTKPNQIHHFATNKSKKYTSQFEN-...................IAKKYGLD.....LDGD.WNKELM............P.......................................................-------------HQGR..............H..................................PYAYHEYV..............LDNMQKFDKIAKGD..KTKF..-..-----.......--------lmlydqmkqki...................................................................
B7VTP8_VIBTL/42-190                    ......ydskcn-----------TEKGGLQAHHIVTTESLDGHLWKL--...................WREAYEYD.....INRA.NNGVML............P.......................................................SSTIIACQVETHVHRSN..............HnrgldydtvldkywggkakpeeipdeeceklyseLRTYLKGV..............NKQIGEIKKRAEKK..YYCK..S..SNKKEft...edLDDA----aedivdkl......................................................................
D0LLJ7_HALO1/619-744                   .........vge---LLARAGHTARPPYHQAHHVIPNEVVRSHLLFRL-...................ARERGVFD.....HDAP.ENIALL............Arsevre..........................................pgrapfvPEKIPGLSEGLPRHQGP..............H..................................-RRYTRAV..............IDAARSTELEVLTM..GYR-..-..-----.......--------ivdlddatlklladrv..............................................................
D5DHF2_BACMD/139-242                   ........nlle----SMGLPRSKSWKGYQAQHIIPSQLNKHP------...................VIKKIGME.....MNDS.TNGIFL............P.......................................................--IPSDDVSSLSRHRGF..............H..................................-SVYNNVV..............RKQLDKMDVNQDIA..VLEK..Q..VY--E.......LQ------qklkkgv.......................................................................
C5BJW5_TERTT/97-249                    .......vplkv---------------STAAHHLIPGNASLKNSDIMEFlht.............dgmAKGNIGYN.....VNNY.ENGVWL............Agnyalrgkggmpkwg........................kegktfrsdtklepyeYAKRAIEKTQTQFHDA-..............H..................................-KSYSDTL..............LKALDLIAEKYETT..QD--..-..-----.......--------vwcteasapksdskpqlpmlvmrlntisrr................................................
D3V9F6_XENNA/2-107                     ......agrkyd---------------RLSAHHVIPVEIRKENQK----...................FLDKIGIGg...rMNSV.ENGIHI............Pgs...................................................kkAMQDDVGKGMKVFHSSN..............H..................................-NTYSGEV..............REAIDVIKEDYRNK..KIND..R..QARDE.......IRKLQM--km............................................................................
F9YPK9_CAPCC/1536-1646                 ...nvfmkydlg------------EPLNFEVHHIIPINILKENEKLQQLll...............waEQNGKKFD.....FNGL.DNGIPL............-.......................................................--QKKRLKYGVNGHAK-..............H..................................-PNYDEAI..............IPKIENITSSNVLK..NEEK..L..EVIQD......iVNKAKE--kl............................................................................
S5YEV2_PARAH/1461-1569                 ..........nl--MDDMGMPRGTRAPGYQAQHVIPGALDNHP------...................AWRMGGQD.....IDGA.GNGMFL............Pdr..................................................ganSASNADRVSPLTRHQGS..............H..................................-KGYNDAV..............EAAMNRIDLSLGPQ..HVAS..E..--IQR.......LQNV----lrq...........................................................................
E3FCQ3_STIAD/1-59                      ............-------------------------------------...................------MS.....LNDP.ANKVRV............-.......................................................-----------QGHQGP..............H..................................PQEYRERI..............YNRLDEATKGCSSI..EQCR..K..ALTAE.......LERLAKQI..............................................................................
B2FKS6_STRMK/1-107                     .........mad-------------TPVFQGHHLIEQNAFEQSQLLKS-...................LARSGHFT.....LHGS.DNILNL............P.......................................................ANPALATRLGISPHSGG..............P..................................LSAYSDQL..............KFVLDDLAETYDGR..ALLA..K..DSAPD.......VRA-----aaaermaar.....................................................................
Q1CVL5_MYXXD/372-477                   .........ava-----MAAGGSSGAGRIQKHHIATNKNDVSAARGGPWtpe.............frrIFKRAGME.....LKDP.ENIVQI............-.......................................................-----------QGHQGP..............H..................................PQAYHELV..............FRRLNSATARCRSV..EECR..K..VLTKA.......LQQLARE-a.............................................................................
H8MK17_CORCM/321-424                   gavatggpvevp----------------GPKHHIASDKFSTSTANGGPWtpr.............yeeIFERAGMS.....LNDP.ENQVHV............-.......................................................-----------PGHQGP..............H..................................PREYHVRV..............YNELNLATSNCTTL..AQCR..D..SLTRM.......LRSLAKEL..............................................................................
A7MQ44_CROS8/1219-1331                 .......akala-----NGHVIPAGMTNPHGHHIVFKGQYQGTSLAPHLsr..............skaILKRYGID....pVNDP.ANLMIA............-.......................................................-----------NNGEGV..............H..................................TEKNAKKV..............ADALVKADKEIKEI..SKCK..K..LTGSDrt...nlL-------kqklqeig......................................................................
Q1DG21_MYXXD/327-432                   .navamaaqgms-------------GGRSENHHLATNKNGVSTVRGGPWtpr.............fkrIFKKAGME.....LEDP.ENIVPV............-.......................................................-----------KGHKGP..............H..................................PQRYHERV..............YARLEEATKGCRKM..TECR..E..ALVNE.......LRQLAKE-a.............................................................................
F2LTA6_BURGS/1292-1403                 ..........kl--SNNMEKSGVTRPANSAAHHIVGDTSKEAAPARA--...................ILAKYGID.....VDSE.LNGVFL............P.......................................................-NRNNSDDLAGILHNGK..............H..................................PNTYFQKV..............NQLIQNADLGGKQA..VLDQ..L..QTIRE......tLQNASR--dm............................................................................
U4K8W4_9VIBR/110-224                   ....lvsnlyai--------AEPKPSPNHAAHHIVMGNGQVRAMINARL...................QMFMYGIG.....INDS.INGIWL............Pr....................................................stAYKGHYTTPKAPIHSRI..............H..................................GHNYQRWV..............GK-LADIRNNES--..----..-..-----.......--------afrarlvniktqlkdgshp...........................................................
Q08QB8_STIAD/311-416                   .....avamysn---------DIRGDSEGPVHHICTNKNLASAASGGPWtpq.............cekIFKKAGMS.....LEDA.ANKVRL............-.......................................................-----------NGHEGP..............H..................................PERYHKEV..............VDRLERAVERCRTT..ETCR..I..KLMRE.......LANISDEL..............................................................................
Q82R58_STRAW/2256-2358                 ..........lg---DNMTAAGTIRPAETAAHHIVASASPKAASARA--...................KLASVGID.....INDA.DNGVFL............P.......................................................RGSASPNLTGASVHSRI..............H..................................TNNYYGYV..............NDMMSGVRTANEAR..DV--..-..-----.......LNHIRNQL..............................................................................
D0LJ11_HALO1/688-815                   .........vge---LLTRAGHTARPPHHQAHHVIPDEVVRTHPLFRL-...................ARERGVFD.....HDAP.ENIALL............Arsevre..........................................pgrapfvPEKIPGLSEGLPRHQGP..............H..................................-GDYTRMI..............RRLVDEAGESLHAR..GLRL..D..AVSDE......vLERL----idklts........................................................................
B7VTQ8_VIBTL/39-194                    ...adgrlkgdd------------GQFGLQAHHIITTKNLDTPDWKK--...................YREAYEYD.....INTW.KNGVMF............P.......................................................SKTDIACQVNTHVHKSG..............Hgggl..........................dfktE-------..............--------------..----..-..-----.......--------qeqfwetssdpesgevtsipvtkvpdpvvtklrledikyiksvnrdikgvkenaqrkyycktgntryfqsdldgvsed
F2LSX3_BURGS/1434-1539                 ........alaa----AMNDTGIPTPVDSAAHHIVGETSAGAQPARD--...................ILAQHGIG.....IDSA.HNGVFL............P.......................................................-NKNNTDDMPGICHCGR..............H..................................PNAYLDAV..............NRRLQRASEQDGKQ..GVLS..E..-----.......--------ldnmrgtl......................................................................
H8MY96_CORCM/331-438                   .......sardd-----KGPVATGVDAKGQEHHIASNKFWNATNRGGPWspe.............fqkIFDKAGMS.....LDDA.ANKVSV............-.......................................................-----------PGHRGP..............H..................................PEAYHRRV..............FTALRDATATCRTM..QDCR..A..SLTRA.......LQRLASQI..............................................................................
H8MYF8_CORCM/325-428                   ......pnavam----------SSRSGKPQRHHLATIRNEKSSKTGGPWtpl.............frrIFKRAGME.....LKDP.ENIIEV............-.......................................................-----------PGHRGP..............H..................................PRAYHERI..............YNRLDEATQGCRSV..EACR..E..ALTQE.......LRALANE-a.............................................................................
Q8XQT2_RALSO/1407-1507                 .........dlv---RKYEGDPPADMTNPHGHHAVFKKGRGTKMREYLDes...............kdILENYDID.....WYKGrENLGWA............P.......................................................--------------NKN..............H..................................STAAAKAV..............RDALKDAHENIGTK..EAVV..E..A----.......LSKIKK--hf............................................................................
D3V4E6_XENBS/1-69                      ...........m-------------------------------------...................--------.....----.ENGIHI............Pgs...................................................kkAMQDDVGKGMKVFHSSN..............H..................................-NTYSGEV..............RQSIEEIKRRHDAG..NLSD..R..QARDE.......IRKLQM--km............................................................................
H8MYF6_CORCM/325-428                   ......pnavam----------SSRSGKPQRHHLATIRNEKSSKTGGPWtpl.............frrIFKRAGME.....LKDP.ENIVEV............-.......................................................-----------PGHRGP..............H..................................PAEYHQLV..............YDRLRQVTSDCRSV..EACR..E..ALTDA.......LRILGEQ-a.............................................................................
Q1DCW1_MYXXD/336-441                   ..tavamstqds------------SKRWTHRHHLATNKNSVSTARGGPWtpr.............feeFFKKAGME.....LKDP.ENIVPV............-.......................................................-----------QGHHGP..............H..................................PQEYHALV..............FARLRDATRACRTV..ESCR..K..ALTSA.......LSEMAEE-v.............................................................................
E8JZM3_9STRE/1-63                      ...........m-------------------------------------...................--------.....----.-----L............P.......................................................--EVKSKGTTRAKHLGY..............H..................................-KAYSDAI..............AQLIDDIDQSSKCD..KEKA..R..K----.......IQSL----qarahkalkkgkl.................................................................
G8ULB3_TANFA/1-102                     .........mar---------RWKKFKGSAAHHIVAGDHMDPNAIKARS...................ILSKHGID.....IDDA.ANGIYL............-.......................................................KHMDPNSIQPGAYHRVI..............H..................................TKIYFENV..............ANRLEIADLIGGKN..GVLD..E..-----.......LDN-----iagdl.........................................................................
A1KCD9_AZOSB/91-260                    ...aatgkdyeh-----------RYPVTCAAHHLVPAQEALKQSHLLAFmvkkgetaklkdkdfskgvVWANVGYE.....VNGA.ENGIYL............PgsyavgggrgglklwvenddmpdkeeedvteeadpaspqlygrlneisaanrkwqYVRQAVAKAPGQFHDR-..............H..................................-VDYSNFV..............TSVL----------..----..-..-----.......--------dkifedyrrryfks................................................................
F9TDW9_9VIBR/12-135                    .......pakld------PSHPTNHGFQMQVHHLLSKQGVKKTGNGD--...................KLKSYGYD.....INLP.GNLVAL............P.......................................................CTLEGACHLQVQLHRGN..............Hptvidt.....................ndndkehPKGYHIEVte..........lvEEAYKTISKRCENQ..----..-..-----.......--------gnpgvqrymdyhsl................................................................
C2X4L3_BACCE/417-525                   ..........lr--EELKAAGIEPPPYSNAAHHLTPWNDKRAVEAQE--...................LLKEFGIH.....HDSA.ANGVFL............P.......................................................-YKVNEYVTTEVLHIGN..............H..................................GTDYMKEV..............TKVLKEVKEYGGTQ..ADAV..A..AL---.......-HD-----lrtrlld.......................................................................
F2RLW5_STRVP/1045-1153                 ........mtqs-----MEKIGQYKSHGQAAHHGVPASDRKAQPARD--...................ILEWAGVN.....PDDCpLNGIYL............Tq.....................................................tSRDSKVIHEAGTLHEVL..............H..................................TDNYYKAI..............TERLVEARKFGGAD..G---..-..-----.......--------vihemsrikedl..................................................................
Q87PT6_VIBPA/544-679                   ..........gw--RDKTEHPWWHGAGAVQAHHLIPKNAFKLKNAKSKQtkekm.........mflrrIAQTCAYN.....IDFW.KNGIGL............P.......................................................NKKETACFLRKPRHAGG..............Hdrn...........................efnyTNECVKLV..............HDKLSSDIKKRTKE..GSCS..K..TTNSS.......--------limkfnessknif.................................................................
H8MES6_CORCM/251-358                   ........aala----MYSDNRIPGDAEGPVHHICTNKNRVSAVSGGPWtpa.............ceeIFEKAGMT.....LEDA.ANKVRL............-.......................................................-----------KGHEGP..............H..................................PELYHNQV..............VNRLQASVRTCRTT..EACR..A..KLLNE.......LAKIASEL..............................................................................
B7VTR2_VIBTL/40-124                    .....gdsrvns------------DQCGLEAHHIITTKNLGTPDWKK--...................YRKAYEYD.....INSW.ENGVML............P.......................................................SEPDIACQAFTHVHRSH..............H..................................N-------..............--------------..----..-..-----.......--------ggldftsvktkywkege.............................................................
A0A0C3MA84_9PORP/302-400               ........plgk-----SNSIRKASKLPTQIHHFATNKNKMFTPQMKK-...................IAEQFGLD.....LNGD.WNKAVL............P.......................................................-------------HLGR..............H..................................PNDYHKFV..............LQNMEKARLEANGN..QVKF..-..-----.......--------lqlfdqyvkapllq................................................................
A0A068QSM2_9ENTR/1336-1437             ...........n-MMEDMGLSRSTKWSGYQAHHVIPKELANHP------...................ALKKINYD.....IDVA.ANGIFL............-.......................................................-RKADNGVSAMARHQGN..............H..................................-HGYTDAV..............RNALDRIDLQQSKE..AISK..Q..VAN--.......IQDIAK--k.............................................................................
R7JZ69_9CLOT/252-388                   ...........a-EEKEELEIKRYDLAAVAAHHMVPVKDMLRKQSGERYssid...........fwvkLANYYEYD.....INEA.LNCCLL............Psarrdvhig....................................nystdhekeqIKFEIMETLGKQWHGGKgh.........eynH..................................-YDYSHVV..............RN-LRNYVEQLRKD..----..-..-----.......--------ilnkfglqsrd...................................................................
Q1D4C5_MYXXD/316-423                   ........aala----MYSDGRFPGDTEGPVHHICTSRNTISAATGGPWtpe.............cerIFKKAGMT.....LEDA.ANKVRL............-.......................................................-----------NGHEGP..............H..................................PEFYHNQV..............MTRLERSVVRCRTT..ESCR..A..SLLKE.......LAKIADEL..............................................................................
G8M292_CLOCD/622-718                   ........snag----VGNQGTSSTAKPTQTHHFLTNKSSTYTAQIEK-...................ITKKYGLD.....LDGS.WNKAAM............-.......................................................------------QHQGR..............H..................................PNAYHDYM..............LNEIKRIDSIAKGD..TN--..-..-----.......--------iflklfesvknev.................................................................
R5PUS9_9BACT/1-72                      ...........m-------------------------------------...................--------.....----.-NGIFL............P.......................................................--SSDRSGLRGVIHRGR..............H..................................KQEYYEYI..............EQMFSQCKSKK---..-DCY..E..-----.......--------vldkvksdlykgkiklykegtnkvnk....................................................
G2PQ73_MURRD/571-665                   .ksrfreivgai--------------SGEEAHHIIPWAWRENKVVQ---...................KAAEWGFH.....MNDK.INGIAL............-.......................................................----KKYFQGIGGVHAN..............H..................................-PAYSDYV..............LRRLNLWAKQN---..----..-..-----.......--------asftgkdavyflek................................................................
D0LIF3_HALO1/558-682                   .........vge---LLAQAGHSARPPYHQAHHVIPDEVVRTHPLFRL-...................ARERGVFD.....HDAP.ENIALL............Arsevre..........................................pgrapfvPEKVPGLSDNLPRHQGS..............H..................................-KRYTQVV..............VDIADKYTLLLKRS..GD--..-..-----.......--------qlgdinhqqlkaasda..............................................................
A0A075MLA3_9RICK/2846-2946             .......lefti------------DGKKFQEHHIISDKNKLTSEHK---...................LWEKAGID.....AQSR.KNKIYL............P.......................................................--TKEEHHPTRSIHLGG..............H..................................SKIVSEKL..............ADKMDKAINTGEMQ..GWTQ..E..QYKEA.......LHNI----ive...........................................................................
M5E2E1_9GAMM/81-186                    .....lgrflet-------VQYVRPDSNFEAHAIVSGGHARAIAARE--...................ILAQYQLR.....IDDP.TNGVWL............Pn.....................................................fKKNLSGYPDFNYAHRPL..............H..................................RKIYYLNI..............TSCLEQAMSSAHAR..VI--..-..-----.......--------lrriaqgi......................................................................
Q08Y34_STIAD/330-436                   ......pgamlm-------TAHRGRGGRTENHHIGTIANEISAVRGGPWtpr.............lreLFAKAGMR.....LKDP.ENVVPV............-.......................................................-----------KGHKGP..............H..................................PERYHRLV..............YERLDDATRGCRSI..TECR..A..RLTRV.......MDRLAQEI..............................................................................
M5DVU1_9GAMM/114-223                   ...........l-ERNMAAEGIPKPSAEHSAHHICPGKGKIPALTRMTR..................iRLHTYGVR.....INDP.ANGIYLlckdcsaphwsmP.......................................................---------ESRGHRKY..............H..................................NHDYEYLL..............WERISAMTNQDQIK..TQ--..-..-----.......LQV-----vgrim.........................................................................
B7VTS0_VIBTL/57-171                    ....wyveasek--------------VSVTGHHILSVSGVKAASKT-KYg.................tMLEAAKYD.....TNHC.KNIVAL............P.......................................................TLSQMACELEVPIHYGN..............H..................................N-------..............--------------..----..-..-----.......--------geaipdmqmgmsyhmfttkmilhmlkllrrkgtcpgdtesesqev.................................
F9TDX3_9VIBR/1-116                     ............----------------MQAHHLIPKSVFKLKNTKSKQvrekm.........mflrrIAQMCAYN.....IDFW.KNGVGL............P.......................................................NKKETACFLNKPRHSGG..............Hd...............................rnEFNYTNECvk..........laHKKLSKDLQKREDN..GSCS..K..TTNSS.......--------liakfness.....................................................................
Q81H88_BACCR/21-129                    .........leh---GGKDAGVEPPPYSNAAHHLTPWNDKRAIEAQE--...................LLKEFGIH.....HDSA.ANGVFL............P.......................................................-YKVNEYVTTEVLHIGN..............H..................................CTDYMKEV..............TKVLKEVKEYGGTQ..ADAV..A..AL---.......-HD-----irirlld.......................................................................
D3VAU8_XENNA/42-143                    ...........n-MMENMGLSRSAKWSGYQAHHVIPKELANHP------...................ALKKINYD.....IDVA.ANGIFL............-.......................................................-RKADNGVSAMARHQGN..............H..................................-HGYTDAV..............RNALDRIDLKQSKE..AISK..Q..VAN--.......IQDIAK--k.............................................................................
Q1DCQ9_MYXXD/116-240                   ...kenfnptyt----------QQYPYAWEAHHMLPGSAFYYMMKDGKPafty...........kqirLLLMSEYN.....INHG.HNIINL............P.......................................................AEDWAVPVHSLICHPSD..............H..................................-ESYTMRV..............MDEMRKVANDLQK-..----..-..-----.......--------lidsgkphgnlpelifeelkklen......................................................
B7VU40_VIBTL/30-162                    ...........n-NVKKLSDHPFNNGIHMDTHHLISAEAVKISKLGK--...................NLVNKGYD.....INQL.SNLVGF............P.......................................................ATLPGACQLHCQLHRGD..............Htfs............................rprEEPYHRYVsg..........elRDPEIRKKIKDCYG..KTKK..T..ETESEih...klL-------dpisrkvlkkinki................................................................
B7VTR6_VIBTL/40-151                    ......lgvtek-------DKMEGLEKNLQAHHIITVNEMENNDFLFK-...................KLPYLGYN.....LNDW.HNIVVL............P.......................................................GIPELVCFYEMPLDSGS..............H..................................PTPYTDNV..............KRRLSLLRNAILGS..KYCN..E..NDSKA.......LELIVKEM..............................................................................
Q1DF18_MYXXD/329-436                   .........vam---ANRGMGSGGSRGRSQEHHLATDKNSVSTARGGPWtpe.............frrLFRKAGME.....LKDP.ENVVDV............-.......................................................-----------PGHKGP..............H..................................PQEYHEAV..............YERLRDATRTCRTV..VACR..K..SLSAA.......LKELAEEV..............................................................................
A0A090IH35_9GAMM/550-678               ........cdar----------NQTSGNLQAHHVITSETVNDTKWKN--...................YRSHFEYD.....IDES.KNGVFL............P.......................................................SQTDVACQLGVAVHKGP..............Ha................................sGLDYSTVLfli........qsgKEIPDEISKGLKSS..KLT-..-..-----.......--------yiaavkrelrkitdlfkkggfcgskpdnkl................................................
D0LKQ6_HALO1/813-930                   ......vkrlyk------RLGLPSRPANHEAHHLIPDELVRKHPLLRA-...................AYERGILK.....LDGV.DNIALL............Arrd.................................................lpeEKLVAGLSEGLPRHQGP..............H..................................-PNYTKQL..............TDRADATMKDVLDG..RMLK..D..LSDEE.......LAMA----vdav..........................................................................
U9T9F5_RHIID/21-128                    .........lra---NMVAAGKSEPAFKNSAHHIVMSNSTDVRMVALQT...................KMNKLDID.....INTS.ENGIFL............Ps.....................................................nSKVKLPAGSTLPNHASI..............H..................................TNAYKQKV..............YDRLISVNNSTDFL..SE--..-..-----.......LNKINSE-i.............................................................................
K4IYI2_PSYTT/708-822                   ..........vl--SQNMNAVGKKYIKGTQAHHIIGNDSRCASSVLLKQ...................LLKTNKID.....INNA.INGMRL............Pggh................................................kdngVKAYKTTTAKGQIHKGS..............H..................................NCKYYDAV..............YEIMKNAKNQQQFI..EL--..-..-----.......LSKVKKEIys............................................................................
A0A090IHZ4_9GAMM/42-167                .......qkqnp-----ANHPWFYQSGSLQAHHIIPIQCMQKSINWEK-...................IAKTIGYD.....INHW.RNVVIL............P.......................................................ATPELACQLGVQIHSGP..............Hsag............................rygIRNYVQGV..............KQRLDDILDDIMDG..DLCE..D..SL---.......--------sdiviliddeseailrki............................................................
Q093Y1_STIAD/327-433                   ......pgavam-------AARGGRGARTEDHHIGTIANKKSTLRGGPWtpr.............ledLYARAGMR.....LKDR.ENIVPI............-.......................................................-----------PGHKGP..............H..................................PQRYHEIV..............YRRLRTALGECSTI..AECR..A..RLVPA.......LDELAK--li............................................................................
H8MWR1_CORCM/322-427                   ....amgtkgpn----------VPAPVEVRVHHIATNKWWEATHNGGPWspk.............fqeLFDRAGMS.....LDDE.VNTVRV............-.......................................................-----------RGHQGP..............H..................................PRKYHEEV..............YERLKEALGRCRSI..QRCS..E..ALVKE.......LQSMGAEI..............................................................................
G8Q7B0_PSEFL/2958-3065                 .........nln---QAMGRNRTDSWAGYQAQHLIPSELKNHP------...................ILKKVGID.....LDDS.SNGIFL............Pa.....................................................sKAKPEGAISGMPRHTGS..............H..................................-PNYTEAV..............RKSLNELDRNLPVE..QLQK..Q..-----.......--------vfdlqgrlrnvt..................................................................
F9YW06_CAPCC/8-126                     .....swyenif-------EKHAYDRLSFEAHHIIPIDVLKTNKELKKLlfd.............lkkADPNFNFD.....FNGI.DNGMMI............-.......................................................--QKKSLKLDISGHTS-..............H..................................-KDYNDAI..............SEKITEICNETDLN..NLEK..F..EEIQE......lIKNTK---tkleqe........................................................................
R5JAS2_9BACE/948-1054                  .....nnptlls--------SNKPVRIQFEKHHIIPKQLKNDPLVK---...................QAQKGGFK.....FEGK.ENKISV............-.......................................................--EKFSRATGKGQHGN-..............H..................................-PNYTKQI..............GEKISKFTKDNPHP..TPEQ..A..ANFAKe.....tTQSIREQ-i.............................................................................
S5ZZY3_9SPIO/384-498                   ........vkdp----NSWIDVFGLNNTTQSHHIISDKNNLTKNHA---...................LISLAGYKdpndfLQSS.TNKIDL............P.......................................................-TKYNTEDNVSSIHSGK..............H..................................YNIYSELI..............ADAMDEKVLLGKKE..NWTQ..D..QYKQA.......LDDITNK-v.............................................................................
A0A023Y7W8_9GAMM/1444-1555             ..........il--RRNMNREGRTVAPGQAAGHIVASTGSKGHWAAAADs................rdILSAYDIE.....INDA.ANGVPV............-.......................................................--------DHPRPHNRM..............H..................................TRKFHMDV..............KARLTAVVDRMSAA..GYGH..R..ATRSAlr...reLRQIGRE-f.............................................................................
U5MQZ0_CLOSA/41-152                    ........elsr----NLSREGRPVGNGEVAAHIVASTEEKRQWAKVADs................rkILDKYGVN.....INDA.ANGIPL............A.......................................................---------HPRPHNIT..............H..................................RAGFHEMV..............NTRLTSVVNNMTSL..NYGR..K..AIRSAlr...keIRKIGR--et............................................................................
A0A090IEA7_9GAMM/34-155                .kldkhplrvan-----------SKSIKLATHHILSIKATESLAKVRRN...................LLKMKAYD.....VNHL.KNLVTL............P.......................................................TEKQVCCHYALPRHVSG..............Htgk...........................qiavDYSFDEKT.............aEDNLTALHSAETDE..TS--..-..-----.......--------lseatlkddmhrmdel..............................................................
G8ULB1_TANFA/486-592                   ........pkgg-----WNYGNMPKIDGYQLHHVIPKSMADHP------...................AIKAAGFD.....VNKP.SNLIYL............P.......................................................--KETGIHPTRSVHDGWn...........kgH..................................-ADYNVDI..............KQKLNEIHQIGDIE..GWSK..Q..QYSDA.......IEDLR---gdt...........................................................................
M5DSZ4_9GAMM/72-180                    ........lgkf----LRISGFSRPGPKWEAHHIVSTIHREAVAMRLLI...................ADDDFSIR.....IDDP.DNGTWM............Pk....................................................tkADARATIYPDAIGHNRI..............H..................................RQRYYRWL..............ENTVTAFDDGAQVR..AF--..-..-----.......LNTVRVQ-l.............................................................................
Q1DCY3_MYXXD/320-423                   ......vgavgg----------IQGDPDGKVHHICTDKNTVSDVTGGPWtqr.............ferIFRRAEMK.....LSDS.ENLVKI............-.......................................................-----------RGHKGP..............H..................................PREYHEAV..............FERLEFATQGCRGT..ARCR..A..RLVEE.......LAKIAREL..............................................................................
D3F4T5_CONWI/1777-1905                 ........rppr----NLDGSTTGTHNGFVARHLIPPQDELELAAHLQA...................LAWSCGIT.....PNDA.RNGVWL............Rgttlk.............................................nvgdgGARRASARFRAVSNDGQdr..........ayHe...............................dlTILYYRYV..............FVRLDAARESSGNC..PTAR..A..AGI--.......LAQVRQEL..............................................................................
Q97M65_CLOAB/622-727                   .........nmf---EEMGLPRSTKRTPYQAQHIIPKDFKEHP------...................IIQKIGMD.....MDHA.SNGYFL............-.......................................................-RRPDESISPMSRHEGY..............H..................................-AVYSDFV..............ERQLNAMDINQSIN..ILEK..Q..VYDLQq.....kLRK-----lqdk..........................................................................
Q2SAG3_HAHCH/73-226                    narkvtiggktf-------------DAAVAAHHLIPGNASLKESEIMAYlhi.............dgkAAGNIGYN.....VNSM.PNGVWS............Pgnygvrpwggeg..............................kafkakhgiepkdFAFAAMDEWRCQFHDA-..............H..................................-EKYSIFV..............RGVLDKIADKLRDQ..ET--..-..-----.......--------iwcpeqkhkeqeqtqifalvsrlntvst..................................................
Q2G616_NOVAD/5-122                     .......gsvnv-------PGQPGYSPDLQRHHILPRQVLGSRALGG--...................LVARLGVDrl.gfHDFR.RNGLLL............P.......................................................ACEQAALRIGLPLHRGP..............H..................................-RSYNELV..............LERAGQIEAHWAQQ..RAAG..S..TDA--.......--------dfvalmrfdllqral...............................................................
B0X8Y0_CULQU/1642-1751                 ...esdshtvde----------AVEQKKCQKHHILHRKFKNHP------...................ALVKANFH.....IDDP.SNLIYL............Pi.....................................................sEEIRSECGTQRSIHRGR..............H..................................SNLEFNRV..............NNGLDKIYQDATAN..NWSQ..Q..ETFK-.......--------avfrfamdgr....................................................................
E3FR61_STIAD/329-436                   ..........na--VAMAARPSRGKGPCVETHHIATICNGKDTKRGGPWtpr.............frqIFAKAGMS.....MEDP.ANKMPL............-.......................................................-----------SGHYGP..............H..................................PERYHQLV..............YEELDDATATCRTV..VECR..E..GLTRA.......LKALAKEI..............................................................................
A7MQ50_CROS8/1401-1508                 ..........lr--QNMIREGIEEPSFKNSAHHIVMSNSTDARMVALRQ...................KIEDFDLD.....INGS.YNGVFL............Pt.....................................................sSKVKVASGTSLPAHSKI..............H..................................TNTYKQNV..............YERLINIDNAEEFV..SE--..-..-----.......LENISN--mi............................................................................
A1TJK5_ACIAC/3-103                     .......dndpi----------------LQSHHVIEQSFFRKHELLLK-...................LASHGLID.....EHAS.ANRLYL............P.......................................................MDGKLAEELETSPHRGR..............T..................................RSSYTDGI..............LQELDRIMDSADGV..AAMD..D..-----.......--------davalkrvsakv..................................................................
Q1DG56_MYXXD/153-287                   ...qnqlqggyg----------AFYPYEHNYHHLIPVGAVEEWVIGKGEsgspar.......sdqvvkLILISRWN.....IHNE.KNMVLL............P.......................................................QQEFEALIVGLPAHCPWgv..........paH..................................-AAYQSSLqgr.......lrklRSKIDRAIRQKKHP..KDLK..A..DIIEE.......LDSLSN--al............................................................................
Q2SPA9_HAHCH/26-132                    .......neiaf------NKNAYGTGASVEGHHLIPTEVAKEFEGFFQEia...............dhSEGHLVYN.....QDNP.SNGVYL............Pk.....................................................eKGAGKKGPNFAAVHSGS..............H..................................-PAYSEFV..............RQRLVFLQKEYSD-..----..-..-----.......--------kvailanq......................................................................
E3FLQ2_STIAD/25-135                    ...sgksareaa---------AARIGAGDQLHHLIPDVVAQRHPLIRQA...................LDRLEGYT.....IDRG.TNILDM............P.......................................................---VVPNVEGKILHLGS..............H..................................-PEYNKYV..............ISKLDDAVGRLGP-..----..-..-----.......--------lsklapstiegvllkvedal..........................................................
H8MRJ0_CORCM/290-393                   .......gpggg---------GIQGDPEGDVHHICTDKNEVSEQSGGPWtpi.............fedLFQTAGMK.....LSDA.ANQVRI............-.......................................................-----------QGHRGP..............H..................................PREYHAEV..............LRRLRLVMQGCQET..GQCR..A..ALVDE.......LARIAKEL..............................................................................
C5BUJ2_TERTT/115-225                   ...........l-EMYMRAEGVPKPSSQHTAHHICPGSGRWEKNLIRNTr.................iHMHSHGVR.....INDP.ANGVYLlhkddytphysmP.......................................................---------NSRGHLTY..............H..................................TREYEKLV..............AGRISTLPSRDVIK..TQ--..-..-----.......LQVI----grll..........................................................................
H8MYF1_CORCM/267-370                   ......pnavam----------SSRSGKPQRHHLATIRNEKSSKTGGPWtpl.............frkLFKKAGME.....LKDP.ENIVEV............-.......................................................-----------PGHRGP..............H..................................PAEYHRRV..............MRRLLDATEQCRTV..TQCR..D..ALTGA.......LKELAEE-a.............................................................................
B7VTP2_VIBTL/9-135                     ........naie----GDHDHPLNCGVPMQIHHLLSKKGAIESGNKS--...................ILESYGYD.....INEI.GNLVAL............P.......................................................STFAGACHLEIQLHRGN..............Hisfs.........................nsdddDELYHDYVqk..........lmVKTLKKIEKECEEG..SAKK..V..QSR--.......MNSK----skvllsdm......................................................................
K9VSJ6_9CYAN/116-228                   ....ergninqn--------IAGGVPSGYQGHHLIPVKVAQEFPVMQE-...................AADNLGYN.....INRG.NNGIAL............P.......................................................GTPAESLSTGLPYHGGR..............H..................................TPEYNDLA..............RGYLDNLQRRYDRG..LVSD..S..DLVNE.......IANVENQI..............................................................................
I0DRL7_PROSM/92-198                    ......laasgd-------YKEMPVMPGFQKHHNIPQSMANHP------...................AIISSGYD.....INNS.QNITQL............P......................................................sSKTAIEQNPERTVHRGG..............H..................................NKAYDSYI..............SNELDKIHANNASP..EIKR..M..QIQ--.......--------alsddvgnr.....................................................................
A0A097QLK6_9VIBR/19-131                .......savkr------KHPLNFMDRAIASHHIISCEATRRLSSYRRK...................QITYKGYD.....VNHP.WNLVIL............P.......................................................MKDRIACHYQMPLHKSG..............H..................................KD------..............--------------..----..-..-----.......--------eaiithyekskgvsvsglqkelqaeahqegdqhkqkvf........................................
Q9KAE6_BACHD/142-247                   ...........n-MMEEMGLKRSTRWSGYQAQHIIPSEMANNP------...................VIRKVGMD.....LDNA.SNGIFL............-.......................................................-RIPDNDISTLSRHRGY..............H..................................-SVYNEVV..............ERALNRMDINQSVD..SLQK..Q..VY---.......--------dlqqnlkilqek..................................................................
Q2S6Q8_HAHCH/144-267                   ......ikkghn-------FTRETWPYWNNAHHLISKGTFKNMILNEGPkisn...........iiqkALLTAKYN.....IHHK.KNVLLM............P.......................................................QDKEVAQILGLPRHLVLkeedqqevskqctsH..................................-PVYDRLV..............RET-----------..----..-..-----.......--------kkglreildgyrelcdpvk...........................................................
F9YVS2_CAPCC/181-290                   .......yayvh------DVNGWMDVFGLDLHHIIPQSVWKSINKNYDNvlk............nidgYVQNVSKK.....AKDI.SNLIDL............-.......................................................---------DKPFHGN-..............H..................................-PKYNEYV..............NERIKDLIKNNDLN..LKSI..K..ELQEE......lVNH-----indamk........................................................................
A0A0B5EV03_9ACTN/1434-1544             ........rlrr----ALRAEGRGPTRGQAAAHLVPSGGTHGHWAPGANs................raLLGRYGVD.....VNEA.ANGIPL............-.......................................................------------GHPSP..............Hny..............................thRQQFLQRL..............DDRLQQVASQASRL..GAT-..-..-----.......--------pqqigdslrgelrrigge............................................................
Q1DAJ7_MYXXD/86-211                    ..galeefevei---------------GATPHHIIPGKASMAKSRLEQWtra............ekgkIKEDIGYS.....IDCA.RNGVFL............Pklpdlygtkhkvpgvtm....................aqfygqtwralspaskegVGFLVMKDTWLQLHYTD..............H..................................SKPY----..............--------------..----..-..-----.......--------ktsptmnydke...................................................................
E3FUQ4_STIAD/250-333                   pgavamtvrggp------------------------------------Wtpl.............feeLFAKVGMR.....LKDP.ENIVPL............-.......................................................-----------KGHKGP..............H..................................PRRYHEIV..............YERLQEALGDCRSI..VECR..T..DLTRE.......LRSLADEI..............................................................................
Q6CZ60_PECAS/11-112                    ...........n-MMEKMGLPRSTTWKGYQAHHVIPKELANHP------...................ALKKINYY.....IDDA.SNGIFL............-.......................................................-RTKDDAISAMARHQGN..............H..................................-SGYTESI..............RSALGKIDLNQSAS..SISK..Q..VSD--.......IQNIAR--g.............................................................................
H8GU39_DEIGI/821-937                   .........qad---PNAIQDLNFGRDGHTLHHAIPDKVSTSDPLCVK-...................AMQLTGYS.....PDRM.SNYHPM............P......................................................mERLYRQLDGQEVGHWSS..............H..................................-AEYDQTVvr..........paLRDSMRLLETEFGA..AGTW..T..ADHPR.......IADL----rtai..........................................................................
Q16LV5_AEDAE/1611-1719                 ........irrd-----SNSMEHAMTNQTQEHHLIHQTLKTHK------...................AITESGFH.....IHDP.INVIVC............Pk.....................................................sEEIRQQLGTNRSVHCGR..............H..................................PKELVREL..............RGKLEVAWNLHKNN..RVAL..K..AAVYE.......IAYSERE-l.............................................................................
B7VTQ4_VIBTL/18-146                    .........dsk---AKKHHPLNFKLRSVASHHVVSCDSLSRLSEARQQ...................QIVRKGYD.....VNHQ.KNLVIL............P.......................................................TVDEISCQYSVPLHKSG..............Htd.............................sdlIAHYEDRT..............GEEVEADLASLATA..PASR..E..SI---.......--------qedvislnaalgyhkvvakkl.........................................................
H8MXW0_CORCM/310-417                   .........aal---AMYGQGRFPGDETGPVHHICTNKNPVSAASGGPWtpr.............cedVFRKAGMT.....LEDA.ANKVRL............-.......................................................-----------NGHEGP..............H..................................PGQYHEKV..............VLRLERAVFRCRST..ESCR..S..RLMTE.......LAKIANEL..............................................................................
D0LZ57_HALO1/238-363                   .........vge---LLARAGHTARPPHHQAHHVIPDEVVRKHPLFRL-...................ARERGVFD.....HDAP.ENIALL............Arrevre..........................................pgrapfvPEKIPGLSDGLPRHQGP..............H..................................-DTYSQLV..............MDIADDALDDIKQQ..SLRL..Q..DLSDT......aIESLTR--di............................................................................
Q6LMQ8_PHOPR/26-149                    .....tnvkiip-------SHPFNHGIHMDTHHLISKEAVNISKLGK--...................LLVKKGFD.....INDL.NNLVGF............P.......................................................ATLPGACQLKTQLHRGD..............Hifk............................ppgEEPYHDEV..............SNALLEVIEKIEQCygKTRQ..K..EQSDEih...qlLNPIAK--si............................................................................
D0LTA7_HALO1/753-880                   ......tlleaa---------GVAKPAHHQAHHILPIQLFREHELLRE-...................ALRRGIVS.....PDAV.DNLVLL............Artevrq..........................................pgkasiiPEKVAGVSEGLPRHQGP..............H..................................-RLYTDMV..............RTEANDVMDELLQG..RTLR..E..FKDDK......aL-------agavaelqqrar..................................................................
K4KH34_SIMAS/77-181                    ..........gg---HMETSGYDKPADHFHAHAIVSGGHKRAYAARE--...................ILAQFNIR.....IDEP.ANGLWL............Pn.....................................................yKKNLHLSPIFDCAHGNI..............H..................................NKIYYLNI..............TACLEQAMSQQHAR..EI--..-..-----.......LRR-----vaqgi.........................................................................
Q1D471_MYXXD/90-212                    ..........ag--RESSEHPWYTGRWSIAAHHLICSEAMADDENWAR-...................FCREFGYD.....INRR.ENGVML............P.......................................................MVLAVACELHVPVHIGP..............Hsggw..........................afdmDMAYPDAV..............KGALEAVADAVERG..DYCQ..KpaALTQS.......LDRISRQI..............................................................................
Q1DE13_MYXXD/325-431                   ...pnavamaar----------GMSGGHTEDHHLATNKNSVSTARGGPWtpk.............fekIFRKAGME.....LKDP.ENIVPI............-.......................................................-----------PGHKGP..............H..................................PQEYHDLI..............HERLYDATRRCRNV..SECR..E..ALTRA.......LRRLAAE-t.............................................................................
F2NX86_TRES6/286-404                   ........dfie-----KLYNDFGPKKTMQDHHWIEKSRIGKKKYQ---...................FLKNPPMKi..nlYDDK.KNLSLI............-.......................................................-----------VGHNGS..............H..................................KNTYNLLL..............DTNLDRITKSLEQE..SLKR..K..LSIKE.......L-------fqeektikwinenvgkvitdmqntv.....................................................
D8MMS3_ERWBE/1397-1498                 ..........nm--MASMGLKRSTKWSGYQAHHVIPKEFSDHI------...................VLKKIGYD.....IDDA.TNGIFL............-.......................................................-RQVDDGVSPMARHQGN..............H..................................-HGYSSAI..............ENALNNLDPNQSVD..VLKK..Q..V--SA.......LQNVAK--r.............................................................................
U5MMI8_CLOSA/91-206                    ..........rg--ELKTSGNMQTPPYGNAAHHIVAAKEEDAKIARD--...................ILKEYSVD.....VNSA.SNGVFL............Py.....................................................gKKETNSYITTETTHNGS..............H..................................TGDYYKYV..............NNKLQQTIEEIETN..GGTVtsK..DITKT.......LDDIRK--gl............................................................................
A7GLS5_BACCN/1-104                     .........mmt----EMGLRRSTKWSGYQAQHIIPAEMADNP------...................VIKKIGMN.....FDDS.SNGIFL............-.......................................................-RVPDDNISTMARHRGY..............H..................................-SVYNEVV..............ARALNKMDINQSID..SLQK..Q..VYD--.......LQ------knlrklqg......................................................................
D3VA39_XENNA/1335-1436                 ...........n-MMENMGLSRSAKWSGYQAHHVIPKELANHP------...................ALKKINYD.....IDVA.ANGIFL............-.......................................................-RKADNGVSAMARHQGN..............H..................................-HGYTDAV..............RNALDRIDLKQSKE..AISK..Q..VAN--.......IQDIAK--k.............................................................................
F2NX75_TRES6/163-287                   ........ldfi----EKLYNDFGPKKTMQDHHWIEKSRIGKKKYQ---...................FLKNPPMKi..nlYDDK.KNLSLI............-.......................................................-----------VGHNGS..............H..................................KNTYNLLL..............DTNLDRITKSLEQE..SLKR..K..LSIKE.......L-------fqeektikwinenvgkvitdmqntvkkdht................................................
R7CZP8_9BACE/743-860                   ...erirrylgm------------PKRQVEPHHVIPSNPVTETGRKARE...................IWVKYFDS.....VDHP.CNGIWL............-.......................................................GRNNKKLGYKALAKGSN..............Hs...............................pnSIEYEQKV..............STALLNTYNKYQKQ..YAKN..P..EMMQQvl..aetVDNIKKQL..............................................................................
R6CII2_9BACE/1-58                      .........mgk-------------------------------------...................ITNKYGLK.....LDES.WNKEML............P.......................................................-------------HLGR..............H..................................PNAYYEWV..............LEQMKQIDAMPCKG..----..-..-----.......--------tdslwnqqd.....................................................................
N8YFR2_9GAMM/29-131                    ......skelgk------NVTGQCSWSGKQAHHLIPETLENNQ------...................LLKDIDFK.....MNSA.SNGIML............P.......................................................----ETPNAYISEHIGG..............H..................................-AIYTKAV..............ERELNHIGKKYVNE..GDRK..R..A----.......VQDLQR--nldsal........................................................................
Q97IJ7_CLOAB/201-306                   .........nyl---KKKRGNPPSGMSKPHAHHVAVKGNFSNRKKIIQTyak............ysseVLKSVGID....pYYGI.ENIHWA............P.......................................................-------------NEG-..............H..................................SNRYIKAI..............AKEFYEVKKLGGNK..DDFV..N..-----.......--------kildivdklrk...................................................................
H8MHW8_CORCM/326-427                   ....navamssr--------------GDSQKHHLATIRNNVSTQRGGPWtpr.............fqrIFKKAGME.....LKDP.ENVVEV............-.......................................................-----------PGHRGP..............H..................................PQRYHQRV..............YDRLEQATRGCRSV..EQCR..E..ALVAE.......LRKLAQE-a.............................................................................
Q1CWH6_MYXXD/114-220                   ....asgrwpws----------------NNAHHIIPVDDVLSKVLNFDQl.................kLLQQAKYN.....VNKG.VNIIYL............P.......................................................NSTRHAQLFQLLKHPKY..............H..................................-STYSKDV..............RTRVNAIRDQLTQA..TDED..E..AGHPK.......LNE-----ktvpl.........................................................................
A0A0A7PGU8_9SPHN/3-117                 ........grgw-------YGAPPPQTGFQRHHLIPFALMQRPQMEAMF..................eELHTEGFA.....LQNFgRNGLML............P.......................................................ASEPAALRSGHALHRGP..............H..................................-HGYSDVI..............TARVERIRA-----..----..-..-----.......--------hftlhasadlraarrtavmrlrllqd....................................................
D0LNH0_HALO1/697-823                   .........vge---LLAQAGHTARPPYHQAHHVIPDEVVRTHPLFRL-...................ARERGVFD.....HDAP.ENIALL............Arsevre..........................................pgrapfvPEKVPGLSEGLPRHQGP..............H..................................-DNYSQLI..............MDIADDAKEAIGEQ..GLRL..E..DLSPE......aLQSLT---ykvl..........................................................................
R7RAP8_9FIRM/94-203                    .......glgrm-------PSWMTTRKGWQRHHLIPVSVWDKY--F---...................IPQEAGMN.....VNGA.TNMTYL............P......................................................vAQGIDLVNPNSSLHVGWn...........nvH..................................-SEYNQYI..............SQELGKISRLAKEN..NWGK..R..KIQKE.......IRMLQSE-v.............................................................................
I0DWQ7_PROSM/1442-1548                 .........kls---RNMVAAGTPRPANSAAHHIVGDTSKGAKPARD--...................ILKKHGID.....IDDA.SNGVFL............P.......................................................NKNNIDESLSGIKHNGR..............H..................................PSNYIDAV..............NERIIQADLTGGKQ..GVLD..E..-----.......LSNIRN--il............................................................................
E3FGA3_STIAD/311-416                   .....avamysn---------DIRGDSEGPVHHICTNKNLASAASGGPWtpq.............cekIFKKAGMS.....LEDA.ANKVRL............-.......................................................-----------NGHEGP..............H..................................PERYHKEV..............VDRLERAVERCRTT..ETCR..I..KLMRE.......LANISDEL..............................................................................
U4K522_9VIBR/110-232                   ........lasn----LAAIGEPKPTKNHEAHHIIPGKGRYRQDELMNVr.................lNLHAYGYG.....INDP.LNGVWL............Vnf...................................................kkNKQLNWEAPKSPGHRES..............H..................................RYNYETWIiskfmldtlpkevfTNRLVDVKKRLK--..----..-..-----.......--------ngshpaqil.....................................................................
F9YW08_CAPCC/2-107                     .......kydlg------------EPLNFEVHHIIPINVLEKNKALQDLfl...............waEQNGKKFD.....FNGL.DNGIPL............-.......................................................--QKKRLKYGVNGHAK-..............H..................................-PDYDKAI..............IPKIESITNSNLTN..EKKL..E..AIQGI.......VNKA----kekl..........................................................................
#=GC seq_cons                          ..........ht..............hthpsHHllsppshppt.hh......................hhpphuhc.....lsss.pNtlhL............s.................................................................hshHpGs..............H...................................ptYpchV..............tppLpphtpptptt..t.tt..t..............lt......h.............................................................................
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