GenomeNet

Database: Pfam
Entry: CENP-H
LinkDB: CENP-H
Original site: CENP-H 
#=GF ID   CENP-H
#=GF AC   PF05837.8
#=GF DE   Centromere protein H (CENP-H)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_8705 (release 8.0)
#=GF GA   23.00 23.00;
#=GF TC   23.80 23.80;
#=GF NC   22.50 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   CENPH
#=GF RN   [1]
#=GF RM   10488063
#=GF RT   Characterization of a novel kinetochore protein, CENP-H. 
#=GF RA   Sugata N, Munekata E, Todokoro K; 
#=GF RL   J Biol Chem 1999;274:27343-27346.
#=GF RN   [2]
#=GF RM   11500386
#=GF RT   CENP-H, a constitutive centromere component, is required for
#=GF RT   centromere targeting of CENP-C in vertebrate cells. 
#=GF RA   Fukagawa T, Mikami Y, Nishihashi A, Regnier V, Haraguchi T,
#=GF RA   Hiraoka Y, Sugata N, Todokoro K, Brown W, Ikemura T; 
#=GF RL   EMBO J 2001;20:4603-4617.
#=GF DR   INTERPRO; IPR008426;
#=GF CC   This family consists of several eukaryotic centromere protein H
#=GF CC   (CENP-H) sequences. Macromolecular centromere-kinetochore
#=GF CC   complex plays a critical role in sister chromatid separation,
#=GF CC   but its complete protein composition as well as its precise
#=GF CC   dynamic function during mitosis has not yet been clearly
#=GF CC   determined. CENP-H contains a coiled-coil structure and a
#=GF CC   nuclear localisation signal. CENP-H is specifically and
#=GF CC   constitutively localised in kinetochores throughout the cell
#=GF CC   cycle. CENP-H may play a role in kinetochore organisation and
#=GF CC   function throughout the cell cycle [1]. This the C-terminus of
#=GF CC   the region, which is conserved from fungi to humans.
#=GF SQ   228
#=GS M9MD73_PSEA3/184-303      AC M9MD73.1
#=GS W3VR34_9BASI/184-299      AC W3VR34.1
#=GS A6DTA5_9BACT/51-160       AC A6DTA5.1
#=GS X0BXV4_FUSOX/124-227      AC X0BXV4.1
#=GS F0ZEI0_DICPU/174-272      AC F0ZEI0.1
#=GS G3QGP4_GORGO/139-239      AC G3QGP4.1
#=GS D8M956_BLAHO/143-243      AC D8M956.1
#=GS F2TJI4_AJEDA/140-243      AC F2TJI4.1
#=GS W6MKX9_9ASCO/125-232      AC W6MKX9.1
#=GS H2QR06_PANTR/139-239      AC H2QR06.1
#=GS C5P9N1_COCP7/136-238      AC C5P9N1.1
#=GS F7GDG6_ORNAN/107-207      AC F7GDG6.2
#=GS G0RDU4_HYPJQ/125-229      AC G0RDU4.1
#=GS A2QDK2_ASPNC/77-180       AC A2QDK2.1
#=GS C1BYA2_ESOLU/129-228      AC C1BYA2.1
#=GS C6HRL4_AJECH/140-243      AC C6HRL4.1
#=GS E9E019_METAQ/126-230      AC E9E019.1
#=GS G3J8R7_CORMM/143-240      AC G3J8R7.1
#=GS S3CBC6_OPHP1/206-307      AC S3CBC6.1
#=GS H0VRH0_CAVPO/1-95         AC H0VRH0.1
#=GS A8WHV8_DANRE/129-227      AC A8WHV8.1
#=GS X0LPP1_FUSOX/124-227      AC X0LPP1.1
#=GS U4LJT9_PYROM/163-262      AC U4LJT9.1
#=GS V5FDE0_BYSSN/134-237      AC V5FDE0.1
#=GS S3DE02_GLAL2/144-247      AC S3DE02.1
#=GS K1S4I7_CRAGI/459-554      AC K1S4I7.1
#=GS C1C429_LITCT/155-253      AC C1C429.1
#=GS G1QVE6_NOMLE/139-239      AC G1QVE6.1
#=GS N4TPR3_FUSC1/124-227      AC N4TPR3.1
#=GS A0A016PXT1_GIBZA/124-228  AC A0A016PXT1.1
#=GS L0PG58_PNEJ8/139-231      AC L0PG58.1
#=GS M1EJ07_MUSPF/121-213      AC M1EJ07.1
#=GS M7U4T3_BOTF1/129-233      AC M7U4T3.1
#=GS S9X945_SCHCR/106-212      AC S9X945.1
#=GS G7XPL2_ASPKW/132-235      AC G7XPL2.1
#=GS K9GST4_PEND1/188-291      AC K9GST4.1
#=GS Q4P7V5_USTMA/178-295      AC Q4P7V5.1
#=GS A0A058ZAT0_9EUKA/203-321  AC A0A058ZAT0.1
#=GS W6Q3I3_PENRO/137-240      AC W6Q3I3.1
#=GS E3QDF7_COLGM/124-228      AC E3QDF7.1
#=GS V5EX88_PSEBG/186-302      AC V5EX88.1
#=GS A0A022WAH9_TRIRU/134-237  AC A0A022WAH9.1
#=GS G2R207_THITE/121-225      AC G2R207.1
#=GS Q0CNP0_ASPTN/132-235      AC Q0CNP0.1
#=GS F2S7D6_TRIT1/134-237      AC F2S7D6.1
#=GS N4VG30_COLOR/126-230      AC N4VG30.1
#=GS F7HY66_CALJA/139-239      AC F7HY66.1
#=GS J4UP66_BEAB2/149-246      AC J4UP66.1
#=GS F8MZG8_NEUT8/99-203       AC F8MZG8.1
#=GS S8AGL4_DACHA/151-250      AC S8AGL4.1
#=GS M3ZY84_XIPMA/128-227      AC M3ZY84.1
#=GS S7MFI6_MYOBR/572-652      AC S7MFI6.1
#=GS G1X4K7_ARTOA/150-249      AC G1X4K7.1
#=GS W9L3C0_FUSOX/124-227      AC W9L3C0.1
#=GS E3RR68_PYRTT/165-266      AC E3RR68.1
#=GS I3K852_ORENI/132-230      AC I3K852.1
#=GS G3W0S9_SARHA/100-200      AC G3W0S9.1
#=GS G7P7N4_MACFA/139-239      AC G7P7N4.1
#=GS X0FGU5_FUSOX/124-227      AC X0FGU5.1
#=GS J9P5K5_CANFA/142-229      AC J9P5K5.1
#=GS L5KLI2_PTEAL/136-236      AC L5KLI2.1
#=GS C3YVM5_BRAFL/132-231      AC C3YVM5.1
#=GS W7LER0_GIBM7/124-227      AC W7LER0.1
#=GS E9C9D8_CAPO3/160-267      AC E9C9D8.1
#=GS W6YNJ3_COCCA/129-233      AC W6YNJ3.1
#=GS Q4RUR4_TETNG/34-133       AC Q4RUR4.1
#=GS A0A022YWV2_TRIRU/134-237  AC A0A022YWV2.1
#=GS CENPH_MOUSE/133-233       AC Q9QYM8.1
#=GS A0A059K9Y5_TRIRU/134-237  AC A0A059K9Y5.1
#=GS F7IJ38_CALJA/120-220      AC F7IJ38.1
#=GS G1PLH1_MYOLU/97-197       AC G1PLH1.1
#=GS G1KSK7_ANOCA/129-229      AC G1KSK7.2
#=GS A0A022VGW1_TRIRU/134-237  AC A0A022VGW1.1
#=GS G3Y3L7_ASPNA/134-237      AC G3Y3L7.1
#=GS C5JUC6_AJEDS/140-243      AC C5JUC6.1
#=GS E2R8X4_CANFA/135-234      AC E2R8X4.2
#=GS M3X519_FELCA/137-237      AC M3X519.1
#=GS A0A028JWP4_TRIRU/134-237  AC A0A028JWP4.1
#=GS E4UNM1_ARTGP/134-237      AC E4UNM1.1
#=GS W5ML56_LEPOC/132-231      AC W5ML56.1
#=GS N1R9G4_FUSC4/124-227      AC N1R9G4.1
#=GS H0ZVC1_TAEGU/75-174       AC H0ZVC1.1
#=GS M0R9L1_RAT/78-178         AC M0R9L1.1
#=GS W5P6W1_SHEEP/136-236      AC W5P6W1.1
#=GS G1L8V0_AILME/138-239      AC G1L8V0.1
#=GS W9MBK9_FUSOX/124-227      AC W9MBK9.1
#=GS N4XEX5_COCH4/146-250      AC N4XEX5.1
#=GS N1JMQ1_BLUG1/154-259      AC N1JMQ1.1
#=GS F2PHW1_TRIEC/134-237      AC F2PHW1.1
#=GS B9EMR0_SALSA/132-231      AC B9EMR0.1
#=GS A0A024SLG9_HYPJE/119-223  AC A0A024SLG9.1
#=GS Q0UIN8_PHANO/134-237      AC Q0UIN8.2
#=GS I2FUH6_USTH4/185-304      AC I2FUH6.1
#=GS F7BNS0_XENTR/139-237      AC F7BNS0.1
#=GS E5A8D5_LEPMJ/54-157       AC E5A8D5.1
#=GS J9MCS4_FUSO4/124-227      AC J9MCS4.1
#=GS A0A017SCB4_9EURO/133-236  AC A0A017SCB4.1
#=GS A1D6R3_NEOFI/132-235      AC A1D6R3.1
#=GS G9NA91_HYPVG/115-218      AC G9NA91.1
#=GS U7Q6J0_SPOS1/114-225      AC U7Q6J0.1
#=GS X0IDI1_FUSOX/124-227      AC X0IDI1.1
#=GS R8BT39_TOGMI/119-223      AC R8BT39.1
#=GS B3KVZ3_HUMAN/120-220      AC B3KVZ3.1
#=GS Q2UKQ1_ASPOR/160-263      AC Q2UKQ1.1
#=GS L5LYK0_MYODS/463-563      AC L5LYK0.1
#=GS B6Q331_PENMQ/136-239      AC B6Q331.1
#=GS J3P818_GAGT3/123-230      AC J3P818.1
#=GS F7GYV6_MACMU/139-239      AC F7GYV6.1
#=GS B0XXC4_ASPFC/132-235      AC B0XXC4.1
#=GS G9P907_HYPAI/119-223      AC G9P907.1
#=GS G2WZ89_VERDV/122-233      AC G2WZ89.1
#=GS B2WEL0_PYRTR/133-234      AC B2WEL0.1
#=GS L8H183_ACACA/175-303      AC L8H183.1
#=GS C5G7F8_AJEDR/140-243      AC C5G7F8.1
#=GS L2G9P6_COLGN/126-230      AC L2G9P6.1
#=GS C4JZ24_UNCRE/135-237      AC C4JZ24.1
#=GS A0A022UD38_9EURO/134-237  AC A0A022UD38.1
#=GS B6H4J5_PENCW/132-235      AC B6H4J5.1
#=GS F1M389_RAT/132-232        AC F1M389.2
#=GS A7RSC2_NEMVE/138-238      AC A7RSC2.1
#=GS A1CKR0_ASPCL/132-235      AC A1CKR0.1
#=GS Q5B994_EMENI/131-234      AC Q5B994.1
#=GS J3KC56_COCIM/136-238      AC J3KC56.1
#=GS W7EKX9_COCVI/129-233      AC W7EKX9.1
#=GS I8IF92_ASPO3/132-235      AC I8IF92.1
#=GS G2YBK7_BOTF4/129-233      AC G2YBK7.1
#=GS T5C4Z3_AJEDE/140-243      AC T5C4Z3.1
#=GS R0JZC6_SETT2/151-255      AC R0JZC6.1
#=GS L7HQQ2_MAGOY/154-260      AC L7HQQ2.1
#=GS A0A022Y2Q2_TRISD/134-237  AC A0A022Y2Q2.1
#=GS B7FSK2_PHATC/144-242      AC B7FSK2.1
#=GS C1G1C0_PARBD/79-182       AC C1G1C0.1
#=GS F6RXE0_XENTR/141-241      AC F6RXE0.1
#=GS F6PLT4_HORSE/138-238      AC F6PLT4.1
#=GS L7J0Z2_MAGOP/128-234      AC L7J0Z2.1
#=GS K0KLT4_WICCF/130-229      AC K0KLT4.1
#=GS R7YUA9_CONA1/136-239      AC R7YUA9.1
#=GS CENPH_BOVIN/136-236       AC Q3T0L1.1
#=GS F9G357_FUSOF/124-227      AC F9G357.1
#=GS H0WK59_OTOGA/138-238      AC H0WK59.1
#=GS D4B356_ARTBC/134-237      AC D4B356.1
#=GS B2AM45_PODAN/109-213      AC B2AM45.1
#=GS A0A022TWL2_TRIRU/134-237  AC A0A022TWL2.1
#=GS T0KFT4_COLGC/126-230      AC T0KFT4.1
#=GS A7E7B6_SCLS1/124-228      AC A7E7B6.1
#=GS S9PPG1_SCHOY/101-208      AC S9PPG1.1
#=GS Q6CEC4_YARLI/132-229      AC Q6CEC4.1
#=GS U3KP60_RABIT/136-236      AC U3KP60.1
#=GS C9SMQ0_VERA1/30-141       AC C9SMQ0.1
#=GS A0A015K5T7_9GLOM/152-253  AC A0A015K5T7.1
#=GS M4FRL0_MAGP6/123-229      AC M4FRL0.1
#=GS C0NUZ1_AJECG/140-243      AC C0NUZ1.1
#=GS K3V3C0_FUSPC/124-228      AC K3V3C0.1
#=GS M1WHU5_CLAP2/130-234      AC M1WHU5.1
#=GS K9F993_PEND2/188-291      AC K9F993.1
#=GS X0LST7_FUSOX/124-227      AC X0LST7.1
#=GS K7FU00_PELSI/85-165       AC K7FU00.1
#=GS W7I3G8_9PEZI/150-249      AC W7I3G8.1
#=GS M7T7G4_EUTLA/30-139       AC M7T7G4.1
#=GS G5BKN6_HETGA/100-200      AC G5BKN6.1
#=GS CENPH_HUMAN/139-239       AC Q9H3R5.1
#=GS M2TRP5_COCH5/129-233      AC M2TRP5.1
#=GS C3YVL8_BRAFL/23-105       AC C3YVL8.1
#=GS M3YT77_MUSPF/139-239      AC M3YT77.1
#=GS F0U813_AJEC8/140-243      AC F0U813.1
#=GS A0A010RMT7_9PEZI/126-230  AC A0A010RMT7.1
#=GS Q4WY32_ASPFU/132-235      AC Q4WY32.1
#=GS F0XUY0_GROCL/186-292      AC F0XUY0.1
#=GS X0AXK5_FUSOX/124-227      AC X0AXK5.1
#=GS I1RA59_GIBZE/124-228      AC I1RA59.1
#=GS K1XTB7_MARBU/123-227      AC K1XTB7.1
#=GS G2Q1Y8_THIHA/112-216      AC G2Q1Y8.1
#=GS C1C3S7_LITCT/89-187       AC C1C3S7.1
#=GS B8N1N6_ASPFN/132-235      AC B8N1N6.1
#=GS F7W180_SORMK/117-221      AC F7W180.1
#=GS W9IEY7_FUSOX/124-227      AC W9IEY7.1
#=GS E9EWB2_METAR/127-231      AC E9EWB2.1
#=GS Q0P4K1_XENTR/141-240      AC Q0P4K1.1
#=GS L8FV22_PSED2/137-241      AC L8FV22.1
#=GS D2H2T8_AILME/1-56         AC D2H2T8.1
#=GS A0A059JH45_9EURO/134-237  AC A0A059JH45.1
#=GS W5KVX7_ASTMX/129-227      AC W5KVX7.1
#=GS R7T969_CAPTE/150-250      AC R7T969.1
#=GS F6QC79_MONDO/99-199       AC F6QC79.1
#=GS W6Z635_COCMI/143-247      AC W6Z635.1
#=GS FTA3_SCHPO/107-208        AC O94261.1
#=GS S0DJP0_GIBF5/124-227      AC S0DJP0.1
#=GS V9L3I7_CALMI/143-242      AC V9L3I7.1
#=GS A0A024JL95_GEOCN/237-335  AC A0A024JL95.1
#=GS A6QRL1_AJECN/112-206      AC A6QRL1.1
#=GS H2PFR2_PONAB/139-239      AC H2PFR2.1
#=GS C0S3I9_PARBP/143-246      AC C0S3I9.1
#=GS B8M4Y6_TALSN/136-239      AC B8M4Y6.1
#=GS W4YCN7_STRPU/163-260      AC W4YCN7.1
#=GS R9NVN9_PSEHS/188-302      AC R9NVN9.1
#=GS B6K0U9_SCHJY/120-223      AC B6K0U9.1
#=GS Q7S057_NEUCR/117-221      AC Q7S057.2
#=GS F2SW09_TRIRC/134-237      AC F2SW09.1
#=GS R1GKW3_BOTPV/121-226      AC R1GKW3.1
#=GS M2S127_COCSN/143-247      AC M2S127.1
#=GS C3KH67_ANOFI/130-229      AC C3KH67.1
#=GS G4U9C1_NEUT9/134-238      AC G4U9C1.1
#=GS C7YHL1_NECH7/124-204      AC C7YHL1.1
#=GS E6ZMG3_SPORE/187-295      AC E6ZMG3.1
#=GS H0Y9E6_HUMAN/79-179       AC H0Y9E6.1
#=GS F7HY65_CALJA/139-240      AC F7HY65.1
#=GS W3XLN9_9PEZI/113-217      AC W3XLN9.1
#=GS D4DK94_TRIVH/134-237      AC D4DK94.1
#=GS CENPH_CHICK/125-224       AC Q90ZF9.1
#=GS G5B8V0_HETGA/134-234      AC G5B8V0.1
#=GS F2UDY6_SALR5/146-245      AC F2UDY6.1
#=GS A0A022X7A2_TRIRU/134-237  AC A0A022X7A2.1
#=GS E9CYZ8_COCPS/136-238      AC E9CYZ8.1
#=GS I3LPJ0_PIG/136-236        AC I3LPJ0.1
#=GS W9CFS5_9HELO/129-233      AC W9CFS5.1
#=GS A0A023AN74_TRIRU/134-237  AC A0A023AN74.1
#=GS G4MS99_MAGO7/128-234      AC G4MS99.1
#=GS W9Q501_FUSOX/124-227      AC W9Q501.1
#=GS A0A022ZU96_TRIRU/134-237  AC A0A022ZU96.1
#=GS W4YCN7_STRPU/261-305      AC W4YCN7.1
#=GS C1GTZ3_PARBA/79-182       AC C1GTZ3.1
#=GS H1V387_COLHI/124-228      AC H1V387.1
#=GS M7P2Q2_PNEMU/141-244      AC M7P2Q2.1
#=GS L8IWN4_9CETA/136-236      AC L8IWN4.1
#=GS C5FS81_ARTOC/126-229      AC C5FS81.1
#=GS U6CPQ7_NEOVI/139-239      AC U6CPQ7.1
#=GS S8AUN6_PENO1/132-235      AC S8AUN6.1
#=GS T5AIQ5_OPHSC/121-225      AC T5AIQ5.1
M9MD73_PSEA3/184-303                 ................................................................afl---KTFN.ETRAIKDERIAVKAEIREQR...LKTLR..LLESI..KAIKAEIKAEIrtrqlnpagsgaandsDASQDMA.AVRKVQ.QMQREINEARSKKELVKGILR.GLILES.GRDWTK...NKATRTLML-s.......
W3VR34_9BASI/184-299                 ................................................................afl---KTFN.ETRAIKEERIAVKAEIREQR...LKTLR..LLESI..KAIKAEIRTRQlnpags....gaandsDASQDMA.AVRRVQ.QMQREINEARSKKELVKGILR.GLILES.GRDWTK...NKATRTLML-s.......
A6DTA5_9BACT/51-160                  .................................................................ai--VRTLN.QYGQTEEQVKIIESHIEALD...KREKE..IVAQI..VALSNTINKAIeasd........indpSTLEDQS.YTTPLE.KLNRNVKNLYDRANTLSETFK.QAIAAApLVDWTA...D---------gdqlas..
X0BXV4_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
F0ZEI0_DICPU/174-272                 ......................................................lskirdegveicl---KLIS.QIELNNDEILKIRKKRIEEM...KLNRE..TYNNL..-----------................-KMKLEE.SKSKTE.REQKNYSVLKDKTSLLGFIIQ.NLVYES.GIDWVK...DDEIT-----yf......
G3QGP4_GORGO/139-239                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
D8M956_BLAHO/143-243                 ..................................................................e-YERKLQ.ENASLLEENQSLKAACDTLRgqiHEQET..VLQEM..------EEKES................KSVNREK.QQHELK.IAISKYEVQRRQNEILRNIYS.SLVLAS.RIDWAR...KDRIREMML-c.......
F2TJI4_AJEDA/140-243                 ..................................................................i-YTNLSR.AHASCTQSLSTAKVDSIHST...AKNQK..LVQTL..LGLTSAQTSWR................EGITDQK.LRSQLE.TLEKETKAEKANWVTIKRIVS.AAIVAS.GVDWAA...DEQLHDLVVD........
W6MKX9_9ASCO/125-232                 .............................................................qlaqdv--LMLEK.EIDSVGSDANAVRKLNKDTI...ESEKV..KLADL..LDLLGKNMDSN................MKLKNSQ.MSSELA.DIEEQITASSEKVRVLAGVTL.GVITSS.GLNWGK...DAHSQKIVLD........
H2QR06_PANTR/139-239                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTKKNKQK................IDLDSME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
C5P9N1_COCP7/136-238                 ..................................................................v-YENLAG.VNNSCVENLSNAEVSNIRAV...KDNRD..LVRSL..LELTDGNA-EE................EEIKDLK.SKEELE.TLKRENKNRRDEYMTMKRIVS.AVIVAS.GLDWAS...DEKLLTLVV-e.......
F7GDG6_ORNAN/107-207                 ..................................................................a-ILKAQQ.ETRELDGRLLEVRKKRLALK...QTGEG..KLVDI..---QTLKRKKK................EELEGME.ASDLLK.RIKENVRKEIQMTVVIQNVFQ.NIIIGT.QVNWAE...DPALKNIVLQ........
G0RDU4_HYPJQ/125-229                 ..................................................................s-VAKHAD.SMAKLRRDLASVQVQSIRVC...RENVK..LTAQV..FELAEQAKQRK...............aVRLDDPD.VQREMD.KLTREVKASRQRWKVMKGVAS.GIVAGS.GVDWAA...DEELRNIVLD........
A2QDK2_ASPNC/77-180                  ..................................................................a-HENLNT.AHNATLRRLSSLEVENSQIH...QQNQE..LVREL..LALTVDDESWR................ENLEDAE.LKAQLD.QLDADRRKSKAKWETMKNIAS.GMVVGS.GVNWAE...DERLTALVLD........
C1BYA2_ESOLU/129-228                 ..................................................................k-IKTLQQ.ESFELQDQITALQKQRLDLK...RLTHE..KMKEM..----EELKTKG................EHPVAEE.YRNVLQ.KAQSYLEKYQKMVAIEQNVLR.GIIIAS.KVNWRE...DPKLREIAM-t.......
C6HRL4_AJECH/140-243                 ..................................................................i-YVNLSR.AHGSCTQSLSNTKVDGMHGT...AKTQE..LVQTL..LGLTSAEKSRR................EAITDPA.LISQLE.AQEKETKAERASWVTMKRVVS.ALIVAS.GIDWAA...DEALHDLVVD........
E9E019_METAQ/126-230                 ..................................................................n-VAKHAT.EVAFIRNDLTQVQSDTARVI...RRNVG..LTSTL..FELAEEVKQKQ...............aSRLDDEE.TQSEIR.QLEVAMMASRQRWRVIKGVAS.GIVAGS.GVDWAR...DAKLREVVLD........
G3J8R7_CORMM/143-240                 .................................................................da--ARSAT.QAQATRDALTDVQVETLRAC...RRNVQ..LTSRV..FELAAQLEARK................AVDWDGG.------.EEALRVRDEKRKWRAVKGAAS.GIVAGS.GVDWAS...DEALRDMVLD........
S3CBC6_OPHP1/206-307                 ..................................................................a-VAREAA.ARHAADDERAAAAAACRQIE...TKNVE..LAADA..--GADGSGSGS................GGHAPDD.EPSELS.QLRASVKASRQRWKLIKGAAS.AIVVGS.GVDWAR...DAALLEIVLD........
H0VRH0_CAVPO/1-95                    ...................................................................------Q.ESWELEEKLLDIRKKRLQLK...HASEN..KLLEI..---QTEKKKRK................EELNSMG.NSDKIK.TMQQILQTEMEIATVIQHVFQ.NIILGS.KVNWAA...DPALKETVLQ........
A8WHV8_DANRE/129-227                 .................................................................kt--IQILK.ETRELQDQITDVQKQRLDLK...GQIKK..KMQEI..NELKQEK----................-ENQGEV.QQKTKE.RAEAVLQKYQRITTILQNVLR.GIILAS.KVNWRE...DPKLSDIVMK........
X0LPP1_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
U4LJT9_PYROM/163-262                 ..................................................................t-HAHLSS.LLLHRQTSLTSLQTSTISLS...LRNKE..LAAQI..LELSQQREKEK................----EIH.KTGEYK.KAEEAYKAAKRKWDVTSGVTR.AIVVES.GVDWAR...DEGLRVVVV-g.......
V5FDE0_BYSSN/134-237                 ..................................................................v-YENLAA.THTEILDALSNAEVENRQIT...EKNQR..LVRRL..FELTDQESSWK................EEITDPK.LKAQLQ.DLEADQKKSRARWETVKGVAS.AAVVAS.GVDWAR...DDALRELVLD........
S3DE02_GLAL2/144-247                 ..................................................................t-LADLSR.KVLNAKKELIKVETENVNTN...RQNAE..LAAQM..ISLAKDADTQK................RDNMSRK.AQKDLA.EMDQKVKSIRQTWRIMKGTAS.GTIVGS.GVDWAR...DPELLEIVLD........
K1S4I7_CRAGI/459-554                 ..................................................................d-IMRTLK.DCTKYQEELDHVKKENRDIL...VENRQ..LLKEL..--------REK................QENTKKI.NDQETQ.SLCEELDQQLRMISITRAILQ.GLIVGS.GVHWAE...NQQLQELVLK........
C1C429_LITCT/155-253                 ..................................................................q-ILSVQL.SNRQFQQQLTGIRKRRMEIR...IQQQD..LFGKL..----RYSGKTN................HKIHDIE.-MKAFA.TERKHLESLLSEVVILQEVFQ.RLLMSV.QLHWAE...KLHLRSLLL-r.......
G1QVE6_NOMLE/139-239                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDGME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
N4TPR3_FUSC1/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
A0A016PXT1_GIBZA/124-228             ..................................................................s-VARQAS.QTNEVWKALTTAQSDTLRKS...RENVT..LAAEL..FELADQAKLKK...............rVPPNNSK.MMEEQK.RLEAEVKASKQKWRVMKGVAG.GIIVGS.GVDWVQ...DDELRDVVLD........
L0PG58_PNEJ8/139-231                 ................................................ncdniiskllkfhnfllkn-------.-------------------E...KKILH..LQKET..LKLFSENRKKD................----REE.KMLSVL.EKQQKDKLVREMNDIKHRVII.GIILES.GIDWYG...NEHWRNMMLK........
M1EJ07_MUSPF/121-213                 ..................................................................l-IMKSHQ.ESWDLEEKLLDVRKKRLQLK...QASES..KLLEI..---QTEKNKQK................DDLAVME.NSDKIK.AIQQNLQMEIQITTVIQHVFQ.NLILGS.KANWAE...DP--------........
M7U4T3_BOTF1/129-233                 ..................................................................t-LAQISN.QIQSSREELMRESNENIVTG...RKNIE..LATEM..LALAEEANSQG...............kENIQDPD.VRAQLD.ELEGAMKNSRQRWRIMKNTAS.AVIVGS.GIDWAR...DPKLLALVLD........
S9X945_SCHCR/106-212                 ...............................................................yves----LLQ.KQNFFCEENLSVEEEIFDLH...KKIQEerGILQV..LEPATQEVAASl..............lQHSSKSGvYRDFME.STQQELRTEKVRWEVLRNVVQ.VLILES.GLSFAD...DEQLFYIM--........
G7XPL2_ASPKW/132-235                 ..................................................................a-HENLNT.AHSATLRRLASLEVENSQIH...RQNQE..LVREL..LALTEDDESWR................ENLEDAE.LKAQLD.QLDADRRKSKAKWETMKNIAS.GMVVGS.GVNWAE...DERLTALVLD........
K9GST4_PEND1/188-291                 ..................................................................a-HENLAS.AHDLVMRQLSNLEVKNLQIN...RQNQE..LVRQL..LELTKEDSSWK................EKLEDPE.LLSQLD.SFETDLKARKTQWETLKSIAS.AVVVAS.GLNWAD...DDTLRALVLD........
Q4P7V5_USTMA/178-295                 ...........................................................qaleflrv-----FN.QIRSIKKQRIEVKARIREQR...LETMK..LLENI..KAIKADIRSRQlrpaa.....sgtqtsGASPDIV.VVQKVQ.QMQREINEARSKKELVKGILR.GLIIES.GRDWTK...NASTRALML-s.......
A0A058ZAT0_9EUKA/203-321             .................................................................ac--QQHES.LIQKVQERLVSIEREVLGLQ...LAYNK..KVKFA..AELERQNFLRRlersss....aqtatrDGEQMPR.SDTGNS.QASAGLQKRLASNAILRNVLQ.LLVLES.GVDWMApeaDEEFRRTVL-s.......
W6Q3I3_PENRO/137-240                 ..................................................................a-HENLAS.AHDLVMRQLSNLQVKNLQIN...RENQE..LVRQL..LELTKEDSSWR................EKLEDPE.LLSRLD.KSETDFKARKAQWETMKSIAS.AVVVAS.GLNWAD...DDMLRALVLD........
E3QDF7_COLGM/124-228                 ................................................................tls---ETSS.DIRAAINELTEVEAESLRVG...RRNVE..LTAEI..LRLTEEAEARR...............mGETGDFG.VQGDMY.RLQAEVKASRQRWKVMKGTAS.AIVVGS.GIDWTR...DEALTDIVLD........
V5EX88_PSEBG/186-302                 .............................................................qalefl---KVFN.EIRTIKNQRVQVKKRIREQR...LETMK..LLENI..KGVKADIRNRQlhpag......gqqdpDASQDLA.IVQRVQ.QMQREINEARSKKELVKGILR.GLILES.GRDWTK...NPSTRALML-s.......
A0A022WAH9_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
G2R207_THITE/121-225                 .............................................................kvaslc------A.DLDSAWGRLAELETESLRAT...QRNME..LASEV..LRLAAGTNDKT...............pSQLEGGR.LEMELA.GHEAEMKSNRRRWRIMKGAAS.AIVAGS.GIDWVR...DERLRDLVLD........
Q0CNP0_ASPTN/132-235                 ..................................................................a-HENLNA.AQNSTLRKLSDVEVENLQLH...RKNKD..LVQEL..LSLTKNDESWR................EKLEDAD.LRAQLD.QVRTDYKKSKAKWDTMKSVAS.AIVVGS.GVNWAE...DEDLLSLVLD........
F2S7D6_TRIT1/134-237                 ..................................................................a-YENMLT.THTTCLRKLSNAEVSNIQSI...KQNQE..LVQSL..LKLTSREKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASIAAS.GVDWAS...DEKLERLVLD........
N4VG30_COLOR/126-230                 ..................................................................t-ISKTAS.EIRKTVDSLTEIEAESLRVG...RRNVE..LTAEI..LQLAEEAEKRK...............aGETDDPA.VQMETA.RLRGGLKASRQRWKVMKGTAS.AVVAGS.GVDWAR...DESLRDIVLD........
F7HY66_CALJA/139-239                 ..................................................................l-VMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDGME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKETVLQ........
J4UP66_BEAB2/149-246                 ..................................................................q-VAQGAA.QAQDTRDSLTDVQAETLRAC...RRNVN..LTSKL..FELAAQLKERK................AVDWDGG.------.EEALRVRDEKRKWRTVKGAAS.GIVAGS.GVDWAS...DEALRDMVLD........
F8MZG8_NEUT8/99-203                  ..................................................................e-AAEQAS.ASYQVRDHILDLELERLRVG...QHNAT..LASEL..LRLSKTTGTHN................VQVDGSTkLGRKLG.KTKGELRVSRQKWKTIKGATS.ALVAGT.GVDWAR...DERLRDLVLD........
S8AGL4_DACHA/151-250                 ..................................................................t-LLQLTS.QLSTLQQMYTQSSTALIKHT...NTNRE..LAERV..RQLSAANE---................-FTESIT.GNERVV.AKKAEMMKEQRRCQTLKGVVQ.GIIVGS.GVNWAE...DETLRRLVLE........
M3ZY84_XIPMA/128-227                 ..................................................................q-IKRLQM.ETRNLQDEITEIQKERLEIK...RLTHE..KMKET..----QELLSNK................EQPDSEK.YKALLE.KGQVNVETYKKMIIMAQNVLR.GILLAC.KVNWLD...EPNLREIVM-t.......
S7MFI6_MYOBR/572-652                 ..................................................................i-IMKLQQ.ESWDLEEKLLDVKKKRFELK...RASES..KFLEI..---QTEKNKQK................DALASME.NSDKIK.TLQQKLQKEIQITTVIQHVFQ.V-----.------...----------v.......
G1X4K7_ARTOA/150-249                 ..................................................................t-LIHLTS.QLSTLQEAHNRSSAKLTSLT...KSNKS..LAEQL..KQLSLE----H................EISENIT.TNEKLI.AAKEETMKAQRQCRTLKGVLQ.GIIAGS.GVDWAE...DDVLRELVLE........
W9L3C0_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQKWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
E3RR68_PYRTT/165-266                 ................................................................let------S.KLAGVRRALSVAEQGNILAK...QKNRE..LAQTM..VALAEEMKKQS...............aQDIEDAQ.LRQRVE.GVEKEVKESRRRVRTVRGMLS.AMVVGS.GINWAA...DEALTELVMD........
I3K852_ORENI/132-230                 ..................................................................h-IKHLQQ.ESKKLQDEITEIQKNRLEMK...RVTHE..KIKHM..-----EEFSKK................EYPDMEK.YKAALE.KGQANLEKYKKMAIMTQNVLR.GILLAC.KVNWLD...DPKLRDIAM-t.......
G3W0S9_SARHA/100-200                 ..................................................................s-ILKAQQ.LTRDLEEKMLEVKKKRLMFK...KAGEE..KVLEI..---KAEKKRKK................DESSLLN.NSPLII.KMKKNLQKEIDTTVIIQNVFQ.HIVMAA.KIDWAA...DPDLKALILQ........
G7P7N4_MACFA/139-239                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSDRIK.IIRQNLQMEIKITTIIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
X0FGU5_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQKWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
J9P5K5_CANFA/142-229                 ..................................................................l-IMKSHQ.ESWDLEEKLLDVRKKRLELK...QSSEN..KLLEI..---QTEKNKQK................DDLANME.NSNKIK.AMQRNLKMEIQITTVIQNVFQ.NLILGS.KA----...----------n.......
L5KLI2_PTEAL/136-236                 ..................................................................l-IMKSQQ.ESWDLEKKLLDVRKKRFELK...QASES..KLLEI..---QTEKNKQK................DDLDCME.KSGEIK.TIQQNLQMEIQITTVIQHVFQ.NLILGS.KVNWAE...DSAFKETVLQ........
C3YVM5_BRAFL/132-231                 .................................................................el--GKYHK.DIQDLQENLDRVKKDSFEQQ...VRNRE..LMTQV..----QQRKEGQ................QQRSQDD.SSDRVK.MFESHLEQAMSKISSLQHIFQ.ALMIGS.QVHWAD...DPDMEQLMI-s.......
W7LER0_GIBM7/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKT...RENVT..LAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
E9C9D8_CAPO3/160-267                 ..................................................................e-ALAWSQ.SVAAKHALLHKLEQEAKVLR...TANRE..LSATV..RAHRQELDAMSa.............paALGPARHsAANKLH.EARINFGLQRSRSRMVRNVFQ.ALVLES.GVNWMD...DPAFASLVL-s.......
W6YNJ3_COCCA/129-233                 ................................................................thg---AQTA.KLASTTRALSAAEQGNMVAN...QKNRE..LAQTM..LALAEEMKAQS...............vQDIEDAQ.LRSQVD.AVEKQLVESRRRVKTLKGVLS.GMIVGS.GINWAA...DEGLTELVMD........
Q4RUR4_TETNG/34-133                  ..................................................................h-IKQLQQ.ESRELQDEIIDIQKRRLEMK...RLTHE..KIKEM..----EELMAKK................EPPDSQK.YKAALE.KGQSNLEKYKKMAVMTQNVLR.GIILAC.KINWMD...DPKLRDIAM-s.......
A0A022YWV2_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
CENPH_MOUSE/133-233                  ..................................................................l-IMKSQE.ESSELEKKLLDVRKKRLQLK...QASRS..KLLEI..---QIEKNKQK................EDVDKME.NSEMIK.TMKKKLQTEIKITTVVQHTFQ.GLILAS.KTNWAE...DPALRETVLQ........
A0A059K9Y5_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
F7IJ38_CALJA/120-220                 ..................................................................l-VMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDGME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKETVLQ........
G1PLH1_MYOLU/97-197                  ..................................................................i-IMKLQQ.ESWDLEEKLLDVKKKRFELK...RASES..KFLEI..---QTEKNKEK................DALASME.NSDKIK.TLQQKLQKEIQITTVIQHVFQ.NLILGS.KVNWAE...DSAFKETVLQ........
G1KSK7_ANOCA/129-229                 ..................................................................a-ILQSEQ.QSRELEEKLNEVKRSRIALK...RAGEC..KLAQI..---RDIKRKRK................AELENMK.VGEILE.KVHGDLQKKIKITTIVQNVFQ.NIIFAS.KVNWEE...DSDLKAIVLQ........
A0A022VGW1_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
G3Y3L7_ASPNA/134-237                 ..................................................................a-HENLNT.AHNATLRRLSSLEVENSQIH...QQNQE..LVREL..LALTVDDESWR................ENLEDAE.LKAQLD.QLDADRRKSKAKWETMKNIAS.GMVVGS.GVNWAE...DERLTALVLD........
C5JUC6_AJEDS/140-243                 ..................................................................i-YTNLSR.AHASCTQSLSTAKVDSIHST...AKNQK..LVQTL..LGLTSAQTSWR................EGITDQK.LRSQLE.TLEKETKAEKANWVTIKRIVS.AAIVAS.GVDWAA...DEQLHDLVVD........
E2R8X4_CANFA/135-234                 ..................................................................l-IMKSHQ.ESWDLEEKLLDVRKKRLELK...QSSEN..KLLEI..---QTEKNKQK................DDLANME.NSNKIK.AMQRNLKMEIQITTVIQNVFQ.NLILGS.K-QWAE...DPTLKEIVL-r.......
M3X519_FELCA/137-237                 ..................................................................l-IMKLQQ.ESWDLEEKLLDVRKKRLQLK...QASES..KLLEI..---QTEKNKQK................DDLAIME.NSDKIK.TVQQNLQTEIQVTTVIQHVFQ.NLILGS.KANWAE...DSAFKEIVLQ........
A0A028JWP4_TRIRU/134-237             ..................................................................a-YENMLT.THTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
E4UNM1_ARTGP/134-237                 ..................................................................a-YENILT.THTTCIRELSNAEVSNIQSI...KQNQE..LVQSL..LKLTRNEKSAD................EEIPDQE.LKEELN.SLISENKQKKAQWTRMKRIVS.ASIAAS.GVDWAS...DEKLERLVLD........
W5ML56_LEPOC/132-231                 ..................................................................r-IEKMKQ.ESRETEEQLLEIQKKRLELK...KLNNG..KMKEI..----QELKMMC................DHPERGK.YSEILK.QGQKNLDKYLQMVAVVKNVFQ.GIIIAS.KVNWAA...DSKLKDVIL-g.......
N1R9G4_FUSC4/124-227                 ..................................................................s-VATQAA.ETNKVISVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
H0ZVC1_TAEGU/75-174                  ..................................................................t-IIDYQK.KIHEKEQQLINIRRERLSLK...VYGGQ..KLQQI..---QTMMKRQK................EKQASMD.-VRKIE.KMLANLEKEREMTTIIQNVFQ.NIIVGS.KVNWAE...DPSLKAIVLQ........
M0R9L1_RAT/78-178                    ..................................................................l-IMKSQE.ESKELEKKLLDVRKKRLQLK...QASRS..KLLEI..---QTERNKQK................EDVDKME.NSEVVK.AMKDKLQLEIKITTVIQHAFQ.GLILGS.KTNWAE...DPTLRELVLQ........
W5P6W1_SHEEP/136-236                 ..................................................................l-IMKSQQ.ETWDLEEKLLDVRKKRLQLK...QASER..KLSEI..---QTEKNKQK................DDLDSME.NSDKIK.TIQQKLETEIQITTVIQHVFQ.NLILGS.KVNWAE...DPALKETVLQ........
G1L8V0_AILME/138-239                 ..................................................................l-IMKSHQ.ESWDLEEKLLDVRKKRLQLK...QASES..KLLEI..---QTEKNKQK................DDLVDME.NSDKIK.TIQQNLQMEIQITTVIQHVFQqNLILGS.KANWAE...DSAFKETVLQ........
W9MBK9_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQKWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
N4XEX5_COCH4/146-250                 ...............................................................thga----QTG.RLASTTRALSAAEQGNMVAN...QKNRE..LAQTM..LALAEEMKAQS...............vQDIEDAQ.LRSQVD.AAEKQLAESRRRVKTLKGVLS.GMIVGS.GINWAA...DEGLTELVMD........
N1JMQ1_BLUG1/154-259                 ..................................................................c-LTKLAK.KEEKMLAELLEKEADNIRIA...RENTN..LAATM..LELAEKRRYPQh..............rSTSEDNT.VQKEIF.AMENKLQASRRKWKMMKETAS.AAVAGS.GVAWAR...DPELLLLVLD........
F2PHW1_TRIEC/134-237                 ..................................................................a-YENMLT.THTTCLRKLSNAEVSNIQSI...KQNQE..LVQSL..LKLTSREKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASIAAS.GVDWAS...DEKLERLVLD........
B9EMR0_SALSA/132-231                 ..................................................................k-IKTLQQ.ESCELQDQITDLKKQRLDLK...RLTHE..KMKEM..----DELKRKR................EHPEAEK.YRNVLQ.KGQSHLEKYQKMATITQNVLR.GIIIAS.KVNWRD...DPKLRDIAM-t.......
A0A024SLG9_HYPJE/119-223             ..................................................................s-VAKHAD.SMAKLRRDLASVQVQSIRVC...RENVK..LTAQV..FELAEQAKQRK...............aVRLDDPD.VQREMD.KLTREVKASRQRWKVMKGVAS.GIVAGS.GVDWAA...DEELRNIVLD........
Q0UIN8_PHANO/134-237                 ................................................................hgs----LTS.KLVSTQRTINTAAQANIVAS...RKNRE..LAAEM..LALAEDMKAQS...............aKDIEDPR.LRDQVS.AVEKELRESRRRAKTLKGVLS.AMVVGS.GINWAA...DEGLTELVMD........
I2FUH6_USTH4/185-304                 ............................................................dqalefl---KIFN.EIREVKKERVTVKARIREQR...LETLK..LLETI..KGIKADIRNRQlhpssg....grqqdsDGSQDIA.IVQKVQ.QMQREINEARSKKELVKGILR.GLILES.GRDWTK...STATRGLML-s.......
F7BNS0_XENTR/139-237                 ..................................................................m-IQAVQS.SNRILEEKLASVRKSRMEVR...LLQQE..LFKKV..----KITEERK................NKLQEIE.MKTQVV.G-KENMDTVANKVIIIQEIFQ.RCILST.HTDWSE...DPHLTRLLL-k.......
E5A8D5_LEPMJ/54-157                  .................................................................hg---AQTT.KLASVTRALSTAEQANMIAN...RKNRE..LAQRM..LALAEDMKAQS...............vKDIEDPQ.LRAQVD.AVEKALKESRRRKKTVKGILS.AMIVGS.GIHWAA...DAELTELVMD........
J9MCS4_FUSO4/124-227                 ..................................................................s-VATQAA.ATNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
A0A017SCB4_9EURO/133-236             ..................................................................a-HENLHT.AHNATLRRLSNLEVENRQIH...DKNRE..LVRQL..LELSGPDGSWR................DQLEDRD.LRAQLD.ALDAEQQKCQARWEVMKNVAS.AVVVGS.GVNWAD...DGKLSALVLD........
A1D6R3_NEOFI/132-235                 ..................................................................t-HENLMN.AHNATLRELSNVEVQNLQLH...QKNQE..LARQL..LESTKDDDSWR................EALDDDD.LKAQLE.QLEADRKRSKSRWEVMKSVAS.AIVVGS.GVNWAE...DDELTALVID........
G9NA91_HYPVG/115-218                 ..................................................................s-VAKQAE.STTKLRRDLTKVQVQSIRIC...RENVK..LTEQL..FELAEQAKQKA................IRLNNPE.VQREMD.KLTREVKYSRQRWKVMKGVAS.GIIAGS.GVDWAG...DEDLRNIVLD........
U7Q6J0_SPOS1/114-225                 ..................................................................a-VAQESS.ARREAHDESATVAAELRQLE...KQNAR..LAAEV..RELALAIAATDqpgp........atagDEGDMDE.VVLEQK.KLLSGVKTSRQRWTLIKGTAS.AIIVGS.GVDWTK...EVALSDIVLD........
X0IDI1_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
R8BT39_TOGMI/119-223                 ..................................................................s-VAQLST.ELRGVLDRITEVESESLRVS...RKNVE..LASEV..LRLAEEANREK...............eDAIEDQH.AKAEIE.RLERELKVSRQRWKVMKGTAS.AVIAGS.GVDWAS...DAELREMVLD........
B3KVZ3_HUMAN/120-220                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
Q2UKQ1_ASPOR/160-263                 ..................................................................a-HENLNT.ALSSTLKKLSNAEVENLQLH...QKNKA..LVREL..LDLTKNDESWR................EELDDMS.IKELLE.QVKADHKRSKAKWETMKSITS.AIVVGS.GVNWAE...DEELVALVLD........
L5LYK0_MYODS/463-563                 ..................................................................i-IMKLQQ.ESWDLEEKLLNVKKKRFELK...RASES..KFLEI..---QTEKNKEK................DALTSME.NSDKIK.TLQQKLQKEIQITTVIQHVFQ.NLILGS.KVNWAE...DSAFKETVLQ........
B6Q331_PENMQ/136-239                 ..................................................................v-YENLVN.ARTTTVEALSNAEVENLRLM...EQNKG..LASEL..LELTAQETLWR................DRIDDEA.VIAQME.DIEQEYKKTRARRDTIKSVIS.ALVVGS.GVDWAR...DDRLRSLVLD........
J3P818_GAGT3/123-230                 ..................................................................a-VATQST.ELHEVLDRLTRVESESAAAS...RRNVE..LAAEM..LRLAGEAARDDkm............plPDGDDDG.DGGRIA.RLEDELRQSRRRLRVMKGTAS.AVVVGS.GVDWVR...DPALRDMVLD........
F7GYV6_MACMU/139-239                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSDRIK.IIRQNLQMEIKITTIIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
B0XXC4_ASPFC/132-235                 ..................................................................a-HENLMN.AHNATLRELSNLEVQNLELH...QRNQE..LARQL..LESAKDDDSWR................EALDDDD.LKAQLE.QLEADRKKSKSRWEVMKSVAS.AIVVGS.GVNWAE...DDELTALVID........
G9P907_HYPAI/119-223                 ..................................................................s-VAQHAD.SVAKLRDDLTAVQVQSIRVC...RQNMD..LTSEL..FALAEQAKQKK...............aVRVDDPR.VQQEIE.KLTREVKTSRQRWRVMKGVAS.GVVAGS.GVDWAK...DEDLRNIVLD........
G2WZ89_VERDV/122-233                 ..................................................................t-LARNAT.SLRDTLDALAATRAKALSAG...RRNAE..LAQEV..LRLAEEAARRRgggs........gpkgSGGEDDE.TRRETQ.LLRAGLKASRQKWKVMKGTAS.AIVVGS.GVDWVG...DEGLRWMVLD........
B2WEL0_PYRTR/133-234                 ................................................................let------S.KLAAVTRTLSVAEQGNIAAK...QKNRE..LAQTM..LALAEEMKKQS...............aQDIQDAQ.LRQRVD.AVEKEVKESRRRVSTLKGILS.AMVVGS.GINWAA...DEALTELVMD........
L8H183_ACACA/175-303                 ssflelhaellqvereleearraraaeeeatrrlwrqakpatrgrddddddgdqgkqqrrreedddg-------.--------------------...-----..-----..----------Ddr...........meeGEETRMV.GRATGR.RAVAALQEAEAENARLREVWQ.ALILES.GLNWAA...DEQLRDV---lfr.....
C5G7F8_AJEDR/140-243                 ..................................................................i-YTNLSR.AHASCTQSLSTAKVDSLHST...AKNQK..LVQTL..LGLTSAQTSWR................EGITDQK.LRSQLE.TLEKETKAEKANWVTIKRIVS.AAIVAS.GVDWAA...DEQLHDLVVD........
L2G9P6_COLGN/126-230                 ..................................................................a-LAQTSN.EIRTTLDKLTDVEAESLRVG...RRNVE..LTAEV..LRLAEEAERRK...............aGETDDPA.VQAQMA.SLQAELKASRQRWKVMKGTAS.AVVAGS.GVDWAR...DEELREMVLD........
C4JZ24_UNCRE/135-237                 ..................................................................a-YENLAS.INSSCSERLSNAEVDNIQTA...TENRD..LVQSL..LELTRG-KDEK................LQIEDPD.LRSELE.TLERKTKKAKADYVTMKRIIS.ASIVAS.GIDWAS...DETLLKLVVD........
A0A022UD38_9EURO/134-237             ..................................................................a-YENMLT.THTTCLRKLSNAEVSNIQSI...KQNQE..LVQSL..LKLTSSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASIAAS.GVDWAS...DENLERLVLD........
B6H4J5_PENCW/132-235                 ..................................................................a-HENLAS.AHDLVLRQLSNLEVKNLQIN...RENQE..LVRQL..LELTKEDSSWR................EKLEDHE.LLSQLD.SLETDLKARKAQWETMKSIAS.AVVVAS.GLNWAD...DDMLRALVLD........
F1M389_RAT/132-232                   ..................................................................l-IMKSQE.ESKELEKKLLDVRKKRLQLK...QASRS..KLLEI..---QTERNKQK................EDVDKME.NSEVVK.AMKDKLQLEIKITTVIQHAFQ.GLILGS.KTNWAE...DPTLRELVLQ........
A7RSC2_NEMVE/138-238                 ...................................................................EILRQHQ.AMLETQQELDQVKQQSLAMK...KRNRE..LMAKL..KDLQ----RRQ................SQGEHNSsEVEAIA.KAKDGLNDSKRKLRVVGNIFQ.GLIVGS.GINWAA...DDSLRQLMI-e.......
A1CKR0_ASPCL/132-235                 ..................................................................a-YENLTT.ADNATLRELSNVEVQNLQLN...QRNQE..LVGQL..LDMTKDDMSWR................EDLQDED.LRAQLE.ELESERRKSRARWETMKSIAS.AIVVGS.GVNWAE...DDSLTALVLD........
Q5B994_EMENI/131-234                 ..................................................................a-LENFTE.AQASTLKKLSSLEVENLQLH...RQNQE..LVREL..LELTEDDESWR................EQLDDPE.LKQQLE.QLEAEHKQSKAKWETMKSVAS.AIIVGS.GVDWAE...DEDLTALVLD........
J3KC56_COCIM/136-238                 ..................................................................v-YENLAG.VNNSCVENLSNAEVSNIQAV...KDNRD..LVRSL..LELTDGNA-EE................EEIKDLK.SKEELE.TLKRENKNRRDEYMTMKRIVS.AVIVAS.GLDWAS...DEKLLTLVV-e.......
W7EKX9_COCVI/129-233                 ................................................................thg---AQTA.KLASTTRALSAAEQGNMAAN...QKNRE..LAQTM..LALAEEMKAQS...............vQDIEDAQ.LRSQVD.AVEKQLVESRRRVKTLKGVLS.GMIVGS.GINWAA...DEGLTELVMD........
I8IF92_ASPO3/132-235                 ..................................................................a-HENLNT.ALSSTLKKLSNAEVENLQLH...QKNKA..LVREL..LDLTKNDESWR................EELDDMS.IKELLE.QVKADHKRSKAKWETMKSITS.AIVVGS.GVNWAE...DEELVALVLD........
G2YBK7_BOTF4/129-233                 ..................................................................t-LAQISN.QIQSSREELMRESNENIVTG...RKNIE..LATEM..LALAEEANSQG...............kENIQDPD.VRAQLD.ELEGAMKNSRQRWRIMKNTAS.AVIVGS.GIDWAR...DPKLLAIVLD........
T5C4Z3_AJEDE/140-243                 ..................................................................i-YTNLSR.AHASCTQSLSTAKVDSIHST...AKNQK..LVQTL..LGLTSAQTSWR................EGITDQK.LRSQLE.TLEKETKAEKANWVTIKRIVS.AAIVAS.GVDWAA...DEQLHDLVVD........
R0JZC6_SETT2/151-255                 ................................................................mhg---AQTA.KLASTMRALSAAEQANMVAN...RQNRE..LAQTM..VALAEEMKAQS...............aQDIQDPQ.LRAQVD.AVDQQLRASRRRAKTLQGVLA.GMIVGS.GINWAA...DEGLSELVME........
L7HQQ2_MAGOY/154-260                 ..................................................................a-VANQTT.ALHETLDKLTSVEADSLALS...RKNVE..LAAEM..LDLVQEHEARRk.............gvTADEDPD.TAAEIR.RLEGQVQASRRRWRIMKGTAG.AVVVGS.GVDWVG...DPVLRDVVLD........
A0A022Y2Q2_TRISD/134-237             ..................................................................a-YENMLT.THTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
B7FSK2_PHATC/144-242                 ...............................................................qvcq---RQVQ.RALEKSRELEQVQQDVMTAT...EDSRR..MQTES..------RSCWE................SLVREGE.DDVVIS.NASTKESKDERQLRVLGRVLV.DLVTSS.NIDWYE...DDKLQEIMQ-r.......
C1G1C0_PARBD/79-182                  ..................................................................i-YENLSR.AHASCIQTLSDAKVENIQHN...EKNQQ..MVQTL..LGLTSAEKTWR................EEITDPK.LRAQLE.TVEKECKAEQANWVTIKRIVS.AAIVAS.GIDWAE...DEKLRDLVVD........
F6RXE0_XENTR/141-241                 ..................................................................s-VMNLQQkEFKILNKILISICIYYIVLK...EQGSA..KMLEI..-----QTMKSN................WKANREEmKNEKIK.RLHKVLKEEIDSVTVLQNVFQ.NIILAS.HVDWAK...YPQLKDIVL-r.......
F6PLT4_HORSE/138-238                 ..................................................................l-IMKSQQ.ESWDLEEKLLDVRKKRLQLK...QASES..KLLEI..---QTEKNKQK................DDLDSME.NSDKIK.TIQQNLQMEIQITTVIQHVFQ.NLILGS.KANWAE...DSAFKETVLQ........
L7J0Z2_MAGOP/128-234                 ..................................................................a-VANQTT.ALHETLDKLTSVEADSLALS...RKNVE..LAAEM..LDLVQEHEARRk.............gvTADEDPD.TAAEIR.RLEGQVQASRRRWRIMKGTAG.AVVVGS.GVDWVG...DPVLRDVVLD........
K0KLT4_WICCF/130-229                 ..................................................................d-IIALEN.EVSARQSKLNKLNQEINLKF...EKSKE..LTSKL..------IEKHK................NQISNNGiDNTKLKiQLQEKLKIAKNKSYNLSEEIQ.AFLVEN.GINWAK...DKKLRELVL-y.......
R7YUA9_CONA1/136-239                 ................................................................hnd----TTT.RLSTAAVELTKAERGNVIAN...EKNRE..LTQTL..LALAEETKSEK...............tEVVQDPK.LRSKLE.GLDAQIRASRREWRTMKGITA.AVIAGS.GVDWAR...DDALRGLVMD........
CENPH_BOVIN/136-236                  ..................................................................l-IMKSQQ.ETWDLEEKLLDVRKKRLQLK...QASER..KLLEI..---QTEKNKQK................DDLDSME.NSDKIK.AIQQNLETEIQITTVIQHVFQ.NLILGS.KVNWAE...DPALKETVLQ........
F9G357_FUSOF/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
H0WK59_OTOGA/138-238                 ..................................................................l-IMKSQQ.ESWDLEEKLVDVRKKRLELK...QASES..KLLEI..---QMEKNKQK................NELDSME.NSDKVK.TIQQNLQMEIQITTVVQHVFQ.NIILGS.KVNWAE...NSALKETVLQ........
D4B356_ARTBC/134-237                 ..................................................................a-YENMLT.THTTCLRKLSSAEVSNIQNI...KQNQE..LVQSL..LKLTSSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASIAAS.GVDWAS...DEKLERLVLD........
B2AM45_PODAN/109-213                 ...............................................................rtae----HCS.ALHSAMERLTKVEVEYLETK...QRNVE..LASET..LDLAADNVGQE...............pNNVINTQ.LKMELD.TLETQLRATRGKWRVMKGTAS.AIVAGS.GLDWVR...DERLRELVLD........
A0A022TWL2_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
T0KFT4_COLGC/126-230                 ..................................................................a-LAQTSN.EIRTTLDKLTDVEAESLRVG...RRNVE..LTAEV..LRLAEDAERRK...............aGETDDPA.VQAQMA.SLEADLKASRQRWKVMKGTAS.AVVAGS.GVDWAR...DEELREMVLD........
A7E7B6_SCLS1/124-228                 ..................................................................n-LAQVSN.NLQSSREELMKESNENIITG...RKNVE..LATEM..MVLAEEASSQG...............kENIQDPE.VRAQLD.ELEAAMKNSRQRWRIMKNTAS.AVVVGS.GVDWAR...DPKLLEIVLD........
S9PPG1_SCHOY/101-208                 .................................................................yv--ESLLQ.EQNHLSDQNLQVEEEIIELNrkiQEERI..LLQSI..-EPASQKVAGSl..............lQHSSKSEvYRDSME.SIQHELRTERCRWEILRNVVQ.VIILES.GSSFAD...DEQLLQIM--e.......
Q6CEC4_YARLI/132-229                 ...........................................................dlldsliv-------.-VTGLRKQLDVLICENRASL...DTQRS..IVRSI..-----E--KAN................DKSADRHqNNQAIS.ELEAKLHNTKNKRRVLAEIFT.ALITAS.GIDWCE...DEDLVQLIV-g.......
U3KP60_RABIT/136-236                 ..................................................................l-IIRSQK.ESRSLERKRLEIRKKRLDLK...KASES..KLLEI..---QTEKNKQK................EDLDSME.NSDKIK.TIRQNLQMEINVTTVIQHVFQ.NLILGS.KTNWAE...DSALKEIVLQ........
C9SMQ0_VERA1/30-141                  ..................................................................t-LARNAT.NLRDTLDALAATRAGALAAG...RRNAE..LAQEV..LRLAEEAARRRdggs........epqgGGGEDDE.ARREMQ.LLRAGLKASRQKWKVMKGTAS.AIVVGS.GVDWVG...DEGLRWMVLD........
A0A015K5T7_9GLOM/152-253             ..................................................................f--LKSHQ.ELLGIQYELTNLKKAVIVRH...IENRI..LMRQI..NEITSKPMTKY................YE-SSGN.NQAEIL.QLKINLTNARSKREIVRNVLQ.GLILES.GVEWAN...DEHLLKLML-v.......
M4FRL0_MAGP6/123-229                 ..................................................................e-VATQST.ELHEMLDRLTKVESESAAVS...RRNVE..LATEM..LRLAEEAARDDk.............vlLEDDDGG.DGGLLA.RLENELRQSRRRLRVMKGTAS.AVVVGS.GVDWVR...DPALRDMVLD........
C0NUZ1_AJECG/140-243                 ..................................................................i-YVNLSR.AHASCTQSLSNTKVDSMHGT...AKTQE..LVQTL..LGLTSAEKSRR................EAITDPA.LISQLE.AQEKETKAERASWVTMKRVVS.ALIVAS.GIDWAA...DEALHDLVVD........
K3V3C0_FUSPC/124-228                 ..................................................................s-VARQAS.QTNEVWKALTTAQSDTLRKS...RENVT..LAAEL..FELADQAKLKK...............rVPPNNSK.MIEEQE.RLEAEVNASKQKWRVMKGVAG.GIIVGS.GVDWVQ...DDELRDVVLD........
M1WHU5_CLAP2/130-234                 ..................................................................a-VAKHAT.DIGFIRNDLTEVQSDTARVV...RKNVV..LTSTL..FELAEEVKKKQ...............aTRLDDEE.TQSEMA.KLETAMKASRQRWRVMKGLAS.GIVAGS.GVDWAR...DGKLREVVLD........
K9F993_PEND2/188-291                 ..................................................................a-HENLAS.AHDLVMRQLSNLEVKNLQIN...RQNQE..LVRQL..LELTKEDSSWK................EKLEDPE.LLSQLD.SFETDLKARKTQWETLKSIAS.AVVVAS.GLNWAD...DDTLRALVLD........
X0LST7_FUSOX/124-227                 ..................................................................s-VATQAA.ETNKVISVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
K7FU00_PELSI/85-165                  ..................................................................a-ILESQQ.QARELEEKLNEIKKRRFALK...QAGEH..TLLQI..---HTLKKKQK................EELEGME.VGEMLK.RVCRNLQKETQMTTLIQNIFQ.V-----.------...----------v.......
W7I3G8_9PEZI/150-249                 ..................................................................t-LLHLTS.QLSNLQRTYTTAASSLIAHT...DRNKD..LAEQL..RQLSAANEFT-................---EAIT.TNEAVI.AKKAKLATEQRRCETLKGVVQ.GIIVGS.GVNWSE...DEALQRLVLE........
M7T7G4_EUTLA/30-139                  ..................................................................t-LAKQSA.EVRGLLDALTEVEGQSARVA...RENSS..LAAEV..LLLAEQSNRGRsra..........eleSAVTDSD.LVAEMA.ELEAQVRASRKKWRVVKGTAS.AIVAGS.GVDWAR...DPELRDIVLD........
G5BKN6_HETGA/100-200                 ..................................................................s-VMKLQQ.ESWELEEKLLDVRKKRFQLK...QASES..KLLEI..---QTEKKKQK................EELASME.NSDKIK.TMKQSLQREIQIATVIQHVFQ.NLILGS.KVNWAA...DPALKETVLE........
CENPH_HUMAN/139-239                  ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
M2TRP5_COCH5/129-233                 ...............................................................thga----QTG.RLASTTRALSAAEQGNMVAN...QKNRE..LAQTM..LALAEEMKAQS...............vQDIEDAQ.LRSQVD.AAEKQLAESRRRVKTLKGVLS.GMIVGS.GINWAA...DEGLTELVMD........
C3YVL8_BRAFL/23-105                  ............................................................tsatsti-------.--------------------...-SNKS..VYSET..TPTPSQDKQGV................EEEGDVT.ELVELK.GFESHLEQAMSKISSLQHIFQ.ALMIGS.QVHWAE...DPDMEQLMI-s.......
M3YT77_MUSPF/139-239                 ..................................................................l-IMKSHQ.ESWDLEEKLLDVRKKRLQLK...QASES..KLLEI..---QTEKNKQK................DDLAVME.NSDKIK.AIQQNLQMEIQITTVIQHVFQ.NLILGS.KANWAE...DPAFKETVLQ........
F0U813_AJEC8/140-243                 ..................................................................i-YVNLSR.AHGSCTQSLSNTKVDGMHGT...AKTQE..LVQTL..LGLTSAEKSRR................EAITDPA.LISQLE.AQEKETKAERASWVTMKRVVS.ALIVAS.GIDWAA...DEALHDLVVD........
A0A010RMT7_9PEZI/126-230             ..................................................................a-LANKSE.DIRSLVNQLTEVEAESLRVG...RKNVE..LTAEI..LRLTEDAEKRR...............aGETDDPA.VQAEMA.RLEAEMKASRQRWKVMKGTAS.AVVVGS.GVDWSR...DEALRDVVLD........
Q4WY32_ASPFU/132-235                 ..................................................................a-HENLMN.AHNATLRELSNLEVQNLELH...QRNQE..LARQL..LESAKDDDSWR................EALDDDD.LKAQLE.QLEADRKKSKSRWEVMKSVAS.AIVVGS.GVNWAE...DDELTALVID........
F0XUY0_GROCL/186-292                 ..................................................................a-VAQQAG.ARRAVLERHVAVAAESCRVR...RQNQA..LAEQL.hRQLAEAVEDDSa..............gGDKNNDT.HDDELT.QLQQELKASRQRWKLIKGTAS.AVVVGS.GVDWAR...DPELQNLVLD........
X0AXK5_FUSOX/124-227                 ..................................................................s-VATQAA.ATNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
I1RA59_GIBZE/124-228                 ..................................................................s-VARQAS.QTNEVWKALTTAQSDTLRKS...RENVT..LAAEL..FELADQAKLKK...............rVPPNNSK.MMEEQK.RLEAEVKASKQKWRVMKGVAG.GIIVGS.GVDWVQ...DDELRDVVLD........
K1XTB7_MARBU/123-227                 ..................................................................n-LTKLST.EARSARDELTKVEVENVMIV...RRNAE..LATTM..LALAEEADTQR...............kEDIQDPA.LRHQLD.ELEAEMKRSRQKWRIMKGTAS.AIIAGS.GVDWAR...NPDLLDIVLD........
G2Q1Y8_THIHA/112-216                 ..................................................................k-AANIYS.ELQTARARLAELEVGSLKAS...HWNRE..LAADV..LQLASENHKQD...............fESIQNGR.FGSGIA.DLESQVKSSRHRWRIIKGATS.AIIAGS.GIDWVR...VKRLRELVLD........
C1C3S7_LITCT/89-187                  .................................................................lt--LKEQK.ESRSLEKQLIDIREKRMALK...EKSTA..LMTEV..LSIVDELRFQK................E-----P.KEEKLK.KIFKHVKRETDTTFMLQNIFQ.RLIHAS.RVNWVE...DPKLREAVI-k.......
B8N1N6_ASPFN/132-235                 ..................................................................a-HENLNT.ALSSTLKKLSNAEVENLQLH...QKNKA..LVREL..LDLTKNDESWR................EELDDMS.IKELLE.QVKADHKRSKAKWETMKSITS.AIVVGS.GVNWAE...DEELVALVLD........
F7W180_SORMK/117-221                 ..................................................................k-AAQQAS.ASYEVRDRMLTLELNRIRVG...QQNAT..LASEL..LRLSKTTGATD................VEVDGATkLQRQLD.KTKGELQVSRQRWKTIKGATS.VLVAGS.GVDWVR...DERLRGLVLD........
W9IEY7_FUSOX/124-227                 ..................................................................s-VATQAA.ATNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
E9EWB2_METAR/127-231                 ..................................................................n-VAKHAT.EVAFIRNDLTEVQSDTARVI...RRNVD..LTSTL..FELAEEVKQKQ...............aSRLDDEE.TQSEIR.QLEVAMRASRQRWRVIKGVAS.GIVAGS.GVDWAR...DAKLREVVLD........
Q0P4K1_XENTR/141-240                 ..................................................................s-VMNLQQ.ETRDLEEKMYDIRKKRLVLK...EQGSA..KMLEI..-----QTMKSN................WKANREEmKNEKIK.RLHKVLKEEIDSVTVLQNVFQ.NIILAS.HVDWAK...YPQLKDIVL-r.......
L8FV22_PSED2/137-241                 ..................................................................e-LAATAA.QVLAAREALTAVEAEQVVLA...RSNTE..LAGRM..VGLAEQVEGQK...............kGDITDPE.MRGKIE.EMEREVRRSRQRWRLMKGVAS.GVVAGS.GVDWAR...DEKLRALVLD........
D2H2T8_AILME/1-56                    ..................................................................i-------.-----------------ELK...QASES..KLLEI..---QTEKNKQK................DDLVDME.NSDKIK.TIQQNLQMEIQITTVIQHVFQ.------.------...----------........
A0A059JH45_9EURO/134-237             ..................................................................a-YENMLT.THTTCLRKLSNAEVSNIQSI...KQNQE..LVQSL..LKLTSSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASIAAS.GVDWAS...DENLERLVLD........
W5KVX7_ASTMX/129-227                 ..................................................................k-TMKLVK.ETRELQDQITDIQKERLEMK...GLIKK..KMQEI..TEL----KKM-................GENQGQA.QKQAVE.RAENILQKYRKIATISQNVLR.GIILAT.KVNWIN...DPKLKDVIV-g.......
R7T969_CAPTE/150-250                 ..................................................................a-VLKIHQ.NLDSLKTELDQLQRDNLNLV...QSNRQ..LMAEL..---RREKDQQE................VETTQNK.DSPALA.RAQEKYDSSLAQLQVCRHMFQ.GLILGS.GVDWAK...DKKLRETVL-r.......
F6QC79_MONDO/99-199                  ..................................................................s-ILKAQQ.ETHDLEEKLLEVKKKRLRLK...QAGEE..KLLEI..---QAEDKKKK................EKLELLE.DSALLS.KLKKNLQREIESTTVIQNVFQ.HIIIAT.KIDWAS...DPDLKVLVLQ........
W6Z635_COCMI/143-247                 ................................................................thg---AQTA.KLASTTRALSAAEQGNMVAN...QKNRE..LAQTM..LALAEETKAQS...............vQDIEDAQ.LRSQVD.AVEKQLAESRRRVKTLRGVLS.GMIVGS.GINWAA...DEGLTELVMD........
FTA3_SCHPO/107-208                   ..........................................................etehlseen--LKIES.SITFTSEEIEKEKENIKSVL...LPSVQ..SISSS..LELYA------................--SKESD.YRSSIE.GVLADLKLARARWEIVRNVTQ.ILLLES.GISFLE...NKKLAYIM--d.......
S0DJP0_GIBF5/124-227                 ..................................................................s-VATQAA.ETNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MIQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
V9L3I7_CALMI/143-242                 ..................................................................e-IVANQK.EIRTLENKVLEVQKQRLMLK...QTMQD..VLKER..---RTEKMKQQ................QLLQEME.-NELPK.RAKKNLLEHLKTVTLIQNVLQ.GIILAS.GVNWAK...DPKLKELILQ........
A0A024JL95_GEOCN/237-335             .........................................................gngkssksdt-------.--------DLDLQAQAIQAH...ARNRT..ALSTL.dAELSAQYERI-................LARLTPA.DQAELV.ALLADLRTSRTKAAILSDLIP.MLITGS.GVDWAD...NEELSDILL-k.......
A6QRL1_AJECN/112-206                 ..............................................................iqsvh-------.-------SITDSPAESMQGT...AKTQE..SVQTL..LGLTSVEKSRR................EAITDPA.LISQLE.AQEKETKAERASWVTMKRVVS.ALIVAS.GIDWAA...DEGLHDLVVD........
H2PFR2_PONAB/139-239                 ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
C0S3I9_PARBP/143-246                 ..................................................................i-YENLSR.AHASCIQTLSDAKVENIQHN...EKNQQ..MVQTL..LGLTSAEKTWR................EEITDPK.LRAQLE.TVEKECKAEQANWVTIKRIVS.AAIVAS.GIDWAE...DEKLRDLVVD........
B8M4Y6_TALSN/136-239                 ..................................................................v-YENLAN.ARTATVEALSNAEVENLRLM...EQNKG..LASEL..LELTAQETSWR................DRVDDEA.LIARME.EIEQEYKKTRAQRDTIKSVLS.ALVVGS.GVDWAR...DDRLRDSVLE........
W4YCN7_STRPU/163-260                 ..................................................................d-ILAHLN.ACQSLQDDVDQGKKDIRDIQ...AGNVE..LMKKL..-----QSRESA................DKMNDT-.PSNSVQ.RQQEKLDDLISHITMEKGILQ.GLIIGS.GVNWAK...DPALKEVVI-g.......
R9NVN9_PSEHS/188-302                 ...............................................................eflr----VFN.EIRSIKEQRVEVKAKIRDQR...LDTMK..LLENI..KSIKADIRNRQlhpag.....satndpDASQDIA.VVQKVQ.QMQREVNEARSKKELVKGILR.GLILES.GRDWTK...SQSTRALML-s.......
B6K0U9_SCHJY/120-223                 ................................................................lls---RQAD.LTKSCLQMLHRAQEERDHGI...RLSAM..LQDTV..AECSELYKRIQ................ITSRKQEaASQSIG.DVVTQYRQVRGRWEVLRNVVQ.TLVLES.GVDWTD...NPTIMDIM--s.......
Q7S057_NEUCR/117-221                 ..................................................................e-AAEQAS.ASYQVRDHILDLELERLRVG...QHNAT..LASEL..LRLSKTTGTHD................VQVDGSTkLGRKLG.KTKGELRVSRQKWKTIKGATS.ALVAGT.GVDWAR...DERLRDLVLD........
F2SW09_TRIRC/134-237                 ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
R1GKW3_BOTPV/121-226                 .............................................................lsslia-------.NLTTTTSSLTTATKALTAAN...AKNTS..LATTL..LSLAKPPASSVa.............aaDEITDAN.LRAQLL.EAEKDATAARRRWRSVKGVAA.GVVVGS.GVDWAG...EEGLRRLVME........
M2S127_COCSN/143-247                 ................................................................thg---AQTA.KLASTTRALSAAEQGNMVAN...QKNRE..LAQTM..LALAEEMKAQS...............vQDIEDTQ.LRSQVD.AVEKQLAESRRRVKTLKGVLS.GMIVGS.GINWAA...DEGLTELVMD........
C3KH67_ANOFI/130-229                 ..................................................................q-IKQLQQ.ESRDLQDGITEVQKKRLEMK...RLTHE..KMKEM..----DELMSKT................GHPDTEK.YRAVLE.KGQANLEKYKKMTVMTQNVLR.GILLAC.KVNWLD...DPKLRDIAM-t.......
G4U9C1_NEUT9/134-238                 ................................................................eaa---EQAL.ASYQVRDHILDLELERLRVG...QHNAT..LASEL..LRLSKTTGTHD................VQVDGSTkLGRKLG.KTKGELRVSRQKWKTIKGATS.ALVAGT.GVDWAR...DERLRDLVLD........
C7YHL1_NECH7/124-204                 ..................................................................a-VAQEAA.KTGRVWDELTSTQSDTLLAS...RKNVA..STAEL..FELAEKAKQKK...............rIPPNNTK.MIQEQA.KLEAELKSSRM----------.------.------...----------fivttact
E6ZMG3_SPORE/187-295                 ...............................................netraikqqrvevkarireq-------.------------RLETMKQL...DTIKT..IKADIrtCQLHPSASARQd..............sDASQDLA.TVQKVQ.QVQREINEARSKKELVKGILR.GLILES.GRDWTK...NASTRALML-s.......
H0Y9E6_HUMAN/79-179                  ..................................................................l-IMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDSME.NSERIK.IIRQNLQMEIKITTVIQHVFQ.NLILGS.KVNWAE...DPALKEIVLQ........
F7HY65_CALJA/139-240                 ..................................................................l-VMKSQQ.ESWDLEEKLLDIRKKRLQLK...QASES..KLLEI..---QTEKNKQK................IDLDGME.NSERIK.IIRQNLQMEIKITTVIQHVFQqNLILGS.KVNWAE...DPALKETVLQ........
W3XLN9_9PEZI/113-217                 ..................................................................a-LADQTT.STKQINEEIMDVRSRTLQLS...RQNVD..LASQV..LSLAGEAEERK...............aAAVEDTE.QAEEIA.QLEQEVKASRQRWRVMKATAS.AIVAGS.GVDWAA...DEQLKSIVLD........
D4DK94_TRIVH/134-237                 ..................................................................a-YENMLS.THTTCLRKLSSAEVSNIQNI...KQNQE..LVQSL..LKLTSNDKSAD................EEIPDLE.LKEELN.RLKSENKQKKAQWTRIKRIVS.ASIAAS.GVDWAS...DEKLESLVLD........
CENPH_CHICK/125-224                  ...................................................................EIIQAHQ.QARVIRENLNDIRRKRYFLK...QAEGE..KALRI..---FTTVRKKK................-EVVRMK.IAEKLK.FIHRNVQYERKVTTLVQNILQ.NIIVGC.QINWAK...DPSLRAIILQ........
G5B8V0_HETGA/134-234                 ..............................................................nksvm-----KQ.ESWELEEKLLDVRKKRFQLK...QASES..KLLEI..---ETEKKKRK................EELGSME.NSDKIK.TMKQSLQRERQIATVIQHVFQ.NLILGS.KVNWAA...DPALKETVLE........
F2UDY6_SALR5/146-245                 ..................................................................a-CLRLSD.RYRDLTQELEMINADIRDTM...LRNRQ..IYSDI..-----QDLEQQ...............lEAGTQEP.PSQALD.NERQKLENEYVKNAILRNTLQ.LLIVAS.GVDWAA...DENLLETML-s.......
A0A022X7A2_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
E9CYZ8_COCPS/136-238                 ..................................................................v-YENLAG.VNNSCVENLSNAEVSNIRAV...KDNRD..LVRSL..LELTDGNA-EE................EEIKDLK.SKEELE.TLKRENKNRRDEYMTMKRIVS.AVIVAS.GLDWAS...DEKLLTLVV-e.......
I3LPJ0_PIG/136-236                   ..................................................................l-IMKSQQ.DTWDLEEKMLDIRKKRLQLK...QASES..KLLEI..---QMEKNKQK................DDLENME.NSEKIK.TIQRNLQREIQITTVIQHMFQ.NLILGS.KANWAE...DPALKEIVLQ........
W9CFS5_9HELO/129-233                 ..................................................................n-LAQISN.KLQSSRKEFMKESSENIITG...RKNIE..LATEM..LTLAEETNSQG...............kENIQDPG.VRAQLD.VLEGEMKNSKQRWRIMKNTAS.AVIVGS.GIDWAR...DPKLLEIVLD........
A0A023AN74_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
G4MS99_MAGO7/128-234                 ..................................................................a-VANQTT.ALHETLDKLTSVEADSLALS...RKNVE..LAAEM..LDLVQEHEARRk.............gvTADEDPD.TAAEIR.RLEGQVQASRRRWRIMKGTAG.AVVVGS.GVDWVG...DPVLRDVVLD........
W9Q501_FUSOX/124-227                 ..................................................................s-VATQAA.KTNKVLSVLTNVQSNTLRKS...RENVT..SAAEM..LELAEQVKLKK................RVPPNSK.MMQEQE.ELEADVKASKQRWRVMKGVAS.GIIVGS.GIDWVH...DDELQDVVLD........
A0A022ZU96_TRIRU/134-237             ..................................................................a-YENMLT.TYTTCIRKLSSTEVSNIQNI...KQNQE..LVQSL..LKLTNSEKSAD................EEIPDLE.LKEELN.SLKSENKQKKAQWTRIKRIVS.ASVAAS.GVDWAS...DEKLERLVLD........
W4YCN7_STRPU/261-305                 .................................................................lg-------.--------------------...-----..-----..-----------................-------.------.QQQEKLDDLISHITMEKGILQ.GLIIGS.GVNWAK...DPALKEVVI-g.......
C1GTZ3_PARBA/79-182                  ..................................................................i-YENLSR.AHASCIQTLSDAKVENIQHN...EKNQQ..MVQTL..LGLTSAEKTWR................EEITDPK.LRAQLE.TVEKECKAEQANWVTIKRIVS.AAIVAS.GIDWAE...DEKLCDLVVD........
H1V387_COLHI/124-228                 .................................................................al--SKTSS.DIRSAVDELTDVEAESLRVG...RRNIE..LAAEV..LRLAKETEMRR...............tGETDDPA.VQAEMA.RLQVELKSSRQRWKVMKGTAS.AVVVGS.GVDWAR...DEALTDIVLD........
M7P2Q2_PNEMU/141-244                 ..................................................................n-LLNLHN.ILLKNEKKIVPLQKEVLNLF...LKNKE..KVNKI..MEIITNIKDRE................EKILSVL.EKQQKE.KLIKEMNDIKNRAIIVKNCLQ.GIILES.GIDWYG...NEHWRNIMLK........
L8IWN4_9CETA/136-236                 ..................................................................l-IMKSQQ.ETWDLEEKLLDVRKKRLQLK...QASER..KLLEI..---QTEKNKQK................DDLDSME.NSDKIK.AIQQNLETEIQITTVIQHVFQ.NLILGS.KVNWAE...DPALKETVLQ........
C5FS81_ARTOC/126-229                 ..................................................................a-YENIMT.SHTACIRELSSAEVANIQSI...QKNQE..LVQTL..LELTRNEKSLD................DNISDPQ.LKEELD.SLRTENKQKKAHWTRIKRIVS.ASIAAS.GVDWAS...DEKLENLVLD........
U6CPQ7_NEOVI/139-239                 ..................................................................l-IMKSHQ.ESWDLEEKLLDVRKKRLQLK...QASES..KLLEI..---QTEKNKQK................DDLAVME.NSDKIK.AIQQNLQMEIQITTVIQHVFQ.NLILGS.KANWAE...DPAFKETVLQ........
S8AUN6_PENO1/132-235                 .................................................................aq--ENLSS.AHDLILKQLDELKVANLKIN...QENQE..LVREL..LELTKDDSSWR................ERLEDTN.LKSQLD.QLEKEYRRSKAKWDTMKNIAS.AIVVSS.GLDWAN...DDTLRALVLD........
T5AIQ5_OPHSC/121-225                 ..................................................................s-VARQAA.DVETLRSQLTQTQADTARIS...RKNVE..LAAEL..CELADRAKQKR...............tGRLDSAE.TQSAVA.RLEDEVASRRKRWRVIKGVAS.GIVFGS.GIDWAR...DDELCDMVLD........
#=GC seq_cons                        ..................................................................s.h.p.tp.ptpshhcpLsslctcslphp...ppNpp..lstcl..htLspptpppc................pplss.c.hppclc.plcpclctp+pphpllKslhp.ulIlGS.GlsWAc...DppLcclVLc........
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