#=GF ID Bacillus_PapR
#=GF AC PF05968.10
#=GF DE Bacillus PapR protein
#=GF AU Moxon SJ
#=GF SE Pfam-B_4892 (release 9.0)
#=GF GA 21.10 21.10;
#=GF TC 21.20 36.30;
#=GF NC 20.30 18.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 12198157
#=GF RT A cell-cell signaling peptide activates the PlcR virulence
#=GF RT regulon in bacteria of the Bacillus cereus group.
#=GF RA Slamti L, Lereclus D;
#=GF RL EMBO J 2002;21:4550-4559.
#=GF DR INTERPRO; IPR009239;
#=GF CC This family consists of the Bacillus species specific PapR
#=GF CC protein. The papR gene belongs to the PlcR regulon and is
#=GF CC located 70 bp downstream from plcR. It encodes a 48-amino-acid
#=GF CC peptide. Disruption of the papR gene abolishes expression of the
#=GF CC PlcR regulon, resulting in a large decrease in haemolysis and
#=GF CC virulence in insect larvae. A processed form of PapR activates
#=GF CC the PlcR regulon by allowing PlcR to bind to its DNA target.
#=GF CC This activating mechanism is strain specific [1].
#=GF SQ 4
#=GS C2X4E2_BACCE/1-48 AC C2X4E2.1
#=GS Q9XCQ7_BACAN/1-48 AC Q9XCQ7.1
#=GS Q814S3_BACCR/1-48 AC Q814S3.1
#=GS A7GV97_BACCN/1-45 AC A7GV97.1
C2X4E2_BACCE/1-48 MKKLLIGSLLTLAMAWGISLGDIALEKSQIISHNDQEVQLAQEVPYEY.
Q9XCQ7_BACAN/1-48 MKKLLIGSLLTLAMAWGISLGDTALEKNQVISHNDQEVQLASDVPFEY.
Q814S3_BACCR/1-48 MKKLLIGSLLTLAMAWGISLGDTALEKSHIISHNDQEVQLAKDLPFEY.
A7GV97_BACCN/1-45 MKKFLACSLVAVAMLAGVAFG---VGQDQALTNQQEEVQLASDLPFE-h
#=GC seq_cons MKKLLIGSLLTLAMAWGISLGDhALEKsQlISHNDQEVQLApDlPFEY.
//