GenomeNet

Database: Pfam
Entry: Asp_protease
LinkDB: Asp_protease
Original site: Asp_protease 
#=GF ID   Asp_protease
#=GF AC   PF09668.8
#=GF DE   Aspartyl protease
#=GF AU   Mistry J, Wood V
#=GF SE   Pfam-B_9589 (release 20.0)
#=GF GA   20.60 20.60;
#=GF TC   20.60 20.60;
#=GF NC   20.50 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Aspartate_protease
#=GF RN   [1]
#=GF RM   17010377
#=GF RT   Ddi1, a eukaryotic protein with the retroviral protease fold. 
#=GF RA   Sirkis R, Gerst JE, Fass D; 
#=GF RL   J Mol Biol. 2006;364:376-387.
#=GF DR   INTERPRO; IPR019103;
#=GF CC   This family of eukaryotic aspartyl proteases have a fold similar
#=GF CC   to retroviral proteases which implies they function
#=GF CC   proteolytically during regulated protein turnover [1].
#=GF SQ   685
#=GS K7LIR6_SOYBN/27-79         AC K7LIR6.1
#=GS G3RAE7_GORGO/220-343       AC G3RAE7.1
#=GS A0A067G624_CITSI/173-230   AC A0A067G624.1
#=GS I3MQW6_ICTTR/118-226       AC I3MQW6.1
#=GS S9WV36_9CETA/72-195        AC S9WV36.1
#=GS A0A0F8UZN5_9EURO/191-314   AC A0A0F8UZN5.1
#=GS NRIP3_PONAB/86-208         AC Q5R7G1.1
#=GS G4VA18_SCHMA/1-18          AC G4VA18.1
#=GS Q4Z4J8_PLABA/228-351       AC Q4Z4J8.1
#=GS G5BRT1_HETGA/212-335       AC G5BRT1.1
#=GS J9I4F6_9SPIT/247-370       AC J9I4F6.1
#=GS G8Y404_PICSO/187-311       AC G8Y404.1
#=GS C1GYT2_PARBA/180-303       AC C1GYT2.1
#=GS W9WVQ0_9EURO/159-282       AC W9WVQ0.1
#=GS D6WK92_TRICA/194-317       AC D6WK92.1
#=GS Q8LMX1_ORYSJ/93-220        AC Q8LMX1.1
#=GS F6PQL0_MONDO/149-254       AC F6PQL0.2
#=GS A0A0N5BE22_STREA/276-384   AC A0A0N5BE22.1
#=GS G8Y120_PICSO/187-311       AC G8Y120.1
#=GS G3TM23_LOXAF/212-335       AC G3TM23.1
#=GS G1QDW9_MYOLU/165-288       AC G1QDW9.1
#=GS A0A0F4ZAM6_9PEZI/177-300   AC A0A0F4ZAM6.1
#=GS F2TU83_AJEDA/404-527       AC F2TU83.1
#=GS A0A068Y9Y4_ECHMU/178-301   AC A0A068Y9Y4.1
#=GS A0A0C2NBS9_THEKT/274-387   AC A0A0C2NBS9.1
#=GS X6M8A7_RETFI/86-125        AC X6M8A7.1
#=GS A4RTH7_OSTLU/182-306       AC A4RTH7.1
#=GS A0A067BXU4_SAPPC/189-312   AC A0A067BXU4.1
#=GS A0A0N5BTY1_STREA/53-176    AC A0A0N5BTY1.1
#=GS M4AS13_XIPMA/74-195        AC M4AS13.1
#=GS U4LJA0_PYROM/226-349       AC U4LJA0.1
#=GS L9L0N8_TUPCH/212-335       AC L9L0N8.1
#=GS A0A0N4UIP0_DRAME/19-143    AC A0A0N4UIP0.1
#=GS A0A096MZA8_PAPAN/221-344   AC A0A096MZA8.1
#=GS F7E081_HORSE/166-289       AC F7E081.1
#=GS K0RT83_THAOC/165-287       AC K0RT83.1
#=GS H0ZDA5_TAEGU/97-214        AC H0ZDA5.1
#=GS A0A066WU84_COLSU/157-280   AC A0A066WU84.1
#=GS T1KQZ0_TETUR/210-333       AC T1KQZ0.1
#=GS M7WZT2_RHOT1/174-297       AC M7WZT2.1
#=GS A7TLS8_VANPO/180-302       AC A7TLS8.1
#=GS A0A0N5B8W0_STREA/373-501   AC A0A0N5B8W0.1
#=GS A0A0J7KIJ7_LASNI/64-191    AC A0A0J7KIJ7.1
#=GS F7FRY1_CALJA/213-255       AC F7FRY1.1
#=GS W5GQJ1_WHEAT/169-292       AC W5GQJ1.1
#=GS F1NA88_CHICK/93-214        AC F1NA88.2
#=GS U9UP80_RHIID/161-214       AC U9UP80.1
#=GS Q7RA33_PLAYO/228-351       AC Q7RA33.1
#=GS K7LIS0_SOYBN/29-81         AC K7LIS0.1
#=GS A0A0N4ZA87_PARTI/42-167    AC A0A0N4ZA87.1
#=GS I3KMX1_ORENI/133-253       AC I3KMX1.1
#=GS DDI2_DANRE/222-345         AC Q6TH22.1
#=GS M0U2J7_MUSAM/172-295       AC M0U2J7.1
#=GS F1RNK2_PIG/102-218         AC F1RNK2.2
#=GS X6M8A7_RETFI/23-91         AC X6M8A7.1
#=GS H2TXE6_TAKRU/213-336       AC H2TXE6.1
#=GS S9X6P0_9CETA/18-140        AC S9X6P0.1
#=GS M7UMC5_BOTF1/196-319       AC M7UMC5.1
#=GS A0A0N4VX58_HAEPC/1-77      AC A0A0N4VX58.1
#=GS H0ZSE9_TAEGU/70-187        AC H0ZSE9.1
#=GS M3YDE5_MUSPF/115-231       AC M3YDE5.1
#=GS T1I4S9_RHOPR/138-261       AC T1I4S9.1
#=GS A0A059BWV6_EUCGR/174-297   AC A0A059BWV6.1
#=GS M2W1W3_GALSU/133-256       AC M2W1W3.1
#=GS N4UGM0_FUSC1/185-308       AC N4UGM0.1
#=GS S8E555_9LAMI/139-262       AC S8E555.1
#=GS T0R2T8_9STRA/189-312       AC T0R2T8.1
#=GS T0L7D0_COLGC/160-283       AC T0L7D0.1
#=GS A0A0A1PE58_9FUNG/76-200    AC A0A0A1PE58.1
#=GS A0A0N1HCM8_9EURO/371-494   AC A0A0N1HCM8.1
#=GS A0C6T9_PARTE/167-290       AC A0C6T9.1
#=GS W9WHC0_9EURO/159-282       AC W9WHC0.1
#=GS W5K3T1_ASTMX/212-335       AC W5K3T1.1
#=GS F7GE01_MACMU/220-343       AC F7GE01.1
#=GS W2QLU2_PHYPN/188-311       AC W2QLU2.1
#=GS F7G094_MONDO/115-235       AC F7G094.2
#=GS A0A0N5E5T6_TRIMR/168-264   AC A0A0N5E5T6.1
#=GS A0A0N5C8T1_STREA/198-323   AC A0A0N5C8T1.1
#=GS Q38FA2_TRYB2/142-265       AC Q38FA2.1
#=GS I0Z925_9CHLO/328-360       AC I0Z925.1
#=GS K7UR93_MAIZE/172-295       AC K7UR93.1
#=GS W2QL00_PHYPN/43-166        AC W2QL00.1
#=GS J9HY95_AEDAE/212-335       AC J9HY95.1
#=GS A0A0L7LE42_9NEOP/194-242   AC A0A0L7LE42.1
#=GS K7UEU8_MAIZE/172-295       AC K7UEU8.1
#=GS A6QLV8_BOVIN/87-208        AC A6QLV8.1
#=GS W6PW70_PENRO/187-310       AC W6PW70.1
#=GS NRIP2_HUMAN/140-255        AC Q9BQI9.3
#=GS A0A094DU31_9PEZI/186-309   AC A0A094DU31.1
#=GS G5BUX0_HETGA/267-389       AC G5BUX0.1
#=GS X0JFL2_FUSOX/184-307       AC X0JFL2.1
#=GS DDI1_EMENI/172-295         AC Q5AY89.2
#=GS A0A0N5AMU8_9BILA/215-339   AC A0A0N5AMU8.1
#=GS A0A063C6J3_9HYPO/169-292   AC A0A063C6J3.1
#=GS M7CBK1_CHEMY/219-342       AC M7CBK1.1
#=GS W9YSF8_9EURO/158-281       AC W9YSF8.1
#=GS A0A094IJS7_9PEZI/186-309   AC A0A094IJS7.1
#=GS Q17569_CAEEL/221-345       AC Q17569.2
#=GS I1G886_AMPQE/229-353       AC I1G886.1
#=GS A0A059BXT2_EUCGR/174-297   AC A0A059BXT2.1
#=GS NRIP3_HUMAN/87-209         AC Q9NQ35.1
#=GS G1SC27_NOMLE/220-343       AC G1SC27.1
#=GS J9K8I8_ACYPI/199-322       AC J9K8I8.2
#=GS F6SX65_MACMU/139-254       AC F6SX65.1
#=GS A0A0D9YNT5_9ORYZ/174-297   AC A0A0D9YNT5.1
#=GS A0A0D9MVP4_ASPFL/196-319   AC A0A0D9MVP4.1
#=GS U6L9I2_EIMTE/291-414       AC U6L9I2.1
#=GS A0A077YX09_TRITR/313-436   AC A0A077YX09.1
#=GS W5H4P2_WHEAT/172-295       AC W5H4P2.1
#=GS H0ZZU0_TAEGU/1-82          AC H0ZZU0.1
#=GS A0A087YEF2_POEFO/232-355   AC A0A087YEF2.2
#=GS A0A0M3K8G3_ANISI/71-118    AC A0A0M3K8G3.1
#=GS A0A0K0F4E5_9BILA/87-192    AC A0A0K0F4E5.1
#=GS C1G7M5_PARBD/171-294       AC C1G7M5.1
#=GS V9FR99_PHYPR/188-311       AC V9FR99.1
#=GS A5K1D6_PLAVS/232-355       AC A5K1D6.1
#=GS A0A0D2V2I0_GOSRA/173-296   AC A0A0D2V2I0.1
#=GS A0A0M8P7A3_9EURO/188-311   AC A0A0M8P7A3.1
#=GS Q4E0H2_TRYCC/208-331       AC Q4E0H2.1
#=GS V4WGZ5_9ROSI/173-296       AC V4WGZ5.1
#=GS A0A0G2FJA3_9PEZI/202-325   AC A0A0G2FJA3.1
#=GS H3B5T7_LATCH/1-96          AC H3B5T7.1
#=GS U6GFE4_EIMAC/290-413       AC U6GFE4.1
#=GS H0VVH1_CAVPO/179-304       AC H0VVH1.1
#=GS G3I958_CRIGR/200-322       AC G3I958.1
#=GS A0A0G4MGJ2_9PEZI/4-127     AC A0A0G4MGJ2.1
#=GS K4E4N7_TRYCR/208-331       AC K4E4N7.1
#=GS H2UKX9_TAKRU/111-212       AC H2UKX9.1
#=GS A0A094B576_9PEZI/1-101     AC A0A094B576.1
#=GS A0A074S1C6_9HOMO/159-282   AC A0A074S1C6.1
#=GS A0A0F8B749_CERFI/219-342   AC A0A0F8B749.1
#=GS W1NTM4_AMBTC/151-274       AC W1NTM4.1
#=GS T5AB64_OPHSC/164-287       AC T5AB64.1
#=GS S8AMY1_PENO1/178-301       AC S8AMY1.1
#=GS NRIP3_MOUSE/86-208         AC Q9JJR9.1
#=GS A0A061FBN2_THECC/173-296   AC A0A061FBN2.1
#=GS C5XXJ0_SORBI/173-296       AC C5XXJ0.1
#=GS L9KR66_TUPCH/174-297       AC L9KR66.1
#=GS G0P8V6_CAEBE/226-350       AC G0P8V6.1
#=GS A0A0K9PYF7_ZOSMR/173-296   AC A0A0K9PYF7.1
#=GS A0A024VKJ8_PLAFA/222-345   AC A0A024VKJ8.1
#=GS U6JUQ2_9EIME/273-396       AC U6JUQ2.1
#=GS V9FPF7_PHYPR/43-166        AC V9FPF7.1
#=GS S9UNU9_9TRYP/72-195        AC S9UNU9.1
#=GS A0A0M0U9D1_9PEZI/165-288   AC A0A0M0U9D1.1
#=GS A0A0B4HA31_9HYPO/163-286   AC A0A0B4HA31.1
#=GS A0A0D9MH09_9EURO/188-311   AC A0A0D9MH09.1
#=GS S3CB29_OPHP1/215-338       AC S3CB29.1
#=GS DDI1_DICDI/180-303         AC Q54JB0.1
#=GS A0A0N4ZVY8_PARTI/209-333   AC A0A0N4ZVY8.1
#=GS A0A0Q9WRN7_DROWI/236-359   AC A0A0Q9WRN7.1
#=GS F1P9B7_CANLF/120-226       AC F1P9B7.2
#=GS A0A0N0VCU8_9TRYP/212-335   AC A0A0N0VCU8.1
#=GS A0A0N4TWV6_BRUPA/199-323   AC A0A0N4TWV6.1
#=GS G1PQN1_MYOLU/27-150        AC G1PQN1.1
#=GS J0DZU4_LOALO/200-324       AC J0DZU4.1
#=GS DDI1_ASPOR/164-287         AC Q2USD7.2
#=GS Q59ZT3_CANAL/163-287       AC Q59ZT3.1
#=GS A0A0A1UCM7_ENTIV/1-88      AC A0A0A1UCM7.1
#=GS A0A0L6DH27_CRYGA/470-579   AC A0A0L6DH27.1
#=GS B2WMP3_PYRTR/155-278       AC B2WMP3.1
#=GS A4H334_LEIBR/166-289       AC A4H334.1
#=GS G1LBR2_AILME/29-152        AC G1LBR2.1
#=GS H3FYQ3_PRIPA/320-368       AC H3FYQ3.1
#=GS DDI1_DEBHA/185-309         AC Q6BK42.2
#=GS F6YU38_HORSE/81-202        AC F6YU38.1
#=GS Q6GQT2_MOUSE/97-219        AC Q6GQT2.1
#=GS A7APU1_BABBO/301-424       AC A7APU1.1
#=GS DDI1_RAT/226-349           AC A0JPP7.1
#=GS H2TXE8_TAKRU/227-350       AC H2TXE8.1
#=GS A0A0N4W664_HAEPC/1-77      AC A0A0N4W664.1
#=GS V7BL48_PHAVU/178-301       AC V7BL48.1
#=GS A0A0F2MIJ5_SPOSC/197-320   AC A0A0F2MIJ5.1
#=GS W7A9H7_9APIC/229-352       AC W7A9H7.1
#=GS K1VJ91_TRIAC/158-272       AC K1VJ91.1
#=GS D5G787_TUBMM/163-286       AC D5G787.1
#=GS F7C7X8_MONDO/211-334       AC F7C7X8.1
#=GS U1NZ75_ASCSU/289-413       AC U1NZ75.1
#=GS A0A059BWH1_EUCGR/174-297   AC A0A059BWH1.1
#=GS I3M0J8_ICTTR/98-219        AC I3M0J8.1
#=GS F4JC86_ARATH/177-300       AC F4JC86.1
#=GS V4NQ47_EUTSA/174-297       AC V4NQ47.1
#=GS X0CNF2_FUSOX/184-307       AC X0CNF2.1
#=GS W4W658_ATTCE/203-326       AC W4W658.1
#=GS W9CVS5_9HELO/233-356       AC W9CVS5.1
#=GS A7S5W6_NEMVE/202-246       AC A7S5W6.1
#=GS A0A067GF09_CITSI/1-66      AC A0A067GF09.1
#=GS G8BL27_CANPC/180-304       AC G8BL27.1
#=GS G1S712_NOMLE/86-208        AC G1S712.1
#=GS DDI1_CHAGB/190-313         AC Q2H085.2
#=GS A0A084QUR0_9HYPO/239-362   AC A0A084QUR0.1
#=GS H2W2Y6_CAEJA/1-105         AC H2W2Y6.2
#=GS H2PY38_PANTR/212-335       AC H2PY38.1
#=GS E9DEW5_COCPS/191-314       AC E9DEW5.1
#=GS G1U603_RABIT/165-288       AC G1U603.1
#=GS K3W291_FUSPC/158-281       AC K3W291.1
#=GS G3HYK7_CRIGR/148-271       AC G3HYK7.1
#=GS S9VYF2_SCHCR/229-352       AC S9VYF2.1
#=GS A0A0K0FHG8_9BILA/208-336   AC A0A0K0FHG8.1
#=GS K1PB10_CRAGI/205-328       AC K1PB10.1
#=GS G4TV87_PIRID/156-279       AC G4TV87.1
#=GS H0UUW6_CAVPO/231-354       AC H0UUW6.1
#=GS E6ZU46_SPORE/165-289       AC E6ZU46.1
#=GS F0VB08_NEOCL/282-405       AC F0VB08.1
#=GS A0A0L0NRT2_9ASCO/175-299   AC A0A0L0NRT2.1
#=GS H2NE50_PONAB/86-208        AC H2NE50.1
#=GS K7LAF0_SOYBN/178-301       AC K7LAF0.1
#=GS H2N8Z2_PONAB/212-335       AC H2N8Z2.1
#=GS G3PF41_GASAC/222-345       AC G3PF41.1
#=GS G1KJE2_ANOCA/90-214        AC G1KJE2.2
#=GS M3X3Y0_FELCA/86-208        AC M3X3Y0.1
#=GS K3YSW9_SETIT/172-295       AC K3YSW9.1
#=GS S8A736_DACHA/214-337       AC S8A736.1
#=GS E7QE30_YEASZ/180-302       AC E7QE30.1
#=GS D4A2K5_RAT/89-208          AC D4A2K5.1
#=GS J3LAL4_ORYBR/174-297       AC J3LAL4.1
#=GS E1ZZT6_CAMFO/203-326       AC E1ZZT6.1
#=GS L8WJM3_THACA/188-293       AC L8WJM3.1
#=GS B7P906_IXOSC/180-303       AC B7P906.1
#=GS M7TI77_EUTLA/210-333       AC M7TI77.1
#=GS A0A093Y0P1_9PEZI/203-326   AC A0A093Y0P1.1
#=GS H3ED35_PRIPA/101-164       AC H3ED35.1
#=GS A0BJQ8_PARTE/175-298       AC A0BJQ8.1
#=GS W7T228_9STRA/208-331       AC W7T228.1
#=GS F7DR87_HORSE/166-289       AC F7DR87.1
#=GS H3DV99_PRIPA/8-114         AC H3DV99.1
#=GS A0A0D3BB32_BRAOL/176-299   AC A0A0D3BB32.1
#=GS G1QGG0_MYOLU/216-339       AC G1QGG0.1
#=GS A0A098VT72_9MICR/81-215    AC A0A098VT72.1
#=GS A0A0A1SYP8_9HYPO/235-358   AC A0A0A1SYP8.1
#=GS F6XNN8_MONDO/204-327       AC F6XNN8.1
#=GS DDI1_BOVIN/214-337         AC Q2T9Z1.1
#=GS G4VA17_SCHMA/186-315       AC G4VA17.1
#=GS E3L4Z5_PUCGT/114-162       AC E3L4Z5.2
#=GS A8HZC5_CHLRE/196-320       AC A8HZC5.1
#=GS H2NF42_PONAB/220-343       AC H2NF42.1
#=GS W5NIJ1_LEPOC/130-257       AC W5NIJ1.1
#=GS V5BLJ9_TRYCR/208-331       AC V5BLJ9.1
#=GS L5LNF1_MYODS/207-330       AC L5LNF1.1
#=GS A0A0K0FAC0_9BILA/199-324   AC A0A0K0FAC0.1
#=GS G3T625_LOXAF/96-219        AC G3T625.1
#=GS Q6H734_ORYSJ/174-297       AC Q6H734.1
#=GS A0A0K0DZB9_STRER/206-331   AC A0A0K0DZB9.1
#=GS F7EEI9_XENTR/31-156        AC F7EEI9.1
#=GS W5J3X2_ANODA/223-346       AC W5J3X2.1
#=GS G3W3R3_SARHA/167-290       AC G3W3R3.1
#=GS K7JC98_NASVI/130-188       AC K7JC98.1
#=GS A0A0K0D0R0_ANGCA/71-160    AC A0A0K0D0R0.1
#=GS F6SLF4_HORSE/218-341       AC F6SLF4.1
#=GS M4FE62_BRARP/262-385       AC M4FE62.1
#=GS E9QAD1_MOUSE/105-218       AC E9QAD1.1
#=GS G1MLG4_AILME/217-340       AC G1MLG4.1
#=GS E4UPU9_ARTGP/182-305       AC E4UPU9.1
#=GS K1X400_MARBU/217-340       AC K1X400.1
#=GS A6RBV6_AJECN/405-528       AC A6RBV6.1
#=GS C4M3E1_ENTHI/16-141        AC C4M3E1.1
#=GS W7U1J9_9STRA/300-383       AC W7U1J9.1
#=GS A0A0N4V871_ENTVE/77-201    AC A0A0N4V871.1
#=GS A0A0P9C1E1_DROAN/226-349   AC A0A0P9C1E1.1
#=GS A0A075ATT9_9FUNG/136-259   AC A0A075ATT9.1
#=GS A0A0Q9WBU2_DROVI/234-357   AC A0A0Q9WBU2.1
#=GS A0A087SHW2_AUXPR/178-300   AC A0A087SHW2.1
#=GS G1SAA9_NOMLE/212-335       AC G1SAA9.2
#=GS Q9VXF9_DROME/217-340       AC Q9VXF9.1
#=GS A0A087GH71_ARAAL/84-201    AC A0A087GH71.1
#=GS H2N1T7_ORYLA/223-265       AC H2N1T7.1
#=GS W4KDY3_9HOMO/211-248       AC W4KDY3.1
#=GS A8WMU3_CAEBR/151-277       AC A8WMU3.2
#=GS C0NNF5_AJECG/171-294       AC C0NNF5.1
#=GS J3NNG2_GAGT3/200-323       AC J3NNG2.1
#=GS S0DMK8_GIBF5/158-277       AC S0DMK8.1
#=GS G8Z278_SOLLC/175-298       AC G8Z278.1
#=GS G7XGH9_ASPKW/232-355       AC G7XGH9.1
#=GS A0A0D3F224_9ORYZ/174-297   AC A0A0D3F224.1
#=GS B6QRU4_TALMQ/196-319       AC B6QRU4.1
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