GenomeNet

Database: Pfam
Entry: Alveol-reg_P311
LinkDB: Alveol-reg_P311
Original site: Alveol-reg_P311 
#=GF ID   Alveol-reg_P311
#=GF AC   PF11092.3
#=GF DE   Neuronal protein 3.1 (p311)
#=GF AU   Pollington J, Finn RD
#=GF SE   PRODOM
#=GF GA   25.00 25.00;
#=GF TC   56.20 56.10;
#=GF NC   20.10 16.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12417574
#=GF RT   P311 induces a TGF-beta1-independent, nonfibrogenic
#=GF RT   myofibroblast phenotype. 
#=GF RA   Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L; 
#=GF RL   J Clin Invest. 2002;110:1349-1358.
#=GF RN   [2]
#=GF RM   16484684
#=GF RT   Identification of P311 as a potential gene regulating alveolar
#=GF RT   generation. 
#=GF RA   Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH; 
#=GF RL   Am J Respir Cell Mol Biol. 2006;35:48-54.
#=GF DR   INTERPRO; IPR024417;
#=GF CC   P311 has several PEST-like motifs and is found in neuron and
#=GF CC   muscle cells. P311 could have some function in myo-fibroblast
#=GF CC   transformation and prevention of fibrosis [1]. It has also been
#=GF CC   identified as a potential regulator of alveolar generation [2].
#=GF SQ   38
#=GS F1RLG1_PIG/1-69      AC F1RLG1.1
#=GS D2HBD5_AILME/1-67    AC D2HBD5.1
#=GS G3SMC9_LOXAF/1-67    AC G3SMC9.1
#=GS G3QMC4_GORGO/45-112  AC G3QMC4.1
#=GS D6REJ5_HUMAN/1-33    AC D6REJ5.1
#=GS Q542Q5_MOUSE/1-68    AC Q542Q5.1
#=GS NREP_MACFA/1-68      AC Q4R541.1
#=GS H9EWE5_MACMU/1-68    AC H9EWE5.1
#=GS G3UR20_MELGA/1-42    AC G3UR20.1
#=GS NREP_RAT/1-68        AC Q80Z34.1
#=GS H0UZ96_CAVPO/1-68    AC H0UZ96.1
#=GS G5C630_HETGA/1-66    AC G5C630.1
#=GS F7H2A9_MACMU/1-67    AC F7H2A9.1
#=GS A4D152_HUMAN/69-136  AC A4D152.1
#=GS H2PMN1_PONAB/1-68    AC H2PMN1.1
#=GS F6QWF7_CALJA/1-68    AC F6QWF7.1
#=GS H0YRW9_TAEGU/1-49    AC H0YRW9.1
#=GS D6RIC9_HUMAN/1-65    AC D6RIC9.1
#=GS A3RID9_PIG/1-70      AC A3RID9.1
#=GS G1T1A1_RABIT/6-73    AC G1T1A1.1
#=GS F6VKM3_HORSE/1-68    AC F6VKM3.1
#=GS NREP_MOUSE/1-68      AC Q07475.1
#=GS G1P728_MYOLU/1-68    AC G1P728.1
#=GS H2QRB3_PANTR/45-112  AC H2QRB3.1
#=GS F1NE26_CHICK/1-68    AC F1NE26.1
#=GS G1RL53_NOMLE/1-68    AC G1RL53.1
#=GS G2HGE1_PANTR/1-68    AC G2HGE1.1
#=GS D6R982_HUMAN/1-32    AC D6R982.1
#=GS H2PG93_PONAB/1-68    AC H2PG93.1
#=GS A2VDV5_BOVIN/1-68    AC A2VDV5.1
#=GS B5G223_TAEGU/1-50    AC B5G223.1
#=GS F6QC63_MONDO/1-68    AC F6QC63.1
#=GS NREP_HUMAN/1-68      AC Q16612.1
#=GS D6R9Y7_HUMAN/1-33    AC D6R9Y7.1
#=GS NREP_CHICK/1-68      AC Q90667.1
#=GS Q2Q1N0_CEREL/1-36    AC Q2Q1N0.1
#=GS NREP_PONAB/1-68      AC Q5NVD3.1
#=GS F1NKR9_CHICK/1-67    AC F1NKR9.1
F1RLG1_PIG/1-69                 .-VYYPELSVWVSQEPFPNKEMEGRLPKGRLPIPKEVNRKKDGETEAASLTPL.GSNenELHSPGISYLRSF......
D2HBD5_AILME/1-67               .-VYYPELSVWVSQEPFPNKEMEGRLPKGRLPVPKEVNRKKDEQIEAASLTPP.GSS..ELHSPGIGYLHSF......
G3SMC9_LOXAF/1-67               a--YYPDLFVWVSREPFPNEEMEGRLPKGRLPVPKEVNRKKGNETAAASLTPV.GGD..ELCPPRISYLFSF......
G3QMC4_GORGO/45-112             c-VYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
D6REJ5_HUMAN/1-33               .MVYYPELFVWVSQEPFPNKDMEGRLPK-------------------------.---..-------------etslsp
Q542Q5_MOUSE/1-68               .MVYYPELLVWVSQEPFAYKEMEGGLIKGRLPVPKEVNRKKMEETGAASLTPP.GSR..EFTSPATSYLHPF......
NREP_MACFA/1-68                 .MVYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
H9EWE5_MACMU/1-68               .MVYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
G3UR20_MELGA/1-42               s------------------------FLQGCLPISKEVNRKKESEVEGACWAPV.NGG..GHHFTKINYL---......
NREP_RAT/1-68                   .MVYYPELLVWVSQEPFPYKEMEGGLTKGRLPVPKEVNRKKMDEPIAASLIPP.GNH..EPGSPAIGYLHPF......
H0UZ96_CAVPO/1-68               q-VYYPELFVWVSQEPFPDKEMEGRLLKGSLPVPKEVNRKKNKETDAASLTPL.GSS..DLRSPSSSYLHSF......
G5C630_HETGA/1-66               .-VYYPELCVWVSQEPFPDKEMEGRLPKGSLPVPKEVNRKKE-ETDAACLTPL.GSD..KLRSPSITYLHSF......
F7H2A9_MACMU/1-67               .-VYYPERFVWVSQEPFPNKNMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
A4D152_HUMAN/69-136             .MVYYPELFLWVSQEPFPNKDMEGRLPKGRLPVPKEVNYKKNDETNAASLTLL.GSS..ELRSPRISYLHFF......
H2PMN1_PONAB/1-68               .MVYYPKLFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNHKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
F6QWF7_CALJA/1-68               .MVYYPELLVWINQEPFPNKEMEGRLPKGRLPVPKEVNRKKDDETNAASLPPL.GSN..ELRSPRISYLHFF......
H0YRW9_TAEGU/1-49               .-VYQPGSMIWISQNIFPTSRGDGGFPKGNLPISKEVNRKK-SEAEGARLDP-.---..-------------......
D6RIC9_HUMAN/1-65               .MVYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYL---......
A3RID9_PIG/1-70                 .MVYYPELSVWVSQEPFPNKEMEGRLPKGRLPIPKEVNRKKDGETEAASLTPL.GSNenELHSPGISYLRSF......
G1T1A1_RABIT/6-73               m-VDCQDVSVGVSQGPSANQGLEGRLPEGGLPVPKEVNHKKMAGTSAASPTPP.GSH..GLRAPGVSYRHSF......
F6VKM3_HORSE/1-68               .MVYYPELSVWVSQEPFPNKEMEGRLPKGRLPVPKEVNRKKNDETEAASLTPL.GSN..ELHSPRISYLHSF......
NREP_MOUSE/1-68                 .MVYYPELLVWVSQEPFAYKEMEGGLIKGRLPVPKEVNRKKMEETGAASLTPP.GSR..EFTSPATSYLHPF......
G1P728_MYOLU/1-68               q-VYYPELAVWVSQEPFPNEEMEGRLPKGRLPVPKEVNRKKNDETEAASLTPR.GSN..ELHSPSFSYLHSF......
H2QRB3_PANTR/45-112             c-VYYPELFVWVSQEPFLNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
F1NE26_CHICK/1-68               .MIYQPRQTIWVSQKIFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWAPV.NGD..GHHFIKINYLYTF......
G1RL53_NOMLE/1-68               .MVYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
G2HGE1_PANTR/1-68               .MVYYPELFVWVSQEPFLNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
D6R982_HUMAN/1-32               .MVYYPELFVWVSQEPFPNKDMEGRLPKL------------------------.---..-------------rkkn..
H2PG93_PONAB/1-68               .MVYYPELSVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
A2VDV5_BOVIN/1-68               .MVYYPELSVWVCQEPFPDKEMEGRLPKGRLPVPKEVNRKKDGGIGAASLTPL.GSN..ELHSPGTSYLHSF......
B5G223_TAEGU/1-50               .MVYQPGSMIWISQNIFPTSRGDGGFPKGNLPISKEVNRKK-SEAEGARLDP-.---..-------------......
F6QC63_MONDO/1-68               v--CHPKLTVWIGQDSFPTNQEDERFLKENLPVPREVNRKKQDEIAATSLILLsGSD..GQYSTRINYLYSF......
NREP_HUMAN/1-68                 .MVYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHFF......
D6R9Y7_HUMAN/1-33               .MVYYPELFVWVSQEPFPNKDMEGRLPKGRLPVP-------------------.---..-------------......
NREP_CHICK/1-68                 .MIYQPRQTIWVSQKVFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWAPV.NGD..GHHFTKINYLYTF......
Q2Q1N0_CEREL/1-36               .--------------------------------PKEVNRKKDGEMGAASLTPL.GGN..ELHSPGTSYLHSF......
NREP_PONAB/1-68                 .MVYYPELSVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPL.GSS..ELRSPRISYLHSF......
F1NKR9_CHICK/1-67               .-IYQPRQTIWVSQKIFPTSQGDGGFLKGCLPISKEVNRKKESEVEGACWAPV.NGD..GHHFIKINYLYTF......
#=GC seq_cons                   .MVYYPELhVWVSQEPFPNK-MEGRLPKGRLPVPKEVNRKKssETsAASLTPl.GSs..EL+SPpISYLH.F......
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