GenomeNet

Database: Pfam
Entry: Afi1
LinkDB: Afi1
Original site: Afi1 
#=GF ID   Afi1
#=GF AC   PF07792.7
#=GF DE   Docking domain of Afi1 for Arf3 in vesicle trafficking
#=GF PI   DUF1630;
#=GF AU   Fenech M
#=GF SE   Pfam-B_9160 (release 14.0)
#=GF GA   25.50 25.50;
#=GF TC   26.00 25.50;
#=GF NC   24.90 25.20;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   18397879
#=GF RT   Afi1p functions as an Arf3p polarization-specific docking factor
#=GF RT   for development of polarity.
#=GF RA   Tsai PC, Lee SW, Liu YW, Chu CW, Chen KY, Ho JC, Lee FJ;
#=GF RL   J Biol Chem. 2008;283:16915-16927.
#=GF DR   INTERPRO; IPR012860;
#=GF CC   This domain occurs at the N-terminal of Afi1, an
#=GF CC   Arf3p-interacting protein, is a protein necessary for vesicle
#=GF CC   trafficking in yeast. This domain is the interacting region of
#=GF CC   the protein which binds to Arf3, the highly conserved small
#=GF CC   GTPases (ADP-ribosylation factors). Afi1 is distributed
#=GF CC   asymmetrically at the plasma membrane and is required for
#=GF CC   polarized distribution of Arf3 but not of an Arf3 guanine
#=GF CC   nucleotide-exchange factor, Yel1p. However, Afi1 is not required
#=GF CC   for targeting of Arf3 or Yel1p to the plasma membrane. Afi1
#=GF CC   functions as an Arf3 polarization-specific adapter and
#=GF CC   participates in development of polarity. Although Arf3 is the
#=GF CC   homologue of human Arf6 it does not function in the same way,
#=GF CC   not being necessary for endocytosis or for mating factor
#=GF CC   receptor internalization. In the S phase, however, it is
#=GF CC   concentrated at the plasma membrane of the emerging bud. Because
#=GF CC   of its polarized localisation and its critical function in the
#=GF CC   normal budding pattern of yeast, Arf3 is probably a regulator of
#=GF CC   vesicle trafficking, which is important for polarized growth.
#=GF SQ   156
#=GS E7KUE5_YEASL/26-218   AC E7KUE5.1
#=GS B2AXK1_PODAN/123-294  AC B2AXK1.1
#=GS G3AQQ9_SPAPN/3-125    AC G3AQQ9.1
#=GS F2SUH9_TRIRC/91-226   AC F2SUH9.1
#=GS F2S989_TRIT1/91-212   AC F2S989.1
#=GS F9WBR8_TRYCI/13-127   AC F9WBR8.1
#=GS E9BM16_LEIDB/15-142   AC E9BM16.1
#=GS E9DDS1_COCPS/90-249   AC E9DDS1.1
#=GS YG76_SCHPO/2-128      AC O94674.1
#=GS F2TNB3_AJEDA/90-246   AC F2TNB3.1
#=GS G4U3C0_PIRID/9-136    AC G4U3C0.1
#=GS Q0V5R0_PHANO/110-273  AC Q0V5R0.1
#=GS G8ZT84_TORDC/13-149   AC G8ZT84.1
#=GS B0XMM8_ASPFC/81-200   AC B0XMM8.1
#=GS G7X9K5_ASPKW/82-241   AC G7X9K5.1
#=GS F4R6H2_MELLP/60-233   AC F4R6H2.1
#=GS E7L9A4_TRYCR/18-161   AC E7L9A4.1
#=GS A8PX95_MALGO/19-149   AC A8PX95.1
#=GS D4D1A5_TRIVH/91-226   AC D4D1A5.1
#=GS G8BJ22_CANPC/3-125    AC G8BJ22.1
#=GS C7GML0_YEAS2/26-218   AC C7GML0.1
#=GS F9G8Q1_FUSOF/129-262  AC F9G8Q1.1
#=GS D2W4R6_NAEGR/231-383  AC D2W4R6.1
#=GS G4N038_MAGO7/133-304  AC G4N038.1
#=GS Q23F93_TETTS/1-140    AC Q23F93.1
#=GS C4R3J0_PICPG/6-134    AC C4R3J0.1
#=GS Q75BQ9_ASHGO/49-219   AC Q75BQ9.2
#=GS A7TRE4_VANPO/73-251   AC A7TRE4.1
#=GS B8MY96_ASPFN/80-205   AC B8MY96.1
#=GS G2QD70_THIHA/105-282  AC G2QD70.1
#=GS F8QFS0_SERL3/7-138    AC F8QFS0.1
#=GS F7W328_SORMK/124-292  AC F7W328.1
#=GS A2Q8P4_ASPNC/82-239   AC A2Q8P4.1
#=GS E4V050_ARTGP/91-226   AC E4V050.1
#=GS B5VS19_YEAS6/1-133    AC B5VS19.1
#=GS A1CRY6_ASPCL/85-243   AC A1CRY6.1
#=GS I1RRG0_GIBZE/71-241   AC I1RRG0.1
#=GS Q6CGA4_YARLI/9-124    AC Q6CGA4.1
#=GS F0XQA1_GROCL/147-345  AC F0XQA1.1
#=GS H3GE73_PHYRM/13-141   AC H3GE73.1
#=GS F8MMJ6_NEUT8/122-288  AC F8MMJ6.1
#=GS D5GKQ5_TUBMM/42-159   AC D5GKQ5.1
#=GS G4UQP2_NEUT9/122-288  AC G4UQP2.1
#=GS E9BZT8_CAPO3/13-258   AC E9BZT8.1
#=GS H8X3W9_9ASCO/3-125    AC H8X3W9.1
#=GS E7QKR4_YEASZ/5-83     AC E7QKR4.1
#=GS E3QCC1_COLGM/118-260  AC E3QCC1.1
#=GS C8ZI91_YEAS8/26-218   AC C8ZI91.1
#=GS Q7RXB5_NEUCR/122-246  AC Q7RXB5.2
#=GS Q55YB7_CRYNB/14-162   AC Q55YB7.1
#=GS G0RJ82_HYPJQ/111-286  AC G0RJ82.1
#=GS G8YLF0_PICSO/3-125    AC G8YLF0.1
#=GS F2QXF7_PICP7/6-134    AC F2QXF7.1
#=GS F4PES0_BATDJ/13-193   AC F4PES0.1
#=GS B9WE52_CANDC/3-125    AC B9WE52.1
#=GS D3BKL1_POLPA/333-466  AC D3BKL1.1
#=GS G0VJ47_NAUCC/27-198   AC G0VJ47.1
#=GS G8YNS9_PICSO/3-125    AC G8YNS9.1
#=GS I1CGI0_RHIO9/6-109    AC I1CGI0.1
#=GS D2V9C8_NAEGR/7-162    AC D2V9C8.1
#=GS G3B9I0_CANTC/3-124    AC G3B9I0.1
#=GS A8N5K3_COPC7/7-144    AC A8N5K3.1
#=GS H0GNP3_9SACH/26-218   AC H0GNP3.1
#=GS E9F477_METAR/111-276  AC E9F477.1
#=GS Q0CUX1_ASPTN/72-232   AC Q0CUX1.1
#=GS Q4WKC8_ASPFU/81-200   AC Q4WKC8.1
#=GS G8BYZ7_TETPH/47-206   AC G8BYZ7.1
#=GS A0C6F7_PARTE/1-181    AC A0C6F7.1
#=GS E2L8K6_MONPE/5-62     AC E2L8K6.1
#=GS E7Q9P2_YEASB/26-218   AC E7Q9P2.1
#=GS Q55D43_DICDI/112-257  AC Q55D43.1
#=GS Q6CPS0_KLULA/28-197   AC Q6CPS0.1
#=GS D3BKL1_POLPA/154-252  AC D3BKL1.1
#=GS AFI1_YEAST/26-218     AC Q99222.1
#=GS A6RVU6_BOTFB/70-232   AC A6RVU6.1
#=GS D7G403_ECTSI/14-161   AC D7G403.1
#=GS C9SV70_VERA1/118-292  AC C9SV70.1
#=GS B9RE36_RICCO/27-178   AC B9RE36.1
#=GS C6HAC6_AJECH/90-246   AC C6HAC6.1
#=GS C5P112_COCP7/90-249   AC C5P112.1
#=GS D2VQ16_NAEGR/2-155    AC D2VQ16.1
#=GS D4AJX3_ARTBC/91-226   AC D4AJX3.1
#=GS C4Y911_CLAL4/3-125    AC C4Y911.1
#=GS E3RFI2_PYRTT/104-276  AC E3RFI2.1
#=GS Q4D5Z4_TRYCC/14-147   AC Q4D5Z4.1
#=GS B2WB45_PYRTR/51-218   AC B2WB45.1
#=GS D4AU15_ARTBC/28-126   AC D4AU15.1
#=GS E4ZT50_LEPMJ/111-279  AC E4ZT50.1
#=GS G1XGV3_ARTOA/66-156   AC G1XGV3.1
#=GS D8QBP3_SCHCM/7-137    AC D8QBP3.1
#=GS C7YNT7_NECH7/126-297  AC C7YNT7.1
#=GS F0ULC4_AJEC8/90-246   AC F0ULC4.1
#=GS G2YRD1_BOTF4/130-292  AC G2YRD1.1
#=GS F9WZ87_MYCGM/85-247   AC F9WZ87.1
#=GS I1BNQ9_RHIO9/4-119    AC I1BNQ9.1
#=GS F4QE10_DICFS/103-353  AC F4QE10.1
#=GS B8MHD8_TALSN/85-247   AC B8MHD8.1
#=GS A6ZNX6_YEAS7/26-218   AC A6ZNX6.1
#=GS Q5KLM3_CRYNJ/14-162   AC Q5KLM3.1
#=GS Q2H6V1_CHAGB/196-367  AC Q2H6V1.1
#=GS G2R9J9_THITE/121-291  AC G2R9J9.1
#=GS Q55D43_DICDI/384-492  AC Q55D43.1
#=GS G0UNX7_TRYCI/13-123   AC G0UNX7.1
#=GS B0D0E4_LACBS/6-143    AC B0D0E4.1
#=GS Q6BI40_DEBHA/9-132    AC Q6BI40.2
#=GS A4I5V0_LEIIN/15-145   AC A4I5V0.1
#=GS C5JQA6_AJEDS/90-246   AC C5JQA6.1
#=GS Q4P9F2_USTMA/25-158   AC Q4P9F2.1
#=GS C5GBC1_AJEDR/90-246   AC C5GBC1.1
#=GS G0SZG0_RHOG2/29-170   AC G0SZG0.1
#=GS C5FTF7_ARTOC/91-227   AC C5FTF7.1
#=GS F0ZTU4_DICPU/309-438  AC F0ZTU4.1
#=GS C4JVY8_UNCRE/89-247   AC C4JVY8.1
#=GS C0NC17_AJECG/90-246   AC C0NC17.1
#=GS D2VRW9_NAEGR/60-245   AC D2VRW9.1
#=GS A7EPQ6_SCLS1/130-292  AC A7EPQ6.1
#=GS E6QZ55_CRYGW/14-161   AC E6QZ55.1
#=GS C1GKI9_PARBD/91-250   AC C1GKI9.1
#=GS A3GHI4_PICST/3-125    AC A3GHI4.2
#=GS H0H162_9SACH/26-219   AC H0H162.1
#=GS H1V9B3_COLHI/118-291  AC H1V9B3.1
#=GS E9EBE0_METAQ/111-275  AC E9EBE0.1
#=GS G3J5M9_CORMM/112-284  AC G3J5M9.1
#=GS Q2URL2_ASPOR/80-239   AC Q2URL2.1
#=GS C0SET4_PARBP/168-288  AC C0SET4.1
#=GS D0MTX1_PHYIT/14-147   AC D0MTX1.1
#=GS C5DZH0_ZYGRC/8-142    AC C5DZH0.1
#=GS C5M7V5_CANTT/3-125    AC C5M7V5.1
#=GS F2PTM1_TRIEC/91-226   AC F2PTM1.1
#=GS F0ZTU4_DICPU/95-230   AC F0ZTU4.1
#=GS MESA_EMENI/79-241     AC Q5BGR2.2
#=GS A1D4W9_NEOFI/81-208   AC A1D4W9.1
#=GS F8NI12_SERL9/7-138    AC F8NI12.1
#=GS G7E913_MIXOS/3-139    AC G7E913.1
#=GS B6QMP6_PENMQ/85-245   AC B6QMP6.1
#=GS G2X7J5_VERDV/118-292  AC G2X7J5.1
#=GS H6C574_EXODN/42-200   AC H6C574.1
#=GS B6HSJ1_PENCW/75-232   AC B6HSJ1.1
#=GS G9ND52_HYPVG/110-287  AC G9ND52.1
#=GS F0VZ52_9STRA/41-164   AC F0VZ52.1
#=GS G3XSB1_ASPNA/82-239   AC G3XSB1.1
#=GS B3LJH1_YEAS1/26-218   AC B3LJH1.1
#=GS G9P6A1_HYPAI/70-237   AC G9P6A1.1
#=GS G0SHI3_CHATD/69-213   AC G0SHI3.1
#=GS E7A2F3_SPORE/27-156   AC E7A2F3.1
#=GS A5DM71_PICGU/25-147   AC A5DM71.2
#=GS C5DJD2_LACTC/29-192   AC C5DJD2.1
#=GS Q4DMT0_TRYCC/18-158   AC Q4DMT0.1
#=GS E7M0D3_YEASV/26-218   AC E7M0D3.1
#=GS A6R562_AJECN/90-245   AC A6R562.1
#=GS C4YQL5_CANAW/3-125    AC C4YQL5.1
#=GS A5DZ96_LODEL/3-125    AC A5DZ96.1
#=GS G2WN04_YEASK/26-218   AC G2WN04.1
#=GS Q5ANI4_CANAL/3-125    AC Q5ANI4.1
#=GS G0W7P9_NAUDC/32-217   AC G0W7P9.1
#=GS C1H4C3_PARBA/91-250   AC C1H4C3.1
E7KUE5_YEASL/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
B2AXK1_PODAN/123-294             ............................................HVEYILVASFDIDRGPIMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTVFF.LHKDSSQEEDDAErqa............kesrR------.Arrrrrrd....................rakgiihESDDEDDGGEEdlddddd....................................................................................dwdddvsTDEEPEGGEG.....PPLVYVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
G3AQQ9_SPAPN/3-125               ............................................NIEYIITAQFDIDKGPSLIHQYPHELAG...............................SK..NLYFLPE.......LMIPDQIHKRDE.....DYTLFL.LYKDIQTGEFQYK...................FEKD---.-..................................-----------..................................................................................................-------KCD.....PCPYFLYTVVV.NRTDDSFKRGSQIKSLSIVTKLSYFKNFRPLLLICL-d.............................................................................................................
F2SUH9_TRIRC/91-226              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDNGGPEEDPEfg...............edK---DGD.D.................................eQDEEKNQD--Dls.............................................................................................qeyPEEDDAGS--.....----------A.GMDDEPPLIGAMVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
F2S989_TRIT1/91-212              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDNGGPEEDPEfg...............edKDGDDEQ.-..................................DEEKNQDDLSQey..............................................................................................peE--DDAGSAGmd.dePPLMYVLNLVN.TKQDTS-------------------------------p.............................................................................................................
F9WBR8_TRYCI/13-127              ..........................................fl--HQLLLAEFDIDIGSCIRVRYPQDLTSyisqrdsagvgd.......vdeavssqhkiiQE..DDTVFAN.......YMMPDGSEKHVV.....GRTVFI.VSRP---------...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------ipvvtasfslycfslvesssdapddsalgtsk..............................................................................
E9BM16_LEIDB/15-142              .........................................ats----VIVAEFDIDTGACLRACYPP-VPTspstallss............iesgappgiaG-..HTEYFAN.......VMLPDGAEKVNV.....TRTVFV.VNRPQPP------...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------lylrfpvyrfarasastgstdtqaawerrpgeetaryvpeillinattee............................................................
E9DDS1_COCPS/90-249              ............................................HVEYILVASFHVDRGPIMEHQYPAAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTMFF.LHRDAGSEDENEYgddsqg......qaekavdE------.Akedsq........................dghdqTEDEEATDDDG..................................................................................................DDDDEEAGDG.....PPLMYVLNLVN.TKQDNSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
YG76_SCHPO/2-128                 ...........................................q-IDYLLTAIFDPDRGPVLQYQCPEN--G...............................EA.sDLHFLAE.......LMLPDRVHERRE.....DWSLFF.IHFSKKSNVFSLF...................SN-----.-..................................-----------..................................................................................................VDDINFEPSD.....SNMYYVLNTIR.AKRVEGTRRGGSVFAMAICTTFPHVHALKPLLD----tawe..........................................................................................................
F2TNB3_AJEDA/90-246              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGSEEENEYvep............tagqQ----T-.Eyn..............................niSQENEGLNDDSseas..........................................................................................vvdeDEEDDENGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G4U3C0_PIRID/9-136               ............................................HVAYVLVADFDIDTGSVLSHQYPCP--T...............................GT..DEQTLAE.......SMLPDGVHLTSE.....AWTVFF.LNQTPDSQVVSYG...................-------.-..................................-------EDEQ..................................................................................................SSGSPTREKR.....KDILHVLNLVR.NKADQGVRRGAVVKAIAICTHLPYFQIFKPIMLIALD..............................................................................................................
Q0V5R0_PHANO/110-273             ............................................HVEYILVASFDIDRGSIMEHQYPAAISG...............................--..DETMLAE.......LMLPDQAHMRNQ.....DWTIFF.LHKDTTAEEEEREer...............reR----RRkRrrrkegl...................ddddttagD---------Elegadda....................................................................................eeddydtESEDEPDPDG.....PPLVYVLNLVN.TKLDTTVKRGSIVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G8ZT84_TORDC/13-149              ............................................NILYILTSKFDNKYGPTIVSQYPKHIAGfa..........................qkgAQ..KTIQLAS.......LMIPNNIEHRAAa..gaDCNTFK.LYFNKIDSSYQLL...................PPINEQI.-..................................-----------..................................................................................................----EENSKE.....PSQISFINLVR.AQSDKNDSRGSKIRSIALGTTLSNVEIMKPFLLMALE..............................................................................................................
B0XMM8_ASPFC/81-200              ............................................HVEYILVASFHIDRGPIMEHQYPAPISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSAEGEDEDst...............tpKKKRRKR.Araeqn.......................pndesqDE--------Dtdal..........................................................................................teesSDEEDDGGEG.....PPLMYVLNL--.-------------------------------------p.............................................................................................................
G7X9K5_ASPKW/82-241              ............................................HVEYILVASFHIDRGPIMEHQYPAAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSADADEDDdas.............tgkKKKKKKK.Srigda.......................esgdgdSEDVDGSTEEE..................................................................................................SSDEEEGGEG.....PPLMYVLNLVN.TKQDNSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
F4R6H2_MELLP/60-233              ............................................HAAFVLLAEFDIDTGSGLKHQYPRP--T...............................GT..SEHMLAD.......LMLPDGAHDRTE.....DWTVFF.LNQTPRLTIENDLstskeeilitdpdkpdeseT------.Hlspkkssil................ndpstpnldSKKPDHDDDDD..................................................................................................EKNDDLETNE.....SKLLYVISLVR.TKKDNTVRRGAICKAMAVCSPHPYIQIFKPILLLALE..............................................................................................................
E7L9A4_TRYCR/18-161              ..........................................ay---YVLLAEFDIDTGSCLRVKYPSVNSWveenthvegntlcg..vaegendvsakwfdvLD.lDDDYCAS.......HMLPDGAEKQVV.....SRTIFI.VNRSKPAN-----...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------vdcfpvycftlaestrakeleitciksnaqsewvrhtstgeaflheelhynq..........................................................
A8PX95_MALGO/19-149              ..........................................lc--QFCVLATFHADQGPVLEHSVPVH-TG...............................L-..DEHMLAE.......QMIPDGLHKRDG.....DWTLLI.RRVSELSLPH---...................-VPERPA.H..................................--------VVT..................................................................................................KSPHTEATDA.....GDCIYILSSAR.TIHTADARRGAKLFALAVGTMHPHVSLLKPVLVLALD..............................................................................................................
D4D1A5_TRIVH/91-226              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDNGGPEEDPEfg...............edK---DGD.D.................................eQDEEKNQD--Dls.............................................................................................qeyPEEDDAGS--.....----------A.GMDDEPPLIGAMVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G8BJ22_CANPC/3-125               ............................................NLELILTAEFHIDKGPSLVYQYPHEIPG...............................LQ..NLYFLPE.......LMLPDQIHKRSE.....DYTLFL.LYRNMITGDFQYL...................YNK----.-..................................-----------..................................................................................................------NTCE.....PDPYFLYTIVL.NLHNDEYKRGSQVKSLSIITKIPYFKNFKPVLMICL-d.............................................................................................................
C7GML0_YEAS2/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
F9G8Q1_FUSOF/129-262             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDTSQEEEDEErkv............kenrK------.Qrrkrrrd...................raagiideE---DEENEEDlpedewed..................................................................................ddeddtesTDSEPEGGEG.....PPLIYVLNL--.-------------------------------------p.............................................................................................................
D2W4R6_NAEGR/231-383             ..........................................np---YILETEFDLLKGNTLSHVYPPE--Rr............................tiLN.tFTSHLGD.......YCLPDGAHYFEE.....DATYLV.IPSNVVSSSLYSY..................lKSGASSN.N.................................vSSVSNSENSSV..................................................................................................VNNTQQVMEFiepyvDKPMYAHCLFR.NKKDERVKRGAIQKSIILFSSKPLFTVYENLLRLAL-n.............................................................................................................
G4N038_MAGO7/133-304             ............................................HVEYILVASFDIDRGSVMDQQYPVAITG...............................--..DENMLAE.......LMLPDGAHMRHE.....DWTIFF.LHKDQSEEEEDQEr................qaK---DARkRrrqfrrdk.................alglaggryE---------Gdpgddiened..............................................................................dgygwedddsTDSEADGVEG.....PPLIYVLNLVN.TKLDKTVKRGSIVKAMAICTRHPFLHIYKPLLLLALD..............................................................................................................
Q23F93_TETTS/1-140               ............................................MIDVIFCSEFDLLKGCVVKAHYPE---N...............................FE.yDEITLAA.......YMLPDGVQKFDN.....DISVFK.YKLKQVVDQKTHKlv..............seiN--LNSS.Kel.............................vdlYKFNN------..................................................................................................QKD-------.....-----------.-------------------------------------dweiyqtncsltatnlgdfiifstpeiefgaekqifrfqthkdiqyrklk............................................................
C4R3J0_PICPG/6-134               ...........................................s-LAYILTAEFDKSKGIVITNQHPC---Edd..........................swlLS.sQLQDISN.......VLMPSQLQHSMNr...eSITVFP.IYSTYSDVEFENA...................ILSYDPK.P..................................-----------..................................................................................................---------H.....SLPSVILSISY.FKSDDSYRNG-TANCLSIVTSLSFWYAYKNLLI----vllh..........................................................................................................
Q75BQ9_ASHGO/49-219              ............................................NVEYILAAEFDNKLGPVLKHQFPKNLPGf............................ksTN.sNLSNLAG.......LMIPNGIENRPGe...sDFTTFI.LYKDRYAQTFQLF...................PNDNAKG.Slkptaes...................hghlggspSSRLESMILEEde.............................................................................................nagSSKTSLSQAR.....EIPLFFINVVH.AKIDNANERGAVIKSLAVGTSLQNFFIFKPLLMMALD..............................................................................................................
A7TRE4_VANPO/73-251              ............................................NVHFILSAEFDNKLGPKVKFQYPNSIPGfpssl.....................hgahsLD..STINLAS.......LMIPNNVEYTPGk...kDFTVFM.LYYNTSTKLYQLFkps............niktEVQKNDN.-..................................----DDNDDEEnedgdgddds..............................................................................eyidseiftdAKDENDNLDD.....IDTLYFINVVN.TVIDKNNDRGAVIKSISLGTTLKIFSIFRPVLSKLL-v.............................................................................................................
B8MY96_ASPFN/80-205              ............................................HVEYILVASFHIDRGPIMEHQYPAPISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDSSADQDDDD...................-------.-..................................---------SS..................................................................................................SDDEDEGGEG.....PPLMYVLNLVN.TKQDHTVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G2QD70_THIHA/105-282             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQEEDDAErrak...........eerrA------.Rrrrkrdrekg..............iihesddegdE---------Nggldddddddd............................................................................dddddwdddlsTDSEPESSEG.....PPLVYVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALD..............................................................................................................
F8QFS0_SERL3/7-138               ............................................HCSFVLLAEFDIDSGAQLTYQFPQPLGT...............................--..DEGLLAN.......LMLPDGAERHLE.....DWTIFF.LNQTPFNTIAPVL...................-ALETPE.P..................................----------N..................................................................................................GDKQSRDGSQ.....PELLYVLNLVR.TKHDKSVRRGAVVKAMAICTRHPFIQIFKPVLLLALD..............................................................................................................
F7W328_SORMK/124-292             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDSSREEDEAErqa............keerR------.Rrrkrrldre...............qgiihesddeD-----DD--Lddddwd.....................................................................................ddestddDDDEPEGGEG.....PPLVYVLNLVN.TKHDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
A2Q8P4_ASPNC/82-239              ............................................HVEYILVASFHIDRGPIMEHQYPAAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSADADEDDas...............tgKKKKKKKsRigdae........................sgdgdS---------Edvgg.........................................................................................steeeSSDEEEGGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
E4V050_ARTGP/91-226              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDNGGPEEDPE...................SGEDKDG.D..................................DGQGEEKNQDEls.............................................................................................htyPEEDDAGS--.....----------A.GMDDEPPLIGAMVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
B5VS19_YEAS6/1-133               ...........................................g----------------------------...............................--..-------.......----------KQ.....DITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
A1CRY6_ASPCL/85-243              ............................................HVEYILVASFHIDRGPIMEHQYPAAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSTEEDEDGsa...............atKKKRRK-.Rapadh........................dagddS-------QEEdtdal........................................................................................teessDEDEDDGGEG.....PPLMYVLNLVN.TKQDNTVRRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
I1RRG0_GIBZE/71-241              ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDTSEEDEDKEr................knK---ESRkKrrmrkrdk.................aagvineeeG-----EDEEDlpeeewd...................................................................................ddeeddesSDSEPEGGEG.....PPLIYVLNLVN.TKHDKSVKRGAIVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
Q6CGA4_YARLI/9-124               ............................................HIEYVLAAEFDIDAGPVVKYQYPDTLPG...............................--..DEQLMAE.......LMLPDQSHVRNQ.....DWTIFF.LHDENGLLKYRPN...................-------.-..................................-----------..................................................................................................--------DK.....GDMFYVLNLVN.TKFDKDVRRGAIVKSMCLITRYPYFQIFKPVLILALD..............................................................................................................
F0XQA1_GROCL/147-345             ............................................HVEYILVASFDIDKGPIMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQTHLRNQ.....DWTMFF.LHKDTTPEEEDQErle............karrR------.EkrrrkhghvattdnikttdgtetnglsesdadneE---------Apekdkdaddndnddy....................................................................ddddddddededsmsTDSEPEGGEG.....APLIYVLNLVN.TKQDKTQKRGAVVKSMAICTRHPFLHIYKPLLLLALE..............................................................................................................
H3GE73_PHYRM/13-141              ..........................................la--EVVLYAEFDLTKGSTLRASFPTPFAH...............................Y-..SPEFFAD.......IMLPEGVHNREE.....DVTIFF.LNRQNAYKPAEDQ...................-------.-..................................-------NDAA..................................................................................................VNEKTENDPL.....QSFMYCLSVVR.TTHDSAARRGAKVTAVALCSTHKSCFALKDVLNLA--vl............................................................................................................
F8MMJ6_NEUT8/122-288             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDSSREEDEADrqak...........eerrR------.Rrkrrqdr....................eqgiiheS---------Ddedddldd.................................................................................ddwdddestDEDEPEGGEG.....PPLVYVLNLVN.TKHDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALD..............................................................................................................
D5GKQ5_TUBMM/42-159              ............................................HVEYILVAEFSIDKGPTMEHQYPNAISG...............................--..DEHMLAE.......LMLPDQAHVRFQ.....DWTIFF.LHKDAEQSEDQMD...................-------.-..................................-----------..................................................................................................------PTGH.....APLIYVLNLVN.TKHDKEAKRGAKVKAMAICTRHSFLHIYKPILLLALE..............................................................................................................
G4UQP2_NEUT9/122-288             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDSSREEDEADrqak...........eerrR------.Rrkrrqdr....................eqgiiheS---------Ddedddldd.................................................................................ddwdddestDEDEPEGGEG.....PPLVYVLNLVN.TKHDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALD..............................................................................................................
E9BZT8_CAPO3/13-258              ...........................................l-VHHILVSEFDIDKGSGLAHQYPTP-TG...............................A-..SESLLAE.......LMLPDGVHNREE.....DWTIFF.LNQTAPEHDSAKGsk..............smpS---D--.Nktpavts...................ldafvyefT---------EatqgwsqlgtdtmkvylernalriagpdfskslprdvelqhqsmeplfhcvivgeaafgfrfadqvaeltfethceelrketpsevfeppspapapvvVPSTEKS-SD.....KPFLYVLNVIR.NKRVENVRRGAVVKALAICTPYRWLHVFKPVLLLAV-d.............................................................................................................
H8X3W9_9ASCO/3-125               ............................................NLEFIITAEFHIDKGPSLMYQYPHEIPG...............................LK..SLYFLPE.......LMLPDQIHKRNE.....DYTLFL.LYRNMVTGDFQYL...................YNKNSC-.-..................................-----------..................................................................................................---------E.....PDPYYLYTIVL.NLHNDEYKRGSQVKSLSIITKIPYFKNFKPVLMICL-d.............................................................................................................
E7QKR4_YEASZ/5-83                ................................ikmtknnrytiv----------------------------...............................--..-------.......------------.....------.-------------...................-------.-..................................-LEDDELECQE..................................................................................................VQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
E3QCC1_COLGM/118-260             ............................................HVEYILVASFDIDRGPVMEHQYPVSITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQEEEDEErka.............keaR---K--.Rrrrrlrnra................agiideddgS---------Edlddeevrld..............................................................................dldelddsesDDEEPEGGEG.....PPLIYVLNLVN.TKQDKT-------------------------------p.............................................................................................................
C8ZI91_YEAS8/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
Q7RXB5_NEUCR/122-246             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDSSREEDEAD...................RQAKEERrR..................................RRKRRQDREQGi................................................................................................iHDQERCSGKG.....HGYLH------.-------------------------------------papvssyiqdeyfkapvpetls........................................................................................
Q55YB7_CRYNB/14-162              ...........................................a-VHFCLLAEFDIDAGATLAHQYPYP--T...............................GT..DEHRLAE.......LMLPDGAHLRPE.....DWTIFY.LGQTASSAVDPLL...................SHESEASlQtr.............................tstDSDGKA----Stm..............................................................................................mtSSRAMRGVAG.....GGLLYVLNCVR.MKEDKKMRRGAMVKAMAICTPNPYVGIYKPLLLLALE..............................................................................................................
G0RJ82_HYPJQ/111-286             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTMFF.LHKDSSPEDEDEErka............kaerKA-----.Rrqrrrdraag.............llpedgaegreDE--------Eddrdddddl................................................................................dddltddesSDGEPDGEEG.....APLIYVLNLVN.TKHDKSVKRGAIVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
G8YLF0_PICSO/3-125               ............................................NIEYIITAEFHIDRGPSLIDSFPGSIPG...............................LK..NLPFLPE.......TMIPDQIHKRED.....DYTLFL.LFRDAKTGEFCYM...................KEDKEY-.-..................................-----------..................................................................................................---------E.....EELYYLYTIVF.NSKDDVYRRGSQIKSLSLITRLSFFKSFRPLMTI---cle...........................................................................................................
F2QXF7_PICP7/6-134               ...........................................s-LAYILTAEFDKSKGIVITNQHPC---Edd..........................swlLS.sQLQDISN.......VLMPSQLQHSMNr...eSITVFP.IYSTYSDVEFENA...................ILSYDPK.P..................................-----------..................................................................................................---------H.....SLPSVILSISY.FKSDDSYRNG-TANCLSIVTSLSFWYAYKNLLI----vllh..........................................................................................................
F4PES0_BATDJ/13-193              ...........................................m-AEFVLLAEFDIDKGSSLSCQYPTP-TG...............................A-..DPATLAE.......WMLPEGAHLRRE.....DCSYFI.LNRTKAGTTIPNEsiala........qlqsspL------.-..................................EQECNQR---Nvrvlgridcvfssaddrmy............................................................fmrfvhesaqvlpaqrvfpEDLPEIPTPD.....EPLLYVINMIS.MKIIAGARRSARVKAMAIASRHPWVHPLLIL------aldky.........................................................................................................
B9WE52_CANDC/3-125               ............................................NIEYIVTAEFHIDKGPSIVHQFPNQLPG...............................MD..NLYFLPE.......LMLPDQIHKRNE.....DYTLFL.LHRNTTNGEFQYL...................FNKST--.-..................................-----------..................................................................................................--------CE.....DNPYYLYTIVD.NRKNDEFKRGASIKSLSIITKLSYFKNFKPLLLICL-d.............................................................................................................
D3BKL1_POLPA/333-466             .....aseeeqflqhvnrmikemaeekilaaaaasttisdnnnn----------------------------...............................--..-------.......------------.....------.-----NNSNNNN-...................-------.Ngatdsl.....................nrstsssSSRS------Dsntlat......................................................................................aggspsTTTTTTTSSS.....SQFLYCLNYMN.NQKDESVRRGAIVKSLAICTTHPFIHIYKPFM-----ilgi..........................................................................................................
G0VJ47_NAUCC/27-198              ............................................NVEYIISAEFDNILGPIVKYQYPKTIPGfkfs......................sngelSP.dGPQNIAS.......LMIPNNVEKVPGk...sDFTTFI.LYHNKYTQNYQLFpp..............ptyS----NK.Aseks.........................nvlatV---------Erkrysiv....................................................................................leeeeleSDLTKNKKDD.....LDTLFFFNVVN.TKLDKTNDRGAIIRSLAIGTTLKNYIIFKPILTMTLD..............................................................................................................
G8YNS9_PICSO/3-125               ............................................NIEYIITAEFHIDRGPSLIDSFPGSIPG...............................LK..NLPFLPE.......TMIPDQIHKRED.....DYTLFL.LFRDAKTGEFCYM...................KEDKEY-.-..................................-----------..................................................................................................---------E.....EELYFLYTIVF.NSKDDVYRRGSQIKSLSLITRLSFFKSFRPLMTISL-e.............................................................................................................
I1CGI0_RHIO9/6-109               ............................................HVEYILLAEFDIDKGASLKHQHPTE-TG...............................T-..DEHILSE.......LMLPDGAHLRAE.....DWTIFC.LNQLTPDPDQQQI...................-------.-..................................-----------..................................................................................................-------V--.....-----------.DEEHKSPLLGARVKAMAICTRHQYLHIYKPVLLLAM-e.............................................................................................................
D2V9C8_NAEGR/7-162               ........................................nlls----ISIAEFDKLSGNSLTHTYPTDVHL..............................eKY.yPTSNIAD.......KCIPDGAHIYHE.....DQTGII.LPITEDNTELIQVlhky...........issfKFTTSPT.-..................................----------Ppkpips......................................................................................spssniPNNNDNGFQN.....SQYLYGSVFFR.NKLDDRVRRGAIQKSILVVTTKPLFTLFIPLMRD---aid...........................................................................................................
G3B9I0_CANTC/3-124               ............................................NIEFIVTAEFHVDKGPSLLHQIPVSLPG...............................LA..NLVFLPE.......LMIPDQIHKRSE.....DYTLFL.LYRNSSTGEFQYL...................S------.-..................................-----------..................................................................................................-----DAKCE.....PDPYFLYTLVM.NVKDESVKRGSVIKALAIITKLRYFKNFKPLLMIALD..............................................................................................................
A8N5K3_COPC7/7-144               ............................................HCSFVLLAEFHILEGAQLKYQFPQPLGV...............................--..DESILAM.......SMLPDGAEAQLD.....DWTIFF.LNQTPFNTISPVLa.................lDTPETR-.-..................................----------Sid.............................................................................................lpvEGADGGQGKK.....QDLLCVLNLVR.TKHDKTLDRGAKVMALAICTRHPFIQIFKPLLLMALD..............................................................................................................
H0GNP3_9SACH/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
E9F477_METAR/111-276             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDTSQEEEDAErqv............kerkR------.Qmrrrrrnraag............viseddeeefdD---------Edddde.......................................................................................dvddesTDSEPEGGEG.....PPLIHVLNLVN.TKHDKSVKRGAVVKAMAICTRHPFLHIYK--------vsratt........................................................................................................
Q0CUX1_ASPTN/72-232              ............................................HVEYILVASFHIDRGPIMEHQYPAPISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSGEDEDDEsv...............rgKKKKKKR.Aevssdge....................dpegnpeD---------Ddgeg.........................................................................................lseesSDDEDEGGEG.....PPLMYVLNLVN.TKQDNTVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
Q4WKC8_ASPFU/81-200              ............................................HVEYILVASFHIDRGPIMEHQYPAPISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSAEGEDEDst...............taKKKRRK-.Raraeqn......................pndesqDE--------Dtdal..........................................................................................teesSDEEDDGGEG.....PPLMYVLNL--.-------------------------------------p.............................................................................................................
G8BYZ7_TETPH/47-206              ..........................................na--CFILSAQFDNKLGPVIRHQYPKCIPGfknhl.....................cgtsdSD..ESINLAS.......LMIPNNVELTPGk...kDYTMFS.LYYNNNTDKYELF...................KPTSDTL.-..................................-NDNNYNTIREvd.............................................................................................efeDAQEHHESNH.....IDVLYILNIVN.TIIDKTNSRGAVIKSIALVTPNKIGSIFRPLLSKVLD..............................................................................................................
A0C6F7_PARTE/1-181               ............................................MIKALFAAEF-LVKGCVITASYPQ--TG...............................-D.sGFHELAS.......YMIPDGVHKIKQ.....DKFFFR.IGNVRFVSGQVQTyhfdy.........qwkplL--QSSN.Qt...............................lsYSDDNVLKIRGekesewldinlsn........................................................................aqihvishdfvsiTLNPDLIYGIk..gkFTQDYYLACLR.NKKDATIKRGSLIRSIAVCSSDLLFLGICD-------qkiqkc........................................................................................................
E2L8K6_MONPE/5-62                .........................................pge----------------------------...............................--..-------.......------------.....------.-------------...................-------.-..................................-----------..................................................................................................---EEHPAGK.....PDLLCVLNLVR.TKHDKTLDRGARVLALAICTRHPFIQIFKPVLLMALD..............................................................................................................
E7Q9P2_YEASB/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQXAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
Q55D43_DICDI/112-257             ...........................................l-VEFILLAEFDILQGSKVKYQYPYPIAT...............................GE..MELMLSE.......YMLPDGAHKRND.....DWTVFF.LNRPVPEGGALTAsk..............speK---SK-.N..................................NNNNNNNNNNN..................................................................................................NNNNNNNNNS.....SSSSSPSSPNNqNNKSPQIDSKSSE-KQISSPVEAFIYSFSETDE----ekgw..........................................................................................................
Q6CPS0_KLULA/28-197              ............................................NVQFIIAAEFDNKSGPIIKHQYPKTIPGfk..........................tigSD.sTCSHLAS.......LMIPNSVENHPGk...pDFTVFV.LYKNQNV--YQLF...................PVSKNKTkGtdld..........................ssliI--------EEedfeeeqen................................................................................glrsgkigsIRDDRHLEET.....EPPLFFLSVVN.TFLDNSNDRGAYIKAIALGTTMTNFYTFKPLLTMVLD..............................................................................................................
D3BKL1_POLPA/154-252             ............................................NVEYILLAEFDIDIGSKVKYQYPCP--T...............................GE..DEALLAE.......FMLPDGAHNRDA.....DWTVFF.LNRPDPDGILSKN...................KKAKPK-.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------pktqgkiictieafiykfseeqeskgw...................................................................................
AFI1_YEAST/26-218                ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQKAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
A6RVU6_BOTFB/70-232              ............................................HVEYILVASFDIDKGPIMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQDEEEAE...................EKAERRRlRkakke.......................araalfE---------Sgnvdpler.................................................................................vegseedssEEDEPEGGEG.....PPLIYVLNLVN.TKQDKTAKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
D7G403_ECTSI/14-161              ..........................................ls----------------TVRHAYPSSVPG...............................V-..SDDWFAE.......HMLPEGAHNHAL.....DWTVMF.LNRDKTALDEDWPayfdcd.......epagsaE--KG--.Rssagg........................idavgD---------Ksyep.........................................................................................rlargGEGEGEGEEG.....RSFLHCINLVR.KQDDPTVRRGAVVKAMCICSRYNYIEVFRPMLMIALE..............................................................................................................
C9SV70_VERA1/118-292             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQEEEDEErkr............kerrR------.Krrrrrqnea................agildeedeD----GEEDEEdeeeeddd.................................................................................lddfdddesTDSEPEGGEG.....PPLIHVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
B9RE36_RICCO/27-178              ......................................vafcai--------RFDLEQGQLIEECYPPGILS...............................NE..EELDVAF.......SSFPDSVSQQQNrssihDCIFFFrIRRRKGSEEKNVTts...............eiI-----EvD..................................SNEVSSKSIEEkv..............................................................................................tqRSNSGKNDKN.....FKFLYGYVFNR.QRHDERLKRGGEQKSVVILSHDPYSSVFRPLL-----qimg..........................................................................................................
C6HAC6_AJECH/90-246              ............................................HVEYILVASFHVDRGPMMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGTEEENEYveps..........agqhaE---NNI.Nsqen..........................gglnDD--------Gsevs..........................................................................................eadeGEDDEGNAEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
C5P112_COCP7/90-249              ............................................HVEYILVASFHVDRGPIMEHQYPAAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTMFF.LHRDAGSEDENEYgddsqg......qaekavdE------.Akedsq........................dghdqTEDEEATDDDG..................................................................................................DDDDEEAGDG.....PPLMYVLNLVN.TKQDNSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
D2VQ16_NAEGR/2-155               .........................................dif---CVCIAEFDLLKGNTLSHVYPPE--Rr............................tiLN.tFTSHLGD.......YCLPDGAHYFEE.....DATYLV.IPSNVVSSSLYSY..................lKSGASSN.N.................................vSSVSNSENSSV..................................................................................................VNNTQQVMEFiepyvDKPMYAHCLFR.NKKDERVKRGAIQKSIILFSSKPLFTVYENLLRLAL-n.............................................................................................................
D4AJX3_ARTBC/91-226              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDNGGPEEDPEfg...............edK---DGD.D.................................eQDEEKSR---Dd...............................................................................................lsQEYPEEDDAG.....---------SA.GMDDEPPLIGAMVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
C4Y911_CLAL4/3-125               ............................................NISFIVTAEFHVDKGPSLIHQYPNVLPG...............................SE..GLQYLPE.......LMLPDQIHKRPE.....DYTLFL.LYVNSLTGKLQYQ...................YDS----.-..................................-----------..................................................................................................-----K-TCD.....SKPFFVYTIVN.NVPDQNVKRGSIIKSLSIVTRLKYFKHFKPLLMICL-d.............................................................................................................
E3RFI2_PYRTT/104-276             ............................................HVEYILVASFDIDRGSIMEHQYPTAISG...............................--..DETRLAE.......LMLPDQAHVRSQ.....DWTIFF.LHKDTTAEEEEREar...............reR----RRrRrrrk.........................egledE---------Ddgdaaaaagaqdpd.....................................................................hddddfydedgdedtESESEPDPDG.....PPLVYVLNLVN.TKQDNTVKRGAIVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
Q4D5Z4_TRYCC/14-147              ..........................................ay---YVLLAEFDIDTGSCLRVKYPSVTSRveesthvegntlcg..vaeggndvltkwfdvLG.lDDDYCAG.......HMLPDGAEKQVV.....SRTIFI.LNRSKPAN-----...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------vdcfpvycftlagstrakeleitclksnaqsewvrhtstgea....................................................................
B2WB45_PYRTR/51-218              ............................................HVEYILVASFDIDRGSIMEHQYPTAISG...............................--..DETMLAE.......LMLPDQAHVRSQ.....DWTIFF.LHKDTTAEEEEREar...............reR----RRrRrrrk.........................egledE---------Ddaaagaedaeld..........................................................................ndfdgedgdedtESESEPDPDG.....PPLVYVLNLVN.TKQDNTVKRGAIVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
D4AU15_ARTBC/28-126              ..........................................ac----------------------------...............................--..-------.......------------.....---VFL.AKRDETKEKDRKK...................QRKRRREeKak..............................kgQRDRRERNREH..................................................................................................RQQQQHQQQQ.....QESKQESKPAS.KQAAEEKRENPAKAALPRLTYLNVLAVLR--------lshrlvl.......................................................................................................
E4ZT50_LEPMJ/111-279             ............................................HVEYILVASFDIDRGSIMEHQYPAAISG...............................--..DETMLAE.......LMLPDQAHVRSQ.....DWTIFF.LHKDTTAEEEEREarr.............errR-----R.Rrrrkegl...................ededasagAQENDNDHDEEvdgdd........................................................................................ldnesETDEEQDPDG.....PPLVYVLNLVN.TKQDNTVKRGAIVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G1XGV3_ARTOA/66-156              ............................................HVDYILVAEFSIDKGPTMEYQYPAPISG...............................--..DEHMLAE.......LMLPDQTHRRNQ.....DWTVFF.LHKEEEETED---...................-------.-..................................-----------..................................................................................................------DPGQ.....QPLIYVLNLVN.TKRDNRIKRH---------------------------etf...........................................................................................................
D8QBP3_SCHCM/7-137               ............................................HCSFVLLAEFHLLEGAQLKYQFPQPLGI...............................--..DEGVLAM.......SMLPDGAETQLD.....DWTVFF.LNQTPFNTIQPVL...................ALDD---.-..................................--------ADT..................................................................................................SVRSSVVGDQ.....PDLLCVLNLVR.TKHDKTWERGAKVLALAICTRHPFIQIFKPVLLMALD..............................................................................................................
C7YNT7_NECH7/126-297             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDTSQEEEDEErka............keerK------.Rrrkrrrdrlagii........deededaeddlleD---------Dwddeed.....................................................................................dddddssTDSEPEGGEG.....PPLIYVLNLVN.TKHDKSVKRGAIVKAMAICTRHPFLHIYKA-------tvivi.........................................................................................................
F0ULC4_AJEC8/90-246              ............................................HVEYILVASFHVDRGPMMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGTEEENEYveps..........agqhaE---NNI.Nsqen..........................gglnDD--------Gsevs..........................................................................................eadeGEDDEGNAEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G2YRD1_BOTF4/130-292             ............................................HVEYILVASFDIDKGPIMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQDEEEAE...................EKAERRRlRkakke.......................araalfE---------Sgnvdpler.................................................................................vegseedssEEDEPEGGEG.....PPLIYVLNLVN.TKQDKTAKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
F9WZ87_MYCGM/85-247              ............................................HVEYILVASFDIDRGSIMEHQYPSPVGG...............................--..DESMLAE.......LMLPDQAHVRSQ.....DWTIFF.LHKDAGVEDEDQEsgrr...........rrgrR------.Rkleeqgdd.................aeagagtetE---------Edeesd........................................................................................fddedESEDEMSLDG.....PPLVYVLNLVN.TKQDNTVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
I1BNQ9_RHIO9/4-119               ............................................HVEYILLAEFDIDKGASLKYQYPA---G...............................TG.tDEHVLSE.......LMLPDGAHLRAE.....DWTIFC.LNQLTPDPEQEVE...................-------.-..................................-----------..................................................................................................--------QK.....SPLLYVLNLVR.TKHDATARRGARVKAMAICTRHQYLHIYKPVLLLAM-e.............................................................................................................
F4QE10_DICFS/103-353             ............................................NVEYILLAEFDIDIGSKVKYQYPCP--T...............................GE..DESLLAE.......FMLPDGAHKRDD.....DWTVFF.LNRPDPDGHLSKN...................KKKETTP.Kpekplc.....................nsieafiYKFSEDEESKGwvmldpdklnlqiyrntinvmgkngslvtkiekhidlehtqleplfdc..vltdsgtalgvrffeqqdednflshinrmvkeiteertiiesskkggdGAEINED--Tk...cKDFLYCLNFMN.NQKDESVRRGAVVKSLAICTTHPFIHIYKPFM-----ilgi..........................................................................................................
B8MHD8_TALSN/85-247              ............................................HVEYILVASFHIDRGPIMEHQYPSAISG...............................--..DEGMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTESDDEDAEres............pkrrR-RR---.Rrkqqte.....................ieqesdaD----SNNDEDdqsd..........................................................................................aaesTDDEEDSGEG.....PPLMYVLNLVN.TKQDNTVRRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
A6ZNX6_YEAS7/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQKAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
Q5KLM3_CRYNJ/14-162              ...........................................a-VHFCLLAEFDIDAGATLAHQYPYP--T...............................GT..DEHRLAE.......LMLPDGAHLRPE.....DWTIFY.LGQTASSAVDPLL...................SHESEASlQtr.............................tstDSDGKA----Stm..............................................................................................mtSSRAMRGVAG.....GGLLYVLNCVR.MKEDKKMRRGAMVKAMAICTPNPYVGIYKPLLLLALE..............................................................................................................
Q2H6V1_CHAGB/196-367             ............................................HVEYILVASFDIDRGPVMEHQYPVSITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSHEEDEAErq...............akE----ER.Rarrirr.....................rdrakgiIHESDEEDEEEgdlddldd..................................................................................ddwdddesTDEEQDGFEG.....PPLVYVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
G2R9J9_THITE/121-291             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTTQEEEDAErra............reerR------.Arrnrkr......................drakgiIHESDDEDEEGgglgddd...................................................................................ddwdddvsTDTEPEIGEG.....PPLVYVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPILLLALE..............................................................................................................
Q55D43_DICDI/384-492             ....................ntntntntnttttttttttattte----------------------------...............................--..-------.......------------.....------.--------NI---...................-------.Qptnttt.....................tegenntTKDSKDSKDPS..................................................................................................ISETPEDQKC.....KDFLYCLSFMN.NQKDDTVKRGAVVKSMAICTTHPFISIFKPFIVLAM-q.............................................................................................................
G0UNX7_TRYCI/13-123              ..........................................fl--HQLLLAEFDIDIGSCIRVRYPQDLTSsyiyqrdsagvg......dvdeavssqrkiiQE..DDTVFAN.......YMMPDGSEKHVV.....GRTVFI.VSR----------...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------pipvvtasfslycfslvessteapddsa..................................................................................
B0D0E4_LACBS/6-143               ............................................HCSFVLLAEFHIFEGAQLKYQFPQPLGI...............................--..DESVLAM.......SMLPDGAETQLD.....DWTIFF.LNQTPFNTISPVL...................-ALDTPEvSpv.............................glpG----------..................................................................................................GEVNGVKNDK.....PELLCVLNLVR.TKHDKSLDRGAKVLALAICTRHPFIQIFKPFLLMALD..............................................................................................................
Q6BI40_DEBHA/9-132               ............................................NIEYIITAEFHIDQGSSLIHQVPREIPG...............................LQ.tNLTFLPE.......IMIPDQIHKREE.....DFTLFL.LFKDRETGDFQYL...................Y------.-..................................-----------..................................................................................................----DKTTCD.....EEPYYLYTIVN.SLKHDSYERGSRVKSISIITKLPYFKNFRPLLTLC--ln............................................................................................................
A4I5V0_LEIIN/15-145              .........................................ats----VIVAEFDIDTGACLRACYPP-VPTspstallss............iesgappgiaG-..HTEYFAN.......VMLPDGAEKVNV.....TRTVFV.VNRPQPP------...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------lylrfpvyrfarasastgssdtqaawerrpgeetaryvpeillinatteevsl.........................................................
C5JQA6_AJEDS/90-246              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGSEEENEYvep............tagqQ----T-.Eyn..............................niSQENEGLNDDSseas..........................................................................................vvdeDEEDDENGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
Q4P9F2_USTMA/25-158              ..........................................ct---FCMLAEFDIDRGSTLSHQYPAPTG-...............................-Y..DEHMLAE.......LMLPDGVHARTE.....DWTFFF.LKPPGTERAALQN...................SVDDP--.-..................................-----DSSQLG..................................................................................................AATDPTAWLS.....HDLTYVINLVR.TKHDNTVRRGAMVKAIAIGTRYPFIEIFKPALLLALD..............................................................................................................
C5GBC1_AJEDR/90-246              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGSEEENEYvep............tagqQ----T-.Eyn..............................niSQENEGLNDDSseas..........................................................................................vvdeDEEDDENGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G0SZG0_RHOG2/29-170              ............................................HVEYVLLAEFDIDQGSVLRHQYPCP--T...............................GT..DEHLLAE.......HMLPDGAHDRPE.....DWTVFY.LGQIPPLTVDRAL...................LAKTRADlK..................................GKG--KAVEGD..................................................................................................EADIGEEEED.....NGLLYVMSLVR.TKKDASVRRGALVKALAVVTRNPYIQIFKPALLFALE..............................................................................................................
C5FTF7_ARTOC/91-227              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDSGGPEDDAEf................geD--KDT-.-..................................DDEQDGDKQQDdvsq.........................................................................................eyageEDAGSAGID-.....-----------.--DEPPLISGATVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
F0ZTU4_DICPU/309-438             eiqddqakgktksesspeittdntspqqpvnsnpnettttttat----------------------------...............................--..-------.......------------.....------.------------Epst.............ttnPTENKDS.S..................................SKD-------Tpasn.........................................................................................esttnPNEPPEDQKC.....KDFLYCLNYMN.NQKDDTAKRGAVVKSMAICSTHPFINIFKPFIVLAM-q.............................................................................................................
C4JVY8_UNCRE/89-247              ............................................HVEYILVASFHVDRGPIMEHQYPAAISG...............................--..DENMLAE.......LMLPDQTHVRSQ.....DWTMFF.LHRDTGSEDGIEDggdp..........qdqeeK------.Agdepee.....................ngqdgarQTDD------Edsa............................................................................................dddGYEDEDCGDG.....PPLMYVLNLVN.TKQDNSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
C0NC17_AJECG/90-246              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGTEEENEYveps..........agqhaE---NNI.Nsqen..........................gglnDDGSEVSEADE..................................................................................................GEDDEDNAEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
D2VRW9_NAEGR/60-245              ...........................................g-IEYIFLAEFDIDKGSIVKVQYPSPYPY...............................A-..TEYSIAN.......LMLPDGSHNCIE.....DTTVFF.LRGNNEINNNHHN...................ENNTSAS.Slnnsn........................sgnnnS---------Silsngsndggeeakssprn............................................................sqevvekvdlntslestilSSDQVITEQSk..keEIFYYVLNVQK.QKKYEGLRRAARVKSLAIVSKHPYCFSLRDLLSKALD..............................................................................................................
A7EPQ6_SCLS1/130-292             ............................................HVEYILVASFDIDKGPIMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQDEDEAE...................EKVKRKRlRrakkearaa...............lfesgnvdplGPVEDSDEDSS..................................................................................................EDDEPEGGEG.....PPLIYVLNLVN.TKQDKTAKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
E6QZ55_CRYGW/14-161              ...........................................a-VHFCLLAEFDIDAGATLAHQYPYP--T...............................GT..DEHRLAE.......LMLPDGAHLRPE.....DWTVFY.LGQTASSAVAPLLs................heSETL---.Qtr.............................tstDSDGEAST--Mv................................................................................................tSSRATRGVAG.....GGLLYVLNCVR.MKEDKKMRRGAMVKAMAICTPNPYIGIYKPLLLLALE..............................................................................................................
C1GKI9_PARBD/91-250              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DENMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGSEEEQECgds............svdqQ----AG.Ns...............................riRQENEGLN--Dggsevs.....................................................................................vgdedeiEDEDEENGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
A3GHI4_PICST/3-125               ............................................NIDYIVTAEFHIDKGPSLIYQHPSELPG...............................LS..NLYFLPE.......LMLPDQIHKRED.....DYTLFM.LYRNTYTGEFQYL...................FNRKNC-.-..................................-----------..................................................................................................---------E.....PEPYFLYTIVS.NVKDTSFKRGSIIKSLSIITRLHYFKNLRPLMLICL-d.............................................................................................................
H0H162_9SACH/26-219              ............................................NVSYIISAEFHNKLGPIVKHQYPKNIPGfkqsl....................hgehndNT.sVSMNLAN.......LMIPSSIERNPGk...qDITVFT.LYCNKFTQNYQLF...................PVPKDPRfNfnlhhrdqp...............dsnvgnsihfD---------Aennhnvqnnryt.........................................................................ivlddddelesqeVQDNQKVSD-.....DEPLFFINVAN.TILDATNDRGAVIKSIAIGTPLKTFFVFKNILVLVLD..............................................................................................................
H1V9B3_COLHI/118-291             ............................................HVEYILVASFDIDRGPVMEHQYPVSITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQEEEDEErka.............kevRKKRR--.Rrlrnraagi...............ideeddgenlD---------Ddeegeldd.................................................................................ldenddsesDDGEPEGGEG.....PPLIYVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALD..............................................................................................................
E9EBE0_METAQ/111-275             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDSSQEEEDAErqa............rerrR------.Qirrrrrnraag............visedeeefddE---------Dddded........................................................................................vddesTDSEPEGGEG.....PPLIYVLNLVN.TKHDKSVKRGAIVKAMAICTRHPFLHIYK--------vsratt........................................................................................................
G3J5M9_CORMM/112-284             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTIFF.LHKDMTDEEEDEErkr............kerrR------.Rrrrkrralaagi.........vpssqddetqdsdD---------Eyddadd.....................................................................................dddddddSDTEPEGGEG.....PPLIYVLNLVN.TKHDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
Q2URL2_ASPOR/80-239              ............................................HVEYILVASFHIDRGPIMEHQYPAPISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDSSADQDDDDsv..............gakK-KKKKS.Kashggd.....................gtggsdeDQDESGKEEES..................................................................................................SDDEDEGGEG.....PPLMYVLNLVN.TKQDHTVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
C0SET4_PARBP/168-288             ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DENMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGSEEEQECgds............svdqQ----AG.Ns...............................riRQENEGLN--Dggsevs.....................................................................................vgdedeiEDEDEENGEG.....PPLIYI-----.-------------------------------------gka...........................................................................................................
D0MTX1_PHYIT/14-147              ..........................................la--EVALYAEFDLTKGSTLRASYPSPFAH...............................Y-..SPEFFAD.......IMLPEGVHNREE.....DFTIFF.LNRQNAHKSINTD...................-------.-..................................---EKDSNESQ..................................................................................................TRTADEIQDP....lQSFMYCLSVVR.TTHDTAARRGAKVTAVALCSTHKSCFALKDVLNLA--vl............................................................................................................
C5DZH0_ZYGRC/8-142               ............................................NVDYLLTAEFDNRFGPVVRDQYPSVIPGfeyem.....................reghsQN.nAVFNLAS.......LMIPNNAEYNTGd..epDTTVFM.LYRNRETVKYELF...................PSKQVD-.-..................................-----------..................................................................................................----------.....-QVICFVNVVY.AQEDKSNSRGTNIKAVALGTTMVDFIAFKPFVLEC--lh............................................................................................................
C5M7V5_CANTT/3-125               ............................................NIEYIVTAEFHIDKGPSLVYQYPSNLPG...............................LE..KLYFLPE.......LMLPDQIHKRSE.....DYTLFL.LHRNTHNGEFQYL...................Y------.-..................................-----------..................................................................................................----DKSCCE.....EDPYYLYTIVN.NQKNDEFKRGSRIKSISIITKLPYFKNFKPLLLICL-d.............................................................................................................
F2PTM1_TRIEC/91-226              ............................................HVEYILVASFDVDRGPIMEHQYPSAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDNGGPEEDPEfg...............edK---DGD.D.................................eQDEEKNQD--Dls.............................................................................................qeyPEEDDAGS--.....----------A.GMDDEPPLIGATVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
F0ZTU4_DICPU/95-230              ...........................................l-VEFILLAEFDILQGSKVNIQYPYPIAT...............................GG..MELMLSE.......WMLPDGAHKRND.....DWTVFF.LNRPVPENIKSPE...................KSKSSSS.K..................................SSQ--------..................................................................................................-SPQSPSKID.....TNNNNNNNNNN.NNNNKSATAAPKVEKQISSPLMAYIYSFSETDEE---kgw...........................................................................................................
MESA_EMENI/79-241                ............................................HVEFILVASFHIDRGPIMEHQYPGPISS...............................--..DEGMLAE.......LMLPDQTHVRSQ.....DWTIFF.LPLDTGGEGEEDDlage..........nnkrkG------.Krnrvrsss.................gdegtsadtNNESEVTEEEE..................................................................................................SSDEEDGGEG.....PPLMYVLNLVN.TKQDNTVKRGAVVKAMAICTRHSFLHIYKPILLLALE..............................................................................................................
A1D4W9_NEOFI/81-208              ............................................HVEYILVASFHIDRGPIMEHQYPAPISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSAEGEDEDst...............taKKKRRK-.Raraeq........................npdeeSQD-------Edtda.........................................................................................lteesSDEEDDGGEG.....PPLMYVLNLVN.TKQDNT-------------------------------p.............................................................................................................
F8NI12_SERL9/7-138               ............................................HCSFVLLAEFDIDSGAQLTYQFPQPLGT...............................--..DEGLLAN.......LMLPDGAERHLE.....DWTIFF.LNQTPFNTIAPVL...................-ALETPE.P..................................----------N..................................................................................................GDKQSRDGSQ.....PELLYVLNLVR.TKHDKSVRRGAVVKAMAICTRHPFIQIFKPVLLLALD..............................................................................................................
G7E913_MIXOS/3-139               ............................................HVAYVLAAEFDIDEGATLRHQIPCE-TG...............................T-..DASLLAE.......LMLPEGVHNRTE.....DWTIFY.LNQNPALSVRS--...................PVPESNGfT..................................TSR-----ANG..................................................................................................AAQANEAVKS.....DKVLYVISLVK.VKKDDTVRRGGITKAVAICTYHPFIQIYKPILLLALE..............................................................................................................
B6QMP6_PENMQ/85-245              ............................................HVEYILVASFHIDRGPIMEHQYPAAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTESDDEDAGe................tsK---RRRrRkrqq.........................teteqG------SDEElandedl....................................................................................qsdepdsTDDEEDSGEG.....PPLMYVLNLVN.TKQDNTARRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G2X7J5_VERDV/118-292             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDTSQEEEDEErkr............kerrR------.Krrrrrhneaa..............gildeededgE------GDEEddeeeddd.................................................................................lddfdddesTDSEPEGGEG.....PPLIHVLNLVN.TKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALE..............................................................................................................
H6C574_EXODN/42-200              ............................................HVEYILVASFDIDRGPIMEHQYPGAISP...............................--..DENMLAE.......LMLPDQTHVRQQ.....DWTMFF.LHKDTGSSEEEAAeke.............arvK-----R.Rtarrh.......................areaaqA---A-----Nlkgeef......................................................................................edetssDESDAAGSDS.....PPLMYVLNLVN.TKQDSSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
B6HSJ1_PENCW/75-232              ............................................HVEYILVASFHIDRGPIMEHQYPAAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTMFF.LHKDTSGDEETDSa................dgKKKKKRKsQ.................................yHGNQAGADIQDeyldd........................................................................................isddpDSSDDEGGEG.....PPLMYVLNLVN.TKQDNTVRRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
G9ND52_HYPVG/110-287             ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTMFF.LHKDSSPEDEDEErkq............karrK------.Arrqrrrdkaagl.........vpedgaeggageeD---------Ededdegddd...............................................................................ldedldddesSDDEPDGLEG.....PPLIYVLNLVN.TKHDKTVKRGAIVKAMAICTRHPFLHIYKTLSML---yd............................................................................................................
F0VZ52_9STRA/41-164              ..........................................la--QVVLYAEFDIDKGSTLRESYPYAIDH...............................Y-..SPEFFAD.......LMLPEGIHNRED.....DFTVFF.LNRKTCLDSECI-...................-------.-..................................-----------..................................................................................................SSDKDDIKPV.....REFMYCQSVVR.TTHDNMVRRGASVKAVAICSRYKWCFSLRQLLDL---avr...........................................................................................................
G3XSB1_ASPNA/82-239              ............................................HVEYILVASFHIDRGPIMEHQYPAAISG...............................--..DESMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDTSADADEDDas...............tgKKKKKKKsRigdae........................sgdgdS---------Edvgg.........................................................................................steeeSSDEEEGGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
B3LJH1_YEAS1/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
G9P6A1_HYPAI/70-237              ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DENMLAE.......LMLPDQAHARNQ.....DWTMFF.LHKDSSPEDEDDErka............karrR------.Arrqrrrdkeaglv.......pegeteseedsegsE---------Ddlde.........................................................................................dddesSDDEPDGAEG.....PPLIYVLNLVN.TKHDKTVKRGAIVKAMAICTRHPFLHIYKE-------yyks..........................................................................................................
G0SHI3_CHATD/69-213              ............................................HVEYILVASFDIDRGPVMEHQYPVAITG...............................--..DEHMLAE.......LMLPDQAHVRNQ.....DWTIFF.LHKDPSQEEEEAErra............reerR------.Arrarrr.....................drakgiiH---------Esddeadgtg...............................................................................lddddwdddsSDSEPEINEG.....PPLIYVLNLVN.TKQDKTVKRGA--------------------------ipll..........................................................................................................
E7A2F3_SPORE/27-156              ..........................................ct---FCMLAEFDIDRGSTLSHQYPAPTG-...............................-Y..DEHTLAE.......LMLPDGVHARTE.....DWTFFF.LKPPGFQRAAPHD...................AAEHADT.-..................................-----------..................................................................................................SPADASSWLS.....HDLTYVINLVR.TKHDTTVRRGAMVKAMAIGTRFPFIDIFKPALLLALD..............................................................................................................
A5DM71_PICGU/25-147              ............................................NIEYLLTAEFHVDKGPTLVYQHPSPLPG...............................ID..NLAFLPE.......LMLPDQIHKRSE.....DYTLFL.LHRNTSTGEFQYL...................-------.-..................................-----------..................................................................................................---NDRAVCE.....PEPYYLYTIVN.NVSDDQTRRGSIIKSISIITKLTFFKNFKPLLMICL-d.............................................................................................................
C5DJD2_LACTC/29-192              ............................................NAQYIISAEFDNKVGPVIKHQHPKPLAGfk..........................sstSR.sASVNLAS.......LMIPNSAESRPDv...aDFTVFI.LYKDKYTRNYHVF...................PIADSKL.P..................................QNDARSPTILEedepq.......................................................................................sglageASTNHNADTK.....EPPLFFLSVVN.ALHDKSNDRGATIKSIALGTTMQNFIIFKPLLAMTLD..............................................................................................................
Q4DMT0_TRYCC/18-158              ..........................................ay---YVLLAEFDIDTGSCLRVKYPSVTSRveenthvegntlcgvaegendvlakwfdvlgL-..DDEYCAS.......HMLPDGAEKQVV.....SRTIFI.VNRSKPAN-----...................-------.-..................................-----------..................................................................................................----------.....-----------.-------------------------------------vdclpvycftlagstrakeleitclksdaqsewvrhtstgeaflheelh.............................................................
E7M0D3_YEASV/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQNAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
A6R562_AJECN/90-245              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DEHMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGTEEENEYveps...........agqhA--ENNI.Nsqe...........................ngglNDD-------Gsev...........................................................................................seadEGEDEDNAEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
C4YQL5_CANAW/3-125               ............................................NIEYIVTAEFHIDKGPSIVHQFPNQLPG...............................MD..NLYFLPE.......LMLPDQIHKRNE.....DYTLFL.LHRNTTNGEFQYL...................FNKST--.-..................................-----------..................................................................................................--------CE.....DNPYYLYTIVD.NRKNDEFKRGASIKSLSIITKLSYFKNFKPLLLICL-d.............................................................................................................
A5DZ96_LODEL/3-125               ............................................NLEYILTAEFHIDKGPSLTYQYPNEIPG...............................LQ..NLYFLPE.......LMLPDQIHKRNE.....DFTLFL.LYRNLNTGEFQYL...................YNR----.-..................................-----------..................................................................................................-----NTCE-.....SEPYFLYTIVT.NMKKDEFKRGSQIKSLSVLTKLSFFKSFKPLLMICL-d.............................................................................................................
G2WN04_YEASK/26-218              ............................................NVSYIISAEFDNKLGPILKHQYPKDIPGfnqfs....................heqrngNT.sVSMNLAS.......LMIPSSIERNPGk...qDITVFT.LYYNKFTQNYQLF...................PVPKDPRfSfnlhhreqs................dgsvtnsiyYDAENHQDAKNnrytivle..................................................................................ddelecqeVQNNQKAIDN.....-EPLFFINVAN.TVLDTTNDRGAVIKSIAIGTPLKTFFAFKNIIVLVLD..............................................................................................................
Q5ANI4_CANAL/3-125               ............................................NIEYIVTAEFHIDKGPSIVHQFPNQLPG...............................MD..NLYFLPE.......LMLPDQIHKRNE.....DYTLFL.LHRNTTNGEFQYL...................FNKST--.-..................................-----------..................................................................................................--------CE.....DNPYYLYTIVD.NRKNDEFKRGASIKSLSIITKLSYFKNFKPLLLICL-d.............................................................................................................
G0W7P9_NAUDC/32-217              ............................................NIEFILSAVFDNRLGPTIKYQYPKSIPGfkypssssl.............lspgspnnsSNpdEPLNLAN.......LMLPNNVEKTPGk...aDFTVFI.LYHNKITQTYQLF...................PPSSKKIkNav..............................vhSSANNTPKYDKlkrysil....................................................................................veddetaDKVDALKTTA.....EAPLFFINVVN.TVLDETNDRGAIIKSLAVGTTLKNFNIFKPLLLMTL-h.............................................................................................................
C1H4C3_PARBA/91-250              ............................................HVEYILVASFHVDRGPIMEHQYPSAISG...............................--..DENMLAE.......LMLPDQTHVRSQ.....DWTIFF.LHKDAGSEEEQECgds............svdqQ----AA.Ns...............................riRQENEGLNDGGsevsv.......................................................................................gdedevEDEDEENGEG.....PPLMYVLNLVN.TKQDTSVKRGAVVKAMAICTRHSFLHIYKPLLLLALE..............................................................................................................
#=GC seq_cons                    ............................................pVEYILlApFDlD+GPhhcHQYPssIsG...................................DEphLAE.......LMLPDpsHhRsp.....DWTlFa.La+sssspptp.............................t............................................p..................................................................................................sppptpsscs.....sshhYllNlVs.sppDpos+RGAhlKuhAIsTphsahplaKPlLllsL...............................................................................................................
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