GenomeNet

Database: Pfam
Entry: CENP-X
LinkDB: CENP-X
Original site: CENP-X 
#=GF ID   CENP-X
#=GF AC   PF09415.5
#=GF DE   CENP-S associating Centromere protein X
#=GF PI   DUF2008;
#=GF AU   Mistry J, Wood V
#=GF SE   manual
#=GF GA   25.00 25.00;
#=GF TC   26.10 25.50;
#=GF NC   24.10 24.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   19620631
#=GF RT   The CENP-S complex is essential for the stable assembly of outer
#=GF RT   kinetochore structure.
#=GF RA   Amano M, Suzuki A, Hori T, Backer C, Okawa K, Cheeseman IM,
#=GF RA   Fukagawa T;
#=GF RL   J Cell Biol. 2009;186:173-182.
#=GF DR   INTERPRO; IPR018552;
#=GF CC   The centromere, essential for faithful chromosome segregation
#=GF CC   during mitosis, has a network of constitutive
#=GF CC   centromere-associated (CCAN) proteins associating with it during
#=GF CC   mitosis. So far in vertebrates at least 15 centromere proteins
#=GF CC   have been identified, which are divided into several subclasses
#=GF CC   based on functional and biochemical analyses. These provide a
#=GF CC   platform for the formation of a functional kinetochore during
#=GF CC   mitosis. CENP-S is one that does not associate with the
#=GF CC   CENP-H-containing complex but rather interacts with CENP-X to
#=GF CC   form a stable assembly of outer kinetochore proteins that
#=GF CC   functions downstream of other components of the CCAN. This
#=GF CC   complex may directly allow efficient and stable formation of the
#=GF CC   outer kinetochore on the CCAN platform.
#=GF SQ   170
#=GS G7PTB4_MACFA/11-78    AC G7PTB4.1
#=GS Q9ZV97_ARATH/80-145   AC Q9ZV97.1
#=GS G1MG80_AILME/15-85    AC G1MG80.1
#=GS G3PAR2_GASAC/8-78     AC G3PAR2.1
#=GS G0S1Y7_CHATD/96-163   AC G0S1Y7.1
#=GS A2AC07_MOUSE/44-114   AC A2AC07.1
#=GS Q25AJ9_ORYSA/49-111   AC Q25AJ9.1
#=GS G8ZRF3_TORDC/6-88     AC G8ZRF3.1
#=GS G8JU54_ERECY/10-91    AC G8JU54.1
#=GS G8BUI6_TETPH/11-107   AC G8BUI6.1
#=GS Q2GNA9_CHAGB/125-192  AC Q2GNA9.1
#=GS D8M6N7_BLAHO/1-56     AC D8M6N7.1
#=GS E4V2E6_ARTGP/123-209  AC E4V2E6.1
#=GS H0X057_OTOGA/10-77    AC H0X057.1
#=GS E7F1X6_DANRE/11-81    AC E7F1X6.1
#=GS F0W0M8_9STRA/30-88    AC F0W0M8.1
#=GS C1DZY6_MICSR/50-112   AC C1DZY6.1
#=GS Q75CS7_ASHGO/14-95    AC Q75CS7.1
#=GS H6C4D9_EXODN/196-279  AC H6C4D9.1
#=GS F0W0M9_9STRA/25-83    AC F0W0M9.1
#=GS E9GIB9_DAPPU/18-88    AC E9GIB9.1
#=GS F4IBV2_ARATH/16-86    AC F4IBV2.1
#=GS D5GIJ6_TUBMM/10-75    AC D5GIJ6.1
#=GS F2SAV8_TRIT1/122-208  AC F2SAV8.1
#=GS CENPX_CHICK/9-79      AC P0DJH7.1
#=GS H2APT8_KAZAF/4-78     AC H2APT8.1
#=GS Q0V0M7_PHANO/100-176  AC Q0V0M7.1
#=GS C0SEI9_PARBP/107-194  AC C0SEI9.1
#=GS G2QNG9_THIHA/23-90    AC G2QNG9.1
#=GS C4YN38_CANAW/19-86    AC C4YN38.1
#=GS G4MKQ9_MAGO7/207-274  AC G4MKQ9.1
#=GS I1RPP6_GIBZE/69-136   AC I1RPP6.1
#=GS Q6FQU7_CANGA/71-149   AC Q6FQU7.1
#=GS E3QL67_COLGM/78-145   AC E3QL67.1
#=GS F0X7C4_GROCL/119-187  AC F0X7C4.1
#=GS G3PAR4_GASAC/11-81    AC G3PAR4.1
#=GS B6QBK2_PENMQ/142-222  AC B6QBK2.1
#=GS E3M6S7_CAERE/6-77     AC E3M6S7.1
#=GS I1MUK5_SOYBN/38-101   AC I1MUK5.1
#=GS G0RJK7_HYPJQ/65-132   AC G0RJK7.1
#=GS G3AIK0_SPAPN/10-77    AC G3AIK0.1
#=GS H2Y0F9_CIOIN/9-82     AC H2Y0F9.1
#=GS CENPX_HUMAN/11-81     AC A8MT69.1
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRB L; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRA H; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRA E; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRB M; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRA F; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRB N; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRB K; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRB J; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRB O; 11-81;
#=GS CENPX_HUMAN/11-81     DR PDB; 4DRA G; 11-81;
#=GS Q8L7N3_ARATH/41-104   AC Q8L7N3.1
#=GS F2Q2G6_TRIEC/122-208  AC F2Q2G6.1
#=GS Q6MWL8_NEUCS/137-213  AC Q6MWL8.1
#=GS G3MGF2_9ACAR/72-142   AC G3MGF2.1
#=GS C5DYA6_ZYGRC/43-121   AC C5DYA6.1
#=GS I1K065_SOYBN/40-103   AC I1K065.1
#=GS Q4SGM6_TETNG/54-124   AC Q4SGM6.1
#=GS B6K2J4_SCHJY/9-87     AC B6K2J4.1
#=GS Q20071_CAEEL/6-77     AC Q20071.1
#=GS G2XBK4_VERDV/80-147   AC G2XBK4.1
#=GS F2QUP4_PICP7/7-103    AC F2QUP4.1
#=GS D7SHE7_VITVI/116-179  AC D7SHE7.1
#=GS C5YAT3_SORBI/50-112   AC C5YAT3.1
#=GS H2NV42_PONAB/29-63    AC H2NV42.1
#=GS A6RNU3_BOTFB/166-238  AC A6RNU3.1
#=GS B2WK03_PYRTR/117-193  AC B2WK03.1
#=GS YD160_YEAST/3-80      AC Q3E829.1
#=GS YD160_YEAST/3-80      DR PDB; 3V9R D; 3-80;
#=GS YD160_YEAST/3-80      DR PDB; 3V9R B; 3-80;
#=GS B7Q7G6_IXOSC/42-109   AC B7Q7G6.1
#=GS I1C307_RHIO9/2-64     AC I1C307.1
#=GS B6GVY1_PENCW/138-217  AC B6GVY1.1
#=GS G2RGB0_THITE/131-198  AC G2RGB0.1
#=GS C5E218_LACTC/6-86     AC C5E218.1
#=GS Q5ACP8_CANAL/19-86    AC Q5ACP8.1
#=GS C7GL10_YEAS2/3-80     AC C7GL10.1
#=GS B3LH48_YEAS1/3-80     AC B3LH48.1
#=GS G9NCR8_HYPVG/63-130   AC G9NCR8.1
#=GS G3J304_CORMM/68-135   AC G3J304.1
#=GS C0NEG5_AJECG/146-230  AC C0NEG5.1
#=GS CENPX_MOUSE/8-78      AC Q8C4X1.1
#=GS E3KHN0_PUCGT/27-124   AC E3KHN0.2
#=GS F9F534_FUSOF/67-127   AC F9F534.1
#=GS CENPX_BOVIN/9-79      AC Q2NKU0.1
#=GS G1TJ11_RABIT/9-79     AC G1TJ11.1
#=GS Q5BES3_EMENI/390-468  AC Q5BES3.1
#=GS D8S7E0_SELML/3-55     AC D8S7E0.1
#=GS Q7SC05_NEUCR/127-203  AC Q7SC05.1
#=GS E5A755_LEPMJ/107-183  AC E5A755.1
#=GS A7E683_SCLS1/184-253  AC A7E683.1
#=GS D0MYV5_PHYIT/44-110   AC D0MYV5.1
#=GS D4D033_TRIVH/121-189  AC D4D033.1
#=GS I1G6Y8_AMPQE/8-78     AC I1G6Y8.1
#=GS G3AXH2_CANTC/10-87    AC G3AXH2.1
#=GS G6CZ62_DANPL/22-97    AC G6CZ62.1
#=GS E3RJK9_PYRTT/117-193  AC E3RJK9.1
#=GS C6HND1_AJECH/146-217  AC C6HND1.1
#=GS G7XK90_ASPKW/141-218  AC G7XK90.1
#=GS A2QA97_ASPNC/139-216  AC A2QA97.1
#=GS G7NHB6_MACMU/11-78    AC G7NHB6.1
#=GS F8MR86_NEUT8/143-219  AC F8MR86.1
#=GS C1H3C0_PARBA/136-216  AC C1H3C0.1
#=GS G3R7G4_GORGO/2-72     AC G3R7G4.1
#=GS F2T007_TRIRC/122-208  AC F2T007.1
#=GS G9P776_HYPAI/61-128   AC G9P776.1
#=GS B8M3E1_TALSN/143-224  AC B8M3E1.1
#=GS I1PMB7_ORYGL/49-111   AC I1PMB7.1
#=GS F4RQY9_MELLP/21-105   AC F4RQY9.1
#=GS C5GM46_AJEDR/140-227  AC C5GM46.1
#=GS H1UY16_COLHI/83-150   AC H1UY16.1
#=GS CENPX_PONAB/11-81     AC Q5RBU1.1
#=GS H3E0V9_PRIPA/16-82    AC H3E0V9.1
#=GS F7GUG0_CALJA/11-76    AC F7GUG0.1
#=GS A6ZXG8_YEAS7/3-80     AC A6ZXG8.1
#=GS G5BJ89_HETGA/9-77     AC G5BJ89.1
#=GS H2RCP6_PANTR/11-81    AC H2RCP6.1
#=GS Q6CSZ2_KLULA/6-78     AC Q6CSZ2.1
#=GS E9ERE9_METAR/62-129   AC E9ERE9.1
#=GS G3GXC6_CRIGR/34-104   AC G3GXC6.1
#=GS C1GH76_PARBD/109-196  AC C1GH76.1
#=GS F7FSW5_MACMU/11-81    AC F7FSW5.1
#=GS C5P8E3_COCP7/118-204  AC C5P8E3.1
#=GS F2TBJ2_AJEDA/140-227  AC F2TBJ2.1
#=GS D7KVV0_ARALL/41-104   AC D7KVV0.1
#=GS A9PI92_POPTR/43-103   AC A9PI92.1
#=GS B8MZ13_ASPFN/130-208  AC B8MZ13.1
#=GS H9KVI1_CHICK/10-80    AC H9KVI1.1
#=GS E9D3R3_COCPS/118-204  AC E9D3R3.1
#=GS C5YAT1_SORBI/49-111   AC C5YAT1.1
#=GS E9PW01_MOUSE/41-111   AC E9PW01.1
#=GS A2FX12_TRIVA/12-80    AC A2FX12.1
#=GS A9NXK2_PICSI/52-121   AC A9NXK2.1
#=GS H3CWL8_TETNG/12-82    AC H3CWL8.1
#=GS F7W9L7_SORMK/137-213  AC F7W9L7.1
#=GS G5AEQ5_PHYSP/46-110   AC G5AEQ5.1
#=GS B2B1H7_PODAN/182-249  AC B2B1H7.1
#=GS G0W3G5_NAUDC/36-122   AC G0W3G5.1
#=GS G0P5M1_CAEBE/1-65     AC G0P5M1.1
#=GS B5YLU9_THAPS/27-130   AC B5YLU9.1
#=GS B9WN18_CANDC/17-84    AC B9WN18.1
#=GS F0UFF0_AJEC8/147-230  AC F0UFF0.1
#=GS F4PWS8_DICFS/15-84    AC F4PWS8.1
#=GS G4UV78_NEUT9/143-219  AC G4UV78.1
#=GS A2DLP6_TRIVA/12-80    AC A2DLP6.1
#=GS G3VAX2_SARHA/9-79     AC G3VAX2.1
#=GS H0W6I2_CAVPO/9-79     AC H0W6I2.1
#=GS C8Z6E2_YEAS8/3-80     AC C8Z6E2.1
#=GS C9SLB7_VERA1/1-57     AC C9SLB7.1
#=GS D2GVE5_AILME/87-145   AC D2GVE5.1
#=GS E9E195_METAQ/62-116   AC E9E195.1
#=GS A1D1B8_NEOFI/139-219  AC A1D1B8.1
#=GS B9RAQ7_RICCO/39-98    AC B9RAQ7.1
#=GS E9CDC0_CAPO3/10-80    AC E9CDC0.1
#=GS Q4WRE9_ASPFU/136-216  AC Q4WRE9.2
#=GS G2WC02_YEASK/3-80     AC G2WC02.1
#=GS Q019W8_OSTTA/19-88    AC Q019W8.1
#=GS F0ZTX8_DICPU/4-56     AC F0ZTX8.1
#=GS A3GI84_PICST/10-107   AC A3GI84.2
#=GS C1MIX6_MICPC/51-110   AC C1MIX6.1
#=GS Q7XUQ1_ORYSJ/49-111   AC Q7XUQ1.2
#=GS C5MID8_CANTT/9-96     AC C5MID8.1
#=GS C5FBD6_ARTOC/117-203  AC C5FBD6.1
#=GS B0XNW4_ASPFC/136-216  AC B0XNW4.1
#=GS G2XS27_BOTF4/166-238  AC G2XS27.1
#=GS G1XJQ9_ARTOA/34-96    AC G1XJQ9.1
#=GS H2ZDL5_CIOSA/4-77     AC H2ZDL5.1
#=GS A7TL11_VANPO/8-87     AC A7TL11.1
#=GS I1IYX3_BRADI/47-110   AC I1IYX3.1
#=GS A1CNH8_ASPCL/139-223  AC A1CNH8.1
#=GS H3GXK2_PHYRM/46-110   AC H3GXK2.1
#=GS H9J3A8_BOMMO/591-660  AC H9J3A8.1
#=GS C5JYD2_AJEDS/140-227  AC C5JYD2.1
#=GS A8WRA8_CAEBR/6-77     AC A8WRA8.1
#=GS YQEC_SCHPO/9-88       AC O74896.1
#=GS C4R695_PICPG/7-103    AC C4R695.1
#=GS Q2UQY1_ASPOR/130-194  AC Q2UQY1.1
#=GS D4B147_ARTBC/121-189  AC D4B147.1
#=GS Q6BJ85_DEBHA/16-86    AC Q6BJ85.1
#=GS C4JIQ2_UNCRE/121-198  AC C4JIQ2.1
G7PTB4_MACFA/11-78               ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMAELLKIFVVEA.AVRGVR......QARAEDTLR..................................-VDVDQLEK.VLPQLV---..................................
Q9ZV97_ARATH/80-145              .............cn-------LFS..QR.ERS..DAIDAT..EA..EVALGTTKKNRLASEA.VQRAAI......IAEAEGMEK..................................-IEATHLER.ILPQLLLDF..................................
G1MG80_AILME/15-85               ...............PQDLVSKLLR..LH.FTD..SKTKVS..GD..ALWLMAELLTIFVVET.AVRSVR......QAQAEDLAL..................................-VDVDQLEK.VLPQLLLDF..................................
G3PAR2_GASAC/8-78                ..............k-KETVSKLLS..SF.FKE..DKTRLS..GD..AVLLMTEMLKIFVQEA.AVRSQK......QAESEDCDQ..................................-VDIEHFEK.ILPQLLLDF..................................
G0S1Y7_CHATD/96-163              ..............h-PELLTRILH..EF.FEK..EDTRIT..KD..ANAAVAKYVDIFVREA.IARAAV......-ERGRG---..................................FLEVEDLEK.IAPQLLMDL..................................
A2AC07_MOUSE/44-114              .............hl--ELVSRLLH..LH.FRD..CKTKVS..GD..ALQLMAEFLRIFVLEA.AVRGVW......QAQAEDLDV..................................-VEVDQLEK.VLPQLLLDF..................................
Q25AJ9_ORYSA/49-111              ............pet----------..-S.RRN..RSATAN..AS..ALKVSCELLRIFVTEA.VQRSAF......IAEAEGTTT..................................-IEPTHLER.VLPQLLLDF..................................
G8ZRF3_TORDC/6-88                ...............PKETIARTFQ.vGA.FEN..ESTNIT..DE..TVGMMQKYMEVFVREA.VLRSSA......NKEQIKVEHsgaqr........................nsneiVLTHEDLEN.ITGLLLLDM..................................
G8JU54_ERECY/10-91               ...............PSDTIARIFQ.lCS.FTQ..DSTRIT..ED..TITLTEKYIKLFVREA.VLRSLE......NKDKVKKEDgkgs.........................liegpVLHHTDLEE.ISGILLLDF..................................
G8BUI6_TETPH/11-107              ...............PKDTIARILQ.lES.FG-..EETRIS..AE..SVGILQKYMELFVREA.VLRSIE......-NREQKQSNiealkkapakanp........dqlqtfqhsfngiELTHEDLEE.ISGLLLLDM..................................
Q2GNA9_CHAGB/125-192             ...............PPELLTRILH..AF.FER..EGTRIT..RD..ANAAVARYMDIFVREA.IARAAV......-ERSSG---..................................FLEVEDLEK.IAPQLLMDL..................................
D8M6N7_BLAHO/1-56                ..............m----------..--.--K..ESTKIS..RN..GAIAASEYLRLFVVEA.LERAHK......QAENSDV--..................................-VTARDIQK.ILPELLLDF..................................
E4V2E6_ARTGP/123-209             .............dy--KLITTILH.eVA.FKK..QKTRVT..KD..GVKLFTKYIESFVTEA.VSRSIE......EKRASNTAAmatlgtr....................tdldhrnYLETEDLER.AYPQLMLDF..................................
H0X057_OTOGA/10-77               ..............s-PELVSKLLH..LH.FKD..AKTKVS..GD..ALQLMVELLKIFVVEA.AVRGVR......QAQAEDVAL..................................-VDVDQLEK.VLPQLV---..................................
E7F1X6_DANRE/11-81               ..............k-KETVAKLLS..RS.FRE..DKTRVS..SD..AVVLVAEMLKVFVEEA.TRRAIK......QASSEDCDT..................................-VTIEHFEK.ILPQLLLDF..................................
F0W0M8_9STRA/30-88               .........hsvhis----------..--.---..---KIQ..QD..ALRLSAEFLELFLKEA.LHRAQM......EAMMEDAST..................................-VEPHHVEE.ILAQLLLDF..................................
C1DZY6_MICSR/50-112              .........nnrsgs----------..--.--A..KKLNIK..DE..AIVASAEVVRMFVAEL.VHRAAE......GAKEDGEDT..................................-VDGTHLER.VLPQFLLDF..................................
Q75CS7_ASHGO/14-95               ...............PTDTIARLFH.tCS.FTQ..DSTKIT..ED..AVTLVERYMKLFIREA.VLRSLE......NKEKVKQETrads.........................faegpVLQHTDLEE.ISGVLILDF..................................
H6C4D9_EXODN/196-279             .............pl--PLIHHIMQ..AQ.FTT.pEKTTVS..AD..ARALFGMYIEIFVKEC.IRRCVD......EKKDREAAGgaqas.......................vgvdsgWLELEDLER.VATQLCLDF..................................
F0W0M9_9STRA/25-83               .........hsvhis----------..--.---..---KIQ..QD..ALRLSAEFLELFLKEA.LHRAQM......EAMMEDAST..................................-VEPHHVEE.ILAQLLLDF..................................
E9GIB9_DAPPU/18-88               ............keg---LIHELMK..MY.TTN..HKTKIG..NE..AVTAVNEIMLKFLNEV.VWRAMN......QAHNEGLNN..................................-VNLDNIEK.ILPQLLLDF..................................
F4IBV2_ARATH/16-86               ............fkh---IWARRFR..ER.ERS..DAIDAT..EA..EVALGTTKKNRLASEA.VQRAAI......IAEAEGMEK..................................-IEATHLER.ILPQLLLDF..................................
D5GIJ6_TUBMM/10-75               ..............s-TQLVQRLLT..EN.FED..RKTRIS..QP..ALNVVQEYTKIFVREA.IWRAAA......IRKEEQGGE..................................---------.---------gglknmsaflea......................
F2SAV8_TRIT1/122-208             .............dy--KLVTTILH.eVA.FKK..KKTRIT..KD..GVKLFTKYIESFVTEA.VSRSIE......EKRVNSAASmatsatr....................tdiehsnYLETEDLER.AYPQLMLDF..................................
CENPX_CHICK/9-79                 ..............r-KETVERLLR..LH.FRD..GRTRVN..GD..ALLLMAELLKVFVREA.AARAAR......QAQAEDLEK..................................-VDIEHVEK.VLPQLLLDF..................................
H2APT8_KAZAF/4-78                ...............PKETISRILLnkLN.ENG..ENFSIN..TE..TVESVTKYTDVLIEEM.VLRSLE......NKENIAEAT.................................pTLDVDDLEK.IIGLLLLDM..................................
Q0V0M7_PHANO/100-176             ...............PAPLLARLLY..EN.FED..PNTQIQ..KG..AMNLVEKYMEIFVREA.FARAKQ......-ERELSVKAggi............................sdgFLQVEDLEK.LAPQLVLDF..................................
C0SEI9_PARBP/107-194             ...............PSKLLTTLLH..RH.FQD..EKTKIA..KD..AGRVVAKYVDIFVREA.LARAAY......ERTQVEESRsdspearg..................rarakvdsYLEIEDLEK.LAPQMVLDF..................................
G2QNG9_THIHA/23-90               ...............PPELLTRILH..GF.FGR..EETRIT..RD..ANAAVARYVDVFVREA.IARAAV......-EREGG---..................................FLEVEDLEK.IAPQLLMDL..................................
C4YN38_CANAW/19-86               ...............PVTTIARLFK.eLS.FKD..PQTRIT..LS..TLELSSEYIKLFINEA.IIRANE......ERIDEGDTL..................................-VQIDGIDN.VTS------ta................................
G4MKQ9_MAGO7/207-274             ...............PPELLRRLLH..EA.FDK..DTTRVS..KE..ANAAVARYFDIFVQEA.IARTAA......--ERNG--R..................................FLEVEDLEK.VAPQLLLDL..................................
I1RPP6_GIBZE/69-136              ...............PAELLTRLLH..EF.FSK..DATRIS..RD..ANAAAGKYFDVFVREA.IARAAV......----EKEAG..................................FLEVDDLEK.ISPQLLLDL..................................
Q6FQU7_CANGA/71-149              ...............PQDTIARVLQ.vAA.FKD..KKTRIE..SD..VVDALQRYIDVFAREA.VLRSIEhh..daSQEG----Leqe............................qdkEITHTDLEN.IAGLLLLDM..................................
E3QL67_COLGM/78-145              ...............PPELLTRLLH..EF.FEK..DDTRLS..KD..ANAAAGKYMDVFVREA.IARCIH......-ERPG---G..................................FLEVEDLEK.IAPQLLMDF..................................
F0X7C4_GROCL/119-187             ...............PPELLTRLLH..HF.FSK..PNSRIT..QD..ANTSVGKYMEIFIREA.VARSMA......-ERRDGS--..................................FLDVDVLQK.VAAQLIMDM..................................
G3PAR4_GASAC/11-81               ..............k-KETVSKLLS..SF.FKE..DKTRLS..GD..AVLLMTEMLKIFVQEA.AVRSQK......QAESEDCDQ..................................-VDIEHFEK.ILPQLLLDF..................................
B6QBK2_PENMQ/142-222             ...............PPKLLTTILH..HH.FQN..KKTKIT..KD..ANEVVAKYMNIFVREA.LARAAF......ERADAASKDgggk.........................yagdgFLEVEDLEK.LAPQMLLDF..................................
E3M6S7_CAERE/6-77                ..............k-QSTVRSMLT.vAR.RGK..KRLNLD..SD..ALAVLTALINLLAQET.IARTAQ......TAANTGDRQ..................................-VTKEHLKR.VIAQIMLDF..................................
I1MUK5_SOYBN/38-101              ...........gvgt----------..-S.KKN..RSTSAN..AN..ALKLTSELLRIFITEA.VQRAAA......TAEVEGASQ..................................-LEPTHLEI.ILPQLLLDF..................................
G0RJK7_HYPJQ/65-132              ...............PRALLTRILH..EF.FTK..DATRMS..RD..ANAAVGKYVDIFVREA.IARTAV......----EKRGG..................................FLEVEDLEK.VAPQLLLDL..................................
G3AIK0_SPAPN/10-77               ...............PVATIARIFR.eLS.FKN..DSTRIT..MD..TLELSSEYIKLFINEA.IIRSNQ......ERLDEGDSL..................................-TKVDGIDN.VNQ------tq................................
H2Y0F9_CIOIN/9-82                ..........ssefa-----VKLLE..KH.FTD.qNSTKIS..TKdgTGRKCAELLSVFVAEA.ASRAAK......QAENEDAAI..................................-CEIEHVEK.ILPQLLLDF..................................
CENPX_HUMAN/11-81                ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMVELLKVFVVEA.AVRGVR......QAQAEDALR..................................-VDVDQLEK.VLPQLLLDF..................................
#=GR CENPX_HUMAN/11-81     SS    ..............--HHHHHHHHH..TT.-SS..TT-EE-..HH..HHHHHHHHHHHHHHHH.HHHHHH......HHHHTT-SS..................................-B-HHHHHH.HHHHHHHH-..................................
Q8L7N3_ARATH/41-104              ..........algtt----------..--.KKN..RLASAN..AN..ALKLSCELLKSFVSEA.VQRAAI......IAEAEGMEK..................................-IEATHLER.ILPQLLLDF..................................
F2Q2G6_TRIEC/122-208             .............dy--KLVTTILH.eVA.FKK..KKTRIT..KD..GVKLFTKYIESFVTEA.VSRSIE......EKRVNSAASmatsatr....................tdiehsnYLETEDLER.AYPQLMLDF..................................
Q6MWL8_NEUCS/137-213             ...............PSELLTRLLY..EF.FES..DKTKIT..KD..ANEAVARYVDIFVREA.IARSVV......-EREGGNGTtsg............................gggFLEVEDLEK.IAPQLLLDL..................................
G3MGF2_9ACAR/72-142              ..............k-AKTIQELMK..MN.FEH..DKTRIS..AD..ALKMLTELFRIMTIET.VMRATD......QAKIQCDTE..................................-VRPEHLEK.VLPQLMLDF..................................
C5DYA6_ZYGRC/43-121              ...............PKETIVRILK.lQA.FEH..ESTTIT..EE..TVTMLQKYLEVFVREA.VQRSVA......NKDSQGSHGdgd............................geiQLNHEDLEK.ITGMLLLDM..................................
I1K065_SOYBN/40-103              ...........gvgt----------..-S.KKN..RSTSAN..AN..ALKLTSELLRIFITEA.VQRAAT......IAEAEGASQ..................................-IEPTHLEI.ILPQLLLDF..................................
Q4SGM6_TETNG/54-124              ..............e-QETVSKLLA..RF.FKE..DKTRLG..GD..AAVLMAEMLRIFVREA.AVRSQK......QAESEDCDQ..................................-VDIEHFEK.ILPQLLLDF..................................
B6K2J4_SCHJY/9-87                .............sl--NTLARILT..LY.FSP.eNRTKIT..PT..ALTLIAQYLKIYTKEA.VCRAYE......DKKEKMMTGdd.............................devVLEIEDLENgVAAQLALDF..................................
Q20071_CAEEL/6-77                ..............k-QSTVRSMLI.vAR.RGK..KRLNLD..PD..ALAVLTALINLLAQES.VARAAQ......SAANTGSRH..................................-VTKEHLKR.VIAQLMLDF..................................
G2XBK4_VERDV/80-147              .............ps--GLVANLLK..EM.FAR..EETRMT..EG..ASLAAARYIDVFVREA.IARCVH......-EREGG---..................................FLEVDDLEK.ISAQLLMDF..................................
F2QUP4_PICP7/7-103               ..............s-KTTLARLFH.tVA.FEE..PDTRIS..SK..TLELSIEYLKIFTKEA.VIRADE......VRRDRNGQVrskyniklenve..........dqpientdsnggILDVNHLSQ.ISGSLILDF..................................
D7SHE7_VITVI/116-179             ...........gaat----------..-S.KKN..RPTSAN..AN..ALKLSCELLRVFVIEA.VERAAT......IAEAEGVNK..................................-IEATHLER.ILPQLLLDF..................................
C5YAT3_SORBI/50-112              ............pet----------..-S.RRN..RSTTAN..AN..ALKVSCELLRIFVSEA.IQRSAF......IAEAEDGTV..................................-IEPTHLER.VLPQLLLDF..................................
H2NV42_PONAB/29-63               ...............----------..--.---..------..--..-------------KEA.AVRGVR......QAQAEDALR..................................-VDVDQLEK.VLPQLLLDF..................................
A6RNU3_BOTFB/166-238             ...............PNDLLSKIMH..EL.FAE..PNTRIS..KE..ANKAVGKYMDTFVREA.IARVRY......TERGSGRGG.................................gFWEVEDLEK.MAPQLLLDF..................................
B2WK03_PYRTR/117-193             ..............p-RPLLARLLL..EN.FDD..PNMQIQ..TG..AMKLVGKYIDIFVTEA.FLRSKD......ERESAAKETgs.............................vdsFLQVEDLEK.LAPQLVLDF..................................
YD160_YEAST/3-80                 ..............s-KEALIKILS..QN.EGG..NDMKIA..DE..VVPMIQKYLDIFIDEA.VLRSLQsh..kdINGERGDKSp................................lELSHQDLER.IVGLLLMDM..................................
#=GR YD160_YEAST/3-80      SS    ..............--CHHHHHHHT..TT.S-S..S--EE-..TT..THHHHHHHHHHHHHHH.HHHHHHHH..HH-XXXXXXXXX................................XEE-HHHHHH.HCHCHHCHT..................................
B7Q7G6_IXOSC/42-109              ..............k-TKTIQELML..MG.FQD..EKTKMN..AQ..ALKLTCEILRLLAHEG.AARASM......QAKLQGDHE..................................-VTLEHLEK.ILPQLV---..................................
I1C307_RHIO9/2-64                ...........rnvv----------..--.---..----AN..KE..AIQLSSEFLRLFVVEA.VHRSSAeleamsIA------Sqtt............................nkkVINVEALER.ILPQLLLDF..................................
B6GVY1_PENCW/138-217             ...............PSKLLTRLLH..QH.FQN..EKTKVA..KD..ANNVVAKYVDVFVREA.IARAAY......ERAESGGNAggrg..........................vgdgFLEVEDLEK.MAPQLTMDF..................................
G2RGB0_THITE/131-198             ...............PPELLTRILH..EF.FEK..EGTRIT..RD..ANAAVARYMDVFVREA.IARAAV......-ERASG---..................................FLEVEDLEK.IAPQLLMDL..................................
C5E218_LACTC/6-86                ...............PSDTIARIFQ.tCS.FKD..DSTRIT..ES..TLSLVDAYLEVFVREA.LLRSIE......NKEQVKSEHqdql..........................gdqvVLTHKDLER.VSGLLLLDM..................................
Q5ACP8_CANAL/19-86               ...............PVTTIARLFK.eLS.FKD..PQTRIT..LS..TLELSSEYIKLFINEA.IIRANE......ERIDEGDTL..................................-VQIDGIDN.VTS------ta................................
C7GL10_YEAS2/3-80                ..............s-KEALIKILS..QN.EGG..NDMKIA..DE..VVPMIQKYLDIFIDEA.VLRSLQsh..kdINGERGDKSp................................lELSHQDLER.IVGLLLMDM..................................
B3LH48_YEAS1/3-80                ..............s-KEALIKILS..QN.EGG..NDMKIA..DE..VVPMIQKYLDIFIDEA.VLRSLQsh..kdINGERGDKSp................................lELSHQDLER.IVGLLLMDM..................................
G9NCR8_HYPVG/63-130              ...............PKALLTRILH..EF.FAK..EATRMS..RD..ANAAVGKYVDIFVREA.IARTAV......----EKRGG..................................FLEVEDLEK.VAPQLLLDL..................................
G3J304_CORMM/68-135              ...............PKDLLTRILH..DL.FEK..DATRVS..RD..ANAAVGKYVDVFVREA.IARSAV......----EKRSG..................................FLEVEDLEK.IAPQLLLDL..................................
C0NEG5_AJECG/146-230             ..............k-PKLLTTLLH..RH.FQD..DKTKIT..KD..AVRALAKYVDIFVREA.LARASY......-ERAEGQSGksasrdtr.................ggararvdnYLEIEDLER.LAPQLL---..................................
CENPX_MOUSE/8-78                 ..............r-KELVSRLLH..LH.FRD..CKTKVS..GD..ALQLMAEFLRIFVLEA.AVRGVW......QAQAEDLDV..................................-VEVDQLEK.VLPQLLLDF..................................
E3KHN0_PUCGT/27-124              tnerktslqlmvekp----------..--.---..--PKIN..EI..SLRLSTEYLRLFAIEC.IHRATQ......VAQQEEEEEaqqaeeeknrlkda......netadenlrsalkgLIQLRHLQK.AAPGVLLDF..................................
F9F534_FUSOF/67-127              ...............PPELLTRLLH..EF.FAK..DATRIS..RD..ANAAAGKYFDVFVREA.IARAAV......----EKDGG..................................FLEVEDLEK.---------qp................................
CENPX_BOVIN/9-79                 ..............r-KELVSKLLH..LH.FKD..KKTKVS..GD..ALQLVAELLKIFVVEA.AIRSVR......QAQAEGLAH..................................-VDVEQLEK.VLPQLLLDF..................................
G1TJ11_RABIT/9-79                ..............r-KELVSKLLH..LH.FKN..DKTKVS..GD..VLQLTAELLRIFTMEApVHRVWQ......-AQAEDAVQ..................................-VGVEQLEK.VLPQLLLDF..................................
Q5BES3_EMENI/390-468             ...............PPKLLTRLLH..HH.FRS..EKTKIA..KD..ANAVVAKYIDVFVREA.VARAAF......-ERSEAQGGasggv........................giadgFL--ESCAD.IDMVLIIY-l.................................
D8S7E0_SELML/3-55                .............pa----------..--.---..-----N..AN..ALKLSCELLKLFVTEA.VGRAGI......IAEAKGKDR..................................-IEATHFER.MLPQFLLDF..................................
Q7SC05_NEUCR/127-203             ...............PSELLTRLLY..EF.FES..DKTKIT..KD..ANEAVARYVDIFVREA.IARSVV......-EREGGNGTtsg............................gggFLEVEDLEK.IAPQLLLDL..................................
E5A755_LEPMJ/107-183             ...............PAPLLARLLY..EN.FEN..EQTQIQ..KG..AMNLVGKYLDIFVREA.FARAKH......-ERELAVKGggi............................sdgFLQVEDLEK.LAPQLVLDF..................................
A7E683_SCLS1/184-253             ...............PPDLLSKIIH..EL.FTE..QNSRIS..KE..ANKTVGKYMDVFVREA.VTRIWD......---ADGRRG.................................gFWEVEDLER.MAPQLLLDF..................................
D0MYV5_PHYIT/44-110              ...aplvsaaaaasr----------..--.---..-VRKIH..AD..AVKLSAEMLRLFVVEA.FRRAQM......EAMVDDSEQ..................................-VEPQHIEQ.ILAQLLLDF..................................
D4D033_TRIVH/121-189             .............dy--KLITTILH.eVA.FKK..KKTRIT..KD..GVKLFTKYIESFATEA.VSRAIE......EKRMNNAAS..................................---------.---------matpatradiehsn....................
I1G6Y8_AMPQE/8-78                ..............r-QETVLQILK..SN.FSD..SKTKVN..ND..ALKLMKKYVDILVLET.VFRTID......QAKIEQSDA..................................-VELQHFEK.VLPKLLLDF..................................
G3AXH2_CANTC/10-87               .............nl--KTISRLFH.eLA.FNK..ENTRLS..QK..TLQLSAQYINLFIREG.ILRSND......ERLSDGDRL..................................-SHVDGIDN.---------letirgnegeeveee...................
G6CZ62_DANPL/22-97               ..............n-QDIVKELLK..SS.FQD..SQTKLS..CE..ALSLMTEIAKLLVMET.CLRAAD......LANSGNEDGqv..............................csVINADHILK.CLPQIMLDF..................................
E3RJK9_PYRTT/117-193             ..............p-RPLLARLLL..EN.FDD..ANMQIQ..TG..AMKLVGKYIDIFVTEA.FLRSKD......EREAAAKESgl.............................vdgFLQVEDLEK.LAPQLVLDF..................................
C6HND1_AJECH/146-217             ..............k-PKLLTTLLH..RH.FQN..DKTKIT..KD..AVRALAKYVDIFVREA.LARASY......-ERAEGQSG..................................---------.---------ksasrdtrgrvemiileel...............
G7XK90_ASPKW/141-218             ...............PPKLLTRLLH..HH.FQN..EKTKIA..KD..ANTVVAKYVDVFVREA.LARAAF......-ERSEAVGKgas...........................vgdgFLEVEDLEK.MAPQLVMDF..................................
A2QA97_ASPNC/139-216             ...............PPKLLTRLLH..HH.FQN..EKTKIA..KD..ANTVVAKYVDVFVREA.LARAAF......-ERSEAVGKgaa...........................vgdgFLEVEDLEK.MAPQLVMDF..................................
G7NHB6_MACMU/11-78               ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMAELLKIFVVEA.AVRGVR......QARAEDALR..................................-VDVDQLEK.VLPQLV---..................................
F8MR86_NEUT8/143-219             ...............PSELLTRLLY..EF.FES..DKTKIT..KD..ANEAVARYVDIFVREA.IARSVV......-EREGGNGTtsg............................gggFLEVEDLEK.IAPQLLLDL..................................
C1H3C0_PARBA/136-216             ...............PSKLLTTLLH..RH.FQD..EKTKIA..KD..AGRVVAKYVDIFVREA.LARAAY......ERTQVEE--..................................---------.---------srsdspevrgrarakvdsyleseehldsl.....
G3R7G4_GORGO/2-72                .............ga--ELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMVELLKVFVVEA.AVRGVR......QAQAEDALR..................................-VDVDQLEK.VLPQLLLDF..................................
F2T007_TRIRC/122-208             .............dy--KLVTTILH.eVA.FKK..KKTRIT..KD..GVKLFTKYIESFVTEA.VSRAIE......EKRVNNAASmatpatr....................tdiehsnYLETEDLER.AYPQLMLDF..................................
G9P776_HYPAI/61-128              ...............PKALLTRILH..EL.FAK..EATRMS..RD..ANAAVGKYVDVFVREA.IARAAV......----EKRGG..................................FLEVEDLEK.VAPQLLLDL..................................
B8M3E1_TALSN/143-224             ...............PPKLLTTILH..HH.FQN..SKTKIT..KD..ANEVVAKYMDIFVREA.LARAAY......ERADAANGDrgggr........................pgadgFLEVEDLEK.LAPQMLLDF..................................
I1PMB7_ORYGL/49-111              ............pet----------..-S.RRN..RSATAN..AS..ALKVSCELLRIFVTEA.VQRSAF......IAEAEGTTT..................................-IEPTHLER.VLPQLLLDF..................................
F4RQY9_MELLP/21-105              .........qtwtad------RLSS.lEA.TSE..PPPKIN..DA..ALHLSVEYLRLFTIEL.IHRANE......AAGGSEDKGnskdkd......................etdseyLIEVRHLQK.VAPGVLLDF..................................
C5GM46_AJEDR/140-227             ...............PSKLLTTLLH..RH.FQD..DKTKIA..KD..AGRVVAKYVDIFVREA.LARAAY......-ERTEGQSSksgsrdas.................grarakvdsYLEVEDLEK.LAPQMVLDF..................................
H1UY16_COLHI/83-150              ...............PPELLTRLLH..LF.FEK..DDTRLS..KD..ANAAAGRYMDIFVREA.IARCVH......-ERPG---G..................................FLEVEDLEK.IAPQLLMDF..................................
CENPX_PONAB/11-81                ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMVELLKVFVVEA.AVRGVR......QAQAEDALR..................................-VDVDQLEK.VLPQLLLDF..................................
H3E0V9_PRIPA/16-82               ....linnhrlkkgg----------..--.---..NPVNLS..QK..TLALITALAEKLMKES.IRRSIA......LCRQNGDTK..................................-VSLEHIQR.VLPQIMLDF..................................
F7GUG0_CALJA/11-76               ..............r-KELVSRLLH..AH.FKD..DKTKVS..GD..SLQLMAELLKIFVVEA.AVREVQ......QAQAEDAIL..................................-VDVDQLEK.LL-------df................................
A6ZXG8_YEAS7/3-80                ..............s-KEALIKILS..QN.EGG..NDMKIA..DE..VVPMIQKYLDIFIDEA.VLRSLQsh..kdINGERGDKSp................................lELSHQDLER.IVGLLLMDM..................................
G5BJ89_HETGA/9-77                ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMAELLRIFVVEA.AVRGVR......QAQAEDTAL..................................-VDVDQLEK.VLPQLV---c.................................
H2RCP6_PANTR/11-81               ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLVVELLKVFVVEA.AVRGVR......QAQAEDALR..................................-VDVDQLEK.VLPQLLLDF..................................
Q6CSZ2_KLULA/6-78                ..............f-STTIARILQ.tEG.FQD..SNTRIT..EE..CMQLLEPYIELFVREG.VLRSLE......NKADMLADK..................................TVDFVDLEA.VAGLLLMDF..................................
E9ERE9_METAR/62-129              ...............PRDLLTRILH..EF.FAK..DSTRIS..RD..ANAAVGKYMDIFVREA.IARAAV......-EKNAG---..................................FLEVDDLEK.IAPQLLLDL..................................
G3GXC6_CRIGR/34-104              ..............l-QELVSKLLH..LH.FRD..CKTKVS..GD..ALQLMAELLRIFVLEA.AARGVC......QAQAEDLDV..................................-VDVDQLEK.VLPQLLLDF..................................
C1GH76_PARBD/109-196             ...............PSKLLTTLLH..RH.FQD..EKTKIA..KD..AGRVVAKYVDIFVREA.LARAAY......ERTQVEESRsdspearg..................rarakvdsYLEIEDLEK.LAPQMVLDF..................................
F7FSW5_MACMU/11-81               ..............r-KELVSRLLH..LH.FKD..DKTKVS..GD..ALQLMAELLKIFVVEA.AVRGVR......QARAEDTLR..................................-VEVDQLEK.VLPQLLLDF..................................
C5P8E3_COCP7/118-204             ...............PPKLLAAIIH..HH.MKSkgEKMRIT..KD..ANRLYAKYIDIFVKEA.VARAIH......ERREKLNTDgierdr.....................srrildsYLEVEDLEK.LAPQLLLDF..................................
F2TBJ2_AJEDA/140-227             ...............PSKLLTTLLH..RH.FQD..DKTKIA..KD..AGRVVAKYVDIFVREA.LARAAY......-ERTEGQSSksgsrdas.................grarakvdsYLEVEDLEK.LAPQMVLDF..................................
D7KVV0_ARALL/41-104              ..........algtt----------..--.KKN..RLASAN..AN..ALKLSCELLKSFVSEA.VQRAAI......IAEAEGMDK..................................-IEATHLER.ILPQLLLDF..................................
A9PI92_POPTR/43-103              ............tlk----------..--.-KT..RTTSAN..SN..ALKLSCELLRIFITEA.VQRSAM......IAEAEGAGK..................................-IEGTHLER.ILPQLLLDF..................................
B8MZ13_ASPFN/130-208             ...............PPKLLTKLVH..HH.FKG..QKTKIA..KD..ANEVVAKYVDVFVREA.LARAAF......-ERAEGGKGverg..........................vgdgFLEVEDLEK.MAPQLVLDF..................................
H9KVI1_CHICK/10-80               ..............r-KETVERLLR..LH.FRD..GRTRVN..GD..ALLLMAELLKVFVREA.AARAAR......QAQAEDLEK..................................-VDIEHVEK.VLPQLLLDF..................................
E9D3R3_COCPS/118-204             ...............PPKLLAAIIH..HH.MKSkgEKMRIT..KD..ANRLYAKYIDIFVKEA.VARAIH......ERREKLNTDgierdr.....................srrildsYLEVEDLEK.LAPQLLLDF..................................
C5YAT1_SORBI/49-111              ............pet----------..-S.RRN..RSTTAN..AN..ALKVSCELLRIFVTEA.IQRSAF......IAEAEDGTV..................................-IEPTHLER.VLPQLLLDF..................................
E9PW01_MOUSE/41-111              .............hl--ELVSRLLH..LH.FRD..CKTKVS..GD..ALQLMAEFLRIFVLEA.AVRGVW......QAQAEDLDV..................................-VEVDQLEK.VLPQLLLDF..................................
A2FX12_TRIVA/12-80               ..............i-KAIIESALA..DQ.NDD..QKLRIP..PT..TVELIAEYLRCVVVEA.TERAVD......VAGDEK---..................................VIDESHLEK.ILPQLLLDI..................................
A9NXK2_PICSI/52-121              ......etelevgaa----------..AS.KKT..RTTTAN..SN..ALKLSCEFLRLFVTEA.VQRAAI......VAEVEGSTQ..................................-IEGTHLER.ILPQLLLDF..................................
H3CWL8_TETNG/12-82               ..............k-KETVSKLLA..RF.FKE..DKTRLG..GD..AAVLMAEMLRIFVREA.AVRSQK......QAESEDCDQ..................................-VDIEHFEK.ILPQLLLDF..................................
F7W9L7_SORMK/137-213             ...............PSELLTRLLY..EF.FES..DKTKIT..KD..ANEAVARYVDIFVREA.IARSVM......-EREGGNGTttg............................gggFLEVEDLEK.IAPQLLLDL..................................
G5AEQ5_PHYSP/46-110              ...lvsaaaaaarvr----------..--.---..---KIH..AD..AVKLSAEMLRLFVVEA.FRRAQM......EAMVDDSEQ..................................-VEPQHIEQ.ILAQLLLDF..................................
B2B1H7_PODAN/182-249             ...............PPELLSKIVH..EL.FEH..KETKIT..KD..ANNALSGYMDVFVREA.IARAAA......----ERKGA..................................FLEVEDLEK.VAAQLVLDL..................................
G0W3G5_NAUDC/36-122              .............ll--ETIEKILR.sES.FQN..KDTTIT..KE..TILMIQRYMDLFIKEA.VIRSYE......NKVATQVEDfddeeda....................deedktiELTHLDLER.IVGLLLMEL..................................
G0P5M1_CAEBE/1-65                ..............m--------LT.vAR.RGK..KRINLE..PD..ALAAVAALINILAQET.FARAAQ......SAANTGDRK..................................-VTRDHLRK.IIAQIMLDF..................................
B5YLU9_THAPS/27-130              ...........pgdl----TRKCLQ..L-.-HH..PYQKIA..SD..AVDLSSELLKLLVVEA.RRRAAI......EAECDAAVSdtgnksesdgsqswmkdsyedendtlttkkkkvvEIRADHISK.IAAELLMDL..................................
B9WN18_CANDC/17-84               ...............PVTTIARLFK.eLS.FKD..PQTRIT..LS..TLELSSEYIKLFINEA.IIRANE......ERIDEGDTL..................................-IRIDGIDN.VAS------tt................................
F0UFF0_AJEC8/147-230             ..............k-PKLLTTLLH..RH.FQN..DKTKIT..KD..AVRALAKYVDIFVREA.LARASY......-ERAEGQSGksasrdtr.................ggararvdnYLEIEDLER.LAP------he................................
F4PWS8_DICFS/15-84               ..............n-PKTVESILR..LA.I-K..DKIKIS..KE..STQLTAAYLEWMIAEC.FKRMTK......QAEIDEASE..................................-IGLEQLEK.IMAQLLMDF..................................
G4UV78_NEUT9/143-219             ...............PSELLTRLLY..EF.FES..DKTKIT..KD..ANEAVARYVDIFVREA.IARSVV......-EREGGNGTtsg............................gggFLEVEDLEK.IAPQLLLDL..................................
A2DLP6_TRIVA/12-80               ..............i-KAIIESALA..DQ.NDD..QKLRIP..PT..TVELIAEYLRCVVVEA.TERAAD......VAGDEK---..................................VIDESHLEK.ILPQLLLDI..................................
G3VAX2_SARHA/9-79                ..............r-KELVNKLLY..LH.FKD..DRCKVS..GD..ALQLMVEMLKIFVQEA.AARAIR......QAQAEDQEK..................................-VDIEQFEK.VLPQLLLDF..................................
H0W6I2_CAVPO/9-79                ..............r-KELVSKLLH..LH.FRD..EKTKVG..GD..ALQLMAELLRIFVVEA.AVRGVR......QAQAEDVTL..................................-VDIDQLEK.VLPQLLLDF..................................
C8Z6E2_YEAS8/3-80                ..............s-KEALIKILS..QN.EGG..NDMKIA..DE..VVPMIQKYLDIFIDEA.VLRSLQsh..kdINGERGDKSp................................lELSHQDLER.IVGLLLMDM..................................
C9SLB7_VERA1/1-57                ..............m----------..--.FAR..EETRMT..EG..ASQAAARYIDVFVREA.IARCVH......-EREGG---..................................FLEVDDLEK.ISAQLLMDF..................................
D2GVE5_AILME/87-145              ...........hlre----------..--.---..-ESSVS..GD..ALWLMAELLTIFVVET.AVRSVR......QAQAEDLAL..................................-VDVDQLEK.VLPQLLLDF..................................
E9E195_METAQ/62-116              ...............PRDLLTRILH..EF.FAK..DSTRIS..RD..ANAAVGKYMDIFVREA.IARAAM......EKN------..................................---------.---------agflevs...........................
A1D1B8_NEOFI/139-219             ...............PPKLLTRLLH..HH.FKS..EKTKIA..KD..ANEVVAKYVDVFVREA.LARAAY......-ERAEGLADrpggi........................sigdgFLEVEDLEK.MAPQLALDF..................................
B9RAQ7_RICCO/39-98               ........vgvgtsk----------..--.-KI..RSTSAN..SN..ALKLSCELLRVFISEA.VQRAAT......IAEAEGVRK..................................-IGA-----.---------dsifrtsni.........................
E9CDC0_CAPO3/10-80               ..............k-PALIEKIFE..QS.WGG..RKLRTA..SD..STRLTAEFMRVFVIEA.MGRAAS......VAKAEGSDT..................................-IEPHHLEA.VLPELLLDF..................................
Q4WRE9_ASPFU/136-216             ...............PPKLLTRLLH..HH.FKS..EKTKIA..KD..ANEVVAKYVDVFVREA.LARAAY......-ERAEGLADrpgei........................sigdgFLEVEDLEK.MAPQLVLDF..................................
G2WC02_YEASK/3-80                ..............s-KEALIKILS..QN.EGG..NDMKIV..DE..VVPMIQKYLDIFIDEA.VLRSLQsh..kdINGERGDKSp................................lELSHQDLER.IVGLLLMDM..................................
Q019W8_OSTTA/19-88               .....edesarartg----------..-V.ERE..FDAGIK..PE..ALEDLATLVEAFIVEA.TARACA......LADIEGSRS..................................-IEGEHIER.VLPQLMLDF..................................
F0ZTX8_DICPU/4-56                ............qpv----------..--.---..----IS..ED..SILLTCDLLDCLINEA.ISRMHQ......IAMDGE--E..................................-LNLSHLEK.ILPQLLLDF..................................
A3GI84_PICST/10-107              .............sv--TTIARIFR.eIG.FKN..ADTSIM..LS..TLKLSAEYIRLFVNEA.IIRANE......ERILEGDSL..................................-SKVDGIDN.V--------esasdanievdaeaedeiiedddiddldpediqd
C1MIX6_MICPC/51-110              ...........graa----------..--.---..RKISIK..DE..AVLASAEVLRHFAAEI.VHRAVE......IAAQDGDDT..................................-VDGGHLER.ILPQLMLDF..................................
Q7XUQ1_ORYSJ/49-111              ............pet----------..-S.RRN..RSATAN..AS..ALKVSCELLRIFVTEA.VQRSAF......IAEAEGTTT..................................-IEPTHLER.VLPQLLLDF..................................
C5MID8_CANTT/9-96                ...............PLKTIARIFK.eLS.FKS..SNTRIT..LS..TLELSSEYIKLFINEA.IIRANE......ERLDEGDSL..................................-VKIDGIDN.VT-------qypnieedqeevnvediedfded...........
C5FBD6_ARTOC/117-203             .............dy--KLVTTILH.eIA.FKK..KKTRIT..KD..AVKLFAKYIESFASEA.VGRSIE......EKRAINTAGietsdir....................teaknnnYLETEDLER.AYPQLMLDF..................................
B0XNW4_ASPFC/136-216             ...............PPKLLTRLLH..HH.FKS..EKTKIA..KD..ANEVVAKYVDVFVREA.LARAAY......-ERAEGLADrpgei........................sigdgFLEVEDLEK.MAPQLVLDF..................................
G2XS27_BOTF4/166-238             ...............PNDLLSKIMH..EL.FAE..PNTRIS..KE..ANKAVGKYMDTFVREA.IARVRY......TERGSGRGG.................................gFWEVEDLEK.MAPQLLLDF..................................
G1XJQ9_ARTOA/34-96               ...............PPELIAKLVK..NF.LED..EGTKVS..GA..ATKTVGEYMHLFLTEA.VYRAVS......NRRD-----..................................---------.---------gdpwakttnsglml....................
H2ZDL5_CIOSA/4-77                ..............s-PEFVTQLLQ..KY.FSD.sDRIKINtnDS..TAKLCADLLTVFVCEA.ATRAAN......QAGNEDSTI..................................-CEVEHLEK.ILPQLLLDF..................................
A7TL11_VANPO/8-87                ...............PKETIARLLE.tSS.FEH..SSTRIT..ED..VVEGLQKYMELFVREA.IMRSIE......TKAKLEEENsft...........................gvrvELTHTDLEE.IAGLLLLDM..................................
I1IYX3_BRADI/47-110              ...........vpet----------..-S.RRT..RSTTAN..AS..ALQVSCELLRMFVTEA.VQRSAV......IAEAEGTTT..................................-IEPTHLER.VLPQLLLDF..................................
A1CNH8_ASPCL/139-223             ...............PPKLLTRLLH..HH.FKS..EKTKLA..KD..ANTVVAKYVDIFVREA.LARAAY......-ERAEGLGGgidgsgg....................rmpigdgFLEVEDLEK.MAPQLALDF..................................
H3GXK2_PHYRM/46-110              .....lvsaaaaasr----------..--.---..-VRKIH..AD..AVKLSAEMLRLFVVEA.FRRAQM......EAMVDDSEK..................................-VEPQHVEQ.ILAQLLLDF..................................
H9J3A8_BOMMO/591-660             ............emd---VIKELLE..NH.FQE..SKTKIA..PH..ALMLLADVAKCLVTET.CLRAVK......QAQREGSNK..................................-VDVEHIEK.CLPQLV---ii................................
C5JYD2_AJEDS/140-227             ...............PPKLLTTLLH..RH.FQD..DKTKIA..KD..AGRVVAKYVDIFVREA.LARAAY......-ERTEGQSSksgsrdas.................grarakvdsYLEVEDLEK.LAPQMVLDF..................................
A8WRA8_CAEBR/6-77                ..............k-QSTVRSILT.vAR.RGK..KRLNLD..SD..ALAVLTALINLLAQET.IARTCQ......TAANTGDRH..................................-VTRDHLKR.IIAQIMLDF..................................
YQEC_SCHPO/9-88                  .............sl--NTLARILT..LY.FSS.eKGTKIT..PS..ALELITQYLRIYSKEA.VCRAYE......EKKNSIMSSsen............................ediVLELEDLENgIAAQLALDF..................................
C4R695_PICPG/7-103               ..............s-KTTLARLFH.tVA.FEE..PDTRIS..SK..TLELSIEYLKIFTKEA.VIRADE......VRRDRNGQVrskyniklenve..........dqpientdsnggILDVNHLSQ.ISGSLILDF..................................
Q2UQY1_ASPOR/130-194             ...............PPKLLTKLVH..HH.FKG..QKTKIA..KD..ANEVVAKYVDVFVREA.LARAAF......-ERAEGGKG..................................-V-------.---------ergvgdgflei.......................
D4B147_ARTBC/121-189             .............dy--KLITTILH.eVA.FKK..KKTRIT..KD..GVKLFTKYIESFATEA.VSRAIE......EKRMNNAAS..................................---------.---------matpatradiehsn....................
Q6BJ85_DEBHA/16-86               ...............PIATIARLFQ.tSA.FKN..EKTRIT..QK..TLQLSSEYIKLFINEA.LIRSNE......ERLAEGDTL..................................-TKVDGIDN.LNKT-----reme..............................
C4JIQ2_UNCRE/121-198             ...............PPKLLAAIIH.rHMkRKG..EKMRIT..KD..ANRLYAKYIDIFVKEA.IARAIY......ERKDKLQTD..................................---------.---------giqrdrtrtmidsylekrelar............
#=GC SS_cons                     ..............--CHHHHHHHC..TT.SSS..TT-EE-..CC..CHHHHHHHHHHHHHHH.HHHHHHHH..HHHHHHTTXSSX................................XEE-HHHHHH.HCHCHHCHT..................................
#=GC seq_cons                    .................chls+lLp...t.Fps..ccT+ls..p-..AlplsucalclFVpEA.ltRust.......tpscsttt...................................l-l-cLE+.lhPQLLLDF..................................
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