GenomeNet

Database: Pfam
Entry: Bin3
LinkDB: Bin3
Original site: Bin3 
#=GF ID   Bin3
#=GF AC   PF06859.7
#=GF DE   Bicoid-interacting protein 3 (Bin3)
#=GF AU   Vella Briffa B
#=GF SE   Pfam-B_5564 (release 10.0)
#=GF GA   21.00 21.00;
#=GF TC   21.20 21.10;
#=GF NC   20.90 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10717484
#=GF RT   Identification of drosophila bicoid-interacting proteins using a
#=GF RT   custom two-hybrid selection. 
#=GF RA   Zhu W, Hanes SD; 
#=GF RL   Gene 2000;245:329-339.
#=GF DR   INTERPRO; IPR010675;
#=GF CC   This family represents a conserved region of approximately 120
#=GF CC   residues within eukaryotic Bicoid-interacting protein 3 (Bin3).
#=GF CC   Bin3, which shows similarity to a number of protein
#=GF CC   methyltransferases that modify RNA-binding proteins, interacts
#=GF CC   with Bicoid, which itself directs pattern formation in the early
#=GF CC   Drosophila embryo. The interaction might allow Bicoid to switch
#=GF CC   between its dual roles in transcription and translation [1].
#=GF CC   Note that family members contain a conserved HLN motif.
#=GF SQ   294
#=GS F7EXI4_MACMU/574-683    AC F7EXI4.1
#=GS B4LZ69_DROVI/222-331    AC B4LZ69.1
#=GS H9L3R8_CHICK/161-243    AC H9L3R8.1
#=GS E6ZF28_DICLA/143-250    AC E6ZF28.1
#=GS B3L5R2_PLAKH/300-419    AC B3L5R2.1
#=GS C6F7A5_PSEMZ/82-106     AC C6F7A5.1
#=GS Q6NPC9_ARATH/209-318    AC Q6NPC9.1
#=GS H2WN39_CAEJA/238-346    AC H2WN39.1
#=GS C6F7B0_PSEMZ/82-106     AC C6F7B0.1
#=GS B6JVZ4_SCHJY/205-263    AC B6JVZ4.1
#=GS B3KP86_HUMAN/105-214    AC B3KP86.1
#=GS Q7T0L7_XENLA/143-242    AC Q7T0L7.1
#=GS H0XA29_OTOGA/158-251    AC H0XA29.1
#=GS G7L862_MEDTR/184-293    AC G7L862.1
#=GS B4JUG9_DROGR/210-319    AC B4JUG9.1
#=GS G4TL58_PIRID/213-315    AC G4TL58.1
#=GS F1KVT1_ASCSU/419-527    AC F1KVT1.1
#=GS B0W1L8_CULQU/659-768    AC B0W1L8.1
#=GS C6F798_PSEMZ/82-106     AC C6F798.1
#=GS C5KGT0_PERM5/244-356    AC C5KGT0.1
#=GS H2PLN2_PONAB/105-214    AC H2PLN2.1
#=GS H0XUS6_OTOGA/143-237    AC H0XUS6.1
#=GS G7MNU3_MACMU/443-551    AC G7MNU3.1
#=GS Q5R619_PONAB/105-214    AC Q5R619.1
#=GS G9KAB5_MUSPF/557-666    AC G9KAB5.1
#=GS D7TBJ3_VITVI/177-286    AC D7TBJ3.1
#=GS G8F4G3_MACFA/427-535    AC G8F4G3.1
#=GS E2QC61_DROME/1003-1112  AC E2QC61.1
#=GS H3GI20_PHYRM/237-345    AC H3GI20.1
#=GS H9KPT2_APIME/134-243    AC H9KPT2.1
#=GS Q29ED3_DROPS/130-235    AC Q29ED3.1
#=GS C6F796_PSEMZ/82-106     AC C6F796.1
#=GS G3I651_CRIGR/358-467    AC G3I651.1
#=GS H0XH66_OTOGA/561-670    AC H0XH66.1
#=GS A8JDX0_CHLRE/163-273    AC A8JDX0.1
#=GS F6TDY8_MONDO/159-259    AC F6TDY8.1
#=GS E2BW52_HARSA/922-1031   AC E2BW52.1
#=GS A8E7D2_DANRE/127-234    AC A8E7D2.1
#=GS F4WT37_ACREC/499-607    AC F4WT37.1
#=GS Q4RIJ9_TETNG/133-239    AC Q4RIJ9.1
#=GS H2QV26_PANTR/574-683    AC H2QV26.1
#=GS B4H1V6_DROPE/130-235    AC B4H1V6.1
#=GS D7MQX7_ARALL/204-313    AC D7MQX7.1
#=GS E3LRN2_CAERE/267-375    AC E3LRN2.1
#=GS A9SNK5_PHYPA/235-344    AC A9SNK5.1
#=GS D5GLM2_TUBMM/143-250    AC D5GLM2.1
#=GS D3BBS5_POLPA/347-456    AC D3BBS5.1
#=GS B4PHU8_DROYA/133-238    AC B4PHU8.1
#=GS D8SHL2_SELML/165-274    AC D8SHL2.1
#=GS Q5I0E0_RAT/214-323      AC Q5I0E0.1
#=GS A5K5B5_PLAVS/318-411    AC A5K5B5.1
#=GS C6F7A6_PSEMZ/82-106     AC C6F7A6.1
#=GS B4KWS9_DROMO/136-241    AC B4KWS9.1
#=GS BN3D2_MOUSE/158-245     AC Q91YP1.1
#=GS F7H083_CALJA/157-246    AC F7H083.1
#=GS B4QD82_DROSI/1004-1113  AC B4QD82.1
#=GS C1E1J2_MICSR/268-380    AC C1E1J2.1
#=GS E2A668_CAMFO/457-566    AC E2A668.1
#=GS E2A3K2_CAMFO/134-241    AC E2A3K2.1
#=GS Q016F6_OSTTA/181-298    AC Q016F6.1
#=GS H2PLN1_PONAB/573-682    AC H2PLN1.1
#=GS B0WI06_CULQU/687-796    AC B0WI06.1
#=GS C6F7A1_PSEMZ/82-106     AC C6F7A1.1
#=GS G4YH69_PHYSP/257-363    AC G4YH69.1
#=GS C6F7B3_9CONI/82-106     AC C6F7B3.1
#=GS H0Z120_TAEGU/82-183     AC H0Z120.1
#=GS G1DG08_CAPHI/105-214    AC G1DG08.1
#=GS A8QAZ0_MALGO/176-259    AC A8QAZ0.1
#=GS A8K5Q1_HUMAN/574-683    AC A8K5Q1.1
#=GS C6F7A3_PSEMZ/82-106     AC C6F7A3.1
#=GS B3LZX5_DROAN/130-235    AC B3LZX5.1
#=GS B4HU55_DROSE/133-238    AC B4HU55.1
#=GS I1CMA2_RHIO9/154-262    AC I1CMA2.1
#=GS G3NQ71_GASAC/128-234    AC G3NQ71.1
#=GS H2RW25_TAKRU/445-555    AC H2RW25.1
#=GS Q9LU61_ARATH/270-379    AC Q9LU61.1
#=GS D2V086_NAEGR/322-445    AC D2V086.1
#=GS E3X8N0_ANODA/787-897    AC E3X8N0.1
#=GS C6F7A9_PSEMZ/82-106     AC C6F7A9.1
#=GS A7SJ10_NEMVE/155-264    AC A7SJ10.1
#=GS B4H643_DROPE/1095-1204  AC B4H643.1
#=GS A2YXL5_ORYSI/198-318    AC A2YXL5.1
#=GS I1QLD6_ORYGL/194-303    AC I1QLD6.1
#=GS B0D6P1_LACBS/146-238    AC B0D6P1.1
#=GS B4II51_DROSE/1001-1110  AC B4II51.1
#=GS D4ABH7_RAT/158-246      AC D4ABH7.1
#=GS B3NC30_DROER/133-238    AC B3NC30.1
#=GS I1KPY6_SOYBN/167-276    AC I1KPY6.1
#=GS E2RGJ1_CANFA/566-675    AC E2RGJ1.1
#=GS E5A0R6_LEPMJ/359-462    AC E5A0R6.1
#=GS B6HG65_PENCW/127-220    AC B6HG65.1
#=GS H9HZB6_ATTCE/60-124     AC H9HZB6.1
#=GS BN3D2_PONAB/157-252     AC Q5RFI3.1
#=GS B4I463_DROSE/285-394    AC B4I463.1
#=GS Q7PZU2_ANOGA/651-760    AC Q7PZU2.4
#=GS Q297L6_DROPS/194-303    AC Q297L6.2
#=GS B3LWF0_DROAN/196-305    AC B3LWF0.1
#=GS D0MZS5_PHYIT/254-360    AC D0MZS5.1
#=GS B4LGW8_DROVI/134-239    AC B4LGW8.1
#=GS E9JD11_SOLIN/456-564    AC E9JD11.1
#=GS B2WHX3_PYRTR/134-237    AC B2WHX3.1
#=GS C6F7A8_PSEMZ/82-106     AC C6F7A8.1
#=GS G1S803_NOMLE/157-250    AC G1S803.1
#=GS D0NPB1_PHYIT/191-299    AC D0NPB1.1
#=GS Q6XHG4_DROYA/133-176    AC Q6XHG4.1
#=GS H9GHU6_ANOCA/530-639    AC H9GHU6.1
#=GS B7PJP2_IXOSC/456-565    AC B7PJP2.1
#=GS Q5TXE3_ANOGA/179-288    AC Q5TXE3.3
#=GS H2V1G6_TAKRU/429-537    AC H2V1G6.1
#=GS B5DU34_DROPS/1164-1273  AC B5DU34.1
#=GS I1I943_BRADI/207-316    AC I1I943.1
#=GS G1TJW0_RABIT/561-670    AC G1TJW0.1
#=GS B4QQK8_DROSI/133-238    AC B4QQK8.1
#=GS D8QDP5_SCHCM/162-286    AC D8QDP5.1
#=GS H3BF65_LATCH/159-266    AC H3BF65.1
#=GS E2B3M0_HARSA/138-203    AC E2B3M0.1
#=GS BN3D1_DROME/1003-1112   AC Q7K480.1
#=GS Q23GA7_TETTS/467-578    AC Q23GA7.1
#=GS F1QE64_DANRE/414-522    AC F1QE64.1
#=GS C6F799_PSEMZ/82-106     AC C6F799.1
#=GS E9C876_CAPO3/348-458    AC E9C876.1
#=GS B3NB62_DROER/1007-1116  AC B3NB62.1
#=GS E4Y7R0_OIKDI/246-353    AC E4Y7R0.1
#=GS G3TKP3_LOXAF/158-258    AC G3TKP3.1
#=GS H3GJA5_PHYRM/254-359    AC H3GJA5.1
#=GS F2EIF4_HORVD/210-319    AC F2EIF4.1
#=GS E6ZLK6_SPORE/258-364    AC E6ZLK6.1
#=GS G7PI92_MACFA/157-246    AC G7PI92.1
#=GS F2U8A7_SALS5/157-222    AC F2U8A7.1
#=GS B4QXI9_DROSI/196-305    AC B4QXI9.1
#=GS Q0IG46_AEDAE/688-797    AC Q0IG46.1
#=GS F6XIE4_MOUSE/58-167     AC F6XIE4.1
#=GS C0MJ20_DROME/190-299    AC C0MJ20.1
#=GS C1MKI3_MICPC/275-371    AC C1MKI3.1
#=GS H2LR63_ORYLA/142-249    AC H2LR63.1
#=GS C6F7A2_PSEMZ/82-106     AC C6F7A2.1
#=GS F4WP52_ACREC/142-209    AC F4WP52.1
#=GS H2VCX5_TAKRU/135-241    AC H2VCX5.1
#=GS E3XB59_ANODA/1085-1157  AC E3XB59.1
#=GS A4RSG9_OSTLU/108-223    AC A4RSG9.1
#=GS G5AN29_HETGA/482-591    AC G5AN29.1
#=GS Q4SFJ1_TETNG/470-539    AC Q4SFJ1.1
#=GS B3MJ56_DROAN/1032-1141  AC B3MJ56.1
#=GS B4NYT6_DROYA/1005-1114  AC B4NYT6.1
#=GS H9KCM8_APIME/142-249    AC H9KCM8.1
#=GS E0VAV2_PEDHC/632-741    AC E0VAV2.1
#=GS G3QRK4_GORGO/574-683    AC G3QRK4.1
#=GS C6F7A0_PSEMZ/73-97      AC C6F7A0.1
#=GS F1QAZ2_DANRE/112-219    AC F1QAZ2.1
#=GS E2LJJ6_MONPE/31-82      AC E2LJJ6.1
#=GS H9JVI7_BOMMO/131-243    AC H9JVI7.1
#=GS B9PI44_TOXGO/469-566    AC B9PI44.1
#=GS B9ILR2_POPTR/212-321    AC B9ILR2.1
#=GS G0MZ23_CAEBE/264-372    AC G0MZ23.1
#=GS Q4XED7_PLACH/118-136    AC Q4XED7.1
#=GS B0W3M2_CULQU/179-290    AC B0W3M2.1
#=GS H3CXF7_TETNG/401-509    AC H3CXF7.1
#=GS G7YHB8_CLOSI/373-478    AC G7YHB8.1
#=GS G4ZR14_PHYSP/195-303    AC G4ZR14.1
#=GS A8PFD8_BRUMA/395-515    AC A8PFD8.1
#=GS E9HI70_DAPPU/131-239    AC E9HI70.1
#=GS G4VDU5_SCHMA/327-432    AC G4VDU5.1
#=GS Q4PGH9_USTMA/376-482    AC Q4PGH9.1
#=GS Q4R3R7_MACFA/106-215    AC Q4R3R7.1
#=GS G1SFM5_RABIT/158-255    AC G1SFM5.1
#=GS A2RVW3_DROPS/1159-1268  AC A2RVW3.2
#=GS MEPCE_MOUSE/551-660     AC Q8K3A9.2
#=GS H3DQW6_TETNG/1-102      AC H3DQW6.1
#=GS C6F7A7_PSEMZ/82-106     AC C6F7A7.1
#=GS F6WC50_HORSE/157-252    AC F6WC50.1
#=GS F6R6T5_MONDO/562-671    AC F6R6T5.1
#=GS C6F7B1_PSEMZ/82-106     AC C6F7B1.1
#=GS B6KD62_TOXGO/469-566    AC B6KD62.1
#=GS B3RLM9_TRIAD/195-295    AC B3RLM9.1
#=GS G3N867_GASAC/223-326    AC G3N867.1
#=GS G3V656_RAT/545-654      AC G3V656.1
#=GS C0MJ21_DROME/190-299    AC C0MJ21.1
#=GS D1GXX3_DROAN/196-305    AC D1GXX3.1
#=GS H0VMW4_CAVPO/132-229    AC H0VMW4.1
#=GS A8PCE2_COPC7/195-314    AC A8PCE2.2
#=GS D5AAQ7_PICSI/70-179     AC D5AAQ7.1
#=GS G5AU11_HETGA/168-266    AC G5AU11.1
#=GS B4N478_DROWI/133-238    AC B4N478.1
#=GS F0W384_9STRA/273-320    AC F0W384.1
#=GS H3J339_STRPU/481-567    AC H3J339.1
#=GS D2HX16_AILME/515-624    AC D2HX16.1
#=GS A3KQ55_DANRE/587-695    AC A3KQ55.1
#=GS E5S6E5_TRISP/397-506    AC E5S6E5.1
#=GS H0VXF6_CAVPO/471-580    AC H0VXF6.1
#=GS F1R4M0_DANRE/329-437    AC F1R4M0.1
#=GS H2Q5V9_PANTR/157-250    AC H2Q5V9.1
#=GS F1R5Z5_DANRE/514-622    AC F1R5Z5.1
#=GS B4KCB5_DROMO/205-314    AC B4KCB5.1
#=GS C6F7B2_PSEMZ/82-106     AC C6F7B2.1
#=GS B7P3N1_IXOSC/130-237    AC B7P3N1.1
#=GS G7E3Y2_MIXOS/989-1103   AC G7E3Y2.1
#=GS A8WFR5_DANRE/329-437    AC A8WFR5.1
#=GS G4VDU4_SCHMA/202-307    AC G4VDU4.1
#=GS G1PE92_MYOLU/565-674    AC G1PE92.1
#=GS F0VJ74_NEOCL/471-558    AC F0VJ74.1
#=GS F6V4K7_CALJA/105-214    AC F6V4K7.1
#=GS F6VWX5_MONDO/545-654    AC F6VWX5.1
#=GS BN3D2_HUMAN/157-250     AC Q7Z5W3.1
#=GS F4PUL7_DICFS/299-408    AC F4PUL7.1
#=GS G3WAE2_SARHA/1212-1321  AC G3WAE2.1
#=GS F1RMY9_PIG/575-684      AC F1RMY9.1
#=GS E1Z513_CHLVA/425-539    AC E1Z513.1
#=GS A4IG11_DANRE/203-311    AC A4IG11.1
#=GS BN3D2_DROME/190-299     AC Q9VNH1.2
#=GS C5YHA3_SORBI/197-306    AC C5YHA3.1
#=GS G1KHR3_ANOCA/155-239    AC G1KHR3.1
#=GS Q174R7_AEDAE/174-283    AC Q174R7.1
#=GS F7AZ70_CIOIN/48-157     AC F7AZ70.2
#=GS F2UBU0_SALS5/793-899    AC F2UBU0.1
#=GS C3XPI0_BRAFL/77-186     AC C3XPI0.1
#=GS B4NLC1_DROWI/194-303    AC B4NLC1.1
#=GS Q498W0_DANRE/111-219    AC Q498W0.1
#=GS G3QKH1_GORGO/79-179     AC G3QKH1.1
#=GS Q9VZD2_DROME/133-238    AC Q9VZD2.1
#=GS G1SKG1_RABIT/549-658    AC G1SKG1.1
#=GS Q6ZIU7_ORYSJ/198-307    AC Q6ZIU7.1
#=GS F4NS58_BATDJ/150-241    AC F4NS58.1
#=GS F6V4T7_CALJA/561-670    AC F6V4T7.1
#=GS B4MNV6_DROWI/1169-1278  AC B4MNV6.1
#=GS H3FK28_PRIPA/335-443    AC H3FK28.1
#=GS F1SHA8_PIG/157-219      AC F1SHA8.1
#=GS H3AWL5_LATCH/326-435    AC H3AWL5.1
#=GS F8PJ91_SERL3/170-275    AC F8PJ91.1
#=GS F6S1N7_ORNAN/146-240    AC F6S1N7.1
#=GS H3J340_STRPU/8-70       AC H3J340.1
#=GS H9HHR5_ATTCE/1-80       AC H9HHR5.1
#=GS B4KUH9_DROMO/1195-1304  AC B4KUH9.1
#=GS D6X2P6_TRICA/410-519    AC D6X2P6.1
#=GS A8XZ57_CAEBR/254-362    AC A8XZ57.2
#=GS A1A5S8_DANRE/303-411    AC A1A5S8.1
#=GS F7EXI8_MACMU/105-214    AC F7EXI8.1
#=GS G3QBV8_GASAC/275-383    AC G3QBV8.1
#=GS I1GBD9_AMPQE/284-393    AC I1GBD9.1
#=GS F6XUP9_HORSE/215-324    AC F6XUP9.1
#=GS H9JB93_BOMMO/536-645    AC H9JB93.1
#=GS H9F7E0_MACMU/416-525    AC H9F7E0.1
#=GS E9J9C9_SOLIN/143-208    AC E9J9C9.1
#=GS B4J485_DROGR/1252-1361  AC B4J485.1
#=GS I0Z9N8_9CHLO/190-299    AC I0Z9N8.1
#=GS BIN3D_SCHPO/146-256     AC Q9Y7L2.1
#=GS E3S4S4_PYRTT/158-261    AC E3S4S4.1
#=GS C6F7A4_PSEMZ/82-106     AC C6F7A4.1
#=GS F6W792_MACMU/157-246    AC F6W792.1
#=GS BIN3D_CAEEL/256-364     AC Q9U2R0.1
#=GS D6WKB7_TRICA/179-285    AC D6WKB7.1
#=GS D8UA82_VOLCA/685-794    AC D8UA82.1
#=GS Q29QM9_DROME/65-170     AC Q29QM9.1
#=GS B4PUX3_DROYA/189-298    AC B4PUX3.1
#=GS Q4RA28_TETNG/1-54       AC Q4RA28.1
#=GS MEPCE_HUMAN/574-683     AC Q7L2J0.1
#=GS MEPCE_HUMAN/574-683     DR PDB; 3G07 B; 574-683;
#=GS MEPCE_HUMAN/574-683     DR PDB; 3G07 A; 574-683;
#=GS MEPCE_HUMAN/574-683     DR PDB; 3G07 D; 574-683;
#=GS MEPCE_HUMAN/574-683     DR PDB; 3G07 F; 574-683;
#=GS MEPCE_HUMAN/574-683     DR PDB; 3G07 C; 574-683;
#=GS MEPCE_HUMAN/574-683     DR PDB; 3G07 E; 574-683;
#=GS B4G488_DROPE/1-53       AC B4G488.1
#=GS G6CXR9_DANPL/528-637    AC G6CXR9.1
#=GS F1QCI6_DANRE/139-246    AC F1QCI6.1
#=GS A0BHC8_PARTE/241-354    AC A0BHC8.1
#=GS D7FLW6_ECTSI/352-463    AC D7FLW6.1
#=GS D1GXY0_DROAN/196-305    AC D1GXY0.1
#=GS D2HJC2_AILME/141-234    AC D2HJC2.1
#=GS Q4SFJ1_TETNG/544-602    AC Q4SFJ1.1
#=GS G3T987_LOXAF/556-665    AC G3T987.1
#=GS B7FP03_PHATC/420-534    AC B7FP03.1
#=GS A9V8B1_MONBE/239-337    AC A9V8B1.1
#=GS G0T1D4_RHOG2/277-386    AC G0T1D4.1
#=GS D1GXY1_DROAN/196-305    AC D1GXY1.1
#=GS G3WAE3_SARHA/482-591    AC G3WAE3.1
#=GS B4LIM1_DROVI/1190-1299  AC B4LIM1.1
#=GS E2QYY5_CANFA/156-251    AC E2QYY5.1
#=GS C6T1B4_SOYBN/167-241    AC C6T1B4.1
#=GS G3IFS7_CRIGR/155-257    AC G3IFS7.1
#=GS C3Z096_BRAFL/137-219    AC C3Z096.1
#=GS H2Z7P3_CIOSA/48-157     AC H2Z7P3.1
#=GS H2NH86_PONAB/157-252    AC H2NH86.1
#=GS Q7RLF1_PLAYO/278-395    AC Q7RLF1.1
#=GS D1GYZ4_DROAP/193-302    AC D1GYZ4.1
#=GS F8NHQ0_SERL9/170-275    AC F8NHQ0.1
#=GS C5XN48_SORBI/192-301    AC C5XN48.1
#=GS B4IZP4_DROGR/138-243    AC B4IZP4.1
#=GS Q8IHR1_PLAF7/264-383    AC Q8IHR1.1
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B3NC30_DROER/133-238               ............KFDAICCYSITMWIHLNHHDQGLRFFLHKLSNLA--...........-..ELLVVEPQPWKCYQ...KA....E....R........R...L............K.......K...A....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------geifplflelkwrsdvdlqiqkyleealdrrkifesaptkwqrkicfyr.........
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#=GR MEPCE_HUMAN/574-683     SS    ............-EEEEEEES-HHHHHHHHHHHHHHHHHHHHHHHEEE...........E..EEEEEE---HHHHH...TT....T....T........S...-............H.......H...H....H....HH....HHH--......-...-GG...G..H.H....HHHTSTT..T.---...EEE.........EEXX.XX..X......XXXX.....X.X--EEEEE-..........................................................
B4G488_DROPE/1-53                  ............------------------------------------...........-..--------------...--....-....-........-...-............E.......N...I....R....EN....YNSIK......F...RPD...Q..F.P....EYLLSPE..V.GFA...SME.........LMGI.PE..H......CKTG.....F.KRPIQIFKK..........................................................
G6CXR9_DANPL/528-637               ............QFDLILCLSTTKWLHLNWGDAGLKRAFRRMFADLRP...........G..GKLVLEAQNWASYK...KK....K....R........L...T............P.......T...I....Y....EN....FNSIE......L...FPN...K..F.R....EYLLSPE..V.GFS...KCC.........ILGV.PQ..H......ASKG.....F.RRPIQLYVK..........................................................
F1QCI6_DANRE/139-246               ...........r-FHLSTCFAVTMWVHLNHGDAAFLSLLSRLASH---...........S..EYLLLEAQPWKCYR...SA....A....R........R...L............R.......K...L....GrsdfDH....FKALK......I...RGD...M..A.A....HA-----..-.---...---.........----.--..-......----.....-.---------rehlekqcsmelvqcfgntswdrslllfrr............................
A0BHC8_PARTE/241-354               ............KYDTVLCLSVTKWIHLNFGDVGIKRLFKTISNSLNE...........G..GHFILEPQEWKSYK...KK....K....Y........Y...S............T.......E...F....K....QN....YKEIQ......L...KPQ...D..F.S....KVLEK-E..Y.NFK...LIQqi....npdDESA.IK..K......SKST.....F.RRPILIFEK..........................................................
D7FLW6_ECTSI/352-463               ...........g-YDVVCLFSVVKWMHINGGDEALRGVFRKTYSLLRP...........G..GRLILEPQPWKTYR...KS....A....R........Q...H............Gl.....pE...A....A....VI....VGTIK......L...RPQ...D..F.P....AYLTG-E..V.GFR...SWE.........EVGL.PA..E......GVGG.....FaKRSVHVFVK..........................................................
D1GXY0_DROAN/196-305               ............QFDVILCLSVTKWIHLNFGDAGLKQAFRRMFLQLRP...........G..GKLVLEPQAFDGYK...RR....K....K........L...S............E.......Q...I....R....EN....YNNIK......F...RPE...H..F.T....EYLLGPE..V.GFA...SMD.........LMGI.PE..H......CEAG.....F.KRPIEIFTK..........................................................
D2HJC2_AILME/141-234               ...........v-FDIGFCMSITMWIHLNHGDHGLREFLAHLSSLCR-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhdfdhfhslairgdmakqivqiltqdhgmelvccf.....................
Q4SFJ1_TETNG/544-602               ......istlll------------------------------------...........-..--------------...--....-....-........-...Q............D.......I...I....S....KN....FHSIR......L...KPD...Q..F.S....SYLTT-E..V.GFT...SFE.........YLGA.PK..C......PNKG.....F.QRPIFLFHK..........................................................
G3T987_LOXAF/556-665               ............EYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRP...........G..GILVLEPQPWSSYG...KR....K....T........L...T............E.......T...I....Y....KN....YYRIQ......L...KPE...Q..F.S....SYLTSPE..V.GFS...SYE.........LVAT.PH..N......TSKG.....F.QRPVYLFHK..........................................................
B7FP03_PHATC/420-534               ..........qt--DITSIFSTTMWIHMHGGDEGLKRVLKRVCATS--...........K..HFILIESQPSRCYR...AA....K....-........-...M............R.......Q...R....R....MN....LTEMD......V...SPQ...R..L.T....MRLNIE-..-.---...---.........----.--..-......----.....-.---------eeienilkidgfdrvkddgmttvdsntswnrklrlyar....................
A9V8B1_MONBE/239-337               ............RFHTILCLDVPKFVHLTHGDEGLRLLFAVQVELLLP...........G..GILVVQYQGWPSYT...RD....R....N........R...T............A.......L...Y....N....YF....MGRIT......L...QPA...A..F.A....GWLNEC-..H.GLE...LVD.........EHV-.--..-......----.....-.---------viqgratp..................................................
G0T1D4_RHOG2/277-386               ..........dd---VRYSFSVTKWIHLSGLNPALLTFFRRCFDCLRP...........G..GKLILEPQPFSTYA...RN....V....K........M...T............P.......E...L....Q....EN....YDRLKegaekgW...RAEe.gD..F.E....RVLLEL-..V.GFE...KRE.........LLGE.--..-......----.....-.---------tgkigrrrfis...............................................
D1GXY1_DROAN/196-305               ............QFDVILCLSVTKWIHLNFGDAGLKQAFRRMFLQLRP...........G..GKLVLEPQAFDGYK...RR....K....K........L...S............E.......Q...I....R....EN....YNNIK......F...RPE...H..F.T....EYLLGPE..V.GFA...SMD.........LMGI.PE..H......CEAG.....F.KRPIEIFTK..........................................................
G3WAE3_SARHA/482-591               ............EYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRP...........G..GILVLEPQPWSSYG...KR....K....T........L...T............E.......T...I....Y....KN....YYRIQ......L...KPE...Q..F.S....SYLTSPE..V.GFS...SYE.........LVAT.PH..N......SSKG.....F.QRPVYLFHK..........................................................
B4LIM1_DROVI/1190-1299             ............QYDLILCLSVTKWMHLNFGDAGLKLAFKRIFNQLRP...........G..GKLILEAQNWASYK...KK....K....N........L...T............P.......E...I....Y....NN....YKQIE......F...FPN...K..F.H....EYLLSSE..V.GFS...HSY.........TLGV.PR..H......MNKG.....F.CRPIQLYAK..........................................................
E2QYY5_CANFA/156-251               ...........v-FDIGFCMSVTMWIHLNHGDHGLWEFLAHLSSLCR-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhdfdhfrslairgdmanqivqiltqdhgmelvccfgn...................
C6T1B4_SOYBN/167-241               ............QYDTILCLSVSKWIHLNWGDDGLITLFAEVWKLLRP...........G..GIFVLEPQPWKSYE...SN....R....N........V...S............E.......T...T....A....AN....YRNIM......I...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------drtvse....................................................
G3IFS7_CRIGR/155-257               ...........v-FDIVFCMSVTMWIHLNHGDHGLWEFLAHLSSVCQ-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhsfdhfssltirgdmtsqivriltqdhamelvrcfgntswdrsl............
C3Z096_BRAFL/137-219               ............KFDVTFCFSVTMWIHLQNGDSGLMDFLRSVSSWTR-...........-..-FLLLEPQPWKCYR...SA....G....R........R...L............R.......K...-....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------lgrdefprlktlrirgdvereidrclt...............................
H2Z7P3_CIOSA/48-157                ............EYDVIMCMSVTKWMHMNWGDAGIKKTFERFFKQLRA...........G..GKLILEPQDWKSYG...KK....K....K........L...T............E.......R...I....Y....NH....YHSIE......L...LPS...M..F.P....DYLINV-..V.GFE...SVE........yLTST.VP..N......TPVG.....F.KRPIQLYRK..........................................................
H2NH86_PONAB/157-252               ...........v-FDIGFCMSITMWIHLNHGDHGLWEFLAHLSSLCR-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhdfdhfhsltirgdmpnqivqiltqdhgmeliccfgn...................
Q7RLF1_PLAYO/278-395               ............KYDVIICFSVLKWIHLNYGDNKLILFFDLVYKLLKS...........G..GYFILEYHREIKYK...LK....K....N........E...R............I.......F...F....L....KK....KKALK......M...NYT...H..F.D....NIAQGGYnnIaKFI...LIN.........KTDF.KS..D......SKRKrdtgmF.NRTICIYKK..........................................................
D1GYZ4_DROAP/193-302               ............QFDVILCLSVTKWIHLNFGDAGLKQAFRRMFLQLRP...........G..GKLVLEPQAFDGYK...RR....K....K........L...S............E.......Q...I....R....EN....YNNIK......F...RPE...H..F.T....EYLLGPE..V.GFA...SMD.........LMGI.PE..H......CEAG.....F.KRPIEIFTK..........................................................
F8NHQ0_SERL9/170-275               ...........p-YDVVLAFSISKWIHLNSGDAGITKFFNRVHNVLKP...........G..GAFVLEPQDWDTYA...KA....K....R........M...D............E.......T...L....K....EN....AKSLK......L...LPE...D..F.E....TILQS--..I.GFG...PVQ.........HLGS.AG..-......-EGG.....F.HRPVDLYIK..........................................................
C5XN48_SORBI/192-301               ............QYETILCLSVTKWIHLNWGDDGLVTLFVKIWRLLRP...........G..GVFIMEPQPWSSYK...NN....R....L........V...S............E.......L...A....K....EN....FNTIC......I...YPE...T..F.R....EILLD-K..I.GFR...SVE........lIADR.LV..G......TVSG.....F.NRPIEVYHK..........................................................
B4IZP4_DROGR/138-243               ............KFDAICCYSITMWIHLNHHDSGLQLFLRKLSQL---...........S..ELFVVEPQPWKCYQ...TA....Er.rlK........K...A............G.......E...V....F....PM....FVELK......W...RSDveqQ..I.Q....RYLQQ-E..L.GRN...C--.........----.--..-......----.....-.---------vyestptkwqrkicfyr.........................................
Q8IHR1_PLAF7/264-383               ...........t-YDIILAFSVIKWIHLNNGDEHLILFFDRVYFMLRK...........N..GYFILEYNKEKKYK...LR....K....I........Q...Kky........ykK.......N...I....S....LN....YTHFD.....dIaqgKYN...N..N.S...rMVLVN-K..F.FFF...TNKg.......dERSK.NK..N......KLGM.....F.NREICIYQK..........................................................
Q55FU0_DICDI/325-433               ...........s-YDVITALSISKWIQLNWGDEGIKKFLIKIYSLLKD...........G..GIFLFEPQPWKGYS...KR....K....N........L...T............E.......L...I....N....KN....YKEIK......F...KPD...Q..F.T....NFLIET-..V.GYK...SFE.........FLNS.NE..A......KSKG.....F.DRPLYKFIK..........................................................
G1PEN0_MYOLU/157-248               ...........v-FDIGFCMSITMWIHLNHGDHGLWEFLAHLSSLCH-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhdfdhfhslairgdmasqivqiltqdhgmelvc.......................
E4WVS7_OIKDI/246-353               ............EYDTIIAFSVSKWVHLNNGDNGIKRFFRRIFRQLRP...........G..GRFLLEPQPWKSYA...RR....K....K........L...T............P.......E...I....E....EN....YKNIK......F...KPA...E..F.T....SFLTS--..I.GFS...DPI.........NLTS.A-..Q......SEKG.....FkQREVLLYNK..........................................................
D8T5W1_SELML/165-274               ...........t-YDTILCLSISKWIHLNWGDEGLLKFFAKVFKELRP...........G..GRLVLEPQPWESYS...KK....R....R........V...S............E.......V...T....R....KN....FQRIK......L...RPD...N..F.P....SILTE-K..I.GFK...FYE.........EISSeLP..S......DKSG.....F.RRPLFVYHK..........................................................
E1FLX1_LOALO/1-40                  ...........m------------------------------------...........-..--------------...--....-....-........-...-............-.......-...-....-....--....-----......-...-PN...A..F.Q....EYLVV-D..I.GFD...FCQ.........HIDP.PK..A......HAKG.....F.ERPIQVYCK..........................................................
G7N6X7_MACMU/157-246               ...........v-FDIGFCMSITMWIHLNHGDHGLWEFLAHLSSLCH-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhdfdhfhslairgdmtnqivqiltqdhgmel.........................
A1L521_BOVIN/105-214               ............EYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRP...........G..GILVLEPQPWSSYG...RR....K....T........L...T............E.......R...I....Y....KN....YFRIQ......L...KPE...Q..F.S....SYLTSPE..V.GFS...SYE.........LVAT.PN..N......TSRG.....F.QRPVYLFHK..........................................................
BN3D2_BOVIN/157-255                ...........v-FDIGFCMSVTMWIHLNHGDQGLWEFLAHLSSLCR-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------glhdfdhfrslairgdmasqivqiltqdhgmelvccfgntkw................
G3WBR1_SARHA/159-249               ...........v-FDIVFCMSITMWIHLNHGDNGLLAFLAHLASLCR-...........-..-YLLVEPQPWKCYR...AA....A....R........R...L............R.......K...L....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------grhnfdhfrslalhgdmadriiqiltkdhgmelv........................
B3P2J0_DROER/188-297               ............QFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQLRP...........G..GKLILEPQSFDGYK...RR....K....K........L...S............E.......Q...I....R....NN....YNAIK......F...RPE...H..F.T....EYLLSPE..V.GFA...EME.........LMGV.PE..H......CEVG.....F.KRPIQIFT-r.........................................................
D6W5V7_HUMAN/105-214               ............EYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRP...........G..GILVLEPQPWSSYG...KR....K....T........L...T............E.......T...I....Y....KN....YYRIQ......L...KPE...Q..F.S....SYLTSPD..V.GFS...SYE.........LVAT.PH..N......TSKG.....F.QRPVYLFHK..........................................................
C6F797_PSEMZ/70-94                 ...........t-YDTVLCLSVTKWVHLNWGDEWLIR-----------...........-..--------------...--....-....-........-...-............-.......-...-....-....--....-----......-...---...-..-.-....-------..-.---...---.........----.--..-......----.....-.---------..........................................................
#=GC SS_cons                       ............-EEEEEEES-HHHHHHHHHHHHHHHHHHHHHHHEEE...........E..EEEEEE---HHHHH...TT....T....T........S...-............H.......H...H....H....HH....HHH--......-...-GG...G..H.H....HHHTSTT..T.---...EEE.........EEXX.XX..X......XXXX.....X.X--EEEEE-..........................................................
#=GC seq_cons                      ............paDllLCLSlTKWlHLNaGDpGLpphFp+laphL+s...........G..GhLllEPQsWpsYp...+t....c....p........h...s............c.......p...h....h....pp....a.plp......h...hPp...p..F.t....phLht....l.GFt................ht................s.....h.pR.l.hh............................................................
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