GenomeNet

Database: Pfam
Entry: CBP
LinkDB: CBP
Original site: CBP 
#=GF ID   CBP
#=GF AC   PF12192.4
#=GF DE   Fungal calcium binding protein
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2jv7
#=GF GA   25.00 25.00;
#=GF TC   25.60 25.60;
#=GF NC   24.60 23.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   19298372
#=GF RT   NMR structure of a fungal virulence factor reveals structural
#=GF RT   homology with mammalian saposin B.
#=GF RA   Beck MR, Dekoster GT, Cistola DP, Goldman WE;
#=GF RL   Mol Microbiol. 2009;72:344-353.
#=GF DR   INTERPRO; IPR022013;
#=GF CC   This domain is found in eukaryotes, and is approximately 60
#=GF CC   amino acids in length. There is a single completely conserved
#=GF CC   residue C that may be functionally important. This is a calcium
#=GF CC   binding domain from the fungal protein CBP (calcium binding
#=GF CC   protein). This protein is a virulence factor with unknown
#=GF CC   virulence mechanisms. CBP complexes as a highly intertwined
#=GF CC   homodimer. Each monomer is comprised of four alpha helices which
#=GF CC   adopt the saposin fold, characteristic of a protein family that
#=GF CC   binds to membranes and lipids.
#=GF SQ   18
#=GS A0A010SF34_9PEZI/44-97  AC A0A010SF34.1
#=GS C1H229_PARBA/32-88      AC C1H229.1
#=GS C0RX53_PARBP/205-262    AC C0RX53.1
#=GS I8TNC7_ASPO3/26-82      AC I8TNC7.1
#=GS C6H3B8_AJECH/35-92      AC C6H3B8.1
#=GS W6YJN9_COCCA/45-100     AC W6YJN9.1
#=GS W7EZB3_COCVI/45-100     AC W7EZB3.1
#=GS T0KI11_COLGC/43-96      AC T0KI11.1
#=GS A6R5I8_AJECN/35-66      AC A6R5I8.1
#=GS F0UVX7_AJEC8/35-92      AC F0UVX7.1
#=GS D8QCK1_SCHCM/38-75      AC D8QCK1.1
#=GS Q0U782_PHANO/33-88      AC Q0U782.2
#=GS Q6TS31_PARBR/32-89      AC Q6TS31.1
#=GS Q2TWZ3_ASPOR/26-82      AC Q2TWZ3.1
#=GS B8NE81_ASPFN/19-76      AC B8NE81.1
#=GS CBP1_AJECG/35-92        AC O42720.1
#=GS CBP1_AJECG/35-92        DR PDB; 2JV7 A; 3-60;
#=GS CBP1_AJECG/35-92        DR PDB; 2JV7 B; 3-60;
#=GS B8NW99_ASPFN/26-82      AC B8NW99.1
#=GS C1G5E4_PARBD/32-87      AC C1G5E4.1
A0A010SF34_9PEZI/44-97             snnlgacnnaiarl------------------RGHEARGCDVWSCIGAFAAVIPACGAAVDELFLNPLADVA...
C1H229_PARBA/32-88                 ..............PAVTHALNEFKHAVTTFEKATSAASCDWITCLESLAASSAACAAALEELGLSMP----fpm
C0RX53_PARBP/205-262               ..............PAVKHALGQFNQVVTMFEKATAAASCNWITCLESLAASSAACAAALGELGLDIPLDLA...
I8TNC7_ASPO3/26-82                 ..............TNIQSAAD-INNIASAWTKAKEDDGCSWLACISSVVGQSATCAAAAAELALNPIADVA...
C6H3B8_AJECH/35-92                 ..............PSVGDAFDKYNEAVKVFTQLSSAANCDWPACLSSLSASSAACIAAIGELGLDIPLDLA...
W6YJN9_COCCA/45-100                ....panananqca------------SATAKLRLKEDNGCDVLACTVAAASTLTACTAAVSEGGLNPIADLA...
W7EZB3_COCVI/45-100                ....pakananqca------------SATAKLRLKEDNGCDVLACTVAAASTLTACTAAVSEGGLNPIADLA...
T0KI11_COLGC/43-96                 .sndlgacnnaitk-----------------LRGHEARGCDVWSCIGAFATVIPTCAAAVDELFLNPVADLA...
A6R5I8_AJECN/35-66                 ..............PSLDEAFNMYNEAVNVFMKVSSAADCDWP-----------------------------vsa
F0UVX7_AJEC8/35-92                 ..............PSVGDAFDKYNEAVKVFTQLSSAANCDWPACLSSLSASSAACIAAIGELGLDIPLDLA...
D8QCK1_SCHCM/38-75                 .........scplv-------------------------CNPQSCLGSLAPSVATCGAALATAGANIFADI-s..
Q0U782_PHANO/33-88                 .............d---TSAVSALQAQAETFLAAKEAAGCSKLKCIAALAPTAAACAAALAEAGLNPLADAA...
Q6TS31_PARBR/32-89                 ..............PAVKHALGQFNQVVTMFEKATAAASCNWITCLESLAASSAACAAALGELGLDIPLDLA...
Q2TWZ3_ASPOR/26-82                 ..............TNIQSAAD-INNIASAWTKAKEDDGCSWLACISSVVGQSATCAAAAAELALNPIADVA...
B8NE81_ASPFN/19-76                 .........astaq-----NLQDLQNNAAAFTEAKKAAGCDWLACVSSLAGESAACAAAAAELGANPIADAA...
CBP1_AJECG/35-92                   ..............PSVGDAFDKYNEAVRVFTQLSSAANCDWAACLSSLSASSAACIAAVGELGLDVPLDLA...
#=GR CBP1_AJECG/35-92        SS    ..............SSHHHHHHHHHHHHHHHHHHHHHHT----HHHHHHTT--HHHHHHHHSSSSTTTTHHH...
B8NW99_ASPFN/26-82                 ..............TNIQSAAD-INNIASAWTKAKEDDGCSWLACISSVVGQSATCAAAAAELALNPIADVA...
C1G5E4_PARBD/32-87                 ..............PAVKHALGQFNQAVTMFEKATAAASCNWITCLESLAASSAACAAALGELGLGM-----sfp
#=GC SS_cons                       ..............SSHHHHHHHHHHHHHHHHHHHHHHT----HHHHHHTT--HHHHHHHHSSSSTTTTHHH...
#=GC seq_cons                      ..............ssltpAhs.hppssssap+uppAsuCsWluCluSlAuoSAACuAAluELGLs..hDlA...
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