GenomeNet

Database: Pfam
Entry: CAF-1_p150
LinkDB: CAF-1_p150
Original site: CAF-1_p150 
#=GF ID   CAF-1_p150
#=GF AC   PF11600.6
#=GF DE   Chromatin assembly factor 1 complex p150 subunit, N-terminal
#=GF AU   Pollington J
#=GF SE   pdb_1s4z
#=GF GA   23.00 23.00;
#=GF TC   23.00 23.00;
#=GF NC   22.90 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   14765118
#=GF RT   Structural basis of HP1/PXVXL motif peptide interactions and HP1
#=GF RT   localisation to heterochromatin. 
#=GF RA   Thiru A, Nietlispach D, Mott HR, Okuwaki M, Lyon D, Nielsen PR,
#=GF RA   Hirshberg M, Verreault A, Murzina NV, Laue ED; 
#=GF RL   EMBO J. 2004;23:489-499.
#=GF RN   [2]
#=GF RM   12697822
#=GF RT   The methyl-CpG binding protein MBD1 interacts with the p150
#=GF RT   subunit of chromatin  assembly factor 1.
#=GF RA   Reese BE, Bachman KE, Baylin SB, Rountree MR;
#=GF RL   Mol Cell Biol. 2003;23:3226-3236.
#=GF CC   CAF-1_p150 is a polypeptide subunit of CAF-1, which functions in
#=GF CC   depositing newly synthesised and acetylated histones H3/H4 into
#=GF CC   chromatin during DNA replication and repair [1]. CAF-1_p150
#=GF CC   includes the HP1 interaction site, the PEST, KER and ED
#=GF CC   interacting sites. CAF-1_p150 interacts directly with newly
#=GF CC   synthesised and acetylated histones through the acidic KER and
#=GF CC   ED domains. The PEST domain is associated with proteins that
#=GF CC   undergo rapid proteolysis [2].
#=GF SQ   93
#=GS I3MNS2_ICTTR/301-455      AC I3MNS2.1
#=GS G1L5F6_AILME/308-467      AC G1L5F6.1
#=GS H3D6M0_TETNG/258-388      AC H3D6M0.1
#=GS I3J2Y4_ORENI/239-403      AC I3J2Y4.1
#=GS A7F4P3_SCLS1/785-946      AC A7F4P3.1
#=GS M3WK65_FELCA/323-468      AC M3WK65.1
#=GS F1S7L7_PIG/321-480        AC F1S7L7.1
#=GS G3HCF9_CRIGR/291-444      AC G3HCF9.1
#=GS M3XIX8_LATCH/306-469      AC M3XIX8.1
#=GS G1PI42_MYOLU/1-141        AC G1PI42.1
#=GS A0A091DEY6_FUKDA/295-447  AC A0A091DEY6.1
#=GS G3SLF5_LOXAF/345-436      AC G3SLF5.1
#=GS K7EPA1_HUMAN/93-245       AC K7EPA1.7
#=GS V8NFM8_OPHHA/259-422      AC V8NFM8.1
#=GS M4ABP2_XIPMA/235-394      AC M4ABP2.1
#=GS C4JLZ9_UNCRE/115-285      AC C4JLZ9.1
#=GS F6VDM1_CALJA/322-420      AC F6VDM1.1
#=GS H2QF16_PANTR/320-479      AC H2QF16.1
#=GS Q6FN62_CANGA/71-221       AC Q6FN62.1
#=GS C3YNV2_BRAFL/369-543      AC C3YNV2.1
#=GS F6YQD7_XENTR/348-417      AC F6YQD7.1
#=GS CAF1A_DANRE/242-396       AC A0JMK9.1
#=GS U3JEF0_FICAL/283-446      AC U3JEF0.1
#=GS H2ZYI8_LATCH/323-486      AC H2ZYI8.1
#=GS U7PT59_SPOS1/274-383      AC U7PT59.1
#=GS CAF1A_BOVIN/322-481       AC A6QLA6.1
#=GS CAF1A_CHICK/293-456       AC Q5R1T0.1
#=GS M7AWT3_CHEMY/273-433      AC M7AWT3.1
#=GS G7PYM2_MACFA/284-435      AC G7PYM2.1
#=GS U3IL50_ANAPL/273-437      AC U3IL50.1
#=GS G3PN46_GASAC/1-96         AC G3PN46.1
#=GS E9IDN8_SOLIN/240-437      AC E9IDN8.1
#=GS G1QSB4_NOMLE/320-479      AC G1QSB4.1
#=GS Z4YIN8_DANRE/177-331      AC Z4YIN8.1
#=GS S6ESZ0_ZYGB2/44-203       AC S6ESZ0.1
#=GS J5RIC1_SACK1/96-259       AC J5RIC1.1
#=GS F6VDV6_CALJA/367-455      AC F6VDV6.1
#=GS W4YJY9_STRPU/299-469      AC W4YJY9.1
#=GS E7FAY6_DANRE/243-328      AC E7FAY6.1
#=GS B2GSW9_DANRE/242-396      AC B2GSW9.1
#=GS H9G514_ANOCA/261-437      AC H9G514.1
#=GS F6VEG2_MACMU/303-462      AC F6VEG2.1
#=GS L5L8Q0_PTEAL/391-550      AC L5L8Q0.1
#=GS A0A093ZD96_9PEZI/83-238   AC A0A093ZD96.1
#=GS W5LF66_ASTMX/255-415      AC W5LF66.1
#=GS A0A093BN37_CHAPE/292-455  AC A0A093BN37.1
#=GS G5BZA2_HETGA/302-452      AC G5BZA2.1
#=GS A0A0F8XGQ6_9EURO/56-194   AC A0A0F8XGQ6.1
#=GS A0A0A0MUP9_PAPAN/320-479  AC A0A0A0MUP9.1
#=GS CAF1A_MOUSE/299-458       AC Q9QWF0.1
#=GS F6X520_CANLF/323-481      AC F6X520.1
#=GS M0R3S3_RAT/301-451        AC M0R3S3.2
#=GS G1MUV9_MELGA/293-455      AC G1MUV9.2
#=GS A0A094BYL8_9PEZI/83-239   AC A0A094BYL8.1
#=GS E7FAY6_DANRE/323-371      AC E7FAY6.1
#=GS A0A067R7P4_ZOONE/356-518  AC A0A067R7P4.1
#=GS A0A0L9SZT9_9HYPO/56-209   AC A0A0L9SZT9.1
#=GS C1H0H5_PARBA/128-255      AC C1H0H5.1
#=GS C1GJR6_PARBD/131-255      AC C1GJR6.1
#=GS G3XLS4_ASPNA/102-247      AC G3XLS4.1
#=GS L5MGP6_MYODS/304-463      AC L5MGP6.1
#=GS T0NQ02_9CETA/264-415      AC T0NQ02.1
#=GS H2NX28_PONAB/319-478      AC H2NX28.1
#=GS A0A087XMB6_POEFO/256-422  AC A0A087XMB6.2
#=GS H0YRC7_TAEGU/282-445      AC H0YRC7.1
#=GS F7F7P0_MONDO/380-539      AC F7F7P0.2
#=GS G1QFV9_MYOLU/312-385      AC G1QFV9.1
#=GS F1P5R3_CHICK/293-456      AC F1P5R3.1
#=GS I3J2Y3_ORENI/277-443      AC I3J2Y3.1
#=GS F6VEI3_MACMU/302-461      AC F6VEI3.1
#=GS L8Y2Y3_TUPCH/314-473      AC L8Y2Y3.1
#=GS Q0CE47_ASPTN/117-246      AC Q0CE47.1
#=GS E7QAE9_YEASB/90-265       AC E7QAE9.2
#=GS F6VDM1_CALJA/418-462      AC F6VDM1.1
#=GS CAF1A_HUMAN/320-479       AC Q13111.2
#=GS H2VC85_TAKRU/227-396      AC H2VC85.1
#=GS U3JEF1_FICAL/280-443      AC U3JEF1.1
#=GS F6VDV6_CALJA/322-374      AC F6VDV6.1
#=GS H0VJM6_CAVPO/382-474      AC H0VJM6.1
#=GS G1MUW3_MELGA/290-451      AC G1MUW3.2
#=GS T1ENS0_HELRO/71-218       AC T1ENS0.1
#=GS A0A0F2M3B9_SPOSC/274-383  AC A0A0F2M3B9.1
#=GS M3Y0Y1_MUSPF/425-584      AC M3Y0Y1.1
#=GS K7E9K7_ORNAN/11-170       AC K7E9K7.1
#=GS H0WK89_OTOGA/314-473      AC H0WK89.1
#=GS W5PIZ1_SHEEP/321-480      AC W5PIZ1.1
#=GS W5MI24_LEPOC/244-399      AC W5MI24.1
#=GS G3VAZ2_SARHA/1-150        AC G3VAZ2.1
#=GS G3SLF5_LOXAF/298-355      AC G3SLF5.1
#=GS A0A0P7TXQ7_9TELE/197-362  AC A0A0P7TXQ7.1
#=GS F7C253_HORSE/307-466      AC F7C253.1
#=GS A0A0D9RDU6_CHLSB/302-461  AC A0A0D9RDU6.1
#=GS H2MK30_ORYLA/6-102        AC H2MK30.1
I3MNS2_ICTTR/301-455                 ...................................tpvhri--TKKFVKGSTEKNRMRPQR....-.--.------........DKEQLREEKEKLKEEAR----RAK.EEARRKK.EEEKELKE....KE..RRE.KRE......KDE.KER..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
G1L5F6_AILME/308-467                 .........................................RITKKLVKASAEKDKLRLQR....D.KE.RLGKQL........KLRAKKEEKEKLKEEAK----RAK.EEARKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
H3D6M0_TETNG/258-388                 ..............................hkcfqkpktsp--------------------....-.--.------........---------------------KIP.EDQRKSKrRSLRNLQE....QE..EKL.RKA......KEE.LKK..S-KLEF-EWAH.WM.FLSCLR.....AKQEEKRKKE...EEKR.MKEEEkrl.....keekDRLKAE.KA..E.....ITRFL..QK.P.KI........QQA.PKTL...AAACGKF.APFEIKENVYL............................................................
I3J2Y4_ORENI/239-403                 ................................padqkkvkr-RSLKS-----------LQE....Q.DE.RLRLRQ........EKERQKEEAKAAKEKKKEEARKLK.EEREREK.REKKEKDE....RE..KRE.KKE......KEE.REK..AERLKAKEELR.KS.KME---.....AKLEEKRKKE...EEKR.MKEEEkrl.....keekDRLKAE.KA..E.....ITRFL..QK.P.KI........QQA.PKTL...AAACGKF.APFEIKENMAL............................................................
A7F4P3_SCLS1/785-946                 ............................lvshyesfrddia-------------ERRHEEF....D.KR.RRDAEK........ELEKQVAQRRKEFKERKIREKRER.EEQERKL.REEEERAQ....KE..KAE.KDE......REE.KRK..AEFAQLKAIRE.KE.RQEALE....iAALQERRAEE...ASKR.RAEEK............ARGPVR.GA..P.....IERS-..DS.T.GE........RRA.PLAL...AGASGKI.N----------wrekerlr....................................................
M3WK65_FELCA/323-468                 .........................................RITKKLVKASAEKDKLRLQR....D.RE.RLGKQL........KLRAEKEEKEKLKEEAK----RAK.EEAKKKK.EEEKE---....--..---.---......---.XEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
F1S7L7_PIG/321-480                   .........................................RMSNKLLKGSAEKNKMRLQR....D.KE.RLGKQL........KLRAEKEEKEKLREEAK----RAK.EEAKKKK.EEEKELKE....RE..RRE.KRE......KDE.KEK..AEKQRRKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
G3HCF9_CRIGR/291-444                 ...............................pickvnkklv----------------RGST....E.KG.RSKLHR........DREQQREEKEKLREETR----QAK.EEARRRK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
M3XIX8_LATCH/306-469                 .........................................KGSQNSSKSKGLKEKRRLEK....E.QE.REEKRK........KLQAEKEEKERLREEVKAVKERAK.EEAKKKK.EEEKEQKE....KE..RKE.KKE......KEE.KEK..AEKLRLKEEKR.KE.KQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRIKAE.KA..E.....ITRFL..QK.S.KT........PQV.PKTL...AGSCGKF.APFEIKENMVL............................................................
G1PI42_MYOLU/1-141                   ........................................q--------------------....D.KE.RLGKQL........KLQAEKEEKEKLKEEAK----RAK.EEARRRR.EEEKELKE....KE..RRE.KRE......KEE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQT.PKTL...AGSCGKF.APFEIKENMVL............................................................
A0A091DEY6_FUKDA/295-447             .....................................vrri--TKKCVKGSTEKSKLKLQR....-.--.------........GKEQLREEKEKLK----EEARRAR.EEARRRK.EQEKELKE....KE..RRR.KRE......KDE.KER..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...KEKR.LREEE............KRLKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKERMVL............................................................
G3SLF5_LOXAF/345-436                 ........................................a--------------------....-.--.------........------------------------.-------.--------....--..---.---......---.KEE..A-RKRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEEkvl.....rakvKRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIREHMVL............................................................
K7EPA1_HUMAN/93-245                  ...............................stspfptstp-----------------LRR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
V8NFM8_OPHHA/259-422                 .......................................na--ASKVHRISEEKEKLKLQR....D.QE.RAEKLQ........KLEAKREEKRQLKKEAQAAKERAR.EETKRKK.EEEKELKD....KE..RRE.KKE......KDE.KEK..AEKQRAKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRLKAE.KA..E.....ITRFF..QK.P.KT........QPA.PKTL...AGWCGKF.APFEIKENMVL............................................................
M4ABP2_XIPMA/235-394                 ...............................kipaeekkikRRSLKSLQEQ----------....-.EE.RLRLRQ........EKERQKEEAKAAKEKKKEEARMLK.EEKEREK.REKKEKEE....RE..KRE.KKE......KEE.KEK..AERLKAKEELR.KS.KLE---.....AKLEEKRKKE...EEKR.MKEEF............QRLKAE.KA..E.....ITRFL..QK.P.KI........QQA.PKTL...AAACGKF.APFEIKGNMSL............................................................
C4JLZ9_UNCRE/115-285                 ..................................egcrplv-----------KKQRPRKKQ....G.KT.RLANFW.......eEEKQKREEEKKRREEEREAEKRRR.EEVRKKK.EEEKEEEK....RK..REEeKKK......KDE.EKE..AER-KKREEKR.KQ.KEDERI.....AREEEKKKKE...RSQ-.-----............------.--..-.....-----..--.-.--........---.----...-------.-----------mrlnafftkpsipnstnkavepkaveesnqasasqspdtkavsdysdefppffvqshvcl
F6VDM1_CALJA/322-420                 .........................................RITKKFVKSPTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....Q---------...----.-----............------.--..-.....-----..--.-.--........---.----...-------.-----------r...........................................................
H2QF16_PANTR/320-479                 .........................................RITKKFVKGSTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
Q6FN62_CANGA/71-221                  .................................qssnggta--------SSSQSESRQSEK....N.RM.RELKRV........QREAEKLRREQLKAEEKLKKEKKK.EEERLRR.EEEKKKRE....EE..KRL.KEL......QRE.EEK..RKREQAKEEER.KK.KEQLRL.....QKEEEKRQKE...EEKR.LKEEA...........kERA---.QS..R.....IGNFF..RK.-.--........---.----...-------.-----------vsddanknvsrktdyek...........................................
C3YNV2_BRAFL/369-543                 ....................................rvktp----KQLAKEAELQRKREEK....E.KE.KQEKLR........LKEEERAEKERLRSEARRQKELEK.EELRKKK.EEEKRQKE....AE..KQK.LKE......AEE.KER..QEKLRIKEEER.KK.KQEAIE.....AKLEEKKKKE...EEKQ.KQEEEkkkv...eeekaRKQQKV.KA..A.....FQSFF..VK.P.KF........DPAePKEE...QQPVGAF.MPFEVKKDMKL............................................................
F6YQD7_XENTR/348-417                 .................................seslikts--------------------....-.--.------........------------------------.-------.--------....--..---.---......---.---..-----------.--.------.....-KATTRRHKD...TNMN.PSHCK............KRLKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTF...ARSCGKF.APFEIKKDMAL............................................................
CAF1A_DANRE/242-396                  ....................................ankvkRRSLKSVQEQEEKQRQRDEK....-.--.------........--ERLKQEAKAAKEKKKEEARKMK.EEKEREK.KEKKEKDE....KE..RRE.KKE......RDE.KEK..ADKLKAKEEQR.QM.KIE---.....AKLEEKRKKE...EEKR.LKEEK............DRIKAE.KA..E.....ITRFL..QK.P.KT........QLA.PKTL...ASACGKF.APFEIKAHMSL............................................................
U3JEF0_FICAL/283-446                 ........................................k-VPQKFHRSSAEKEKLRLQR....D.QE.RADKLQ........RLQAEREQKGRLKEEAKAAKERAK.EEAKKRK.EEEKELKE....RE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRLHAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKENMVL............................................................
H2ZYI8_LATCH/323-486                 .........................................KGSQNSSKSKGLKEKRRLEK....E.QE.REEKRK........KLQAEKEEKERLREEVKAVKERAK.EEAKKKK.EEEKEQKE....KE..RKE.KKE......KEE.KEK..AEKLRLKEEKR.KE.KQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRIKAE.KA..E.....ITRFL..QK.S.KT........PQV.PKTL...AGSCGKF.APFEIKENMVL............................................................
U7PT59_SPOS1/274-383                 ............................ivyeyvesggmdk--------------------....-.--.------........------------------------.-ERARVR.HSKTWQGQ....QR..AKA.KAE......AEA.KE-..ALAVGVETRNQ.RA.QREALA.....ARQKEQKEKQ...RQER.LKEDQ............QQEHDR.VA..A.....VARFL..HL.A.GI........SFC.PQSL...AC-----.-----------nwkn........................................................
CAF1A_BOVIN/322-481                  .........................................RITKKLVRGSAEKNKMKLQR....D.KE.RLRRQL........KLRAEKEEKEKLREEAK----RAK.EEARKKR.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
CAF1A_CHICK/293-456                  .........................................KVSQKLHKSSAEKEKLRLQR....D.QE.RADKLQ........KLQAEREEKGRLKEEAKAAKERAK.EEAKKKK.EEEKELKE....RE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKIL...AGSCGKF.APFEIKENMVL............................................................
M7AWT3_CHEMY/273-433                 ..........................qnrsdtsplaasipv------------------RK....D.QE.RADKLQ........KLQAEKEEKGRLKEEAKAAKERAK.EEAKKKK.EEEKELKE....KE..RRE.KKE......KDE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKENMVL............................................................
G7PYM2_MACFA/284-435                 ...............................tspfptstpv------------------RR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
U3IL50_ANAPL/273-437                 ........................................k-VPQKFPKSSAEKEKLRLQR....Q.TL.PERVGA........AREVHGHSRERLNLKEAAAARGAL.EQAALCE.WALQVLLV....LP..RKL.RCE......INK.KKR..EEVNAFRESRR.SEaEQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKIL...AGSCGKF.APFEIKENMVL............................................................
G3PN46_GASAC/1-96                    .......................................pr--------------------....-.--.------........------------------------.-------.--------....-R..RSS.KSE......QEE.KVRlqQEKERQKEETK.AA.KMK---.....IKEEARRVAE...IKVR.VSNAS............QRLKAE.KA..E.....ITRFL..QK.P.KI........QQP.PKTL...AAACGKF.APFEIKEHMAL............................................................
E9IDN8_SOLIN/240-437                 .etsseldksisnrneevtenkettpatsvtpktdknikri----------KRLTPKQLEK....R.EE.IARRKE........ERLKLKMEKEKKREEEKANRRREK.EEKQKEK.EEK-EKIE....KElkKKE.KELk...elKKQ.MEL..EQKQKEKEARE.EE.RKKREE.....AKEEEKRKKE...DE-R.LEAER............KKQKAV.SN..F.....VSFFV..PKkQ.EV........KSM.EEES...VVKVKNF.MPFEIKADMR-v...........................................................
G1QSB4_NOMLE/320-479                 .........................................RITKKFVKGPTKKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKRKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
Z4YIN8_DANRE/177-331                 ....................................ankvkRRSLKSVQEQEEKQRQRDEK....-.--.------........--ERLKQEAKAAKEKKKEEARKMK.EEKEREK.KEKKEKDE....KE..RRE.KKE......RDE.KEK..ADKLKAKEEQR.QM.KIE---.....AKLEEKRKKE...EEKR.LKEEK............DRIKAE.KA..E.....ITRFL..QK.P.KT........QLA.PKTL...ASACGKF.APFEIKAHMSL............................................................
S6ESZ0_ZYGB2/44-203                  ...........................qpngeqitkqqpea-------------QSLKGKSs..sT.GElVSTKKQ........EAQKEKERRKRQREEEKRRREQER.EDEKRRR.EEQKE-EE....KR..KRE.KRK......EDQ.KEK..REELKRRKESE.KR.QRE---.....---EEKLKKE...QEKK.LKQEA............KE--RS.QA..R.....IGNFF..KK.V.SD........SSK.QLNV...ASDYEKFfLPFYAKESVS-v...........................................................
J5RIC1_SACK1/96-259                  ...........kesigsdgnadkqrpgealsivsesksksp--------------------....-.--.------........SPSSKKEPSTMRKENAKME----K.ELKRQQR.EEEKHRKEllrqAE..RRK.KEL......KTE.EER..HKRAELKKQKE.EA.RLETKR.....RKEEEKSKKE...QEIR.LKEEA............KE--RA.QS..R.....IGNFF..KK.V.SD........SNA.PPVE...KSDYEKFfLPFYAKD----gvkv........................................................
F6VDV6_CALJA/367-455                 ......................................kra--------------------....-.--.------........------------------------.-------.--------....--..---.---......--K.EEA..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
W4YJY9_STRPU/299-469                 .......................................pm--SAKALQRLKEQEEKKEEK....L.KL.REDKKR........KLEEENEMKKRQKLEQKQAKEEEK.EAQRKEK.AEEKKKKE....ME..KQL.KKE......KEE.QER..MEKKKAKEEER.LK.KQEEIE.....AKQEEKKKKQ...EER-.IKQEE............EKKQKE.AA..E.....LSKKS..KQ.S.QVfknffsvqAQA.PVKK...PEVKGWF.APFEVKSDQVL............................................................
E7FAY6_DANRE/243-328                 .....................................nkvkRRSLKSVQEQEEKQRQRDEK....-.--.------........--ERLKQEAKAAKEKKKEEARKMK.EEKEREK.KEKKEKDE....KE..RRE.KKE......RDE.KEK..ADKLKAKEEQ-.--.------.....----------...----.-----............------.--..-.....-----..--.-.--........---.----...-------.-----------d...........................................................
B2GSW9_DANRE/242-396                 ....................................ankvkRRSLKSVQEQEEKQRQRDEK....-.--.------........--ERLKQEAKAAKEKKKEEARKMK.EEKEREK.KEKKEKDE....KE..RRE.KKE......RDE.KEK..ADKLKAKEEQR.QM.KIE---.....AKLEEKRKKE...EEKR.LKEEK............DRIKAE.KA..E.....ITRFL..QK.P.KT........QLA.PKTL...ASACGKF.APFEIKAHMSL............................................................
H9G514_ANOCA/261-437                 .........................................KVSQKTHQSAEEKEKLKLQKnildN.KE.GLRKSLlniklafaGQDQERAEKGRLKEEAKAAKERAR.EEARRKK.EEEKELKE....KE..RKE.KKE......KDE.KEK..AEKLRVKEEKR.KE.KQEALE.....AKLEEKRKKE...EEKR.LKEEE...........kRRIKAE.KA..G.....ITRFF..QK.P.KT........QPV.PKTL...AGWCGKF.APFEIKENMVL............................................................
F6VEG2_MACMU/303-462                 .........................................RITKKFVKGSTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
L5L8Q0_PTEAL/391-550                 .........................................RVTKKLVKDSAEKNKMRLQR....D.KE.RLGKQL........KLRAEKEEKEKLKEEAK----RAK.EEARKRR.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRRKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKENMVL............................................................
A0A093ZD96_9PEZI/83-238              ...............................smmsgsgqpp------------KKKPKLTY....A.EQ.EHKKILk......eIRDREKADERARKEAEKRDKEHDK.ARKDAEI.KAEKQRKE....AE..REE.KRL......MKE.AEK..AEKDKVKAEKD.KV.K----E.....AKDEEKRKKE...EEKQ.RHEEE............KRKKERsQK..K.....LNSFF..IS.Q.PA........KKA.EK--...-------.-----------dvspepgnaagvald.............................................
W5LF66_ASTMX/255-415                 ...................................prtdae-------QKKAKRRSLKSAQ....EmEE.KQRQRE........ERERLKEEARAAKEKKREDARRLK.EEKEKEK.KEKREKDE....RE..RRE.KKE......RDD.KEK..AEKQRAKEEQR.KV.KME---.....AKLEEKRKKE...EEKR.LREEK............DQIKAE.KA..A.....ITRFL..QK.S.KT........QLA.PKTL...ASVCGKF.APFEIKEHMIL............................................................
A0A093BN37_CHAPE/292-455             .........................................KVSQKCHRSSAEKEKLRLQR....D.QE.RADKLQ........KLQAEREEKGRLKEEAKAAKERAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKIL...AGSCGKF.PPFEIKENMVL............................................................
G5BZA2_HETGA/302-452                 ..................................vrritkk-----CIKGSTE--------....-.--.--KSKL........KLQRDKEQLREEKEKLKEEARRAK.EEARKKK.EEEKELKE....KE..RRK.KRE......KDE.KEK..AEQRLIKEXXX.--.XXXALE.....AKMEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
A0A0F8XGQ6_9EURO/56-194              ...................dqsqthpqmqmppaakkrkvsp--------------------....-.--.------........ASREARQQEKEAKEKLKLEERAKK.DEEKKAK.EEEKRKRD....AE..KEE.EKK......KRE.AGK..EEERKRKEEKR.KV.KEEEKA.....AKEEEKRKKE...EEKM.KKERA...........qTRLN--.--..-.....--AFF..--.-.--........---.----...-------.-----------mkpkptiiehpvssaggs..........................................
A0A0A0MUP9_PAPAN/320-479             .........................................RITKKFVKGSAEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
CAF1A_MOUSE/299-458                  ..............................acrvaknfvkg------------------ST....E.KG.RSKLHR........DREQQREEKEKLREEIR----RAK.EEARKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEEkrl.....reeeKRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
F6X520_CANLF/323-481                 .........................................RITKKLIKASAEKDKLRLQR....D.KE.RLGKQL........KLRAEKEEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EE-R.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
M0R3S3_RAT/301-451                   ...............................rvdknlvkgs----------TE--------....-.KG.KSKLHR........DKEQQREEKEKLREEI----RRAK.EEARRKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRRKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
G1MUV9_MELGA/293-455                 .........................................KVSQKLHKSSAEKEKLRLQR....D.QE.RADKLQ........KLQAEREEKGRLKEEAK-AAKRAK.EEAKKKK.EEEKELKE....KE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKIL...AGSCGKF.APFEIKENMVL............................................................
A0A094BYL8_9PEZI/83-239              ...............................smmsgggqpp------------KKKKKLTY...aE.QE.HN-KILk......eIRDREKADERARKEAEKRDKEHDK.ARKDAEI.KAEKQRKE....AE..REE.KRL......MKE.AEK..AEKDKVKAEKD.KV.K----E.....AKDEEKRKKE...EEKQ.RQEEE............KRKKERsQK..K.....LNSFF..IS.Q.PA........KKA.EK--...-------.-----------dvspepgnaagvaldd............................................
E7FAY6_DANRE/323-371                 ........................................a--------------------....-.--.------........------------------------.-------.--------....--..---.---......---.---..-----------.--.------.....----------...----.-KEEQ............DRIKAE.KA..E.....ITRFL..QK.P.KT........QLA.PKTL...ASACGKF.APFEIKAHMSL............................................................
A0A067R7P4_ZOONE/356-518             ..............................irnltpkqllk---------QLRSAKKKEEK....E.RQ.RQEREQ........KKAEEKEEREKKRAEEKEEKLRQK.LEKEEQK.K--KEKEE....KE..EQR.RKE......KEE.REE..IKK-KEKEEKE.RK.KQVELE.....IKNEEKRAKD...EEKR.KKEDK............R--QAE.IA..A.....FTSFFlpKK.A.ET........KPV.EEPK...AKAEENF.MPFEVKADMRL............................................................
A0A0L9SZT9_9HYPO/56-209              ...spqsasettspkqfnhdkqsvspsaatskatasatkpa--------------------....-.--.------........----------PQRKRLSAEEKQAR.EKDKAQK.QKEKEVQA....AL..RAA.DKA......RQE.EEK..VARAKEREEKR.KK.KEEEDM.....ARAEKKRKKE...EEQRrMQEDR............DKKARS.QT..R.....LNSFF..RL.P.NT........---.PKKT...AA-----.-----------epgshsasp...................................................
C1H0H5_PARBA/128-255                 ............................psvpnnkkrklsp--------------------....-.--.------........-------ATKLAKAQEKEAKERQR.AEEKAKK.EEEKKKRE....EE..RKK.---......-KE.EEK..EEERKKKEEKK.KS.KDEERL.....AREEEKRKKD...EEKM.KKE-R............SQMR--.--..-.....LNAFF..VK.P.AI........PSS.ATAG...NTSCGK-.-----------tmgnynvqn...................................................
C1GJR6_PARBD/131-255                 ............................svpnnkkrklspa--------------------....-.--.------........--------TKLAKAQEKEAKERRR.AEEKAKK.EEEKKR--....--..REE.ERK......KKE.EEK..EEERKKKEEKK.RT.KDEERL.....AREEEKRKKD...EEKT.KKERS...........qMRL---.--..-.....-NAFF..VK.P.AT........PSS.ATAG...NTSCGK-.-----------tmgnynv.....................................................
G3XLS4_ASPNA/102-247                 ........................aatttaapaakkrklsp--------------------....-.--.ASKEAK........QQEKEARERQKLEEKAKKEEEKAKrEEEKAKK.EEEKRKRE....AE..KEE.EKR......EEE.KKK..RE--AEKEEER.KK.KEEKRK.....VKEEEKAAKE...EEKR.KKEEE............-KLKKE.RAqtK.....LNSFF..AK.P.KT........PAQ.PS--...-------.-----------ssnttlsp....................................................
L5MGP6_MYODS/304-463                 .........................................RITKKLVKGSAEKNKMRLQR....D.KE.RLGKQL........KLQAEKEEKEKLKEEAK----RAK.EEARRRR.EEEKELKE....KE..RRE.KRE......KEE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQT.PKTL...AGSCGKF.APFEIKENMVL............................................................
T0NQ02_9CETA/264-415                 ..............................grqaelwlvsv-------------------Q....D.KE.RLGKQL........KLRAEKEEKEKLREEAK----RAK.EEARKKK.EEEKELKE....RE..RRE.KRE......KDE.KEK..AEKQRRKEARR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
H2NX28_PONAB/319-478                 .........................................RITKKFVKGSTEKNKLRLQR....D.QE.RLGKKL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
A0A087XMB6_POEFO/256-422             ...............................kipaeekkikRRSLKSLQEQ----------....-.EE.RLRLRQ........EKERQKEEAKAAKEKKKEEARKLK.EEKEREK.REKKEKEE....RE..KRE.KKE......KEE.KEK..AERLKAKEELR.KS.KLE---.....AKLEEKRKKE...EEKR.MKEEEkrl.....keekDRLKAE.KA..E.....ITRFL..QK.P.KV........QQA.PKTL...AAACGKF.APFEIKENMSL............................................................
H0YRC7_TAEGU/282-445                 .......................................qv--PQKFHRSSAEKEKLRLQR....D.QE.RADKLQ........KLQAEREEKGRLKEEAKAAKERAK.EEAKKRK.EEEKELKE....KE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIRENMVL............................................................
F7F7P0_MONDO/380-539                 ........................................k-VPRKLIKNSAEKGKMRLQR....D.KE.RLDKQL........KLQAEKEEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKLRLKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKENMVL............................................................
G1QFV9_MYOLU/312-385                 .........................................RITKKLVKGSVEKNKMRLQR....D.KE.RLGKQL........KLQAEKEEKEKLKEEAK----RAK.EEARRRR.EEEKELKE....KE..RRE.KRE......KE-.---..-----------.--.------.....----------...----.-----............------.--..-.....-----..--.-.--........---.----...-------.-----------............................................................
F1P5R3_CHICK/293-456                 .........................................KVSQKLHKSSAEKEKLRLQR....D.QE.RADKLQ........KLQAEREEKGRLKEEAKAAKERAK.EEAKKKK.EEEKELKE....RE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKIL...AGSCGKF.APFEIKENMVL............................................................
I3J2Y3_ORENI/277-443                 ..............................kipadqkkvkr-RSLKS-----------LQE....Q.DE.RLRLRQ........EKERQKEEAKAAKEKKKEEARKLK.EEREREK.REKKEKDE....RE..KRE.KKE......KEE.REK..AERLKAKEELR.KS.KME---.....AKLEEKRKKE...EEKR.MKEEEkrl.....keekDRLKAE.KA..E.....ITRFL..QK.P.KI........QQA.PKTL...AAACGKF.APFEIKENMAL............................................................
F6VEI3_MACMU/302-461                 .........................................RITKKFVKGSTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
L8Y2Y3_TUPCH/314-473                 ........................................q-VTKRTAKGSTEKSKLKLQR....E.AE.RQDKQL........KLRAEREEKEKLKEEAK----RAK.EEARRRK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALG.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.RT........PQA.PKTL...AGSCGKF.APFEIKEHMAL............................................................
Q0CE47_ASPTN/117-246                 .............................aagpaakkrkls--------------------....-.--.------........----------PASREAKQQEKEAK.EKARLEE.RAKKEEER....RA..REE.EKR......KRE.AER..EEEKKKREEKR.KA.REEEKA.....AKEEEKRKKEaakEEER.RKKEE............DRLKKE.RA..Qp...kLNAFF..AK.P.KV........PV-.----...-------.-----------qassagvnasp.................................................
E7QAE9_YEASB/90-265                  ccknspiestkydrntnkqvpngniiaietksrssspcsxr--------------------....-.--.------........----------ELSSSKKEEAKREK.ELKKQQR.AEEKHRKE....LL..RXE.EKXkkelkvEEErQRR..AELKKQKEEEK.RR.KEE---.....ARLEAKRRKE...EERL.KKEEE............IRLKEE.AK..EraqsrIGNFF..KK.L.SD........SNT.PVVE...KSDYEKFfLPFYAKD----gvrv........................................................
F6VDM1_CALJA/418-462                 .........................................--------------------....-.--.------........------------------------.-------.--------....--..---.---......---.---..-----------.--.------.....----------...----.----E............QRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
CAF1A_HUMAN/320-479                  .........................................RITKKFVKGSTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
H2VC85_TAKRU/227-396                 ............................tttntvhdekkikRRSL-----------KSLQE....Q.EE.RLRLQQ........EKQRQKEEAKAVKEKKKEEARKIK.EERQREK.REKKEKEE....RE..RRE.KKE......KDE.KEK..AERLKAKEDLK.KS.KLE---.....AKQEEKRKKE...EEKR.MKEEEkrl.....keekDRLKAE.KA..E.....ITRFL..QK.S.KI........QQA.PKTL...AAACGKF.APFEIKENVYL............................................................
U3JEF1_FICAL/280-443                 ........................................k-VPQKFHRSSAEKEKLRLQR....D.QE.RADKLQ........RLQAEREQKGRLKEEAKAAKERAK.EEAKKRK.EEEKELKE....RE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRLHAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKENMVL............................................................
F6VDV6_CALJA/322-374                 .........................................RITKKFVKSPTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAKRA----K.EE-----.--------....--..---.---......---.---..-----------.--.------.....----------...----.-----............------.--..-.....-----..--.-.--........---.----...-------.-----------aa..........................................................
H0VJM6_CAVPO/382-474                 .....................................sqdr--------------------....-.--.------........------------------------.-------.--------....--..---.---......---.---..--EQRRREERR.RE.RQEALD.....ASA---RRDS...PGPR.LGDPGqlpelsalllypQRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGNF.APFEIKEHMVL............................................................
G1MUW3_MELGA/290-451                 .........................................KVSQKLHKSSAEKEKEIAKK....S.-Q.SVLTSQ........KLQAEREEKGRLKEEAK-AAKRAK.EEAKKKK.EEEKELKE....KE..RRE.KKE......KEE.KEK..AEKLRVKEEKR.KE.RQEALE.....AKLEEKRKKE...EEKR.LKEEE............KRINAQ.KA..E.....ITRFF..QK.P.KT........PQA.PKIL...AGSCGKF.APFEIKENMVL............................................................
T1ENS0_HELRO/71-218                  .......................ddenftalnksqllnlng--------------------....-.--.------........----------VKKEAEKLEQLKNK.EMKERQK.QEEKEKKE....KE..KNE.LKM......RKE.KEK..EDKEREREEKR.RQ.KLEQVE.....EKKKKEEAKL...EGKR.KKEEE...........kNKTEKE.KQ..L.....MQNFF..IK.TtKK........QTA.ISTKqpnDSVNPLF.MPFELKSDMRL............................................................
A0A0F2M3B9_SPOSC/274-383             ............................ivyeyvesggmdk--------------------....-.--.------........------------------------.-ERARVR.HSKTWQGQ....QR..AKA.KAE......AEA.KE-..ALAVGVETRNQ.RA.QREALA.....ARQKEQKEKQ...RQER.LKEDQ............QQEHDR.VA..A.....VARFL..HL.A.GI........SFC.PQSL...AC-----.-----------nwkn........................................................
M3Y0Y1_MUSPF/425-584                 ........................................r-RITKKLKASAEKDKLKLQR....D.RE.RLGKQL........KLRAEKEEKEKLKEEAK----RAK.EEARKKR.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRRKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
K7E9K7_ORNAN/11-170                  ......................................qip---KKLISSSAERDKLRLQR....D.QE.RLGKQL........KLQAEKEEKEKLKEEAK----RAR.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKLRLKEEKR.KE.RQEALE.....AKLEEKRKKE...QEKR.LKEEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PAA.PKTL...AGSCGKF.APFEIKENMGL............................................................
H0WK89_OTOGA/314-473                 .........................................RITKRFLKVSTEKNQIKLQR....D.QE.RLGRQL........KLRAKREEKAKLKEEAK----RAK.EEAKKRK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKLRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
W5PIZ1_SHEEP/321-480                 .........................................RITKKLVRGSAEKNKMKLQR....D.KE.RLWRQL........KLQAEKEEKEKLREEAK----RAK.EEARKKR.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
W5MI24_LEPOC/244-399                 ..................................apgstat---------EDKKVKRRSLK...qG.EE.QEQRRR........QREEQRAEREQQRSEARAARERAK.EEARRRR.EE----KE....RD..KRE.KKE......KEE.KEK..AEKLRAKEEQR.KV.KLE---.....AKLEEKRKKE...EEKR.LKEEK............DRIKAE.KA..E.....ITRFL..QK.P.KT........LQV.PKTL...AAACGKF.APFEIKENMVL............................................................
G3VAZ2_SARHA/1-150                   .........................................---------------MKLQR....D.KE.RLDKQL........KLQAEKEEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KKE......KDE.KEK..AEKLRLKEEKR.KE.RQEALDeraekAKLEEKRKKE...EEKR.LKEEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKENMVL............................................................
G3SLF5_LOXAF/298-355                 .........................................RITKKCIKGSTEKNKIRLQR....D.KE.RLGKQL........RLQAEKEEKEKLKEEAK----RAK.EEARKRL.KE------....--..---.---......---.---..-----------.--.------.....----------...----.-----............------.--..-.....-----..--.-.--........---.----...-------.-----------............................................................
A0A0P7TXQ7_9TELE/197-362             .................................adlktnan--------TAEKKLKRRSLKi..sE.EE.RRQKQEe.....qlERNRQRQEAKAAKERKREEARKLK.EEREREK.KEKKEREE....RE..KRE.RKE......REE.KEK..AEKQRVKEEQR.KV.KQE---.....AKLEEKRKKE...EEKR.LKEEK............DRIKAE.KA..E.....ITRFL..QK.P.KT........LQA.PKTL...AAACGKF.APFEIKENMF-m...........................................................
F7C253_HORSE/307-466                 .........................................RITKKLVKGSAEKNRMRLQR....D.QE.RLGKQL........KLQAEREEKEKLREEAK----RAK.EEARKRR.EEERELKE....KE..RRE.RRE......KDE.KQK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
A0A0D9RDU6_CHLSB/302-461             .........................................RITKKFVKGSTEKNKLRLQR....D.QE.RLGKQL........KLRAEREEKEKLKEEAK----RAK.EEAKKKK.EEEKELKE....KE..RRE.KRE......KDE.KEK..AEKQRLKEERR.KE.RQEALE.....AKLEEKRKKE...EEKR.LREEE............KRIKAE.KA..E.....ITRFF..QK.P.KT........PQA.PKTL...AGSCGKF.APFEIKEHMVL............................................................
H2MK30_ORYLA/6-102                   ......................................ptp--------------------....-.--.------........------------------------.-------.--------....--..-KN.TKR......RSL.KEH..DEKLRLRRKSKiEA.KLEEKR.....KREEEKRIKE...EEKR.LKEEK............DRLKAE.KA..E.....ITRFL..QK.S.KT........QQV.PKTL...AAACGKF.APFEIKENMAL............................................................
#=GC seq_cons                        ......................................................tp.+.p+....p.pc.+.tp..........chptc+EE+c+hKEEtK....RsK.EEt+++K.EEEKEh+E....+E..RRE.K+E......K-E.KEK..AEK.RhKEE+R.Kc.+pEsLE.....AKLEEKRKKE...EEKR.L+EEE............+RlKAE.KA..E.....ITRFF..QK.P.KT........sQA.PKTL...AuuCGKF.APFEIKEpMsL............................................................
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