GenomeNet

Database: Pfam
Entry: AKAP7_RIRII_bdg
LinkDB: AKAP7_RIRII_bdg
Original site: AKAP7_RIRII_bdg 
#=GF ID   AKAP7_RIRII_bdg
#=GF AC   PF10470.8
#=GF DE   PKA-RI-RII subunit binding domain of A-kinase anchor protein
#=GF AU   Buljan M, Coggill P
#=GF SE   TreeFam_TF105406
#=GF GA   22.70 22.70;
#=GF TC   23.10 22.70;
#=GF NC   22.00 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12804576
#=GF RT   AKAP7gamma is a nuclear RI-binding AKAP. 
#=GF RA   Brown RL, August SL, Williams CJ, Moss SB; 
#=GF RL   Biochem Biophys Res Commun. 2003;306:394-401.
#=GF RN   [2]
#=GF RM   16483255
#=GF RT   High-affinity AKAP7delta-protein kinase A interaction yields
#=GF RT   novel protein kinase A-anchoring disruptor peptides. 
#=GF RA   Hundsrucker C, Krause G, Beyermann M, Prinz A, Zimmermann B,
#=GF RA   Diekmann O, Lorenz D, Stefan E, Nedvetsky P, Dathe M, Christian
#=GF RA   F, McSorley T, Krause E, McConnachie G, Herberg FW, Scott JD,
#=GF RA   Rosenthal W, Klussmann E; 
#=GF RL   Biochem J. 2006;396:297-306.
#=GF DR   INTERPRO; IPR019511;
#=GF CC   AKAP7_RIRII_bdg is the C-terminal domain of the cyclic
#=GF CC   AMP-dependent protein kinase A, PKA, anchor protein AKAP7. This
#=GF CC   protein anchors PKA, for its role in regulating PKA-mediated
#=GF CC   gene transcription in both somatic cells and oocytes, by binding
#=GF CC   to its regulatory subunits, RI and RII, hence being known as a
#=GF CC   dual-specific AKAP [1]. The 25 crucial amino acids of
#=GF CC   RII-binding domains in general form structurally conserved
#=GF CC   amphipathic helices with unrelated sequences; hydrophobic amino
#=GF CC   acid residues form the backbone of the interaction and hydrogen
#=GF CC   bond- and salt-bridge-forming amino acid residues increase the
#=GF CC   affinity of the interaction [2]. The N-terminus, of family
#=GF CC   AKAP7_NLS, carries the nuclear localisation signal.
#=GF SQ   122
#=GS G1RVY0_NOMLE/372-429       AC G1RVY0.2
#=GS E7FAL2_DANRE/366-414       AC E7FAL2.1
#=GS A0A093IF44_EURHL/6-63      AC A0A093IF44.1
#=GS A0A091JKZ5_9AVES/161-218   AC A0A091JKZ5.1
#=GS S7PFN5_MYOBR/26-72         AC S7PFN5.1
#=GS AKA7G_RAT/294-351          AC Q6JP77.1
#=GS AKA7G_RAT/294-351          DR PDB; 3J4Q A; 294-317;
#=GS AKA7G_RAT/294-351          DR PDB; 3J4R A; 294-317;
#=GS A0A091LZ61_CARIC/7-64      AC A0A091LZ61.1
#=GS M3WSN8_FELCA/11-56         AC M3WSN8.1
#=GS A0A091D9B7_FUKDA/328-385   AC A0A091D9B7.1
#=GS J9NW88_CANLF/11-58         AC J9NW88.1
#=GS F7IC49_CALJA/22-79         AC F7IC49.1
#=GS A0A093L5I9_FULGA/6-63      AC A0A093L5I9.1
#=GS A0A099ZB90_TINGU/10-67     AC A0A099ZB90.1
#=GS A0A096NC89_PAPAN/11-56     AC A0A096NC89.1
#=GS A0A091VL22_NIPNI/6-63      AC A0A091VL22.1
#=GS A0A091NPL3_APAVI/40-97     AC A0A091NPL3.1
#=GS A0A091VTH0_OPIHO/6-63      AC A0A091VTH0.1
#=GS H0ZN63_TAEGU/216-273       AC H0ZN63.1
#=GS J3KN37_HUMAN/25-82         AC J3KN37.1
#=GS F6ZQQ1_MACMU/45-102        AC F6ZQQ1.1
#=GS A0A091P9S6_9PASS/11-67     AC A0A091P9S6.1
#=GS H2QTQ9_PANTR/267-324       AC H2QTQ9.1
#=GS A0A093EKE0_TYTAL/7-64      AC A0A093EKE0.1
#=GS H3ASR7_LATCH/372-427       AC H3ASR7.2
#=GS A0A093GY89_TYTAL/6-62      AC A0A093GY89.1
#=GS S7P656_MYOBR/264-321       AC S7P656.1
#=GS A0A091T8D7_PHALP/7-64      AC A0A091T8D7.1
#=GS G1MNW5_AILME/9-56          AC G1MNW5.1
#=GS H0XR10_OTOGA/20-77         AC H0XR10.1
#=GS A0A091JCW0_9AVES/6-63      AC A0A091JCW0.1
#=GS A0A0A0MXX1_RAT/293-350     AC A0A0A0MXX1.1
#=GS A0A091HFF6_BUCRH/7-64      AC A0A091HFF6.1
#=GS J3KS16_HUMAN/18-60         AC J3KS16.1
#=GS A0A091HIR9_CALAN/192-249   AC A0A091HIR9.1
#=GS A0A093CG83_9AVES/7-66      AC A0A093CG83.1
#=GS H2UJZ8_TAKRU/253-312       AC H2UJZ8.1
#=GS AKA7A_HUMAN/45-102         AC O43687.4
#=GS L9KYD1_TUPCH/11-66         AC L9KYD1.1
#=GS G3R0A1_GORGO/283-340       AC G3R0A1.1
#=GS I3MQZ9_ICTTR/232-289       AC I3MQZ9.1
#=GS AKAI1_HUMAN/11-54          AC P0CW23.1
#=GS AKA7G_MOUSE/255-312        AC Q7TN79.2
#=GS A0A091N0B4_9PASS/47-104    AC A0A091N0B4.1
#=GS A0A091H515_9AVES/6-63      AC A0A091H515.1
#=GS G1NKF9_MELGA/45-102        AC G1NKF9.1
#=GS A0A094LDX8_ANTCR/7-64      AC A0A094LDX8.1
#=GS A0A091VX16_OPIHO/192-249   AC A0A091VX16.1
#=GS A0A091FM34_CORBR/216-273   AC A0A091FM34.1
#=GS A0A091T1U7_9AVES/7-64      AC A0A091T1U7.1
#=GS A0A091EUM4_CORBR/6-63      AC A0A091EUM4.1
#=GS F7B585_MONDO/462-519       AC F7B585.2
#=GS F7I9X3_CALJA/267-324       AC F7I9X3.1
#=GS F7DE14_CALJA/11-55         AC F7DE14.1
#=GS A0A091SEE5_9GRUI/6-63      AC A0A091SEE5.1
#=GS A0A091PTJ5_HALAL/6-63      AC A0A091PTJ5.1
#=GS A0A0D9RYC8_CHLSB/11-56     AC A0A0D9RYC8.1
#=GS A0A087XXN2_POEFO/441-505   AC A0A087XXN2.2
#=GS A0A093I986_STRCA/192-251   AC A0A093I986.1
#=GS A0A0Q3Q507_AMAAE/11-68     AC A0A0Q3Q507.1
#=GS A0A093G0Q5_GAVST/7-65      AC A0A093G0Q5.1
#=GS A0A0A0A8J8_CHAVO/192-249   AC A0A0A0A8J8.1
#=GS G3VFW8_SARHA/22-79         AC G3VFW8.1
#=GS G1P715_MYOLU/283-340       AC G1P715.1
#=GS A0A091RZL1_NESNO/6-63      AC A0A091RZL1.1
#=GS A0A094KEE9_ANTCR/6-63      AC A0A094KEE9.1
#=GS A0A093PVZ0_9PASS/214-271   AC A0A093PVZ0.1
#=GS A0A091HCX3_BUCRH/6-63      AC A0A091HCX3.1
#=GS H2PKB8_PONAB/267-324       AC H2PKB8.2
#=GS A0A099YYQ9_TINGU/192-249   AC A0A099YYQ9.1
#=GS F7IC71_CALJA/23-80         AC F7IC71.1
#=GS A0A091KMU0_9GRUI/7-64      AC A0A091KMU0.1
#=GS M3YT80_MUSPF/258-315       AC M3YT80.1
#=GS G1KYP3_ANOCA/7-65          AC G1KYP3.1
#=GS A0A091HQQ2_CALAN/6-63      AC A0A091HQQ2.1
#=GS G3HT52_CRIGR/9-57          AC G3HT52.1
#=GS F6ZQQ8_MACMU/267-324       AC F6ZQQ8.1
#=GS S9WLG8_CAMFR/34-90         AC S9WLG8.1
#=GS A0A093H3L1_STRCA/6-63      AC A0A093H3L1.1
#=GS G3RN25_GORGO/10-54         AC G3RN25.1
#=GS A0A091TUY1_PHALP/9-66      AC A0A091TUY1.1
#=GS A0A087R6E3_APTFO/145-202   AC A0A087R6E3.1
#=GS A0A087RBG5_APTFO/6-63      AC A0A087RBG5.1
#=GS H2RG99_PANTR/11-68         AC H2RG99.1
#=GS A0A091URR6_NIPNI/192-249   AC A0A091URR6.1
#=GS R7VY68_COLLI/11-68         AC R7VY68.1
#=GS A0A091MZZ8_APAVI/6-63      AC A0A091MZZ8.1
#=GS F7IRN7_CALJA/289-346       AC F7IRN7.1
#=GS A0A091RTK4_NESNO/7-64      AC A0A091RTK4.1
#=GS A0A094NK70_9AVES/7-64      AC A0A094NK70.1
#=GS K7FYI7_PELSI/258-315       AC K7FYI7.1
#=GS A0A093CME8_TAUER/6-63      AC A0A093CME8.1
#=GS A0A091S9E8_9GRUI/192-249   AC A0A091S9E8.1
#=GS G3TSA7_LOXAF/24-81         AC G3TSA7.1
#=GS AKA7A_MOUSE/22-79          AC O55074.4
#=GS M3ZY69_XIPMA/453-517       AC M3ZY69.1
#=GS U3JUZ0_FICAL/11-68         AC U3JUZ0.1
#=GS A0A091R303_MERNU/7-66      AC A0A091R303.1
#=GS G7PWF2_MACFA/10-55         AC G7PWF2.1
#=GS G1SA96_NOMLE/10-53         AC G1SA96.1
#=GS A0A087VLR4_BALRE/7-64      AC A0A087VLR4.1
#=GS G5C774_HETGA/236-293       AC G5C774.1
#=GS F6YG35_HORSE/267-324       AC F6YG35.1
#=GS G1M3N8_AILME/22-79         AC G1M3N8.1
#=GS Q5RIX0_DANRE/66-114        AC Q5RIX0.2
#=GS G1T6I1_RABIT/272-329       AC G1T6I1.2
#=GS R4GI69_CHICK/11-68         AC R4GI69.1
#=GS I3ND12_ICTTR/10-65         AC I3ND12.1
#=GS W5P194_SHEEP/6-47          AC W5P194.1
#=GS A0A0A0A5C5_CHAVO/6-63      AC A0A0A0A5C5.1
#=GS A0A0F8CTS1_LARCR/943-1004  AC A0A0F8CTS1.1
#=GS H3D040_TETNG/254-313       AC H3D040.1
#=GS U3KB21_FICAL/22-79         AC U3KB21.1
#=GS A0A093QY37_PHACA/7-64      AC A0A093QY37.1
#=GS E2RMB3_CANLF/267-324       AC E2RMB3.2
#=GS A0A0D9RVQ3_CHLSB/289-345   AC A0A0D9RVQ3.1
#=GS A0A094KDR0_9AVES/9-66      AC A0A094KDR0.1
#=GS G7P361_MACFA/267-324       AC G7P361.1
#=GS G3UUN3_MELGA/6-63          AC G3UUN3.1
#=GS F7IC51_CALJA/45-102        AC F7IC51.1
#=GS A0A091G8X8_9AVES/215-272   AC A0A091G8X8.1
#=GS AKA7G_HUMAN/289-346        AC Q9P0M2.2
#=GS AKA7G_HUMAN/289-346        DR PDB; 4ZP3 M; 49-76;
#=GS AKA7G_HUMAN/289-346        DR PDB; 4ZP3 R; 48-74;
#=GS AKA7G_HUMAN/289-346        DR PDB; 4ZP3 O; 48-74;
#=GS AKA7G_HUMAN/289-346        DR PDB; 4ZP3 N; 48-75;
#=GS AKA7G_HUMAN/289-346        DR PDB; 4ZP3 P; 51-80;
#=GS AKA7G_HUMAN/289-346        DR PDB; 4ZP3 Q; 48-74;
#=GS A0A093Q7A1_9PASS/6-62      AC A0A093Q7A1.1
G1RVY0_NOMLE/372-429                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
E7FAL2_DANRE/366-414                  sa--PDDEELLSLSKRLVEDAVLRAMQQYMEET.QQNgA.A.HTD...--.-----------------qahsklnst...............
A0A093IF44_EURHL/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RAN..sGT.SLQLERGKLTKKHE---kk......................
A0A091JKZ5_9AVES/161-218              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGNKNESDN........................
S7PFN5_MYOBR/26-72                    .n-EPEEVRLQNASKQIVQNAILQAVRQVSQES.RQReE.R.DGD...--.-----------------nrgsfql.................
AKA7G_RAT/294-351                     ..KEPEDAELVRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GN.SVKAEEGDRNG-DGSDNn.......................
#=GR AKA7G_RAT/294-351          SS    ..SSSS---STTHHHHHHHHHHHHH-XXXXXXX.XXX.X.X.XXX...XX.XXXXXXXXXXX-XXXXXX.......................
A0A091LZ61_CARIC/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PMKSEEAASGSKNESDN........................
M3WSN8_FELCA/11-56                    .n-EPEEVKLQKASKQIVQHAILQAVQQVSQES.RQR.EdR.TG-...--.-----------------dnqgnfq.................
A0A091D9B7_FUKDA/328-385              ..GEPDDAELVKLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GS.SVKAEEADRSG-SGSDNn.......................
J9NW88_CANLF/11-58                    .n-EPEEVKLQKASKQIVQNAILQAVQQVSQES.QQR.G.E.RTS...--.-----------------dsrgslqlg...............
F7IC49_CALJA/22-79                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
A0A093L5I9_FULGA/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A099ZB90_TINGU/10-67                .p-EQDEVRLQNASKQIVQMVILRAVQQVSQES.QQK.E.R.RTH...GS.VS---------------lqlergkltkkhekk.........
A0A096NC89_PAPAN/11-56                .n-EPEEVKLQNASKQIVQNAILRAVQQVSQES.QRR.E.E.R--...--.-----------------isdnqghiq...............
A0A091VL22_NIPNI/6-63                 ..AEQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.QSN...SS.TSRQLERGK--------ltkkhekk................
A0A091NPL3_APAVI/40-97                ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNESDN........................
A0A091VTH0_OPIHO/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQQ.E.K.RTN..sSA.SLQLERGKL--------tkkhekk.................
H0ZN63_TAEGU/216-273                  ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.S.R.QTD...GS.PAKTEEAASSNKNESDN........................
J3KN37_HUMAN/25-82                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
F6ZQQ1_MACMU/45-102                   ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
A0A091P9S6_9PASS/11-67                .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.LTN...--.-----------------sttniqlergklmkkhek......
H2QTQ9_PANTR/267-324                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
A0A093EKE0_TYTAL/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNEGDN........................
H3ASR7_LATCH/372-427                  .v-EPDDAELVSLSKRLVENAVLRAVQQYLEET.QNK.S.K.RTD...SS.PAKSEEAANSN-DN---sk......................
A0A093GY89_TYTAL/6-62                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...ST.SLQLERGKLTKKHE---kk......................
S7P656_MYOBR/264-321                  ..GEPDDAELVKLSKRLVENAVLKAVQQYLEET.QNK.H.K.PGD...GS.TVKTEEADRNGTDNDN-r.......................
A0A091T8D7_PHALP/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASSSKNESNN........................
G1MNW5_AILME/9-56                     .s-EPEEVKLQKASKQIVQNAIQQAVQQVSQES.RQR.G.E.R--...--.-----------------ardsrgslqlg.............
H0XR10_OTOGA/20-77                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLDET.QNK.N.K.PGE...GS.SVKTEEADRNGHDSENN........................
A0A091JCW0_9AVES/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A0A0MXX1_RAT/293-350                ..KEPEDAELVRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GN.SVKAEEGDRNG-DGSDNn.......................
A0A091HFF6_BUCRH/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PMKTEEAASSSKNESGN........................
J3KS16_HUMAN/18-60                    .n-EPEEVKLQNASKQIVQNAILQAVQQVSQES.QRR.E.E.R--...--.-----------------isdnrd..................
A0A091HIR9_CALAN/192-249              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PLKTEEAVSGSKNENDN........................
A0A093CG83_9AVES/7-66                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNEND-sdn.....................
H2UJZ8_TAKRU/253-312                  .s-EPDEAELLRVSKRLVEDAVSRALQQYKQETlQNG.G.G.PQA..pGN.AEETVTK----------tgttansttd..............
AKA7A_HUMAN/45-102                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
L9KYD1_TUPCH/11-66                    .n-EPEEVKLQNASRQIVHNAILQAVRQVSQES.QQR.EeR.TRD...G-.-----------------rgslqlgvgeltkkh.........
G3R0A1_GORGO/283-340                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
I3MQZ9_ICTTR/232-289                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.LGE...GS.SVKIEEAERNG-NDSDNn.......................
AKAI1_HUMAN/11-54                     .n-EPEEVKLQNASKQIVQNAILQAVQQVSQES.QRR.E.E.R--...--.-----------------isdnrdh.................
AKA7G_MOUSE/255-312                   ..REPEDAELVRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GN.STKAEEGDRNG-DGSDNn.......................
A0A091N0B4_9PASS/47-104               ..AEPDDAELLSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PAKTEEAASSSKNESD-r.......................
A0A091H515_9AVES/6-63                 .t-EQDEVKLQNASKQIVQTAILRALQQVSQET.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
G1NKF9_MELGA/45-102                   ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.A.R.QTD...GS.PLKAEEAASGTKNESNN........................
A0A094LDX8_ANTCR/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEAAAGDCKNETDN........................
A0A091VX16_OPIHO/192-249              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKHESDN........................
A0A091FM34_CORBR/216-273              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.S.R.QTD...GS.PAKTEEAASGSKNESDN........................
A0A091T1U7_9AVES/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASSSKNESDN........................
A0A091EUM4_CORBR/6-63                 .t-EQDEVKLQIASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN..tSA.SLQLERGKLT-------kkhekk..................
F7B585_MONDO/462-519                  ..REPDDAELVRLSKKLVENAVLKAVQQYLEET.QNK.T.R.QVD...GS.PVKAEEPMQSDRNDSDN........................
F7I9X3_CALJA/267-324                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
F7DE14_CALJA/11-55                    .n-EPEEVKLQNASKQIVQNAILQAMRQVSQES.QHR.E.E.R--...--.-----------------isdsrggi................
A0A091SEE5_9GRUI/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A091PTJ5_HALAL/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A0D9RYC8_CHLSB/11-56                .n-EPEEVKLQNASKQIVQNAILQAVQQVSQES.QRR.E.E.R--...--.-----------------isdnqghiq...............
A0A087XXN2_POEFO/441-505              .s-EPDEAELLRVSRRLVEDAVSRALQQYKQETlQNG.G.G.PNAaalQT.PGSTEETKT--------dttansstdnr.............
A0A093I986_STRCA/192-251              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.S.K.QTD...GS.PVKTEEAASGSKSENENdn......................
A0A0Q3Q507_AMAAE/11-68                .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A093G0Q5_GAVST/7-65                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNESD-dn......................
A0A0A0A8J8_CHAVO/192-249              ..AEPDDAELLSLSKRLVENAVLKAVQQYLEET.QSK.T.R.QTD...GS.PAKTETAASGSKNESDN........................
G3VFW8_SARHA/22-79                    ..REPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.A.R.QVD...GS.PVKPTEPGHADTNNSDN........................
G1P715_MYOLU/283-340                  ..GEPDDAELVKLSKRLVENAVLKAVQQYLEET.QNK.H.K.PGD...GS.TVKTEEADRNGTDNDN-r.......................
A0A091RZL1_NESNO/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A094KEE9_ANTCR/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SSaSLHLERG----------kltkkhekk...............
A0A093PVZ0_9PASS/214-271              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.ETD...GS.PMKTEDAASGSKNESD-k.......................
A0A091HCX3_BUCRH/6-63                 .t-EHDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.KrPNS...GA.SLQLERGNLTKKHE---kk......................
H2PKB8_PONAB/267-324                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
A0A099YYQ9_TINGU/192-249              ..AEPDDAELLSLSKRLVENAVLKAVQQYLEET.QNK.N.K.QAD...GS.PVKTEEAASGSKHENEN........................
F7IC71_CALJA/23-80                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
A0A091KMU0_9GRUI/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNESDN........................
M3YT80_MUSPF/258-315                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.S.K.PGD...GS.SVKTQEAGRNGTESDNN........................
G1KYP3_ANOCA/7-65                     ..AEPDDAELLSLSKRLVENAVLKAVQQYLEET.QNK.N.R.QLD..fGA.PVKTEEPTLG--NNMENgn......................
A0A091HQQ2_CALAN/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN..sGM.SLQLERGKLTKKHE---kk......................
G3HT52_CRIGR/9-57                     .n-EPEEAKLQNASKQIVQNAILRAVQQVSQESlQRG.G.R.PSD...C-.-----------------rprgrlgg................
F6ZQQ8_MACMU/267-324                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
S9WLG8_CAMFR/34-90                    .s-EPEEAKLQSASRQIVQNAILQAVHQVSREA.RRReA.R.TSD...GR.-----------------gsrqpgvgeltkkhe.........
A0A093H3L1_STRCA/6-63                 .p-EQDEVRLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTH...SSmSLQL-------------ergkltkkhekk............
G3RN25_GORGO/10-54                    .n-EPEEVKLQNASKQIVQNAILQAVQQVSQES.QRR.E.E.R--...--.-----------------isdnkdhi................
A0A091TUY1_PHALP/9-66                 .s-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SS.TSHQLER----------gkltkkhekk..............
A0A087R6E3_APTFO/145-202              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTKEAESGSKNESDN........................
A0A087RBG5_APTFO/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTS...SStSLQLER-----------gkltkkhekk..............
H2RG99_PANTR/11-68                    .n-EPEEVKLQNASKQIVQNAILQAVQQVSQES.QRR.E.E.R--...--.-----------------isdnrdhiqlavgeltkknek...
A0A091URR6_NIPNI/192-249              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PMKTEEAASSSKNESDN........................
R7VY68_COLLI/11-68                    .l-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QRK.E.K.RTN...SStSLQLERG----------kltkkhekk...............
A0A091MZZ8_APAVI/6-63                 .l-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RIN...SStSLQLER-----------gkltkkhekk..............
F7IRN7_CALJA/289-346                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
A0A091RTK4_NESNO/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNESDN........................
A0A094NK70_9AVES/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEDAASSSKNESNN........................
K7FYI7_PELSI/258-315                  ..AEPDDAELVNLSKRLVENAVLKAVQQYLEET.QNK.N.R.QAD...GS.PVKTEEAASENKNEND-s.......................
A0A093CME8_TAUER/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RPN..sST.SLQLERGKL--------tkkhekk.................
A0A091S9E8_9GRUI/192-249              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PMKTEEAASGSKNESD-l.......................
G3TSA7_LOXAF/24-81                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGD...GN.SVKPEEADRNV-NDSDNn.......................
AKA7A_MOUSE/22-79                     ..REPEDAELVRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GN.STKAEEGDRNG-DGSDNn.......................
M3ZY69_XIPMA/453-517                  .s-EPDEAELLRVSRRLVEDAVSRALQQYKQETlQNG.G.G.PNAaalQT.PGSTEETKT--------dttansstdnr.............
U3JUZ0_FICAL/11-68                    .t-EQDEIKLQIASKQIVQTAILRAVQQVSQES.QQN.E.K.RTN..tGT.SLQLERGKLTKKHE---kk......................
A0A091R303_MERNU/7-66                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASGSKNA---ggddn...................
G7PWF2_MACFA/10-55                    .n-EPEEVKLQNASKQIVQNAILRAVQQVSQES.QRR.E.E.R--...--.-----------------isdnqghiq...............
G1SA96_NOMLE/10-53                    .n-EPEEVMLQNASKQIVQNAILQAVQQVSQES.QHR.E.E.R--...--.-----------------isdnrdh.................
A0A087VLR4_BALRE/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEEASGSKNESDN........................
G5C774_HETGA/236-293                  ..AEPDDVELVRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GS.SVKAEEADGSG-NGSDNn.......................
F6YG35_HORSE/267-324                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGD...GS.SVKTEEADRNGTDSDNN........................
G1M3N8_AILME/22-79                    ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.S.K.PGD...GS.SVKTQEADRNGTDSDNN........................
Q5RIX0_DANRE/66-114                   sa--PDDEELLSLSKRLVEDAVLRAMQQYMEET.QQNgA.A.HTD...--.-----------------qahsklnst...............
G1T6I1_RABIT/272-329                  ..GEPDDAELLRLSKRLVENAVLKAVQQYLEET.QNK.K.Q.PGE...GS.SVKTGEAERNGNDSDH-n.......................
R4GI69_CHICK/11-68                    .p-EQDEVKLQNASKQIVQTAILQAVQQVSREN.QQK.E.K.RTN...SSmSLQLE------------rgkltkkhekk.............
I3ND12_ICTTR/10-65                    .n-EPEEVKLQNASKQIVQNAILQAVQQVSQES.QPQ.E.D.---...--.-----------------rssdargrsqlgvqeltkkh....
W5P194_SHEEP/6-47                     .s-EPEEAKLQTTSRQIVQNAILRAVQQVSRES.QSR.R.R.DT-...--.-----------------ragd....................
A0A0A0A5C5_CHAVO/6-63                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...SS.TG---------------lqlergkltkkhekk.........
A0A0F8CTS1_LARCR/943-1004             .s-EPDEAELLRVSRRLVEDAVNRALQQYKQETfQNG.G.G.P--...--.-----------------natavqpagstedtatkkdtkans
H3D040_TETNG/254-313                  .s-EPDEAELLRVSRRLVEDAVSRALQQYKQESlQNG.G.G.PQS..pGN.AEETATK----------tgttanstad..............
U3KB21_FICAL/22-79                    ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.S.R.QTD...GS.PAKTEEAASGSKNESDN........................
A0A093QY37_PHACA/7-64                 ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.T.R.QTD...GS.PVKTEEAASSSKNESDN........................
E2RMB3_CANLF/267-324                  ..GEPDDAELLRLSKRLVENAVLKAVQQYLEET.QSR.G.K.PAD...GS.SGKARAADRGGADGDQ-s.......................
A0A0D9RVQ3_CHLSB/289-345              ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNG-NDNEN........................
A0A094KDR0_9AVES/9-66                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTS...SN.-----------------mslqlergkltkkhekk.......
G7P361_MACFA/267-324                  ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
G3UUN3_MELGA/6-63                     .p-EQDEVKLQNASKQIVQTAILQAVQQVSREN.QQK.E.K.RTN...SS.M----------------sfqlergkltkkhekk........
F7IC51_CALJA/45-102                   ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADRNGNDNENN........................
A0A091G8X8_9AVES/215-272              ..AEPDDAELVSLSKRLVENAVLKAVQQYLEET.QNK.P.I.QTD...GS.PMKTEEAANGNKNVSNN........................
AKA7G_HUMAN/289-346                   ..GEPDDAELVRLSKRLVENAVLKAVQQYLEET.QNK.N.K.PGE...GS.SVKTEAADQNGNDNENN........................
#=GR AKA7G_HUMAN/289-346        SS    ..XXX-HHHHHHHHHHHHHHHHHHHHHHHHHHH.HHH.H.X.XXX...XX.XXXXXXXXXXXXXXXXX........................
A0A093Q7A1_9PASS/6-62                 .t-EQDEVKLQNASKQIVQTAILRAVQQVSQES.QQK.E.K.RTN...ST.SLQLERGKLTKKHE---kk......................
#=GC SS_cons                          ..SSSSHHHCCCHHHHHHHHHHHHHHHHHHHHH.HHH.H.X.XXX...XX.XXXXXXXXXXXXXXXXX........................
#=GC seq_cons                         ...EPD-AELlslSKRLVENAVL+AVQQYhcET.QsK.p.+.ps-...GS.slphEput.s..p............................
//
DBGET integrated database retrieval system