GenomeNet

Database: Pfam
Entry: ATG19_autophagy
LinkDB: ATG19_autophagy
Original site: ATG19_autophagy 
#=GF ID   ATG19_autophagy
#=GF AC   PF12744.2
#=GF DE   Autophagy protein Atg19, Atg8-binding
#=GF AU   Wood V, Coggill P
#=GF SE   Wood V
#=GF GA   25.00 25.00;
#=GF TC   34.90 32.90;
#=GF NC   21.30 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   16247502
#=GF RT   Autophagy: molecular machinery for self-eating.
#=GF RA   Yorimitsu T, Klionsky DJ;
#=GF RL   Cell Death Differ. 2005;12:1542-1552.
#=GF RN   [2]
#=GF RM   11430817
#=GF RT   Cvt19 is a receptor for the cytoplasm-to-vacuole targeting
#=GF RT   pathway.
#=GF RA   Scott SV, Guan J, Hutchins MU, Kim J, Klionsky DJ;
#=GF RL   Mol Cell. 2001;7:1131-1141.
#=GF RN   [3]
#=GF RM   17192412
#=GF RT   Atg19 mediates a dual interaction cargo sorting mechanism in
#=GF RT   selective autophagy.
#=GF RA   Chang CY, Huang WP;
#=GF RL   Mol Biol Cell. 2007;18:919-929.
#=GF RN   [4]
#=GF RM   19236009
#=GF RT   ATG systems from the protein structural point of view.
#=GF RA   Noda NN, Ohsumi Y, Inagaki F;
#=GF RL   Chem Rev. 2009;109:1587-1598.
#=GF DR   INTERPRO; IPR024543;
#=GF CC   Autophagy is generally known as a process involved in the
#=GF CC   degradation of bulk cytoplasmic components that are
#=GF CC   non-specifically sequestered into an autophagosome, where they
#=GF CC   are sequestered into double-membrane vesicles and delivered to
#=GF CC   the degradative organelle, the lysosome/vacuole, for breakdown
#=GF CC   and eventual recycling of the resulting macromolecules. In
#=GF CC   contrast to autophagy, however, the Cvt pathway is a highly
#=GF CC   selective process that involves the sequestration of at least
#=GF CC   two specific cargos that are resident vacuolar hydrolases,
#=GF CC   aminopeptidase I (Ape1) and alpha-mannosidase (Ams1). These
#=GF CC   proteins are sequestered within a double-membrane vesicle,
#=GF CC   termed a Cvt vesicle. The Cvt vesicle is fairly consistent in
#=GF CC   size, and is much smaller than the autophagosome, being 140-160
#=GF CC   nm in diameter. The prApe1 is sequestered within either Cvt
#=GF CC   vesicles or autophagosomes, depending on the nutrient
#=GF CC   conditions, and delivered to the vacuole. Autophagy and the Cvt
#=GF CC   pathway are topologically and mechanistically similar and share
#=GF CC   most of the same machinery. The Ape1 complex is ultimately
#=GF CC   enwrapped within either Cvt vesicles or autophagosomes at the
#=GF CC   perivacuolar PAS. The receptor protein Atg19 binds to the Ape1
#=GF CC   complex through the prApe1 propeptide to form the Cvt complex in
#=GF CC   the cytosol. In the absence of Atg19, prApe1 can form an Ape1
#=GF CC   complex, but does not localise at the PAS. Atg19 is a peripheral
#=GF CC   membrane protein with differing binding sites for both Ape1 and
#=GF CC   Ams1. The Atg8-binding region in the yeast proteins is this very
#=GF CC   C-terminal residues [3].
#=GF SQ   35
#=GS E7M000_YEASV/194-415  AC E7M000.1
#=GS E7NN61_YEASO/194-415  AC E7NN61.1
#=GS C8ZHN4_YEAS8/162-412  AC C8ZHN4.1
#=GS C5DNC2_LACTC/271-505  AC C5DNC2.1
#=GS H0H0S3_9SACH/79-324   AC H0H0S3.1
#=GS E7KI16_YEASA/194-415  AC E7KI16.1
#=GS G8BMN5_TETPH/140-401  AC G8BMN5.1
#=GS G2WMF3_YEASK/194-415  AC G2WMF3.1
#=GS E7Q927_YEASB/194-415  AC E7Q927.1
#=GS A6ZNC7_YEAS7/162-412  AC A6ZNC7.1
#=GS B5VRH1_YEAS6/162-412  AC B5VRH1.1
#=GS B3LIY0_YEAS1/162-412  AC B3LIY0.1
#=GS E7Q926_YEASB/162-412  AC E7Q926.1
#=GS Q757I4_ASHGO/340-564  AC Q757I4.2
#=GS G8ZTZ3_TORDC/227-462  AC G8ZTZ3.1
#=GS G2WMF2_YEASK/162-412  AC G2WMF2.1
#=GS ATG34_YEAST/162-412   AC Q12292.1
#=GS ATG34_YEAST/162-412   DR PDB; 2KZK A; 246-348;
#=GS ATG19_YEAS7/194-415   AC A6ZNC8.1
#=GS ATG19_YEAST/194-415   AC P35193.1
#=GS ATG19_YEAST/194-415   DR PDB; 2ZPN H; 1-4;
#=GS ATG19_YEAST/194-415   DR PDB; 2KZB A; 254-367;
#=GS ATG19_YEAST/194-415   DR PDB; 2ZPN E; 1-4;
#=GS ATG19_YEAST/194-415   DR PDB; 2ZPN G; 1-4;
#=GS ATG19_YEAST/194-415   DR PDB; 2ZPN F; 1-4;
#=GS E7R9D9_PICAD/325-488  AC E7R9D9.1
#=GS Q6CTN9_KLULA/337-593  AC Q6CTN9.1
#=GS G0V9K5_NAUCC/150-417  AC G0V9K5.1
#=GS H0GN45_9SACH/194-415  AC H0GN45.1
#=GS C8ZHN6_YEAS8/194-415  AC C8ZHN6.1
#=GS A7KAK2_PICAN/325-488  AC A7KAK2.1
#=GS G0W6A4_NAUDC/702-907  AC G0W6A4.1
#=GS E7QKE0_YEASZ/162-412  AC E7QKE0.1
#=GS H0H0S4_9SACH/193-421  AC H0H0S4.1
#=GS B5VRH2_YEAS6/194-415  AC B5VRH2.1
#=GS C7GK47_YEAS2/162-412  AC C7GK47.1
#=GS B3LIY1_YEAS1/194-415  AC B3LIY1.1
#=GS H2ARX1_KAZAF/266-419  AC H2ARX1.1
#=GS C7GK46_YEAS2/194-415  AC C7GK46.1
#=GS E7QKE1_YEASZ/194-415  AC E7QKE1.1
#=GS C5DR64_ZYGRC/270-463  AC C5DR64.1
E7M000_YEASV/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
E7NN61_YEASO/194-415             ......................................................g-TIDIPEDRSELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNXNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAA...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
C8ZHN4_YEAS8/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNKDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGDTILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
C5DNC2_LACTC/271-505             .......................................................VIIDIPDRNARVFDFFS.....KIKTEEQLAQLINHYEKYEN...LLAQVSGDDA..KLQEAV---A.LILSPCKTNSLDASIE.....--TAHEEEDLIDVQMGKRDHVISFKLNNRGPRPVSSGLRLVFqy...fepRNANPVK...CTLHMGPHEFQKDSYKTLNFnc..........rgLIENFSLGNPCKIDLVD...QDDDVIFTGSS..S...G..G.P.NMCL.K....QPIMFDI....QQ.SVYSE...........AR..EVPDLEAD.SI--..-EDQ.DIISNTVTNE--.......GSQHASRD.DSELD............
H0H0S3_9SACH/79-324              ......................................................k-YVVLPEDKPELVEFFS.....HLKTSEQLQEIYNGYRVYET...LLQKFDGHKE..KMHSFLHEGT.SVPEGESMEQIALFEEpkeknEALATPDDRSLRVDVNHEDNSLHFILYNNADLIVPGNCTFEF.......sSSASKV-...YSIKMGPHEIGPKGQKELWY..............FPSLSAPLVDYTIKIIN...QNGDVIFIGKC..T...E..S.N.EVTL.K....SALSSFS....TG.SFNTL...........QD..PNNVFRAD.ALSS..FDES.SVMSSPFSNEIDei..ydsGSTLNRPF.TWEEI............
E7KI16_YEASA/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEGGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
G8BMN5_TETPH/140-401             ......................................................t-IIDIPESNSKVYDFFS.....KIETVSELEEVMNGYLKWKE...----VEQRDN..VCDQEINNKN.EVVGHPSVRS-DISSKp..gtDDLVNENQVVLAVEITKSDYLIEFNVIHEGEKDLPSDLRLAY........-HDESIK..iNDLPLGKHPLKAGRNKTIKCntfnllntttggvtSSNNHTTRQNYIYIYDP...SDDSVQYIANI..A...T..PqT.KVYLeK....AP--MLS....AH.NLQKYemls..spsllKE..QNNNTQSK.---S..EDDN.DIISTTVTNTTLshnprntKSTNSRRIsDWE--dy..........
G2WMF3_YEASK/194-415             ......................................................g-TIDIPEDRSELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
E7Q927_YEASB/194-415             ......................................................g-TIDIPEDRSELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAA...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
A6ZNC7_YEAS7/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNEDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGETILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIVSTPFLGETDev..ynsGSTLSRPF.TWEEI............
B5VRH1_YEAS6/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNKDNSLHFILYNKTNIIIPGTCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGDTILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
B3LIY0_YEAS1/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNKDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGDTILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
E7Q926_YEASB/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNEDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGETILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
Q757I4_ASHGO/340-564             vcifapdisvaaatlfsqvhdvkdleriasqcaayeslvprfgasaeelerklss-----------------.....--------------------...----------..----------.---------------L.....PPKATEDEFGISVTVSRVDFALTFRLRNYTTDAIPSSSSLVFsh...hpvGGSSHT-...RTMSIGPHELPPGSSKQLNI.............cYPHQTSDGDPYSLSLVS...PAGTALYSGKA..S...S..M.PaDILL.AcpggTPASSAA....FN.AMYTNqssasvpapvvNA..PFRQSNSP.VMPS..DEEY.DLLSDSDI----.......--------.-----ev..........
G8ZTZ3_TORDC/227-462             ......................................................v-VIDIADDRKDLFDLFS.....KME---NLEEIVHGFRLYKK...WTEKLSEE--..KIE-------.GILSGEEFSAKNRRFE.....--VA--KPGKLEVELKKKDKAIIFQMRNTGASTVAGGLTLVYstfkeddnLDASNVT...CELPMGPHELLPGNSKMLKFny..........fgVLSDISMETKSQIALVD...SEKNFIFKGTN..S...GraG.S.HFIL.N....ST--GLA....SD.GIAGD...........LP..LLNRRDSL.QLLE..KDDSdSVISSTVTNDN-.......-ETLHS--.-----vsdqetsnwdey
G2WMF2_YEASK/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNEDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGETILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
ATG34_YEAST/162-412              .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFGGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNEDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGETILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
#=GR ATG34_YEAST/162-412   SS    .......................................................XXXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXX...XXXXXXXXXX..XXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXX--S--EEEE--BTTB--EEEE--SSS---SS-EEEB........----SSS-.-B--B--SS---SS-EEE---..............SS---S--TT---EEE-...TTS-EEEE---..-...S..S.S.--B-.-....---XXXX....XX.XXXXXXX......XXXXX..XXXXXXXX.XXXX..XXXX.XXXXXXXXXXXXXX..XXXXXXXXXXX.XXXXX............
ATG19_YEAS7/194-415              ......................................................g-TIDIPEDRSELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMDQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
ATG19_YEAST/194-415              ......................................................g-TIDIPEDRSELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
#=GR ATG19_YEAST/194-415   SS    ......................................................X-XXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXX...XXXXXXXX--..---------X.XXXXXXXXXXXXXXXX.....----XSSXXXEEEEEEEETTEEEEEEEEXSSSXXXSSXEEXXXS...SSSSXXXXX-...--EEXXSXXXXTTXXEEEEE..............XSXXXXXXTTXXEEEEX...TTSSEEEEEXX..X...S..S.S.XEEX.X....XS-SXXX....XX.XXXXX...........XX..XXXXXXXX.XXXX..XXXX.XXXXXXXXXXXX.......XXXXXXXX.X-EE-............
E7R9D9_PICAD/325-488             ......................................................l-LVQLIEDHNMMKNYNAgtvgiEVSCTKQNSRIFQ-LALTNR...LARDILKPEL..KTFIGEVKKT.FMITPNVFKNGSTRYL.....MLDTADWGDSFSSTSSILNGILGFTLEVWEDQALVAKGGLDF........NSGNALS...LLVAVTDPKSAPRKH-----..............LGETGSTLKESEPEFVM...VDGDL------..-...-..-.-.----.-....-------....--.-----...........--..--------.----..----.------------.......--------.-----s...........
Q6CTN9_KLULA/337-593             ......................................................v-IIEVGQQNKAMFDFFA.....EIKTESELEKLMQ-DAISWR...IAKQWYGEDIyeKLERYQ----.NMMQENAQKERENESSde.atMNTQGSSNPSLRVEMFQKGHLLTFKLFNDGDETIPNGLKLVFqce..qkgRVATPIK...CNLQVGPDELQPGNYKILNFny..........rgTLEEFSFEQPCKIDLID...VREQVVYTTEQ..StvpG..S.S.VFHL.K....PPVCKMLpmgdRR.NIPCN...........ED..EDPDVQYTlTSPS..QSDT.DVISSSVTDQEE.......EEEEEEEE.E----eeeeee......
G0V9K5_NAUCC/150-417             ................sskqlqleysnkvsetvvedrleesnniyvkndlyqkin-----------------.....ELLSKTKINDIIHGYEKYTEwigLCQDNEDEVR..KILTNNNEETaTIQVDDEPKNSFINDA.....TSLSASMVPVITMNYQIKDFHVEFTLHNCGTSTLSGGLNFVFqy...qtdSGNNIIE...HQIDMGPHDLKPDCKKILKFm............sLNMINTNLEILSVNVVG...IDGRVIYVGKKdaE...K..N.N.QFNL.T....HP--ILS....AE.HLETN...........EEffSVYSFHQK.QEPSepVDTT.DVISTTITN---.......--DNATKF.TWEE-y...........
H0GN45_9SACH/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
C8ZHN6_YEAS8/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
A7KAK2_PICAN/325-488             ......................................................l-LVQLIEDHNMMKNYNAgakgiEVSCTKQNSRILQ-LAFTNR...LARDILKPDL..KTVIGEVTKT.FMITPNVFKNGSTRYL.....MLDTADWGDLFSSTGSTINGTLGFTLEVWEDQTLAAKGSLDF........NSSNALS...LLVDVSDPKSAPRKH-----..............LEETCSNLKESEPEFVM...VDGDL------..-...-..-.-.----.-....-------....--.-----...........--..--------.----..----.------------.......--------.-----s...........
G0W6A4_NAUDC/702-907             ...................................................elet--------DDETHDFIS.....TLKTSEDLKKVVNGYPKFKE...WRYIGGKDES..EIDERFSSKD.NMIAQVSINHELENIK.....KPEEFLNSTALEVTMERRYKDIKFTLTNRGKSDLPGNSKFVVqys..iehHGVAHVA..dVTLDMGPHKLLIGSKKHLLW..............SPP-CPIHNGIVVDVVElstEDGFVFYSGKV..H...D..-.N.NFEL.S....TP--ALS....YE.HLEVN...........EQ..--------.----..----.------------.......--------.-----yynslekrk...
E7QKE0_YEASZ/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVZVSNKDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGDTILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
H0H0S4_9SACH/193-421             ......................................................g-TIDIPEDNPELVSFFT.....ELKTVKQLENVFQRYHDYES...LLAKCCAE--..--TETETTKD.-LLKEEIAVSKNAEVS.....---ERLDDRSLQVTVNYRDGSLYFHLYNNTNSVLAGNCKLKFtn...dndKPTTRI-...--IEMGPHEIGIKEHKELRY..............FPYTPELITSSTIAIEN...EYEEVIFVGKH..G...R..S.P.RVSL.K....PP-SRLS....VE.SLQAS...........QD..HFYDFRID.SLPE..LDDS.SIISTSISLSCE.......DDDCGKAM.TWEEL............
B5VRH2_YEAS6/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
C7GK47_YEAS2/162-412             .......................................................KCIILPEDKPELIKFFS.....KFETSVQLQEVYEGYKVYEK...LLQKFDGQKK..RMESFLNENT.PMSGAEAIKQINISEElkekgERLTTPNDPLLHVEVSNEDNSLHFILYNKTNIIIPGNCTFEF........--SSQISe.vFSIKMGPHEIGIKGQKELWF..............FPSLPTPLSNYTMKVVN...QDGETILVGKC..A...D..S.N.EITL.K....SPLASFS....TG.SFQTGsf......htlQD..PTNVFRAD.ALSS..PDES.SIMSTPFLGETDev..ynsGSTLSRPF.TWEEI............
B3LIY1_YEAS1/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
H2ARX1_KAZAF/266-419             ......................................................v-FIDIDPKNRRLFEYFS.....KIASEADLEKLLSNSQKYEG...LLQRFDNDET..LLLSEL----.SHLSLNNSDTSSIKHE.....--EPTEMGIPFELKVYEKDLNVCFELSNGTDTYFSENLYLLIh.....yiSSENEIW..kTKIDIC-HGIGPKSKRIFTK..............FKSF-------------...-----------..-...-..-.-.----.-....-------....--.-----...........--..--------.----..----.------------.......--------.-----fekkggdfsie.
C7GK46_YEAS2/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
E7QKE1_YEASZ/194-415             ......................................................g-TIDIPEDRPELVNFFT.....ELKTVKQLEDVFQRYHDYER...LSQECDSK--..---------T.EIASDHSKKETKIEVE.....----PPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFtd...agdKPTTQI-...--IDMGPHEIGIKEYKEYRY..............FPYALDLEAGSTIEIEN...QYGEVIFLGKY..G...S..S.P.MINL.R....PP-SRLS....AE.SLQAS...........QE..PFYSFQID.TLPE..LDDS.SIISTSISLSYD.......GDDNEKAL.TWEEL............
C5DR64_ZYGRC/270-463             ..............................................ycahqakaa-----------------.....--------------------...----------..----------.-------------SSE.....KPRSRHEFASLEITVSHRDDLLTFDIYNNGRRALPGDCTLVLa.....tcDSSTSGSrptVESYLGPHELRPGNRKLFHK..............KISRGSVIECARIDILDg.kNKEEVLYTGSS..S...WllD.T.SIKL.K....PPRLSKS....PSpSPTATltp....saapED..QSSCKPLS.SL-A..KEDE.GVISSSMTNDEYs.....lCSDSGSDT.NWEE-y...........
#=GC SS_cons                     ......................................................X-XXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXX...XXXXXXXX--..---------X.XXXXXXXXXXXXXXXX.....----XSSXSXEEEEEEEETTEEEEEEEEXSSSXXXSSXEEEBXS...SSSSXXXSSS...B-EEXXSSXXXTTXEEEEEE..............SSXXXSXXTTXXEEEEX...TTSSEEEEEXX..X...S..S.S.XEEX.X....XS-SXXX....XX.XXXXX...........XX..XXXXXXXX.XXXX..XXXX.XXXXXXXXXXXX.......XXXXXXXX.X-EE-............
#=GC seq_cons                    ......................................................s.sIplPED+sELlsFFo.....clcTspQLp-VaptY+sYE+...L.QchDuc.............T..huuscuhKptpIp.E.........sPN-tsLplshsp+DNSLaFpLaNpTNpllsGNCpLcFp......spsooQI......IcMGPHEIGIKphKEhpa..............FP.thsh.us.Tlcl.N...Q.G-VIalGKh..u...s..S.s..IsL.+....sP.uphS....sp.ShQsu...........Q-..Ph.sFphD.sLsp...D-S.SIlSTohohphD.......Gss.p+sh.TWEEl............
//
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