GenomeNet

Database: Pfam
Entry: Birna_VP2
LinkDB: Birna_VP2
Original site: Birna_VP2 
#=GF ID   Birna_VP2
#=GF AC   PF01766.15
#=GF DE   Birnavirus VP2 protein
#=GF AU   Bateman A
#=GF SE   Pfam-B_946 (release 4.2)
#=GF GA   19.70 19.70;
#=GF TC   691.90 691.50;
#=GF NC   19.00 18.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Birnaviridae
#=GF RN   [1]
#=GF RM   2828658
#=GF RT   Birnavirus precursor polyprotein is processed in Escherichia
#=GF RT   coli by its own virus-encoded polypeptide. 
#=GF RA   Jagadish MN, Staton VJ, Hudson PJ, Azad AA; 
#=GF RL   J Virol 1988;62:1084-1087.
#=GF RN   [2]
#=GF RM   8525637
#=GF RT   Strain variability and localization of important epitopes on the
#=GF RT   major structural protein (VP2) of infectious pancreatic necrosis
#=GF RT   virus. 
#=GF RA   Heppell J, Tarrab E, Lecomte J, Berthiaume L, Arella M; 
#=GF RL   Virology 1995;214:40-49.
#=GF DR   INTERPRO; IPR002662;
#=GF CC   VP2 is the major structural protein of birnaviruses [2]. The
#=GF CC   large RNA segment of birnaviruses codes for a polyprotein
#=GF CC   (N-VP2-VP4-VP3-C) [1].
#=GF SQ   4
#=GS POLS_IBDVU/9-452  AC Q82635.1
#=GS POLS_BSNV/7-428   AC Q8AZM0.1
#=GS POLS_IPNVJ/5-453  AC P05844.2
#=GS POLS_DXV96/2-442  AC Q96724.1
POLS_IBDVU/9-452             QQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQ-SNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMV-ATCDSSDRPRVYTITaaddyqfSSQYQAGGVTITLFSANIDAITSLSI..GGELVFQ...TSVQGLILGATIYLIGFDG....TAVITRA-VAADN--GLTAGTDNLMPFNI---.VIPTSEITQPITSIKLEIVT-SKSGGQAgdqmSWSASGSLAVTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDPGAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRALR
POLS_BSNV/7-428              NTQIRYLNSLLVPETGSTSIPDDTLDRHCLKTETTTENLVAALGGSGLIVLFPNSPSGLLGAHYTKT-PQGSLIFDKAITTSQDLKKAYNYARLVSRIVQVRSSTLPAGVYALNGTFNGVTYIGSLSEIKDLDYNSLLSATANINDKVGNVLVGDGVAVLSLPAGSDLPYVRLGDEVPSSAGV-----ARCSPSDRPRHYNAN.......NKQVQVGTTDTKTNGFNIDATTPTEV..TVDMQIA...QIAAGKTLTVTVKLMGLTG....AKVASRSETVSGN--GGT--------FHFSTTaVFGETEITQPVVGVQVL----AKTNGD-....PIVVDSYVGVTVHGGNMPGTLRPVTIIAYESVATGSVLTLSGISNYELIPNPELAKNIQTSYGKLNPAEMTYTKVVLSHRDELGLRSIWSIPQYRDMMSYFREVSDRSSPLKIAGAFGWGDLLSGIR
POLS_IPNVJ/5-453             KATATYLRSIMLPENGPASIPDDITERHILKQETSSYNLEVSESGSGLLVCFPGAPGSRVGAHYRWNLNQTALEFDQWLETSQDLKKAFNYGRLISRKYDIQSSTLPAGLYALNGTLNAATFEGSLSEVESLTYNSLMSLTTNPQDKVNNQLVTKGITVLNLPTGFDKPYVRLEDETPQGPQSMNGARMRCTAAIAPRRYEIDlp..serLPTVAATGTPTTIYEGNADIVNSTAV..TGDITFQleaEPVNETRFDFILQFLGLDNdvpvVTVTSSTLVTADNYRGASA----------KFTqSIPTEMITKPITRVKLAYQLNQQTAIANaatlGAKGPASVSFSSGNGNVPGVLRPITLVAYEKMTPQSILTVAGVSNYELIPNPDLLKNMVTKYGKYDPEGLNYAKMILSHREELDIRTVWRTEEYKERTRAFKEITDFTSDLPTSKAWGWRDLVRGIR
POLS_DXV96/2-442             NTTNEYLKTLLNPAQFISDIPDDIMIRHVNSAQTITYNLKSGASGTGLIVVYPNTPSSISGFHYIWDSATSNWVFDQYIYTAQELKDSYDYGRLISGSLSIKSSTLPAGVYALNGTFNAVWFQGTLSEVSDYSYDRILSITSNPLDKVGNVLVGDGIEVLSLPQGFNNPYVRLGDKSPSTLSSPTHITNTSQNLATGGAYMIP.......VTTVPGQGFHNKEFSINVDSVGPVDIlwSGQMTMQ...---DEWTVTANYQPLNISG....TLIANSQRTLTWSNTGVSNGSHYMNMNNLNVS.LFHENPPPEPVAAIKININYGNNTNGDS....SFSVDSSFTINVIGGATIGVNSPTVGVGYQGVAEGTAITISGINNYELVPNPDLQKNLPMTYGTCDPHDLTYIKYILSNREQLGLRSVMTLADYNRMKMYMHVLTNYHVDEREASSFDFWQLLKQIK
#=GC seq_cons                pspspYL+SLLhPpsGsuSIPDDhh-RHsL+sEToTYNLpsutoGSGLIVhFPssPuSllGAHYphs.spushhFDQhlhTuQ-LKcuYNYuRLlSRplsl+SSTLPAGVYALNGThNAVTFpGSLSElpDloYNuLhShTuN.pDKVGNVLVG-GlsVLSLPsGaDhPYVRLGDcsPussts.phh.spCssuspPRtYpIs.......sspVtusGsssphauhNlDulssssl..oG-hshQ...p.ssthplssslphlGlsG....stVsops.ssusN..Gsos........phpho.lhsps.ITpPlsulKlth.h.spTsGss....uhsssuSluloltGGNhPGsLRPlTlVAYEpVAsGSllTluGlSNYELIPNP-LtKNlsTpYG+hDPtshsYsKhILScR-cLGlRoVWsht-Yp-hppYF+EloDhsSsL+hAuAFGatDLl+uIR
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