#=GF ID   Casc1
#=GF AC   PF12366.3
#=GF DE   Cancer susceptibility candidate 1 
#=GF AU   Gavin OL
#=GF SE   Prosite
#=GF GA   21.30 21.30;
#=GF TC   21.80 21.30;
#=GF NC   20.80 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16410263
#=GF RT   A V141L polymorphism of the human LRMP gene is associated with
#=GF RT   survival of lung cancer patients.
#=GF RA   Manenti G, Galbiati F, Pettinicchio A, Spinola M, Piconese S,
#=GF RA   Leoni VP, Conti B, Ravagnani F, Incarbone M, Pastorino U,
#=GF RA   Dragani TA;
#=GF RL   Carcinogenesis. 2006;27:1386-1390.
#=GF DR   INTERPRO; IPR022110;
#=GF CC   This domain family is found in eukaryotes, and is typically
#=GF CC   between 216 and 263 amino acids in length. Casc1 has many SNPs
#=GF CC   associated with cancer susceptibility.
#=GF SQ   204
#=GS B4L9E8_DROMO/214-483    AC B4L9E8.1
#=GS B4PE86_DROYA/732-948    AC B4PE86.1
#=GS H2Q5L9_PANTR/242-460    AC H2Q5L9.1
#=GS F6WC46_MONDO/314-486    AC F6WC46.1
#=GS B4I6M5_DROSE/898-1108   AC B4I6M5.1
#=GS H9JPD0_BOMMO/47-251     AC H9JPD0.1
#=GS Q7QJF4_ANOGA/312-466    AC Q7QJF4.3
#=GS B4L9E8_DROMO/757-973    AC B4L9E8.1
#=GS B3M6V3_DROAN/798-1014   AC B3M6V3.1
#=GS B4GUM0_DROPE/783-999    AC B4GUM0.1
#=GS Q17M71_AEDAE/309-450    AC Q17M71.1
#=GS B4IAI3_DROSE/800-1016   AC B4IAI3.1
#=GS B5DQT5_DROPS/249-515    AC B5DQT5.1
#=GS E1BMU3_BOVIN/236-452    AC E1BMU3.1
#=GS H0V630_CAVPO/301-451    AC H0V630.1
#=GS CASC1_MOUSE/241-469     AC Q6TDU8.1
#=GS B4LB74_DROVI/833-1049   AC B4LB74.1
#=GS E9IZ51_SOLIN/515-688    AC E9IZ51.1
#=GS B4QJL3_DROSI/721-920    AC B4QJL3.1
#=GS G5BEH7_HETGA/130-346    AC G5BEH7.1
#=GS E0W1V7_PEDHC/551-741    AC E0W1V7.1
#=GS B2KFC0_MOUSE/241-469    AC B2KFC0.1
#=GS Q7QJF4_ANOGA/751-952    AC Q7QJF4.3
#=GS CASC1_DANRE/481-679     AC A6H8T2.2
#=GS B3NIU2_DROER/214-474    AC B3NIU2.1
#=GS G1PKM3_MYOLU/236-455    AC G1PKM3.1
#=GS B3M6V2_DROAN/189-429    AC B3M6V2.1
#=GS B4GUM2_DROPE/263-545    AC B4GUM2.1
#=GS A8JUM9_DROME/262-490    AC A8JUM9.1
#=GS B4QJL3_DROSI/198-440    AC B4QJL3.1
#=GS B4PE87_DROYA/1029-1245  AC B4PE87.1
#=GS B4H069_DROPE/379-521    AC B4H069.1
#=GS H2ZH42_CIOSA/237-356    AC H2ZH42.1
#=GS F8W8F9_HUMAN/242-460    AC F8W8F9.1
#=GS B4N3V6_DROWI/856-1072   AC B4N3V6.1
#=GS G1QZH7_NOMLE/242-459    AC G1QZH7.1
#=GS B3NIU1_DROER/253-515    AC B3NIU1.1
#=GS G3R6W7_GORGO/204-422    AC G3R6W7.1
#=GS B3MXV6_DROAN/284-512    AC B3MXV6.1
#=GS Q9VWZ4_DROME/854-1064   AC Q9VWZ4.2
#=GS B3M6V4_DROAN/822-1038   AC B3M6V4.1
#=GS H9K7G0_APIME/369-633    AC H9K7G0.1
#=GS F7AEU0_CIOIN/353-471    AC F7AEU0.2
#=GS G3S5T3_GORGO/237-455    AC G3S5T3.1
#=GS D6WYQ6_TRICA/942-1150   AC D6WYQ6.1
#=GS B4LB73_DROVI/239-523    AC B4LB73.1
#=GS Q7KTX5_DROME/216-476    AC Q7KTX5.1
#=GS B4M6R7_DROVI/295-523    AC B4M6R7.1
#=GS H0XBZ2_OTOGA/236-468    AC H0XBZ2.1
#=GS B4IUJ5_DROYA/198-440    AC B4IUJ5.1
#=GS CASC1_BOVIN/236-452     AC Q29RU8.1
#=GS Q1PQG7_DROMI/18-78      AC Q1PQG7.1
#=GS B4N3V6_DROWI/254-528    AC B4N3V6.1
#=GS B4DNP2_HUMAN/177-395    AC B4DNP2.1
#=GS B4QJL1_DROSI/253-515    AC B4QJL1.1
#=GS B4LB74_DROVI/251-521    AC B4LB74.1
#=GS B7Z095_DROME/250-510    AC B7Z095.1
#=GS B4GUM1_DROPE/219-498    AC B4GUM1.1
#=GS E0W1V5_PEDHC/1-190      AC E0W1V5.1
#=GS G3H3D1_CRIGR/254-483    AC G3H3D1.1
#=GS B5DQT6_DROPS/773-989    AC B5DQT6.1
#=GS F7ET24_ORNAN/1-97       AC F7ET24.1
#=GS B2KFB9_MOUSE/228-456    AC B2KFB9.1
#=GS B0XK85_CULQU/188-390    AC B0XK85.1
#=GS B4E376_HUMAN/124-342    AC B4E376.1
#=GS B3M6V2_DROAN/711-910    AC B3M6V2.1
#=GS B3S5Q5_TRIAD/360-559    AC B3S5Q5.1
#=GS A7RZG1_NEMVE/358-564    AC A7RZG1.1
#=GS F1MDQ9_BOVIN/460-674    AC F1MDQ9.1
#=GS F1R213_DANRE/481-679    AC F1R213.1
#=GS B4GUM2_DROPE/911-1127   AC B4GUM2.1
#=GS B7Z092_DROME/253-515    AC B7Z092.1
#=GS Q9VP91_DROME/64-326     AC Q9VP91.2
#=GS B4J1D2_DROGR/785-1001   AC B4J1D2.1
#=GS B4IUJ4_DROYA/810-1026   AC B4IUJ4.1
#=GS B5DQT5_DROPS/783-999    AC B5DQT5.1
#=GS Q5RDT4_PONAB/93-275     AC Q5RDT4.1
#=GS H3BCR0_LATCH/372-478    AC H3BCR0.1
#=GS B4IUJ3_DROYA/65-327     AC B4IUJ3.1
#=GS F7AEU0_CIOIN/480-681    AC F7AEU0.2
#=GS G6CT66_DANPL/67-269     AC G6CT66.1
#=GS G3VSF6_SARHA/250-477    AC G3VSF6.1
#=GS B3M6V4_DROAN/199-475    AC B3M6V4.1
#=GS E3WWE0_ANODA/335-485    AC E3WWE0.1
#=GS H9IEN6_ATTCE/324-578    AC H9IEN6.1
#=GS AXP83_CIOIN/481-683     AC Q8T880.1
#=GS Q29H75_DROPS/294-522    AC Q29H75.2
#=GS E9IZ51_SOLIN/250-506    AC E9IZ51.1
#=GS Q179I2_AEDAE/817-1020   AC Q179I2.1
#=GS F4WQP1_ACREC/242-497    AC F4WQP1.1
#=GS C3KGM0_DROME/250-510    AC C3KGM0.1
#=GS B4N3V7_DROWI/913-1129   AC B4N3V7.1
#=GS B4R6W8_DROSI/870-1080   AC B4R6W8.1
#=GS F5H555_HUMAN/124-342    AC F5H555.1
#=GS AXP83_CIOIN/356-472     AC Q8T880.1
#=GS H9JPC9_BOMMO/217-376    AC H9JPC9.1
#=GS B3NIU1_DROER/835-1048   AC B3NIU1.1
#=GS B5DQT6_DROPS/219-498    AC B5DQT6.1
#=GS CASC1_MACFA/242-460     AC Q4R796.1
#=GS B5DQI4_DROPS/911-1127   AC B5DQI4.1
#=GS B5RID9_DROME/30-292     AC B5RID9.1
#=GS B4QJL2_DROSI/800-1016   AC B4QJL2.1
#=GS B3MXV6_DROAN/917-1127   AC B3MXV6.1
#=GS B4IAI2_DROSE/253-515    AC B4IAI2.1
#=GS Q1PQG8_DROMI/3-53       AC Q1PQG8.1
#=GS F1P406_CHICK/239-456    AC F1P406.1
#=GS Q9VP91_DROME/650-866    AC Q9VP91.2
#=GS B4PE86_DROYA/198-453    AC B4PE86.1
#=GS Q7KTX4_DROME/257-517    AC Q7KTX4.2
#=GS G1LM06_AILME/242-459    AC G1LM06.1
#=GS F5HMV4_ANOGA/265-504    AC F5HMV4.1
#=GS E1ZWH8_CAMFO/214-470    AC E1ZWH8.1
#=GS B4J1D2_DROGR/244-506    AC B4J1D2.1
#=GS B7Z095_DROME/836-1052   AC B7Z095.1
#=GS E1ZWH8_CAMFO/479-687    AC E1ZWH8.1
#=GS Q17M71_AEDAE/726-911    AC Q17M71.1
#=GS E3WWE0_ANODA/829-946    AC E3WWE0.1
#=GS G1TAN0_RABIT/241-463    AC G1TAN0.1
#=GS B4R6W8_DROSI/249-477    AC B4R6W8.1
#=GS B4IAI3_DROSE/215-475    AC B4IAI3.1
#=GS F1ME26_BOVIN/242-458    AC F1ME26.2
#=GS B4L2A1_DROMO/288-516    AC B4L2A1.1
#=GS B4IAI2_DROSE/839-1055   AC B4IAI2.1
#=GS B4IAI4_DROSE/721-920    AC B4IAI4.1
#=GS B5DQI4_DROPS/263-545    AC B5DQI4.1
#=GS B4NPH6_DROWI/294-522    AC B4NPH6.1
#=GS B3KS92_HUMAN/242-460    AC B3KS92.1
#=GS B4J1D1_DROGR/257-524    AC B4J1D1.1
#=GS B4Q2N1_DROYA/905-1115   AC B4Q2N1.1
#=GS F4WQP1_ACREC/506-713    AC F4WQP1.1
#=GS B0XK85_CULQU/769-971    AC B0XK85.1
#=GS B7Z092_DROME/839-1055   AC B7Z092.1
#=GS B4NPH6_DROWI/913-1123   AC B4NPH6.1
#=GS B4N3V7_DROWI/251-528    AC B4N3V7.1
#=GS B4L2A1_DROMO/888-1098   AC B4L2A1.1
#=GS F7A7N4_MACMU/196-414    AC F7A7N4.1
#=GS B0WSR7_CULQU/751-951    AC B0WSR7.1
#=GS B3NIU2_DROER/808-1024   AC B3NIU2.1
#=GS H9K7G0_APIME/642-854    AC H9K7G0.1
#=GS B4QJL1_DROSI/839-1055   AC B4QJL1.1
#=GS B4LB73_DROVI/906-1122   AC B4LB73.1
#=GS C3Z1T6_BRAFL/34-226     AC C3Z1T6.1
#=GS Q29H75_DROPS/911-1121   AC Q29H75.2
#=GS G1NLQ6_MELGA/239-451    AC G1NLQ6.1
#=GS B3NIU3_DROER/223-483    AC B3NIU3.1
#=GS F6SGF8_MACMU/196-414    AC F6SGF8.1
#=GS H2ZH41_CIOSA/225-439    AC H2ZH41.1
#=GS B4IUJ3_DROYA/788-1004   AC B4IUJ3.1
#=GS B3M6V3_DROAN/215-476    AC B3M6V3.1
#=GS E1NZC6_DROME/1-193      AC E1NZC6.1
#=GS H2ZH40_CIOSA/239-481    AC H2ZH40.1
#=GS H2NJA5_PONAB/1-126      AC H2NJA5.1
#=GS F6W570_HORSE/13-230     AC F6W570.1
#=GS H9FI63_MACMU/1-86       AC H9FI63.1
#=GS B4L9E9_DROMO/665-881    AC B4L9E9.1
#=GS B4DY27_HUMAN/236-454    AC B4DY27.1
#=GS B4PE87_DROYA/442-704    AC B4PE87.1
#=GS E2R895_CANFA/250-456    AC E2R895.1
#=GS G3T9E2_LOXAF/241-463    AC G3T9E2.1
#=GS Q9VWZ4_DROME/233-461    AC Q9VWZ4.2
#=GS F6W570_HORSE/239-452    AC F6W570.1
#=GS B3NT98_DROER/902-1112   AC B3NT98.1
#=GS H2NJA6_PONAB/1-126      AC H2NJA6.1
#=GS B4M6R7_DROVI/889-1099   AC B4M6R7.1
#=GS D2H1A8_AILME/145-362    AC D2H1A8.1
#=GS B4H069_DROPE/910-1120   AC B4H069.1
#=GS B4DX11_HUMAN/72-264     AC B4DX11.1
#=GS F1MDQ9_BOVIN/235-451    AC F1MDQ9.1
#=GS B4QJL2_DROSI/215-475    AC B4QJL2.1
#=GS G1PKM3_MYOLU/464-671    AC G1PKM3.1
#=GS B5MDN1_HUMAN/242-460    AC B5MDN1.3
#=GS B5RID9_DROME/616-724    AC B5RID9.1
#=GS Q7KTX4_DROME/797-1013   AC Q7KTX4.2
#=GS Q7KTX5_DROME/802-1018   AC Q7KTX5.1
#=GS A8JUM9_DROME/883-1093   AC A8JUM9.1
#=GS Q179I2_AEDAE/223-453    AC Q179I2.1
#=GS B4J1D1_DROGR/891-1106   AC B4J1D1.1
#=GS B1H288_RAT/241-469      AC B1H288.1
#=GS B4Q2N1_DROYA/284-512    AC B4Q2N1.1
#=GS C3Z1T5_BRAFL/361-547    AC C3Z1T5.1
#=GS B4L9E9_DROMO/50-321     AC B4L9E9.1
#=GS Q8MRS7_DROME/64-326     AC Q8MRS7.1
#=GS B4IAI4_DROSE/198-440    AC B4IAI4.1
#=GS B4GUM0_DROPE/249-515    AC B4GUM0.1
#=GS F5HMV4_ANOGA/872-1099   AC F5HMV4.1
#=GS Q8MRS7_DROME/650-866    AC Q8MRS7.1
#=GS F1R213_DANRE/240-472    AC F1R213.1
#=GS G1QZI0_NOMLE/299-516    AC G1QZI0.1
#=GS F5H6T6_HUMAN/177-395    AC F5H6T6.1
#=GS B3NIU3_DROER/759-975    AC B3NIU3.1
#=GS B3NT98_DROER/284-512    AC B3NT98.1
#=GS B4PE87_DROYA/250-412    AC B4PE87.1
#=GS G7PK19_MACFA/236-454    AC G7PK19.1
#=GS CASC1_HUMAN/236-454     AC Q6TDU7.2
#=GS H3J7R1_STRPU/490-674    AC H3J7R1.1
#=GS B2KFB8_MOUSE/228-456    AC B2KFB8.1
#=GS B4IUJ4_DROYA/216-476    AC B4IUJ4.1
#=GS H0YJM7_HUMAN/104-291    AC H0YJM7.1
#=GS E2BYG3_HARSA/244-498    AC E2BYG3.1
#=GS E1NZC6_DROME/517-733    AC E1NZC6.1
#=GS F6SGY4_MACMU/236-454    AC F6SGY4.1
#=GS E2BYG3_HARSA/507-716    AC E2BYG3.1
#=GS H9IEN6_ATTCE/587-794    AC H9IEN6.1
#=GS B4GUM1_DROPE/773-989    AC B4GUM1.1
B4L9E8_DROMO/214-483               ........................................................................................r-VQMPLSVLHDCLTLRCIHSNFDNYSQY.AKS......F..DPPIPEGnvd....vnagILD..IE..ECLINEWLMQL..DIQK......ELL.AILL........EK.REIYEEIMR..................VITERTERAA----KEKK........NSDGKETK-IV.I...PK.P........PKEALLVPPGMLPEPYSTFLEREQQQYLDLLDEIyHP.RHLKI.DDDVINLRQHILLGGLYSINFVRRPTDTHY....QTFNVTLHEDGRLLHIKR.EVVadlfnsyrdsr.........fgpratkvmtkrSKMLMDE.Q.KRKT......................HM.LE.DD.E...L.P.....YFFVTIQMAREFCLWGTPIPC....................................................
B4PE86_DROYA/732-948               .........................................................................................WTTKYIKDTVIDRATNRITFKTDRLGLL.GLA......F..KRYEHFP...........---..--..---FRNWSLQP..NEENp....dEII.LCVD........TF.HVRIFFYIT..................-----CKGVRGYVTDLSK........GYTAKPVKYLE.I...VE.P........ISDFRQMRQLFISKNVNIFAENDASFYIENGYFS.-M.KHMAL.--EMHTYNIMALHCKLMKFYRSSWNRLA--....PRRDIIL-----------.GMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVQISENCSDKVNVIVLNY--tn..................................................
H2Q5L9_PANTR/242-460               .......................................................................................gf--EIPRILATSDIAIRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
F6WC46_MONDO/314-486               ....................................................................................liqdn----------------------------.---......-..--HIHMP...........---..--..---YESWELRP..VGDN......EVI.LNVT........TT.FTDIDIHVK..................DSQCMLAAVEVG------........----ENYELSH.L...LK.K........WMNISSLIIAMKQTGLNIFPSEYS----GA-YVAvND.KDPLV.--EMKTYRQMALLASSFSFCWSKWNQAC--....GPQNVIL-KVGELLKKEY.-VEdd............................ewSIYMYNG.E.RAQK......................LK.IN.ES.S...N.T.....F--------------------sg..................................................
B4I6M5_DROSE/898-1108              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................KSGYTVNNFQGGSTQ---........GITDMIGKTLS.L...AE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
H9JPD0_BOMMO/47-251                .........................................................................................WTSNYINDYKFNEDKLTVQFRTGVLWPI.GIA......A..LRYSNLP...........---..--..---YQGWDMRP..DPES.....kGVL.ISVT........GV.SVTMTWLCL..................-----GNSVRL--KWIAN........ATTSALKE---.Y...FD.K........PFSVKRMVQIMREAACDFFPDFDA--YNQVEGSC.-P.KEWSA.--ERHNYHAMAFLSRAYNFQWSRWNAAA--....GRRNIVM-----------.QIR................................EAVDKKReA.KFQL......................LL.VT.SQ.Q...A.S.....ILQANELSQEFS---------cepi................................................
Q7QJF4_ANOGA/312-466               ....................................................................yeepkekktdsdeddqtpqdi----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------------DVDKIYTEHADELMKKERTKK.GA.KTLNL.SEYDVNMRSHRIVAGVYAIDYLEQPMQDVK....IAKKTLL----RTVPQPG.KLKrkkfyqpy................rppptpqpG------.-.---Vrrlpe............eieaeIK.QM.EE.N...LdK.....LALVSVQLPENVFWFEPPIVC....................................................
B4L9E8_DROMO/757-973               .........................................................................................WTTKHIISYKFDKEARSMNIQTDRLGLF.GFA......Y..KRYEHFP...........---..--..---FRDWSLQP..NEENn....dEII.LSVD........TF.HARVILYIS..................-----AAGVRGYVTDISK........NYVAHPVKYLD.I...QT.P........ITDFRELRRRFYEKGINIFAENDACFYIDNGYFS.-V.KHMAT.--EDHTYDAMALHCKLMKFYRSSWNRLA--....SRRNLLI-----------.GMK................................NAKDPTD.Y.TEVT......................MR.IT.PD.N...V.T.....FVEVSELCSDDLDIIKLDF--kn..................................................
B3M6V3_DROAN/798-1014              .........................................................................................WSTKHIKDMKVNMEDNTISFKTDRLGIF.GFS......F..KRYEHFP...........---..--..---FRDWVLQP..NEENp....nEVL.LKLD........TF.HVRTFFYIS..................-----AQGVRGYVTDLSK........GYTAKPVKYLE.I...KE.P........ISDFRVFRKLLIDKNLNIFAANDASYYIDNGYFS.-I.KHVAC.--EEHTYNVMALYCKIMKFYRSSWNRLA--....LRRDILI-----------.NMK................................FVKDTSD.L.SDVT......................VR.IC.PE.G...A.T.....FVKVTEKCSDDVDVVKLTYE-e...................................................
B4GUM0_DROPE/783-999               .........................................................................................WTTKHIVDTTFDRLNHTMTIKTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWSLQP..NEENp....dEII.LQLD........TY.HVRIYLYIT..................-----SKGVRGYATELSN........AYTAKPVKYLE.I...VE.P........VSDFRDLRKIFVEKNINIFAENDACFYIQRDYFS.-I.KHVAT.--EYHTYDVMALHCKLMKFYRSSWNRLA--....SRRDIIV-----------.GMK................................NAKDHSD.L.STVK......................LR.IT.PE.R...T.T.....FVEVQELCSEDINVIKLDF--qe..................................................
Q17M71_AEDAE/309-450               .................................................................................derathdi----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------------DVDKIYTEHADELMKKERAKK.GT.KALNL.FENDVNMRSHRIIAGVYCIDYLEQPMQEVKi.akKSLLRTVPQPGQLTRKKF.-YQpyrppp...................tpqpgvrR--LPEE.I.EAEI......................KQ.ME.EN.L...D.K.....LALITLQLPENVFWFEPPIVC....................................................
B4IAI3_DROSE/800-1016              .........................................................................................WTKEYIMESQIDLETNTLTFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWCLQP..SDDNp....dEVI.LSLD........TY.HVRMFFFIS..................-----ARGVRGYVTDLVK........GYTAKPVKYLD.I...VE.P........ISDFRELRKLLIEKNLNIFAENDANYYITNGYFS.-I.KHIAL.--ELHTYNTMALQCKLMKFYRSSWNRLA--....QRRDIIV-----------.EMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...S.T.....FVKISEMCSDDVNVVKLRYE-e...................................................
B5DQT5_DROPS/249-515               ........................................................................................s-VQMPLSVLRDCLTLRCIHTKFDNYSPN.AKS......Y..ELLVTESpty....ptagIVD..LE..ASAENEWRMQL..EIQK......EVL.EEML........VK.RQLYEELIE.................lINAKNAQAA-----RESK........GADRKA-QKAA.I...PK.F........PKEQPIVPPGMVPDIYEEFVKREKTQYQSFLEEVyHP.NALNL.TYDEINLRECIMLGGIYSIMFVGRPAQTQF....EKFNIILHEDGRALLTMP.EVVavldkp....................edslraS------.-.---Afsaarssnf....rltledignMR.LD.PD.E...L.P.....YFIVVLELAPELCLWGEPKVC....................................................
E1BMU3_BOVIN/236-452               .......................................................................................gf--EIPRILATSDIALRLLHTHYDHVTPL.SPV......L..TPSQEHI...........---..--..---SIVTDFVK..EEVKs...vqTAV.SKDL........QE.ENKQENESNs................vH--EEETKAEG-QGDVEE........QMCPVQ-EEPE.A...TK.Y........EMEMKLLSETVSAAQELLLENASE----------.--.KPYFL.EENEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDL.EA.EN.V...F.P.....PIEVTLEVHENVIFFENPMV-a...................................................
H0V630_CAVPO/301-451               ...........................................................................sergsvfiqegeik----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................---------AEEQSNTEV........QMTSATE-ESK.V...TE.G........ELEMKLLSESVAQAQLDLIKNVPE----------.KP.ETPEY.--KEVDLCHFMILGGVYHLDILELPPQCKP....VKGWIMV-----------.---................................EILKEGL.Q.KFTYppe................itdDL.EA.EN.A...F.P.....PIEVTLQVQEKVTFFEEPLV-a...................................................
CASC1_MOUSE/241-469                .......................................................................................gf--EIPRILATSNVALRLLHTRYDHITPLfPIA......V..TEQNQNPvg.......aeQVN..VE..ESTEKAMTEEK..LFTE.....eKAA.NEDE........QP.KAEQERELN..................LVQEENKYEAIENTVLQR........TSDSE-GEDSQ.T...TQ.L........ELEMKLLSEAVLAAQLCLVENVVE---------L.-P.EASQA.--YKVDLCHFSTLGGVYHLDVLELPPQCKP....VKGWVLV-----------.---................................EILQEGL.Q.RFIYpp.................dttEE.PD.PDvT...F.P.....PIEVTLEIHKSVIFFERPRV-v...................................................
B4LB74_DROVI/833-1049              .........................................................................................WSTRHIMSSQFDRQARTMHIKTDRLGIF.GLA......Y..KRYEHFP...........---..--..---FRDWSMQP..NEENn....eEII.LSVD........TF.HARVILYIT..................-----AQGIRGYVTDITK........NYVAHPVKYLD.I...PN.P........ISDIRELRRRFYEKSINIFAENDACFYIDNGYFS.-V.KHVAT.--EDHTYDAMALHCKLMKFYRSSWNRLA--....SRRNILM-----------.GMK................................NAKDNSD.Y.TEVT......................MR.IT.PD.S...V.S.....FVEVSELCSDNLDVIRLDF--kn..................................................
E9IZ51_SOLIN/515-688               .........................................................................................WSTQDVHDIKYNEEKQTIMFRTGRLGVH.GLA......T..FKFINIP...........---..--..---FQSWELKP..EIGRna..rgGIV.LNVT........AA.IVQAEFIVR..................EDLVCLNSL--------V........GGTSTELK--K.I...IG.E........YMKLHILIEKMRDVGCDLFPERDAFAYVKALS--.-V.KHPVT.--ERHLRECMALLCTAYTFSWSRWNASR--....NFREIVI-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------qfkelhg.............................................
B4QJL3_DROSI/721-920               .........................................................................................WTTKYVKDTVIDRETNRITFKTDRLGLL.GLA......F..KR----P...........---..--..-----------..---D......EII.LSVD........TF.HVRIFFYIT..................-----CKGVRGYVTDLSK........GYTAKPIKYLE.I...VE.P........ISDFRQMRQIFISKNINIFAENDASFYIENGYFS.-M.KHVAL.--EMHTYNIMALHCKLMKFYRSSWNRLA--....DRRDIIL-----------.GMK................................IAKDNSD.Y.SEVT......................VR.IT.PE.K...T.T.....FVQISENCSDKVNVIVLSY--ts..................................................
G5BEH7_HETGA/130-346               .......................................................................................kk---NPRILATSDIALRLLHTHYDHVTPP.QAA......P..APSPQHT...........---..--..---SAASELFK..SETK......STT.EAAS........QE.AQEDSKPQErg..............svFIQEGEIKV-DEQVDSEV........QMTSVK-KESK.A...TE.C........ELEMKLLSETVAAAQLNLIKNAPE----------.--.-KPEVsESKEVDLCQFTILGGVYHLDILELPPQCKP....VKGWMMV-----------.---................................EILKEGL.Q.KFTYppe................iteNF.ET.EN.A...F.P.....PIEVTLQVQEKVAFFEEPMV-a...................................................
E0W1V7_PEDHC/551-741               ..................................................................................tnyeddg----------------TITFNCGRLGLF.GFH......V..TRYKNMP...........---..--..---YEDWLFES..DNDN......GVN.FYLK........TS.MVELNFIIR..................K-----NKVCLEQIR---........-NAPNKVIWSS.I...VG.N........FYTPDDLAKYLKKKGLDIFPQPDAGTYVDT---I.KS.KHYVV.--EKTIYQIWGLFSQSFRFKRSKFNQSA--....GRSNILF-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------laqevnpnhqcdysliqnsmcssyvlkmkedtstsy................
B2KFC0_MOUSE/241-469               .......................................................................................gf--EIPRILATSNVALRLLHTRYDHITPLfPIA......V..TEQNQNPvg.......aeQVN..VE..ESTEKAMTEEK..LFTE.....eKAA.NEDE........QP.KAEQERELN..................LVQEENKYEAIENTVLQR........TSDSE-GEDSQ.T...TQ.L........ELEMKLLSEAVLAAQQRLVENVVE---------L.-P.EASQA.--YKVDLCHFSTLGGVYHLDVLELPPQCKP....VKGWVLV-----------.---................................EILQEGL.Q.RFIYpp.................dttEE.PD.PDvT...F.P.....PIEVTLEIHKSVIFFERPRV-v...................................................
Q7QJF4_ANOGA/751-952               .........................................................................................WSTRDVHDVKFNEDKLTIQFRVGRLGSF.AFA......A..NRYSNVP...........---..--..---YQSWELKP..DIKNp....gTVT.FSLT........AS.VVSTEMTIT..................-----EAGFRVN--SLQG........GPTQ---ALQE.I...LG.L........TMSLRKLIKTLRLAAVDLFPEDDAFNYTEG--TC.-E.KNPIM.--ESHLYDCIGLLALTHNFSWSRWNLLS--....GCRMCVL-----------.LMR...............................eIVEHRRL.P.NHST......................LL.VT.PL.K...A.S.....VIDT-----------------vevspvfn............................................
CASC1_DANRE/481-679                .......................................................................................wr--TDCISETSYDAELRTISFQMTAFYAF.TLL......Q..ETYANMP...........---..--..---FQSWELRP..LGQD......SAL.FTIT........GA.LIEVSITVK..................-------GKQCMLHT---........-EETKDLDR--.L...LG.K........WMSPSELQKAMRKAGINIFVNE----YSDKYVSI.NL.KDPLI.--EHAVYEQMALMSSAVAFSWSRWNAQC--....RQEHLVL-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------qaceqlevgpvaekawslyllgaqrnqhlkmkeqedsfsp............
B3NIU2_DROER/214-474               .........................................................................................KVQVPLSALWDCVTIRCVHTSFDHHSPQ.AKS......Y..EPSTVNSafm....pnagLTD..ME..ESVVGEWLMQT..DIQE......ETL.SNMN........RR.REEYEELMQ..................LIAERTEQAAKEEKFGKG........GDGDKRPK-IV.I...PK.V........PKTVPIVPPGMYPEIFNEFLFREEDQYKKFLKTYfHP.DNLSL.TSEEINLRECIIVGGVYNISFVRRPDQTQF....EKFNIVLHEKGRVLEIIP.QVVa.............................knDARKSRV.T.EYTRmtl...............gnsqMK.LE.DD.E...L.P.....FFVVTLQLPPDLCRWGKPEVC....................................................
G1PKM3_MYOLU/236-455               .......................................................................................gf--EIPRILASSDIALRLLHTRYDHVTPL.RPV......P..IILNDHT...........---..--..---PLESPSVQ..DEVSve..qsAIS.KELQ........EE.YKQPENESN..................-------LVQEEETK-SE........EQDDDTV-GVH.A...SF.V........EEEPESTKQDLEMKILNERVPTAQ---LSLLENA.-P.ERLRAfEDEEVDICQFSTLGGVYHLDILELPPQCKP....MKGWMIM-----------.---................................EILQDGL.Q.KFVYppa................tteDL.ET.EN.V...F.P.....PIEVMLEVHENVIFFENPLV-a...................................................
B3M6V2_DROAN/189-429               .................................................................................imhmqsay---------------MIIHTEFDNFSQN.AKS......F..EPPIMSStny....pnagILD..MQ..ESMINEWIMQQ..DLQE......ETL.AEML........HR.REEYEEVMAdi..............aiRVEQAAKEA-------KS........GNEGKGPK-II.I...PK.A........PREPPLVPPNMFPDIYNDFLRIEDSQNTAF----.--.----L.--DEINLRECIIQGGIYSIMFVRRPDQTEF....NKFNIVWHEDDRLLHTMP.ELV...............................aETKRNHH.A.TEMMrrsrat..........lvtpanAK.LE.DS.D...L.P.....FFHVSIQLPPDLCKWSEPEVC....................................................
B4GUM2_DROPE/263-545               ........................................................................................h-IQLPFSVLCDNMTVRCVHTFFDPYSER.SKS......F..EMVIDSDslp.....hagLLD..IE..DSVIDEWLTQV..DIQD......EII.TKME........SA.MQQYEDIRA..................N-IEAIQPTRKS----KK........DVKTKGQQQGK.P...MK.A........PKEPQALPEGMFPDPYKIFIDREQQEYLNFMDQSyNPaKNPSI.-PGEINLRRFILIGGIFAVDFVRKPKHTAF....EKLNITLHEDGRILYVDRnRLVdeadevglfssrshhgtireapsrltaapsrhE------.-.---Vksaplee........ttedgtiLY.LG.KN.E...L.P.....FFFLTFDLPRHLCRWGNPTVC....................................................
A8JUM9_DROME/262-490               qislpptvhlqssalrglwlnydhfsdycssyclkharsananilrqtkrewrkrkeilqamlddcgreiplseleqltqdqhsassqp----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------PRERTYDVDKLYAEYEDELSKAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ...lN-ARSFI----RTITSA-.---................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
B4QJL3_DROSI/198-440               .............................................................................yrvlsmqdaymd-----------------LHMDFDNISQN.AKS......F..ETAVKASvny....pnagIVD..IE..NSVINEWHMQL..EIQE......ETL.NLML........SR.RREYEDMMEli..............aeKTEQAAKAA-------KQ........TDPDKAVK-II.I...PK.A........PKEPPFVATGMYPDTYDDFLRIEESQYSGY----.--.----L.--DEINLRDYIMLGGIYSIMFIRRPDQTQF....EKFNIVLHEDGRVVHILT.EMKadipve...................avrksniGRKTRET.Y.RGTK......................IK.LE.DD.E...L.P.....YFIVTLQVAADLCKWSEPLVC....................................................
B4PE87_DROYA/1029-1245             .........................................................................................WTTEFILESSFDRESKVLLVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FSHWELER..NEQNp....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYIARPFKYIN.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHVYDAIAVHIKLMKFSRSQWNRLA--....RDRDILL-----------.CLR................................NTRDVHD.G.SEVT......................VR.VT.PE.V...S.T.....FVEVSELCSDDSKVIKLQF--ks..................................................
B4H069_DROPE/379-521               .................................................................................sqpprert----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........------------YDVDKLYAEYEDELSRAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ....LNAHSFI----RTITCA-.---................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.ES.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
H2ZH42_CIOSA/237-356               ..............................................................................vtvdedelddi----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.----L.DPDVVDLRQFSPLGGVFHVDLVKTPPQPNV....VRGWTLT----QILDKPLtAVKypsdnpn..................vgksasrV------.-.---Asanpegr........eeqgspsKT.PL.EQ.Q...Q.P.....PIGLTFTLPQDVMFFEEPQV-a...................................................
F8W8F9_HUMAN/242-460               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B4N3V6_DROWI/856-1072              .........................................................................................WTTKYILESHFNREEATITLKTDRLGIF.GLA......F..KRYEHFP...........---..--..---FKDWYMQP..SEENp....eEIM.LRVD........TF.HVRVILYIS..................-----GLGIRGYVTDQSK........AYVTKPKKYLE.I...IE.P........ISDFQELRQRFWEKNINIFAEHDASFYIDNGYFT.-I.KHVAI.--EDHTYDAMALHCKLIKFFRSNWNRLA--....SRRNILL-----------.CMK................................NAKDNTE.Y.SEVT......................VR.IT.PD.N...A.T.....FVEVSELCSSDLNVFKLDYK-p...................................................
G1QZH7_NOMLE/242-459               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HLV......S..TPSKEHT...........---..--..---SAVTELVK..DIKNv....eKAIsKEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVLAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................taeDF.ET.EN.A...F.P.....PIEVTLEVHENLIFFADPMVV....................................................
B3NIU1_DROER/253-515               ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELAIDSFssp.....ncgLVD..IG..DSVMSEWMAQM..DIQE......DLV.AQME........SE.MRAYNEAIS..................----------FIADAKAK........EQKKHHKAKIK.I...PS.P........PKMPQELPDGMFPDPLKIFLAHEKRDCSDFFNRYfHP.DNINL.LPSEVSLRRFIIIGGIISLVFVRKAKHTAF....EKFNITLHEDGRLLRKSVnILDvsker......................essrsS------.-.---Tkwgigadmkr.stvveeapevpLH.LA.PN.E...L.P.....YYFLSFKVPNHLCLWGEPIVC....................................................
G3R6W7_GORGO/204-422               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SAVTELVE..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEGEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B3MXV6_DROAN/284-512               ......................................................................................qis---LPPTVHLQSSALRGLWLNYDHFSDY.CAS......Y..NLKHARS...........---..AN..ANILRQTKREW..RKRK......EIL.QAML........DE.CGREIPLSE..................-----LEQ-------LTQ........DQHSASSQ---.-...--.P........-------PKEKTYDVDKLYAEYEDELSKAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ...lNARSFIR-----TITSA-.---................................NSLIHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
Q9VWZ4_DROME/854-1064              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................KSGYTVNNFQGGSTQ---........GITDMIGKTLS.L...SE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
B3M6V4_DROAN/822-1038              .........................................................................................WTTEYILESNFDYELKVLTVKTDRLGDF.GFA......Y..PRYIHFP...........---..--..---FRNWELDQ..NELNp....dELI.FTVD........TQ.FVRVVFFIS..................-----NKGIRGYVIDIPK........EYVANPLKYLE.I...TE.P........IVDFVELRKRFQDMNLNVFAELDASCYIDQGYFS.-I.KHLAA.--ELHVYDIMSIHCKLMKFYRSDWNRLA--....TNRDLIL-----------.RLR................................NPKDMHD.A.SEVT......................AR.VT.PE.S...A.T.....FVEVSEVCTENVDVIKLSYQ-s...................................................
H9K7G0_APIME/369-633               .......................................................................................ri--KMPSDMDCHCMAIRGLWLAYDHYSIG.SNS......Y..WMSKLPE...........IVD..LW..NPTLGLFEYSI..KEYD......EKI.RIGEeq....aeGR.RLRLEEKKAilekl.......eypsvpRIDKRKR-ARKPKKSSPK........DHQTEFES-ML.T...SI.L........PSKLSELLP-YLPTPNEIILEKEE----KAMSESkKL.LFTRC.EKTEVNLRKYRILGGIFRVDILYQPPQPKDl.gkDTYLTTL----EL-----.--Pkepkfmsfyk............pyetpqsdpdSER----.-.---Tpei...............ieaeMKaLE.EA.M...D.A.....LVLLTLKLPDSIFWFEPPV--ia..................................................
F7AEU0_CIOIN/353-471               ..............................................................................qieieedeeei----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.----L.DPDVVDLRQFSPLGGVYHVDLLKTPPQPNI....VRGWTLT----QIIDKPLsTVKypsdn.....................pntgrsS------.-.SRVAsanpeg.........rdegspsKT.PL.EQ.Q...Q.P.....PIGLTFALPSNVMFFEEPQV-a...................................................
G3S5T3_GORGO/237-455               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SAVTELVE..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEGEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
D6WYQ6_TRICA/942-1150              .........................................................................................WTKSEVHDLKHNEEKGQLTFRTRKGGTF.ALA......V..YRYANLP...........---..--..---YQAWEIRP..EANG......TIS.VQIT........AA.ILMVEFNVK..................D----------GLIALSQ........LQNSPNNALQD.I...VG.T........YFPLPKLVRMLQSAGVDVFPAFDAFCYIEN--TC.-E.KHWPM.--EKHLYFDMALLSVCFNFAWSRWNMAA--....GRRGIVL-----------.QMRe..............................yNVEKTKQ.K.NHSM......................LH.VT.PL.T...A.M.....FVDCTEVSQTFT---------eegienmk............................................
B4LB73_DROVI/239-523               .........................................................................................KIQIPMSVLGDNLTLRCIHTFFDPYSES.AKS......Y..EQVIDRVtdn....fnggMMD..IE..DCLINEWLMQV..NIME......NAI.TQVE........TK.LIEYEEYLR..................EMELRAAASKTKETDKNK........NKNKRSSKQVTpK...IK.V........LKEPEQLPEGMFPDPRNAFLEQEQREFEEFLDEFlNP.ANMHL.KPYEINLRRYCILGGLYSMIFVQKPKHTDF....QKFNVTLHEDGRILRTLE.ELRadvdedgeegn.........ymagsraasvrfT------.-.---Stsshkirmn...laqedptteqFQ.LN.AD.E...L.P.....YFCMTFKLPEHLCRFGQPLAC....................................................
Q7KTX5_DROME/216-476               .........................................................................................KVQVPLSVLCDCITIRCVHTDFDHHSPH.AKS......Y..EPLTVESifm....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NNMN........RR.REEYDELMQli..............aeRTEQAAKEAKFG----KG........GDGDKRPK-IV.I...PK.T........PKTVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYfHP.DNLSL.TPEEVNLRECIIVGGIYNISFVRRPDQTQF....EKFNIVLHEDGRVLKVIP.QVV................................AKQDNRK.S.RLTEytrmt............lgtsqMK.LS.EE.E...L.P.....FFVVTVQLPPHLCRWGKPEVC....................................................
B4M6R7_DROVI/295-523               .....................................................................................nisl----PPTVRLQSSALRGLWLNYDHFSDY.CSS......F..QLRHARS...........---..QN..ATILRQTKREW..RKRK......EIL.QSML........DE.CAREIPLSE..................-----LEQ-------LTQ........EQHSASSQ---.-...-Q.-........-------PRERSYDVDKLYAQYEDELNKARRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQl.naR---SFI----R---TI-.TVA................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPIAC....................................................
H0XBZ2_OTOGA/236-468               .......................................................................................gf--EIPRILAASDIALRVLHTHYDHVSPL.RHI......P..KPTEEEPttleteilkeeLED..VE..TAIS--TEDQK..ESKP.....eESG.SKLI........HE.-EEIKEQSS..................PEASVCLDLTVCCIRHAA........HMSNFADEESE.A...VK.G........ELEMKLFSETVSAAHLLQIENAPE---------M.--.-PLAF.EDNEVDICQFTTLGGIYHLDILELPPQCKP....AKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDL.EA.EN.A...F.P.....PVEVTLRVHDNVMFFEDPMVV....................................................
B4IUJ5_DROYA/198-440               .............................................................................yrvlrlqdaymd-----------------LHTDFDNISQN.AKS......F..DTPVAASvny....psagLVD..IE..ESVVNEWHMQH..AIQE......ETL.SLML........AR.RREYEDMMQii..............aeKTEQAAKAA-------KQ........TDPDKAVK-IL.I...PK.A........PKEPPEVPTGMFPDIYEDFLRMEDSQYLGY----.--.----L.--DEINLREHIILGGIYSIMFIRRPDQTQF....EKFNIVLHEDGRVVHILT.EMKadikee...................tlrsskiARKTRET.-.---Yrg..................tkIK.LE.DD.E...L.P.....YFIVTLQVAADLCKWSEPVVC....................................................
CASC1_BOVIN/236-452                .......................................................................................gf--EIPRILATSDIALRLLHTHYDHVTPL.SPV......L..TPSQEHI...........---..--..---SIVTDFVK..EEVKs...vqTAV.SKDL........QE.ENKQENESNs................vH--EEETKAEG-QGDVEE........QMCPVQ-EEPE.A...TK.Y........EMEMKLLSETVSAAQELLLENASE----------.--.KPYFL.EENEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDL.EA.EN.V...F.P.....PIEVTLEVHENVIFFENPMV-a...................................................
Q1PQG7_DROMI/18-78                 ...................................................................frrtqisqsrkqtpvgsrirlt----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.-----.------------------------------....------------------.---................................-------.-.---Talea..............rqsnIR.LQ.DN.E...L.P.....YFIVTIQLPQGLCKWSEPLVC....................................................
B4N3V6_DROWI/254-528               ........................................................................................r-VQMPLSVLNDRLTVRCIHTKFDMLTQN.AKS......Y..ERVTLQSvsh....lnagILN..IE..DCLINEWYMQL..DIQQ......ELV.DRMR........SK.WDQYEEAME.................mISNKMEKAA-----KEQR........RSRDKPVKHIN.I...PK.P........PKQPPQLLEGMLPDPHKMFLEREESQYVDFLDELyHP.KRMNL.TSDEINLRQNIMLGGIYSIMFVRRPQHRHF....ERFNITLHEDGRILYTMT.NVVadlee.....................hekslnSTRDSKR.S.GERRlsntqlrl......ngveeyssYH.LD.EK.E...L.P.....YFYVTFKISPDLCYWSEPKVC....................................................
B4DNP2_HUMAN/177-395               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B4QJL1_DROSI/253-515               ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSvip.....ncgLVD..IA..DSVMSEWMSQM..DIQE......DLM.VKME........SE.MRAYNEAIS..................F----------IAEAQAK........EKRKPQKKKVA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNMNL.LPSEVNLRRFIIIGGIVSLVFVRKAKHSSY....EKFNITLHEDGRVLPKSL.NILdesst.....................eessvqP------.-.---Tkldigtdimr.dteageaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPVVC....................................................
B4LB74_DROVI/251-521               ........................................................................................s-VQMPLSVLHDCLTLRCIHTKFDNYSQY.AKS......F..DPCLPDGnvd....vnagIVD..IE..ECLANEWYMQL..DIQT......EML.LSLL........EK.REAYDEALRi................iA--EKTEK----SNKEKK........NNEGNGTK-IV.I...PK.A........PKEALQVPPSMLPDAYSTFLEREQQQYMDMLDEIyNP.ANLKL.ALDEINLRQYIMMGGLYSLMFIRRPMNTHY....QKLNIILHEDGRVLHIMD.DIVanlhrdddsr...........pgsrtsrlserR------.-.---Sklrlnm.........ddnqrrtFM.LE.DD.E...L.P.....YFFVIIHMPRELCLWGEPIAC....................................................
B7Z095_DROME/250-510               .........................................................................................KVQVPLSVLCDCITIRCVHTDFDHHSPH.AKS......Y..EPLTVESifm....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NNMN........RR.REEYDELMQli..............aeRTEQAAKEAKFG----KG........GDGDKRPK-IV.I...PK.T........PKTVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYfHP.DNLSL.TPEEVNLRECIIVGGIYNISFVRRPDQTQF....EKFNIVLHEDGRVLKVIP.QVV................................AKQDNRK.S.RLTEytrmt............lgtsqMK.LS.EE.E...L.P.....FFVVTVQLPPHLCRWGKPEVC....................................................
B4GUM1_DROPE/219-498               ........................................................................................m-VQMPLSVLMDCLTLRCVHTSFDNYSQN.AKS......Y..EQAIPECdsy....pnagIAD..IQ..QSLMSEWHVQL..EMQE......MAL.AAMV........RR.REQYLELLQ..................LIEERTEQASKRGKE--Q........AQGKNKLPKIV.V...PK.T........PKLAPPVPEGMLPDIREAFYQREESDYKEYLNEIyHP.QKLNM.TADEINLRQHIMLGGIYSIMFVRRPMQMQF....QKFNVVLHEDGRILHTMP.DVVaemgggcampe..........frrtqisqsrkQ------.-.---Tpvgsrirlt....talearqsnIR.LQ.DN.E...L.P.....YFIVTIQLPQGLCKWCEPLVC....................................................
E0W1V5_PEDHC/1-190                 ........................................................................................m-------------------------GLV.GLA......C..YRYCNFP...........---..--..---FQTWEMKP..ESKNqn.ggvGVL.LNIT........AA.VAIIEFLIK..................D-----G--KVSVNQLQN........GTTNAMQEH--.-...VG.I........FYRPKKLINILQNGGVDIFPPPDVFCYLEG--TV.-L.KHRAA.--ENHLYHCMSVMSTSHNFAWSRWNAPA--....GRRNMIL-----------.QMR................................EVTDKKRpP.NYNM......................LH.VT.PL.K...A.I.....LVDCTEVSASFND--------egiqgmkf............................................
G3H3D1_CRIGR/254-483               .......................................................................................gf--EIPRVLATSNVALRLLYTRYDHVTPL.RLTpateedY..EPMVVEP...........-VK..KE..EPIEKATTEEK..TVIEe....kASI.QEVE........PE.PKQEREFSL.................vQEEETNLEVLE--EIEVK........RTSDHEDENSE.T...NK.Y........ELEMRLLSEAVSAAQLHLVENIVD---------I.--.-PYAF.EKFQVDLCHFSTLGGVYHLDILELPPQYKP....VKGWVLV-----------.---................................EIRQEGL.Q.RFTYpp.................ettDE.PDpEN.A...F.P.....PIEVTLEVHKDVIFFEDPKV-i...................................................
B5DQT6_DROPS/773-989               .........................................................................................WTTKHIVSTTFDREANTITFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWSLQP..NEENp....dEII.LQLD........TY.HVRVFLYIT..................-----AKGVRGYATDLGS........AYTANPVKYLE.I...VE.P........ISDFRDFRKIFLEKNINIFAENDASFYIGKGYFS.-I.KHVAA.--ELHTYDVMALHCKLIKFYRSSWNRLA--....SRRDIIL-----------.GMK................................NAKDPSD.Y.SEVT......................MR.VT.PD.S...A.K.....FVKISELCSDDVNVIRLEYE-n...................................................
F7ET24_ORNAN/1-97                  .............................................................................leesesrsddfv----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.-----.GENVVDLHQFTPLGGIYHLDVLRLPPQRKQ....VKGWTLV-----------.EML................................S---GGL.Q.RFPYpp.................etlAR.AE.ME.V...IpP.....PITVTLKFNDNAMFFEEPTV-a...................................................
B2KFB9_MOUSE/228-456               .......................................................................................gf--EIPRILATSNVALRLLHTRYDHITPLfPIA......V..TEQNQNPvg.......aeQVN..VE..ESTEKAMTEEK..LFTE.....eKAA.NEDE........QP.KAEQERELN..................LVQEENKYEAIENTVLQR........TSDSE-GEDSQ.T...TQ.L........ELEMKLLSEAVLAAQQRLVENVVE---------L.-P.EASQA.--YKVDLCHFSTLGGVYHLDVLELPPQCKP....VKGWVLV-----------.---................................EILQEGL.Q.RFIYpp.................dttEE.PD.PDvT...F.P.....PIEVTLEIHKSVIFFERPRV-v...................................................
B0XK85_CULQU/188-390               ........................................................................................e-LAKPVSFDLRDALMRGLWTGYDHLSDL.EPT......F..RCGCLEP...........VPD..LL..ASQEIEWADRQ..NLRV......KRL.TEMR........EA.RAGFEAAQR.................qKELEEAEMA---------........----KS-----.-...--.-........-------SDETTVDIDGDFVQQEMQLYLQKMEQI.GP.DSLSLaGEEHVNLRRFRITGGTFSVSRFQKLPQPTEl.ssDFIYTTLPADLQLTEMQF.---................................-------.-.----......................--.VA.ET.S...E.D.....FIKITVKLPTFCFWWHEPVVC....................................................
B4E376_HUMAN/124-342               ......................................................................................gfe---TPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B3M6V2_DROAN/711-910               .........................................................................................WTTKHIIDLEINKVTHKLTFKTDRLGIF.GLA......F..KR----P...........---..--..-----------..---E......EVI.FSLD........TF.HVRILFYIS..................-----AKGVRGYVTDIIK........GYAAKPVKYLE.I...KE.P........IVDFKMLRKIFVAKNINIFAEHDASFYITNGYYS.-M.KHVAS.--EQHTYKMMALHCKSMKFYRSSWNRLA--....NRRDIIL-----------.GMK................................LAKDNTD.Y.SEVT......................VR.IQ.PE.S...T.T.....FVTVTENCSDQENVIVLSYK-n...................................................
B3S5Q5_TRIAD/360-559               ....................................................................................fndvk----------YDEATKMIAFKIDFFGPI.AIM......Q..DKYLNLP...........---..--..---FQFWEYTP..LDLNh....gKL-.-LFM........AA.ITEFEVEIK..................-----VINFD-DVCRIKL........T--AESPKEIElI...TD.K........WMSPQELMKCMEEIGIDVFPTIDSDKYVSI----.NP.KKKKL.--EFDVYRQIALTGSAYSYSWSKWNTEADS....GRDSIIL----RGVENLT.-AEea...........................ldyKIYMINR.Q.RASE......................LK.IT.EE.S...D.E.....---------------------yse.................................................
A7RZG1_NEMVE/358-564               ....................................................................................giddi---------QYNEEERTVSFKIADFGPI.ATV......Q..DLYLNMP...........---..--..---FQSWEIRP..CKQN......SCL.FTLI........AA.IIELEIEIK..................D-------ALCCVTQPED........LAQIDHFK---.-...-G.K........WMTPQELIKTLQRAGINVFPAVDAEKYVSI----.NK.KDSAL.--ETTIYKEMALLASSVGFSWSKWNADS--....GEDKIVL----QAAEQLEdDVI................................LEEDWSL.Y.LVTTrs.................sckLK.LK.EE.D...S.E.....F--------------------setnadntqlhsn.......................................
F1MDQ9_BOVIN/460-674               ........................................................wktdgisnvsykseerlitfnletfcpvtliqd----------------------------.---......-..-AHINMP...........---..--..---YQSWELRP..LDVN......KVL.LTIT........TV.FTELQIQIK..................ENLCMLASI-------KV........NNKNHS---SI.L...EE.K........WMTPVSFIIALKKAGLNIFPTGHS-----HLYVViNY.KHPSV.--EVKAYRQMALLSSAFAFCWSKWNTAC--....ESKKTVF-----------.QVK................................NQKYKTK.P.CKDPnwtlmf.........sgdraqsLK.IN.ES.S...D.A.....FSELKE---------------etefhstlyh..........................................
F1R213_DANRE/481-679               .......................................................................................wr--TDCISETSYDAESRTISFQMTAFYAF.TLL......Q..ETYANMP...........---..--..---FQSWELRP..LGQD......SAL.FTIT........GA.LIEVSITVK..................-------GKQCMLHTEET........KDLDHL-----.-...LG.K........WMSPSELQKAMRKAGINIFVNE----YSDKYVSI.NL.KDPLI.--EHAVYEQMALMSSAVAFSWSRWNAQC--....RQEHLVL-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------qaceqmevgpvaeeawslyllgaqrnqhlkmkeqedsfsp............
B4GUM2_DROPE/911-1127              .........................................................................................WTTNHILHSKFDVDKRTITIKTDCLGVF.GIA......F..NRYAHFP...........---..--..---FRHWCLEP..NEENp....dEVI.FTLD........TF.YVRIVMYIS..................-----KAGVRGYVIDLPK........EYQARPEKFMN.I...EE.P........ISDFIELRQRFQEMNINVFAEPDACFYIDKGYFT.-Q.KHLAT.--EVHVYNAMAVHCKLMRFTRSDWNRLA--....TRRDIVL-----------.GLR................................NPKDLVE.G.ADVT......................VR.VT.PD.S...A.T.....FVEVKELCSDDLDVIKLDYQ-p...................................................
B7Z092_DROME/253-515               ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSvip.....ncgLVD..IA..DSVMSEWMTQM..DIQE......DLV.VKME........TE.MRAYNEAIA.................fI-----------AQAEAK........EKRKSQKKKIA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNINL.LPSEVNLRRFIILGGIVSLVFVGKAKHASY....EKFNITLHEDGRVLRKSL.NILdesst......................eecsmQ------.-.---PskldigtdimrdtevgeaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPIVC....................................................
Q9VP91_DROME/64-326                ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSvip.....ncgLVD..IA..DSVMSEWMTQM..DIQE......DLV.VKME........TE.MRAYNEAIA.................fI-----------AQAEAK........EKRKSQKKKIA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNINL.LPSEVNLRRFIILGGIVSLVFVGKAKHASY....EKFNITLHEDGRVLRKSL.NILdesst......................eecsmQ------.-.---PskldigtdimrdtevgeaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPIVC....................................................
B4J1D2_DROGR/785-1001              .........................................................................................WTTKHIHNTKFDRQARTMTIETDRLGIF.GFA......Y..KRYDHFP...........---..--..---FRDWSMQP..NEENn....dEII.LTVD........TF.RARVVLYIT..................-----GQGIRGYVTDISN........VYVANPVKYLE.I...TT.P........ISDYRELRRRFYEKNVNIFAENDAGFYIENGYFS.-V.KHVAL.--ENHTYDAMSLHCKLMKFYRSSWNRLS--....SRRNILM-----------.CMK................................NAKDNTD.Y.TEAT......................LR.LT.PD.D...V.T.....FVEVSELCSDDLDVIKLDF--kl..................................................
B4IUJ4_DROYA/810-1026              .........................................................................................WTKKYIMESQIDLETNTLTFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWCLQP..SEDNp....dEII.LSLD........TF.HVRMIFYIT..................-----ARGVRGYVTDLVK........GYTAKPVKYLD.F...VE.P........ISDFRKLRKLLIEKNLNIFAENDASYYIKNGYFS.-I.KHIAS.--ELHTYNTMALQCKLMKFYRSSWNRLA--....QRRDIIM-----------.DMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVKISEMCSDDVNVVKLRYE-e...................................................
B5DQT5_DROPS/783-999               .........................................................................................WTTKHIVDTTFDRLNHTMTIKTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWSLQP..NEENp....dEII.LQLD........TY.HVRIYLYIT..................-----SKGVRGYATELSN........AYTAKPVKYLE.I...VE.P........VSDFRDLRKIFVEKNINIFAENDACFYIQRDYIS.-I.KHVAT.--EYHTYDVMALHCKLMKFYRSSWNRLA--....SRRDIIV-----------.GMK................................NAKDHSD.L.STVK......................LR.IT.PE.R...T.T.....FVEVQELCSDDINVIKLDF--qe..................................................
Q5RDT4_PONAB/93-275                ............................................................ekskvvlnlieklkfilletppcdlqdkn----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.IIQYQESIL..................-QLQELLHLKFSVATEIL........LRSSAE-EESE.A...IK.Y........EREMKVLSEIVSAAQLLLVENFSE-----KPDFF.--.-----.EDNVVDLCQFTALGGVYHLDILELPPQCKP....VMGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
H3BCR0_LATCH/372-478               .............................................................................aeleeeeeeeei----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.----L.ENDVVDLRQYITLGGVYYFDLVKLPPQPKQ....IKGWTIV----EL-----.--Ldsgle......................ffpypSETLKNN.S.SNVK......................IE.EK.EN.EtlaL.P.....PVGVTIKLPENVMFFETP---qi..................................................
B4IUJ3_DROYA/65-327                ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSmsp.....ncgLVD..IG..DSVMSEWMTQM..DIQE......ELV.TRME........SE.MRAYNEAIS..................----------FIADAEAK........EKKKPQQKRVR.I...PK.P........PKRPQELPTGMFPDPHKIFLEHEKRDCSDFFNRYfHP.DNINL.QPSEVNLRRFIIIGGIVSLVFVQKAKHTAF....EKCNITLHEDGRLLRKSLnILD................................GSKEEES.S.RRSTklgigadikr.ntvfeeasdvpLH.LE.PN.E...L.P.....YYFLTFKVPNHLCIWGEPMVC....................................................
F7AEU0_CIOIN/480-681               ......................................................................................wkt---SGITDTNFDEENRKLLFKTQEFGTF.CLM......Q..DSHLNMP...........---..--..---FQSWELKP..KGTN......STV.LTIT........AA.IAEVEIEVK..................DSKCRLNAP---AEDPPK........ELSGLYGKWMA.V...PK.-........------LIAAMRDAGVNVFPAEDSHKFVSI----.QS.KEVDL.---ERVYEQMAILSSTFAFSWSKWNNDA--....GSKQVI------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------iqiapclikenvprdavsdddwsifsvsddmsyklalseyde..........
G6CT66_DANPL/67-269                .........................................................................................WTSNYVNDYKFNEDKLTVQFRTGVLWPI.GIA......V..LRYGNLP...........---..--..---YQGWDIRP..DSNS.....kGVT.ISVT........GA.CVSVTFVCI..................GNSVRLKWIANATTPALK........EHF--------.-...-D.K........PYSVKKMVQIMREAACDFFPDFDGHNHVEG--SC.-P.KEWVS.--ERHNYHAMAFLSRAYNFQWSRWNAAA--....GSRNIII-----------.QFR................................EAVDRKR.EaKFHL......................LR.VT.PQ.R...A.V.....VLKCIELSPEF----------nmd.................................................
G3VSF6_SARHA/250-477               .......................................................................................gf--EIPKALATSDIAVRIFHTNYDHVSPL.PM-......I..PRLAKSE...........ITDviIE..DSAEKETAKDE..EVPQ......AGL.EEVA........EN.QELMTSSIFem.............dmtKTESSLV-------NSKK........SMISVK-DYAE.V...KK.D........EIELKSLRSDTYSLSLLA--PATKISVPDSIYEI.-V.N----.DEDIVDLKGFMPLGGIYHLNILKLPPQSKH....VKGWTIV-----------.---................................ELLSGGL.Q.PFVYppe...............iieeTT.ET.EN.P...Y.P.....PIEIFIEIKKNVVFFEKPMV-a...................................................
B3M6V4_DROAN/199-475               ........................................................................................t-VQLPLSVLHDNLTLRCIHFFFDPYSHL.AKS......Y..ELPGDQGntp.....icgIMN..IE..DSAASEWAAQV..DIQE......ELM.LKMS........NQ.MQVYQDAMEsvetiifrliiilyliifS---RVIEAEKTKIA---........ENKEMRLENKP.P...SK.L........PKKPQELPEGKVPDPYKIFIDREEQECKDFFMETfNP.RNINL.LPFEVNLRQYIMMGGIYSMVFLRKPKHTAF....QKFNITMHEEGRTLHVEQ.-LQadigle....................devgpsGTKRSHD.F.SLITe...................pdLH.LN.QD.D...L.P.....YFILTFKMPLHLCRWGEPMVC....................................................
E3WWE0_ANODA/335-485               ........................................................................kekktdsdddeqmpqdi----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------------DVDKIYTEHADELMKKERSKK.GA.KTLNL.AEYDVNMRSHRIVAGVYGIDYLEQPMQDIK....IAKKTLL----RTVPQPG.KLKrkkfyqpy................kppptpqpG------.-.---Vrrlpe............eieaeIK.QM.EE.N...LdK.....LALVSVQLPENVFWFEPPIVC....................................................
H9IEN6_ATTCE/324-578               ........................................................................................t-IKMPLDIDCYCMAIRALWVKYDHYSDS.SSS......Y..IMPKLTEeye.....slyTID..FL..TYCQNEYNSKL..KIRE......EQV.EGRR........LR.LEEKKAILE..................KMENLPVLVPT--KPERK........EKKLERMQGAK.R...SE.Q........EQESEQLPYLPTPDEIILQREEESRKEIRKLLFT.--.---RC.EKTEINLRKYKILGGVLHIDLVYQPPQPKD....MRRDIML----TTLQIPK.ELKsvpfykpy................kapppapdSERTPEI.I.EAEM......................KA.LE.AA.M...E.A.....LALITLKLPSSIIWFEPPLV-a...................................................
AXP83_CIOIN/481-683                ......................................................................................wkt---SGITDTNFDEENRKLLFKTQEFGTF.CLM......Q..DSHLNMP...........---..--..---FQSWELKP..KGTN......STV.LTIT........AA.IAEVEIEVK..................DSKCRLNAP---AEDPPK........ELSGLYGKWMA.V...PK.-........------LIAAMRDAGVNVFPAEDSHKFVSI----.QS.KEVDL.---ERVYEQMAILSSTFAFSWSKWNNDA--....GSKQVII-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------qiapclikenvprdavsdddwsifsvsddmsyklalseydee..........
Q29H75_DROPS/294-522               .....................................................................................qisl----PPTVRLQSSALRGLWLNYDHFSDY.CSS......Y..RLKHARS...........---..EN..ANILRQTKREW..RKRK......EIL.QAML........DE.CGRDIPLSE..................-----LEQ-------LTQ........EQHSASSQ---.-...--.-........------PPRERTYDVDKLYAEYEDELSRAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ....LNAHSFI----RTITCA-.---................................NSLVLKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.ES.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
E9IZ51_SOLIN/250-506               ........................................................................................t-VKMPIDIDCYCMAIRALWVKYDHYSDS.ATT......Y..IMPKLPEkye.....slyTID..FF..TYCQNEYNEKL..KIRE......EQV.EGRR........LR.LEEKKAILE..................KMENPPAPVPTKPERKGK........LQKKPGIQGAK.R...PE.P........EQEPEQLPYLPTPDEIILQRENETRKEIRKLLFT.--.---RC.EKTEINLRKYRILGGALHIDLVYQPPQPKD....MRREITL-TTLQIPKKLK.SVPffkpyk...................apppapdSERTPEV.I.EAEM......................KA.LE.AA.M...E.A.....LALVTLKLPSSIIWFEPPLV-a...................................................
Q179I2_AEDAE/817-1020              .........................................................................................WTTGSIHKQEYDPDCRTVTIWTEKLGTF.GFA......M..RRYYNLP...........---..--..---FRGWDMRR..IGKL.....sDLT.TCLT........LD.CVGLQFSIN..................------VTKSGY----TV........KFGAAPQD-IT.A...PT.K........ELSLEELAKYLTKVNLNIFPDVDAPFYVTEMTT-.-P.KHESM.--EIHTLKCMAAFCLTHNFTNCFWNKYA--....PFREALF-QSRQVIEGCP.---................................------E.Q.TFGT......................VM.VN.PL.K...A.A.....VVTVEELCS------------pldevi..............................................
F4WQP1_ACREC/242-497               ........................................................................................t-VKMPLDIDCYCMAIRALWVKYDHYSDS.SSS......Y..IMPKLTEeye.....siyTID..FL..TYFQNEYNTKL..KIRE......EQV.EGRR........LR.LEEKYTILE..................KIENLPDLIPTKPER-KR........NQQKKPEQMQE.V...KH.P........EQEPEQLPYLPTPDEIILQRADEFQKEIRKLLFT.--.-R--C.KKTEINLRKYKILGGVLHIDLVYQPPQPKD....MRRDIML----TTLQIPK.ELKsvpfykpy................kapppapdSERTPEV.I.EAEM......................KA.LE.TA.M...E.A.....LVLVTLKLPSSIIWFEPPLV-a...................................................
C3KGM0_DROME/250-510               .........................................................................................KVQVPLSVLCDCITIRCVHTDFDHHSPH.AKS......Y..EPLTVESifm....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NNMN........RR.REEYDELMQli..............aeRTEQAAKEAKFG----KG........GDGDKRPK-IV.I...PK.T........PKTVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYfHP.DNLSL.TPEEVNLRECIIVGGIYNISFVRRPDQTQF....EKFNIVLHEDGRVLKVIP.QVV................................AKQDNRK.S.RLTEytrmt............lgtsqMK.LS.EE.E...L.P.....FFVVTVQLPPHLCRWGKPEVC....................................................
B4N3V7_DROWI/913-1129              .........................................................................................WTTKYIQRTELDRDNLIVTVRTDRVGLF.GFA......F..KRYAHFP...........---..--..---FRHWCMEP..SEENa....nEIV.FTLD........TF.HVRVVLYIS..................-----NKGIRGYVTDLTK........EYTAKPVKYMT.I...EE.P........IFDFGDFRKRFQEKNVNIFAEHDAKFYIENGYYS.-L.KMLAL.--ELHVYDAMAIHCKMIKFFRSEWNRLA--....TRRNIVL-----------.CLR................................NPKDPNE.G.AEVT......................CR.VT.PD.N...S.T.....FVEVSELCSDDLDVFKLHYQ-p...................................................
B4R6W8_DROSI/870-1080              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................KSGYTVNNFQGGSTQ---........GITDMIGKTLS.L...AE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
F5H555_HUMAN/124-342               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
AXP83_CIOIN/356-472                ................................................................................eieddeeei----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.----L.DPDVVDLRQFSPLGGVYHVDLLKTPPQPNI....VRGWTLT----QIIDKPLsTVKypsdn.....................pntgrsS------.-.SRVAsanpeg.........rdegspsKT.PL.EQ.Q...Q.P.....PIGLTFALPSNVMFFEEPQV-a...................................................
H9JPC9_BOMMO/217-376               .............................................ilidllsestrsyglaaempnryedlfvfnvkehvetyklkkeq----------------------------.---......-..-------...........---..--..----------D..DIRN......KFY.KEIQ........QK.IREVENFLK..................--------------A--N........PYTKNEKE---.-...KE.E........LDNLNMAEPPFLPDPRTFMAEQNDLAFKKYLKTC.--.-SVKT.RSGEVNLRKYRICGGVLNLDLLTTPPQPKR....MRDSVTL-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------ttckc...............................................
B3NIU1_DROER/835-1048              .........................................................................................WTTEFILESSFNRQSKVVMVKTDRLGYF.GFA......Y..PRYAHFP...........---..--..---FRHWELEK..NEQNp....dEII.LTLD........TY.HVRVVFFVS..................-----SDGIRCHAIDVPK........EYIARPFKYID.I...DQ.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHVYDVIAVHIKLMKFSRSQWNRLA--....KDRDLVL-----------.CLR................................NTRDLHD.G.SEVT......................VR.VT.PE.V...A.S.....FVEVSELCSDDTKT-------ysdl................................................
B5DQT6_DROPS/219-498               ........................................................................................m-VQMPLSVLMDCLTLRCVHTSFDNYSQN.AKS......Y..EQAIPECdsy....pnagIAD..IQ..QSLMSEWHVQL..EMQE......MAL.AAMV........RR.REQYLELLQ..................LIEERTEQASKRGKE--Q........AQGKNKLPKIV.V...PK.T........PKMAPPVPEGMLPDIREAFYQREESDYKEYLNEIyHP.QKLNM.TADEINLRQHILLGGIYSIMFVRRPMQMQF....QKFNVVLHEDGRILHTMP.DVVadmgggyampe..........frrtqisqsrkQ------.-.---Tpvgsrirlt....talearqsnIR.LQ.DN.E...L.P.....YFIVTIQLPQGLCKWCEPLVC....................................................
CASC1_MACFA/242-460                .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SSATELVK..DDVEnv..ekAIS.KEVE........EE.SKQQEKQSH..................LIQEEKLKVEEEQDDIEV........KMGSAEEE-SE.A...IK.C........ELEMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.ENDMVDLFQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFENPMVV....................................................
B5DQI4_DROPS/911-1127              .........................................................................................WTTNHILHSKFDVDKRTITIKTDCLGVF.GIA......F..NRYAHFP...........---..--..---FRHWCLEP..NEENp....dEVI.FTLD........TF.YVRIVMYIS..................-----KAGVRGYVIDLPK........EYQARPEKFMN.I...EE.P........ISDFIELRQRFQEMNINVFAEPDACFYIDKGYFT.-Q.KHLAT.--EVHVYNAMAVHCKLMRFTRSDWNRLA--....TRRDIIL-----------.GLR................................NPKDLVE.G.ADVT......................VR.VT.PD.S...A.T.....FVEVKELCSDDLDVIKLDYQ-l...................................................
B5RID9_DROME/30-292                ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSvip.....ncgLVD..IA..DSVMSEWMTQM..DIQE......DLV.VKME........TE.MRAYNEAIA.................fI-----------AQAEAK........EKRKSQKKKIA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNINL.LPSEVNLRRFIILGGIVSLVFVGKAKHASY....EKFNITLHEDGRVLRKSL.NILdesst......................eecsmQ------.-.---PskldigtdimrdtevgeaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPIVC....................................................
B4QJL2_DROSI/800-1016              .........................................................................................WTKEYIMESQIDLETNTLTFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWCLQP..SDDNp....dEVI.LSLD........TY.HVRMFFFIS..................-----ARGVRGYVTDLVK........GYTAKPVKYLD.I...VE.P........ISDFRELRKLLIEKNLNIFAENDANYYITNGYFS.-I.KHIAL.--ELHTYNTMALQCKLMKFYRSSWNRLA--....QRRDIIV-----------.EMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVKISEMCSDDVNVVKLRYE-e...................................................
B3MXV6_DROAN/917-1127              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................EFGYTVNNFQGGSTQ---........GITDMIGKTLS.L...GE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
B4IAI2_DROSE/253-515               ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSvip.....ncgLVD..IA..DSVMSEWMAQM..DIQE......DLM.VKME........SE.MRAYNEAIS.................fI-----------AEAEAK........EKRKPQKKKVA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNMNL.LPSEVNLRRFIIIGGIISLVFVRKAKHSSY....EKFNITLHKDGRVLSKSL.NIL................................DESSTEE.S.SMQPtkldigtdimrdtevgeaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPVVC....................................................
Q1PQG8_DROMI/3-53                  ..........................................................................asalsaarssqfrlt----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.-----.------------------------------....------------------.---................................-------.-.---Led.................ignMR.LD.PD.E...L.P.....YFIVVLDLAPELCLWGEPKVC....................................................
F1P406_CHICK/239-456               .......................................................................................fd---LPKSLAVSSIAVRILHTHYDHVSPL.WLQ......C..QRVPRLE...........---..VL..DSQELTQRSQD..NAGEp....eEEE.KEAK........EEpNVTAEEETL.................pDERNSAISFRGNTNSIAD........TNEVTE---EE.T...EK.K........PENLDVTPEGI----VLALLCMEEK-------TS.EE.EEMIT.DESTVDLQQFVPVGGVYRIDGLQLPPQVQQ....INSWCVV-----------.---................................ELLDGGL.E.AYPYp....................pQE.SE.DT.T...H.P.....PIQITLGLPDSVIYWKEPM--ia..................................................
Q9VP91_DROME/650-866               .........................................................................................WTTEFILESSFNKESKVVIVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNh....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYVHRPFKYID.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHIYDAIAVHGKLMKFSRSQWNRLA--....KDRDLVL-----------.CLQ................................NTRDIHD.G.SEVT......................VR.VT.PE.V...S.T.....FVDVSELCSDDTKVIKLNYK-s...................................................
B4PE86_DROYA/198-453               .............................................................................yrvlrlqdaymd-----------------LHTDFDNISQN.AKS......F..DTPVAASvny....psagLVD..IE..ESVVNEWHMQH..DIQE......ETL.SLML........AR.RREYEDMMQii..............aeKTEQAAKAA-------KQ........TDPDKAVK-IL.I...PK.A........PKEPPEVPTGMFPDIYEDFLRMEDSQYLGYLDEVyHP.RHLDM.QPFEINLREHIILGGIYSIMFIRRPDQTQF....EKFNIVLHEDGRVVHILT.EMKadikee...................tlrsskiARKTRET.-.---Yrg..................tkIK.LE.DD.E...L.P.....YFIVTLQVAADLCKWSEPVVC....................................................
Q7KTX4_DROME/257-517               .........................................................................................EVQIPKSVLKDCVTIRSLHMDFDNISQN.AKS......F..EIAVKASlny....pnagIVD..IE..NSVVNEWHMQL..EIQE......ETL.NLML........TR.RREYEDMMEli..............aeKTEQAAKAA-------KQ........TDPDKMVK-IT.I...PK.A........PKEPPYVPTGMFPDIYEDFLRIEESQYSGYLDEVcHP.RHLDM.QPFEINLRDYIMLGGIYSIMFIRRPDQTQF....EQFNIVLHEDGRVVHILT.EMKadipve...................avrksniGRKTRET.Y.RGTK......................IK.LE.DD.E...L.P.....YFIVTLQVAADLCKWSEPVVC....................................................
G1LM06_AILME/242-459               .......................................................................................gf--EIPRILATSDIALRLLHTHYDHVTPL.RPV......P..ASLQERTa.........tVTD..F-..--VK---EEVK..NEEA......AIS.KELQ........EE.GKQRENESN..................SVHEEETKFEE-QGDSEV........QMGVGQE-ESE.A...TK.G........ELEMKLLSETVLSAQLLLIENANE----------.--.KPCFF.EDNEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMIV----------E.ILK...............................eGLRKYIY.P.PETT.....................eDV.ET.EN.A...F.P.....PIEVTLEVQENVIFFEDPVV-a...................................................
F5HMV4_ANOGA/265-504               .......................................................................................lh---RPPALDLKDCLIRGMWLEFDHHSNM.DPT......H..TIPALEP...........TVE..LI..PAQEAEWNERQ..EVKR......KQL.TALR........KL.REDYDAEQCr................kQAEAEALEAQKGGKDTKKpaaavaapKAGGKKGKSPK.Q...PPvP........EPEPAVITDETEVDIDAEFERQEADRFWDTLASV.SP.KARPL.RPGYINLREYAIVGGVFKLARFDRLPQPMEp.rpDFIYTNVPDGLQLTE---.---................................-------.-.-KGY......................RA.LE.PE.E...L.-.....-IKIELQLPAHCHWWEEPTVC....................................................
E1ZWH8_CAMFO/214-470               ........................................................................................t-VKMPLDIDCYCMAIRALWLNHDYNSDC.AIS......YvvPRLPDEYe.........sMYD..IDflSFCQNEYDTKL..KIRE......DQV.EGRY........LR.LEEKKAILE..................RIENPPVQVPTKPERKGK........QPKKAGAPGAK.R...PE.P........EQETEQLPYLPTPDEIILQREDESRKEIRKLLFT.--.---RC.EKTEINLRKYRILGGILHIDLVYQPPQPKD....MIKDIML----TTLQIPK.KLKfvpfckpy................kapppapdSERTPEV.I.EAEM......................KA.LE.TA.M...E.E.....LVLVTLKLPSSIIWFEPPLV-a...................................................
B4J1D2_DROGR/244-506               .........................................................................................EVQMPLSVLHDCLTLRCIHTKFDNHSQY.AKS......F..DPIIPDSpvq....anggIVD..IE..DCLINEWLMQL..DIQQ......ELL.ASMM........AK.RENYEDIMR..................TIAEKTEKM----NKEKK........ANEGKSTK-TV.I...PK.A........PKEPPLVPPGMFPDAYATFLEREQQQYLDTLDEIyNP.RHLKL.TSDEVNMRQHIMLGGLYSIMFVRQTPGTHY....EKFNIMLHEDGRILHIMD.DIVadlraptw................addvsarrSRLQMDE.Q.KRKT......................LN.ID.ET.E...L.P.....YFFVTIHMPRELCMWGDPIAC....................................................
B7Z095_DROME/836-1052              .........................................................................................WTKEYIMESQINLETNTLTFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWCLQP..SEDNp....dEVI.LSLD........TF.HVRMFFYIS..................-----ARGVRGYVTDLVK........GYTAKPVKYLE.I...VE.P........ISDFRELRKLLIERNLNIFAENDASYYITNGYFS.-I.KHIAL.--ELHTYNTMALQCKLMKFCRSSWNRLA--....QRRDIIV-----------.EMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVKISEMCSDDVNVVKLRYE-d...................................................
E1ZWH8_CAMFO/479-687               .........................................................................................WSTQDVHDIKYNEEKQTITFRTGRLGIH.GLA......A..LKFVNIP...........---..--..---FQSWELKP..EMGRna..rgGVV.LNIS........GA.IIQAEFIVR..................EDLICLNSLAGGMSTALK........EMIGEY-----.-...--.-........-MKLYLLIEKMRNAGCDLFPERDAFSYVKALS--.-V.KHPAT.--EKHLRECIAMLCTTYTFSWSRWNASR--....NSREIVI----QFKEHHG.CVA................................K-----E.R.TNLT......................LL.IT.PS.Q...T.M.....TVSCTEVSSEFSD--------vpl.................................................
Q17M71_AEDAE/726-911               .........................................................................................WSTRDIHDVKFNEDKLTIQFRIGRLGAI.GFA......A..NRYSNLP...........---..--..---YQSWELKP..DLKNp....gSVT.FSLT........AA.VVSTEISIS..................-----EHGFRVN--SLQG........G---PTQALQE.I...LG.Q........VLPMRKMMKQLRLAAVDLFPEDDAFNYSEG--SC.-E.KNPIM.--ESHLYDCIGLLALTHNFSWSRWNLLS--....------------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------gcrmcvllmreiiehrripihstllvtp........................
E3WWE0_ANODA/829-946               .............................................................................tqalqeilgvtm----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........--SLRKLVKTLRLAAVDLFPEDDAFNYTEG--TC.-E.KNPIM.--ESHLYDCMGLLALTHNFSWSRWNLLS--....GCRMCVL-----------.LMR...............................eIVEHRRL.P.NHST......................LL.VT.PL.K...A.S.....VIDT-----------------vevspvfn............................................
G1TAN0_RABIT/241-463               .......................................................................................gf--EIPRILAASDIALRLFHTHYDHITPL.RPM......P..PPPPLPE...........---..--..---EENTPTVP..EIVK......EEV.KVVEeavnqedqEE.SRQQESESNl................iNEEEKDEPIKNL---STV........RTSKSCGEESE.P...PK.C........EPKIALLSKKISAAQLLLIKNA------------.-P.EKPGIfEENEVDLFQFTTLGGVYNLEILELPPQCKP....VKGWMIV-----------.---................................ELLKEGL.Q.KYTYppe................tveDN.ET.EN.A...F.P.....PIEVTVEIHENVVFFEDPEV-v...................................................
B4R6W8_DROSI/249-477               qislpptvylqssalrglwlnydhfsdycssyclkharsananilrqtkrewrkrkeilqamlddcgreiplseleqltqdqhsassqp----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------PRERTYDVDKLYAEYEDELSKAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ...lN-ARSFI----RTITSA-.---................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
B4IAI3_DROSE/215-475               .........................................................................................KVQVPLSVLCDCITIRCVHTNFDHHSSH.AKS......Y..EPLTVESiym....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NNMN........RR.REEYEELMQli..............aeRTEQAAKEAKFG----KG........GDGDKRPK-IV.I...PK.T........PKLVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYfHP.DNLSL.TPEEVNLRECIIVGGIYNISFVRRPDQTQF....EKFNIVLHEDGRVLRVTP.QVVa.............................kpDNRKSRI.T.EYTRmtl...............gtsqMK.LS.EE.E...L.P.....FFVVTVQLPPHLCRWGKPEVC....................................................
F1ME26_BOVIN/242-458               .......................................................................................gf--EIPRILATSDIALRLLHTHYDHVTPL.SPV......L..TPSQEHI...........---..--..---SIVTDFVK..EEVKs...vqTAV.SKDL........QE.ENKQENESNs................vH--EEETKAEG-QGDVEE........QMCPVQ-EEPE.A...TK.Y........EMEMKLLSETVSAAQELLLENASE----------.--.KPYFL.EENEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDL.EA.EN.V...F.P.....PIEVTLEVHENVIFFENPMV-a...................................................
B4L2A1_DROMO/288-516               .....................................................................................nlsl----PPTVQLQSSALRGLWLNYDHFSDY.CSS......F..QLKHARS...........---..--..---ENATILRQ..TKREwr.krkEIL.QSML........DE.CARDIPLSE..................-----LEQ-------LTQ........EQHSSSSQ---.-...-P.-........-------PRERSYDVDKLYAQYEDELNKARRRAV.GP.EAYGL.LETDVNLRKYRIISGVYCIDFLETPQQDKQlnarSFIRTIF-------AT--.---................................NNLMHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPIAC....................................................
B4IAI2_DROSE/839-1055              .........................................................................................WTTEFILESSFNRESKVVMVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNp....dEII.LTLD........TY.HVRVVFFIT..................-----KDGIRCHAIDIPK........EYVPRPFKYID.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHIYDAIAVHGKLMKFSRSQWNRLA--....KDRDLVL-----------.CLR................................NTRDIHD.G.SEVT......................VR.VT.PE.V...S.T.....FVDVSELCSDDTKVIKLNYK-n...................................................
B4IAI4_DROSE/721-920               .........................................................................................WTTKYVKDTVIDRETNRITFKTDRLGLL.GLA......F..KR----P...........---..--..-----------..---D......EII.LSVD........TF.HVRIFFYIT..................-----CKGVRGYVTDLSK........GYTAKPIKYLE.I...VE.P........ISDFRQMRQIFINKNINIFAENDASFYIENGYFS.-M.KHVAL.--EMHTYNIMALHCKLMKFYRSSWNRLA--....DRRDIIL-----------.GMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVQISENCSDKVNVIVLSY--ts..................................................
B5DQI4_DROPS/263-545               ........................................................................................h-IQLPFSVLCDNMTVRCVHTFFDPYSER.SKS......F..EMVIDSTslp.....hagLLD..IE..DSVIDEWLTQV..DIQD......EII.TKME........SA.MQQYEDIRA..................N-IEAIQPTRKS----KK........DVKTKGQQQGK.P...MK.A........PKEPQALPEGMFPDPYKIFIDREQQEYLNFMDQSyNPaKNPSI.-PGEINLRRFILIGGIFAVDFVRKPKHTAF....EKLNITLHEDGRILYVDRnRMVdeadevglfssrshhgtireapsrltaapsrhE------.-.---Vksaplee........ttedgtiLY.LG.KN.E...L.P.....FFFLTFDLPRHLCRWGSPTVC....................................................
B4NPH6_DROWI/294-522               ......................................................................................qis---LPPTVRLQSSALRGLWLNYDHFSDY.CSS......F..QLKHSRS...........---..--..---ENATVLRQ..TKREwr.krkEIL.QAML........DE.CARDIPLSE..................-----LEQL-------TQ........DQHSTSSQ---.-...--.P........-------PKERTYDVDKLYAEYEDELNKARRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQlnarSFIRTIM-----------.-VA................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPIAC....................................................
B3KS92_HUMAN/242-460               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B4J1D1_DROGR/257-524               ........................................................................................r-VQIPLSVLCDNLTLRCVHSFFDHVSES.AKS......F..GQQMDMCpna....lnggMMD..IE..DCLINEWLMQV..DIMD......KMI.NKLE........LK.IMEYKKFMS..................-QMSVKVAPPKWGEIDQK........KRKSDKSSKSK.N...VK.K........PKEPQNLPDGMFPDPYDAFLEQEQQEFDEFLDKFmNP.LNLKL.GPHEVNLRYFNMIGGLYSLFFVPKPKHTHF....QKFNITLHKDGRILHRSE.EVLadm..........................gdvGEKTDHR.S.PLTRrsaye...........daknlnLK.LQ.DD.E...L.P.....FFWITFQLPEYLCRFGEPLAC....................................................
B4Q2N1_DROYA/905-1115              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................KSGYTVNNFQGGSTQ---........GITDMIGKTLS.L...AE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
F4WQP1_ACREC/506-713               .........................................................................................WSTQDVHDIKYNEEKQTITFRTGRLGIH.GLA......T..FKFINIP...........---..--..---FQSWELKP..EISRdv..hgGIV.LNVS........AA.IVQAEFIVR..................EDLVCLNSLAGGISTAL-........-------K--E.I...IG.K........YMKLHILIEKMRDIGCDLFPERDAFSYVKALP--.-V.KHPVT.--EKHLRKCMALLCTAYTFSWSRWNASR--....HSREIVI---------QFkELH................................GC-VAKE.R.TNLT......................LL.VT.PL.K...T.V.....IISCTEVSSEF----------ssvp................................................
B0XK85_CULQU/769-971               .........................................................................................WSTRLVHRQEYDPDGKVVTFWVSKLGSF.GFA......M..QKSFNFP...........---..--..---FKEWDMRR..TGKV.....aDLT.TTIT........LN.CPGITVSIS..................---ITLAGYRLAFE----........---NAP-QNIT.P...PA.D........FLSLDQLEKYLTRINLNLFPEPDAPFYVSGMAT-.-P.KHESL.--ELHTLKCLAGFCLTHNFSRSFWNNFA--....PHREVVF-------RARQ.---................................LIEGRQE.P.DFVT......................VM.AN.PL.K...A.A.....TVTVEESCS------------pldqv...............................................
B7Z092_DROME/839-1055              .........................................................................................WTTEFILESSFNKESKVVIVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNh....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYVHRPFKYID.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHIYDAIAVHGKLMKFSRSQWNRLA--....KDRDLVL-----------.CLQ................................NTRDIHD.G.SEVT......................VR.VT.PE.V...S.T.....FVDVSELCSDDTKVIKLNYK-s...................................................
B4NPH6_DROWI/913-1123              .........................................................................................WSTRDVHDTKFNEDKLCIQFRTGRMGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTIL.FSFT........AS.LISLDMTIT..................AEGYTVNNFQGGSTQ---........GITEMIGKTLS.L...SE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLALSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
B4N3V7_DROWI/251-528               ........................................................................................s-LQMPFSILGDNLTLQCVHTFFDPYSEK.AKS......H..DVEIETDtsn....issgMVD..IE..DCLIAEWLKQV..EIQE......EVI.AKME........SK.MQQYEDAMS..................-ILQAKESATG-----KN........KEDANK---AK.A...LR.A........PKQPQGLPEGMIPDPHHIFLDHEEQQFIDFLNDSfHP.SKLDL.RPDEINLREFLILGGIFSLAFVRKPKHTDY....EKFNITLHEDGRVVYIRQ.EVRigneseddeeehf.....gpllasmsqqltrrE------.-.--TTrstrsrlq.....laemeadakIR.LN.DD.E...L.P.....FFFVTFKLPRELFLWGEPVAC....................................................
B4L2A1_DROMO/888-1098              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTIF.FSLT........AS.LISLEMTIT..................EAGYTVHNFQGGSTQ---........GLTDMLGKTLS.L...SE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNFVM.--EMHTYACISTLALSHNFSWSRWNLLA--....GSRTAVL-----LIRELL.---................................--EGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIAGM--ey..................................................
F7A7N4_MACMU/196-414               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SSVTELVK..DDVEn...veKAIsKEVE........EE.SKQQEKQSH..................LIQEEKLKVEEEQDDIEV........KMSSAEEE-SE.A...IK.C........ELEMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.ENDMVDLFQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFENPMVV....................................................
B0WSR7_CULQU/751-951               .........................................................................................WSTRDIHDVKFNEDKLTIQFRIGRLGAI.GFA......A..NRYSNLP...........---..--..---YQSWEMKP..DIKNp....gCIT.FSLT........AA.VISTEITIS..................-----EAGFRVN--SLQG........GPTQAM---QE.L...IG.Q........VLPLRKMIKTLRQAAVDLFPEDDAFNYSEG--SC.-E.KNWIM.--ESHLYDCMGLLAVTHNFSWSRWNLLS--....GCRMCVL-----------.LMR...............................eIVEHRRL.P.THST......................LL.VT.PL.K...-.-.....---------------------avivdsvevspvf.......................................
B3NIU2_DROER/808-1024              .........................................................................................WTKEYIMDSQIDLEKNTLTFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWCLQP..SEDNp....dEIM.LSLD........TF.HVRMFFYIT..................-----ARGVRGYVTDLVK........GYTAKPVKYLD.F...VE.P........ISDFRELRKLLIEKNLNIFAENDASYYIKNGYFS.-I.KHIAT.--ELHTYNTMALQCKLMKFYRSSWNRLA--....QRRDIIM-----------.DMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVKISEMCSDDVNVVKLRYE-d...................................................
H9K7G0_APIME/642-854               .........................................................................................WSTKDIHDIKYNEEKQTIAFRTGRLGIH.GLA......G..YKYANLP...........---..--..---FQSWELKP..EKKKsgcvhiGVI.LTIT........AA.MVQAEFLIR..................EDQVCLKSF--------T........GITSTPLEKIL.G...E-.-........YFELEYLIERLQQVGCDLFPERDAASYLKGLP--.-I.KHPIA.--EKHLRECMALLSTSYIFSWSRWNATR--....DFREIVL----QFKEAHG.CIA................................-----KE.R.TNVM......................LL.VT.PS.R...T.M.....RIRCTEVSSEFS---------dlpled..............................................
B4QJL1_DROSI/839-1055              .........................................................................................WTTEFILESSFNRESKVVMVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNp....dEII.LTLD........TY.HVRVVFFIT..................-----NDGIRCHAIDIPK........EYVPRPFKYID.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHIYDAIAVHGKLMKFSRSQWNRLA--....KDRDLVL-----------.CLR................................NTRDIHD.G.SEVT......................VR.VT.PE.V...S.T.....FVDISELCSDDTKVIKLNYK-n...................................................
B4LB73_DROVI/906-1122              .........................................................................................WTTKYINRTVFEPETLTIKIQTDRLGIF.GFA......Y..KRYEQFP...........---..--..---FRNWTLQY..NEEDi....nEIV.FKLD........TF.HVSIYLFIT..................-----NAGIRGYVTKMTT........EYTARPVKYLE.I...KE.P........ISDYRELRRRFCEKNINIFAEHDACYYIENGYFS.-E.KHLAT.--ELHVYDAFAIHCKLMKFYRCDWNRLA--....TRRNIVL-----------.CLR................................NPKDLND.G.ADVT......................VR.VT.PD.N...S.T.....FVEISEACSDNLDVIKLDYQ-p...................................................
C3Z1T6_BRAFL/34-226                .....................................................................................ftdi---------KFDEENKTLSFKTNTFGLL.TVI......Q..DSHLNMP...........---..--..---FQSWEIRP..RGNN......AAL.FTII........AA.IVELEIEIK..................D-----DKC--C---LSQ........PEDTPELD--H.L...RK.K........WLAPKDLVKALKAAGVNIFPEPDSSKFVSM---T.-K.KDEEA.--EMLTYRCMAMTLPAFAFSWSKWNAEAGE....DRI---------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------vmqaaehledepvneddwccyvqsvrrakklkinefseef............
Q29H75_DROPS/911-1121              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTIL.FSFT........AS.LISLDMTIT..................EAGYTVNNFQGGSTQ---........GLTEMIGKTMS.L...SE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNSVGIAG---mey.................................................
G1NLQ6_MELGA/239-451               .......................................................................................fd---LPKSLAVSSIAVRILHTHYDHISPL.WLQ......C..QRVPRLE...........---..--..-VLDSEELTQH..SQDN.....aGKP.EEEK........EA.REEPKVTTE..................---EEMLP---------V........ERNVAQVR--R.N...TN.S........ITDINEVTEEESEKKLESFDIPPEVQILQMQEKTsEK.EEMIT.DENTVDLQQFVPVGGVYHIDGLQLPPQVHQ....INSWSVV-----------.ELL................................D-SGLEV.Y.PYPP......................EE.SE.DT.T...H.P.....PIQITLGLPDSVIYWKEPV--ia..................................................
B3NIU3_DROER/223-483               .........................................................................................EVQIPKSVLTDCVTIRSLHTDFDNISQN.AKS......F..DTAVKASlny....ptagIVD..IE..ESVINEWHMQH..EIQE......ETL.SLML........TR.RREYEEMMLii..............aeKTEQAAKAA-------KQ........TDPDKAVK-II.I...PK.A........PKEPPEVPTGMFPDIYEDFLRMEDSQYLGYLDEVyHP.RHLDM.QPFEINLREHIMLGGIYSIMFIRRPDQTQF....EKFNIILHEDGRVVHILT.EMKadiktd...................tvrslsiARKTRET.Y.RGTR......................IK.LE.VD.Q...L.P.....YFIVTLQVPADLCKWSEPVVC....................................................
F6SGF8_MACMU/196-414               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SSVTELVK..DDVEn...veKAIsKEVE........EE.SKQQEKQSH..................LIQEEKLKVEEEQDDIEV........KMSSAEEE-SE.A...IK.C........ELEMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.ENDMVDLFQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFENPMVV....................................................
H2ZH41_CIOSA/225-439               ......................................................................................tfe---LPKVLAMADIAVRILRTKFDHYSHQ.CSS......F..QPKIKKP...........---..-K..EEVITPFSIPE..PELPv...etSVE.DKVEt......gSH.KEEDEDTTS..................VTDEGRKSVE--NDPAKE........EEKTDETK---.-...--.-........-NAENEGNESTNPSEIKVTVDEDE------LDDI.--.----L.DPDVVDLRQFSPLGGVFHVDLVKTPPQPNV....VRGWTLT----------Q.ILD................................KPLTAVK.Y.PSDNp....................nVG.KS.AS.R...Q.P.....PIGLTFTLPQDVMFFEEPQV-a...................................................
B4IUJ3_DROYA/788-1004              .........................................................................................WTTEFILESSFDRESKVLLVKTDRLGHF.GFA......Y..RRYSHFP...........---..--..---FSHWELER..NEQNp....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYIARPFKYIN.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHVYDAIAVHIKLMKFSRSQWNRLA--....RDRDILL-----------.CLR................................NTRDVHD.G.SEVT......................VR.VT.PE.V...S.T.....FVEVSELCSDDSKVIKLHF--ks..................................................
B3M6V3_DROAN/215-476               .........................................................................................EVQVPISVLDDCLTIRCVHTSFDHYSQN.AHS......A..PDYVVDNdym....psagIKD..ME..ESLISEWLLQQ..DIQS......EVL.DAMN........QR.YQDYQDTLN..................LIAERTEQA---AKADKS........DADGRKSK-II.I...PK.I........PKLVNPVPPGMLPDIYQEFIHREEKQYKSFLDVAyDP.KHISL.MPKDLNMRAHIIAGGIYSLMVVRRPEQTAY....QNLSVLLHEDQRKIKNLA.DVVcrtdfkg..................qsmslrvSEFV---.-.---Radq...............rnslFK.LN.ES.D...L.P.....YFHVTMKLPPDLCRWGTPKVC....................................................
E1NZC6_DROME/1-193                 .........................................................................................----------------------------.---......-..-------...........---..--..-----------..----......---.--ME........TE.MRAYNEAIA..................----------FIAQAEAK........EKRKSQKKKIA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNINL.LPSEVNLRRFIILGGIVSLVFVGKAKHASY....EKFNITLHEDGRVLRKSL.NILdesst......................eecsmQ------.-.---PskldigtdimrdtevgeaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPIVC....................................................
H2ZH40_CIOSA/239-481               ......................................................................................tfe---LPKVLAMADIAVRILRTKFDHYSHQ.CSS......F..QPKIKKP...........---..-K..EEVITPFSIPE..PELPv...etSVE.DKVEt......gSH.KEEDEDTTS..................VTDEGRKSKQS-----VE........NDPAKEEEKTD.E...TK.N........AENEGEKEESTNPSEIKVTVDEDE------LDDI.--.----L.DPDVVDLRQFSPLGGVFHVDLVKTPPQPNV....VRGWTLT----QILDKPLtAVKypsdnpn..................vgksasrV------.-.---Asanpegr........eeqgspsKT.PL.EQ.Q...Q.P.....PIGLTFTLPQDVMFFEEPQV-a...................................................
H2NJA5_PONAB/1-126                 ......................................................................................ssa----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........------EEESE.A...IK.Y........EREMKVLSEIVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VMGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
F6W570_HORSE/13-230                .......................................................................................gf--EIPRILATSDIALRLLHTHYDQVTPL.RPV......P..TSLQEHT...........---..--..---STITNLVR..DEEKnl..eaAIS.KEMQ........EE.CKQEENESNs................vHEEEIKVEDQG---ETEV........KMSSVQ-EEPE.V...TK.C........ELEMKLISETVLAAQLLLLENAHE----------.KP.SDLDD.--NEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMVV----------E.ILK...............................eGLQKYIY.P.PETT.....................eDF.ET.EY.S...F.P.....PIEVTLEVHENVIFFEDPMV-a...................................................
H9FI63_MACMU/1-86                  ........................................................................................f----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........----------------------------------.--.-----.ENDMVDLFQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFENPMVV....................................................
B4L9E9_DROMO/665-881               .........................................................................................WTTRYIKHTEFLPESCTLKIQTDRLGVF.GFA......F..KSYEHFP...........---..--..---FKGWSLQY..NKDNi....nEII.FTLD........TY.HVRVVLFIT..................-----NAGIRGYATKIIE........EYVANPIKYLE.I...KE.P........TSDFTELRRRFCENNINIFAAHDACYYIEKGYFS.-Q.KHLAT.--ELHVYDAFAIHCKLIKFYRCDWNRLA--....PRRNILL-----------.CLR................................NPKDVND.G.ADVT......................IR.VT.PD.N...S.T.....FVEVSEACTDDVDVIKLSYH-l...................................................
B4DY27_HUMAN/236-454               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B4PE87_DROYA/442-704               ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSmsp.....ncgLVD..IG..DSVMSEWMTQM..DIQE......ELM.TRME........SE.MRAYNEAIS..................----------FIADAEAK........EKKKPQQKRVR.I...PK.P........PKRPQELPTGMFPDPHKIFLEHEKRDCSDFFNRYfHP.DNINL.QPSEVNLRRFIIIGGIVSLVFVQKAKHTAF....EKCNITLHEDGRLLRKSLnILD................................GSKEEES.S.RRSTksgigadikr.ntvfeeasdvpLH.LE.PN.E...L.P.....YYFLTFKVPDHLCIWGEPMVC....................................................
E2R895_CANFA/250-456               ......................................................................tnfiththhrhkkafypvq----------------------------.---......-..-------...........ISD..QT..GSIIITCLLKK..DTKNv....lRYL.FKLL........NR.ISHRILLYKni..............lmEFEFTVLELKS---EIEI........SLSSFVQEESD.A...TK.C........ELEMKLLSETVLSAQLLLIENATE----------.--.-KPTFfEDNEVDLCQFTTLGGVYHLDILELPPQYKP....MKSWMIV----------E.ILK...............................eGLQKYIY.P.PETT.....................eDV.ET.EN.A...F.P.....PIEVTLEVQENVIFFEDPMV-a...................................................
G3T9E2_LOXAF/241-463               .......................................................................................gf--EIPRILATCDIALRLLHTRYDHVTPL.CPV......P..RPLKVVQ...........---..-D..PSTIIEPVKNQdtDIVK......EAI.SKED........QE.QSKQPGSESv................mVHEEIKVNIVEP-IIYNF........FSDGQGEEESE.A...MK.F........EVEMKLLSETVSAAQLLLLENSCE-----KPEFF.--.---EA.--NEVDLFQFTTLGGVYHVDILELPPQCKP....VNGWMIV----------E.---................................-ILKEGL.Q.KYKYppe................tteDF.ET.EN.A...F.P.....PVEVMLQVQENVIFFEDPMV-a...................................................
Q9VWZ4_DROME/233-461               qislpptvhlqssalrglwlnydhfsdycssyclkharsananilrqtkrewrkrkeilqamlddcgreiplseleqltqdqhsassqp----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------PRERTYDVDKLYAEYEDELSKAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ...lN-ARSFI----RTITSA-.---................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
F6W570_HORSE/239-452               ...............................................................................wktdgisnvs----------YKSEERLITFNLETFGPV.TLI......Q..DSHINMP...........---..--..---YQSWELRP..LDVN......KVL.LSVT........TI.FAEIQIQIK..................ENLCMLASI-------KV........NNKKHS---SI.L...EG.R........WMTPVSFITALKEAGLNIFPTRHSHFYVII----.--.-NYKVpLTEMKAYRQMALLSSAFAFGWSRWNMLC--....DSKKVVF-----------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------kvrehlrkeepiedpnwallmfsgdraqrlkideysdtfsealkeetefhst
B3NT98_DROER/902-1112              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................KSGYTVNNFQGGSTQ---........GITDMIGKTLS.L...AE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
H2NJA6_PONAB/1-126                 ......................................................................................ssa----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........------EEESE.A...IK.Y........EREMKVLSEIVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VMGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B4M6R7_DROVI/889-1099              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTIL.FSFT........AS.LISLEMTIT..................EAGYTVHNFQGGSTQ---........GITEMLGKTLS.L...AE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHTYACISTLALSHNFSWSRWNLLA--....GSRTAVL-----LIRELL.---................................--EGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIAGM--ey..................................................
D2H1A8_AILME/145-362               .......................................................................................gf--EIPRILATSDIALRLLHTHYDHVTPL.RPV......P..ASLQERTa.........tVTD..F-..--VK---EEVK..NEEA......AIS.KELQ........EE.GKQRENESN..................SVHEEETKFEE-QGDSEV........QMGVGQE-ESE.A...TK.G........ELEMKLLSETVLSAQLLLIENANE----------.--.KPCFF.EDNEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMIV----------E.ILK...............................eGLRKYIY.P.PETT.....................eDV.ET.EN.A...F.P.....PIEVTLEVQENVIFFEDPVV-a...................................................
B4H069_DROPE/910-1120              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTIL.FSFT........AS.LISLDMTIT..................EAGYTVNNFQGGSTQ---........GLTEMIGKTMS.L...SE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNSVGIAG---mey.................................................
B4DX11_HUMAN/72-264                ..................................................................emntfislwkeytsavtelvkdd----------------------------.---......-..-------...........---..--..---------VK..NVEK......AIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
F1MDQ9_BOVIN/235-451               .......................................................................................gf--EIPRILATSDIALRLLHTHYDHVTPL.SPV......L..TPSQEHI...........---..--..---SIVTDFVK..EEVKs...vqTAV.SKDL........QE.ENKQENESNs................vH--EEETKAEG-QGDVEE........QMCPVQ-EEPE.A...TK.Y........EMEMKLLSETVSAAQELLLENASE----------.--.KPYFL.EENEVDLCQFTTLGGVYHLDILELPPQCKP....MKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDL.EA.EN.V...F.P.....PIEVTLEVHENVIFFENPMV-a...................................................
B4QJL2_DROSI/215-475               .........................................................................................KVQVPLSVLCDCITIRCVHTNFDHHSSH.AKS......Y..EPLTVESiym....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NNMN........RR.REEYEELMQli..............aeRTEQAAKEAKFG----KG........GDGDKHPK-IV.I...PK.T........PKLVPLVPQGMYPDIFKEFLFREEDQYKKFLSTYfHP.DNLSL.TPEEVNLRECIIVGGIYNISFVRRPDQTQF....EKFNIVLHEDGRVLRVTP.QVVakp..........................dnrK---SRL.T.EYTRmtl...............gtsqMK.LS.EE.E...L.P.....FFVVTVQLPPHLCRWGKPEVC....................................................
G1PKM3_MYOLU/464-671               ...............................................................................wktdgisnvv----------YKSEERIITFNLDTLGPV.TLI......Q..DAHINMP...........---..--..---YQSWELRP..LDEN......KVL.LTVT........TV.FAEIQIQIK..................EGLCMLAS----------........LNVGDKKPLSI.L...EG.K........WMTPIYFIITLQEAGLNIFPTEYSHFYVAT----.NC.KVPLV.--EMKAYRQMAVLSSAFAFGWSKWNMQC--....GSEKVIFKVSECLTKEQE.CIQdp............................twTLLMFSG.N.RAQR......................LK.ID.ED.S...E.A.....F--------------------sealke..............................................
B5MDN1_HUMAN/242-460               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B5RID9_DROME/616-724               .........................................................................................WTTEFILESSFNKESKVVIVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNh....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYVHRPFKYID.I...DK.P........IST-------------------------------.--.-----.------------------------------....------------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------hvstsir.............................................
Q7KTX4_DROME/797-1013              .........................................................................................WTTKYVKDVVIDRETNSITFKTDRLGLL.GLA......F..KRYEHFP...........---..--..---FRNWSLQP..NEENp....dEII.LCVD........TF.HVRIFFYIT..................-----CKGVRGYVTDLSK........GYTAKPIKYLE.I...VE.P........ISDFRQMRQIFISKNINIFAENDASFYIENGYFS.-M.KHVAL.--EMHTYNIMALHCKLMKFYRSSWNRLA--....DRRDIIM-----------.GMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVQISENCSDKVNVIVLNY--in..................................................
Q7KTX5_DROME/802-1018              .........................................................................................WTKEYIMESQINLETNTLTFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWCLQP..SEDNp....dEVI.LSLD........TF.HVRMFFYIS..................-----ARGVRGYVTDLVK........GYTAKPVKYLE.I...VE.P........ISDFRELRKLLIERNLNIFAENDASYYITNGYFS.-I.KHIAL.--ELHTYNTMALQCKLMKFCRSSWNRLA--....QRRDIIV-----------.EMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVKISEMCSDDVNVVKLRYE-d...................................................
A8JUM9_DROME/883-1093              .........................................................................................WSTRDVHDTKFNEDKLSIQFRTGRLGIF.GFA......L..NKYSNMP...........---..--..---YQTWDLRP..DMKNp....gTII.FSFT........AS.LISLDMTIT..................KSGYTVNNFQGGSTQ---........GITDMIGKTLS.L...SE.-........------LKATLILSAVDIFPDEDAFCYTEG--SC.-E.KNYVM.--EMHCYACLSTLAQSHNFSWSRWNLLA--....GSRTAVL-----------.LVR...............................eLIEGKKV.P.YYST......................LL.VT.PL.K...T.S.....IIDCTEVSASFNAVGIPGM--ey..................................................
Q179I2_AEDAE/223-453               .........................................................................................KFQKPPSFDLKNCSMRGMWTQFDHFSDL.DPS......F..RCPISEP...........IPD..LI..ASQEMEWADRN..LLRA......QKL.QEMK........SA.REHYEVEQK.................kKELEELEAAKGGKKPTKK........KKKSKSKDKAE.V...KP.L........EAPPPVITENTTVDIDDLYVLQEQQNYERKMEQI.GP.NSLNV.GTNYINLRQHVINGGIFSIQRFEKLPQPSEl.rgDFIYTTFSDDLKLTENKF.---................................-------.-.----......................--.TC.ES.D...I.D.....LIVLNIKLPEQYFWWHSPVVC....................................................
B4J1D1_DROGR/891-1106              .........................................................................................WTTKYIKRTEYDPQSFTFKIQTDRLGIF.GFA......C..KRYEHFP...........---..--..---FRHWQLQY..NEENs....dEII.FTLD........TH.HVRIVLFIT..................-----NAGIRGYVTKLTD........EYVAKPVKYVE.I...EQ.P........ISDYRELRRRFCEKNVNIFAENDALFYIENGYFS.-V.KHLAA.--ELHVYDAFAVHCKLVKFFRSDWNRLS--....TRRNIVL-----------.CMR................................NPKDLNE.G.A-VT......................IR.VT.PN.N...S.T.....FVEVSEPCSDNLETIKLAYQ-l...................................................
B1H288_RAT/241-469                 .......................................................................................gf--EIPRILATSNVALRLLHTHYDHITPLfSTV......V..TEEKHGS...........---..IV..AENFKEEERTE..KAVP.....eENV.FTEEaad..eaeQ-.---LKAEEEre..............lsSIPEEEVKFDPTVDTVTQ........KISDPEEEESQ.T...TQ.F........ELERKLLSETVSAAQLSLIENVLE---------M.-P.ETL--.EPYEVNMCHFAPLGGVYHLEILELPPQSKP....VKGWVLA-----------.---................................EIRQEGL.Q.KFTYppe................nteEP.DP.ES.A...F.P.....PIEVTLEIHESAIFFEDPQV-v...................................................
B4Q2N1_DROYA/284-512               qislpptvylqssalrglwlnydhfsdycgsyclkharsananilrqtkrewrkrkeilqamldecgreiplseleqltqdqhsassqp----------------------------.---......-..-------...........---..--..-----------..----......---.----........--.---------..................------------------........-----------.-...--.-........-------PRERTYDVDKLYAEYEDELSKAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ...lN-ARSFI----RTITSA-.---................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
C3Z1T5_BRAFL/361-547               .....................................................................................ftdi---------KFDEENKTLSFKTNTFGLL.TVI......Q..DSHLNMP...........---..--..---FQSWEIRP..RGNN......SAL.FTII........AA.IVELEIEIK..................D-----DKC--C---LSQ........PEDTPELD--H.L...RK.K........WLAPKDLVKALKAAGVNIFPEPDSSKFVSM---T.-K.KDEEA.--EMLTYRCMAMTLPAFAFSWSKWNAEAGE....DRI---------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------vmqaaehledepvneddwccyvqsvrrakklkin..................
B4L9E9_DROMO/50-321                .........................................................................................QVQIPLSVLCDNLTLRCVHTLFDHLSEE.AKS......Y..EQVIDGVvni.....nggIMD..ID..DCLVNEWLMQL..NLVD......KII.SALE........QR.LTEYEQYTAev.............aqkEAAARLVEKRANKSRSPK........DAKSKRSEQRL.S...KR.I........LREPEMIPEGMFPDPLQRFIEQEQQEFDDFLNQFlNP.QNLKL.APDEINLRQYNILGGLYSMHFVRKPMHKEF....EKFNITLHEDGRILYTQQ.DVRadv.........................gsrrSTRLKSR.F.NYTQames.............penrhLK.LA.PD.E...V.S.....YFCVTFRLPKMLCLFGEPVVC....................................................
Q8MRS7_DROME/64-326                ........................................................................................t-IQLPLSVLCDNLTLRCVRTFFDPLSHL.AKS......F..ELVIDSSvip.....ncgLVD..IA..DSVMSEWMTQM..DIQE......DLV.VKME........TE.MRAYNEAIA.................fI-----------AQAEAK........EKRKSQKKKIA.I...PK.P........PKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYfHP.GNINL.LPSEVNLRRFIILGGIVSLVFVGKAKHASY....EKFNITLHEDGRVLRKSL.NILdesst......................eecsmQ------.-.---PskldigtdimrdtevgeaskipLH.LE.PD.E...L.P.....YYFLTFKVPNHLCLWGEPIVC....................................................
B4IAI4_DROSE/198-440               .............................................................................yrvlsmqdaymd-----------------LHMDFDNISQN.AKS......F..ETAVQASvny....pnagIVD..IE..NSVVNEWHMQL..EIQE......ETL.NLML........SR.RREYEDMMEli..............aeKTEQAAKAA-------KQ........TDPDKAVK-II.I...PK.A........PKEPPFVATGMYPDTYDDFLRIEESQYSGY----.--.----L.--DEINLRDYIMLGGIYSIMFIRRPDQTQF....EKFNIVLHEDGRVVHKLT.EMKadipve...................avrksniGRKTRET.Y.RGTK......................IK.LE.DD.E...L.P.....YFIVTLQVAADLCKWSEPLVC....................................................
B4GUM0_DROPE/249-515               ........................................................................................s-VQMPLSVLRDCLTLRCIHTKFDNYSPN.AKS......Y..ELLVTESpty....ptagIVD..IE..ASAENEWRMQL..EIQK......EIL.EEML........VK.RQLYEELIE..................LINAKNE-----QAARES........KGADRKAQKAA.I...PK.F........PKEQPIVPPGMVPDIYQEFVKREKTQYQSFLEEVyHP.NALNL.TYDEINLRECIMLGGIYSIMFVGRPAQTQF....EKFNIILHEDGRALLTMP.EVVavldkp....................edslraS------.-.---Alsaarsshf....rltledignMR.LD.PD.E...L.P.....YFIVVLDLAPELCLWGEPKVC....................................................
F5HMV4_ANOGA/872-1099              .........................................................................................WSTMPIRNQSYDPERRLLTFTTDRLGVY.GLA......A..RKYCNIP...........---..--..---FVHWDMRR..HGRIa...nlTTA.LTLT........TK.SLQIVFYVT..................-----AQGYRLALQEHAK........KQTKKLFL-EE.A...PA.PevlppgdgTFTLDELEKFLQRMNVHLFPQVDTCFYVPDVERAaSP.KHPSM.--ESHNLRCLGVFCLTHNFQSCLWNRYA-L....RRTALVL---GREL----.---................................-IEGRNE.P.EFGT......................VM.IT.PL.K...S.Q.....FVEVEELCSDALEQI------llayhp..............................................
Q8MRS7_DROME/650-866               .........................................................................................WTTEFILESSFNKESKVVIVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNh....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYVHRPFKYID.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHIYDAIAVHGKLMKFSRSQWNRLA--....KDRDLVL-----------.CLQ................................NTRDIHD.G.SEVT......................VR.VT.PE.V...S.T.....FVDVSELCSDDTKVIKLNYK-s...................................................
F1R213_DANRE/240-472               .................................................................................felpkpla---------VIEVAVRILHTRYDHLSHH.SER......E..QLQKRRS...........---..--..---MMEAILTQ..NTES.....sAAV.HNGKmegerdesES.SKQVEECHS.................vRSESRKRSA-VSVISAKE........GRKSSSVK--L.L...EE.G........ESQMEEITTTLESDQHDPYPSPAE----------.PV.TDTDV.--HIVDLQQFTPLGGVFYFDLFHMPPQSRT....VKGWEMR----ELLDTGL.QVFp..............................yPTEQSRI.Q.SSTS......................VK.LD.EH.S...N.TtvaslPVGVTVALPHSVLFLEDP---qva.................................................
G1QZI0_NOMLE/299-516               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HLV......S..TPSKEHT...........---..--..---SAVTELVK..DIKNv....eKAIsKEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVLAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................taeDF.ET.EN.A...F.P.....PIEVTLEVHENLIFFADPMVV....................................................
F5H6T6_HUMAN/177-395               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
B3NIU3_DROER/759-975               .........................................................................................WTTKYIKETVIDRATNRITFKTDRLGLL.GLA......F..KRYEHFP...........---..--..---FRNWSMQP..NEENp....dEII.LCVD........TF.HVRIFFYIT..................-----CKGVKGYVTDLSK........GYTANPVKYLE.I...AE.P........ISDFRQMRQLFISKNINIFAENDASFYIENGYFS.-M.KHMAL.--EMHTYNIMALHCKLMKFYRSSWNRLA--....PRRDIIL-----------.GMK................................IAKDNSD.Y.SEVT......................MR.IT.PE.K...T.T.....FVQISENCSDKVNVIVLSYN-n...................................................
B3NT98_DROER/284-512               .....................................................................................qisl----PPTVHLQSSALRGLWLNYDHFSDY.CSS......Y..CLKHARS...........---..AN..ANILRQTKREW..RKRK......EIL.QAML........DE.CGREIPLSE..................-----LEQ-------LTQ........DQHSASSQ---.-...--.-........------PPRERTYDVDKLYAEYEDELSKAHRRAI.GP.EAYGM.LETDVNLRKYRIIGGVYCIDFLETPQQDKQ...lN-ARSFI----RTITSA-.---................................NSLVHKE.Y.YQTYkppppvlpgv..rrlpeeieaeMR.MI.EA.A...L.D....kLALVTLQLPDSVIWFEPPVAC....................................................
B4PE87_DROYA/250-412               .........................................................................................KVQVPQSALWDCLTIRCVHTSFDHQSPQ.AKS......Y..EPLTVDSafm....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NIMN........RR.RAEYEELMQli..............veRTEQAAKEAKFG----KG........GDGDKRPK-IV.I...PK.V........PKAVPLVPQGMYPEIFNEFLFREEDQYKQNKDSI.--.-----.------------------------------....------------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------lssycyncsnfdl.......................................
G7PK19_MACFA/236-454               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SSATELVK..DDVEnv..ekAIS.KEVE........EE.SKQQEKQSH..................LIQEEKLKVEEEQDDIEV........KMSSAEEE-SE.A...IK.C........ELEMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.ENDMVDLFQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFENPMVV....................................................
CASC1_HUMAN/236-454                .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEYT...........---..--..---SAVTELVK..DDVKnv..ekAIS.KEVE........EE.SKQQERGSH..................LIQEEEIKVEEEQGDIEV........KMSSAEEE-SE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
H3J7R1_STRPU/490-674               ......................................................................................fhd--------VKFEQEERLLSFKTIKFGPL.ACI......Q..DKHINMP...........---..--..---FQSWELFP..LGTN......HAR.FTII........AA.ILEVEFEIK..................D---HLCCFRQ------A........GDGERKPELES.I...SN.K........WMEPPQLIETMKKAGVNVFPEEDSKKYVSVCDKD.--.--EQT.--EGAAYDQMALTASHFAYSWSKWNAETSP....DKI---------------.---................................-------.-.----......................--.--.--.-...-.-.....---------------------illgceklvpepvkdedwqvlltskkqts.......................
B2KFB8_MOUSE/228-456               .......................................................................................gf--EIPRILATSNVALRLLHTRYDHITPLfPIA......V..TEQNQNPvg.......aeQVN..VE..ESTEKAMTEEK..LFTE.....eKAA.NEDE........QP.KAEQERELN..................LVQEENKYEAIENTVLQR........TSDSE-GEDSQ.T...TQ.L........ELEMKLLSEAVLAAQQRLVENVVE---------L.-P.EASQA.--YKVDLCHFSTLGGVYHLDVLELPPQCKP....VKGWVLV-----------.---................................EILQEGL.Q.RFIYpp.................dttEE.PD.PDvT...F.P.....PIEVTLEIHKSVIFFERPRV-v...................................................
B4IUJ4_DROYA/216-476               .........................................................................................KVQVPQSALWDCLTIRCVHTSFDHQSPQ.AKS......Y..EPLTVDSafm....pnagLTD..ME..ESVVGEWLMQN..DIQE......ETL.NIMN........RR.RAEYEELMQli..............veRTEQAAKEAKFG----KG........GDGDKRPK-IV.I...PK.V........PKAVPLVPQGMYPEIFNEFLFREEDQYKQFLRTYfHP.DNLSL.TPEEVNLRECIIVGGIYNISFVRRPDQTQF....EKFNIILHEKGRVLEVIP.QVV................................AQKDNRK.S.RLTEytrmt............lgtsqMK.LN.DD.E...L.P.....FFVVTLQLPPDLCRWGKPEVC....................................................
H0YJM7_HUMAN/104-291               ........................................................feeviekskvvlnlieklkfilletppcdlqdk----------------------------.---......-..-------...........---..--..-----------..----......---.----........-N.IIQYQESIL..................-QLQELLHLKFGVATEIL........LKSSAE-EESE.A...IK.C........EREMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.EDNVVDLCQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteEF.ET.EN.A...F.P.....PIEVTLEVHENVIFFEDPVVV....................................................
E2BYG3_HARSA/244-498               ........................................................................................t-VKMPTDIDCYCMAIRALWVKYDHYSDR.ATS......Y..VMPELPReye.....sghIMN..FL..AYCQSEYDSKL..KIRE......EQA.EGRR........LR.LEEKKAILE..................K-----MEHPPEPEPTKS........DRKGKQQKKLG.VqtkPE.P........IQEPERLPYLPVPDEIILQRDEETKKEIRKLLFM.--.---RC.EKTEINLRKYKILGGVIHIDLIYQPPQPKD....MGRDVLL----TTLQIPK.ELKfvpfskpy................kapppapdS----ER.T.PEVIe...................aeMK.AL.ET.A..mE.A.....LALITLKLPSSIIWFEPPLV-a...................................................
E1NZC6_DROME/517-733               .........................................................................................WTTEFILESSFNKESKVVIVKTDRLGHF.GFA......Y..RRYAHFP...........---..--..---FRHWELEK..NEQNh....dEII.LTLD........TY.HVRVVFFIS..................-----KDGIRCHAIDIPK........EYVHRPFKYID.I...DK.P........ISDFVELRKRLQDMNLNVFAELDACFYIDQGYFS.-Q.KHLAA.--ELHIYDAIAVHGKLMKFSRSQWNRLA--....KDRDLVL-----------.CLQ................................NTRDIHD.G.SEVT......................VR.VT.PE.V...S.T.....FVDVSELCSDDTKVIKLNYK-s...................................................
F6SGY4_MACMU/236-454               .......................................................................................gf--EIPRILATSDIAVRLLHTHYDHVSAL.HPV......S..TPSKEHT...........---..--..---SSVTELVK..DDVEn...veKAIsKEVE........EE.SKQQEKQSH..................LIQEEKLKVEEEQDDIEV........KMSSAEEE-SE.A...IK.C........ELEMKVLSETVSAAQLLLVENSSE-----KPDFF.--.-----.ENDMVDLFQFTTLGGVYHLDILELPPQCKP....VKGWMIV-----------.---................................EILKEGL.Q.KYTYppe................tteDF.ET.EN.A...F.P.....PIEVTLEVHENVIFFENPMVV....................................................
E2BYG3_HARSA/507-716               .........................................................................................WSTQDVHDIKYNEEKQTITFRTGRLGVH.GLA......A..FKFINIP...........---..--..---FQTWELKP..EMGRna..rgGVV.LNVS........AA.IVQAEFIVR..................EDLVCLNSLA-------G........GMSTAIK---E.I...LG.E........YMKLYFLVEKMRDAGCDLFPERDAFSYVKSLP--.-V.KHPVT.--EKHLRECMALLCTAYTFSWSRWSANR--....NCREIVV---------QFkELH................................-GCLAKE.Q.TNAT......................LL.VT.PS.R...T.M.....VVACTEVSSEFSD--------vpvd................................................
H9IEN6_ATTCE/587-794               .........................................................................................WSTQDVHDIKYNEEKQTITFRTGRLGIH.GLA......T..FKFINIP...........---..--..---FQSWELKP..EISRnv..rgGIV.LNVS........AA.IVQAEFIVR..................EDLVCLNSLAG-------........---GMSTALKE.I...IG.K........YMKLHILIEKMRDAGCDLFPERDAFSYVKALP--.-I.KHPIT.--EKHLRKCMALLCTAYTFSWSRWNASR--....HSREIVI---------QF.---................................KELHGCV.A.KERTn...................liLL.VT.PL.K...T.M.....TVSCTEVSTEF----------ssvp................................................
B4GUM1_DROPE/773-989               .........................................................................................WTTKHIVGTTFDREANTITFRTDRLGIF.GLA......F..KRYEHFP...........---..--..---FRDWSLQP..NEENp....dEII.LQLD........TY.HVRVFLYIT..................-----AKGVRGYATDLGS........AYTAKPVKYLE.I...VE.P........ISDFRDFRKIFLEKNINIFAENDASFYIGKGYFS.-I.KHVAA.--ELHTYDVMALHCKLIKFYRSSWNRLA--....SRRDIIV-----------.GMK................................NAKDPSD.Y.SEVT......................MR.VT.PD.S...A.K.....FVKISELCSDDVNVIRLEYE-n...................................................
#=GC seq_cons                      ...........................................................................................ph.h..hp.shth+hlphchD+lu.h.shu......h..p.h.phs.......................hppaphp...s.pp......phl.hphp........pt.hhphp.hhp........................ttht....t.tt........thsst..c..p.h....c............p.t.L.pthhssshplF.pp-t..hhph...h....cphth...p.hshcphshlGulaphshhchs.ps......t+tphll.............h.................................p.ht.t....t.sh......................hh.hs..s.t...h.s.....hltlT.phspplhhht.shh.....................................................
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