GenomeNet

Database: Pfam
Entry: CP_ATPgrasp_1
LinkDB: CP_ATPgrasp_1
Original site: CP_ATPgrasp_1 
#=GF ID   CP_ATPgrasp_1
#=GF AC   PF04174.9
#=GF DE   A circularly permuted ATPgrasp 
#=GF PI   DUF407;
#=GF AU   Kerrison ND, Finn RD,Iyer LM, Abhiman S, Burroughs AM, Aravind L
#=GF SE   COG2308
#=GF GA   100.00 100.00;
#=GF TC   100.40 100.20;
#=GF NC   99.50 99.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   20023723
#=GF RT   Amidoligases with ATP-grasp, glutamine synthetase-like and
#=GF RT   acetyltransferase-like domains: synthesis of novel metabolites
#=GF RT   and peptide modifications of proteins.
#=GF RA   Iyer LM, Abhiman S, Maxwell Burroughs A, Aravind L;
#=GF RL   Mol Biosyst. 2009;5:1636-1660.
#=GF DR   INTERPRO; IPR007302;
#=GF CC   An ATP-grasp family that is present both as catalytically active
#=GF CC    and inactive versions. Contextual analysis suggests that  it
#=GF CC   functions in a distinct peptide synthesis/modification system 
#=GF CC   that additionally contains a transglutaminase, an NTN-hydrolase,
#=GF CC    the Alpha-E domain, and a transglutaminase fused N-terminal to
#=GF CC   a  circularly permuted COOH-NH2 ligase. The inactive forms are
#=GF CC   often  fused N-terminal to the Alpha-E domain [1].
#=GF SQ   57
#=GS A1A098_BIFAA/50-378       AC A1A098.1
#=GS X8AUG3_MYCXE/124-251      AC X8AUG3.1
#=GS B1M6F7_METRJ/100-432      AC B1M6F7.1
#=GS G4MEB0_9BURK/18-200       AC G4MEB0.1
#=GS X7ZI94_MYCXE/103-257      AC X7ZI94.1
#=GS A9H282_GLUDA/91-422       AC A9H282.1
#=GS T1B843_9ZZZZ/70-251       AC T1B843.1
#=GS Q8Y0C3_RALSO/108-439      AC Q8Y0C3.1
#=GS Q7X1F2_9BACT/1-250        AC Q7X1F2.1
#=GS X8ALA0_MYCXE/82-260       AC X8ALA0.1
#=GS K5WIC2_FRATL/83-394       AC K5WIC2.1
#=GS S6Q426_PSESF/72-374       AC S6Q426.1
#=GS B4EHB6_BURCJ/116-451      AC B4EHB6.1
#=GS Q9HUN7_PSEAE/81-412       AC Q9HUN7.1
#=GS K8Y9V0_FRATL/83-394       AC K8Y9V0.1
#=GS Q2K491_RHIEC/98-432       AC Q2K491.1
#=GS S6UQ94_PSESF/1-147        AC S6UQ94.1
#=GS B3E3V9_GEOLS/83-414       AC B3E3V9.1
#=GS X8A4F1_MYCAV/65-297       AC X8A4F1.1
#=GS L8FCJ6_MYCSM/138-466      AC L8FCJ6.1
#=GS A0PPG0_MYCUA/119-447      AC A0PPG0.1
#=GS M5UDS6_FRATL/83-394       AC M5UDS6.1
#=GS B6IMV0_RHOCS/77-408       AC B6IMV0.1
#=GS K5XSJ4_FRATL/83-394       AC K5XSJ4.1
#=GS D0L0C4_HALNC/81-412       AC D0L0C4.1
#=GS X8F632_MYCUL/27-125       AC X8F632.1
#=GS B2ICY7_BEII9/94-428       AC B2ICY7.1
#=GS Q5SDQ9_MYCMR/120-448      AC Q5SDQ9.1
#=GS Q0RH44_FRAAA/80-411       AC Q0RH44.1
#=GS H1QUF7_9ACTO/1-139        AC H1QUF7.1
#=GS Q6N7S9_RHOPA/71-403       AC Q6N7S9.1
#=GS S7SLE8_MYCMR/115-443      AC S7SLE8.1
#=GS X1JEK0_9ZZZZ/94-255       AC X1JEK0.1
#=GS A0A052J3A8_9BORD/75-242   AC A0A052J3A8.1
#=GS W4I308_MYCGS/104-278      AC W4I308.1
#=GS U4V8P9_9RHIZ/70-305       AC U4V8P9.1
#=GS K5YBB6_FRATL/83-394       AC K5YBB6.1
#=GS Q97YL5_SULSO/75-386       AC Q97YL5.1
#=GS X8FE62_MYCUL/119-447      AC X8FE62.1
#=GS S3LLH7_KLEPN/78-273       AC S3LLH7.1
#=GS A0A017FB12_ACIBA/115-335  AC A0A017FB12.1
#=GS A4IYM2_FRATW/86-397       AC A4IYM2.1
#=GS A0QWP7_MYCS2/138-466      AC A0QWP7.1
#=GS S2DSR5_KLEPN/78-249       AC S2DSR5.1
#=GS I7G876_MYCS2/139-467      AC I7G876.1
#=GS L7V997_MYCL1/119-447      AC L7V997.1
#=GS T1CCF3_9ZZZZ/1-286        AC T1CCF3.1
#=GS S6VP97_PSESF/72-376       AC S6VP97.1
#=GS K5Y6H1_FRATL/83-394       AC K5Y6H1.1
#=GS R7CGC7_9ACTN/66-220       AC R7CGC7.1
#=GS Q970N0_SULTO/87-396       AC Q970N0.1
#=GS T0ZF02_9ZZZZ/1-101        AC T0ZF02.1
#=GS Y2411_MYCTU/100-431       AC P9WLA9.1
#=GS F3G839_PSESJ/72-300       AC F3G839.1
#=GS S7R1J9_9MYCO/115-443      AC S7R1J9.1
#=GS B2HNB5_MYCMM/115-443      AC B2HNB5.1
#=GS E2CP30_9RHOB/74-239       AC E2CP30.1
A1A098_BIFAA/50-378                  ...........PRIIESDEFDRMEAGLKQRVNALNAYLRDIY.S.....DK...........QAIKDGIVPEEYVYTSAG.Y.F...P.Q.....V...N...G..........V...T........P...P..G...G........V...............F.....AHIAGEDLVQ...G.Q....D....G....Q....WWVLEDNLRIPSGASYLLFARDIERR.IT.PSLFRNV.....RV.RDN...RDYPRLLRQS........M.....DF................V.............S.T............D............G..................-........-..-............-.......IA...V.VLTPGRYN.SAF..FEHAYLAEKTGAALAFPEDLE.V.V...D.N.K.V.YFL.....D..Y.....AG.R.K...hRVGVVYRRLSD.E..YL..DPFA.FN.PD.SV.I..GVP...GILSAYRSGNVAIVNAPGNGAADDKAIYYFVPNMIRYYLGEEPILHNA........PTYMPMFD..KDRKEVLDRLG....E....LVIKDVAE..AG........GYG.VVFGS......SL...DRSQREELAERIKAEPRRFIAQ.................................................................
X8AUG3_MYCXE/124-251                 .....ptvvss-------------------------------.-.....--...........------------------.-.-...-.-.....-...-...-..........-...-........-...-..-...-........-...............-.....----------...-.-....-....-....-....-------------------------C.TL.PRPLRAI.....RP.RPT...APFAQALRLA........L.....IE................A.............A.P............E............T..................A........E..D............P.......VV...V.VLSPGIHS.ETA..FDQAYLASVLGFPLVESADLV.V.R...D.G.T.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.D..YA..DPLD.LR.SD.SQ.L..GWS...G-----------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------wsrcsa...........................................................
B1M6F7_METRJ/100-432                 ...........PLVIEGPEWAALSAGIVQRAELMEAILADAY.G.....EG...........RLVAEGLLPAAIVAGTPE.F.L...H.P.....L...H...G..........V...A........P...P..G...G........H...............Y.....LKLYAADLGR...G.P....D....G....R....WQVLADRTQAPSGLGWALENRMVLAR.TF.PDFFQDL.....HV.ERL...PAFFQAFRDG........L.....AL................G.............A.E............R............S..................-........-..D............P.......RI...C.LLTSGPYS.STY..VEQAALARYLGLMLVEGDDLV.M.R...D.G.R.L.HVR.....T..V.....SG.L.K....RADALWRRIDA.D..FL..DPLE.LN.PA.SR.L..GVP...GILDALRNGSLVMANMPGAGLVESAALAPYLDGIARRVLGEPLRLGHP........RTWWCGDL..EGLAHARANLD....S....LTLRPAAT..PQr.....gaGRD.AILAG......PV...LAAERERVVAALRDRPFDYVAQ.................................................................
G4MEB0_9BURK/18-200                  ...........PRIIPGDEWRLLEAGLRQRVQALNLFLHDIY.H.....DG...........DIVLAGRIPAEQVYTNAQ.Y.R...P.E.....I...Q...G..........V...D........V...P..L...D........V...............Y.....AHIAGIDVVR...A.G....E...vG....E....FHVLEDNLRVPSGVSYMLENRKMMMR.LF.PELFVQN.....RV.APV...AHYPDLLLET........L.....RS................I.............V.P............E............G..................V........D..D............P.......AV...V.VLTPGMYN.FAY..FEHTFLAQQMGVELVEGKDLF.I.D...D.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
X7ZI94_MYCXE/103-257                 ...........PRVISAAEWARLERGITQRVTALEMYLDDIY.G.....DQ...........EILRDGVIPRRLVTSCEH.F.H...R.Q.....A...A...G..........I...V........P...P..N...G........V...............R.....IHVAGIDLIR...D.Q....R....G....N....FRVLEDNLRSPSGVSYVMENRRTMAR.VF.PNLFATH.....RV.RAV...DDYAAHLLRA........L.....RN................S.............A.A............T............N..................E........A..D............P.......TV...V.VLTPGS--.---..---------------------.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------pt...............................................................
A9H282_GLUDA/91-422                  ...........PRVLTAAEWDHVNRGVQQRVTALNHFLWDIY.H.....ER...........RILRDGIIPADLVLGNAN.Y.R...P.E.....M...E...G..........L...D........V...P..G...G........V...............Y.....VHINGTDLVR...D.G....N....G....T....FLVLEDNARTPSGVSYVIESRHMMLR.VM.PDLAAGL.....DL.MPV...DEYGPRLRHA........L.....AE................V.............A.P............Q............G..................V........A..D............P.......EV...V.LLSPGIYN.SAY..FEHVFLAREMGVPLVEGRDLV.V.E...G.G.R.V.FMR.....T..V.....AG.L.R....PVHSIYRRLND.D..FL..DPRV.FN.PD.SM.L..GVP...GLVDAYRRGNVTIANAIGTGVADDKAVYAYMPRIIRYYLSEEPILSNV........ETHICAEA..EGLAYTLANLE....R....LVVKPVGE..SG........GYG.LIIGP......HA...TKTELEEFRAKLLADPANYISQ.................................................................
T1B843_9ZZZZ/70-251                  ...........PRIVTSTEWRSVELGLTQRVKAIEAFLDDIY.G.....AK...........EILRDRVIPRRLIVGSSQ.Y.S...R.K.....A...A...G..........I...S........G...H..N...Q........V...............R.....ITVAGLDLIR...D.E....T....G....K....LVVLEDNIRTPSGISYVLENRRAMAR.IL.PELFESY.....EI.EPV...GDYPSKLLSA........L.....LD................Q.............A.P............A............G..................V........T..D............P.......LV...V.VLTPGVYN.SAY..FEHSFLARQMGVPLVEGRDLF.C.R...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------g................................................................
Q8Y0C3_RALSO/108-439                 ...........PRIFPAGEWATLERGLRQRVDALNRFLYDIY.H.....AQ...........DIIRAGLIPPDQIYNNAQ.Y.R...P.D.....M...L...G..........V...D........V...P..R...D........I...............Y.....AHVAGIDIVR...A.G....E....G....E....FYVLEDNLRVPSGVSYMLENRKMMMR.LF.PELFARN.....RV.APV...AHYPDLLLDT........L.....RS................V.............S.P............Q............S..................I........S..D............P.......TV...V.VLTPGMYN.SAY..FEHAFLAQQMGVELVEGHDLF.V.K...D.D.H.L.YMR.....T..T.....QG.P.Q....RIDVIYRRVDD.D..FL..DPLV.FR.PD.SQ.L..GAA...GLLSVYRAGNVTICNAIGTGVADDKSIYPYVPDMIRFYLGEAPILNNV........PTYMCRRP..DDLQYVLDHMG....E....LVVKETHG..AG........GYG.MLVGP......AA...TQEEIAAFREVVKARPGQYIAQ.................................................................
Q7X1F2_9BACT/1-250                   ...........-------------------------------.-.....--...........------MIPESQVLRNPL.Y.R...K.E.....L...E...N..........V...T........P...P..G...G........V...............Y.....VHIAGVDIVR...V.S....E....E....V....FYVLEDNLRTPSGASYMLENRSMMMR.LF.PEVFDLM.....NI.APV...DHYPQTLLHT........L.....QD................Lv...........rS.K............D............D..................R........E..S............P.......CT...V.LLTPGVYN.SAY..FEHAFLAEQMGVELVEGQDLF.V.Q...N.D.K.V.YMR.....T..T.....QG.S.Q....RVDIIYRRIDD.D..FL..DPKA.FR.KD.SL.I..GVP...GLADAYRAGNVLLANALGTGVADDKSTYTYVPEMISFYLGEKPLLKNV........DTYCYQKR..MTSSMV-----....-....--------..--........---.-----......--...----------------------lgsy.............................................................
X8ALA0_MYCXE/82-260                  .atrwptvvss-------------------------------.-.....--...........------------------.-.-...-.-.....-...-...-..........-...-........-...-..-...-........-...............-.....----------...-.-....-....-....-....-------------------------C.TL.PRPLRAI.....RP.RPT...APFAQALRLA........L.....IE................A.............A.P............E............T..................A........E..D............P.......VV...V.VLSPGIHS.ETA..FDQAYLASVLGFPLVESADLV.V.R...D.G.T.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.D..YA..DPLD.LR.SD.SQ.L..GVV...GLVEVQRRGAVTVVNTLGSGVLESPGLLRFLPELAEQLLGETRS----........--------..-----------....-....--------..--........---.-----......--...----------------------ctphrcigav.......................................................
K5WIC2_FRATL/83-394                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
S6Q426_PSESF/72-374                  ...........PRSIPASEWRIVERGCIQRVKALNMFLADLY.H.....DQ...........RIIKAGIIPAEQVLANEQ.Y.Q...L.A.....M...Q...G..........L...N........L...H..R...D........L...............Y.....SHVSGVDLVR...D.G....D....G....T....YYVLEDNLRTPSGVSYMLEDRKMMMR.LF.PELFSAQ.....RI.API...DHYPNLLLDT........L.....KS................S.............S.H............L............D..................-........-..N............P.......SV...V.VLTPGRFN.SAF..FEHAFLAREMGVELVEGADLF.V.R...D.D.R.V.FMR.....T..T.....DG.P.K....AVDVIYRRLDD.A..FL..DPLA.FN.PD.SM.L..GVP...GLLAAYRSGNVVLANAIGTGVADDKSVYPYVTDMIRFYLDEEPILKNV........PTWQCRKP..EELSHVLANLG....D....LVVKETQG..SG........GYG.ML---......--...----------------------.................................................................
B4EHB6_BURCJ/116-451                 ...........PLIVTPEDWVVIERGVLQRVRLLNATLADLY.G.....PQ...........TILQRGLLPPALVTGHPG.Y.L...R.A.....M...R...G..........A...R........V...P..G...D........T...............W.....LHVVAFDLAR...G.P....D....G....Q....WRIVAQHTQGAAGLGYLLENRLIVSR.LF.PRGFRGL.....RV.QRL...ASAYRALLQS........M.....QS................L.............S.P............A............A..................-........K..N............S.......RI...V.LLTPGPHS.ATY..FEHAYLARYLGLTLVEGGDLT.A.R...D.N.H.V.FLK.....T..L.....SG.L.E....PVHGILRRVDD.A..WL..DPLE.LR.PD.SM.L..GVP...GLLQAVRAGNVLLANAPGSGFLESPAMLGFMPRLAEGLLGETLTLPAV........HSWWCGEA..AACDDALPQLA....R....GIVKASYP..PDvq...aggAFE.PVIGA......RL...TPAQLAEWRARILARPEHYTVQ.................................................................
Q9HUN7_PSEAE/81-412                  ...........PNLLSAAEWQPIAAGVAQRARLLNALLADLY.G.....DQ...........RLLAEGLLPSELVFGHPN.F.L...W.P.....A...L...G..........I...R........P...P..G...G........I...............F.....LHSYAVDLAR...D.A....D....G....R....WQVLADRTQAPSGAGYALENRQIVSR.AL.PELYRDL.....RV.QHL...AGYFRTLQET........L.....AS................Q.............A.A............G............D..................G........E..T............P.......LV...V.LLTPGRFN.ETY..FEHLYLARQLGFPLVEGHDLT.V.R...D.A.T.L.YLK.....T..L.....GG.L.K....RVHAVLRRLDD.D..FC..DPLE.LR.TD.SA.L..GIP...GLLEAVRQGRVLVANALGSGVLESPGLLGFLPQACRRLLGEELALPSL........DTRWCGEP..QALEAILAALP....D....LVIKPAFP..GQ........RCE.PLFGH......AL...DSAGLASLGERLRERPQAYVAQ.................................................................
K8Y9V0_FRATL/83-394                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
Q2K491_RHIEC/98-432                  ...........PVLIDEREWQALSAGLVQRADLLEAIIADIY.G.....EN...........RLVEEGFLPPALIAANPE.F.Q...R.P.....L...S...G..........I...R........P...A..S...G........H...............Y.....LHFCAFEIGR...G.P....D....G....N....WWVLADRTQAPSGAGFALENRVATTR.AF.SDIYAET.....PV.HRL...ASFFGAFRDA........L.....QD................M.............K.H............S............G..................-........-..D............D.......RI...A.VLTPGPAN.ETY..YEHAYIARYLGFMLLEGEDLA.V.V...K.G.R.V.MVR.....T..V.....AG.L.K....PIGVLWRRLDS.A..FA..DPLE.LN.QN.SH.I..GTP...GLVEALRAESVTIVNALGTGILETRALLAFMPTICRHLLGQDLKLPSI........ATWWCGQK..EEREQVAKNIE....K....MVIGPAYS..RApf...fddNGE.SVLGS......SL...RATAKDSIADWLNSDGPKLVGQ.................................................................
S6UQ94_PSESF/1-147                   ...........-------------------------------.-.....--...........------------------.-.-...-.-.....-...-...-..........-...-........-...-..-...-........-...............-.....----------...-.-....-....-....-....------RTQAPSGAGYALENRQSVAR.AL.PETYRDL.....QV.RHL...SGFFDTLQQT........L.....AR................Q.............A.P............T............S..................S........E..A............P.......LV...V.LLTPGRFN.ESY..FEHLYLARQLGYPLVEGGDLT.V.R...D.A.T.V.YLK.....T..L.....SG.L.R....RVHAIMRRLDD.D..FC..DPLE.LR.TD.SA.L..GVP...GLLEAVRQGNVLV-----------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
B3E3V9_GEOLS/83-414                  ...........PRIITAPEWSRIESGLKQRVKALNLFLEDLY.G.....EQ...........KIIKDGVIPPELIYQGKD.F.R...R.E.....I...V...G..........I...V........P...P..R...G........I...............Y.....THISGIDIIR...D.E....Q....G....D....FLILEDNLRTPSGVSYMIENRVIERR.IL.PEFFNKY.....RV.RRV...EHYPSLLLDA........L.....RC................L.............S.P............R............G..................K........G..T............A.......EI...V.LLTPGIYN.SAY..FEHTFLAKEMGIELAEGRDMV.T.I...N.D.I.V.YLK.....T..T.....KG.L.K....RVDVIYRRIDD.D..YL..DPLI.FR.SD.SS.L..GIA...GVINAWRAGNVAIVNAPGSGIADDKAVYPFVPDIIRYYLGQQPILKNV........PTYQMTNA..TDREYVFDNME....R....MVVKAVSE..SG........GYG.MLMGP......SS...TPALRKEFMDRVLENPRNYIAQ.................................................................
X8A4F1_MYCAV/65-297                  ...........PRVISAAEWARLERGITQRVKALEMYLDDIY.G.....DQ...........EILNDGVIPRRLVTSCEH.F.H...R.Q.....A...M...G..........I...V........P...P..N...G........V...............R.....IHVAGIDLIR...D.E....K....G....N....FRVLEDNLRSPSGVSYVMENRRTMAR.VF.PNLFATH.....RV.RSV...DDYASHLLRA........L.....RN................S.............A.A............T............N..................E........A..D............P.......TV...V.VLTPGVYN.SAY..FEHSLLARQMGVELVEGRDMF.C.R...D.H.Q.V.YMR.....T..T.....EG.E.R....QVDVIYRRIDD.A..FL..DPLQ.FR.AD.SV.L..GVA...GLVNAA------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------apets............................................................
L8FCJ6_MYCSM/138-466                 ...........PMVISAEEWDVLEAGLVQRSRLLDAVLADLY.G.....ER...........RSITSGVLPAQLLFSHPG.Y.L...R.A.....A...H...G..........I...T........V...P..G...R........H...............Q.....LFLHGCDISR...G.D....D....G....A....FVVNADWTQAPSGAGYALADRRVIAH.AV.SELYERI.....AP.RPV...SPWAQALRLA........L.....ID................V.............A.P............E............S..................A........E..E............P.......VV...V.VLSPGIHS.ETA..FDQAYLAGVLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.D..YV..DPLD.LR.PD.SR.L..GVV...GLVEVLRRGAVTVVNSLGSGVLESPGVTRFLPQLAQLLLDETPQLDTA........PLYWGGID..IERSQLLTRLD....S....LLIRPVC-..--........GGE.PIVGP......EL...STAQREELAARIEATPWQWVGQ.................................................................
A0PPG0_MYCUA/119-447                 ...........PLVVSARDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGK.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
M5UDS6_FRATL/83-394                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
B6IMV0_RHOCS/77-408                  ...........PRIISAAEWARLEAGVQQRVKALNLFLHDIY.H.....DQ...........KILKDGIVPADLVLGNHN.F.R...P.Q.....M...I...G..........L...D........V...P..F...G........T...............Y.....IHIMGVDLVR...D.D....A....G....T....FRVLEDNGRVPSGVSYVVENRHMMMR.AF.PDLMSDI.....GI.RPV...DNYGVKLLEA........M.....CE................I.............A.P............A............D..................A........T..D............P.......HV...A.LLSPGPYN.SAY..FEHIFLAREMGVPLVEGRDLV.V.Q...N.D.R.V.YMR.....T..T.....NG.L.E....RVDALYRRVGD.D..FL..DPLA.FN.PD.SC.L..GVP...GIFEAYRKGNVALANAIGTGVADDKAVYAYVPRMIRYYLGEEAIIPNV........ETHICREP..EALKYTLDNLD....R....LVVKPVGE..AG........GYG.ITIGP......MA...SKAELEDCRAKLLADPANYISQ.................................................................
K5XSJ4_FRATL/83-394                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
D0L0C4_HALNC/81-412                  ...........PRVFGANEWRRLELGLKQRVRALNMFLHDIY.H.....DQ...........EIIKAGVIPASQVLGNSM.Y.C...A.A.....M...Q...G..........V...D........L...P..N...Q........V...............Y.....AQIAGIDLVR...V.A....E....N....D....FYVLEDNLRTPSGVSYMLENRNTMMR.LF.PNMFTQR.....TI.QPV...AHYPQILLET........L.....RE................S.............G.P............A............H..................I........E..N............P.......VI...V.VLTPGPYN.SAY..FEHAFLASQMGVELVEGKDLF.V.S...N.N.K.V.YMR.....T..T.....QG.A.Q....QVHVIYRRVDD.D..FL..DPLA.FR.AD.SV.L..GVP...GLFDAYRHGGVSLTNGVGTGIADDKSTYLFVPEMIEFYLGEKPLLSNV........PTWRLDRS..DDLKYVLEHLP....E....LVVKEVQG..SG........GYG.MLVGP......TS...SSKEIEAYRARILENPAGFIAQ.................................................................
X8F632_MYCUL/27-125                  ...........PRVISAAEWSRLERGIIQRVKALEMYLDDIY.G.....DQ...........EILRDGVIPRRLITSCEH.F.H...R.E.....A...M...G..........I...I........T...P..N...G........V...............R.....IHVAGIDLIR...N.E....C....G....D....FRVLEDNLRSPSGC------------.--.-------.....--.---...----------........-.....--................-.............-.-............-............-..................-........-..-............-.......--...-.--------.---..---------------------.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------pts..............................................................
B2ICY7_BEII9/94-428                  ...........PLLIEANEWREIAAGICQRVQLMEAILADVY.G.....EG...........RLVRSGALPATAVTGSPD.F.L...H.P.....L...H...G..........V...R........P...P..G...G........H...............Y.....LYLYAADIGR...G.P....D....G....R....WWVIGDRTQAPSGAGYALANRLVLSR.AF.PTLYREM.....NI.ERL...APFFSAFRDG........L.....MA................M.............A.K............R............Y..................-........-..D............P.......RI...C.LLTPGPFN.ETY..FEQAYLARYLGFLLVEGGDLT.M.R...D.G.E.V.HVR.....T..I.....AG.L.K....RADVLWRRVDS.D..FC..DPLE.LN.GQ.SK.L..GVP...GLIDSLREGGVVVANALGSGVLEAPALMSFMPRLCRTLLNEELALPNI........ATWWCGQP..HEREDVINYMD....G....MAITGAYG..NAvl...grpPHQ.PLVGM......SL...TQEEKDTLAADIRLRGIDYVGQ.................................................................
Q5SDQ9_MYCMR/120-448                 ...........PLVVSAQDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGN.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
Q0RH44_FRAAA/80-411                  ...........PRLLDGDEWDVIERGVTQRVQALEAFLADVY.G.....PA...........EVLADGIVPRRLVLTSAH.F.H...R.A.....A...H...G..........I...D........P...P..N...G........V...............R.....AHVSGIDLIR...D.E....Q....G....G....FRVLEDNVRVPSGVSYVIENRRAMTR.VF.PELFATH.....RV.RPV...ADYATHLLHA........L.....RA................A.............A.P............P............E..................V........A..D............P.......TV...V.VLTPGVYN.SAY..FEHALLARQMGVELVEGRDLT.V.R...D.N.K.V.TMR.....T..T.....EG.E.Q....PVHVVYRRVDD.D..WL..DPLH.FR.PE.SM.V..GCA...GLVNAARGGHVTIANAVGNGVADDKLMYTYVPELIRYYLGEEPILPNV........DTYRLEDP..DQRAHVLDHLD....T....LVVKPVDG..SG........GKG.IVIGP......QA...SDAELAELRVRVSEDPRGWIAQ.................................................................
H1QUF7_9ACTO/1-139                   ...........-------------------------------.-.....--...........--------------TNPH.Y.R...P.E.....M...Q...G..........R...R........P...P..G...D........V...............W.....CHIAGVDLVR...T.G....E....D....G....FYVLEDNVRTPSGVSYMLENREMMMR.LF.PDLFAEH.....AV.RPV...EIYTDMLLRS........L.....QA................S.............A.P............S............G..................A.......gE..D............P.......TI...V.VLTPGPFN.SAY..YEHSFLADKLGVELVEGGDLF.V.N...D.D.T.V.Y--.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
Q6N7S9_RHOPA/71-403                  ...........PRILSAQEWARMELGLKQRVRALNMFLRDIY.H.....GR...........DILRAGVIPDDLIFQNPV.F.R...P.E.....M...N...G..........Q...A........V...P..H...D........V...............Y.....VHIAGIDIVR...V.D....D....E....H....FYVLEDNARTPSGVSYMLENREIMMR.LF.PDLFARH.....RI.APV...ERYPDELLTA........L.....RS................V.............A.P............T............H..................S.......sS..E............P.......TV...A.LMTPGVFN.SAY..YEHSFLADKLGIELVEGRDLV.V.K...N.D.E.V.FMR.....T..T.....EG.L.K....RVDVIYRRVDD.D..FI..DPLT.FR.PD.SV.L..GVP...GLMSAYRAGNVTLANAVGTGIADDKAVYSYMPDIVKFYLDEEPILKNV........PTWRCREP..SDLAYVLDHLS....E....LVVKEVHG..SG........GYG.MLIGP......TA...TKATIEAFREKLKREPEGFIAQ.................................................................
S7SLE8_MYCMR/115-443                 ...........PLVVSAQDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGK.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
X1JEK0_9ZZZZ/94-255                  ...........PLVISSADWDVLESGLVQRSRLLDAVLTDLY.G.....PR...........RSITSGVLPAQLLFAHPG.Y.V...R.A.....A...R...G..........I...E........V...P..G...R........H...............Q.....LFLHGCDISR...G.G....A....G....D....FLVNADWTQAPSGAGYALADRRVIAH.AI.PDLYERI.....GP.RPA...SPWAQALRLA........L.....ID................A.............A.P............E............S..................A........E..E............P.......VV...V.VLSPGIHS.ETA..FDQA-----------------.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
A0A052J3A8_9BORD/75-242              ...........PRIIAAAEWQRLDAGLKQRVRALNRFIHDIY.H.....DH...........DIVRAGIVPAEQVFLNAQ.Y.R...P.E.....M...Q...D..........I...D........V...A..E...D........I...............Y.....CHVAGVDIVR...A.G....A....G....E....FYVLEDNLRVPSGVSYMLENRKMSMR.LM.PDAFGSN.....KV.RPV...AHYPDLLLDN........L.....RE................V.............A.P............G............G..................N........D..D............P.......TV...V.VLTPGMYN.SAY..FEHAFLAQQ------------.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------i................................................................
W4I308_MYCGS/104-278                 ...........PLVVSAADWAVLEAGLVQRSRLLNAVLADLY.G.....AR...........SLLTEGVLPAELVFAHPG.Y.V...R.P.....A...N...G..........I...T........V...P..G...-........H...............Q.....LFLHACDLSR...M.P....D....G....G....YQVNADWTQAPSGAGYALADRRVIAH.AI.PDLYERI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATQLGFPLVES----.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------a................................................................
U4V8P9_9RHIZ/70-305                  ...........PRIISGQEWRRLSQGIEQRVMALNAFLDDIY.H.....RQ...........EIVRAGRIPKELISKNEA.F.L...P.E.....M...I...G..........F...R........P...P..G...G.......nV...............Y.....THIIGVDIVR...T.A....E....N....Q....FYVLEDNARTPSGVSYMLENRETMMQ.LF.PELFQNV.....KV.RPV...ENYPQLLRQS........L.....AS................V.............A.P............P............G..................T........Q..D...........vP.......TV...A.VLTPGIYN.SAY..FEHAFLADQMGVELVEGSDLR.V.V...D.G.R.V.AMR.....T..T.....QG.Y.R....AIDVLYRRVDD.A..FL..DPLT.FR.PD.ST.L..GVA...GIMDALSGG---------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------vgn..............................................................
K5YBB6_FRATL/83-394                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
Q97YL5_SULSO/75-386                  ...........PRIITSELFFKISNYLVARSYVLNKFIREVY.Q.....EG...........----SNPIPDWIVKTTPY.F.R...P.E.....M...M...G..........F...S........P...P..K...D........I...............Y.....IHVYGADIVR...V.N....G....V....-....PFILEDNLRIPSGISYSYKAFEYVDR.FL.PELKEGYd...nRV.LQI...NGL-DYLYDI........L.....RY................V.............S.G............N............K..................-........-..D............P.......II...V.ILTDGNYN.SAY..FEHKFISEKLGIILAEPNDIY.V.K...D.K.E.V.VVR.....T..V....dEG.E.V....HVDVIYRRIEDlD..YL..TP--.--.--.--.-..---...GLMKAYLRGWVTLANAPGTGVADDKATFVWIPYLAEKY-GIKLENVIQ........PYTICLYE.kENLEKVITQPT....R....YVIKKREG..YG........GIG.LAIVK......DD...NINVLKEIYKEYE----NFIAQ.................................................................
X8FE62_MYCUL/119-447                 ...........PLVVSAQDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGK.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
S3LLH7_KLEPN/78-273                  ...........PRIIPAGEWQRIDRGIRQRVKALNAFLYDIY.H.....EQ...........NILRAGLIPAEQVLANEQ.Y.Q...P.C.....M...Q...G..........I...N........L...P..N...N........T...............Y.....AHITGVDMVR...N.N....D....G....Q....YYVLEDNLRTPSGVSYMLENRKMMMR.LY.PEMFEQH.....HI.APV...ERYPSYLLQT........L.....RE................S.............S.L............V............D..................-........-..D............P.......CV...V.VMTPGRFN.SAY..FEHSFLAQQMGVELVESADLF.I.K...N.G.A.V.YMR.....T..T.....EG.P.R....R----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------ggv..............................................................
A0A017FB12_ACIBA/115-335             ...........PRVIEKKQWEKIAAGCAQRVKALNYFLDDIY.H.....GQ...........HILKEQLIPESQIICHEA.F.Q...P.H.....M...L...K..........H...T........L...K..G...K........I...............Y.....SQISGIDIIR...D.S....E....G....E....FFVLEDNLRTPSGVSYMIECRNISQQ.LM.PELCAAN.....NL.QGI...EHYPSLLKEI........L.....QE................N.............S.E............V............D..................-........-..Q............P.......FI...V.VLTPGRFN.SAY..YEHAFLAREMDVPLVTNRDLF.V.E...N.D.Q.V.FVK.....T..I.....RG.R.Q....KVDVIYRRLDD.D..FL..DPLA.FR.PD.SA.L..GVA...G-----------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
A4IYM2_FRATW/86-397                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
A0QWP7_MYCS2/138-466                 ...........PMVISAEEWDVLEAGLVQRSRLLDAVLADLY.G.....ER...........RSITSGVLPAQLLFSHPG.Y.L...R.A.....A...H...G..........I...T........V...P..G...R........H...............Q.....LFLHGCDISR...G.D....D....G....A....FVVNADWTQAPSGAGYALADRRVIAH.AV.SELYERI.....AP.RPV...SPWAQALRLA........L.....ID................V.............A.P............E............S..................A........E..E............P.......VV...V.VLSPGIHS.ETA..FDQAYLAGVLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.D..YV..DPLD.LR.PD.SR.L..GVV...GLVEVLRRGAVTVVNSLGSGVLESPGVTRFLPQLAQLLLDETPQLDTA........PLYWGGID..IERSHLLTRLD....S....LLIRPVC-..--........GGK.PIVGP......EL...STAQREELAARIEATPWQWVGQ.................................................................
S2DSR5_KLEPN/78-249                  ...........PRIIPAGEWQRIDRGIRQRVKALNAFLYDIY.H.....EQ...........NILRAGLIPAEQVLANEQ.Y.Q...P.C.....M...Q...G..........I...N........L...P..N...N........T...............Y.....AHITGVDMVR...N.N....D....G....Q....YYVLEDNLRTPSGVSYMLENRKMMMR.LY.PEMFEQH.....HI.APV...ERYPSYLLQT........L.....RE................S.............S.L............V............D..................-........-..D............P.......CV...V.VMTPGRFN.NAY..FEHSFLAQQMGVELVE-----.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
I7G876_MYCS2/139-467                 ...........PMVISAEEWDVLEAGLVQRSRLLDAVLADLY.G.....ER...........RSITSGVLPAQLLFSHPG.Y.L...R.A.....A...H...G..........I...T........V...P..G...R........H...............Q.....LFLHGCDISR...G.D....D....G....A....FVVNADWTQAPSGAGYALADRRVIAH.AV.SELYERI.....AP.RPV...SPWAQALRLA........L.....ID................V.............A.P............E............S..................A........E..E............P.......VV...V.VLSPGIHS.ETA..FDQAYLAGVLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.D..YV..DPLD.LR.PD.SR.L..GVV...GLVEVLRRGAVTVVNSLGSGVLESPGVTRFLPQLAQLLLDETPQLDTA........PLYWGGID..IERSHLLTRLD....S....LLIRPVC-..--........GGK.PIVGP......EL...STAQREELAARIEATPWQWVGQ.................................................................
L7V997_MYCL1/119-447                 ...........PLVVSAQDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGK.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
T1CCF3_9ZZZZ/1-286                   ...........-----------------------NAFLHDIY.H.....DQ...........EILKAGLIPAGQVLRNSQ.F.R...P.E.....M...V...G..........V...D........V...P..E...Q........I...............Y.....AHIAGIDLVR...A.D....TgnqtG....E....YFVLEDNLRTPSGVSYMLENRKMVMR.LF.PDLFVRQ.....KI.APV...EHYPDLLLSN........L.....RS................V.............A.P............A............G..................I........A..D............P.......TV...V.ILTPGQYN.SAY..FEHAFLAQQMGIELVDGYDLF.V.K...N.K.T.V.FMR.....T..T.....EG.P.R....RVDVIYRRVDD.D..YL..DPQA.FR.KD.SM.L..GVP...GLFSAYKAGNVTLTNAVGTGIADDKAIYVHVPEMIRFYCGEEPILSNV........PTWELRKP..EDLAYVLAHLP....E....LVVKEVHG..SG........GYG.ML---......--...----------------------.................................................................
S6VP97_PSESF/72-376                  ...........PRSIPASEWRIVERGCIQRVKALNMFLADLY.H.....DQ...........RIIKAGIIPAEQVLANEQ.Y.Q...L.A.....M...Q...G..........L...N........L...H..R...D........L...............Y.....SHVSGVDLVR...D.G....D....G....T....YYVLEDNLRTPSGVSYMLEDRKMMMR.LF.PELFSAQ.....RI.API...DHYPNLLLDT........L.....KS................S.............S.H............L............D..................-........-..N............P.......SV...V.VLTPGRFN.SAF..FEHAFLAREMGVELVEGADLF.V.R...D.D.R.V.FMR.....T..T.....DG.P.K....AVDVIYRRLDD.A..FL..DPLA.FN.PD.SM.L..GVP...GLLAAYRSGNVVLANAIGTGVADDKSVYPYVTDMIRFYLDEEPILKNV........PTWQCRKP..EELSHVLANLG....D....LVVKETQG..SG........GYG.MLVG-......--...----------------------.................................................................
K5Y6H1_FRATL/83-394                  ...........PRIISEDEWRELERGLKQRLKALNAFLNDIY.T.....EQ...........KILEDGIIPRELVESSEE.Y.L...P.Q.....M...R...W..........I...K........P...P..H...G........V...............Y.....CHIAGLDLIK...D.E....S....G....-....FMVLEDNVRTPSGVSYVLENRNSLIK.AI.PEAFANT.....NI.KKV...VDYPTELRKA........L.....SS................I.............S.P............T............V..................D.......gK..K............G.......LS...V.VLTPGQYN.SAY..FEHSYLARKMGCELVQGSDLF.V.H...N.N.Y.V.YLK.....T..T.....KG.P.K....LVTVVYRRIDD.K..FL..DPEF.FN.PE.SM.L..GVP...GIIEAYKAGNVVLANAVGNGIADDY-----------------------........--------..-----------....-....--------..--........---.-----......--...----------------------prtvafclndclailkkisyhstgigmesrakveqlikylqdnstetllennhqvityiivslae
R7CGC7_9ACTN/66-220                  ...........PRIIASDEYDELERGLKQRVNALNAFLRDIY.S.....DK...........NIIHDGVIPEEFVYTSPG.Y.L...P.Q.....V...N...G..........V...T........P...P..G...G........V...............F.....AHIAGEDLVQ...G.E....D....G....R....WWVLEDNLRIPSGASYPLFVRDIERR.AD.PKLFRDV.....SL.RDN...RDYPRLLRKT........M.....DF................V.............S.T............E............G..................-........-..-............-.......IA...V.VLSPGRFN.SAF..F--------------------.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------.................................................................
Q970N0_SULTO/87-396                  ...........PRLVSKDFFNKVSRYLIARSYVLNRLIKEVY.E.....EK...........----SSPIPDWIIKTAPY.F.R...P.E.....M...I...G..........F...T........P...P..K...G........I...............Y.....IHVYGADIVR...V.N....S....K....-....PYILEDNLRIPSGIAYAYKSFEYVSR.FI.PELMEGY.....NV.SPI...QGL-EYLHDI........L.....RY................V.............S.G............T............K..................-........-..D............P.......VI...V.LLTDGVYN.SAY..FEHKFISDKLGFILVEPSDLK.I.K...D.G.E.V.VVD.....T..V....dEG.E.I....HVDVIYRRIEDlD..YL..TP--.--.--.--.-..---...SLMKAYLRGWVTIANAPGTGIADDKASFIWIPYLAERY-GVKMDFVIQ........PITLCLYE.kDNLEKVLNYPT....K....YVIKKREG..YG........GIG.LTIVK......DD...NINIIKEILKEYE----NFIAQ.................................................................
T0ZF02_9ZZZZ/1-101                   ..........m-------------------------------.-.....--...........------------------.-.-...-.-.....-...-...-..........-...-........-...-..-...-........-...............-.....----------...-.-....-....-....-....--------------------------.--.-------.....--.---...----------........-.....--................-.............-.-............-............-..................-........-..-............-.......--...-.--------.---..---------------------.-.-...-.-.-.L.YMR.....T..T.....AG.E.E....RVDVVYRRVDD.D..FL..DPLH.FR.PD.SQ.L..GCA...GLLNAARAGNVTIANAVGNGIADDKLTYTYVPALIDYYLGERPILAQP........CRRTGLED..-----------....-....--------..--........---.-----......--...----------------------adqreh...........................................................
Y2411_MYCTU/100-431                  ...........PRVISAPEWTRLERGITQRVKALECYLDDIY.G.....DQ...........EILRDGVIPRRLVTSCEH.F.H...R.Q.....A...V...G..........I...V........P...P..N...G........V...............R.....IHVAGIDLIR...D.H....R....G....D....FRVLEDNLRSPSGVSYVMENRRTMAR.VF.PNLFATH.....RV.RAV...DDYASHLLRA........L.....RN................S.............A.A............T............N..................E........A..D............P.......TV...V.VLTPGVYN.SAY..FEHSLLARQMGVELVEGRDLF.C.R...D.N.Q.V.YMR.....T..T.....EG.E.R....QVDVIYRRIDD.A..FL..DPLQ.FR.AD.SV.L..GVA...GLVNAARAGNVVLSSAIGNGVGDDKLVYTYVPTMIEYYLHEKPLLANV........ETLRCWLD..DEREEVLDRIR....E....LVLKPVEG..SG........GYG.IVFGP......EA...SQAELAAVSQKIRDDPRSWIAQ.................................................................
F3G839_PSESJ/72-300                  ...........PRSIPASEWRVVERGCIQRVKALNMFLADLY.H.....DQ...........RIIKAGIIPAEQVLANEQ.Y.Q...L.A.....M...Q...G..........L...N........L...H..R...D........L...............Y.....SHISGVDLVR...D.G....D....G....T....YYVLEDNLRTPSGVSYMLEDRKMMMR.LF.PELFSAQ.....RI.API...DHYPNLLLDT........L.....KS................S.............S.H............L............D..................-........-..N............P.......SV...V.VLTPGRFN.SAF..FEHAFLAREMGVELVEGADLF.V.R...D.D.R.V.FMR.....T..T.....DG.P.K....AVDVIYRRLDD.A..FL..DPLA.FN.PD.SM.L..GVP...GLLSAYRS----------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------a................................................................
S7R1J9_9MYCO/115-443                 ...........PLVVSAQDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGK.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
B2HNB5_MYCMM/115-443                 ...........PLVVSAQDWEVLEAGLVQRSRLLDAVLADLY.G.....PR...........RLLTEGLLPSELVFGHPA.Y.V...R.G.....A...N...G..........I...E........V...P..G...H........H...............Q.....LFLHGCDISR...I.P....D....G....S....YQVNADWTQAPSGAGYALADRRVVAH.AI.PDLYENI.....AP.RPT...TPFAQALRLA........L.....ID................A.............A.P............D............V..................A........Q..D............P.......VV...V.VLSPGIYS.ETA..FDQAYLATLLGFPLVESADLV.V.R...D.G.K.L.WMR.....S..L.....GT.L.K....RVDVVLRRVDA.A..YA..DPLD.LR.AD.SR.L..GVV...GLVEAQHRGAVTVVNTLGSGILESPGLMRFLPGLAERLLGEEPMLQSA........PMYWGGIA..TERSHLLANLS....S....LLIKSTV-..--........GGN.TRVGP......TL...SSAQLAELAARIEAMPWQWVGQ.................................................................
E2CP30_9RHOB/74-239                  ...........PRILSASEWRRLSAGIDQRVRALNAFLHDIY.H.....RQ...........EIIRAGRIPADLIIQNEA.F.L...P.E.....M...V...G..........F...T........P...A..R...K........V...............Y.....AHIIGTDLVR...V.G....K....D....D....FYVLEDNTRTPSGVSYMMENRETMMR.MF.PELFEIH.....RV.APV...EHYPDSLRQT........L.....ES................V.............G.P............D............Q..................S.......kS..N............Q.......TV...V.VLTPGIYN.SAY..FEHAF----------------.-.-...-.-.-.-.---.....-..-.....--.-.-....-----------.-..--..----.--.--.--.-..---...------------------------------------------------........--------..-----------....-....--------..--........---.-----......--...----------------------wp...............................................................
#=GC seq_cons                        ...........PhllsupEWphlEtGlhQRs+hLsthLsDlY.t.....cp...........cllpsGllPtclVhus.t.Y.h.....t.....h...p...G..........l...p........s...P..t...s........h...............a.....hHltGhDllR...s.s....c....G....p....ahVLEDNhRsPSGsuYhLEsRchhh+.hh.P-Lapsh.....pl.csl...ssasptLhpu........L.....ts................s.............u.P............s............s...........................p..-............P.......hV...V.VLTPGhaN.suY..FEHuaLApphGh.LVEutDLh.V.+...s.s.p.l.ah+.....o..h.....ts...+....tVcVlhRRlDs.s..ah..DPh..hp.s-.Sh.L..GVs...GllpAh+tGsVslsNs.GsGlh-s.............................................................................................................................................................................................
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