#=GF ID   CBM27
#=GF AC   PF09212.14
#=GF DE   Carbohydrate binding module 27
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1oh4
#=GF GA   20.00 20.00;
#=GF TC   20.20 20.00;
#=GF NC   19.90 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF WK   Carbohydrate-binding_module
#=GF CL   CL0202
#=GF RN   [1]
#=GF RM   12791255
#=GF RT   Structural and thermodynamic dissection of specific mannan
#=GF RT   recognition by a carbohydrate binding module, TmCBM27. 
#=GF RA   Boraston AB, Revett TJ, Boraston CM, Nurizzo D, Davies GJ; 
#=GF RL   Structure. 2003;11:665-675.
#=GF DR   INTERPRO; IPR015295;
#=GF DR   SCOP; 1oh4; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family are carbohydrate binding modules that
#=GF CC   bind to beta-1, 4-manno-oligosaccharides, carob galactomannan,
#=GF CC   and konjac glucomannan, but not to cellulose (insoluble and
#=GF CC   soluble) or soluble birchwood xylan. They adopt a beta sandwich
#=GF CC   structure comprising 13 beta strands with a single, small
#=GF CC   alpha-helix and a single metal atom [1].
#=GF SQ   82
#=GS R5WMB0_9FIRM/553-718        AC R5WMB0.1
#=GS D9SU53_CLOC7/37-200         AC D9SU53.1
#=GS R9J0P8_9FIRM/380-546        AC R9J0P8.1
#=GS A0A1C7IAS4_9FIRM/264-436    AC A0A1C7IAS4.1
#=GS A0A1I7GAV0_9CLOT/230-382    AC A0A1I7GAV0.1
#=GS A0A1H8VH58_9FIRM/27-202     AC A0A1H8VH58.1
#=GS A0A089LQD8_9BACL/896-1080   AC A0A089LQD8.1
#=GS F4LJ28_TREBD/544-725        AC F4LJ28.1
#=GS A0A7W5GAY1_9BACL/851-1036   AC A0A7W5GAY1.1
#=GS C6IZG2_9BACL/4-118          AC C6IZG2.1
#=GS A0A0B0HWF8_9BACL/45-226     AC A0A0B0HWF8.1
#=GS A0A168PVW9_9BACL/902-1091   AC A0A168PVW9.1
#=GS A0A3S0YNH3_9BACL/895-1076   AC A0A3S0YNH3.1
#=GS A0A3S1DSV3_9BACL/900-1087   AC A0A3S1DSV3.1
#=GS A0A7G5BZR7_9BACL/870-1053   AC A0A7G5BZR7.1
#=GS C4IK30_CLOBU/113-266        AC C4IK30.1
#=GS A0A1M5UAT7_9CLOT/233-394    AC A0A1M5UAT7.1
#=GS A0A2N5N0K6_9BACL/905-1087   AC A0A2N5N0K6.1
#=GS E0I6M7_9BACL/866-1052       AC E0I6M7.1
#=GS A0A841RUS5_9BACI/473-683    AC A0A841RUS5.1
#=GS A0A7C8HGL5_9FIRM/35-202     AC A0A7C8HGL5.1
#=GS A0A0Q4R335_9BACL/872-1056   AC A0A0Q4R335.1
#=GS A0A7Z2ZM20_9BACL/34-207     AC A0A7Z2ZM20.1
#=GS A0A1I6PB75_9BACI/516-690    AC A0A1I6PB75.1
#=GS A0A328U3T3_9BACL/58-225     AC A0A328U3T3.1
#=GS W4QCM8_9BACI/2-168          AC W4QCM8.1
#=GS A0A1M6TBE4_9FIRM/198-372    AC A0A1M6TBE4.1
#=GS A0A1I7GAV0_9CLOT/398-565    AC A0A1I7GAV0.1
#=GS A0A1B8W3T6_9BACI/859-1043   AC A0A1B8W3T6.1
#=GS A0A1I4HP69_9BACI/513-686    AC A0A1I4HP69.1
#=GS A0A1R1EFJ1_9BACL/926-1096   AC A0A1R1EFJ1.1
#=GS A0A3A1R4Y3_9BACI/524-706    AC A0A3A1R4Y3.1
#=GS A0A8J4H156_9BACL/862-1042   AC A0A8J4H156.1
#=GS K0J0J2_AMPXN/513-684        AC K0J0J2.1
#=GS A0A6B8RHD4_9BACL/38-213     AC A0A6B8RHD4.1
#=GS A0A3R9M2W0_9BACI/42-216     AC A0A3R9M2W0.1
#=GS A0A2V3WG40_9BACI/511-684    AC A0A2V3WG40.1
#=GS A0A811UH55_CERCA/51-156     AC A0A811UH55.1
#=GS A0A4Y8Q9A8_9BACL/237-418    AC A0A4Y8Q9A8.1
#=GS A0A1I6KY92_9FIRM/52-225     AC A0A1I6KY92.1
#=GS H6NKY7_9BACL/905-1086       AC H6NKY7.1
#=GS A0A3R9M2W0_9BACI/1062-1244  AC A0A3R9M2W0.1
#=GS A0A1H8VHM2_9FIRM/27-203     AC A0A1H8VHM2.1
#=GS Q9X0V4_THEMA/496-665        AC Q9X0V4.1
#=GS A0A7Z2ZM20_9BACL/688-875    AC A0A7Z2ZM20.1
#=GS A0A3R9M2W0_9BACI/220-385    AC A0A3R9M2W0.1
#=GS A0A1M5UAT7_9CLOT/40-203     AC A0A1M5UAT7.1
#=GS A0A5J5GC43_9BACL/892-1076   AC A0A5J5GC43.1
#=GS A0A1H7D7F8_9FIRM/499-668    AC A0A1H7D7F8.1
#=GS A0A179T6M8_9BACI/506-682    AC A0A179T6M8.1
#=GS D9SWK5_CLOC7/44-222         AC D9SWK5.1
#=GS A0A841UCR7_9BACL/503-693    AC A0A841UCR7.1
#=GS A0A2V2YQ35_9BACL/31-201     AC A0A2V2YQ35.1
#=GS A0A433XNG6_9BACL/503-682    AC A0A433XNG6.1
#=GS A0A1I7GAV0_9CLOT/50-202     AC A0A1I7GAV0.1
#=GS A0A1M7LAK8_9FIRM/203-372    AC A0A1M7LAK8.1
#=GS A0A6B8RHD4_9BACL/212-385    AC A0A6B8RHD4.1
#=GS R7R2P5_9FIRM/287-451        AC R7R2P5.1
#=GS A0A4R2BB17_9BACI/524-706    AC A0A4R2BB17.1
#=GS A0A2J8GFN6_VIBDI/494-667    AC A0A2J8GFN6.1
#=GS E6TTJ7_EVAC2/517-690        AC E6TTJ7.1
#=GS D9TNY4_THETC/883-1064       AC D9TNY4.1
#=GS D9SLS9_CLOC7/45-222         AC D9SLS9.1
#=GS A0A3R9M2W0_9BACI/392-570    AC A0A3R9M2W0.1
#=GS A0A1H9ZBZ2_9FIRM/391-562    AC A0A1H9ZBZ2.1
#=GS A0A1I1BD36_9BACL/891-1078   AC A0A1I1BD36.1
#=GS A0A5S5C8Z9_9BACL/912-1093   AC A0A5S5C8Z9.1
#=GS A0A143Y1S6_9FIRM/37-204     AC A0A143Y1S6.1
#=GS A0A4V3WFK6_9BACL/902-1082   AC A0A4V3WFK6.1
#=GS A0A4Y8Q9U0_9BACL/422-606    AC A0A4Y8Q9U0.1
#=GS A0A0L6JW90_9FIRM/774-958    AC A0A0L6JW90.1
#=GS A0A098MFV3_9BACL/884-1071   AC A0A098MFV3.1
#=GS A0A7Z2VND7_9BACL/574-756    AC A0A7Z2VND7.1
#=GS A0A4Y8Q9A8_9BACL/34-210     AC A0A4Y8Q9A8.1
#=GS A0A1H2XV62_9FIRM/28-199     AC A0A1H2XV62.1
#=GS A0A7X2HAB5_9BACL/882-1068   AC A0A7X2HAB5.1
#=GS A0A1S8THZ4_9CLOT/39-206     AC A0A1S8THZ4.1
#=GS A0A6G8D7Y5_9VIBR/492-665    AC A0A6G8D7Y5.1
#=GS A0A1H8VH41_9FIRM/498-668    AC A0A1H8VH41.1
#=GS A0A3S1B4D1_9BACL/899-1081   AC A0A3S1B4D1.1
#=GS A0A449BLK6_9MOLU/539-718    AC A0A449BLK6.1
#=GS A0A1H8VH78_9FIRM/39-211     AC A0A1H8VH78.1
R5WMB0_9FIRM/553-718                   ..................................visdlssaedy---------.-.D.K..WST.E..A...G.YAYK.HGD..AA...NK......A....G..NA....T...P.....D...IS..YD.S....-......-AN.ERLKVS.V.D..YSadS..T..S...S...W..S..E....A.KV...K......C.....V......P......T......E......A.....MdvS..Q..Y..N.QLSV.D.IIY....P....A..K...-......-...L...K...G..S...K.....L......K.............FF-..-........-..-...-.-.-...A....DG....II....NK.D.TTI..DDDA...EDI.--..G......D.....GLK..K..VT...VT.M....G....F...T...P...T......D...K..pL....T..D...VTIGI..........IG.S.STS...F.KG...NVYLDNLVL---sqa..........
D9SU53_CLOC7/37-200                    ....................qtviysndfedasklpekktaadlv---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..-G.G....I......NGS.TALGFD.Y.T..FD..K..S..K...D...W..D..Qk..dI.QM...N......Y.....Q......Y......A......D......P.....I..T..A..G..A.KLSV.D.VIL....P....K..D...G......T...Y...N...G..T...L.....K......L.............QAAtqLg......aN..W...A.W.T...K....A-....--....TE.E.QSI..DLSK...FVV.VG..D......Y.....KVQ..TiqFT...FG.D....E....I...A...S...I......Q...G...L....N..S...IIVQV..........VG.N.YCD...Y.NG...KVLIDNVKLI--dg...........
R9J0P8_9FIRM/380-546                   .................................asgnvlasvevl---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..--.-....S......TGN.KAIKIP.V.D..LS..K..T..T...E...W..T..D....IfKV...Q......I.....Dlp..seY......A......K......Q.....I..S..E..K..V.VMSY.D.LYF....P....E..G...S......-...-...V...G..A...D.....F......N.............TMT..V........M..P...G.-.L...K....SG....KD....QT.W.VTV..KNGR...NYA.TE..NwaetdiE.....GYK..V..FH...VE.V....D....M...N...E...FttwdgeK...N...V....D..Y...AFSDItpvksvipclAG.N.TSK...Y.KG...HIYLDNLK----vka..........
A0A1C7IAS4_9FIRM/264-436               ....................................qkpasdvkv---------.-.-.-..WDFeD..D...T.VQGW.HFD..NS...WA......T....D..SY....H...G.....A...TE..DV.C....S......VED.GKLKVN.M.D..YS..G..D..V...Dn.gW..V..Q....P.AI...S......V.....S......P......E......Gg....iD.....F..S..G..S..A.MLGF.E.LYF....E....K..D...A......M...T...T...G..N...I.....T......I.............KGV..-........-..A...G.D.-...-....-V....LK....DQ.M.SGI..KNME...TED.LG..N......G.....LVK..A..-V...IN.F....E....I...D...S...A......A...A...NketpD..K...LMILM..........VG.N.NTD...Y.KG...ALYFDNIRLY--tp...........
A0A1I7GAV0_9CLOT/230-382               ................................gvlkstdvtaasl---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..--.-....E......EDN.TALKIK.S.K..FD..G..T..D...S...W..E..DnihqI.SY...K......T.....N......Y......T......K......D.....L..S..K..D..A.KIEY.D.III....P....T..A...N.....kS...F...T...G..Q...M.....K......G.............AGG..VtthdestdE..W...G.W.V...N....F-....--....-N.V.QDI..TSSD...FVD.MG..-......N.....GYS..K..VH...VA.Q....T....M...E..gE...V......K...G...L....F..K...IDLQI..........VA.W.ECT...Y.SG...DFYVDNIK----yse..........
A0A1H8VH58_9FIRM/27-202                ....................................pvaaatelt---------.-.-.V..WNF.A..Q...G.ADGW.ASG..GV...WN......Y....D..-G....A...P.....T...IS..YD.E....K......IGD.GSIKLD.V.D..FH..KkvK..E...S...W..S..E....V.KL...H......N.....S......A......I......D......Ssp.laL..D..G..C..D.LLTF.D.FYF....N....P..S...K......L...T...N...G..S...F.....K......A.............KIY..M........K..S...D.-.S...N....VE....VV....NV.C.PDI..NVLA...ASP.VE..G......T.....ELK..K..VK...VS.V....P....L...Q...A...V.....tA...K...V....V..Y...FDFSV..........VG.S.YTS...Y.KG...EIYVDNIALGK-r............
A0A089LQD8_9BACL/896-1080              .....................................vylnimei--------T.L.K.Q..FTF.D..S...D.IAGV.QSA..GV...YS......A....S..GN...mT...A.....S...LE..HS.D....W......NGD.GKLQAN.V.T..GL..V..Y..G...D..tW..Q..E....V.KI...G......L.....P......D......I......A......Es..vdL..K..K..V..N.RISF.D.AWI....P....L..A...S......G...E...E...A..A...K.....W......D.............ISA..A........A..D...A.K.L...S....VS....PSgeffAG.S.VNL..SDLE...KVT.VG..D......A.....VYG..K..FT...AT.I....N....LsdkD...V...T......D...S...A....T..G...LELSL..........VG.K.SLN...Y.DG...PLYIDNIRLI--na...........
F4LJ28_TREBD/544-725                   ...........................................va--NNVTYSL.F.K.T..FDF.K..D...S.ICDA.VSL..GG...YQ......A....E..LR....S...L.....S...HS..--.-....T......LNG.GMLRAD.A.L..YP..G..L..N...E...W..E..E....L.KI...K......F.....P......L......M......S......E.....V..A..E..A..A.KISF.T.VYL....E....K..Tl.aS......T...P...S...G..K...T.....K......Pedkl....pgaqhYVA..F........D..P...G.W.V...K....TG....LG....TQ.N.CEL..ANLE...TVI.LD.dG......K.....SYY..R..QT...CT.F....E....F...F...N...N......P...Q...Y....T..Q...ATVCP..........TL.G.YVS...Y.NG...PVYIDDINLYKK.............
A0A7W5GAY1_9BACL/851-1036              ...................................lafvkvdelp---------.L.R.S..YTF.D..E...Q.INGI.QNN..GT...WP......A....A..MG....L...S.....L...AH..-A.L....I......GGN.GMLQLN.V.TgaVP..G..D..-...N...W..Q..E....F.KL...E......L.....T......D......A......A......Ta..vpL..A..S..V..N.RVKW.D.VWI....P....A..S...A......G...A...A...G..AnasL.....R......T.............VVM..L........P..P...D.W.SdegK....YG....ML....TT.E.EKL..SELD...TVT.ID..G......V.....AYA..R..YT...AV.V....N....L...N...D...A......A...K...S....A..EatsIALSL..........IG.S.GLQ...L.DG...PIYVDNIELI--ss...........
C6IZG2_9BACL/4-118                     .......................................kalsdv---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..--.-....-......---.------.-.-..--..-..-..-...-...-..-..-....-.--...-......-.....-......-......-......-......D.....L..S..R..I..G.RLKL.S.ALI....P....A..S...L......A...G...Q...G..A...A.....I......Q.............AIA..M........Y..P..eD.WdR...K....YG....MD....AT.K.KTL..TDLE...QVT.VD..G......K.....TYY..K..YD...AV.I....E....L...D...D...V......QaaaD...A....T..G...LAVSL..........VG.S.YLS...Q.GGs.eSIYVDDLGLF--sa...........
A0A0B0HWF8_9BACL/45-226                ytfdtaadvegvqyngeytdsltethdgsvaysdfnggslvirap---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..--.-....-......---.------.-.H..LN..G..T..D...S...W..Q..E....L.KL...E......L.....K......NakakagA......S......S.....L..A..D..I..K.RLKM.D.VWV....P....A..S...A......GeasV...N...A..S...L.....R......A.............VGQ..L........P..P...D.W.S..nK....YG....MD....TT.Y.VPL..ASLP...KET.ID..G......V.....EYV..K..FS...PT.I....D....FtnaD...A...L......A...A...A....D..D...IALSI..........VG.S.GLD...A.GGealPVYVDNIRLYN-a............
A0A168PVW9_9BACL/902-1091              ........................................mvfvk-----VKEVlM.K.S..YTF.D..N...D.TEEV.ESV..GT...WS.....gA....N..ENgtsiV...L.....D...VE..HG.E....F......DSN.GALQLN.A.T.gLE..P..D..D...T...W..Q..E....L.KL...N......L.....S......N......V......A......Et..vkI..S..D..V..K.RVKL.D.LLI....P...vS..V...D......N...N..pD...A..T...V.....R......T.............MVL..L........P..P...D.YnI...K....FG....MD....ST.E.KKL..TSLN...KVTdTM..G......L.....EYY..R..YS...AS.V....D....L...T...DpalS......S...A...A....K..G...LSISI..........VG.N.GFS...F.DR...PIYVDNIQLF--sv...........
A0A3S0YNH3_9BACL/895-1076              .....................................tvfvkige-------IL.M.K.Q..YTF.D..S...D.TEGM.RNN..GS...YP......D....T..LS....L...-.....T...IE..HG.A....L......GNN.GALKLN.V.Q..GA..D..H..A...E..sW..Q..E....L.KL...A......F.....P......D......W......D......D.....IkiS..D..V..K.RIRF.D.AWI....P....S..S...A......GsedA...N...A..S...L.....M......G.............VAM..L........A..P...D.W.N...T....KY....GS....TS.E.LKL..ADLP...KET.ID..G......V.....EYA..K..YS...AT.I....D....L...NdpaK...S......A...E...A....T..T...LALSL..........VG.R.YLE...L.SG...AVYVDNIRLYS-t............
A0A3S1DSV3_9BACL/900-1087              ......................................fvkvgel--------L.I.K.QlaFDT.P..E...S.ITQI.QNN..GT...YP......S....T..IQ....M...E.....-...LG..HS.V....V......DGN.GKLEIG.V.SdgLV..A..S..D...T...W..Q..E....L.KL...E......L.....K......Ae....aL......Ag....vD.....L..A..E..V..T.RVKF.N.ALI....Pv.aaQ..N...D......D...N...N...A..A...I.....R......A.............VVM..L........P..D...D.WdG...K....YG....MD....TT.Y.KSL..SDLE...QVV.IE..G......V.....QYY..K..YE...IA.I....E....L...DnpeK...S......A...E...A....T..G...LAISL..........VG.S.GLV..sQ.DG..lSIYIDDVSLYS-t............
A0A7G5BZR7_9BACL/870-1053              ........................................tvfvk-----VDEIlM.K.S..FPF.D..S...N.ITGI.QNN..GT...YP......D....T..IG....L...T.....-...LS..HG.E....L......GGN.KALELS.V.S..NA..V..Y..S...D..tW..Q..E....L.KL...E......F.....S......N......L......S......Dt..vtI..A..D..V..K.RVKL.D.AWI....P....L..T...A......GsksA...N...A..S...I.....R......A.............IAM..L........P..G...D.WdT...K....YG....MT....TT.V.TKL..TDLP...TET.IG..G......I.....AYA..K..YS...PV.I....D....L...NdpaK...S......S...A...A....T..G...LALSL..........VG.S.ELN...H.NG...SIFVDNIRLF--sv...........
C4IK30_CLOBU/113-266                   .........................evnikgvdslksvsigklge---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..--.-....-......-SE.NALKVE.S.S..FD..G..T..T...D...W..D..S....N.KH...E......F.....T......F......Yeh..sdE......E.....I..P..S..G..S.MIQF.D.VLI....P....K..E..nE......K...Y...N...G..T...I.....K......Y.............SGG..I.......gD..K...D.W.N...W....KG....AG....YG.D.INS..KDFE...D--.-Q..G......N.....GYL..K..KT...VS.V....K....T..sD...S...S......D...G...L....T..K...VILQL..........SG.Y.ECT...Y.AG...DMYIDNIKLIK-a............
A0A1M5UAT7_9CLOT/233-394               ..................nplawsigwgtgflggdkdvsysedlk---------.-.-.-..---.-..-...-.----.---..--...--......-....-..--....-...-.....-...--..--.R....E......GNN.GSLKVQ.V.K..LN..L..-..S...S...W..T..E....A.NV...Q......A.....Y......L......M......D......KdmeinT..S..K..Y..K.KLYY.D.IYV....P....N..P...D......S...F...G...N..G...L.....K......L.............AEA..F........N..D...T.W.G...P....IK....-D....WE.D.VDL..KNVE...KVT.IN..N......V.....TYG..V..VH...RN.I....D....V...Q...V...A......N...V...H....K..K...LTLRI..........SS.Y.GSN...Y.TG...PRYIDDVRV---sp...........
A0A2N5N0K6_9BACL/905-1087              .....................................kipeaplg---------.-.-.E..YMF.D..E...G.LEGA.SSG..GG...WK......A....D..VG...eA...Q.....Q...VQ..WN.G....-......--G.GALKLD.V.G.gLD..P..A..E...T...W..Q..E....I.KL...Q......L.....Nga..aaKl....gL......A......D.....M..S..Q..V..R.RVKL.D.AYI....PldfaA..A...S......G...D...E...A..K...I.....Q......A.............FGM..L........P..P...D.FeA...K....YG....MG....TT.Q.VRL..SELP...TVT.VG..Q......Q.....VYA..H..YA...PE.F....D....L...TdlaK...L......Q...A...S....Q..E...LFVSL..........AG.S.GLS...G.AG...SVYIDRIGLY--st...........
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#=GC seq_cons                          .........................................h.ht............t.t..asF.s..p...s.htuh...s..Gs...a.......t....p...t..............t...lp..hs.t...........sss.GtLcls.l.s..hs..s..s..s...s...W..p..E....l.Kl...p......l.....s......s......h......s......s.....l..s..p..s..s.+lca.D.lal....P....s..s...s......t...t...s...u..s...l.....p......s.............hsh..l........s..s...s.W.s...c....hu....hs....ps.p.hpl..sshc...pls.ls..G......s.....sYt..K..hp...ss.l....s....l...s...s...s......s...s...s....s..p...lslul..........lG.s.shs...a.sG...slYlDNlpLh..s............
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