GenomeNet

Database: Pfam
Entry: Alveol-reg_P311
LinkDB: Alveol-reg_P311
Original site: Alveol-reg_P311 
#=GF ID   Alveol-reg_P311
#=GF AC   PF11092.4
#=GF DE   Neuronal protein 3.1 (p311)
#=GF AU   Pollington J, Finn RD
#=GF SE   PRODOM
#=GF GA   25.00 25.00;
#=GF TC   42.20 40.10;
#=GF NC   24.50 18.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12417574
#=GF RT   P311 induces a TGF-beta1-independent, nonfibrogenic
#=GF RT   myofibroblast phenotype. 
#=GF RA   Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L; 
#=GF RL   J Clin Invest. 2002;110:1349-1358.
#=GF RN   [2]
#=GF RM   16484684
#=GF RT   Identification of P311 as a potential gene regulating alveolar
#=GF RT   generation. 
#=GF RA   Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH; 
#=GF RL   Am J Respir Cell Mol Biol. 2006;35:48-54.
#=GF DR   INTERPRO; IPR024417;
#=GF CC   P311 has several PEST-like motifs and is found in neuron and
#=GF CC   muscle cells. P311 could have some function in myo-fibroblast
#=GF CC   transformation and prevention of fibrosis [1]. It has also been
#=GF CC   identified as a potential regulator of alveolar generation [2].
#=GF SQ   51
#=GS M3WZB8_FELCA/2-68    AC M3WZB8.1
#=GS F1RLG1_PIG/1-69      AC F1RLG1.1
#=GS R4GK57_CHICK/2-68    AC R4GK57.1
#=GS D2HBD5_AILME/1-67    AC D2HBD5.1
#=GS G3SMC9_LOXAF/1-67    AC G3SMC9.1
#=GS J9P5T4_CANFA/1-67    AC J9P5T4.1
#=GS L5MFN5_MYODS/10-76   AC L5MFN5.1
#=GS G1T1A1_RABIT/7-73    AC G1T1A1.1
#=GS W5Q3T0_SHEEP/1-67    AC W5Q3T0.1
#=GS D6R982_HUMAN/2-32    AC D6R982.1
#=GS D6RIC9_HUMAN/2-65    AC D6RIC9.1
#=GS L8EC44_PIG/1-26      AC L8EC44.1
#=GS L8E6R1_PIG/1-43      AC L8E6R1.1
#=GS NREP_PONAB/2-68      AC Q5NVD3.1
#=GS A2VDV5_BOVIN/2-68    AC A2VDV5.1
#=GS F6QWF7_CALJA/2-68    AC F6QWF7.1
#=GS G3UR20_MELGA/1-42    AC G3UR20.1
#=GS A4D152_HUMAN/70-136  AC A4D152.1
#=GS G5C630_HETGA/1-66    AC G5C630.1
#=GS F7H2A9_MACMU/1-67    AC F7H2A9.1
#=GS T0NM67_9CETA/69-99   AC T0NM67.1
#=GS G1P728_MYOLU/2-68    AC G1P728.1
#=GS S7MWP5_MYOBR/36-102  AC S7MWP5.1
#=GS L5KLW8_PTEAL/1-48    AC L5KLW8.1
#=GS L8I5E6_9CETA/1-67    AC L8I5E6.1
#=GS D6REJ5_HUMAN/2-32    AC D6REJ5.1
#=GS D6R9Y7_HUMAN/2-33    AC D6R9Y7.1
#=GS K7G4L9_PELSI/1-64    AC K7G4L9.1
#=GS H0YRW9_TAEGU/1-49    AC H0YRW9.1
#=GS R0LFP7_ANAPL/1-42    AC R0LFP7.1
#=GS NREP_RAT/2-68        AC Q80Z34.1
#=GS H9EWE5_MACMU/2-68    AC H9EWE5.1
#=GS U3J2A7_ANAPL/1-67    AC U3J2A7.1
#=GS NREP_MOUSE/2-68      AC Q07475.1
#=GS H2QRB3_PANTR/46-112  AC H2QRB3.1
#=GS F6VKM3_HORSE/2-68    AC F6VKM3.1
#=GS G3QMC4_GORGO/46-112  AC G3QMC4.1
#=GS Q542Q5_MOUSE/2-68    AC Q542Q5.1
#=GS B5G223_TAEGU/2-50    AC B5G223.1
#=GS NREP_HUMAN/2-68      AC Q16612.1
#=GS G2HGE1_PANTR/2-68    AC G2HGE1.1
#=GS F6QC63_MONDO/1-68    AC F6QC63.1
#=GS U3K7Y1_FICAL/2-67    AC U3K7Y1.1
#=GS H2PMN1_PONAB/2-68    AC H2PMN1.1
#=GS A3RID9_PIG/2-70      AC A3RID9.1
#=GS Q2Q1N0_CEREL/1-36    AC Q2Q1N0.1
#=GS NREP_MACFA/2-68      AC Q4R541.1
#=GS H0UZ96_CAVPO/2-68    AC H0UZ96.1
#=GS V8NDI2_OPHHA/47-108  AC V8NDI2.1
#=GS G1RL53_NOMLE/2-68    AC G1RL53.1
#=GS NREP_CHICK/2-68      AC Q90667.1
M3WZB8_FELCA/2-68               .VYYPELSVWVSQEPFPNKEMEGRLPKGSLPVPKEVNRKKDDKIEAASLT.PLGSS..ELHSPGISYLHSF.....
F1RLG1_PIG/1-69                 .VYYPELSVWVSQEPFPNKEMEGRLPKGRLPIPKEVNRKKDGETEAASLT.PLGSNenELHSPGISYLRSF.....
R4GK57_CHICK/2-68               .IYQPRQTIWVSQKIFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWA.PVNGD..GHHFIKINYLYTF.....
D2HBD5_AILME/1-67               .VYYPELSVWVSQEPFPNKEMEGRLPKGRLPVPKEVNRKKDEQIEAASLT.PPGSS..ELHSPGIGYLHSF.....
G3SMC9_LOXAF/1-67               a-YYPDLFVWVSREPFPNEEMEGRLPKGRLPVPKEVNRKKGNETAAASLT.PVGGD..ELCPPRISYLFSF.....
J9P5T4_CANFA/1-67               .VCYPELSVWVSQEPFPNTEMEGRLPKGRLPIPKEVNRKKDDQMKVASLT.PPGSS..ELHAAGTSYLHSF.....
L5MFN5_MYODS/10-76              .VYYPELAVWGSQEPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PRGSN..ELHSPSISYLHSF.....
G1T1A1_RABIT/7-73               .VDCQDVSVGVSQGPSANQGLEGRLPEGGLPVPKEVNHKKMAGTSAASPT.PPGSH..GLRAPGVSYRHSF.....
W5Q3T0_SHEEP/1-67               .VYYPELSVWVCQEPFPDKEMEGRLPKGRLPVPKEVNRKKDGEIGAASLT.PLGSH..ALHSPGTSYLHSF.....
D6R982_HUMAN/2-32               .VYYPELFVWVSQEPFPNKDMEGRLPK-----------------------.-----..-------------lrkkn
D6RIC9_HUMAN/2-65               .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYL---.....
L8EC44_PIG/1-26                 .VYYPELSVWVSQEPFPNKEMEGRLPK-----------------------.-----..-------------.....
L8E6R1_PIG/1-43                 .--------------------------GRLPIPKEVNRKKDGETEAASLT.PLGSNenELHSPGISYLRSF.....
NREP_PONAB/2-68                 .VYYPELSVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHSF.....
A2VDV5_BOVIN/2-68               .VYYPELSVWVCQEPFPDKEMEGRLPKGRLPVPKEVNRKKDGGIGAASLT.PLGSN..ELHSPGTSYLHSF.....
F6QWF7_CALJA/2-68               .VYYPELLVWINQEPFPNKEMEGRLPKGRLPVPKEVNRKKDDETNAASLP.PLGSN..ELRSPRISYLHFF.....
G3UR20_MELGA/1-42               s-----------------------FLQGCLPISKEVNRKKESEVEGACWA.PVNGG..GHHFTKINYL---.....
A4D152_HUMAN/70-136             .VYYPELFLWVSQEPFPNKDMEGRLPKGRLPVPKEVNYKKNDETNAASLT.LLGSS..ELRSPRISYLHFF.....
G5C630_HETGA/1-66               .VYYPELCVWVSQEPFPDKEMEGRLPKGSLPVPKEVNRKKEE-TDAACLT.PLGSD..KLRSPSITYLHSF.....
F7H2A9_MACMU/1-67               .VYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
T0NM67_9CETA/69-99              .VYYPELSVWVSQEPFPNKEMEGRLPKA----------------------.-----..-------------srgp.
G1P728_MYOLU/2-68               .VYYPELAVWVSQEPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PRGSN..ELHSPSFSYLHSF.....
S7MWP5_MYOBR/36-102             .VYYPELAVWVSREPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PRGSN..ELHSPSISYLHSF.....
L5KLW8_PTEAL/1-48               .-------------------MEGRLPKGRLPVPKEVNRKKNDDAEAASLT.PLGSN..ELHSPRISYLYSF.....
L8I5E6_9CETA/1-67               .VYYPELSVWVCQEPFPDKEMEGRLPKGRLPVPKEVNRKKDGGIGAASLT.PLGSN..ELRSPGTSYLHSF.....
D6REJ5_HUMAN/2-32               .VYYPELFVWVSQEPFPNKDMEGRLPKE----------------------.-----..-------------tsls.
D6R9Y7_HUMAN/2-33               .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVP-----------------.-----..-------------.....
K7G4L9_PELSI/1-64               .---PRLTIWVSQELFPTSQGDGGFPKENLTIPKEVNRKKNNETEAAFLT.PANGY..GYHFTEINYLYSF.....
H0YRW9_TAEGU/1-49               .VYQPGSMIWISQNIFPTSRGDGGFPKGNLPISKEVNRKKSEA-EGARL-.-----..-------------dp...
R0LFP7_ANAPL/1-42               .-------------------------QGCLPISKEVNRKKKNEVEGACWA.PVNGY..GHHFTKINYLYSF.....
NREP_RAT/2-68                   .VYYPELLVWVSQEPFPYKEMEGGLTKGRLPVPKEVNRKKMDEPIAASLI.PPGNH..EPGSPAIGYLHPF.....
H9EWE5_MACMU/2-68               .VYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
U3J2A7_ANAPL/1-67               .VNQPRSTIWVSQKIFPTSRGDGGFPEGCLPISKEVNRKKKNEVEGACWA.PVNGY..GHHFTKINYLYSF.....
NREP_MOUSE/2-68                 .VYYPELLVWVSQEPFAYKEMEGGLIKGRLPVPKEVNRKKMEETGAASLT.PPGSR..EFTSPATSYLHPF.....
H2QRB3_PANTR/46-112             .VYYPELFVWVSQEPFLNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
F6VKM3_HORSE/2-68               .VYYPELSVWVSQEPFPNKEMEGRLPKGRLPVPKEVNRKKNDETEAASLT.PLGSN..ELHSPRISYLHSF.....
G3QMC4_GORGO/46-112             .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
Q542Q5_MOUSE/2-68               .VYYPELLVWVSQEPFAYKEMEGGLIKGRLPVPKEVNRKKMEETGAASLT.PPGSR..EFTSPATSYLHPF.....
B5G223_TAEGU/2-50               .VYQPGSMIWISQNIFPTSRGDGGFPKGNLPISKEVNRKKSEA-EGARL-.-----..-------------dp...
NREP_HUMAN/2-68                 .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
G2HGE1_PANTR/2-68               .VYYPELFVWVSQEPFLNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
F6QC63_MONDO/1-68               .VCHPKLTVWIGQDSFPTNQEDERFLKENLPVPREVNRKKQDEIAATSLIlLSGSD..GQYSTRINYLYSF.....
U3K7Y1_FICAL/2-67               .VYQPGSMIWISQKIFPTSCGVGGFPKGNLPISKEVNRKKSEE-EGACLA.PASGY..GQHFTKINYLYSF.....
H2PMN1_PONAB/2-68               .VYYPKLFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNHKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
A3RID9_PIG/2-70                 .VYYPELSVWVSQEPFPNKEMEGRLPKGRLPIPKEVNRKKDGETEAASLT.PLGSNenELHSPGISYLRSF.....
Q2Q1N0_CEREL/1-36               .-------------------------------PKEVNRKKDGEMGAASLT.PLGGN..ELHSPGTSYLHSF.....
NREP_MACFA/2-68                 .VYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
H0UZ96_CAVPO/2-68               .VYYPELFVWVSQEPFPDKEMEGRLLKGSLPVPKEVNRKKNKETDAASLT.PLGSS..DLRSPSSSYLHSF.....
V8NDI2_OPHHA/47-108             .VYHPRLT--VSQKHIPMSHGHGGFIKDNLPIPKEVNRKKNET--ALFLT.PVNGS..GHHFNKIYYL---sf...
G1RL53_NOMLE/2-68               .VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLT.PLGSS..ELRSPRISYLHFF.....
NREP_CHICK/2-68                 .IYQPRQTIWVSQKVFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWA.PVNGD..GHHFTKINYLYTF.....
#=GC seq_cons                   .VYYPELhVWVSQEPFPsK-MEGRLPKGRLPVPKEVNRKKscEspAASLT.PlGSs..EL+SPtISYL+.F.....
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