GenomeNet

Database: Pfam
Entry: ChitinaseA_N
LinkDB: ChitinaseA_N
Original site: ChitinaseA_N 
#=GF ID   ChitinaseA_N
#=GF AC   PF08329.8
#=GF DE   Chitinase A, N-terminal domain
#=GF AU   Fenech M
#=GF SE   Pfam-B_1049 (release 18.0)
#=GF GA   21.20 21.20;
#=GF TC   21.20 21.20;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Chitinase_A_N-terminal_domain
#=GF RN   [1]
#=GF RM   7704527
#=GF RT   Crystal structure of a bacterial chitinase at 2.3 A resolution. 
#=GF RA   Perrakis A, Tews I, Dauter Z, Oppenheim AB, Chet I, Wilson KS,
#=GF RA   Vorgias CE; 
#=GF RL   Structure 1994;2:1169-1180.
#=GF RN   [2]
#=GF RM   9377712
#=GF RT   Evolution of immunoglobulin-like modules in chitinases: their
#=GF RT   structural flexibility and functional implications. 
#=GF RA   Perrakis A, Ouzounis C, Wilson KS; 
#=GF RL   Fold Des 1997;2:291-294.
#=GF DR   INTERPRO; IPR013540;
#=GF DR   SCOP; 1ctn; fa;
#=GF CC   This domain is found in a number of bacterial chitinases and
#=GF CC   similar viral proteins. It is organised into a fibronectin III
#=GF CC   module domain-like fold, comprising only beta strands. Its
#=GF CC   function is not known, but it may be involved in interaction
#=GF CC   with the enzyme substrate, chitin [1,2]. It is separated by a
#=GF CC   hinge region from the catalytic domain (Pfam:PF00704); this
#=GF CC   hinge region is probably mobile, allowing the N-terminal domain
#=GF CC   to have different relative positions in solution [1].
#=GF SQ   78
#=GS Q12MA8_SHEDO/27-159         AC Q12MA8.1
#=GS A0A0M2HRY2_9MICO/2011-2092  AC A0A0M2HRY2.1
#=GS A5I5R7_CLOBH/41-169         AC A5I5R7.1
#=GS D4ZGM8_SHEVD/23-155         AC D4ZGM8.1
#=GS B1KH85_SHEWM/23-155         AC B1KH85.1
#=GS A0A089KUJ2_9BACL/1957-2050  AC A0A089KUJ2.1
#=GS F7YT96_VIBA7/30-167         AC F7YT96.1
#=GS A0A0N0XN42_9NEIS/208-317    AC A0A0N0XN42.1
#=GS A8T3S3_9VIBR/29-166         AC A8T3S3.1
#=GS Q87K43_VIBPA/20-157         AC Q87K43.1
#=GS E3BJE0_9VIBR/20-157         AC E3BJE0.1
#=GS F0LZ75_VIBFN/20-157         AC F0LZ75.1
#=GS A0A0A7EGV5_9GAMM/19-155     AC A0A0A7EGV5.1
#=GS F5SJU6_9BACL/37-125         AC F5SJU6.1
#=GS A0A0D8MVN0_PHOLE/20-157     AC A0A0D8MVN0.1
#=GS K4KHW4_SIMAS/20-121         AC K4KHW4.1
#=GS C9ZB10_STRSW/452-533        AC C9ZB10.1
#=GS F2LL47_BURGS/39-185         AC F2LL47.1
#=GS A6D2X0_9VIBR/20-157         AC A6D2X0.1
#=GS A8AIM7_CITK8/22-155         AC A8AIM7.1
#=GS E1SNM7_FERBD/23-154         AC E1SNM7.1
#=GS F9T7Y1_9VIBR/20-157         AC F9T7Y1.1
#=GS C9ZB10_STRSW/360-447        AC C9ZB10.1
#=GS A5I5R8_CLOBH/654-738        AC A5I5R8.1
#=GS C9P7N8_VIBME/22-159         AC C9P7N8.1
#=GS A0A0L7LKN3_9NEOP/15-146     AC A0A0L7LKN3.1
#=GS Q9KND8_VIBCH/20-157         AC Q9KND8.1
#=GS A0KGX3_AERHH/23-156         AC A0KGX3.1
#=GS H9JGR2_BOMMO/16-147         AC H9JGR2.1
#=GS Q84AP8_SACD2/30-125         AC Q84AP8.1
#=GS Q7PC53_SACD2/682-792        AC Q7PC53.1
#=GS Q5E4F3_VIBF1/23-163         AC Q5E4F3.1
#=GS I0DQR8_PROSM/23-156         AC I0DQR8.1
#=GS A0A0D8PPY9_9GAMM/160-239    AC A0A0D8PPY9.1
#=GS K8WID4_9ENTR/23-156         AC K8WID4.1
#=GS A0A0D8QB86_9GAMM/22-154     AC A0A0D8QB86.1
#=GS A0A0N1ES29_9GAMM/20-157     AC A0A0N1ES29.1
#=GS A0A0F6TPR0_9GAMM/27-135     AC A0A0F6TPR0.1
#=GS K2JN34_9GAMM/22-158         AC K2JN34.1
#=GS F9R9Z0_VIBSN/20-157         AC F9R9Z0.1
#=GS F2JIU1_CELLD/445-532        AC F2JIU1.1
#=GS A0A0F4R071_9GAMM/21-157     AC A0A0F4R071.1
#=GS A0A0F5AQY0_9GAMM/21-160     AC A0A0F5AQY0.1
#=GS A0A0C5WEE2_9GAMM/21-153     AC A0A0C5WEE2.1
#=GS A0A0F4PQG2_9GAMM/20-156     AC A0A0F4PQG2.1
#=GS K4KFR0_SIMAS/82-183         AC K4KFR0.2
#=GS A0A0A2U6P0_9BACL/1558-1644  AC A0A0A2U6P0.1
#=GS U4KA43_9VIBR/20-157         AC U4KA43.1
#=GS A4CD88_9GAMM/21-157         AC A4CD88.1
#=GS A0A0M2H8W4_9MICO/1721-1799  AC A0A0M2H8W4.1
#=GS H2IRU5_RAHAC/23-155         AC H2IRU5.1
#=GS A0A097B053_9VIBR/20-157     AC A0A097B053.1
#=GS K7RS87_PROA4/1209-1289      AC K7RS87.1
#=GS F7NXL7_9GAMM/43-154         AC F7NXL7.1
#=GS A0A0A2UDL7_9BACL/753-839    AC A0A0A2UDL7.1
#=GS F7NXL7_9GAMM/236-336        AC F7NXL7.1
#=GS B7VTG0_VIBTL/20-157         AC B7VTG0.1
#=GS C6D3X7_PAESJ/1814-1912      AC C6D3X7.1
#=GS A0A0F5ZXX0_9GAMM/24-164     AC A0A0F5ZXX0.1
#=GS O91465_GVCPM/18-153         AC O91465.1
#=GS A0A089IKZ4_9BACL/925-1020   AC A0A089IKZ4.1
#=GS A0A0M9VMK2_9MICO/1172-1260  AC A0A0M9VMK2.1
#=GS A8G807_SERP5/23-156         AC A8G807.1
#=GS G6D3W1_DANPL/75-206         AC G6D3W1.1
#=GS A0A0F6ACA3_9GAMM/29-165     AC A0A0F6ACA3.1
#=GS A0A0D8PPY9_9GAMM/254-351    AC A0A0D8PPY9.1
#=GS A0A0F6A587_9GAMM/20-155     AC A0A0F6A587.1
#=GS A0A0F5VG93_9GAMM/23-163     AC A0A0F5VG93.1
#=GS A0A0F4NNQ7_9VIBR/20-157     AC A0A0F4NNQ7.1
#=GS A6AUU6_VIBCY/20-157         AC A6AUU6.1
#=GS I1E2R9_9GAMM/160-265        AC I1E2R9.1
#=GS Q7MGC4_VIBVY/44-181         AC Q7MGC4.1
#=GS A0A0F6AAG1_9GAMM/21-157     AC A0A0F6AAG1.1
#=GS A0A0F4QMJ4_9GAMM/20-156     AC A0A0F4QMJ4.1
#=GS A0A0F0LB63_9MICO/375-469    AC A0A0F0LB63.1
#=GS I1E2R9_9GAMM/23-143         AC I1E2R9.1
#=GS A8T9I8_9VIBR/10-140         AC A8T9I8.1
#=GS Q8B9D6_NPVR1/16-147         AC Q8B9D6.1
Q12MA8_SHEDO/27-159                    .......................................AAAPGKPSLA.WG..E..TQFAI..IDVNQSAT.AYNQLVTV.KDAAAVSVSWSLWSGNVGERAQ.....VL......LNGNQVW.......EGASS......ASGTA.....NFN.V..N....EGGRYQMQVQLCNS..EG....CTA.SD..PKTI.IVADTDGSHLLPLNAPLLENNRPYTNH-s..............
A0A0M2HRY2_9MICO/2011-2092             ...............................ngdrdgsy----------.--..-..-----..--------.--------.------TVTTDLWWGTNGTTYR.....LF......ENGVQIDeq...alA-AASp...naQHVTT.....AVS.G..R....AAGTYSYVAELSNA..AG....ATR.SK..AVTV.TV--------------------------r..............
A5I5R7_CLOBH/41-169                    nkiqlksnsnsyvlnnskvldaqtsapsdfqlskdnwdg----------.--..-..-----..--------.--------.--SPNYTISMDMWYGTNGDAWK.....LY......ENGKLVHevk.lvnNSPNA......QHAEI.....KLT.N..K....SNGTYTYTAELINA..AG....VTK.SK..NTIV.----------------------------hevtkndapidvplp
D4ZGM8_SHEVD/23-155                    ......................................a-SVPGKPTIG.WG..E..TNFSI..IEIDQAAT.AYNQLVTV.KDAAQVSVNWNLWSGELGDSAK.....VL......FDGVEVW.......SGPST......ASGAA.....TFS.V..S....HGGRYQMLVELCNA..EG....CTR.SA..AKEI.IVADTDGSHLLPLETQLGENNKPYANK-s..............
B1KH85_SHEWM/23-155                    ......................................a-SVPGKPTIG.WG..E..TNFSI..IEVNQAAT.AYNQLVTV.KDAAEVSVNWNLWSGELGDTAK.....VL......FDGVEVW.......SGSST......ASGSA.....TFN.I..S....QGGRYQMQIELCNA..QG....CTL.SD..AKEI.IVADTDGSHLLPLDTQLGENNRPYVNK-s..............
A0A089KUJ2_9BACL/1957-2050             ...................................rdgd----------.--..-..-----..--------.--------.-----YTITMNLWWGNNGTRFK.....LY......EDGKLVKevs.lsdQSPAA......QSVQI.....DIS.G..K....KNGTYIYTGELINA..LG....ITK.SA..PLTV.NVTDA-----------------------spgqavlsndnwd..
F7YT96_VIBA7/30-167                    .......................................MAAPATPSVDvYG..S..NNLQFskVELAMESTaGYNQMVKY.YDQAPIAVKFNQWSGTTGNTYK.....IY......FDGAQVA.......TGPIT.....gSQTTA.....NFS.Y..A....QGGVYQMAIEACDA..TG....CSK.SA..PVEI.TIADTDGSHLKPLVMNIDPNNKTYTTD-k..............
A0A0N0XN42_9NEIS/208-317               .........................stpeiewlpsvstg----------.--..-..-----..--------.--------.---EPVELTWHMWWGVPGHYWQ.....VL......DQGRVVYesttfneNTDHT......QSAST.....QLR.D..L....AAGTHALTVRLCSK..LD....CAD.SEayPLEV.MLAGVDAAALPKL---------------allgkv.........
A8T3S3_9VIBR/29-166                    ......................................n-AVPAAPSIDlYG..S..NNLQFskIELAMETTsGYYDMVKY.HELAKINVKFNQWSGTSGDTYN.....IY......FDGVKVA.......TGAIT.....gSQTLA.....SFE.Y..G....QGGLYQMEIEACDA..SG....CAK.SA..PAEI.TIADTDGSHLPPLTMNIDPNNKTYSTD-p..............
Q87K43_VIBPA/20-157                    ......................................v-AAPTAPSVDmYG..S..NNLQFskIELAMETTsGYYDMVKY.HDQAKITVKFNQWSGTPGDTYN.....IY......FDGVKVA.......TGAIT.....gGQTTA.....TFD.Y..G....QGGLYQMEIEACDA..TG....CSK.SD..PAEI.TIADTDGSHLKPLTMNVDPNNKTYNTD-p..............
E3BJE0_9VIBR/20-157                    ......................................s-AAPSVPTIDvYG..S..NNLQFskIELTMDSTsGYYDMVKY.SDEAEVSIKFTQWSGDPGDSYK.....VY......FDDVEVA.......SGAIS.....gNQTTA.....IFS.M..A....QGGRYKVAVEACDS..TG....CSR.SA..EQQL.IIADTDGSHLEPLNMNVDPNNKSYDTD-p..............
F0LZ75_VIBFN/20-157                    ......................................l-AAPAAPSIDvYG..S..NNLQFskIELAMETTaGYNQMVTY.HDEAPISITFNQWSGETGNTYK.....IY......FDGEEVA.......SGPIS.....gSQTTA.....SFT.Y..S....KGGLYQLEVAACDD..SG....CST.SA..PVEL.TIADTDGAHLKPLTMNVDPNNKTYTTD-a..............
A0A0A7EGV5_9GAMM/19-155                ......................................f-AAPSAPSIS.WE..D..QKYSF..VDVNIDGQgSYKSLVTR.KDVVDIAIKWNSWSGDGGDGYK.....VK......FDGVVVN.......EGSLPa...gtKSGTI.....TFP.Y..T....KSGRHQMTVELCEG..TT....CAA.SA..PKAI.VIADTDGGHLDPLPMNVDPNNGNYGT--sp.............
F5SJU6_9BACL/37-125                    ...............................vlnhthwn----------.--..-..-----..--------.--------.-NDGNYKIEMNMWWGNNGSSWK.....LY......ENGKLIH.......EEDLK.....dNSPQAqyafkEFT.K..K....AGGTYKYQAELINS..HG....ITE.SN..EVII.KV--------------------------pge............
A0A0D8MVN0_PHOLE/20-157                ......................................f-AAPTAPSIDmYG..S..NNLQFskIELAMETTsGYNDMVKY.HDKAKINVKFNQWSGNSGDTYN.....IY......FDGKKVA.......SGPIK.....gSQTTA.....SFE.Y..E....QGGLYQMEIEACDE..TG....CAK.SA..PAQI.TIADTDGSHLPPLAMNVDPNNKSFDTD-p..............
K4KHW4_SIMAS/20-121                    ......................faapgtpniawleatqq----------.--..-..-----..--------.--------.-SGSAIKVDWNMWWGENGTTWT.....LY......NNGNVQC.......QGSLTpngqnqQSGS-.....CTS.A..Y....PAGQNKLQVALCNT..SG....CTD.GN..TVTI.NVV-------------------------nggtvnq........
C9ZB10_STRSW/452-533                   ..............................nwdkdgtft----------.--..-..-----..--------.--------.-------ATANLWWGTNATSYT.....FY......LDGAVVG.......EGQLA.....aDSPNA....qSPQ.V..AlsgvPKGKHSLKVVLTNA..RG....STE.SD..PVDV.TVA-------------------------...............
F2LL47_BURGS/39-185                    ......................................f-AAPGAPALKaWEitSkpHGFVQ..IELDKAGAvPYKDLVRI.NKAVDVPLPFDIYYNGTAVKAL.....AV......VDGVADEasa.ismTGTGG.....tQKGSV.....VAH.V..T....RPGKKQMQVRVFDD..KG...aFTD.SA..PLEV.MVFDTTPELADDLPDNADKANRPFRN--ts.............
A6D2X0_9VIBR/20-157                    ......................................n-AAPAKPSIDvWG..S..NNLQFskIQLAMETTsGYDQMVQY.NDLAEIKITFNQWSGTTGDTYN.....IY......FDGNKVA.......TGPIT.....gSQTTA.....TFG.Y..G....QGGLYQMQVEACDA..TG....CSK.SA..PMEL.VVADTDGSHLAPLTMNIDPNNKSYNTD-p..............
A8AIM7_CITK8/22-155                    .......................................AAAPGTPSIT.SG..N..DKFAI..VEVDQAAQ.DYNNLVKVhNDGVDVKVEWNVWSGDAPTSAK.....VL......LDGKTVW.......SGAGS......AAGSA.....TFK.V..K....KGGRYQEQVELCNT..SG....CTK.SA..SKLI.IVADTDGSHLLPLNTTMKENNKTFAQH-t..............
E1SNM7_FERBD/23-154                    .......................................AAIPAKPSIA.-G..D..THFAV..IEVDHGAT.SYNQLINV.KPAAEVSVSWSLWHGELGDTAK.....VL......LDDQVVW.......QGPSA......ASGTA.....EFE.V..S....KAGRYQLTVALCNA..EG....CTS.SD..PMSI.QVADTDGSHLAPLDLQLKENNRPYTNT-s..............
F9T7Y1_9VIBR/20-157                    ......................................i-AAPTAPSVDvYG..S..NNLQFskIQLAMETTsGYNQMVKY.FDEADITVKFNQWSGTTGDTYK.....VY......FDGVQVA.......TGPIA.....gSQTTA.....SFK.Y..G....KGGLYQMTIEACDA..TG....CSV.SA..PVEV.TVADTDGSHLKPLAMNIDPNNKSYNTD-p..............
C9ZB10_STRSW/360-447                   ..................................lhdgn----------.--..-..-----..--------.--------.-----YSVKMNLWHGTPGSFFR.....LY......ENDKLVAarvpttvS--GT.....sQSVVT.....EFK.D..R....PNGTYAYRAELINS..KG....TTS.TN..TTTV.TVTDA-----------------------apgkpv.........
A5I5R8_CLOBH/654-738                   .................................wwpqdg----------.--..-..-----..--------.--------.----DYTVTMNMWWGVNADKVK.....IY......ENGVLIS.......EADLTantpqaQTHSV.....KIN.G..R....KNGKYTYYAELING..AG....ITR.SD..DLIV.NVT-------------------------esn............
C9P7N8_VIBME/22-159                    ......................................i-AAPSAPSIDvYG..S..NNLQFskIQLAMETTaGYHQMVQY.REQAPISITFNQWSGERGHTYK.....IL......FDGVEVA.......SGPIS.....gSQTTA.....NFT.Y..D....KGGRYQLQVAACDD..SG....CTT.SA..PAEL.ILADTDGSHLEPLTMNVDPNNKSYSL--dp.............
A0A0L7LKN3_9NEOP/15-146                .....................................ag--PPGKPNLG.WG..E..RVFAI..VEVNQAAT.AYNQLVTK.RDAADVTVTWNTWSGDPADKSR.....VL......LNGDEYW.......SGAGS......-ATSA.....AFK.I..K....KGGRYQMVVELCNK..DG....CAS.SD..KTEI.IVADTDGSHLPPLEWSIDEKNKPFKQT-s..............
Q9KND8_VIBCH/20-157                    .......................................MAAPSAPSVDvYG..S..NNLQFskIELAMETTaGYNQMVKY.HEEAPITLKFNQWSGVTGNTYK.....IY......FDGVEVA.......TGPIS.....gSQTTA.....QFT.Y..P....KGGVYQLVIEACDA..TG....CTK.SA..PSEI.TIADTDGSHLKPLKMNVDPNNKSYT---ipq............
A0KGX3_AERHH/23-156                    .......................................AAAPGKPTIG.WG..E..TKFAI..VEVDQAAT.SYNKLVKVhADGAPVSVSWNLWSGDVGQTAK.....VL......LDGKEVW.......SGAAS......ASGTA.....NFK.V..T....KGGRYQMQVALCNA..DG....CTL.SD..KKEI.LVADTDGSHLLPLKAPLKENNKPYVNK-t..............
H9JGR2_BOMMO/16-147                    ....................................cgp---PGKPNLG.WG..E..RTFAI..VEVNQAAT.AYNQLVTK.KDAADVSVNWNVWTGDAADKSR.....VL......LDKKEVW.......SGAGS......-ATSA.....AFK.V..K....KGGRYQMQVELCNS..DG....CSS.SE..GVEI.VVADTDGSHLRPLDYSIGEKNKPFKQT-s..............
Q84AP8_SACD2/30-125                    ...............................lpathesg----------.--..-..-----..--------.--------.---EAINVHWDMWWGENGTEWQ.....LT......DNGDLRC.......SGSLTan..gqNQQSA.....ECAaN..Y....SSGSHALQVSLCNT..SG....CSE.SN..VVTI.NVNQGA----------------------ssnvppqvs......
Q7PC53_SACD2/682-792                   ......................veqptaptiawmntsyt----------.--..-..-----..--------.--------.GSSVTVTITWNMYWGTNGNQWQ.....LW......LDGEQVYsan.lttNGQNA......QTDSK.....IIT.I..T....GAGAHSVEVKLCNQ..QDi.nvSCA.SD..SETI.TL--------------------------qggsdgatssss...
Q5E4F3_VIBF1/23-163                    .......................................AAAPGQAIIS.WM..E..TDFSI..IEIDQAAT.SYKSLVTV.KDFAEVPVTWDRWSGESAEKWR.....VL......LNGVVVHee...svSPAAS......QKAST.....TLQ.V..R....QGGQYEMTVQLCNG..SGateeCST.SA..AKSI.VVADTDGSHLDPLPMNVDPANGNYTTP-a..............
I0DQR8_PROSM/23-156                    .......................................AALPGKPTIQ.WM..D..NTYSI..VEINPNED.KYELLVTR.KEAATFNVSWDLWYGDYGTTAK.....VY......LNDQEVW.......SGPST.....sSSGQA.....SLS.I..S....KGGKYKLKVALCNG..DE....CNF.SD..VVEI.TVQDTDGSHFAPLQTQLLENNQAYKQD-s..............
A0A0D8PPY9_9GAMM/160-239               ...........................slslleathdta----------.--..-..-----..--------.--------.------TLTWDK--VEKADLYK.....IY......RDGMMVA.......QSSAT.....kSLTFK.....DIS.L..S....SETRYSYQIEACNQ..YG....CAE.EK..SATL.AV--------------------------et.............
K8WID4_9ENTR/23-156                    ......................................s-ATPGTPTIS.WG..N..SQYSI..IEVNHNAT.AYNKLVKV.KDYADVDVSWSLWNGDYGTTAK.....VL......LNDQEVW.......KGPSK.....gASGSA.....KFK.V..Y....QGGRYQMQVALCNS..DG....CSM.SA..KKEI.IVADTDGSHLLPLKTSLLENNKPYEQN-s..............
A0A0D8QB86_9GAMM/22-154                .......................................AAAPGKPTIG.WG..D..YKFSL..VELNRDEI.AYSKIVKAlHDEITVDVSWDAYSGEPATTAR.....VL......INGSEVW.......IGDGA......-AKSA.....SFK.M..N....KGGRYKMQIELSNK..DG....SVV.SD..EKLL.LIADTDGSHLEPLKTEFIENNKAYPN--tt.............
A0A0N1ES29_9GAMM/20-157                ......................................t-AAPSTPSLN.WE..P..QQYSF..VEVDLESNgSYKQLVKR.VDTVNINLQWNAWSGTGGDSYK.....VY......FDDMLVN.......EGALPa...gtKSGTI.....SFP.Y..D....KSGRHTLYIELCEA..GA...tCAR.SA..GKPI.VIADTDGGHLAPLPMDVNPNNRNIG---tkq............
A0A0F6TPR0_9GAMM/27-135                ..........gapenveirsdeaskyvlihgdvpflvpv----------.--..-..-----..--------.------KAsDDDGNFSVSWDENSGADYYQYR.....VC......EDGVCGD.......-WEQT......GANSV.....GIQ.V..N....GAGDFTVEVSACDA..SG....CSSvSS..SEE-.----------------------------lyvnpqt........
K2JN34_9GAMM/22-158                    .......................................AAAPGKPGID.WM..E..TSFAI..IEVDDAAT.AYEQLLTI.KDAADVPVAWTKYSGDGATRVQ.....YL......LNGQVVRed...siSGGAT......QTGSA.....TLQ.V..A....KGGQYQLQVALCNS..DG....CTS.SD..PKAI.TVADTDGSHLDPLVVSPQENNQPFVD--qs.............
F9R9Z0_VIBSN/20-157                    ......................................n-AAPSVPSIDiYG..S..NNLQFskIELAMETTtGYNQMVKY.LDEAAIDITFNQWSGTTGDTYN.....IY......FDATQVA.......TGPIA.....sSQTTA.....SFK.Y..A....HGGRYQMTVEACDA..SG....CSA.SS..PVEI.VVADTDGAHLPPLTMNVDPNNKSYNSD-p..............
F2JIU1_CELLD/445-532                   .............................vahncwngeq----------.--..-..-----..--------.--------.----NYSITFNMWYGVNGTSWR.....LYendkliFEESLVA.......NGTSA......QQGNA.....NMK.N..K....VAGTYTYYAELVNE..NG....VTK.SK..PITV.TV--------------------------npi............
A0A0F4R071_9GAMM/21-157                ......................................v-AAPSTPSIN.WK..P..QNYSF..VDVNIYGRgSYKQLIQA.KEVVNIAIEWNAWSGKGGDSYK.....VY......FDDEVVN.......EGQLAk...gtTRGVI.....RFP.Y..H....KSGRHELRIALCDA..SG....CAT.SA..SKPI.VIADTDGGHLEPLKLNVNPNNKKYDTD-p..............
A0A0F5AQY0_9GAMM/21-160                ......................................v-AAPSTPSLD.WK..P..QNYSF..VEVDEYGRgSYKDLVQR.VDEVQIEIKWNAWSGDGGDSYK.....VY......FDDQVVN.......QGTLPa...gtKSGVV.....TFP.Y..D....KGGRHQLKLALCEGgvDG...qCAT.SA..AKPI.VIADTDGVHLDPLPMNVDPNNNDYPKQ-p..............
A0A0C5WEE2_9GAMM/21-153                .......................................AAAPGAPTID.WG..E..HTYAL..VELNRDAS.SYEDIVVGiHDTVTVTVSWQSWSGDPADTAK.....VK......LDGNTVW.......TGSGS......-VKSA.....TFD.V..S....KGGVYDMTVELCNA..DG....CSE.SG..SVKL.TIADTDGSHLAPLVPVLQENNKPYTNK-s..............
A0A0F4PQG2_9GAMM/20-156                ......................................v-AAPSTPSLN.WE..P..QEYSF..VEVDLEGTgGYKSLVRR.QDQVNINIEWNAWSGDGGDNYK.....VY......FDDQVVN.......SGALPa...gtKSGVI.....TFP.Y..D....KAGRHTLYVELCEG..TV....CAR.SD..GKPI.VIADTDGAHLAPLPMDYDPNNKDY----glkq...........
K4KFR0_SIMAS/82-183                    ..........................aapaiawlgdqss----------.--..-..-----..--------.--------.---TSFPLSWNLWWGENGTVWK.....VK......DNGAVIHtqs.iaaNSPNA......QSASA.....TIK.V..T....GTGSRSLVVELCNS..DGanevCTP.SS..AVTV.NVS-------------------------ggvtdpgc.......
A0A0A2U6P0_9BACL/1558-1644             ..................................adgty----------.--..-..-----..--------.--------.------TITMNMWWGNNGTQYK.....LY......ENGELIDtqk.ltaSSPSS......QKAST.....NIS.G..R....VNGTYVYTCELINS..KG....TTE.CA..PHTV.TVRDA-----------------------apakpv.........
U4KA43_9VIBR/20-157                    ......................................l-AAPAAPTIDlDG..S..NNLKFskIQLEMQTLkGYHQMVSY.KDLADITIKFNQWSGTTGDTYK.....IY......FDGVEVA.......TGPIT.....gSTTTA.....AFQ.Y..G....KGGLYSVEVAACDA..TG....CSK.SA..PQEL.VVADTDGAHLKPLAMNVDPNNKTYNTD-p..............
A4CD88_9GAMM/21-157                    ......................................t-AAPSTPSLS.WE..D..QLYSF..VDVNIDGQgSYKSLVKR.KDQVEIAIKWSAWSGEGGDSYK.....IL......FDGIVVN.......EGQLAa...gaKTGTI.....TFP.Y..T....KSGRHQLTMQLCQG..SE....CAT.SA..AKPI.VIADTDGSHLAPLPMNVDPNNGDFNTD-p..............
A0A0M2H8W4_9MICO/1721-1799             ...................................tgsy----------.--..-..-----..--------.--------.------TVTADLWWGTNATSYR.....FL......ENGVEVG.......AGDLKaa..tpGAQRA.....TLP.VsgK....AKGTYTYTVEFTNA..AG....TTA.SA..PLKV.TVT-------------------------k..............
H2IRU5_RAHAC/23-155                    .......................................AALPGKPTLG.AD..E..TTFSI..IDINQSAS.AYNQLVTV.KNAADVTVTWNLWTGDAGQTAK.....VL......LNGAQVW.......SGPSG......ATGSA.....TFA.V..N....KGGRYQLQVALCNS..EG....CTT.SD..AKQI.VVADTDGSHLLPLTSTLKENNQPYNNK-s..............
A0A097B053_9VIBR/20-157                .......................................MAAPTAPSIDvYG..S..NNLQFskIELAMETTsGYNDMVKY.FDEADITIKFNQWSGTTGDTYK.....VY......FDGAQVA.......TGAIT.....gSQTTA.....SFK.Y..A....NGGRYQMTIEACDA..SG....CST.SA..PVEI.VVADTDGAHLAPLAMNVDPNNKSYNTD-p..............
K7RS87_PROA4/1209-1289                 .................................sgtgsy----------.--..-..-----..--------.--------.------TVTANMWWGTNATSYT.....FY......ENGKVIG.......SGDLT.....aTTPNAqvarvAVT.G..R....DAGTYTYTVTFSNA..QG....STT.SS..PLKV.VVA-------------------------g..............
F7NXL7_9GAMM/43-154                    .....................paapakpqlawqesnvsl----------.--..-..-----..--------.-------V.NGQISIPIQWDSWWGTNGNQWI.....LS......QNGVQIHsaa.ltkNGQNA......QNGSF.....TVP.V..S....AAGSYEYIVQLCNL..EGseqsCTS.SD..ARLI.QVAAGAGG--------------------dtgg...........
A0A0A2UDL7_9BACL/753-839               .................................lsegsy----------.--..-..-----..--------.--------.------TISMNLWWGNNGTSYK.....LY......ENGVLIDtq..kltD-ASPm....aQSAQT.....TIS.G..K....ANGTYTYVAELTNS..KG....TTS.SE..VLTV.KIAN------------------------avpgka.........
F7NXL7_9GAMM/236-336                   .............................nwqetslsls----------.--..-..-----..--------.--------.NGQVSIPISWSMWWGTNGNEWN.....LL......QNGTQIYsas.ltpNGSSA......QSGST.....SST.V..T....TAGTYNFVVQLCNV..QGaiknCTN.SD..SRAI.IVS-------------------------ggnaggg........
B7VTG0_VIBTL/20-157                    ......................................l-AAPTAPSIDmYG..S..NNLQFskIELAMETTsGYNQMVKY.HDKAKVDVKFNQWSGTSGNTYN.....IY......FDGVKVA.......TGPIT.....gSQTTA.....SFE.Y..G....QGGLFEMKIEACDE..TG....CAK.SA..PAQI.TIADTDGSHLAPLTMNVDPNNKSYNTD-p..............
C6D3X7_PAESJ/1814-1912                 ...................................dgsy----------.--..-..-----..--------.--------.------KITMNMWYGYNGTTYK.....LY......ENGVLVDtkq.ltdNSPTA......QTAST.....AIS.G..K....ANGTYTYTCELINS..FG....TTS.CS..PLTV.TVKDASPGKP------------------vlsndnwdnngdyk.
A0A0F5ZXX0_9GAMM/24-164                .......................................MAAPGAPIIA.WG..E..TNFAI..IEVNDAAT.AYKDLVTV.KPYAEVPVSWDRWSGEPGDTWR.....VL......LNGQVAHea...svTPSAS......QKESA.....IVQ.V..A....KGGKYDMVVELCSG..TGaaqaCTQ.SA..PKQI.VVADTDGSHLDPLPMNVDPNNGNYTTP-a..............
O91465_GVCPM/18-153                    ......................................h-SKPGTPQIR.WA..T..HKYSL..VEVNEQAQ.SYNSLVKTvHESVPVSLEWDVWSGARGDSVH.....LV......WDGQVVK.......EGSSD.....eLREQK....iVYN.V..R....KGGRSSVAVRLCDG..EG....CSD.SV..PVEV.VVADTDGSHLGRLEYEWRENNVPYQRA-p..............
A0A089IKZ4_9BACL/925-1020              ...................................sdgn----------.--..-..-----..--------.--------.-----FTVTMNLWWGNNATSYM.....LY......ENGTLIDsk..slkDVSPS.....aQTAST.....ALY.G..K....PNGTYIYTVELTNK..YG....TTK.SQ..PLTV.TIRDA-----------------------apgkpvlahdnwdgd
A0A0M9VMK2_9MICO/1172-1260             ..........................kpvvshdngdrdg----------.--..-..-----..--------.--------.----DFTVTANLWWGTNADAYD.....IL......LDGEVVD.......SGELAaatpsaQRVRV.....ELE.G..V....TAGTHELVAVFRNA..AG....ETA.SA..PVTV.TV--------------------------r..............
A8G807_SERP5/23-156                    .......................................AAVPGKPTLA.WG..N..TKFAI..VEVDQAAT.AYNNLVKV.KNAADVSVSWNLWNGDTGTTAK.....VL......LNGKEVW.......SGAST.....gASGTA.....NFK.V..N....KGGRYQMQVALCNA..DG....CTA.SD..ATEI.VVADTDGSHLAPLKEPLLEKNKPYKQD-s..............
G6D3W1_DANPL/75-206                    ....................................cgp---PGKPNLG.WG..E..RTFAI..VEVNQAAT.AYNQLVKR.NDAAQVPVTWNVWSGDPAETAR.....VL......FDGEEVW.......SGSGR......-STSA.....TFP.I..D....KGGRYQMKIELCNS..DG....CSY.SE..PTEI.VIADTDGSHLPPLEYSMGEKNKPFKQT-s..............
A0A0F6ACA3_9GAMM/29-165                ......................................a-VAPGAPKVE.WM..V..EKHSL..VTITD-SL.AYKDVV-V.APSVDVSVPWSKWTGEAGETVK.....VL......LDGQVVHsr..iltDVGSS......QSGVE.....TLT.F..T....KGGKFNLTVQLCNI..DG....CSD.ST..NNKVlVVADTAGSHLDPLPMKVND---------prfpiemtn......
A0A0D8PPY9_9GAMM/254-351               ............................slinngtrtni----------.--..-..-----..--------.--------.-------VNWNITSGA--THYQ.....VF......RNGEIIA.......DDLTDv....sFVDTA.....ATG.V..T....QNTQYQYAVAACNY..TG....CSV.PS..Q---.-TADVHTSAMDKLAINVKN---------idpntnsv.......
A0A0F6A587_9GAMM/20-155                .......................................MAAPSAPQIS.WE..P..QTYSF..VDVNLEGNgSYKQIVQA.KDVVTVNIKWNSWSGTGGDSYK.....VY......FDNQVVN.......QGPLAa...gtKGGTV.....SFP.Y..T....KSGRHTLYLEICDA..TG....CAK.SA..GKPI.VIADTDGGHLQPLTMDVDPNNAN-----ngti...........
A0A0F5VG93_9GAMM/23-163                .......................................MAAPGTPQIA.WM..E..TDYAI..VEVDQAAS.AYKSLITV.KPAAEVPVAWQRYSGETADLWR.....VK......LNGEVVFeq...siAPAAS......GAGST.....TLS.V..A....QGGQYAMTVELCSG..TGaaqaCTS.SA..ATNI.VVADTDGSHLDPLPMNVDGNNGNYTTP-a..............
A0A0F4NNQ7_9VIBR/20-157                ......................................i-AAPAAPSVDvYG..S..NNLQFskIELAMETTsGYNDMVKY.FDEADITIKFNQWSGETGDTYK.....VY......FDGVEVA.......TGPIS.....gSQTTA.....NFK.Y..G....KGGLYQMTIEACDA..TG....CSA.SA..PVDI.VVADTDGAHLKPLTMNIDPNNKSYNTD-p..............
A6AUU6_VIBCY/20-157                    ......................................n-AAPTAPSIDmYG..S..NNLQFskIELAMETTsGYNDMVKY.HELAKINVKFNQWSGTSGDTYN.....IY......FDGVKVA.......TGPIT.....gSQTTA.....SFE.Y..G....QGGLYQMEIEACDA..TG....CAK.SA..PAEI.TIADTDGSHLPPLTMNVDPNNKTYNTD-p..............
I1E2R9_9GAMM/160-265                   ........................kptfawsensvtlng----------.--..-..-----..--------.--------.-GSVSLNLAWNMWWGNNGNLWQ.....LK......QNGTVVHsas.lssATPAA......QSGST.....SVS.F..N....STGSYNFVVSLCQQ..SSdallCTD.SD..VKTV.SVVAG-----------------------sgggdg.........
Q7MGC4_VIBVY/44-181                    ......................................l-AAPTAPSIDlYG..S..NNLQFskIELAMETTaGYNQMVKY.HDQATISVKFNQWSGNTGDTYN.....IY......FDGVKVA.......SGPIS.....gSQTAA.....TFQ.Y..G....KGGLYQMEIEACDA..TG....CAK.SA..PAEI.TIADTDGSHLKPLTMNVDPNNKSYNTD-p..............
A0A0F6AAG1_9GAMM/21-157                ......................................v-AAPSTPSIN.WK..P..QNYSF..VDVNIYGRgSYKQLIQA.KDVVDIQIEWNAWSGKGGNSYK.....VY......FDNEVVN.......EGTLAe...gtTGGTI.....RFP.Y..H....KSGRHELRIALCDA..SG....CSM.SA..SKPI.VIADTDGGHLEPLKLNVNPNNKKFDTD-p..............
A0A0F4QMJ4_9GAMM/20-156                ......................................l-AAPSTPSLS.WE..P..QVYSF..VDVVLDGNgSYKDLVTA.KEQVDIQIKWNAWSGTGGDSYK.....VY......FDNQLVN.......EGVLDv...gtKSGTI.....TFP.Y..T....QSGRHTLYVELCDS..TG....CAR.SA..GKEI.VIADTDGGHLEPLPMDVNPNNRNN----gtip...........
A0A0F0LB63_9MICO/375-469               ..................................rdgny----------.--..-..-----..--------.--------.------NIEMNLWHGTPGSYYRlyendVL......VDGQQLN.......AVDVT.....sQTAST.....EFS.G..K....ANGTYTYRAELINS..EG....VTH.TS..SVTV.TVTDA-----------------------apaqpvvstdnwdr.
I1E2R9_9GAMM/23-143                    ....................aatpnapviswmptdytlq----------.--..-..-----..--------.--------.NGSVQVPLRWDMWWGSNGNKWY.....LH......KNDSVVYeaa.ltpNGQNA......QSGST.....SLS.F..T....QPGSYQLQVSLCDV..SGstehCAQ.SG..ITTI.TISGTGGSKPDPVE--------------pdpvdpd........
A8T9I8_9VIBR/10-140                    .....................................sr--KPGTPSIE.WG..D..FVYSL..TEINKSGQ.CYKDIVIArHDAVTVSVSWAVYSGEVTQ-SR.....VL......LDDVVVW.......QGTNE......--TQA.....NFE.V..S....KGGRYAMTVEVSNE..YG....SST.SN..AQEV.LVCDTDGSHLAPLATELRENNKPYKNT-t..............
Q8B9D6_NPVR1/16-147                    ......................................y-AIPGTPVID.WA..D..RNYAL..VEINYEAT.AYENLIKP.KKHVDVQVSWNVWNGDIGDIAY.....VL......FDEQQVW.......KGDAE......-SKRA.....TIK.V..L....VSGQFNMRVKLCNE..DG....CSV.SN..PVLV.KIADTDGGHLTPLEYTWLENNKPGRR--ed.............
#=GC seq_cons                          .........................................hPstPtlt.h......p.hth..lpls..st.sYpphlph.tstsslslsaNhWsGssGsoa+.....lh......h-GthVt.......sGshs......pssos.....shp.h..s....puGpYphplcLCsu..sG....Cop.Ss..shpl.slADTDGuHL.PL.hph..pNtsh....s..............
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