GenomeNet

Database: Pfam
Entry: Alveol-reg_P311
LinkDB: Alveol-reg_P311
Original site: Alveol-reg_P311 
#=GF ID   Alveol-reg_P311
#=GF AC   PF11092.7
#=GF DE   Neuronal protein 3.1 (p311)
#=GF AU   Pollington J, Finn RD
#=GF SE   PRODOM
#=GF GA   25.00 25.00;
#=GF TC   42.20 40.10;
#=GF NC   24.50 18.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12417574
#=GF RT   P311 induces a TGF-beta1-independent, nonfibrogenic
#=GF RT   myofibroblast phenotype. 
#=GF RA   Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L; 
#=GF RL   J Clin Invest. 2002;110:1349-1358.
#=GF RN   [2]
#=GF RM   16484684
#=GF RT   Identification of P311 as a potential gene regulating alveolar
#=GF RT   generation. 
#=GF RA   Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH; 
#=GF RL   Am J Respir Cell Mol Biol. 2006;35:48-54.
#=GF DR   INTERPRO; IPR024417;
#=GF CC   P311 has several PEST-like motifs and is found in neuron and
#=GF CC   muscle cells. P311 could have some function in myo-fibroblast
#=GF CC   transformation and prevention of fibrosis [1]. It has also been
#=GF CC   identified as a potential regulator of alveolar generation [2].
#=GF SQ   75
#=GS M3WZB8_FELCA/2-68         AC M3WZB8.1
#=GS A0A091KGJ1_9GRUI/2-68     AC A0A091KGJ1.1
#=GS J9P5T4_CANLF/1-67         AC J9P5T4.1
#=GS D6R982_HUMAN/2-32         AC D6R982.1
#=GS L5MFN5_MYODS/10-76        AC L5MFN5.1
#=GS D6RIC9_HUMAN/2-65         AC D6RIC9.1
#=GS A0A091JH10_9AVES/2-68     AC A0A091JH10.1
#=GS A0A091EGD5_CORBR/2-67     AC A0A091EGD5.1
#=GS G5C630_HETGA/1-66         AC G5C630.1
#=GS G1P728_MYOLU/2-68         AC G1P728.1
#=GS A0A093PZI2_PHACA/2-68     AC A0A093PZI2.1
#=GS T0NM67_CAMFR/69-99        AC T0NM67.1
#=GS L5KLW8_PTEAL/1-48         AC L5KLW8.1
#=GS A0A093J6G3_PICPB/2-68     AC A0A093J6G3.1
#=GS A0A096MV06_PAPAN/2-68     AC A0A096MV06.1
#=GS D6R9Y7_HUMAN/2-33         AC D6R9Y7.1
#=GS A0A0D9RR22_CHLSB/2-68     AC A0A0D9RR22.1
#=GS H0YRW9_TAEGU/1-49         AC H0YRW9.1
#=GS NREP_RAT/2-68             AC Q80Z34.1
#=GS U3J2A7_ANAPL/1-67         AC U3J2A7.1
#=GS A0A094LHL9_9AVES/2-68     AC A0A094LHL9.1
#=GS A0A094KRS3_ANTCR/2-68     AC A0A094KRS3.1
#=GS A0A151PIK0_ALLMI/34-100   AC A0A151PIK0.1
#=GS A0A091IM00_CALAN/2-68     AC A0A091IM00.1
#=GS H2QRB3_PANTR/46-112       AC H2QRB3.1
#=GS A0A093C3U9_TAUER/2-68     AC A0A093C3U9.1
#=GS G3QMC4_GORGO/46-112       AC G3QMC4.1
#=GS A0A091TBH4_PHALP/2-68     AC A0A091TBH4.1
#=GS NREP_HUMAN/2-68           AC Q16612.1
#=GS F6QC63_MONDO/1-68         AC F6QC63.1
#=GS A0A091SS54_9AVES/2-68     AC A0A091SS54.1
#=GS A0A091KDM3_COLST/2-68     AC A0A091KDM3.1
#=GS H2PMN1_PONAB/2-68         AC H2PMN1.1
#=GS A0A093F0X8_GAVST/2-68     AC A0A093F0X8.1
#=GS A0A093LA96_EURHL/2-68     AC A0A093LA96.1
#=GS H0UZ96_CAVPO/2-68         AC H0UZ96.1
#=GS V8NDI2_OPHHA/47-108       AC V8NDI2.1
#=GS G1RL53_NOMLE/2-68         AC G1RL53.1
#=GS A0A0A0B4R5_CHAVO/2-68     AC A0A0A0B4R5.1
#=GS F1RLG1_PIG/1-69           AC F1RLG1.1
#=GS A0A091PY68_LEPDC/2-68     AC A0A091PY68.1
#=GS R4GK57_CHICK/2-68         AC R4GK57.1
#=GS A0A091L3V5_CATAU/2-68     AC A0A091L3V5.1
#=GS G3SMC9_LOXAF/1-67         AC G3SMC9.1
#=GS W5Q3T0_SHEEP/1-67         AC W5Q3T0.1
#=GS G1T1A1_RABIT/7-73         AC G1T1A1.1
#=GS A0A093PR18_9PASS/2-67     AC A0A093PR18.1
#=GS A0A091FZR2_9AVES/2-68     AC A0A091FZR2.1
#=GS NREP_PONAB/2-68           AC Q5NVD3.1
#=GS A2VDV5_BOVIN/2-68         AC A2VDV5.1
#=GS A0A091VCZ6_OPIHO/2-68     AC A0A091VCZ6.1
#=GS F6QWF7_CALJA/2-68         AC F6QWF7.1
#=GS A0A091MAB1_CARIC/2-68     AC A0A091MAB1.1
#=GS G3UR20_MELGA/1-42         AC G3UR20.1
#=GS A0A091PCD7_HALAL/2-68     AC A0A091PCD7.1
#=GS F7H2A9_MACMU/1-67         AC F7H2A9.1
#=GS S7MWP5_MYOBR/36-102       AC S7MWP5.1
#=GS A0A099YWM0_TINGU/2-68     AC A0A099YWM0.1
#=GS A0A091UP05_NIPNI/2-68     AC A0A091UP05.1
#=GS D6REJ5_HUMAN/2-32         AC D6REJ5.1
#=GS A0A093EQS9_TYTAL/2-68     AC A0A093EQS9.1
#=GS A0A0Q3MP69_AMAAE/103-169  AC A0A0Q3MP69.1
#=GS K7G4L9_PELSI/1-64         AC K7G4L9.1
#=GS A0A091PI80_APAVI/2-68     AC A0A091PI80.1
#=GS A0A091MG13_9PASS/2-68     AC A0A091MG13.1
#=GS NREP_MOUSE/2-68           AC Q07475.1
#=GS A0A093LR39_FULGA/2-68     AC A0A093LR39.1
#=GS F6VKM3_HORSE/2-68         AC F6VKM3.1
#=GS A0A091GN91_BUCRH/2-68     AC A0A091GN91.1
#=GS U3K7Y1_FICAL/2-67         AC U3K7Y1.1
#=GS A0A087RBK5_APTFO/2-68     AC A0A087RBK5.1
#=GS A0A091S4Q9_NESNO/2-68     AC A0A091S4Q9.1
#=GS A0A093I4C1_STRCA/2-68     AC A0A093I4C1.1
#=GS NREP_CHICK/2-68           AC Q90667.1
#=GS A0A091R0N5_MERNU/2-68     AC A0A091R0N5.1
M3WZB8_FELCA/2-68                    .VYYPELSVWVSQEPFPNKEMEGRLPKGSLPVPKEVNRKKDDKIEAASLT.PLGSS..ELHSPGISYLHSF.....
A0A091KGJ1_9GRUI/2-68                .VYQQRLMIWVNQKTFPTSQGDGGFPKGSLPISKEVNRKKKREGEGAYLV.PLNGY..GHHFTKINYLYSF.....
J9P5T4_CANLF/1-67                    .VCYPELSVWVSQEPFPNTEMEGRLPKGRLPIPKEVNRKKDDQMKVASLT.PPGSS..ELHAAGTSYLHSF.....
D6R982_HUMAN/2-32                    .VYYPELFVWVSQEPFPNKDMEGRLPK-----------------------.-----..-------------lrkkn
L5MFN5_MYODS/10-76                   .VYYPELAVWGSQEPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PRGSN..ELHSPSISYLHSF.....
D6RIC9_HUMAN/2-65                    .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYL---.....
A0A091JH10_9AVES/2-68                .VYQPRLMIWVSQKIFPASRGDGGFPKGSLPISKEVNRKKKSEAEGACPV.PVNGY..GHHFPKINYLYSF.....
A0A091EGD5_CORBR/2-67                .VYQPSSMIWLSQKIFPTSRGDGEFPKGNLPISKEVNRKKS-EVEGARLA.PASGY..GQHFTKINYLYAF.....
G5C630_HETGA/1-66                    .VYYPELCVWVSQEPFPDKEMEGRLPKGSLPVPKEVNRKKEE-TDAACLT.PLGSD..KLRSPSITYLHSF.....
G1P728_MYOLU/2-68                    .VYYPELAVWVSQEPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PRGSN..ELHSPSFSYLHSF.....
A0A093PZI2_PHACA/2-68                .VYQPRLTIWVSQKTFPTSQGDGGFPKGSLPISKEVNRKKKSEVEGAWLV.PVNGY..GHHFTKINYLYSF.....
T0NM67_CAMFR/69-99                   .VYYPELSVWVSQEPFPNKEMEGRLPKA----------------------.-----..-------------srgp.
L5KLW8_PTEAL/1-48                    .-------------------MEGRLPKGRLPVPKEVNRKKNDDAEAASLT.PLGSN..ELHSPRISYLYSF.....
A0A093J6G3_PICPB/2-68                .VCQPRATIWVSQKILPTSQGNGGFPKGRLPVWKEVNRKKNSEAEWACLV.PVNGY..GHHFTKINYLCSF.....
A0A096MV06_PAPAN/2-68                .VYYPELFVWVSQEPFPNKNMDGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
D6R9Y7_HUMAN/2-33                    .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVP-----------------.-----..-------------.....
A0A0D9RR22_CHLSB/2-68                .VYYPELFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
H0YRW9_TAEGU/1-49                    .VYQPGSMIWISQNIFPTSRGDGGFPKGNLPISKEVNRKKSEA-EGARL-.-----..-------------dp...
NREP_RAT/2-68                        .VYYPELLVWVSQEPFPYKEMEGGLTKGRLPVPKEVNRKKMDEPIAASLI.PPGNH..EPGSPAIGYLHPF.....
U3J2A7_ANAPL/1-67                    .VNQPRSTIWVSQKIFPTSRGDGGFPEGCLPISKEVNRKKKNEVEGACWA.PVNGY..GHHFTKINYLYSF.....
A0A094LHL9_9AVES/2-68                .VYQPRLTIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
A0A094KRS3_ANTCR/2-68                .VYQPRLTIWVSQKIFPTSHGDGGFPKGSPPVSKEVNRKKKSEVEGACLV.PVHGY..GHHFAKIDYLYSF.....
A0A151PIK0_ALLMI/34-100              .VYQPRLTIWVNQKLFPTSQGDGGFPKGYLLIPKEVNRKKNKETEALFLI.PPNDY..GHHFTKINYLYSF.....
A0A091IM00_CALAN/2-68                .VYQLRLTIWVNQKIFPTRQGDGGFPKGSLPISKEVNRKKKSEVEEAYLL.PANGY..GQHFTKINYLYSF.....
H2QRB3_PANTR/46-112                  .VYYPELFVWVSQEPFLNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
A0A093C3U9_TAUER/2-68                .VYQPRLTIWLSQKIFPTSREDGRFPKGSLPISKEVNRKKKSEEEGAGPV.PENGY..GHHFTKINYLYSF.....
G3QMC4_GORGO/46-112                  .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
A0A091TBH4_PHALP/2-68                .VYQPRLMIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGARLV.PLNGY..GHHFTKINYLYSF.....
NREP_HUMAN/2-68                      .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
F6QC63_MONDO/1-68                    .VCHPKLTVWIGQDSFPTNQEDERFLKENLPVPREVNRKKQDEIAATSLIlLSGSD..GQYSTRINYLYSF.....
A0A091SS54_9AVES/2-68                .VYQPRLTIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEVEGACPV.PVNGY..GHHFTKINYLYAF.....
A0A091KDM3_COLST/2-68                .VFQPRLTIWVSKKIFPSSRGDGGFPKGSLPISKEENRKKKSDVEGTCLV.PVNGY..GHHFNKINHLYSF.....
H2PMN1_PONAB/2-68                    .VYYPKLFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNHKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
A0A093F0X8_GAVST/2-68                .VYQPRLTIWVSQKIFPTSRGDGGFPKGSVPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
A0A093LA96_EURHL/2-68                .VYQPRLTIWVSQKTLPTSRGDGGFPKGSLPISKEINRKKRSDAEGACLV.PVNGD..GHHFTKINYLYSF.....
H0UZ96_CAVPO/2-68                    .VYYPELFVWVSQEPFPDKEMEGRLLKGSLPVPKEVNRKKNKETDAASLT.PLGSS..DLRSPSSSYLHSF.....
V8NDI2_OPHHA/47-108                  .VYHPRLT--VSQKHIPMSHGHGGFIKDNLPIPKEVNRKKNET--ALFLT.PVNGS..GHHFNKIYYL---sf...
G1RL53_NOMLE/2-68                    .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
A0A0A0B4R5_CHAVO/2-68                .VYQPRLTIWVSQKIFPTSQGDGGFPKGSLPISKEVNRKKKSEAEEACLV.PVNGY..GHHFIKINHPYSF.....
F1RLG1_PIG/1-69                      .VYYPELSVWVSQEPFPNKEMEGRLPKGRLPIPKEVNRKKDGETEAASLT.PLGSNenELHSPGISYLRSF.....
A0A091PY68_LEPDC/2-68                .VYQPRLTIWVSKKIFPTSRGDGGFPKGSLPISKEVNRKKKSEVEGACLI.PVNGY..GHHFTKINYFYSF.....
R4GK57_CHICK/2-68                    .IYQPRQTIWVSQKIFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWA.PVNGD..GHHFIKINYLYTF.....
A0A091L3V5_CATAU/2-68                .VYQPRLMIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
G3SMC9_LOXAF/1-67                    a-YYPDLFVWVSREPFPNEEMEGRLPKGRLPVPKEVNRKKGNETAAASLT.PVGGD..ELCPPRISYLFSF.....
W5Q3T0_SHEEP/1-67                    .VYYPELSVWVCQEPFPDKEMEGRLPKGRLPVPKEVNRKKDGEIGAASLT.PLGSH..ALHSPGTSYLHSF.....
G1T1A1_RABIT/7-73                    .VDCQDVSVGVSQGPSANQGLEGRLPEGGLPVPKEVNHKKMAGTSAASPT.PPGSH..GLRAPGVSYRHSF.....
A0A093PR18_9PASS/2-67                .VYQPRSMTWVSQKIFPANGGDGGFPKGNLPISKEVNRKKS-EVEGECLV.PVNGY..GRHFTKINYLYSY.....
A0A091FZR2_9AVES/2-68                .VYQPRLTIWVSQKIFPTSQGDGGFPKGSLPISKEVNRKKKNEVDGACLG.PVDGY..GHHFTKIDYLFSF.....
NREP_PONAB/2-68                      .VYYPELSVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHSF.....
A2VDV5_BOVIN/2-68                    .VYYPELSVWVCQEPFPDKEMEGRLPKGRLPVPKEVNRKKDGGIGAASLT.PLGSN..ELHSPGTSYLHSF.....
A0A091VCZ6_OPIHO/2-68                .VYQRRLRIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
F6QWF7_CALJA/2-68                    .VYYPELLVWINQEPFPNKEMEGRLPKGRLPVPKEVNRKKDDETNAASLP.PLGSN..ELRSPRISYLHFF.....
A0A091MAB1_CARIC/2-68                .VYQPRLTIWVSQKIFPTSRGDGGFPKGNLPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
G3UR20_MELGA/1-42                    s-----------------------FLQGCLPISKEVNRKKESEVEGACWA.PVNGG..GHHFTKINYL---.....
A0A091PCD7_HALAL/2-68                .VCQPRLMIWVSQKTFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGACLV.PVDGY..GHHFTQINHICSF.....
F7H2A9_MACMU/1-67                    .VYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
S7MWP5_MYOBR/36-102                  .VYYPELAVWVSREPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PRGSN..ELHSPSISYLHSF.....
A0A099YWM0_TINGU/2-68                .VYQPRLTIWVSQELFPTSRGDGGFPKGYLPISKEVNRKKKSEAEVALLT.PVNGY..GHHFTKINYLYSF.....
A0A091UP05_NIPNI/2-68                .VYQPRLTFWVSQKTFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
D6REJ5_HUMAN/2-32                    .VYYPELFVWVSQEPFPNKDMEGRLPKE----------------------.-----..-------------tsls.
A0A093EQS9_TYTAL/2-68                .VYQPMLTVWVSEKIFPISRGDGGFPKGSLPISKEVNRKKKSEMEGACLV.PVNGY..GHHFTKINYLYSF.....
A0A0Q3MP69_AMAAE/103-169             .VYQPRVMIWVSQKIFPTSRVDGGFPKGSLPISKEVNRKKKSEAEGASLI.PVNGY..GHHFTKIKYLCSF.....
K7G4L9_PELSI/1-64                    .---PRLTIWVSQELFPTSQGDGGFPKENLTIPKEVNRKKNNETEAAFLT.PANGY..GYHFTEINYLYSF.....
A0A091PI80_APAVI/2-68                .VYQPRLMILANQKMFPTSQGDGGFPKGSLPISKKVNRKKKSKAEGACLV.PVKGY..GHQFTKINYLYSF.....
A0A091MG13_9PASS/2-68                .VYQPRLMIWVNQKIFPASRGDGGFPKGSLPVSKEINCKKKSEAEETCLV.PVNGY..GHHFTKINYLYSF.....
NREP_MOUSE/2-68                      .VYYPELLVWVSQEPFAYKEMEGGLIKGRLPVPKEVNRKKMEETGAASLT.PPGSR..EFTSPATSYLHPF.....
A0A093LR39_FULGA/2-68                .VYQPKLTIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKNEVEGACLV.AVNGY..GHHFTKINYLYSF.....
F6VKM3_HORSE/2-68                    .VYYPELSVWVSQEPFPNKEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PLGSN..ELHSPRISYLHSF.....
A0A091GN91_BUCRH/2-68                .VYQPRSTIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEAEGACLV.PVNGY..GHHFTKINYLYSF.....
U3K7Y1_FICAL/2-67                    .VYQPGSMIWISQKIFPTSCGVGGFPKGNLPISKEVNRKKSEE-EGACLA.PASGY..GQHFTKINYLYSF.....
A0A087RBK5_APTFO/2-68                .VYQPRLTIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEVEGAYPV.PVNGY..GHHFTKIDYLYSF.....
A0A091S4Q9_NESNO/2-68                .VYHARLMIWVSQKIFPTSQRDGGFPKGILPISKEVNRKKKSEAKGASLV.PVNGY..GHHFARISYLYSF.....
A0A093I4C1_STRCA/2-68                .VYQPRLTVWVSQELFPTSRGDGGFPKGYLPISKEVNRKKKSEAEVAFLT.PVNGY..GHHFTKINYLYSF.....
NREP_CHICK/2-68                      .IYQPRQTIWVSQKVFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWA.PVNGD..GHHFTKINYLYTF.....
A0A091R0N5_MERNU/2-68                .VYQPRLMIWVSQKIFPTSRGDGGFPKGSLPISKEVNRKKKSEVEGSCLL.PVNGY..GHHFTKINYLYSF.....
#=GC seq_cons                        .VY.PcLhlWVSQc.FPspch-GthPKGpLPlsKEVNRKKpsEsEuAsLs.Plsu...uhH.s+IsYLaSF.....
//
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