#=GF ID Bin3
#=GF AC PF06859.7
#=GF DE Bicoid-interacting protein 3 (Bin3)
#=GF AU Vella Briffa B
#=GF SE Pfam-B_5564 (release 10.0)
#=GF GA 21.00 21.00;
#=GF TC 21.20 21.10;
#=GF NC 20.90 20.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 10717484
#=GF RT Identification of drosophila bicoid-interacting proteins using a
#=GF RT custom two-hybrid selection.
#=GF RA Zhu W, Hanes SD;
#=GF RL Gene 2000;245:329-339.
#=GF DR INTERPRO; IPR010675;
#=GF CC This family represents a conserved region of approximately 120
#=GF CC residues within eukaryotic Bicoid-interacting protein 3 (Bin3).
#=GF CC Bin3, which shows similarity to a number of protein
#=GF CC methyltransferases that modify RNA-binding proteins, interacts
#=GF CC with Bicoid, which itself directs pattern formation in the early
#=GF CC Drosophila embryo. The interaction might allow Bicoid to switch
#=GF CC between its dual roles in transcription and translation [1].
#=GF CC Note that family members contain a conserved HLN motif.
#=GF SQ 294
#=GS F7EXI4_MACMU/574-683 AC F7EXI4.1
#=GS B4LZ69_DROVI/222-331 AC B4LZ69.1
#=GS H9L3R8_CHICK/161-243 AC H9L3R8.1
#=GS E6ZF28_DICLA/143-250 AC E6ZF28.1
#=GS B3L5R2_PLAKH/300-419 AC B3L5R2.1
#=GS C6F7A5_PSEMZ/82-106 AC C6F7A5.1
#=GS Q6NPC9_ARATH/209-318 AC Q6NPC9.1
#=GS H2WN39_CAEJA/238-346 AC H2WN39.1
#=GS C6F7B0_PSEMZ/82-106 AC C6F7B0.1
#=GS B6JVZ4_SCHJY/205-263 AC B6JVZ4.1
#=GS B3KP86_HUMAN/105-214 AC B3KP86.1
#=GS Q7T0L7_XENLA/143-242 AC Q7T0L7.1
#=GS H0XA29_OTOGA/158-251 AC H0XA29.1
#=GS G7L862_MEDTR/184-293 AC G7L862.1
#=GS B4JUG9_DROGR/210-319 AC B4JUG9.1
#=GS G4TL58_PIRID/213-315 AC G4TL58.1
#=GS F1KVT1_ASCSU/419-527 AC F1KVT1.1
#=GS B0W1L8_CULQU/659-768 AC B0W1L8.1
#=GS C6F798_PSEMZ/82-106 AC C6F798.1
#=GS C5KGT0_PERM5/244-356 AC C5KGT0.1
#=GS H2PLN2_PONAB/105-214 AC H2PLN2.1
#=GS H0XUS6_OTOGA/143-237 AC H0XUS6.1
#=GS G7MNU3_MACMU/443-551 AC G7MNU3.1
#=GS Q5R619_PONAB/105-214 AC Q5R619.1
#=GS G9KAB5_MUSPF/557-666 AC G9KAB5.1
#=GS D7TBJ3_VITVI/177-286 AC D7TBJ3.1
#=GS G8F4G3_MACFA/427-535 AC G8F4G3.1
#=GS E2QC61_DROME/1003-1112 AC E2QC61.1
#=GS H3GI20_PHYRM/237-345 AC H3GI20.1
#=GS H9KPT2_APIME/134-243 AC H9KPT2.1
#=GS Q29ED3_DROPS/130-235 AC Q29ED3.1
#=GS C6F796_PSEMZ/82-106 AC C6F796.1
#=GS G3I651_CRIGR/358-467 AC G3I651.1
#=GS H0XH66_OTOGA/561-670 AC H0XH66.1
#=GS A8JDX0_CHLRE/163-273 AC A8JDX0.1
#=GS F6TDY8_MONDO/159-259 AC F6TDY8.1
#=GS E2BW52_HARSA/922-1031 AC E2BW52.1
#=GS A8E7D2_DANRE/127-234 AC A8E7D2.1
#=GS F4WT37_ACREC/499-607 AC F4WT37.1
#=GS Q4RIJ9_TETNG/133-239 AC Q4RIJ9.1
#=GS H2QV26_PANTR/574-683 AC H2QV26.1
#=GS B4H1V6_DROPE/130-235 AC B4H1V6.1
#=GS D7MQX7_ARALL/204-313 AC D7MQX7.1
#=GS E3LRN2_CAERE/267-375 AC E3LRN2.1
#=GS A9SNK5_PHYPA/235-344 AC A9SNK5.1
#=GS D5GLM2_TUBMM/143-250 AC D5GLM2.1
#=GS D3BBS5_POLPA/347-456 AC D3BBS5.1
#=GS B4PHU8_DROYA/133-238 AC B4PHU8.1
#=GS D8SHL2_SELML/165-274 AC D8SHL2.1
#=GS Q5I0E0_RAT/214-323 AC Q5I0E0.1
#=GS A5K5B5_PLAVS/318-411 AC A5K5B5.1
#=GS C6F7A6_PSEMZ/82-106 AC C6F7A6.1
#=GS B4KWS9_DROMO/136-241 AC B4KWS9.1
#=GS BN3D2_MOUSE/158-245 AC Q91YP1.1
#=GS F7H083_CALJA/157-246 AC F7H083.1
#=GS B4QD82_DROSI/1004-1113 AC B4QD82.1
#=GS C1E1J2_MICSR/268-380 AC C1E1J2.1
#=GS E2A668_CAMFO/457-566 AC E2A668.1
#=GS E2A3K2_CAMFO/134-241 AC E2A3K2.1
#=GS Q016F6_OSTTA/181-298 AC Q016F6.1
#=GS H2PLN1_PONAB/573-682 AC H2PLN1.1
#=GS B0WI06_CULQU/687-796 AC B0WI06.1
#=GS C6F7A1_PSEMZ/82-106 AC C6F7A1.1
#=GS G4YH69_PHYSP/257-363 AC G4YH69.1
#=GS C6F7B3_9CONI/82-106 AC C6F7B3.1
#=GS H0Z120_TAEGU/82-183 AC H0Z120.1
#=GS G1DG08_CAPHI/105-214 AC G1DG08.1
#=GS A8QAZ0_MALGO/176-259 AC A8QAZ0.1
#=GS A8K5Q1_HUMAN/574-683 AC A8K5Q1.1
#=GS C6F7A3_PSEMZ/82-106 AC C6F7A3.1
#=GS B3LZX5_DROAN/130-235 AC B3LZX5.1
#=GS B4HU55_DROSE/133-238 AC B4HU55.1
#=GS I1CMA2_RHIO9/154-262 AC I1CMA2.1
#=GS G3NQ71_GASAC/128-234 AC G3NQ71.1
#=GS H2RW25_TAKRU/445-555 AC H2RW25.1
#=GS Q9LU61_ARATH/270-379 AC Q9LU61.1
#=GS D2V086_NAEGR/322-445 AC D2V086.1
#=GS E3X8N0_ANODA/787-897 AC E3X8N0.1
#=GS C6F7A9_PSEMZ/82-106 AC C6F7A9.1
#=GS A7SJ10_NEMVE/155-264 AC A7SJ10.1
#=GS B4H643_DROPE/1095-1204 AC B4H643.1
#=GS A2YXL5_ORYSI/198-318 AC A2YXL5.1
#=GS I1QLD6_ORYGL/194-303 AC I1QLD6.1
#=GS B0D6P1_LACBS/146-238 AC B0D6P1.1
#=GS B4II51_DROSE/1001-1110 AC B4II51.1
#=GS D4ABH7_RAT/158-246 AC D4ABH7.1
#=GS B3NC30_DROER/133-238 AC B3NC30.1
#=GS I1KPY6_SOYBN/167-276 AC I1KPY6.1
#=GS E2RGJ1_CANFA/566-675 AC E2RGJ1.1
#=GS E5A0R6_LEPMJ/359-462 AC E5A0R6.1
#=GS B6HG65_PENCW/127-220 AC B6HG65.1
#=GS H9HZB6_ATTCE/60-124 AC H9HZB6.1
#=GS BN3D2_PONAB/157-252 AC Q5RFI3.1
#=GS B4I463_DROSE/285-394 AC B4I463.1
#=GS Q7PZU2_ANOGA/651-760 AC Q7PZU2.4
#=GS Q297L6_DROPS/194-303 AC Q297L6.2
#=GS B3LWF0_DROAN/196-305 AC B3LWF0.1
#=GS D0MZS5_PHYIT/254-360 AC D0MZS5.1
#=GS B4LGW8_DROVI/134-239 AC B4LGW8.1
#=GS E9JD11_SOLIN/456-564 AC E9JD11.1
#=GS B2WHX3_PYRTR/134-237 AC B2WHX3.1
#=GS C6F7A8_PSEMZ/82-106 AC C6F7A8.1
#=GS G1S803_NOMLE/157-250 AC G1S803.1
#=GS D0NPB1_PHYIT/191-299 AC D0NPB1.1
#=GS Q6XHG4_DROYA/133-176 AC Q6XHG4.1
#=GS H9GHU6_ANOCA/530-639 AC H9GHU6.1
#=GS B7PJP2_IXOSC/456-565 AC B7PJP2.1
#=GS Q5TXE3_ANOGA/179-288 AC Q5TXE3.3
#=GS H2V1G6_TAKRU/429-537 AC H2V1G6.1
#=GS B5DU34_DROPS/1164-1273 AC B5DU34.1
#=GS I1I943_BRADI/207-316 AC I1I943.1
#=GS G1TJW0_RABIT/561-670 AC G1TJW0.1
#=GS B4QQK8_DROSI/133-238 AC B4QQK8.1
#=GS D8QDP5_SCHCM/162-286 AC D8QDP5.1
#=GS H3BF65_LATCH/159-266 AC H3BF65.1
#=GS E2B3M0_HARSA/138-203 AC E2B3M0.1
#=GS BN3D1_DROME/1003-1112 AC Q7K480.1
#=GS Q23GA7_TETTS/467-578 AC Q23GA7.1
#=GS F1QE64_DANRE/414-522 AC F1QE64.1
#=GS C6F799_PSEMZ/82-106 AC C6F799.1
#=GS E9C876_CAPO3/348-458 AC E9C876.1
#=GS B3NB62_DROER/1007-1116 AC B3NB62.1
#=GS E4Y7R0_OIKDI/246-353 AC E4Y7R0.1
#=GS G3TKP3_LOXAF/158-258 AC G3TKP3.1
#=GS H3GJA5_PHYRM/254-359 AC H3GJA5.1
#=GS F2EIF4_HORVD/210-319 AC F2EIF4.1
#=GS E6ZLK6_SPORE/258-364 AC E6ZLK6.1
#=GS G7PI92_MACFA/157-246 AC G7PI92.1
#=GS F2U8A7_SALS5/157-222 AC F2U8A7.1
#=GS B4QXI9_DROSI/196-305 AC B4QXI9.1
#=GS Q0IG46_AEDAE/688-797 AC Q0IG46.1
#=GS F6XIE4_MOUSE/58-167 AC F6XIE4.1
#=GS C0MJ20_DROME/190-299 AC C0MJ20.1
#=GS C1MKI3_MICPC/275-371 AC C1MKI3.1
#=GS H2LR63_ORYLA/142-249 AC H2LR63.1
#=GS C6F7A2_PSEMZ/82-106 AC C6F7A2.1
#=GS F4WP52_ACREC/142-209 AC F4WP52.1
#=GS H2VCX5_TAKRU/135-241 AC H2VCX5.1
#=GS E3XB59_ANODA/1085-1157 AC E3XB59.1
#=GS A4RSG9_OSTLU/108-223 AC A4RSG9.1
#=GS G5AN29_HETGA/482-591 AC G5AN29.1
#=GS Q4SFJ1_TETNG/470-539 AC Q4SFJ1.1
#=GS B3MJ56_DROAN/1032-1141 AC B3MJ56.1
#=GS B4NYT6_DROYA/1005-1114 AC B4NYT6.1
#=GS H9KCM8_APIME/142-249 AC H9KCM8.1
#=GS E0VAV2_PEDHC/632-741 AC E0VAV2.1
#=GS G3QRK4_GORGO/574-683 AC G3QRK4.1
#=GS C6F7A0_PSEMZ/73-97 AC C6F7A0.1
#=GS F1QAZ2_DANRE/112-219 AC F1QAZ2.1
#=GS E2LJJ6_MONPE/31-82 AC E2LJJ6.1
#=GS H9JVI7_BOMMO/131-243 AC H9JVI7.1
#=GS B9PI44_TOXGO/469-566 AC B9PI44.1
#=GS B9ILR2_POPTR/212-321 AC B9ILR2.1
#=GS G0MZ23_CAEBE/264-372 AC G0MZ23.1
#=GS Q4XED7_PLACH/118-136 AC Q4XED7.1
#=GS B0W3M2_CULQU/179-290 AC B0W3M2.1
#=GS H3CXF7_TETNG/401-509 AC H3CXF7.1
#=GS G7YHB8_CLOSI/373-478 AC G7YHB8.1
#=GS G4ZR14_PHYSP/195-303 AC G4ZR14.1
#=GS A8PFD8_BRUMA/395-515 AC A8PFD8.1
#=GS E9HI70_DAPPU/131-239 AC E9HI70.1
#=GS G4VDU5_SCHMA/327-432 AC G4VDU5.1
#=GS Q4PGH9_USTMA/376-482 AC Q4PGH9.1
#=GS Q4R3R7_MACFA/106-215 AC Q4R3R7.1
#=GS G1SFM5_RABIT/158-255 AC G1SFM5.1
#=GS A2RVW3_DROPS/1159-1268 AC A2RVW3.2
#=GS MEPCE_MOUSE/551-660 AC Q8K3A9.2
#=GS H3DQW6_TETNG/1-102 AC H3DQW6.1
#=GS C6F7A7_PSEMZ/82-106 AC C6F7A7.1
#=GS F6WC50_HORSE/157-252 AC F6WC50.1
#=GS F6R6T5_MONDO/562-671 AC F6R6T5.1
#=GS C6F7B1_PSEMZ/82-106 AC C6F7B1.1
#=GS B6KD62_TOXGO/469-566 AC B6KD62.1
#=GS B3RLM9_TRIAD/195-295 AC B3RLM9.1
#=GS G3N867_GASAC/223-326 AC G3N867.1
#=GS G3V656_RAT/545-654 AC G3V656.1
#=GS C0MJ21_DROME/190-299 AC C0MJ21.1
#=GS D1GXX3_DROAN/196-305 AC D1GXX3.1
#=GS H0VMW4_CAVPO/132-229 AC H0VMW4.1
#=GS A8PCE2_COPC7/195-314 AC A8PCE2.2
#=GS D5AAQ7_PICSI/70-179 AC D5AAQ7.1
#=GS G5AU11_HETGA/168-266 AC G5AU11.1
#=GS B4N478_DROWI/133-238 AC B4N478.1
#=GS F0W384_9STRA/273-320 AC F0W384.1
#=GS H3J339_STRPU/481-567 AC H3J339.1
#=GS D2HX16_AILME/515-624 AC D2HX16.1
#=GS A3KQ55_DANRE/587-695 AC A3KQ55.1
#=GS E5S6E5_TRISP/397-506 AC E5S6E5.1
#=GS H0VXF6_CAVPO/471-580 AC H0VXF6.1
#=GS F1R4M0_DANRE/329-437 AC F1R4M0.1
#=GS H2Q5V9_PANTR/157-250 AC H2Q5V9.1
#=GS F1R5Z5_DANRE/514-622 AC F1R5Z5.1
#=GS B4KCB5_DROMO/205-314 AC B4KCB5.1
#=GS C6F7B2_PSEMZ/82-106 AC C6F7B2.1
#=GS B7P3N1_IXOSC/130-237 AC B7P3N1.1
#=GS G7E3Y2_MIXOS/989-1103 AC G7E3Y2.1
#=GS A8WFR5_DANRE/329-437 AC A8WFR5.1
#=GS G4VDU4_SCHMA/202-307 AC G4VDU4.1
#=GS G1PE92_MYOLU/565-674 AC G1PE92.1
#=GS F0VJ74_NEOCL/471-558 AC F0VJ74.1
#=GS F6V4K7_CALJA/105-214 AC F6V4K7.1
#=GS F6VWX5_MONDO/545-654 AC F6VWX5.1
#=GS BN3D2_HUMAN/157-250 AC Q7Z5W3.1
#=GS F4PUL7_DICFS/299-408 AC F4PUL7.1
#=GS G3WAE2_SARHA/1212-1321 AC G3WAE2.1
#=GS F1RMY9_PIG/575-684 AC F1RMY9.1
#=GS E1Z513_CHLVA/425-539 AC E1Z513.1
#=GS A4IG11_DANRE/203-311 AC A4IG11.1
#=GS BN3D2_DROME/190-299 AC Q9VNH1.2
#=GS C5YHA3_SORBI/197-306 AC C5YHA3.1
#=GS G1KHR3_ANOCA/155-239 AC G1KHR3.1
#=GS Q174R7_AEDAE/174-283 AC Q174R7.1
#=GS F7AZ70_CIOIN/48-157 AC F7AZ70.2
#=GS F2UBU0_SALS5/793-899 AC F2UBU0.1
#=GS C3XPI0_BRAFL/77-186 AC C3XPI0.1
#=GS B4NLC1_DROWI/194-303 AC B4NLC1.1
#=GS Q498W0_DANRE/111-219 AC Q498W0.1
#=GS G3QKH1_GORGO/79-179 AC G3QKH1.1
#=GS Q9VZD2_DROME/133-238 AC Q9VZD2.1
#=GS G1SKG1_RABIT/549-658 AC G1SKG1.1
#=GS Q6ZIU7_ORYSJ/198-307 AC Q6ZIU7.1
#=GS F4NS58_BATDJ/150-241 AC F4NS58.1
#=GS F6V4T7_CALJA/561-670 AC F6V4T7.1
#=GS B4MNV6_DROWI/1169-1278 AC B4MNV6.1
#=GS H3FK28_PRIPA/335-443 AC H3FK28.1
#=GS F1SHA8_PIG/157-219 AC F1SHA8.1
#=GS H3AWL5_LATCH/326-435 AC H3AWL5.1
#=GS F8PJ91_SERL3/170-275 AC F8PJ91.1
#=GS F6S1N7_ORNAN/146-240 AC F6S1N7.1
#=GS H3J340_STRPU/8-70 AC H3J340.1
#=GS H9HHR5_ATTCE/1-80 AC H9HHR5.1
#=GS B4KUH9_DROMO/1195-1304 AC B4KUH9.1
#=GS D6X2P6_TRICA/410-519 AC D6X2P6.1
#=GS A8XZ57_CAEBR/254-362 AC A8XZ57.2
#=GS A1A5S8_DANRE/303-411 AC A1A5S8.1
#=GS F7EXI8_MACMU/105-214 AC F7EXI8.1
#=GS G3QBV8_GASAC/275-383 AC G3QBV8.1
#=GS I1GBD9_AMPQE/284-393 AC I1GBD9.1
#=GS F6XUP9_HORSE/215-324 AC F6XUP9.1
#=GS H9JB93_BOMMO/536-645 AC H9JB93.1
#=GS H9F7E0_MACMU/416-525 AC H9F7E0.1
#=GS E9J9C9_SOLIN/143-208 AC E9J9C9.1
#=GS B4J485_DROGR/1252-1361 AC B4J485.1
#=GS I0Z9N8_9CHLO/190-299 AC I0Z9N8.1
#=GS BIN3D_SCHPO/146-256 AC Q9Y7L2.1
#=GS E3S4S4_PYRTT/158-261 AC E3S4S4.1
#=GS C6F7A4_PSEMZ/82-106 AC C6F7A4.1
#=GS F6W792_MACMU/157-246 AC F6W792.1
#=GS BIN3D_CAEEL/256-364 AC Q9U2R0.1
#=GS D6WKB7_TRICA/179-285 AC D6WKB7.1
#=GS D8UA82_VOLCA/685-794 AC D8UA82.1
#=GS Q29QM9_DROME/65-170 AC Q29QM9.1
#=GS B4PUX3_DROYA/189-298 AC B4PUX3.1
#=GS Q4RA28_TETNG/1-54 AC Q4RA28.1
#=GS MEPCE_HUMAN/574-683 AC Q7L2J0.1
#=GS MEPCE_HUMAN/574-683 DR PDB; 3G07 B; 574-683;
#=GS MEPCE_HUMAN/574-683 DR PDB; 3G07 A; 574-683;
#=GS MEPCE_HUMAN/574-683 DR PDB; 3G07 D; 574-683;
#=GS MEPCE_HUMAN/574-683 DR PDB; 3G07 F; 574-683;
#=GS MEPCE_HUMAN/574-683 DR PDB; 3G07 C; 574-683;
#=GS MEPCE_HUMAN/574-683 DR PDB; 3G07 E; 574-683;
#=GS B4G488_DROPE/1-53 AC B4G488.1
#=GS G6CXR9_DANPL/528-637 AC G6CXR9.1
#=GS F1QCI6_DANRE/139-246 AC F1QCI6.1
#=GS A0BHC8_PARTE/241-354 AC A0BHC8.1
#=GS D7FLW6_ECTSI/352-463 AC D7FLW6.1
#=GS D1GXY0_DROAN/196-305 AC D1GXY0.1
#=GS D2HJC2_AILME/141-234 AC D2HJC2.1
#=GS Q4SFJ1_TETNG/544-602 AC Q4SFJ1.1
#=GS G3T987_LOXAF/556-665 AC G3T987.1
#=GS B7FP03_PHATC/420-534 AC B7FP03.1
#=GS A9V8B1_MONBE/239-337 AC A9V8B1.1
#=GS G0T1D4_RHOG2/277-386 AC G0T1D4.1
#=GS D1GXY1_DROAN/196-305 AC D1GXY1.1
#=GS G3WAE3_SARHA/482-591 AC G3WAE3.1
#=GS B4LIM1_DROVI/1190-1299 AC B4LIM1.1
#=GS E2QYY5_CANFA/156-251 AC E2QYY5.1
#=GS C6T1B4_SOYBN/167-241 AC C6T1B4.1
#=GS G3IFS7_CRIGR/155-257 AC G3IFS7.1
#=GS C3Z096_BRAFL/137-219 AC C3Z096.1
#=GS H2Z7P3_CIOSA/48-157 AC H2Z7P3.1
#=GS H2NH86_PONAB/157-252 AC H2NH86.1
#=GS Q7RLF1_PLAYO/278-395 AC Q7RLF1.1
#=GS D1GYZ4_DROAP/193-302 AC D1GYZ4.1
#=GS F8NHQ0_SERL9/170-275 AC F8NHQ0.1
#=GS C5XN48_SORBI/192-301 AC C5XN48.1
#=GS B4IZP4_DROGR/138-243 AC B4IZP4.1
#=GS Q8IHR1_PLAF7/264-383 AC Q8IHR1.1
#=GS Q55FU0_DICDI/325-433 AC Q55FU0.1
#=GS G1PEN0_MYOLU/157-248 AC G1PEN0.1
#=GS E4WVS7_OIKDI/246-353 AC E4WVS7.1
#=GS D8T5W1_SELML/165-274 AC D8T5W1.1
#=GS E1FLX1_LOALO/1-40 AC E1FLX1.1
#=GS G7N6X7_MACMU/157-246 AC G7N6X7.1
#=GS A1L521_BOVIN/105-214 AC A1L521.1
#=GS BN3D2_BOVIN/157-255 AC Q29S19.1
#=GS G3WBR1_SARHA/159-249 AC G3WBR1.1
#=GS B3P2J0_DROER/188-297 AC B3P2J0.1
#=GS D6W5V7_HUMAN/105-214 AC D6W5V7.1
#=GS C6F797_PSEMZ/70-94 AC C6F797.1
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#=GC SS_cons ............-EEEEEEES-HHHHHHHHHHHHHHHHHHHHHHHEEE...........E..EEEEEE---HHHHH...TT....T....T........S...-............H.......H...H....H....HH....HHH--......-...-GG...G..H.H....HHHTSTT..T.---...EEE.........EEXX.XX..X......XXXX.....X.X--EEEEE-..........................................................
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