GenomeNet

Database: Pfam
Entry: APC2
LinkDB: APC2
Original site: APC2 
#=GF ID   APC2
#=GF AC   PF08672.6
#=GF DE   Anaphase promoting complex (APC) subunit 2
#=GF AU   Mistry J
#=GF SE   pdb_1ldd
#=GF GA   20.30 20.30;
#=GF TC   20.30 20.40;
#=GF NC   20.10 20.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   16481473
#=GF RT   An architectural map of the anaphase-promoting complex. 
#=GF RA   Thornton BR, Ng TM, Matyskiela ME, Carroll CW, Morgan DO,
#=GF RA   Toczyski DP; 
#=GF RL   Genes Dev. 2006;20:449-460.
#=GF DR   INTERPRO; IPR014786;
#=GF DR   SCOP; 1ldd; fa;
#=GF CC   The anaphase promoting complex or cyclosome (APC2) is an E3
#=GF CC   ubiquitin ligase which is part of the SCF family of ubiquitin
#=GF CC   ligases.  Ubiquitin ligases catalyse the transfer of ubiquitin
#=GF CC   from the ubiquitin conjugating enzyme (E2), to the substrate
#=GF CC   protein.
#=GF SQ   240
#=GS B7G3T5_PHATC/703-764    AC B7G3T5.1
#=GS I0Z944_9CHLO/648-707    AC I0Z944.1
#=GS G4MTP9_MAGO7/982-1040   AC G4MTP9.1
#=GS A7EQE3_SCLS1/791-849    AC A7EQE3.1
#=GS F7FLA0_CALJA/759-819    AC F7FLA0.1
#=GS H9G5Y1_ANOCA/713-773    AC H9G5Y1.1
#=GS Q95TK2_DROME/388-447    AC Q95TK2.1
#=GS C6HJI5_AJECH/835-890    AC C6HJI5.1
#=GS A8N071_COPC7/633-688    AC A8N071.2
#=GS B8AVW5_ORYSI/803-862    AC B8AVW5.1
#=GS D4AL15_ARTBC/851-909    AC D4AL15.1
#=GS E1FR62_LOALO/614-672    AC E1FR62.1
#=GS E8PLM9_THESS/3-53       AC E8PLM9.1
#=GS F2QSI9_PICP7/645-704    AC F2QSI9.1
#=GS C7GQC8_YEAS2/784-845    AC C7GQC8.1
#=GS E9CUV8_COCPS/873-931    AC E9CUV8.1
#=GS G9N751_HYPVG/799-857    AC G9N751.1
#=GS G1RCZ5_NOMLE/752-812    AC G1RCZ5.1
#=GS D8QVH1_SELML/664-722    AC D8QVH1.1
#=GS E9FXU1_DAPPU/681-741    AC E9FXU1.1
#=GS A8P5I5_BRUMA/645-703    AC A8P5I5.1
#=GS E7KFJ7_YEASA/599-660    AC E7KFJ7.1
#=GS I1G490_AMPQE/263-319    AC I1G490.1
#=GS B3S490_TRIAD/412-469    AC B3S490.1
#=GS Q0U113_PHANO/763-817    AC Q0U113.2
#=GS G3IG37_CRIGR/204-264    AC G3IG37.1
#=GS A9V8T1_MONBE/763-798    AC A9V8T1.1
#=GS B3MCP3_DROAN/742-801    AC B3MCP3.1
#=GS H8X3G2_9ASCO/740-801    AC H8X3G2.1
#=GS B4I8Y3_DROSE/741-800    AC B4I8Y3.1
#=GS G3RV64_GORGO/768-828    AC G3RV64.1
#=GS C0NCQ8_AJECG/877-935    AC C0NCQ8.1
#=GS B9HI96_POPTR/809-868    AC B9HI96.1
#=GS F6YDG1_CIOIN/522-581    AC F6YDG1.2
#=GS C1GRC2_PARBA/849-907    AC C1GRC2.1
#=GS H6C3B1_EXODN/674-732    AC H6C3B1.1
#=GS C8ZD96_YEAS8/784-845    AC C8ZD96.1
#=GS I1IZ00_BRADI/799-857    AC I1IZ00.1
#=GS B4KLY2_DROMO/732-791    AC B4KLY2.1
#=GS G2WIW6_YEASK/784-845    AC G2WIW6.1
#=GS F8Q0C1_SERL3/691-746    AC F8Q0C1.1
#=GS E0VT63_PEDHC/712-772    AC E0VT63.1
#=GS Q2ULP4_ASPOR/770-828    AC Q2ULP4.1
#=GS C5MHY9_CANTT/737-798    AC C5MHY9.1
#=GS Q3B7T7_RAT/474-534      AC Q3B7T7.1
#=GS A9RVI7_PHYPA/711-769    AC A9RVI7.1
#=GS ANC2_MOUSE/772-832      AC Q8BZQ7.2
#=GS B9S900_RICCO/822-881    AC B9S900.1
#=GS B6K4L3_SCHJY/640-699    AC B6K4L3.1
#=GS D8TUD3_VOLCA/544-593    AC D8TUD3.1
#=GS C5DMX1_LACTC/712-772    AC C5DMX1.1
#=GS A1CEF0_ASPCL/819-877    AC A1CEF0.1
#=GS H0GY87_9SACH/785-805    AC H0GY87.1
#=GS B4QBF9_DROSI/741-800    AC B4QBF9.1
#=GS H0EL14_GLAL7/217-261    AC H0EL14.1
#=GS F0UIN1_AJEC8/878-933    AC F0UIN1.1
#=GS APC2_YEAST/784-845      AC Q12440.1
#=GS APC2_YEAST/784-845      DR PDB; 1LDD A; 784-845;
#=GS APC2_YEAST/784-845      DR PDB; 1LDD D; 784-845;
#=GS APC2_YEAST/784-845      DR PDB; 1LDD B; 784-845;
#=GS APC2_YEAST/784-845      DR PDB; 1LDD C; 784-845;
#=GS A3LQ64_PICST/767-828    AC A3LQ64.2
#=GS A6R253_AJECN/107-165    AC A6R253.1
#=GS E2ACD3_CAMFO/713-773    AC E2ACD3.1
#=GS A7A126_YEAS7/784-845    AC A7A126.1
#=GS I1PME2_ORYGL/805-864    AC I1PME2.1
#=GS G2Y390_BOTF4/843-901    AC G2Y390.1
#=GS F7FZ82_CALJA/757-817    AC F7FZ82.1
#=GS F0XE13_GROCL/948-1006   AC F0XE13.1
#=GS A8I146_CHLRE/446-506    AC A8I146.1
#=GS F2T4A4_AJEDA/884-942    AC F2T4A4.1
#=GS G2QZ10_THITE/992-1050   AC G2QZ10.1
#=GS H0YX17_TAEGU/744-804    AC H0YX17.1
#=GS A2QWI1_ASPNC/887-945    AC A2QWI1.1
#=GS G3W5P1_SARHA/721-781    AC G3W5P1.1
#=GS E7LXL3_YEASV/784-845    AC E7LXL3.1
#=GS F4S940_MELLP/432-489    AC F4S940.1
#=GS F0ZRQ2_DICPU/850-907    AC F0ZRQ2.1
#=GS A6MKD4_CALJA/128-188    AC A6MKD4.1
#=GS B8LYW2_TALSN/853-911    AC B8LYW2.1
#=GS APC2_ARATH/804-863      AC Q8H1U5.1
#=GS Q4WHJ2_ASPFU/834-892    AC Q4WHJ2.1
#=GS D7TN60_VITVI/822-881    AC D7TN60.1
#=GS G8BB86_CANPC/738-799    AC G8BB86.1
#=GS H2AZ81_KAZAF/753-813    AC H2AZ81.1
#=GS C5DY53_ZYGRC/755-816    AC C5DY53.1
#=GS B3NQ41_DROER/741-800    AC B3NQ41.1
#=GS E9C4W2_CAPO3/741-797    AC E9C4W2.1
#=GS D8LNH8_ECTSI/234-294    AC D8LNH8.1
#=GS E9IA33_SOLIN/733-793    AC E9IA33.1
#=GS Q2H5Y0_CHAGB/1055-1113  AC Q2H5Y0.1
#=GS G3JHS1_CORMM/799-857    AC G3JHS1.1
#=GS F8N440_NEUT8/801-860    AC F8N440.1
#=GS F1Q896_DANRE/716-776    AC F1Q896.1
#=GS I1LMG8_SOYBN/823-882    AC I1LMG8.1
#=GS H3IWC6_STRPU/759-819    AC H3IWC6.1
#=GS Q9W1E5_DROME/741-800    AC Q9W1E5.1
#=GS H0VFC1_CAVPO/762-822    AC H0VFC1.1
#=GS G4VSQ4_SCHMA/716-776    AC G4VSQ4.1
#=GS B4J680_DROGR/731-790    AC B4J680.1
#=GS H3GLW2_PHYRM/627-687    AC H3GLW2.1
#=GS Q5BBH1_EMENI/1037-1095  AC Q5BBH1.1
#=GS E1Z3U7_CHLVA/447-505    AC E1Z3U7.1
#=GS E9E620_METAQ/799-857    AC E9E620.1
#=GS I1RBV5_GIBZE/805-863    AC I1RBV5.1
#=GS C5FMT7_ARTOC/1040-1098  AC C5FMT7.1
#=GS H3B1N4_LATCH/758-814    AC H3B1N4.1
#=GS C0S237_PARBP/865-923    AC C0S237.1
#=GS C4JFH7_UNCRE/1043-1101  AC C4JFH7.1
#=GS E5A3L7_LEPMJ/870-926    AC E5A3L7.1
#=GS F1PYP1_CANFA/768-828    AC F1PYP1.1
#=GS H2S6S1_TAKRU/680-740    AC H2S6S1.1
#=GS A5AKI4_VITVI/747-791    AC A5AKI4.1
#=GS B2AUE1_PODAN/1065-1124  AC B2AUE1.1
#=GS F4PGI1_DICFS/762-819    AC F4PGI1.1
#=GS B4IPP1_DROSE/197-256    AC B4IPP1.1
#=GS G8ZXB4_TORDC/745-806    AC G8ZXB4.1
#=GS H2XIK4_CAEJA/136-186    AC H2XIK4.1
#=GS F2RVL9_TRIT1/851-909    AC F2RVL9.1
#=GS Q6P0W7_MOUSE/159-219    AC Q6P0W7.1
#=GS Q17KA5_AEDAE/727-783    AC Q17KA5.1
#=GS G1MDE3_AILME/733-793    AC G1MDE3.1
#=GS E3REK5_PYRTT/870-925    AC E3REK5.1
#=GS H9H0D1_MELGA/719-779    AC H9H0D1.1
#=GS H1V8Q9_COLHI/857-915    AC H1V8Q9.1
#=GS H9J6K5_BOMMO/452-511    AC H9J6K5.1
#=GS G6CYA1_DANPL/690-749    AC G6CYA1.1
#=GS I1MZB3_SOYBN/815-874    AC I1MZB3.1
#=GS D2V3C9_NAEGR/539-599    AC D2V3C9.1
#=GS G5A4Q8_PHYSP/667-727    AC G5A4Q8.1
#=GS A4S4G0_OSTLU/806-864    AC A4S4G0.1
#=GS D5GFB7_TUBMM/506-562    AC D5GFB7.1
#=GS D4D6A4_TRIVH/851-909    AC D4D6A4.1
#=GS C9SJJ2_VERA1/296-354    AC C9SJJ2.1
#=GS D8SAH1_SELML/770-828    AC D8SAH1.1
#=GS B4LP09_DROVI/728-787    AC B4LP09.1
#=GS A6RS02_BOTFB/796-854    AC A6RS02.1
#=GS H0WT36_OTOGA/769-829    AC H0WT36.1
#=GS B5VN58_YEAS6/784-845    AC B5VN58.1
#=GS B8N475_ASPFN/669-727    AC B8N475.1
#=GS G9NHD1_HYPAI/856-914    AC G9NHD1.1
#=GS D7L837_ARALL/805-864    AC D7L837.1
#=GS Q5NRN0_SOLDE/187-246    AC Q5NRN0.2
#=GS Q290C0_DROPS/741-800    AC Q290C0.1
#=GS B3LT88_YEAS1/784-845    AC B3LT88.1
#=GS B9FFT0_ORYSJ/803-862    AC B9FFT0.1
#=GS G0WDF1_NAUDC/848-909    AC G0WDF1.1
#=GS C7YKS1_NECH7/807-865    AC C7YKS1.1
#=GS B4MRL5_DROWI/747-806    AC B4MRL5.1
#=GS Q7XQF0_ORYSJ/859-918    AC Q7XQF0.2
#=GS G3YCZ1_ASPNA/1051-1109  AC G3YCZ1.1
#=GS C4R167_PICPG/645-704    AC C4R167.1
#=GS Q6ZPR8_MOUSE/773-833    AC Q6ZPR8.1
#=GS H3D152_TETNG/691-751    AC H3D152.1
#=GS G1XGF9_ARTOA/969-1026   AC G1XGF9.1
#=GS Q6C6Z8_YARLI/651-710    AC Q6C6Z8.1
#=GS F0YL58_AURAN/624-680    AC F0YL58.1
#=GS Q5C7X6_SCHJA/137-197    AC Q5C7X6.2
#=GS E4UPF8_ARTGP/84-142     AC E4UPF8.1
#=GS A1DFU1_NEOFI/834-892    AC A1DFU1.1
#=GS G0RZK6_CHATD/1015-1073  AC G0RZK6.1
#=GS E3X2S9_ANODA/721-777    AC E3X2S9.1
#=GS G8BR63_TETPH/780-840    AC G8BR63.1
#=GS B4PAB8_DROYA/741-800    AC B4PAB8.1
#=GS APC2_SCHPO/621-680      AC Q874R3.1
#=GS G2Q3S0_THIHA/1093-1151  AC G2Q3S0.1
#=GS G3PQ09_GASAC/704-764    AC G3PQ09.1
#=GS E3QEJ3_COLGM/861-919    AC E3QEJ3.1
#=GS G3SUH0_LOXAF/769-829    AC G3SUH0.1
#=GS B8JLK0_DANRE/737-797    AC B8JLK0.1
#=GS B8PA13_POSPM/669-724    AC B8PA13.1
#=GS Q7SE61_NEUCR/806-865    AC Q7SE61.2
#=GS E9EV64_METAR/799-857    AC E9EV64.1
#=GS C3YTV7_BRAFL/755-814    AC C3YTV7.1
#=GS F2SJX4_TRIRC/849-907    AC F2SJX4.1
#=GS G7KTW0_MEDTR/848-907    AC G7KTW0.1
#=GS H3EH95_PRIPA/29-89      AC H3EH95.1
#=GS H2WCH6_CAEJA/772-822    AC H2WCH6.1
#=GS Q01IF9_ORYSA/803-862    AC Q01IF9.1
#=GS B6HUV4_PENCW/855-913    AC B6HUV4.1
#=GS B2W8F0_PYRTR/883-937    AC B2W8F0.1
#=GS F6XXR8_MONDO/774-834    AC F6XXR8.1
#=GS F7DMN6_XENTR/755-815    AC F7DMN6.1
#=GS D0N4D6_PHYIT/666-726    AC D0N4D6.1
#=GS G7XA65_ASPKW/885-943    AC G7XA65.1
#=GS APC2_DICDI/848-905      AC Q551S9.1
#=GS C5PHE4_COCP7/873-931    AC C5PHE4.1
#=GS C1FJA1_MICSR/815-873    AC C1FJA1.1
#=GS G0RCM1_HYPJQ/819-877    AC G0RCM1.1
#=GS Q5ADM0_CANAL/744-805    AC Q5ADM0.1
#=GS G7YX14_CLOSI/805-865    AC G7YX14.1
#=GS A7STC1_NEMVE/511-571    AC A7STC1.1
#=GS B0WAC8_CULQU/723-779    AC B0WAC8.1
#=GS B4GCG5_DROPE/741-800    AC B4GCG5.1
#=GS Q0CK13_ASPTN/1182-1240  AC Q0CK13.1
#=GS F2PNL4_TRIEC/851-909    AC F2PNL4.1
#=GS G5BZF9_HETGA/608-668    AC G5BZF9.1
#=GS E7KRP6_YEASL/784-845    AC E7KRP6.1
#=GS H2L6C9_ORYLA/738-798    AC H2L6C9.1
#=GS F7VL53_SORMK/1052-1111  AC F7VL53.1
#=GS Q3U430_MOUSE/768-828    AC Q3U430.1
#=GS H0GK84_9SACH/784-845    AC H0GK84.1
#=GS H9KCF0_APIME/533-593    AC H9KCF0.1
#=GS B6Q3P3_PENMQ/1022-1080  AC B6Q3P3.1
#=GS G7DVC9_MIXOS/677-734    AC G7DVC9.1
#=GS B9WER1_CANDC/739-800    AC B9WER1.1
#=GS Q7Q9T8_ANOGA/724-780    AC Q7Q9T8.4
#=GS Q5SCA3_OSTTA/792-850    AC Q5SCA3.1
#=GS F7FKQ0_CALJA/758-818    AC F7FKQ0.1
#=GS H2PU30_PONAB/757-817    AC H2PU30.1
#=GS Q0JC96_ORYSJ/803-862    AC Q0JC96.2
#=GS G3R7Q5_GORGO/757-817    AC G3R7Q5.1
#=GS Q6F2D1_SOLDE/823-882    AC Q6F2D1.1
#=GS C5GEY3_AJEDR/884-942    AC C5GEY3.1
#=GS B8C5R7_THAPS/697-758    AC B8C5R7.1
#=GS F7G3J3_MACMU/757-817    AC F7G3J3.1
#=GS G0VCV7_NAUCC/749-810    AC G0VCV7.1
#=GS F4WZV1_ACREC/712-772    AC F4WZV1.1
#=GS E2C9F0_HARSA/646-706    AC E2C9F0.1
#=GS I1EG36_AMPQE/138-175    AC I1EG36.1
#=GS G7JGA9_MEDTR/149-208    AC G7JGA9.1
#=GS ANC2_HUMAN/757-817      AC Q9UJX6.1
#=GS E4XA84_OIKDI/614-673    AC E4XA84.1
#=GS G7JG99_MEDTR/830-889    AC G7JG99.1
#=GS F1NLT0_CHICK/755-815    AC F1NLT0.1
#=GS D6WHQ9_TRICA/698-757    AC D6WHQ9.1
#=GS D3BDT3_POLPA/709-766    AC D3BDT3.1
#=GS G4U6F7_NEUT9/806-865    AC G4U6F7.1
#=GS E7QHY1_YEASZ/784-845    AC E7QHY1.1
#=GS Q6FJR3_CANGA/718-779    AC Q6FJR3.1
#=GS F9FM66_FUSOF/806-864    AC F9FM66.1
#=GS C4WTA5_ACYPI/44-103     AC C4WTA5.1
#=GS F1KZ77_ASCSU/674-732    AC F1KZ77.1
#=GS F8P069_SERL9/685-740    AC F8P069.1
#=GS B2RYJ1_RAT/771-831      AC B2RYJ1.1
#=GS C5JT88_AJEDS/884-942    AC C5JT88.1
#=GS C1N0W3_MICPC/587-645    AC C1N0W3.1
#=GS C1G921_PARBD/865-923    AC C1G921.1
#=GS B0XVH2_ASPFC/834-892    AC B0XVH2.1
#=GS H2ZEA6_CIOSA/122-181    AC H2ZEA6.1
#=GS H2QY82_PANTR/704-761    AC H2QY82.1
#=GS G3N1P9_BOVIN/156-216    AC G3N1P9.1
#=GS H9I127_ATTCE/759-819    AC H9I127.1
#=GS C8VLZ0_EMENI/858-916    AC C8VLZ0.1
B7G3T5_PHATC/703-764               ...............YVVGMLT.NLGQ..LPLKTIHNNLKTF.VTGSdVRYDKTPQQLSAFLQNLCRQERLECGpDGMYKL........
I0Z944_9CHLO/648-707               ...............FVMGMLT.NFDG.gLALDRIHNMLKMF.-VVD.PPYDKSAEQLATFLGQLVADEKLSCE.AGVFR-k.......
G4MTP9_MAGO7/982-1040              ...............FIVGMLT.NSAA.sMPLAQISMMMKMM.--MA.GGFPWSNEELQEFLAQKVAEGQMEVV.GGKYKL........
A7EQE3_SCLS1/791-849               ...............FVQSMLT.NSSS.rMGAPQIAMMLKML.--IA.EGFPYSNEELLEWLGGKVEEGVLECV.GGRYKL........
F7FLA0_CALJA/759-819               ...............YIQAMLT.NLES..LSLERIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
H9G5Y1_ANOCA/713-773               ...............YIQAMLT.NLES..LSLERIHSMLKLFvMTGP.MVTEPDLQELQGFLQKKVRDQQLTYT.GGVYRL........
Q95TK2_DROME/388-447               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
C6HJI5_AJECH/835-890               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFGSEELREFLSQMVAKGRLEVS.------prnl....
A8N071_COPC7/633-688               ...............FIEGMLK.NLGS..LPLDRIQTMLRLA.----.PGYDQTIEQLGMFMEAARREGMVTSR.------dgmwrl..
B8AVW5_ORYSI/803-862               ...............FIIGMLT.NFGS..MTLDRIHNTLKMF.CIAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGSYL-l.......
D4AL15_ARTBC/851-909               ...............FIKGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGELEMVsGGNYKI........
E1FR62_LOALO/614-672               ...............YTKSFIA.NQEP..VKAERLHTIFRMF.-ASP.GQHGPTLEDVVAFLQRKVKMNLLSCV.NGLYK-v.......
E8PLM9_THESS/3-53                  avealrfatfkeiqr-------.----..-----------YL.--DE.EGEAFSKKELEDTLTSLVAEGRLEEK.EGTYRL........
F2QSI9_PICP7/645-704               ...............FIVGMLT.NLGP..TALSQMHSFLKML.VPQE.TPYNATEKQLELYLHSCIEEEKLEVN.GDKYKL........
C7GQC8_YEAS2/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
E9CUV8_COCPS/873-931               ...............FIVGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPYSSEELREFLGKMVAKGKLEMIgGGNYKI........
G9N751_HYPVG/799-857               ...............FIVGMLT.NSSP.aMPLGQIAMMMKML.--LS.DGCPWSNEELQEFLGEKITEGELELV.GGKYRL........
G1RCZ5_NOMLE/752-812               ...............YIQAMLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
D8QVH1_SELML/664-722               ...............YIVGMLT.NLES..LPLDRIHNMLKMF.-VSD.PPYDKTLQQLQGFLGSLIADEKLEFR.EGVYR-r.......
E9FXU1_DAPPU/681-741               ...............YVVGMLT.NLEA..LPVERIHQMLKMFtMQGS.SGAECTLQQLKNFLDSKVKQQLLSFS.SGMYRL........
A8P5I5_BRUMA/645-703               ...............YTKSFIA.NQEP..VKAERLHTIFRMF.-ASP.GQHGPTLEDVVAFLQRKVKLNLLSCV.NGLYK-v.......
E7KFJ7_YEASA/599-660               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
I1G490_AMPQE/263-319               ...............YVTAMLT.NLGP..MSLDKIHNMLRPGgGGGA.GQSSCTVAELKACLDKKSSNKK----.------rpftin..
B3S490_TRIAD/412-469               ...............YIVGMLT.NFPA..MELDRICSSLKLF.--IP.SAGELSSRDLKMFLDKKVQEQKLTHN.NGEYAL........
Q0U113_PHANO/763-817               ...............FILGMLT.NQGN..MPVPRILMMMRMM.--VQ.GGFPFGAEEVREVLAEMEGGG-----.------kvvgfggd
G3IG37_CRIGR/204-264               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
A9V8T1_MONBE/763-798               ...............FVEGMLR.NAAS..LPLERIHVMLSMF.MQGD.QAFN----------------------.------gdvk....
B3MCP3_DROAN/742-801               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
H8X3G2_9ASCO/740-801               ...............YVVRMLS.NITA..LNFERMKSLLKMMvPKDEiDVSTMDETLLKSYLDHLVEIAKINCT.DGNYSL........
B4I8Y3_DROSE/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
G3RV64_GORGO/768-828               ...............YIQAMLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
C0NCQ8_AJECG/877-935               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFGSEELREFLSQMVAKGRLEVVsGGSYKI........
B9HI96_POPTR/809-868               ...............FIMGMLT.NFGS..MALDRIHNTLKMF.CVAD.PPYDKSLQQLQSFLSGLVSEEKLELR.DGMY--fl......
F6YDG1_CIOIN/522-581               ...............YIKGMLK.NFQS..LPIDRIHKMLKMF.AVND.ANMQIELPQLKQILNEKVQQGLLVLN.GGKFKL........
C1GRC2_PARBA/849-907               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFSSEELRAFLSQMVSKGKLEVVsGGSYKI........
H6C3B1_EXODN/674-732               ...............FIVSMLT.NQGA..MPLPRIAMMLGIV.--VP.GGFPFSNEELKEFLAGMIKDGVLEVGhGGAYR-v.......
C8ZD96_YEAS8/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
I1IZ00_BRADI/799-857               ...............FIIGMLT.NFGN..MTLDKIHNTLKMF.-CAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGLYL-l.......
B4KLY2_DROMO/732-791               ...............YIVGMLT.NLDC..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLLFS.GGVYQL........
G2WIW6_YEASK/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLERYLNTLADEGRLKYIaNGSYEI........
F8Q0C1_SERL3/691-746               ...............FIEGMLT.NLGS..LSLDRIQTMLKFA.----.PGYDRTIDQLGSFMEGAKREGLVTFK.DGMWKL........
E0VT63_PEDHC/712-772               ...............YIVGMLT.NLES..MPLERIHQMLKMFaSQGT.SAVDCSQKELGVFLDRKVREHKLLFS.GGLYRL........
Q2ULP4_ASPOR/770-828               ...............FIMGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVAKGKLEIVsGGNYKI........
C5MHY9_CANTT/737-798               ...............YLLTMLQ.NITS..LSFQRIKTLLNLMvPKDKlNLTKITDSLLEEYLDSLVEDSKLHIR.HGNYSL........
Q3B7T7_RAT/474-534                 ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
A9RVI7_PHYPA/711-769               ...............YVIGMLT.NFDS..LPLDRIHNMLKMF.-VSD.PPYDKTLQQLQGFLGRLVGEEKLEFR.EGVYR-r.......
ANC2_MOUSE/772-832                 ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
B9S900_RICCO/822-881               ...............FIMGMLT.NFGS..MALDRIHNTLKMF.CVAD.PPYDKSLQQLQSFLSGLVSEEKLELR.DGMYL-l.......
B6K4L3_SCHJY/640-699               ...............FVVGMLT.NLGA..LELERIHNMLTMF.VPPP.NGYTRSQAELREFLALMIKEEKLEFT.GGAYKL........
D8TUD3_VOLCA/544-593               ...............YIKGMLQ.NYGG..LPLDRLNHMLRLF.VVST.PKYDKTPEQLQVWHPTLVNE------.------ah......
C5DMX1_LACTC/712-772               ...............FIKGMLT.NLGS..LKADKIHSFLKMA.VPKE.IGYSATPSQLQLYLNALVEESKLVKTpNGAFRL........
A1CEF0_ASPCL/819-877               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVAKGQLEIIsGGSYKI........
H0GY87_9SACH/785-805               ...............FIEGMLA.NLGA..MKLNKIHSFL---.----.--------------------------.------........
B4QBF9_DROSI/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
H0EL14_GLAL7/217-261               ...............FIQGMLK.NSSS.qMPLQQISMMLKIC.--GD.RLFMCPPEIL----------------.------knsfetev
F0UIN1_AJEC8/878-933               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFGSEELREFLSQMVAKGRLEVS.------prnl....
APC2_YEAST/784-845                 ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
#=GR APC2_YEAST/784-845      SS    ...............HHHHHHH.HH-S..EEHHHHHHHHHHHS-GGG.--TT--HHHHHHHHHHHHHTTSEE--TTTEEEE........
A3LQ64_PICST/767-828               ...............YLKSMLE.NISY..LKFERVKTLLKLTvPKDKfDFGTIDDSKLEDYLDWLVDEEKLEIT.QQSYKL........
A6R253_AJECN/107-165               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFGSEELREFLSQMVAKGRLEVVsGGSYKI........
E2ACD3_CAMFO/713-773               ...............YIVGMLT.NLDS..MPIERIHQMLKMFaSQGP.GAVECGLPELRQFLDRKVREHQLLLS.GSFYRL........
A7A126_YEAS7/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
I1PME2_ORYGL/805-864               ...............FIIGMLT.NFGS..MTLDRIHNTLKMF.CIAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGSYL-l.......
G2Y390_BOTF4/843-901               ...............FVQSMLT.NSSS.qMGAPQIAMMLKML.--IA.EGFPYSNEELLEWLGGKVEEGVLECV.GGRYRL........
F7FZ82_CALJA/757-817               ...............YIQAMLT.NLES..LSLERIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
F0XE13_GROCL/948-1006              ...............FIVGMLT.NSAA.sMPLAQIAMMMKML.--MA.EGFPWSNEELLEFLGEKVMDGELEVI.GGKYRL........
A8I146_CHLRE/446-506               ..............l--VGMVTqNYGG..LPLERLNHMLRLF.VVST.PRYDKTPEQLQAFLQVLIAREVVVLEsNGVYK-w.......
F2T4A4_AJEDA/884-942               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFSSEELRGFLSQMVAKGKLEVVsGGSYKI........
G2QZ10_THITE/992-1050              ...............YIQGMLT.NASA.sMPLGQMAMMMRML.--IA.DGFPWSNEELQEFLAEKVAAGEMEVV.GGKYRL........
H0YX17_TAEGU/744-804               ...............YIQAMLT.NLES..LSLERIHSMLKMFvMTGP.VVTEIDIQELQGFLQKKVRDQQLIYS.GGVYRL........
A2QWI1_ASPNC/887-945               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPYSNEELREFLAGMVSKGKLEIIsGGNYKI........
G3W5P1_SARHA/721-781               ...............YIQAMLT.NLES..LSLERIHSMLKMFvMTGP.VVTEIDLQELQGFLQKKVRDQQLIYS.GGVYRL........
E7LXL3_YEASV/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
F4S940_MELLP/432-489               ...............FIVGMLT.NLGG..LPLERIFVTLNTV.--MP.TFKGTTRDELSSLLEMMQREGTVIP-.------mgdlwki.
F0ZRQ2_DICPU/850-907               ...............FIIGMLM.NFKA..LPLERIHAMLTMF.--NS.EQYTSTIQELKVFLSKLQNEEKIELV.GNDYKI........
A6MKD4_CALJA/128-188               ...............YIQAMLT.NLES..LSLERIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
B8LYW2_TALSN/853-911               ...............FIVGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSNEELREFLASMVAQGKLEVVsGGSYKI........
APC2_ARATH/804-863                 ...............FIMGMLT.NFGS..MALERIHNTLKMF.CVAD.PSYDKSLQQLQSFLSGLVSEEKLEFR.DGMYL-l.......
Q4WHJ2_ASPFU/834-892               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVAKGKLEIIsGGNYKL........
D7TN60_VITVI/822-881               ...............FIMGMLT.NFGS..MALDRIHNTLKMF.CLAD.PPYDKSLQQLQSFLSGLVSEEKLEIR.DGMY--fl......
G8BB86_CANPC/738-799               ...............YVMRMLS.NITA..LNYDRVKSLLKMMvPKDEiDVTTVEDALLQSYLDHLVSSGRINFT.EGNYSL........
H2AZ81_KAZAF/753-813               ...............YIKTMLE.SFGN..LSASRIQNFLKAT.LPAA.QDSDHIITDIHSVLDTLVSDGILFKNsSGSYKL........
C5DY53_ZYGRC/755-816               ...............FIQGMLT.NLGA..LKVKKIHSFLKVTtPKEL.GFSMVTPSQLESYLHSLVEEERLICTtNDTYKL........
B3NQ41_DROER/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
E9C4W2_CAPO3/741-797               ...............FVSMMLT.NLGS..LPADRMLTMMGMY.---A.PTMPIDDRSFRRFLSNMVADGKLATS.GGEYQL........
D8LNH8_ECTSI/234-294               ...............FLTGMLT.NFSK..LPLDRIHNNLKMFmSGGD.NKYDKSLPELQQLLWRLCSDGKLEHA.DGEYRL........
E9IA33_SOLIN/733-793               ...............YIVGMLT.NLDS..LPIERIHQMLKMFaSQGP.GAVECGLPELRQFLDKKVREHQLLLS.GSYYRL........
Q2H5Y0_CHAGB/1055-1113             ...............YIQGMLT.NAST.sMPLAQMAMMMKVL.--IA.DGFPWSNEELQDFLGEKVAGGEMEVV.GGKYRL........
G3JHS1_CORMM/799-857               ...............FILGMLT.NSAP.aMPLSQIAMMMKML.--IA.DGCHWSTEELQEFLEERIMAGELELA.GGKYRL........
F8N440_NEUT8/801-860               ...............YIKGMLT.NAST.sMPLAQMAMMMKML.--IA.DGFPWTNEELGEFLAEKIAEGEMELVsGGKYRL........
F1Q896_DANRE/716-776               ...............YIQAMLT.NLES..MTLERIHSMLRMFvAAGP.GVTEMDVNELQAFLQKKVRAHQLTVS.TGVYRL........
I1LMG8_SOYBN/823-882               ...............FILGMLT.NFGS..MALDRIHNTLKMF.CIAD.PPYDKSLQQLQSFLSGLVSEEKLELR.DGMY--fl......
H3IWC6_STRPU/759-819               ...............FITGMLM.NLES..LPLERIHSMLKMFaIQGP.STTEFTENELRHLLETKVREQQLVYS.AGTYRL........
Q9W1E5_DROME/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
H0VFC1_CAVPO/762-822               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
G4VSQ4_SCHMA/716-776               ...............YITAMLT.NLGS..SSLDRIHSMLRMFaLGST.SSLGFNRDELRRFLDKKIREGQLSYD.GDMYKL........
B4J680_DROGR/731-790               ...............YIVGMLT.NLDC..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLLFS.GGVYQL........
H3GLW2_PHYRM/627-687               ...............YIVGMLS.NFGS..LTIHRIHNMLSTFaRSGA.QPYTKTISGLSVVLGKLVDKGKLELV.GGQYQL........
Q5BBH1_EMENI/1037-1095             ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVSKGKIEIVsGGNYKI........
E1Z3U7_CHLVA/447-505               ...............FIMGMLT.NFDA..LPLDRVHNMLKMF.-VSD.PPYDKTLEQLGAYMGRLVADEKLSLD.GGTYR-k.......
E9E620_METAQ/799-857               ...............FIVGMLT.NSSP.aMPLGQIAMMMKML.--IA.DGCPWNNEELQEFLGEKIAEGELELS.GGKYRL........
I1RBV5_GIBZE/805-863               ...............FIVGMLT.NSAP.tMPLAQMLMMMKML.--IP.DGCPWTNEELQEFLAEKVAENKLELA.GGKYRL........
C5FMT7_ARTOC/1040-1098             ...............FIKGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGELEMVsGGNYKI........
H3B1N4_LATCH/758-814               ...............YIQAMLT.NLES..LSLERIHSMLKMF.---V.MTGPIDIQELQSFLQKKVLDQQLVCF.GGVYRL........
C0S237_PARBP/865-923               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFSSEELRAFLSQMVSKGKLEVVsGGSYKI........
C4JFH7_UNCRE/1043-1101             ...............FIVGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKEFLGKMVAKGKLEMLgGGNYKI........
E5A3L7_LEPMJ/870-926               ...............FILGMLT.NQGD..LSTQRIALMMRMM.--VQ.GGFPFGEDEVEGLLGGLEEGGRVVGV.G-----ggvw....
F1PYP1_CANFA/768-828               ...............YIQAMLT.NLES..LSLERIYSMLRMFvVTGP.ALAEIDLQELQGFLQKKVRDQQLVYS.AGVYRL........
H2S6S1_TAKRU/680-740               ...............YIQAMLT.NLDS..MTLDRIHSMLRMFvATGP.VVTEMDVNELEAFLQRKVREHQLMVS.AGVYRL........
A5AKI4_VITVI/747-791               ........kemivye-------.----..-----------MF.CLAD.PPYDKSLQQLQSFLSGLVSEEKLEIR.DGMY--fl......
B2AUE1_PODAN/1065-1124             ...............YIQGMLT.NSSV.tMPINQIAMMMGVF.--VI.GGFSWSHEELQSFLGEKVEEGALEVVsGGKYKL........
F4PGI1_DICFS/762-819               ...............FVIGMLT.NFKS..MPIDRMHNMLTMF.--NP.DVYTSSMTDLKQFLTRLQNQDKIELS.SGEYKI........
B4IPP1_DROSE/197-256               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLIFS.GGVYQL........
G8ZXB4_TORDC/745-806               ...............FVQGMLT.NLGS..LKAAKIHSFLKVTvPKEV.GYIVVTQSQLESYLNSLVEEERLACTtSGSYKL........
H2XIK4_CAEJA/136-186               ............nge-------.----..VKAERMHRVYRMF.-GSP.TSAGPTLDHVSQFLQRKVALGLLTCI.NGSYRI........
F2RVL9_TRIT1/851-909               ...............FIKGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGELEMVsGGNYKI........
Q6P0W7_MOUSE/159-219               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
Q17KA5_AEDAE/727-783               ...............YIEAMLT.NLDS..LPLERIHQMLKMF.---A.SQVEFTPEELKNILQRKVREHKLVYV.SGVYQL........
G1MDE3_AILME/733-793               ...............YIQAMLT.NLES..LSLERIYSMLRMFvVTGP.ALAEIDLQELQGFLQKKVRDQQLVYA.AGVYRL........
E3REK5_PYRTT/870-925               ...............FILGMLT.NQGN..MNLPRIFMMMRLM.--VQ.GGFPFAEDDVGALLVELEEGGKVVKV.GG----dv......
H9H0D1_MELGA/719-779               ...............YIQAMLT.NLES..LSLERIHSMLKMFvMTGP.VVTEIDIQELQGFLQKKVRDQQLIYS.GGVYRL........
H1V8Q9_COLHI/857-915               ...............FIVGMLT.NSSP.aMPLGQIAMMMKML.--IA.DGFPWSNEELQEFLAEKMAEEELELA.GGKYRL........
H9J6K5_BOMMO/452-511               ...............YIVGMLT.NLDC..LPLDRIHQMLKMF.ASQA.PGTECSLMELRQFLDTKVRTHQLVLQ.GGMYKL........
G6CYA1_DANPL/690-749               ...............YIVGMLT.NLDS..LPLERIHQMLKMF.ASQA.PGTECSLQELRQFLDTKVRTHQLILQ.AGMYKL........
I1MZB3_SOYBN/815-874               ...............FILGMLT.NFGS..MALDRIHNTLKVF.CIAD.PPYDKSLQQLQSFLSGLVSEEKLELR.DGMY--fl......
D2V3C9_NAEGR/539-599               ..............i-IINMIE.NFDS..MPLAKIHNMLAMF.ALDPlPPFDKSLSELSSFLNILVKEEVLECD.GGEYKI........
G5A4Q8_PHYSP/667-727               ...............YIVGMLS.NFGS..LTIQRIHNMLSTFaRSGA.QPYTKTISGLSVVLGKLVDKGKLELV.GGQYQL........
A4S4G0_OSTLU/806-864               ...............YIMGMLT.NFPS..LPLDRIHNMLKMF.-VVE.PVYDKTVAELEGFLLELVAQDKLAMD.GSAFA-k.......
D5GFB7_TUBMM/506-562               ...............FVVGMLT.NGGA..MPLERISVMLGLV.---P.GGFSWGQEELREFLSRMKSEGKVEYE.GGSWRI........
D4D6A4_TRIVH/851-909               ...............FIKGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGELEMVsGGNYKI........
C9SJJ2_VERA1/296-354               ...............FIFGMLT.NSAP.tMPLGQMAMMMKML.--IP.DGFPWSNEELQEFLAEKMAEGELELV.GGKYRL........
D8SAH1_SELML/770-828               ...............YIVGMLT.NLES..LPLDRIHNMLKMF.-VSD.PPYDKTLQQLQGFLGSLIADEKLEFR.EGVYR-r.......
B4LP09_DROVI/728-787               ...............YIVGMLT.NLDC..MPIDRIHQMLKLF.ASHS.GGVEFTQEELKHFLQRKVREHKLLFS.GGVYQL........
A6RS02_BOTFB/796-854               ...............FVQSMLT.NSSS.qMGAPQIAMMLKML.--IA.EGFPYSNEELLEWLGGKVEEGVLECV.GGRYRL........
H0WT36_OTOGA/769-829               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLHELQGYLQKKVRDQQLIYS.AGVYRL........
B5VN58_YEAS6/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
B8N475_ASPFN/669-727               ...............FIMGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVAKGKLEIVsGGNYKI........
G9NHD1_HYPAI/856-914               ...............FIVGMLT.NSSP.aMPLGQIAMMMKML.--IA.DGCPWSNEELQEFLAEKIAEGELEIV.GGKYRL........
D7L837_ARALL/805-864               ...............FIMGMLT.NFGS..MALERIHNTLKMF.CVAD.PSYDKSLQQLQSFLSGLVSEEKLEFR.DGMYL-l.......
Q5NRN0_SOLDE/187-246               ...............FITGMLT.NFGS..MALDRIHNTLKMF.CIAD.PTYDKSLQQLQSFLSGLVAEEKLEFR.DGMY--fl......
Q290C0_DROPS/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLLFS.GGVYQL........
B3LT88_YEAS1/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
B9FFT0_ORYSJ/803-862               ...............FIIGMLT.NFGS..MTLDRIHNTLKMF.CIAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGSYL-l.......
G0WDF1_NAUDC/848-909               ...............FINGMLE.NLGS..MKLEKIHSFLKMTvPRDF.EYNRIAIHQLENYLNGLVEDEKLETTtDGAFK-k.......
C7YKS1_NECH7/807-865               ...............FIVGMLT.NSAP.aMPLAQILMMMKML.--IA.DGCTWSNEELQEFLGEKVAENELELA.GGKYRL........
B4MRL5_DROWI/747-806               ...............YIVGMLT.NLDS..MPIDRIHQMLRLF.ASHS.GGVEFTQDELKHFLQRKVREHKLLFS.GGVYQL........
Q7XQF0_ORYSJ/859-918               ...............FIIGMLT.NFGS..MTLDRIHNTLKMF.CIAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGSYL-l.......
G3YCZ1_ASPNA/1051-1109             ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPYSNEELREFLAGMVSKGKLEIIsGGNYKI........
C4R167_PICPG/645-704               ...............FIVGMLT.NLGP..TALSQMHSFLKML.VPQE.TPYNATEKQLELYLHSCIEEEKLEVN.GDKYKL........
Q6ZPR8_MOUSE/773-833               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
H3D152_TETNG/691-751               ...............YIQAMLT.NLDS..MTLDRIHSMLRMFvATGP.VVTEMDVNELEAFLQRKVREHQLMVS.AGVYRL........
G1XGF9_ARTOA/969-1026              ...............YIAGMLT.NQGP..LTTDRVFATLSLF.LIPM.GGLKFDAAELDHFMMKMEENGRV---.------dktpsgw.
Q6C6Z8_YARLI/651-710               ...............YIHAMLT.NRGS..LPVIQMHSFLKML.VPKE.TPYTATQDELKQFLQAMVDEEKLDVV.GAKFKL........
F0YL58_AURAN/624-680               ...............YILGLLT.NLGL..LPFLRIHDLLRVL.MSR-.--DNISSRRLSRVLEQMCIRHEIEYS.RGLYKL........
Q5C7X6_SCHJA/137-197               ...............YITAMLT.NLGS..LSLDRIHSMLRMFaLGST.SGLEFSKDELRRFLDRKIREGQLGCD.GDVYKL........
E4UPF8_ARTGP/84-142                ...............FIKGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGDLEMVsGGNYKI........
A1DFU1_NEOFI/834-892               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVAKGKLEIIsGGNYKI........
G0RZK6_CHATD/1015-1073             ...............YVQGMLT.NASA.tMPLAQIAMMLRML.--IA.DGFPWSNEELGDFLSEKVSEGLLEIV.GGKYRL........
E3X2S9_ANODA/721-777               ...............YIEAMLT.NLDS..LPLDRIHQMLKMF.---A.SQVDFTQDELKNILQKKVREHKLVYA.GGVYQL........
G8BR63_TETPH/780-840               ...............YVLSILT.NLGE..QNIEKLYNVLQTT.SHDT.AIKKVSSVTLENIVTELVENGQILCLpNGLYQL........
B4PAB8_DROYA/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQEELKHFLQRKVREHKLIFS.GGVYQL........
APC2_SCHPO/621-680                 ...............FVVGMLT.NLGA..LELERIHNMLTMF.IPPP.NGYTRTQSELREFLALMIKEEKLEFT.GGAYKL........
G2Q3S0_THIHA/1093-1151             ...............YIQGMLT.NASA.tMPLTQMAMMMRML.--IT.DGFPWSDEELQDFLAEKVAEGLMELV.GGKYRL........
G3PQ09_GASAC/704-764               ...............YIQAMLT.NLDS..MTLDRIHSMLRMFvATGP.VVTEMDVNELEAFLQRKVREHQLMVS.AGVYRL........
E3QEJ3_COLGM/861-919               ...............FIVGMLT.NSSP.aMPLGQIAMMMKML.--IA.DGFPWSNEELQEFLAEKMAEEELELV.GGKYRL........
G3SUH0_LOXAF/769-829               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQSYLQKKVRDHQLIYS.AGVYRL........
B8JLK0_DANRE/737-797               ...............YIQAMLT.NLES..MTLERIHSMLRMFvAAGP.GVTEMDVNELQAFLQKKVRAHQLTVS.TGVYRL........
B8PA13_POSPM/669-724               ...............FIEGMLT.NLGT..LSLDRIQTMLKFA.----.PGYDRTIEQLGTFMEAARREGLVNVK.DGMWKL........
Q7SE61_NEUCR/806-865               ...............YIKGMLT.NASA.sMPLAQMAMMMKML.--IA.DGFPWTNEELGEFLAEKIAEGEMELVsGGKYRL........
E9EV64_METAR/799-857               ...............FIVGMLT.NSSP.aMPLGQIAMMMKML.--IA.DGCPWNNEELQEFLGEKIAEGELELS.GGKYRL........
C3YTV7_BRAFL/755-814               ...............YVQGMLT.NLDS..LPLERIHSMLKMF.AMRD.NPIEISLQELKAFLDSKVRSQQLLLS.GGKYKL........
F2SJX4_TRIRC/849-907               ...............FIKGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGELEMVsGGNYKI........
G7KTW0_MEDTR/848-907               ...............FILGMLT.NLGS..MTLDRIHNMLKMV.CIAD.PPYDKSLQQLQSFLSGLVSEEKLKFR.DGTYI-l.......
H3EH95_PRIPA/29-89                 .............yt--KSFIA.NQEAgeVKAERMLNIYRMF.-QSP.SSQQISMDTVVAFLSRKVKLGLLTMN.NGMYK-v.......
H2WCH6_CAEJA/772-822               ............nge-------.----..VKAERMHRVYRMF.-GSP.TSAGPTLDHVSQFLQRKVALGLLTCI.NGSYRI........
Q01IF9_ORYSA/803-862               ...............FIIGMLT.NFGS..MTLDRIHNTLKMF.CIAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGSYL-l.......
B6HUV4_PENCW/855-913               ...............FIVGMLT.NQGP..MALNRIVMMLKIA.--VP.GGFPFSNEELREFLGGMVSKGKLEIVnGGNYKI........
B2W8F0_PYRTR/883-937               ...............FIIGMLT.NQGN..MNTGRIAMMMRLM.--VQ.GGFPGGEAEVRGLLAELEDGGRVVKV.GG----d.......
F6XXR8_MONDO/774-834               ...............YIQAMLT.NLES..LSLERIHSMLKMFvMTGP.VVTEIDLQELQGFLQKKVRDQQLIYS.GGVYRL........
F7DMN6_XENTR/755-815               ...............YIQAMLT.NLES..LPLERIHTMLKMFvMTGP.VVTEIDIQELQSFLQKKVSDHQLVYS.GGVYRL........
D0N4D6_PHYIT/666-726               ...............YIVGMLS.NFGS..LSIQRIHNMLSTFaRSGA.QPYTKTISGLSVVLGKLVNTNKLEFV.GGQYQL........
G7XA65_ASPKW/885-943               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPYSNEELREFLAGMVSKGKLEIIsGGSYKI........
APC2_DICDI/848-905                 ...............FIIGMLI.NFKT..LPLERIHSMLTMF.--NS.ELYTSTIHELKAFLSKLVNEEKIELV.GNDFKI........
C5PHE4_COCP7/873-931               ...............FIVGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPYSSEELREFLGKMVAKGKLEMIgGGNYKI........
C1FJA1_MICSR/815-873               ...............YVIGMLT.NFPS..LPPDRIHNMLKMF.-VQD.PPYDRSLDQLEAFLGQLVAEDKLALE.GNQYS-k.......
G0RCM1_HYPJQ/819-877               ...............FIVGMLT.NSSP.aMPLGQIAMMLKML.--IP.DGYPWSNEDLQEFLGEKIAEGELELV.GGKYRL........
Q5ADM0_CANAL/744-805               ...............YIVTILQ.NITS..INFERMKTLLNLMvPKDKlDFANVSESLLEEYLDSLVENSKIAFQ.NGNYSL........
G7YX14_CLOSI/805-865               ...............YIVAMLT.NLGG..LSLDRIHSMLRMFaLGST.TTLECNRDELRQFLDKKLHDSELIFD.GETYRL........
A7STC1_NEMVE/511-571               ...............YIVGMLT.NLES..LPLERIHSMLRIFaMQGP.ESAQCSVGDLKRFLDCKVKEQELQFA.NGFYRL........
B0WAC8_CULQU/723-779               ...............YIEAMLT.NLDS..LPLDRIHQMLKMF.---A.SQVDFSQEELKNILQRKVREHKLVYA.GGVYQL........
B4GCG5_DROPE/741-800               ...............YIVGMLT.NLDS..MPIDRIHQMLKLF.ASHS.GGVEFTQDELKHFLQRKVREHKLLFS.GGVYQL........
Q0CK13_ASPTN/1182-1240             ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVSKGKLEIVsGGNYKI........
F2PNL4_TRIEC/851-909               ...............FIKGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFSSEELKQFMGKMVSNGELEMVsGGNYKI........
G5BZF9_HETGA/608-668               ...............YIHAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
E7KRP6_YEASL/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
H2L6C9_ORYLA/738-798               ...............YIQAMLT.NLDS..MTLDRIHSMLRIFvATGP.VVTEMDISELEAFLQKKVREQQLLMS.AGVYRL........
F7VL53_SORMK/1052-1111             ...............YIKGMLT.NASA.sMPLAQMAMMMKML.--IA.DGFPWTNEQLGEFLAEKIAEGEMEVVsGGKYRL........
Q3U430_MOUSE/768-828               ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
H0GK84_9SACH/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
H9KCF0_APIME/533-593               ...............YIVGMLT.NLDS..MPLERIHQMLKMFaSQGP.GAMECGLPELRQFLDRKVREHQLLFS.GGLYRL........
B6Q3P3_PENMQ/1022-1080             ...............FIVGMLT.NQGA..MPLQRIIMMLKIA.--VP.GGFPFGNEELREFLAGMVAQGKLEIVsGGSYKI........
G7DVC9_MIXOS/677-734               ...............FIKGLLA.NMGA..STTEQIHMMLERL.--IP.TYSGSRVDRMAGFLSMLQREGLIDAD.KDKWRL........
B9WER1_CANDC/739-800               ...............YIITILQ.NLTS..INFERMKTLLNLMvPKDKlNFANVNETLLEEYLDSLVEDSKIAFQ.NGNYSL........
Q7Q9T8_ANOGA/724-780               ...............YIEAMLT.NLDS..LPLDRIHQMLKMF.---A.SQVDFTQDELKHILQRKVREHKLVYA.GGVYQL........
Q5SCA3_OSTTA/792-850               ...............YVMGMLT.NFPS..LSLDRIHNMLKMF.-VVD.PVYDKSIEDLEQFLLGLVAQDKLSAD.GTSFS-k.......
F7FKQ0_CALJA/758-818               ...............YIQAMLT.NLES..LSLERIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
H2PU30_PONAB/757-817               ...............YIQAMLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
Q0JC96_ORYSJ/803-862               ...............FIIGMLT.NFGS..MTLDRIHNTLKMF.CIAE.PSYDKSLQQLQSFLSGLVSDEKLEMR.DGSYL-l.......
G3R7Q5_GORGO/757-817               ...............YIQAMLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
Q6F2D1_SOLDE/823-882               ...............FITGMLT.NFGS..MALDRIHNTLKMF.CIAD.PTYDKSLQQLQSFLSGLVAEEKLEFR.DGMY--fl......
C5GEY3_AJEDR/884-942               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFSSEELRGFLSQMVAKGKLEVVsGGSYKI........
B8C5R7_THAPS/697-758               ...............YIVGMLS.NLGQ..LPLERIHTMLKSFtTGSD.HNYNRTPQQLAVFLQQLCKEEKLECSpDGLYKL........
F7G3J3_MACMU/757-817               ...............YIQAMLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
G0VCV7_NAUCC/749-810               ...............YINDMFT.NLGS..LKVDKIHSFLNMSvPRGL.HYSKVTVTQLEAYLDQLVEEEQLIVLpDGSFK-k.......
F4WZV1_ACREC/712-772               ...............YIVGMLT.NLES..LPIERIHQMLKMFaSQGP.GAVECGLPELRQFLDRKVREHQLLLS.GSFYRL........
E2C9F0_HARSA/646-706               ...............YIVGMLT.NLDS..MPLERIHQMLKMFaSQGP.GTVECGLPELKHFLDRKVREHQLLFT.GGLYRL........
I1EG36_AMPQE/138-175               ...............YVTAMLT.NLGP..MSLDKIHNMLSYQ.AQAE.EEGQVSP-------------------.------aal.....
G7JGA9_MEDTR/149-208               ...............FILGMLT.NFGS..MALDRIHNTLKMF.CIAD.PPYDKSLQQLQSFLSGLVSEEKLELR.DGVYF-l.......
ANC2_HUMAN/757-817                 ...............YIQAMLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
E4XA84_OIKDI/614-673               ...............FVRGMIQ.NMNE..IKFDRLTSLLKML.SLHN.PALIIEDDDLKELLDQKQKDKIIEVD.GECYKL........
G7JG99_MEDTR/830-889               ...............FILGMLT.NFGS..MTLDRIHNTLKMF.CIAD.PPYDKSLHQLQSFLSGLVSEEKLELR.DGVYF-l.......
F1NLT0_CHICK/755-815               ...............YIQAMLT.NLES..LSLERIHSMLKMFvMTGP.VVTEIDIQELQGFLQKKVRDQQLIYS.GGVYRL........
D6WHQ9_TRICA/698-757               ...............YILGMLM.NLDT..LPLERIHQMLKMF.AFQG.PTIECNLQELKVFLDRKVREHQLIYS.NGLYRL........
D3BDT3_POLPA/709-766               ...............FVFGMLN.NFKT..LPIDRIHTMLTMF.--NP.ENYSLTTAELKSFLQKLQNEERLEFS.GGEYRI........
G4U6F7_NEUT9/806-865               ...............YIKGMLT.NASA.sMPLAQMAMMMKML.--IA.DGFPWTNEELGEFLAEKIAEGEMELVsGGKYRL........
E7QHY1_YEASZ/784-845               ...............FIEGMLT.NLGA..MKLHKIHSFLKITvPKDW.GYNRITLQQLEGYLNTLADEGRLKYIaNGSYEI........
Q6FJR3_CANGA/718-779               ...............YIKDILL.NLGT..LKIDKLHALLQSAmPKDS.HYSTVNQKQLQDYLDTLVEEGVLSSAsNDSYKL........
F9FM66_FUSOF/806-864               ...............FIVGMLT.NSAP.tMPLGQMLMMMKML.--IP.DGCSWTNEELQEFLAEKVAENKLELA.GGKYRL........
C4WTA5_ACYPI/44-103                ...............YIVGMLI.SLDS..LPLDEIHQILKMF.ATQG.TRVDCSLTQLRLFLDEKVKDHLLIFT.GGRYKL........
F1KZ77_ASCSU/674-732               ..............y-TKSYMA.NQEP..LKPERLHTIFRMF.-ASP.GQQGPSLETVIEFLQRKVKQNLLSCS.NGLYK-v.......
F8P069_SERL9/685-740               ...............FIEGMLT.NLGS..LSLDRIQTMLKFA.----.PGYDRTIDQLGSFMEGAKREGLVTFK.DGMWKL........
B2RYJ1_RAT/771-831                 ...............YIQAMLT.NLES..LSLERIYSMLRMFvMTGP.ALAEIDLQELQGYLQKKVRDQQLIYS.AGVYRL........
C5JT88_AJEDS/884-942               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFSSEELRGFLSQMVAKGKLEVVsGGSYKI........
C1N0W3_MICPC/587-645               ...............YVVGMLT.NFPS..LPLDRIHNMLKMF.-VSE.PPYDKSIDQLEAFLTQLVGEDKLVLE.GTQYR-r.......
C1G921_PARBD/865-923               ...............FIVGMLT.NQGA..MPLQRIIMMLKIV.--VP.GGFPFSSEELRAFLSQMVSKGKLEVVsGGSYKI........
B0XVH2_ASPFC/834-892               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVAKGKLEIIsGGNYKL........
H2ZEA6_CIOSA/122-181               ...............YIKGMLK.NFQS..LPLDRIHKMLQMF.AIND.SNMQIELSQLKRILNENVQQGYLVIE.AGKFKL........
H2QY82_PANTR/704-761               ..............l----MLT.NLES..LSLDRIYNMLRMFvVTGP.ALAEIDLQELQGYLQKKVRDQQLVYS.AGVYRL........
G3N1P9_BOVIN/156-216               ...............YIQAMLT.NLES..LSLERIYSMLRMFvVTGP.ALAEIDLQELQGFLQRKVRDQQLVYS.AGVYRL........
H9I127_ATTCE/759-819               ...............YIVGMLT.NLES..LPIERIHQMLKMFaSQGP.GAVECGLPELRQFLDRKVREHQLLLS.GSFYRL........
C8VLZ0_EMENI/858-916               ...............FIVGMLT.NQGA..MPLQRIVMMLKIA.--VP.GGFPFSNEELREFLAGMVSKGKIEIVsGGNYKI........
#=GC SS_cons                       ...............HHHHHHH.HH-S..EEHHHHHHHHHHHS-GGG.--TT--HHHHHHHHHHHHHTTSEE--TTTEEEE........
#=GC seq_cons                      ...............aIhGMLT.Nhsu..hsL-RIapMLKhh...ss.sshsho.pELppFLsphVp-tcLphs.uGsY+l........
//
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