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Database: Pfam
Entry: ChitinaseA_N
LinkDB: ChitinaseA_N
Original site: ChitinaseA_N 
#=GF ID   ChitinaseA_N
#=GF AC   PF08329.7
#=GF DE   Chitinase A, N-terminal domain
#=GF AU   Fenech M
#=GF SE   Pfam-B_1049 (release 18.0)
#=GF GA   21.20 21.20;
#=GF TC   21.20 21.50;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Chitinase_A_N-terminal_domain
#=GF RN   [1]
#=GF RM   7704527
#=GF RT   Crystal structure of a bacterial chitinase at 2.3 A resolution. 
#=GF RA   Perrakis A, Tews I, Dauter Z, Oppenheim AB, Chet I, Wilson KS,
#=GF RA   Vorgias CE; 
#=GF RL   Structure 1994;2:1169-1180.
#=GF RN   [2]
#=GF RM   9377712
#=GF RT   Evolution of immunoglobulin-like modules in chitinases: their
#=GF RT   structural flexibility and functional implications. 
#=GF RA   Perrakis A, Ouzounis C, Wilson KS; 
#=GF RL   Fold Des 1997;2:291-294.
#=GF DR   INTERPRO; IPR013540;
#=GF DR   SCOP; 1ctn; fa;
#=GF CC   This domain is found in a number of bacterial chitinases and
#=GF CC   similar viral proteins. It is organised into a fibronectin III
#=GF CC   module domain-like fold, comprising only beta strands. Its
#=GF CC   function is not known, but it may be involved in interaction
#=GF CC   with the enzyme substrate, chitin [1,2]. It is separated by a
#=GF CC   hinge region from the catalytic domain (Pfam:PF00704); this
#=GF CC   hinge region is probably mobile, allowing the N-terminal domain
#=GF CC   to have different relative positions in solution [1].
#=GF SQ   41
#=GS A0A0C5WEE2_9GAMM/21-153     AC A0A0C5WEE2.1
#=GS Q12MA8_SHEDO/27-159         AC Q12MA8.1
#=GS A5I5R7_CLOBH/41-169         AC A5I5R7.1
#=GS K4KFR0_SIMAS/82-183         AC K4KFR0.2
#=GS D4ZGM8_SHEVD/23-155         AC D4ZGM8.1
#=GS B1KH85_SHEWM/23-155         AC B1KH85.1
#=GS A0A0A2U6P0_9BACL/1558-1644  AC A0A0A2U6P0.1
#=GS F7YT96_VIBA7/30-167         AC F7YT96.1
#=GS U4KA43_9VIBR/20-157         AC U4KA43.1
#=GS Q87K43_VIBPA/20-157         AC Q87K43.1
#=GS A0A0A7EGV5_9GAMM/19-155     AC A0A0A7EGV5.1
#=GS F0LZ75_VIBFN/20-157         AC F0LZ75.1
#=GS H2IRU5_RAHAC/23-155         AC H2IRU5.1
#=GS A0A097B053_9VIBR/20-157     AC A0A097B053.1
#=GS K7RS87_PROA4/1209-1289      AC K7RS87.1
#=GS K4KHW4_SIMAS/20-121         AC K4KHW4.1
#=GS C9ZB10_STRSW/452-533        AC C9ZB10.1
#=GS F2LL47_BURGS/39-185         AC F2LL47.1
#=GS A0A0A2UDL7_9BACL/753-839    AC A0A0A2UDL7.1
#=GS B7VTG0_VIBTL/20-157         AC B7VTG0.1
#=GS A0A089ML38_9BACL/1018-1097  AC A0A089ML38.1
#=GS C6D3X7_PAESJ/1814-1912      AC C6D3X7.1
#=GS A8AIM7_CITK8/22-155         AC A8AIM7.1
#=GS O91465_GVCPM/18-153         AC O91465.1
#=GS E1SNM7_FERBD/23-154         AC E1SNM7.1
#=GS F9T7Y1_9VIBR/20-157         AC F9T7Y1.1
#=GS C9ZB10_STRSW/360-447        AC C9ZB10.1
#=GS A5I5R8_CLOBH/654-738        AC A5I5R8.1
#=GS A8G807_SERP5/23-156         AC A8G807.1
#=GS Q9KND8_VIBCH/20-157         AC Q9KND8.1
#=GS A0KGX3_AERHH/23-156         AC A0KGX3.1
#=GS G6D3W1_DANPL/75-206         AC G6D3W1.1
#=GS H9JGR2_BOMMO/16-147         AC H9JGR2.1
#=GS Q84AP8_SACD2/30-125         AC Q84AP8.1
#=GS Q5E4F3_VIBF1/23-163         AC Q5E4F3.1
#=GS Q7PC53_SACD2/682-792        AC Q7PC53.1
#=GS I0DQR8_PROSM/23-156         AC I0DQR8.1
#=GS K8WID4_9ENTR/23-156         AC K8WID4.1
#=GS Q7MGC4_VIBVY/44-181         AC Q7MGC4.1
#=GS F2JIU1_CELLD/445-532        AC F2JIU1.1
#=GS Q8B9D6_NPVR1/16-147         AC Q8B9D6.1
A0A0C5WEE2_9GAMM/21-153                .......................................AAAPGAPTID.WG..E..HTYAL..VELNRDAS.SYEDIVVGiHDTVTVTVSWQSWSGDPADTAKVK......LDGNTVW.......TGSGS......-VKSA.....TFD.VS....KGGVYDMTVELCNADG....CSESGSVKLTIADTDGSHLAPLVPVLQENNKPYTNK-s..............
Q12MA8_SHEDO/27-159                    .......................................AAAPGKPSLA.WG..E..TQFAI..IDVNQSAT.AYNQLVTV.KDAAAVSVSWSLWSGNVGERAQVL......LNGNQVW.......EGASS......ASGTA.....NFN.VN....EGGRYQMQVQLCNSEG....CTASDPKTIIVADTDGSHLLPLNAPLLENNRPYTNH-s..............
A5I5R7_CLOBH/41-169                    nkiqlksnsnsyvlnnskvldaqtsapsdfqlskdnwdg----------.--..-..-----..--------.--------.--SPNYTISMDMWYGTNGDAWKLY......ENGKLVHevk.lvnNSPNA......QHAEI.....KLT.NK....SNGTYTYTAELINAAG....VTKSKNTIV----------------------------hevtkndapidvplp
K4KFR0_SIMAS/82-183                    ..........................aapaiawlgdqss----------.--..-..-----..--------.--------.---TSFPLSWNLWWGENGTVWKVK......DNGAVIHtqs.iaaNSPNA......QSASA.....TIK.VT....GTGSRSLVVELCNSDGanevCTPSSAVTVNVS-------------------------ggvtdpgc.......
D4ZGM8_SHEVD/23-155                    ......................................a-SVPGKPTIG.WG..E..TNFSI..IEIDQAAT.AYNQLVTV.KDAAQVSVNWNLWSGELGDSAKVL......FDGVEVW.......SGPST......ASGAA.....TFS.VS....HGGRYQMLVELCNAEG....CTRSAAKEIIVADTDGSHLLPLETQLGENNKPYANK-s..............
B1KH85_SHEWM/23-155                    ......................................a-SVPGKPTIG.WG..E..TNFSI..IEVNQAAT.AYNQLVTV.KDAAEVSVNWNLWSGELGDTAKVL......FDGVEVW.......SGSST......ASGSA.....TFN.IS....QGGRYQMQIELCNAQG....CTLSDAKEIIVADTDGSHLLPLDTQLGENNRPYVNK-s..............
A0A0A2U6P0_9BACL/1558-1644             ..................................adgty----------.--..-..-----..--------.--------.------TITMNMWWGNNGTQYKLY......ENGELIDtqk.ltaSSPSS......QKAST.....NIS.GR....VNGTYVYTCELINSKG....TTECAPHTVTVRDA-----------------------apakpv.........
F7YT96_VIBA7/30-167                    .......................................MAAPATPSVDvYG..S..NNLQFskVELAMESTaGYNQMVKY.YDQAPIAVKFNQWSGTTGNTYKIY......FDGAQVA.......TGPIT.....gSQTTA.....NFS.YA....QGGVYQMAIEACDATG....CSKSAPVEITIADTDGSHLKPLVMNIDPNNKTYTTD-k..............
U4KA43_9VIBR/20-157                    ......................................l-AAPAAPTIDlDG..S..NNLKFskIQLEMQTLkGYHQMVSY.KDLADITIKFNQWSGTTGDTYKIY......FDGVEVA.......TGPIT.....gSTTTA.....AFQ.YG....KGGLYSVEVAACDATG....CSKSAPQELVVADTDGAHLKPLAMNVDPNNKTYNTD-p..............
Q87K43_VIBPA/20-157                    ......................................v-AAPTAPSVDmYG..S..NNLQFskIELAMETTsGYYDMVKY.HDQAKITVKFNQWSGTPGDTYNIY......FDGVKVA.......TGAIT.....gGQTTA.....TFD.YG....QGGLYQMEIEACDATG....CSKSDPAEITIADTDGSHLKPLTMNVDPNNKTYNTD-p..............
A0A0A7EGV5_9GAMM/19-155                ......................................f-AAPSAPSIS.WE..D..QKYSF..VDVNIDGQgSYKSLVTR.KDVVDIAIKWNSWSGDGGDGYKVK......FDGVVVN.......EGSLPa...gtKSGTI.....TFP.YT....KSGRHQMTVELCEGTT....CAASAPKAIVIADTDGGHLDPLPMNVDPNNGNYGT--sp.............
F0LZ75_VIBFN/20-157                    ......................................l-AAPAAPSIDvYG..S..NNLQFskIELAMETTaGYNQMVTY.HDEAPISITFNQWSGETGNTYKIY......FDGEEVA.......SGPIS.....gSQTTA.....SFT.YS....KGGLYQLEVAACDDSG....CSTSAPVELTIADTDGAHLKPLTMNVDPNNKTYTTD-a..............
H2IRU5_RAHAC/23-155                    .......................................AALPGKPTLG.AD..E..TTFSI..IDINQSAS.AYNQLVTV.KNAADVTVTWNLWTGDAGQTAKVL......LNGAQVW.......SGPSG......ATGSA.....TFA.VN....KGGRYQLQVALCNSEG....CTTSDAKQIVVADTDGSHLLPLTSTLKENNQPYNNK-s..............
A0A097B053_9VIBR/20-157                .......................................MAAPTAPSIDvYG..S..NNLQFskIELAMETTsGYNDMVKY.FDEADITIKFNQWSGTTGDTYKVY......FDGAQVA.......TGAIT.....gSQTTA.....SFK.YA....NGGRYQMTIEACDASG....CSTSAPVEIVVADTDGAHLAPLAMNVDPNNKSYNTD-p..............
K7RS87_PROA4/1209-1289                 .................................sgtgsy----------.--..-..-----..--------.--------.------TVTANMWWGTNATSYTFY......ENGKVIG.......SGDLT.....aTTPNAqvarvAVT.GR....DAGTYTYTVTFSNAQG....STTSSPLKVVVA-------------------------g..............
K4KHW4_SIMAS/20-121                    ......................faapgtpniawleatqq----------.--..-..-----..--------.--------.-SGSAIKVDWNMWWGENGTTWTLY......NNGNVQC.......QGSLTpngqnqQSGS-.....CTS.AY....PAGQNKLQVALCNTSG....CTDGNTVTINVV-------------------------nggtvnq........
C9ZB10_STRSW/452-533                   ..............................nwdkdgtft----------.--..-..-----..--------.--------.-------ATANLWWGTNATSYTFY......LDGAVVG.......EGQLA.....aDSPNA....qSPQ.VAlsgvPKGKHSLKVVLTNARG....STESDPVDVTVA-------------------------...............
F2LL47_BURGS/39-185                    ......................................f-AAPGAPALKaWEitSkpHGFVQ..IELDKAGAvPYKDLVRI.NKAVDVPLPFDIYYNGTAVKALAV......VDGVADEasa.ismTGTGG.....tQKGSV.....VAH.VT....RPGKKQMQVRVFDDKG...aFTDSAPLEVMVFDTTPELADDLPDNADKANRPFRN--ts.............
A0A0A2UDL7_9BACL/753-839               .................................lsegsy----------.--..-..-----..--------.--------.------TISMNLWWGNNGTSYKLY......ENGVLIDtq..kltD-ASPm....aQSAQT.....TIS.GK....ANGTYTYVAELTNSKG....TTSSEVLTVKIAN------------------------avpgka.........
B7VTG0_VIBTL/20-157                    ......................................l-AAPTAPSIDmYG..S..NNLQFskIELAMETTsGYNQMVKY.HDKAKVDVKFNQWSGTSGNTYNIY......FDGVKVA.......TGPIT.....gSQTTA.....SFE.YG....QGGLFEMKIEACDETG....CAKSAPAQITIADTDGSHLAPLTMNVDPNNKSYNTD-p..............
A0A089ML38_9BACL/1018-1097             .................................dgdgty----------.--..-..-----..--------.--------.------KVSMNLWWGTNATEYRLY......ENGELIDsqp.lnaHTPSA......QSAAT.....TIS.GR....SAGVYEYRAELVNAAG....VTASDTIKVTV--------------------------i..............
C6D3X7_PAESJ/1814-1912                 ...................................dgsy----------.--..-..-----..--------.--------.------KITMNMWYGYNGTTYKLY......ENGVLVDtkq.ltdNSPTA......QTAST.....AIS.GK....ANGTYTYTCELINSFG....TTSCSPLTVTVKDASPGKP------------------vlsndnwdnngdyk.
A8AIM7_CITK8/22-155                    .......................................AAAPGTPSIT.SG..N..DKFAI..VEVDQAAQ.DYNNLVKVhNDGVDVKVEWNVWSGDAPTSAKVL......LDGKTVW.......SGAGS......AAGSA.....TFK.VK....KGGRYQEQVELCNTSG....CTKSASKLIIVADTDGSHLLPLNTTMKENNKTFAQH-t..............
O91465_GVCPM/18-153                    ......................................h-SKPGTPQIR.WA..T..HKYSL..VEVNEQAQ.SYNSLVKTvHESVPVSLEWDVWSGARGDSVHLV......WDGQVVK.......EGSSD.....eLREQK....iVYN.VR....KGGRSSVAVRLCDGEG....CSDSVPVEVVVADTDGSHLGRLEYEWRENNVPYQRA-p..............
E1SNM7_FERBD/23-154                    .......................................AAIPAKPSIA.-G..D..THFAV..IEVDHGAT.SYNQLINV.KPAAEVSVSWSLWHGELGDTAKVL......LDDQVVW.......QGPSA......ASGTA.....EFE.VS....KAGRYQLTVALCNAEG....CTSSDPMSIQVADTDGSHLAPLDLQLKENNRPYTNT-s..............
F9T7Y1_9VIBR/20-157                    ......................................i-AAPTAPSVDvYG..S..NNLQFskIQLAMETTsGYNQMVKY.FDEADITVKFNQWSGTTGDTYKVY......FDGVQVA.......TGPIA.....gSQTTA.....SFK.YG....KGGLYQMTIEACDATG....CSVSAPVEVTVADTDGSHLKPLAMNIDPNNKSYNTD-p..............
C9ZB10_STRSW/360-447                   ..................................lhdgn----------.--..-..-----..--------.--------.-----YSVKMNLWHGTPGSFFRLY......ENDKLVAarvpttvS--GT.....sQSVVT.....EFK.DR....PNGTYAYRAELINSKG....TTSTNTTTVTVTDA-----------------------apgkpv.........
A5I5R8_CLOBH/654-738                   .................................wwpqdg----------.--..-..-----..--------.--------.----DYTVTMNMWWGVNADKVKIY......ENGVLIS.......EADLTantpqaQTHSV.....KIN.GR....KNGKYTYYAELINGAG....ITRSDDLIVNVT-------------------------esn............
A8G807_SERP5/23-156                    .......................................AAVPGKPTLA.WG..N..TKFAI..VEVDQAAT.AYNNLVKV.KNAADVSVSWNLWNGDTGTTAKVL......LNGKEVW.......SGAST.....gASGTA.....NFK.VN....KGGRYQMQVALCNADG....CTASDATEIVVADTDGSHLAPLKEPLLEKNKPYKQD-s..............
Q9KND8_VIBCH/20-157                    .......................................MAAPSAPSVDvYG..S..NNLQFskIELAMETTaGYNQMVKY.HEEAPITLKFNQWSGVTGNTYKIY......FDGVEVA.......TGPIS.....gSQTTA.....QFT.YP....KGGVYQLVIEACDATG....CTKSAPSEITIADTDGSHLKPLKMNVDPNNKSYT---ipq............
A0KGX3_AERHH/23-156                    .......................................AAAPGKPTIG.WG..E..TKFAI..VEVDQAAT.SYNKLVKVhADGAPVSVSWNLWSGDVGQTAKVL......LDGKEVW.......SGAAS......ASGTA.....NFK.VT....KGGRYQMQVALCNADG....CTLSDKKEILVADTDGSHLLPLKAPLKENNKPYVNK-t..............
G6D3W1_DANPL/75-206                    ....................................cgp---PGKPNLG.WG..E..RTFAI..VEVNQAAT.AYNQLVKR.NDAAQVPVTWNVWSGDPAETARVL......FDGEEVW.......SGSGR......-STSA.....TFP.ID....KGGRYQMKIELCNSDG....CSYSEPTEIVIADTDGSHLPPLEYSMGEKNKPFKQT-s..............
H9JGR2_BOMMO/16-147                    ....................................cgp---PGKPNLG.WG..E..RTFAI..VEVNQAAT.AYNQLVTK.KDAADVSVNWNVWTGDAADKSRVL......LDKKEVW.......SGAGS......-ATSA.....AFK.VK....KGGRYQMQVELCNSDG....CSSSEGVEIVVADTDGSHLRPLDYSIGEKNKPFKQT-s..............
Q84AP8_SACD2/30-125                    ...............................lpathesg----------.--..-..-----..--------.--------.---EAINVHWDMWWGENGTEWQLT......DNGDLRC.......SGSLTan..gqNQQSA.....ECAaNY....SSGSHALQVSLCNTSG....CSESNVVTINVNQGA----------------------ssnvppqvs......
Q5E4F3_VIBF1/23-163                    .......................................AAAPGQAIIS.WM..E..TDFSI..IEIDQAAT.SYKSLVTV.KDFAEVPVTWDRWSGESAEKWRVL......LNGVVVHee...svSPAAS......QKAST.....TLQ.VR....QGGQYEMTVQLCNGSGateeCSTSAAKSIVVADTDGSHLDPLPMNVDPANGNYTTP-a..............
Q7PC53_SACD2/682-792                   ......................veqptaptiawmntsyt----------.--..-..-----..--------.--------.GSSVTVTITWNMYWGTNGNQWQLW......LDGEQVYsan.lttNGQNA......QTDSK.....IIT.IT....GAGAHSVEVKLCNQQDi.nvSCASDSETITL--------------------------qggsdgatssss...
I0DQR8_PROSM/23-156                    .......................................AALPGKPTIQ.WM..D..NTYSI..VEINPNED.KYELLVTR.KEAATFNVSWDLWYGDYGTTAKVY......LNDQEVW.......SGPST.....sSSGQA.....SLS.IS....KGGKYKLKVALCNGDE....CNFSDVVEITVQDTDGSHFAPLQTQLLENNQAYKQD-s..............
K8WID4_9ENTR/23-156                    ......................................s-ATPGTPTIS.WG..N..SQYSI..IEVNHNAT.AYNKLVKV.KDYADVDVSWSLWNGDYGTTAKVL......LNDQEVW.......KGPSK.....gASGSA.....KFK.VY....QGGRYQMQVALCNSDG....CSMSAKKEIIVADTDGSHLLPLKTSLLENNKPYEQN-s..............
Q7MGC4_VIBVY/44-181                    ......................................l-AAPTAPSIDlYG..S..NNLQFskIELAMETTaGYNQMVKY.HDQATISVKFNQWSGNTGDTYNIY......FDGVKVA.......SGPIS.....gSQTAA.....TFQ.YG....KGGLYQMEIEACDATG....CAKSAPAEITIADTDGSHLKPLTMNVDPNNKSYNTD-p..............
F2JIU1_CELLD/445-532                   .............................vahncwngeq----------.--..-..-----..--------.--------.----NYSITFNMWYGVNGTSWRLYendkliFEESLVA.......NGTSA......QQGNA.....NMK.NK....VAGTYTYYAELVNENG....VTKSKPITVTV--------------------------npi............
Q8B9D6_NPVR1/16-147                    ......................................y-AIPGTPVID.WA..D..RNYAL..VEINYEAT.AYENLIKP.KKHVDVQVSWNVWNGDIGDIAYVL......FDEQQVW.......KGDAE......-SKRA.....TIK.VL....VSGQFNMRVKLCNEDG....CSVSNPVLVKIADTDGGHLTPLEYTWLENNKPGRR--ed.............
#=GC seq_cons                          ........................................uhPstPslt..t..p..pphth..l-ls.tsp.sYpphVph.tptssloVsaNhWpGssGsoh+lh......hsGt.Vt.......oGsss......pssoA.....shp.sp....puGpYphplcLCNusG....CopSsshplsVADTDGuHL.PL...h..pNtsatp..s..............
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