GenomeNet

Database: Pfam
Entry: CBP
LinkDB: CBP
Original site: CBP 
#=GF ID   CBP
#=GF AC   PF12192.7
#=GF DE   Fungal calcium binding protein
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2jv7
#=GF GA   25.00 25.00;
#=GF TC   25.20 25.20;
#=GF NC   24.90 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   19298372
#=GF RT   NMR structure of a fungal virulence factor reveals structural
#=GF RT   homology with mammalian saposin B.
#=GF RA   Beck MR, Dekoster GT, Cistola DP, Goldman WE;
#=GF RL   Mol Microbiol. 2009;72:344-353.
#=GF DR   INTERPRO; IPR022013;
#=GF CC   This domain is found in eukaryotes, and is approximately 60
#=GF CC   amino acids in length. There is a single completely conserved
#=GF CC   residue C that may be functionally important. This is a calcium
#=GF CC   binding domain from the fungal protein CBP (calcium binding
#=GF CC   protein). This protein is a virulence factor with unknown
#=GF CC   virulence mechanisms. CBP complexes as a highly intertwined
#=GF CC   homodimer. Each monomer is comprised of four alpha helices which
#=GF CC   adopt the saposin fold, characteristic of a protein family that
#=GF CC   binds to membranes and lipids.
#=GF SQ   49
#=GS A0A165DXU2_EXIGL/181-240  AC A0A165DXU2.1
#=GS A0A0C9TY04_9HOMO/20-76    AC A0A0C9TY04.1
#=GS M2R218_COCSN/80-140       AC M2R218.1
#=GS A0A0A1SRZ2_9HYPO/27-99    AC A0A0A1SRZ2.1
#=GS A0A0C9VCS8_9HOMO/20-79    AC A0A0C9VCS8.1
#=GS A0A0A1TBN2_9HYPO/14-92    AC A0A0A1TBN2.1
#=GS A0A178AGS5_9PLEO/30-107   AC A0A178AGS5.1
#=GS A0A0C9TLI7_9HOMO/20-79    AC A0A0C9TLI7.1
#=GS A0A0G2FLN2_9PEZI/75-128   AC A0A0G2FLN2.1
#=GS A0A0C3FN90_9HOMO/22-81    AC A0A0C3FN90.1
#=GS B8NW99_ASPFN/24-99        AC B8NW99.1
#=GS D8QCK5_SCHCM/44-110       AC D8QCK5.1
#=GS A0A0C9UK26_9HOMO/30-83    AC A0A0C9UK26.1
#=GS B8NE81_ASPFN/16-91        AC B8NE81.1
#=GS A0A135T8B6_9PEZI/43-113   AC A0A135T8B6.1
#=GS A0A0D9N673_ASPFA/17-91    AC A0A0D9N673.1
#=GS A0A0C9V9U8_9HOMO/20-79    AC A0A0C9V9U8.1
#=GS A0A0F0IAB9_ASPPU/17-93    AC A0A0F0IAB9.1
#=GS A0A0C3B4Z5_9HOMO/2-79     AC A0A0C3B4Z5.1
#=GS A6R5I8_AJECN/33-69        AC A6R5I8.1
#=GS D8QCK3_SCHCM/10-91        AC D8QCK3.1
#=GS T0KI11_COLGC/40-111       AC T0KI11.1
#=GS C1G5E4_PARBD/30-122       AC C1G5E4.1
#=GS D8QAZ8_SCHCM/21-84        AC D8QAZ8.1
#=GS A0A0G2J401_9EURO/26-91    AC A0A0G2J401.1
#=GS A0A0C3CNP1_9HOMO/62-140   AC A0A0C3CNP1.1
#=GS Q0U782_PHANO/26-107       AC Q0U782.2
#=GS D8Q8J7_SCHCM/23-82        AC D8Q8J7.1
#=GS A0A165J8V5_9BASI/26-89    AC A0A165J8V5.1
#=GS A0A0U1LVN4_9EURO/15-88    AC A0A0U1LVN4.1
#=GS F0UVX7_AJEC8/33-108       AC F0UVX7.1
#=GS A0A165HFD9_EXIGL/111-163  AC A0A165HFD9.1
#=GS W6YJN9_COCCA/43-115       AC W6YJN9.1
#=GS A0A0F4YDI2_TALEM/15-106   AC A0A0F4YDI2.1
#=GS A0A0L1J0F9_ASPNO/24-98    AC A0A0L1J0F9.1
#=GS A0A0L1JD36_ASPNO/16-91    AC A0A0L1JD36.1
#=GS A0A0F0IJY9_ASPPU/24-98    AC A0A0F0IJY9.1
#=GS A0A0C9W025_9HOMO/8-79     AC A0A0C9W025.1
#=GS A0A0C9VYY8_9HOMO/19-80    AC A0A0C9VYY8.1
#=GS A0A086SVY8_ACRC1/24-98    AC A0A086SVY8.1
#=GS D8QCK1_SCHCM/36-94        AC D8QCK1.1
#=GS C1H229_PARBA/30-122       AC C1H229.2
#=GS A0A166DCB0_9HOMO/8-84     AC A0A166DCB0.1
#=GS C6H3B8_AJECH/33-108       AC C6H3B8.1
#=GS A0A010SF34_9PEZI/42-112   AC A0A010SF34.1
#=GS A0A0F4Z2R4_TALEM/21-99    AC A0A0F4Z2R4.1
#=GS A0A086T102_ACRC1/22-98    AC A0A086T102.1
#=GS CBP1_AJECG/33-108         AC O42720.1
#=GS CBP1_AJECG/33-108         DR PDB; 2JV7 A; 1-76;
#=GS CBP1_AJECG/33-108         DR PDB; 2JV7 B; 1-76;
#=GS Q2TWZ3_ASPOR/24-95        AC Q2TWZ3.1
A0A165DXU2_EXIGL/181-240             ................iri------------------------SAKCNAFACVASYAGEIAACGAA..AAELGA.NPLADIACFAA..............LLNAESVAPV-----caaclsg............................
A0A0C9TY04_9HOMO/20-76               ............islhlir--------------------------SCDAGKCAVALGPAAVGCLAA..GVQIGV.DPIADAGCVAG..............VVDSAVNTS------ril................................
M2R218_COCSN/80-140                  ....qvgrcrnaiadlrrr-----------------------ELRGCDVFACISAGVSSAASCAAAaaAAEGGL.NKILS------..............---------------sslkiqint..........................
A0A0A1SRZ2_9HYPO/27-99               ...............rqdr--------LELFKNEAQIIHTDAAQAGCDWGKCITALAGETAACGAA..AVELGA.NIFADIACIAS..............VGGAINNAA------canc...............................
A0A0C9VCS8_9HOMO/20-79               ............mslhmir--------------------------DCDATTCAVDLGPTGAGCLSA..GAGLGK.SVSADAKCVAG..............IVKSAVSPPASCAGC...................................
A0A0A1TBN2_9HYPO/14-92               ..avsaadnaipagrvaim-------------KSAAEYNAQAAIAGCDWVNCISSLAGATAACAAA..FAQGAA.NPVLDLACLAS..............----VGSTGPACRGC...................................
A0A178AGS5_9PLEO/30-107              ...............vvrd-----TSAVNALQAQAQAFVDAKEAAGCSKLKCIAALAPTVVSCAAA..LAEAGL.NPIADAACLAT..............LANSSINPPESCTSC...................................
A0A0C9TLI7_9HOMO/20-79               .............mslhmv-------------------------RSCDVLSCAAGLGPVATGCVTA..AAQLGD.DPISDVSCLGT..............AIKSVASPPASCSGC...................................
A0A0G2FLN2_9PEZI/75-128              ................wcw----------------------------DFYKCIAALAPTVVACSTA..LASLGL.NPVADANCAAA..............AANNGINLPHACDGC...................................
A0A0C3FN90_9HOMO/22-81               ............ghtfmrr--------------------------GCEIAKCVAALAPSVVSCVSA..AAQEGL.DPISDAACLAS..............AANSIVNFPPSCD--qc.................................
B8NW99_ASPFN/24-99                   ..................s-ATNIQSAAD-INNIASAWTKAKEDDGCSWLACISSVVGQSATCAAA..AAELAL.NPIADVACVAG..............LGTMT----------lsggpags...........................
D8QCK5_SCHCM/44-110                  ...........asplvard--------------------QLADHISCPILDCAKGLASTVSACGKA..AISLGR.NVIADAQCLAQ..............AVKTVTNVPDACKQC...................................
A0A0C9UK26_9HOMO/30-83               ................gay----------------------------DEIACALGLGPTGAGCISA..AVEVGA.NPIADASCVAG..............ALKTAVSPPASCSGC...................................
B8NE81_ASPFN/16-91                   ............aapasta------QNLQDLQNNAAAFTEAKKAAGCDWLACVSSLAGESAACAAA..AAELGA.NPIADAACIAS..............VGTS----TASCK--kc.................................
A0A135T8B6_9PEZI/43-113              ....etsnnlgacnnaiak-------------------LRGHEARGCDVWSCIGAFAALIPACGAA..VDEFFL.NPLADVACIGA..............----VANFQGPCKGC...................................
A0A0D9N673_ASPFA/17-91               .............apasta------QNLQDVQNNAAAFTEAKKAAGCDWLACVSSLAGESAACAAA..AAELGA.NPIADAACIAS..............VGTS----TASCK--kc.................................
A0A0C9V9U8_9HOMO/20-79               ............mslhmvr--------------------------DCDALSCASGLGPIASGCVSA..ATQLGV.DPVSDVNCLGT..............VLNSVASPPASCSGC...................................
A0A0F0IAB9_ASPPU/17-93               .............apasta------QNLQDLQNNAAAFTEAKKAAGCDWLACVSSLAGESAACAAA..AAELGA.NPFADAACIAS..............VGTSTVEVD------kell...............................
A0A0C3B4Z5_9HOMO/2-79                ...........qftvvall---------TAFAASAYAIPTAHLARRCDVTGCAVSLGPTAVSCVTA..AVQDGL.DPLSDAGCLTS..............GASLGVNLPSSCSGC...................................
A6R5I8_AJECN/33-69                   ...................DQPSLDEAFNMYNEAVNVFMKVSSAADCDWP----------------..------.-----------..............---------------vsahfl.............................
D8QCK3_SCHCM/10-91                   ..........alaavasaa------PAADIISSEVVAGNQLADHISCPILDCAKSLASNVSSCGKA..VASLGR.NVIADAQCLAA..............AVSTIANAPDSCKQC...................................
T0KI11_COLGC/40-111                  .....cetsndlgacnnai-----------------TKLRGHEARGCDVWSCIGAFATVIPTCAAA..VDELFL.NPVADLACLGA..............VA----N--------fqgpckdc...........................
C1G5E4_PARBD/30-122                  ..................a-QPAVKHALGQFNQAVTMFEKATAAASCNWITCLESLAASSAACAAA..LGELGL.GMSFPMQRTITspltspvllllpqpAPRAARDASKSARGP...................................
D8QAZ8_SCHCM/21-84                   .........apvaeirtaq-------------------------IKCPIVECLAALAPTVAICGVA..AAQGGA.DVPNDVVCLAS..............AANSAVNFPDSCNQ-c..................................
A0A0G2J401_9EURO/26-91               ..................r-ATQVASAFADYKNAVNSIQALTASNGCNWVECIQSLSISSGSCIAA..LAELGL.EWPL-------..............---------------cghaqiqal..........................
A0A0C3CNP1_9HOMO/62-140              mkpaitliaafaastlssp-------------------THVHNMRSCLWTQCLVALSPAALTCVPA..GIELGA.DFLIDGACLAN..............LGYDVVDAPGVCNGC...................................
Q0U782_PHANO/26-107                  ...........stsmvvrd-----TSAVSALQAQAETFLAAKEAAGCSKLKCIAALAPTAAACAAA..LAEAGL.NPLADAACLAT..............LANSVFNVPEPCKGC...................................
D8Q8J7_SCHCM/23-82                   .............vqreaq-------------------------LSCPIVECLAALAPAAAICGVA..AATLGR.DTAADVNCLAN..............AANAGVNFPDSCQQC...................................
A0A165J8V5_9BASI/26-89               ...........prartlql----------------------PVARSCSLLKCAVALGPTGLACVDA..AVEVGE.NPLADADCLLE..............AAEDVVDLSRAA---tk.................................
A0A0U1LVN4_9EURO/15-88               ................aaa--PAATNA-N-AKDAISTYHSTAAANGCNWLGCVSSLAGETAACAAA..AGEAGL.NPIADVACLAS..............----VGSAGSACKGC...................................
F0UVX7_AJEC8/33-108                  ...................DQPSVGDAFDKYNEAVKVFTQLSSAANCDWPACLSSLSASSAACIAA..IGELGL.DIPLDLACAAT..............---ATTSATQACKGC...................................
A0A165HFD9_EXIGL/111-163             ................lri------------------------SAKCNAFACVGAYAGEIAACGAA..AAELGA.NPLADIACFAA..............LLG------------aesvacq............................
W6YJN9_COCCA/43-115                  ........rcpanananqc-------------ASATAKLRLKEDNGCDVLACTVAAASTLTACTAA..VSEGGL.NPIADLACILA..............----AGISDVACKGC...................................
A0A0F4YDI2_TALEM/15-106              .falnaseaelnvaqndln---------------------ILQANGCSTLKCVSSLAGTTASCAAA..AAELGA.SMSLAVS----..............---------------lhverekeerkkwrltilslqtllltlpasapsap
A0A0L1J0F9_ASPNO/24-98               ..................s-ATNIQSAAD-IHNIASAWTKAKENDGCSWLACISSVVGQSATCAAA..AAELAL.NPIADVACVAG..............L-GTMTVACKPC---v..................................
A0A0L1JD36_ASPNO/16-91               ...........aapastaq-------NIQDVQSNAAAFMEAKKASGCDWLACVSSLAGESAACAAA..AAELGA.NPIADAACIAS..............VGTSTAS--------crkc...............................
A0A0F0IJY9_ASPPU/24-98               ..................s-ATNIQSAAD-INNIASAWAKAKEDDGCSWLACISSVVGQSATCAAA..AAELAL.NPIADAACVAG..............L-GTMTVACKPC---v..................................
A0A0C9W025_9HOMO/8-79                ...llslasvafaspislh-----------------------LARSCSAGKCAVALGPAGVGCIAA..AAQIGV.DPIADAGCVAG..............AVDSAVNVPDACSGC...................................
A0A0C9VYY8_9HOMO/19-80               ...........pmslhmvr--------------------------DCDALSCASGLGPIASGCVSA..ATQLGVgDPVSDVNCLGT..............VLNSVASPPASCSGC...................................
A0A086SVY8_ACRC1/24-98               .................ra--PEVTA-LD-ISKSAELYTSQLEAQGCNVWSCVVAAAPLLPICAAA..LIEP--.TPLGEIACIIA..............IVNLGTNKPAACNGC...................................
D8QCK1_SCHCM/36-94                   ............hiscplv---------------------------CNPQSCLGSLAPSVATCGAA..LATAGA.NIFADISCLTA..............AVKTVTSLPDSCKQC...................................
C1H229_PARBA/30-122                  ...................PKPAVTHALNEFKHAVTTFEKATSAASCDWITCLESLAASSAACAAA..LEELGL.SMPFPMQRTITspltlpvllllpqpAPKAARDASKSALGP...................................
A0A166DCB0_9HOMO/8-84                ......vfvafaasalaar---------------STPSRTLKERTDCQIANCVAALAGTVIGCTAA..ALQEGL.DPISDVSCLAA..............AVNTVLNFPASCD--qc.................................
C6H3B8_AJECH/33-108                  ...................DQPSVGDAFDKYNEAVKVFTQLSSAANCDWPACLSSLSASSAACIAA..IGELGL.DIPLDLACAAT..............---ATTSATQACKGC...................................
A0A010SF34_9PEZI/42-112              ....etsnnlgacnnaiar-------------------LRGHEARGCDVWSCIGAFAAVIPACGAA..VDELFL.NPLADVACLGA..............----VANFQGPCKGC...................................
A0A0F4Z2R4_TALEM/21-99               ................pgt---TASAAMQSVNDSANAAMKQLEALGCSYLKCVSALAGETAACGAA..AAELGA.NILADLACFAS..............VGNNIA---------gvdkdvfkn..........................
A0A086T102_ACRC1/22-98               ...........dkrapels-------ATD-IAKSAELYTSELEAQGCDLWGCIVAAAPLLPVCAAA..LIEP--.TPLGEIACIIA..............VVNLGTNKPAPCQGC...................................
CBP1_AJECG/33-108                    ...................DQPSVGDAFDKYNEAVRVFTQLSSAANCDWAACLSSLSASSAACIAA..VGELGL.DVPLDLACAAT..............---ATSSATEACKGC...................................
#=GR CBP1_AJECG/33-108         SS    ...................--SSHHHHHHHHHHHHHHHHHHHHHHT----HHHHHHTT--HHHHHH..HHSSSS.TTTTHHHHHHT..............---SSS---TTT-SS...................................
Q2TWZ3_ASPOR/24-95                   ..................s-ATNIQSAAD-INNIASAWTKAKEDDGCSWLACISSVVGQSATCAAA..AAELAL.NPIADVACVAG..............------LGTMTCFGN...................................
#=GC SS_cons                         ...................--SSHHHHHHHHHHHHHHHHHHHHHHT----HHHHHHTT--HHHHHH..HHSSSS.TTTTHHHHHHT..............---SSS---TTT-SS...................................
#=GC seq_cons                        .................ht....................t..tstuCshhsCluuLusssuuCuAA..uuELGh.sPluDsuClAu..............hhpsssshstsCp.....................................
//
DBGET integrated database retrieval system