GenomeNet

Database: Pfam
Entry: AvrPphF-ORF-2
LinkDB: AvrPphF-ORF-2
Original site: AvrPphF-ORF-2 
#=GF ID   AvrPphF-ORF-2
#=GF AC   PF09143.8
#=GF DE   AvrPphF-ORF-2
#=GF AU   Sammut SJ
#=GF SE   pdb_1s21
#=GF GA   25.00 25.00;
#=GF TC   40.10 60.30;
#=GF NC   19.90 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   15341731
#=GF RT   Crystal structures of the type III effector protein AvrPphF and
#=GF RT   its chaperone reveal residues required for plant pathogenesis. 
#=GF RA   Singer AU, Desveaux D, Betts L, Chang JH, Nimchuk Z, Grant SR,
#=GF RA   Dangl JL, Sondek J; 
#=GF RL   Structure. 2004;12:1669-1681.
#=GF DR   INTERPRO; IPR015226;
#=GF DR   SCOP; 1s21; fa;
#=GF CC   Members of this family of plant pathogenic proteins adopt an
#=GF CC   elongated structure somewhat reminiscent of a mushroom that can
#=GF CC   be divided into 'stalk' and 'head' subdomains. The stalk
#=GF CC   subdomain is composed of the N-terminal helix (alpha1) and beta
#=GF CC   strands beta3-beta4. An antiparallel beta sheet (beta5,
#=GF CC   beta7-beta8) forms the base of the head subdomain that interacts
#=GF CC   with the stalk. A pair of twisted antiparallel beta sheets
#=GF CC   (beta1 and beta6; beta2 and beta9/9') supported by alpha2 form
#=GF CC   the dome of the head. The head subdomain possesses weak
#=GF CC   structural similarity with the catalytic portion of a number of
#=GF CC   ADP-ribosyltransferase toxins [1].
#=GF SQ   3
#=GS Q88A90_PSESM/29-204   AC Q88A90.1
#=GS A1TRM9_ACIAC/83-173   AC A1TRM9.1
#=GS Q8XRK9_RALSO/152-338  AC Q8XRK9.2
Q88A90_PSESM/29-204              .......STHVGGDTLTSIHQLSHSQREQFLNMHDPMRVMGLDHDTELFRTTDSRYI....KNDKLAGNPQSMASILMHEELRPNR.FASH..TGAQPHEAR.........AYVPKRIKATDLGVPSLNVMTGSLARDGIRAYDHmSDNQVSVKMRLGDFLERGGKVYADASSVADDGETSQALIVTLPKGQKVPVERV..............
A1TRM9_ACIAC/83-173              yvlkngr-------VFPSVNTLPPAERAAFLKKHDPCSQLKLNDDSVFFRVTERQWV....QDGTLSGHPQSGARIRNHFAIAENP.YM--..---------.........----------------------------------.-----------------------------------------------------pgsfkpaemdamhl
Q8XRK9_RALSO/152-338             .assppy---------IPVDALPPPLSKAFLEAFDPIRSLGLTDQSVFYRALASRYLladgHQMKLAGNPRSGAYVRHHHRLLPSSgLASRetFESLPATARermlndpmqQYEWVRMRARDLPEPSLNVMFGVHAEAGARSYAK.TSDHVVVSMTFGDLRKAGGQVFLDTRA-SAGSDHTKALIVTLPKGRTVPVKII..............
#=GC seq_cons                    .s.pssh.......shsSVcsLPPupRcAFLctHDPhRsLGLsDDSVFFRsT-SRYl....+ssKLAGNPQSGApIRpHacLtPNs.aAS+..htu.PtpAR.........tY..hRh+ApDLs.PSLNVMhGshAcsGhRuYs+.osspVsVpMphGDhhctGGpVahDspu.ussu-popALIVTLPKGppVPVchl..............
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