GenomeNet

Database: Pfam
Entry: Cas_Csx9
LinkDB: Cas_Csx9
Original site: Cas_Csx9 
#=GF ID   Cas_Csx9
#=GF AC   PF09658.6
#=GF DE   CRISPR-associated protein (Cas_Csx9)
#=GF AU   TIGRFAMs, Coggill P
#=GF SE   TIGRFAMs
#=GF GA   25.00 25.00;
#=GF TC   261.40 260.00;
#=GF NC   20.20 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR013488;
#=GF CC   Clusters of short DNA repeats with nonhomologous spacers, which
#=GF CC   are found at regular intervals in the genomes of
#=GF CC   phylogenetically distinct prokaryotic species, comprise a family
#=GF CC   with recognisable features. This family is known as CRISPR
#=GF CC   (short for Clustered, Regularly Interspaced Short Palindromic
#=GF CC   Repeats). A number of protein families appear only in
#=GF CC   association with these repeats and are designated Cas
#=GF CC   (CRISPR-Associated) proteins. This entry describes archaeal
#=GF CC   proteins encoded in cas gene regions.
#=GF SQ   8
#=GS H3ZK36_THELN/23-399  AC H3ZK36.1
#=GS C7P9K6_METFA/16-391  AC C7P9K6.1
#=GS Q5JGB3_THEKO/23-399  AC Q5JGB3.1
#=GS I3RDT9_9EURY/23-398  AC I3RDT9.1
#=GS Q9UZX2_PYRAB/23-393  AC Q9UZX2.1
#=GS O58615_PYRHO/1-377   AC O58615.1
#=GS F8AED3_PYRYC/23-397  AC F8AED3.1
#=GS D3S4T9_METSF/16-391  AC D3S4T9.1
H3ZK36_THELN/23-399             .........MSWVVMDAGIEPDEEELADALEGALK.SLGSRMK.AHTSKMGRNDRSSFDKVLNAWFGRSAPETYGELFELVVTETIKLLRDGDIDPSESLSSIKIDKNGTYLGVTYNGEQAILPAIIKQPEYYERQSGFLSPTTGQKAQIRMDPLWFSFTALGFFTGFAGFIGGKYYLMTKPGIEGFW..........PYEVEDVIRNGLLQLTGAGASGRISLSTEELYEMKLAMKLAEEGRNVVEEVYPVTLHLISLERQVYTELKTTQLNLAGLSEYMTKYMRKIEAISIGGLPLLVELKEGNATVQKYPLWALLDVAEKELWKGVNGDGEMLAYIFVKDLYRAINSGRRELIRDAVFRLFRQGRALLEG..SSRASG..EFRKVMKTFMWQEHLGVLL.........
C7P9K6_METFA/16-391             lsrimvedf---------DEIDNTTLAEIFKNYVY.GFKEKLKnAGSSKLSRNDKESYKKTYQNWFNTIPPEEYTSLMLDIIEKTINLLEGNKIDAKKSLRAIKVGKNSVDFGIPYNGSYAILPAIIKQVEYYEFLSEFLTPTTGKKSMINLDPIWFSILAIGFLTCFAGYYGGKYYLMLKNDIERYYlaikygmeeeKYELLEIL-EDLEILTDINIQKRFSLEVEEIYELLLSMELAKK--KASGKVFPITLYVIELSGNVYLAKNVLELDLRNSLNFMKKYIDRIKNYSMF--------ESSD---AKIPLEELLYLALKELKNPINEDNENLAYIMVKDLYRAINSGKVEILENTLYLLLRKGHSILSSksSSKSKL..NLEKTFKSFA---------kegniisil
Q5JGB3_THEKO/23-399             .........MSWVVMDAGIEPDEEELADTLEGALK.SLGSRVK.IHTSKMGRNDRSSFDKVLKAWFGRSAPETYGELFELVVTETIKLLRDGNIDPGESLSTIKTDKNGTYLGIAYNGEQAILPAIIKQPEYYERQSGFLSPTTGQKAQIRMDPLWFSFMALGFFTSFAGFIGGKYYLMTKPGIEVFW..........PYEVEEIIEKGILPLTGAGASGRISLSTEELYEMKLAMKLAEEGRDVIEEVYPVTLHLISLEGQVYTELKTTQLNLTGLSEYMEEYVNRIESASMGGLPILVELKAGNATIQKYPLWALVDIAERELWKGVNGDGEMLAYIFVKDLYRAINSGRRELIRDAVFRLFRQGRALLEG..SGRASG..EFRKVMKTFMWQEHLEVLL.........
I3RDT9_9EURY/23-398             ........f-SWIVMEAGLSPSAEDFADIFENSIEnTLKKRAK.MNSSRMGRNDKNSYDKVLSAWYGVKAPDTYIELFELAIKEAVKLLRSKKIDPTKSLGTIKWDNKGTYLGQPYNGHYAISPAVVKQPEYYEFQSDFLKPTAGQKAQIYLDPLWLSLLSLGFLTAFAGFIGGKYYLMTKPSIEVYF..........P-DVEEIL-DGILALTDAGIESKARLDAEELYELKIAMKLAEEGRNVPEKTYPVTLHLISLEGQVYTELKTLQLDIGELSNYLATYIKKIENYMTMGVDLKVKLKEDNIEVEKYPLWALVDIAEKELRSGVNGDGEMLAYILVKDIYRAVNTGRRELIEDSIFRLFRQGRGLLEG..TGKASG..ELRKVLRAFMQEGHLEVLM.........
Q9UZX2_PYRAB/23-393             ........f-SWIVMDAGLSPNPNDFADAIENSMD.TLKKRAM.MNSSRIGKNDRNSYDRVFSKWFGVKAPDTYMELFELVINETIKLLRSGKIDPAKSLQSITRNKNGTYLGQAYNGEYAITPAVIKQPEYYEFQSEFLKPTAGQKAQIYLDPLWFSLLSMGFLTAFAGYIRKRYYLMTKPGIEVYF..........P-DVEEILIDGIIALTDAGISSRARLDAEELYELRIVMKLAEEGRKVPEMTYPIALH-ISLEGQVYTELKTLQLDLKELSNYLATYVKKIENYRVMGVDLKVKLKEGE----KYPLWALVDIAEKELNKGVSGDRELLAYIFVKDLYRAVNSGRKELIEDSIFRLFRQGRGLLEG..EGRASG..ELRKVLRVFMQEDHLEVLI.........
O58615_PYRHO/1-377              .........MSWVVMEAGLEPDKEELIEALEGALN.SLESRTR.INTSKIGRNDRNSFNDVLQAWFNRSTPETYGELFELVIRETIKLLKEDKIDPSASLSTIKTDKNGTYLGVVYKEKQAILPAILKQPEYYEYQSSFLKPTTARKAQIRMDPLWFSFMALGFFTSFAGFISGKYYLITKPGIEGFW..........PYEVEDIIEHGILPLTSAGASGRISLTTEELYEMKLAMKLAEEEKNIIDEVYPVTLHVISLEGQSYTELKTIQLNLIELNNYITEYVKKIRASKVGSMSLLVELKEGGATVKKYPLWALVDIAEKEVWKGVKGDEEMLAYIFVKDLYRAINSGKKDIIQDSIFRLFRQGRALLEG..SSRGSG..EFRKVMRTFMWEEHLGVLL.........
F8AED3_PYRYC/23-397             .........LSWVVIDAGLSPNADDFADALENSMD.TLEKRAR.MNSSRMSRNDRSSYNKLLSAWYGVKAPDTYTELFELAIREAVKLLRSGKLDPAKSLGSIKWDKNGTYLGQPYNGQYAISPAVVKQPEYYEFQSDFLKPTAGQKAQIYLDPLWLAILSTGFLTAFAGFIDGRYYLMTKPGIEAYF..........P-DIEDILD-SLLILTNAGIESRARLETEELYELKITMKLAEEKMNVLEEIYPVTLHLISLEGQVYTELKTLQLDLRELSNYLLAYVERIENYMAMGVNLKVKLKEDNIEVERYPLWALVNIAERELRKGIEGDRELLAYILVKDLYRAVNAGRKELIEDSVFRIFRQGRGLLEG..TGKASG..ELRKVLRAFMQEHHLEVLV.........
D3S4T9_METSF/16-391             ......lsr---IIVEDVDEIDNSTLAEIFKNYVD.SFKEKLKnAGSSKLSRNDKESYTKTYQKWFNINPPEEYVSLMLDIIEKTINLLEDNKIDAKKSLETINVGKNSVNFGIPYNESYAILPAIIKQVEYYEFLSEFLTPTTGKKSMINLDPIWFSILAVGFLTCFAGYYGGKYYLMLKNDIERYYlaikcgleeeKYELLDILED-LEILTDINIQRRFSLEVEEVYELLLSMELAKK--KASGRIFPITLYVIELSGNVYLAKNVIELDLRNSLEFMKKYIDRIKNYFMFD-----------TSDAKAPLEELLNLALSELKNPVNEDNENLAYIMVKDLYRAINSGKVEILENTLYLLLRKGHSIMSS..KSKSKSklNLEKIFKNFA---------kegnvisil
#=GC seq_cons                   ..........SWlVM-AGlEPDs--LADslENulc.oLccRsK.hsSSKhGRNDRsSYcKVLpAWFGhpAPETYsELFELlIcETIKLLRssKIDPuKSLuoIKhDKNGTYLGlsYNGcYAILPAIIKQPEYYEFQS-FLpPTTGQKAQIpLDPLWFSlLAlGFLTuFAGFIGGKYYLMTKPGIEsYa..........PYEVE-ILccGlLhLTsAGIpuRhSL-sEELYELKLuMKLAEEt+sVsEclYPVTLHlISLEGQVYTELKTlQLDLppLSNYhpcYlc+IENYphhGlsLhVcLKEushplpKYPLWALVDIAEKELpKGVNGDsEhLAYIhVKDLYRAINSGR+ELIEDolFRLFRQGRuLLEG..ou+ASG..ELRKVh+sFM.pcHLtVLl.........
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