GenomeNet

Database: Pfam
Entry: Asp_protease_2
LinkDB: Asp_protease_2
Original site: Asp_protease_2 
#=GF ID   Asp_protease_2
#=GF AC   PF13650.2
#=GF DE   Aspartyl protease
#=GF AU   Coggill P
#=GF SE   Jackhmmer:C6QGC6
#=GF GA   24.00 24.00;
#=GF TC   24.00 24.00;
#=GF NC   23.90 23.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Aspartate_protease
#=GF DR   MEROPS; A28;
#=GF DR   MEROPS; A32;
#=GF CC   This family consists of predicted aspartic proteases, typically
#=GF CC   from 180 to 230 amino acids in length, in MEROPS clan AA. This
#=GF CC   model describes the well-conserved 121-residue C-terminal
#=GF CC   region. The poorly conserved, variable length N-terminal region
#=GF CC   usually contains a predicted transmembrane helix.
#=GF SQ   5898
#=GS W0INS6_RHILT/70-159         AC W0INS6.1
#=GS W6SE82_9CYAN/72-158         AC W6SE82.1
#=GS K5YG10_FRATL/191-289        AC K5YG10.1
#=GS B2S598_BRUA1/127-216        AC B2S598.1
#=GS A0A017N2V0_BACFG/160-252    AC A0A017N2V0.1
#=GS W4MAZ0_9DELT/22-112         AC W4MAZ0.1
#=GS T1AA35_9ZZZZ/47-153         AC T1AA35.1
#=GS J3QF95_PUCT1/649-735        AC J3QF95.1
#=GS Q75H30_ORYSJ/929-1020       AC Q75H30.1
#=GS H3BCK2_LATCH/33-118         AC H3BCK2.1
#=GS A0A023BWB4_9FLAO/28-127     AC A0A023BWB4.1
#=GS W1QQA7_PSEAI/67-153         AC W1QQA7.1
#=GS A7BKU9_9GAMM/1-75           AC A7BKU9.1
#=GS I9P9V0_9FLAO/29-128         AC I9P9V0.1
#=GS I1ANZ8_PSEAI/67-153         AC I1ANZ8.1
#=GS R6AY81_9BACT/569-662        AC R6AY81.1
#=GS U7YT33_BRUAO/127-216        AC U7YT33.1
#=GS H2LDN2_ORYLA/159-251        AC H2LDN2.1
#=GS W4JNH7_9HOMO/11-110         AC W4JNH7.1
#=GS K2FTE1_9BACT/6-97           AC K2FTE1.1
#=GS T0HLS1_9SPHN/105-193        AC T0HLS1.1
#=GS U5DAJ4_AMBTC/290-370        AC U5DAJ4.1
#=GS B2SGL5_FRATM/39-126         AC B2SGL5.1
#=GS B3C568_9BACE/179-275        AC B3C568.1
#=GS K7HAB1_CAEJA/303-388        AC K7HAB1.1
#=GS F4QTX2_9CAUL/182-282        AC F4QTX2.1
#=GS H2WPY2_CAEJA/160-244        AC H2WPY2.2
#=GS W2W8M3_PHYPR/5-79           AC W2W8M3.1
#=GS Q2QS25_ORYSJ/238-329        AC Q2QS25.2
#=GS J3FBH3_9PSED/67-153         AC J3FBH3.1
#=GS B0UK85_METS4/122-211        AC B0UK85.1
#=GS I4ITA9_MICAE/33-126         AC I4ITA9.1
#=GS A0A037VVY3_PSEAI/67-153     AC A0A037VVY3.1
#=GS X2H6F0_9GAMM/37-144         AC X2H6F0.1
#=GS N8HSX8_BRUSS/127-216        AC N8HSX8.1
#=GS U4DE01_9VIBR/56-149         AC U4DE01.1
#=GS G5ACP4_PHYSP/754-850        AC G5ACP4.1
#=GS Z2DPI6_PSEAI/67-153         AC Z2DPI6.1
#=GS Q2QU35_ORYSJ/296-385        AC Q2QU35.1
#=GS A0A015ZRH0_BACFG/323-416    AC A0A015ZRH0.1
#=GS H8KJ91_RICR3/126-213        AC H8KJ91.1
#=GS Q2NDV0_ERYLH/187-281        AC Q2NDV0.1
#=GS S0DZ93_GIBF5/87-176         AC S0DZ93.1
#=GS L8AIM0_BACIU/19-116         AC L8AIM0.1
#=GS L0D6X7_SINAD/47-136         AC L0D6X7.1
#=GS I9S0R3_9BACE/329-421        AC I9S0R3.1
#=GS A0A016S9U5_9BILA/470-554    AC A0A016S9U5.1
#=GS T3ZSQ0_PEPDI/15-110         AC T3ZSQ0.1
#=GS A0A017NZR3_BACFG/321-418    AC A0A017NZR3.1
#=GS U8G7W5_PSEAI/106-195        AC U8G7W5.1
#=GS A7BQU0_9GAMM/21-113         AC A7BQU0.1
#=GS T4I5J9_PEPDI/15-110         AC T4I5J9.1
#=GS I9V7V0_BACFG/203-295        AC I9V7V0.1
#=GS A4CPB5_ROBBH/50-148         AC A4CPB5.1
#=GS N8D6Q3_BRUML/127-216        AC N8D6Q3.1
#=GS U6ATH1_PSEAI/106-195        AC U6ATH1.1
#=GS U1HJP6_9BRAD/67-156         AC U1HJP6.1
#=GS U9SAU1_PSEAI/54-140         AC U9SAU1.1
#=GS A0A059FUJ2_9RHOB/193-290    AC A0A059FUJ2.1
#=GS Q01AJ1_OSTTA/283-377        AC Q01AJ1.1
#=GS Q13EE8_RHOPS/63-152         AC Q13EE8.1
#=GS N8J5Z9_BRUSS/127-216        AC N8J5Z9.1
#=GS E6PIY6_9ZZZZ/365-455        AC E6PIY6.1
#=GS F2J2S4_POLGS/59-148         AC F2J2S4.1
#=GS A5C0J9_VITVI/399-488        AC A5C0J9.1
#=GS A0A016W027_9BILA/190-277    AC A0A016W027.1
#=GS B9T325_RICCO/397-459        AC B9T325.1
#=GS I1CVT3_RHIO9/563-656        AC I1CVT3.1
#=GS G0A589_METMM/108-192        AC G0A589.1
#=GS A1YGR9_PHIRO/33-122         AC A1YGR9.1
#=GS N9WBB8_9SPHN/78-166         AC N9WBB8.1
#=GS K0D5W4_ALTMS/42-132         AC K0D5W4.1
#=GS M5TS56_STEMA/36-133         AC M5TS56.1
#=GS D5C1V5_NITHN/42-133         AC D5C1V5.1
#=GS I1C2C8_RHIO9/162-251        AC I1C2C8.1
#=GS G0PN96_CAEBE/200-285        AC G0PN96.1
#=GS G6EZL2_9PROT/194-286        AC G6EZL2.1
#=GS R5BES9_9BACE/356-449        AC R5BES9.1
#=GS I3XF06_RHIFR/67-156         AC I3XF06.1
#=GS A0A031E4M6_PSEAI/106-195    AC A0A031E4M6.1
#=GS I2L911_BURPE/33-141         AC I2L911.1
#=GS W2ZZ02_PHYPR/84-172         AC W2ZZ02.1
#=GS I1CW43_RHIO9/563-656        AC I1CW43.1
#=GS I1BHC2_RHIO9/95-183         AC I1BHC2.1
#=GS A0A015KUL2_9GLOM/3-91       AC A0A015KUL2.1
#=GS G4E2X5_9GAMM/114-202        AC G4E2X5.1
#=GS B8P600_POSPM/209-298        AC B8P600.1
#=GS W0RUZ6_9BACT/63-152         AC W0RUZ6.1
#=GS X1WZS5_ACYPI/291-382        AC X1WZS5.1
#=GS S5Z9A2_9CREN/15-99          AC S5Z9A2.1
#=GS V8HA37_RHOCA/85-173         AC V8HA37.1
#=GS F7Y6R2_MESOW/82-171         AC F7Y6R2.1
#=GS V9E8F9_PHYPR/287-383        AC V9E8F9.1
#=GS W2Y1S6_PHYPR/234-324        AC W2Y1S6.1
#=GS H8GRJ5_METAL/58-142         AC H8GRJ5.1
#=GS E6VA61_VARPE/110-197        AC E6VA61.1
#=GS A0A015T4B6_BACFG/176-268    AC A0A015T4B6.1
#=GS C6CQE3_DICZE/55-162         AC C6CQE3.1
#=GS V7G2P2_9RHIZ/81-169         AC V7G2P2.1
#=GS K6Z4C8_9ALTE/64-149         AC K6Z4C8.1
#=GS D0RH24_9RHIZ/127-216        AC D0RH24.1
#=GS I1BP65_RHIO9/121-189        AC I1BP65.1
#=GS X6JY45_9RHIZ/127-216        AC X6JY45.1
#=GS U9RK93_PSEAI/54-140         AC U9RK93.1
#=GS S6P219_PSESF/71-157         AC S6P219.1
#=GS Q2R4I1_ORYSJ/908-999        AC Q2R4I1.1
#=GS R9ZKR0_PSEAI/67-153         AC R9ZKR0.1
#=GS U9K6P5_PSEAI/54-140         AC U9K6P5.1
#=GS E3MNH1_CAERE/1114-1203      AC E3MNH1.1
#=GS X6X9I0_PSEAI/54-140         AC X6X9I0.1
#=GS B4DCL6_9BACT/411-504        AC B4DCL6.1
#=GS J8B4W0_BACCE/21-110         AC J8B4W0.1
#=GS K5UNV7_PHACS/677-768        AC K5UNV7.1
#=GS E3E8M3_PAEPS/14-107         AC E3E8M3.1
#=GS A0A016BEU2_BACFG/187-280    AC A0A016BEU2.1
#=GS S7X1G5_9FLAO/28-127         AC S7X1G5.1
#=GS U5C3G5_9BACT/197-294        AC U5C3G5.1
#=GS F7T8U6_ALCXX/207-300        AC F7T8U6.1
#=GS F4QUZ8_BREDI/80-175         AC F4QUZ8.1
#=GS E4VWM4_BACFG/176-272        AC E4VWM4.1
#=GS G3HXL2_CRIGR/114-204        AC G3HXL2.1
#=GS J9KQ51_ACYPI/144-234        AC J9KQ51.2
#=GS Q2QPT5_ORYSJ/967-1058       AC Q2QPT5.1
#=GS U3VET9_PEPDI/208-305        AC U3VET9.1
#=GS Q8YXQ8_NOSS1/237-324        AC Q8YXQ8.1
#=GS K7I327_CAEJA/274-358        AC K7I327.1
#=GS H0SNB8_9BRAD/66-155         AC H0SNB8.1
#=GS I4G6D6_MICAE/27-115         AC I4G6D6.1
#=GS X7EHN7_9RHOB/87-175         AC X7EHN7.1
#=GS D7EKC0_TRICA/417-508        AC D7EKC0.1
#=GS Q8G158_BRUSU/127-216        AC Q8G158.1
#=GS T0GAP5_9SPHN/1-85           AC T0GAP5.1
#=GS X0EPK1_FUSOX/1002-1097      AC X0EPK1.1
#=GS S6A3B4_9SPIO/312-407        AC S6A3B4.1
#=GS A0A016KU10_BACFG/187-280    AC A0A016KU10.1
#=GS H5T8T1_9ALTE/279-370        AC H5T8T1.1
#=GS Q92P96_RHIME/126-215        AC Q92P96.1
#=GS Q1MMV9_RHIL3/70-159         AC Q1MMV9.1
#=GS G7VGI3_9CREN/8-94           AC G7VGI3.1
#=GS Q7XMR5_ORYSJ/207-298        AC Q7XMR5.1
#=GS L8K5W9_9FLAO/43-141         AC L8K5W9.1
#=GS E3MUM1_CAERE/358-443        AC E3MUM1.1
#=GS S8ED43_FOMPI/4-94           AC S8ED43.1
#=GS U8AI59_PSEAI/106-195        AC U8AI59.1
#=GS D6WF16_TRICA/447-534        AC D6WF16.1
#=GS J3EQL6_9PSED/67-153         AC J3EQL6.1
#=GS R0D5L9_CAUCE/203-304        AC R0D5L9.1
#=GS G8R7Y6_OWEHD/209-303        AC G8R7Y6.1
#=GS U9LB12_PSEAI/106-195        AC U9LB12.1
#=GS F1Z554_9SPHN/73-161         AC F1Z554.1
#=GS R4GBR2_ANOCA/526-622        AC R4GBR2.1
#=GS S7PR02_GLOTA/666-755        AC S7PR02.1
#=GS M7N538_9BACT/125-226        AC M7N538.1
#=GS U6LSJ2_9EIME/173-258        AC U6LSJ2.1
#=GS C3QDT2_9BACE/39-132         AC C3QDT2.1
#=GS G0NQE6_CAEBE/745-840        AC G0NQE6.1
#=GS F8CNL1_MYXFH/245-337        AC F8CNL1.1
#=GS K0NMA0_DESTT/155-249        AC K0NMA0.1
#=GS V9V3V5_9PSED/66-152         AC V9V3V5.1
#=GS X1IPR5_9ZZZZ/41-123         AC X1IPR5.1
#=GS A0A031I5F6_9SPHN/186-275    AC A0A031I5F6.1
#=GS U9UWX1_RHIID/1-81           AC U9UWX1.1
#=GS H0T3U0_9BRAD/57-146         AC H0T3U0.1
#=GS I4HNR2_MICAE/41-137         AC I4HNR2.1
#=GS J4KEF5_9BACT/43-132         AC J4KEF5.1
#=GS L7MA76_9ACAR/17-104         AC L7MA76.1
#=GS E2LZH6_MONPE/321-394        AC E2LZH6.1
#=GS C9YH62_9BURK/96-183         AC C9YH62.1
#=GS U9LQQ7_PSEAI/54-140         AC U9LQQ7.1
#=GS E3MN92_CAERE/589-663        AC E3MN92.1
#=GS H5Y7K3_9BRAD/62-151         AC H5Y7K3.1
#=GS G7YC68_CLOSI/278-366        AC G7YC68.1
#=GS S6XDY4_PSESF/71-157         AC S6XDY4.1
#=GS F4XN23_9CYAN/75-160         AC F4XN23.1
#=GS F0GV38_9FIRM/19-113         AC F0GV38.1
#=GS R7E1J5_9BACT/42-130         AC R7E1J5.1
#=GS E3NH57_CAERE/1603-1689      AC E3NH57.1
#=GS C5LEI9_PERM5/610-702        AC C5LEI9.1
#=GS B6VWU1_9BACE/20-114         AC B6VWU1.1
#=GS R7HTU6_9BACT/557-650        AC R7HTU6.1
#=GS A0LZP6_GRAFK/53-146         AC A0LZP6.1
#=GS A5BRN4_VITVI/352-443        AC A5BRN4.1
#=GS N7V119_BRUAO/127-216        AC N7V119.1
#=GS K7X629_9RETR/92-140         AC K7X629.1
#=GS B0CLI9_BRUSI/127-216        AC B0CLI9.1
#=GS W2XHP1_PHYPR/397-487        AC W2XHP1.1
#=GS S6I914_9PSED/67-153         AC S6I914.1
#=GS Q0G4P5_9RHIZ/76-165         AC Q0G4P5.1
#=GS A5AQ76_VITVI/355-446        AC A5AQ76.1
#=GS Q0BX44_HYPNA/184-281        AC Q0BX44.1
#=GS D5BZZ1_NITHN/124-218        AC D5BZZ1.1
#=GS Q1JY80_DESAC/96-190         AC Q1JY80.1
#=GS D6WD79_TRICA/333-421        AC D6WD79.1
#=GS A0A016S140_9BILA/648-726    AC A0A016S140.1
#=GS A0A010RET9_9PEZI/106-196    AC A0A010RET9.1
#=GS G4LG78_PSEAI/54-140         AC G4LG78.1
#=GS W2XQK2_PHYPR/28-116         AC W2XQK2.1
#=GS N1WRU2_9FLAO/35-128         AC N1WRU2.1
#=GS H8N5Y4_RICPO/126-213        AC H8N5Y4.1
#=GS R5BFS6_9BACT/46-139         AC R5BFS6.1
#=GS K7GVS2_CAEJA/324-396        AC K7GVS2.1
#=GS V4A8E1_LOTGI/293-381        AC V4A8E1.1
#=GS U6L9V7_9EIME/205-293        AC U6L9V7.1
#=GS Q6UUJ4_ORYSJ/435-521        AC Q6UUJ4.1
#=GS U9W945_9CYAN/190-275        AC U9W945.1
#=GS W4FC23_9STRA/979-1066       AC W4FC23.1
#=GS H0PWH6_9RHOO/105-192        AC H0PWH6.1
#=GS X5PC37_9RHIZ/81-169         AC X5PC37.1
#=GS S3LID1_TREDN/166-263        AC S3LID1.1
#=GS M1YDC4_PSEAI/106-195        AC M1YDC4.1
#=GS U6LNX6_9EIME/113-201        AC U6LNX6.1
#=GS J7VSL3_STEMA/188-286        AC J7VSL3.1
#=GS K6XWJ0_9ALTE/287-379        AC K6XWJ0.1
#=GS H1W879_9CYAN/34-116         AC H1W879.1
#=GS U2ZPD5_PSEAC/1-81           AC U2ZPD5.1
#=GS W2LDG4_PHYPR/63-152         AC W2LDG4.1
#=GS A0A017NZR3_BACFG/187-280    AC A0A017NZR3.1
#=GS V2Y9V9_MONRO/6-98           AC V2Y9V9.1
#=GS A6V054_PSEA7/106-195        AC A6V054.1
#=GS T0IZ90_9SPHN/49-137         AC T0IZ90.1
#=GS U8IXH6_PSEAI/106-195        AC U8IXH6.1
#=GS S6D5V9_ACEPA/193-286        AC S6D5V9.1
#=GS W4ZCM6_STRPU/394-489        AC W4ZCM6.1
#=GS Q53RL5_ORYSJ/1172-1263      AC Q53RL5.1
#=GS U8SUZ1_PSEAI/106-195        AC U8SUZ1.1
#=GS A0A016HR59_BACFG/176-268    AC A0A016HR59.1
#=GS U6RTD7_9BACE/562-655        AC U6RTD7.1
#=GS K9V6E9_9CYAN/74-160         AC K9V6E9.1
#=GS T3BUC7_PEPDI/15-110         AC T3BUC7.1
#=GS U9IX04_PSEAI/106-195        AC U9IX04.1
#=GS F6CLH6_DESK7/6-94           AC F6CLH6.1
#=GS A0A030WDC9_PSEAI/106-195    AC A0A030WDC9.1
#=GS H8NBC9_RICPO/126-213        AC H8NBC9.1
#=GS G7FIL1_9GAMM/21-117         AC G7FIL1.1
#=GS E4T634_PALPW/66-159         AC E4T634.1
#=GS W2HEJ7_PHYPR/70-161         AC W2HEJ7.1
#=GS S7MW27_MYOBR/114-204        AC S7MW27.1
#=GS I1BZU3_RHIO9/310-398        AC I1BZU3.1
#=GS A5BAW2_VITVI/397-488        AC A5BAW2.1
#=GS Q6AVG0_ORYSJ/703-794        AC Q6AVG0.1
#=GS C9ULP2_BRUAO/127-216        AC C9ULP2.1
#=GS U8L0B2_PSEAI/106-195        AC U8L0B2.1
#=GS F5Z816_ALTSS/205-299        AC F5Z816.1
#=GS H2N051_ORYLA/159-253        AC H2N051.1
#=GS Q01KN2_ORYSA/461-553        AC Q01KN2.1
#=GS K9CY97_SPHYA/113-201        AC K9CY97.1
#=GS V8AID6_RHOCA/85-173         AC V8AID6.1
#=GS T1D6N2_GLUTH/194-281        AC T1D6N2.1
#=GS A0A022NKV3_PSEAI/54-140     AC A0A022NKV3.1
#=GS G4ZA02_PHYSP/823-914        AC G4ZA02.1
#=GS K7HIB0_CAEJA/497-592        AC K7HIB0.1
#=GS V9Y6V5_BURPE/69-177         AC V9Y6V5.1
#=GS Q2SKS1_HAHCH/86-173         AC Q2SKS1.1
#=GS L1QAL7_BREDI/195-288        AC L1QAL7.1
#=GS N1MLJ3_9SPHN/45-133         AC N1MLJ3.1
#=GS I5C5G0_9BACT/37-137         AC I5C5G0.1
#=GS F3WSZ5_9SPHN/83-171         AC F3WSZ5.1
#=GS R9F0V9_YEREN/49-149         AC R9F0V9.1
#=GS G8NYF5_GRAMM/197-304        AC G8NYF5.1
#=GS A0A024K8I7_9RHIZ/121-210    AC A0A024K8I7.1
#=GS E5URR5_9BACE/561-654        AC E5URR5.1
#=GS K9UWI5_9CYAN/41-136         AC K9UWI5.1
#=GS A0A059G815_9RHOB/190-287    AC A0A059G815.1
#=GS Q8YTZ0_NOSS1/85-171         AC Q8YTZ0.1
#=GS I1BIG4_RHIO9/47-136         AC I1BIG4.1
#=GS F2J600_POLGS/130-219        AC F2J600.1
#=GS N7PS07_BRUOV/127-216        AC N7PS07.1
#=GS A3J7B3_9FLAO/49-142         AC A3J7B3.1
#=GS W4XNR8_STRPU/434-554        AC W4XNR8.1
#=GS N8M4E0_BRUOV/127-216        AC N8M4E0.1
#=GS Q7XMR7_ORYSJ/587-683        AC Q7XMR7.1
#=GS W2Y0P2_PHYPR/820-911        AC W2Y0P2.1
#=GS V6V9R4_9BACI/14-107         AC V6V9R4.1
#=GS Q6NCD8_RHOPA/66-155         AC Q6NCD8.1
#=GS V6GAY5_9LEPT/69-157         AC V6GAY5.1
#=GS K7HLC5_CAEJA/347-431        AC K7HLC5.1
#=GS W4LI33_9DELT/98-188         AC W4LI33.1
#=GS C6X9M2_METGS/107-195        AC C6X9M2.1
#=GS M5C8G5_THACB/401-493        AC M5C8G5.1
#=GS J3PPD7_PUCT1/340-421        AC J3PPD7.1
#=GS K0CMV9_ALTME/168-275        AC K0CMV9.1
#=GS S5XRV7_PARAH/85-173         AC S5XRV7.1
#=GS V4P5J4_9CAUL/214-315        AC V4P5J4.1
#=GS D7EKB8_TRICA/458-549        AC D7EKB8.1
#=GS F4C5H2_SPHS2/193-289        AC F4C5H2.1
#=GS W2VPR3_PHYPR/108-201        AC W2VPR3.1
#=GS W6NC71_HAECO/352-436        AC W6NC71.1
#=GS E3MIN4_CAERE/420-491        AC E3MIN4.1
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W6SE82_9CYAN/72-158                    ......................................vl--ATF....N..D......S.qPF...PMMIDT..GAS..G...T.VIT...P.L...M..A.......EV.L................GV..VR...TG.R..-...--.......GL..A.....NT........P......S..E..........Q.....nV...E..F....DL.....G...E.II......S...........I..E..V......GG...........A...M....AS..N.L........T..........V..AIAP......................................-.-.....A.....LE...........V.......GL......LGQDF...........................................................................
K5YG10_FRATL/191-289                   .......................................m-PITV....N..N......N.sPV...NCLVDT..GTS..N...F.TIS...N.N...Y..S.......ES.L................GL..KS...TS.K..-...--.......KT..I.....QA........T......D..G..........T......L...T..I....AD.....A...N.IS......S...........L..I..I......NP...........-...-....--..-.-........-..........-..----......................................-.-.....-.....--...........-.......--......-----lniffqkkvkldnisatsaniepmskflgvlcvlgy.......................................
B2S598_BRUA1/127-216                   ........................................VNGRV....N..G......A..RV...HFLVDT..GAS..S...V.VLS...Q.E...D..A.......ER.A................GI..DT...AS.L..N...YS.......VP..I.....MT........A......N..G..........Q......A...R..A....AS.....I...T.IA......T...........L..Q..I......GD...........I...E....RH..N.V........R..........A..MVTK......................................E.G.....L.....LT...........G.......SL......LGMNF...........................................................................
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