GenomeNet

Database: Pfam
Entry: Cluap1
LinkDB: Cluap1
Original site: Cluap1 
#=GF ID   Cluap1
#=GF AC   PF10234.6
#=GF DE   Clusterin-associated protein-1
#=GF AU   KOGs, Finn RD, Coggill PC
#=GF SE   KOGs (KOG3647)
#=GF GA   24.20 24.20;
#=GF TC   27.10 33.60;
#=GF NC   24.00 23.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   15480429
#=GF RT   Isolation and characterization of a novel gene CLUAP1 whose
#=GF RT   expression is frequently upregulated in colon cancer. 
#=GF RA   Takahashi M, Lin YM, Nakamura Y, Furukawa Y; 
#=GF RL   Oncogene. 2004;23:9289-9294.
#=GF DR   INTERPRO; IPR019366;
#=GF CC   This protein is conserved from worms to humans. The protein of
#=GF CC   413 amino acids contains a central coiled-coil domain, possibly
#=GF CC   the region that binds to clusterin. Cluap1 expression is highest
#=GF CC   in the nucleus and gradually increases during late S to G2/M
#=GF CC   phases of the cell cycle and returns to the basal level in the
#=GF CC   G0/G1 phases. In addition, it is upregulated in colon cancer
#=GF CC   tissues compared to corresponding non-cancerous mucosa. It thus
#=GF CC   plays a crucial role in the life of the cell [1].
#=GF SQ   216
#=GS X6LS59_RETFI/283-369      AC X6LS59.1
#=GS B4L8U7_DROMO/14-271       AC B4L8U7.1
#=GS C5LI99_PERM5/1-55         AC C5LI99.1
#=GS B9PY74_TOXGO/15-324       AC B9PY74.1
#=GS F0YCH5_AURAN/14-289       AC F0YCH5.1
#=GS H3BLK7_MOUSE/119-282      AC H3BLK7.1
#=GS B0XI21_CULQU/14-257       AC B0XI21.1
#=GS G0N282_CAEBE/3-293        AC G0N282.1
#=GS G4VQC4_SCHMA/31-301       AC G4VQC4.1
#=GS A0A067BS83_SAPPC/14-281   AC A0A067BS83.1
#=GS M7BSK7_CHEMY/3-167        AC M7BSK7.1
#=GS U3IIA7_ANAPL/14-283       AC U3IIA7.1
#=GS A0A0G2K129_RAT/14-283     AC A0A0G2K129.1
#=GS G3P1N2_GASAC/14-283       AC G3P1N2.1
#=GS E1GB83_LOALO/1-255        AC E1GB83.2
#=GS H3D7N4_TETNG/14-283       AC H3D7N4.1
#=GS E9ITG3_SOLIN/221-316      AC E9ITG3.1
#=GS H3FW98_PRIPA/181-275      AC H3FW98.1
#=GS W5M6H8_LEPOC/15-284       AC W5M6H8.1
#=GS A2DAL0_TRIVA/14-275       AC A2DAL0.1
#=GS A8XZA7_CAEBR/78-228       AC A8XZA7.2
#=GS W4XLG9_STRPU/14-283       AC W4XLG9.1
#=GS E9ITG3_SOLIN/2-198        AC E9ITG3.1
#=GS A0A024MEJ8_BRUMA/42-129   AC A0A024MEJ8.1
#=GS G3I031_CRIGR/1-42         AC G3I031.1
#=GS A0A087ZYK6_APIME/14-282   AC A0A087ZYK6.1
#=GS F7HDE7_CALJA/1-42         AC F7HDE7.1
#=GS A4I1I7_LEIIN/14-279       AC A4I1I7.1
#=GS H0UWD2_CAVPO/14-283       AC H0UWD2.1
#=GS K4DXM7_TRYCR/14-279       AC K4DXM7.1
#=GS H2LQL0_ORYLA/14-282       AC H2LQL0.1
#=GS D2V2H0_NAEGR/3-247        AC D2V2H0.1
#=GS H3CXI0_TETNG/14-282       AC H3CXI0.1
#=GS I3L121_HUMAN/1-117        AC I3L121.1
#=GS M4A2Z3_XIPMA/14-283       AC M4A2Z3.1
#=GS K1Q635_CRAGI/14-284       AC K1Q635.1
#=GS H2YD01_CIOSA/3-273        AC H2YD01.1
#=GS G3RKB1_GORGO/44-254       AC G3RKB1.1
#=GS G6CRN3_DANPL/2-269        AC G6CRN3.1
#=GS B4ILE4_DROSE/14-288       AC B4ILE4.1
#=GS F1RA40_DANRE/14-283       AC F1RA40.1
#=GS A9SKY8_PHYPA/2-71         AC A9SKY8.1
#=GS C5KSL6_PERM5/14-113       AC C5KSL6.1
#=GS E1BT83_CHICK/14-283       AC E1BT83.2
#=GS V4CNE9_LOTGI/14-283       AC V4CNE9.1
#=GS V6U278_GIAIN/14-278       AC V6U278.1
#=GS D2A571_TRICA/14-285       AC D2A571.1
#=GS B4M1P1_DROVI/14-290       AC B4M1P1.1
#=GS A0BPJ7_PARTE/14-287       AC A0BPJ7.1
#=GS U3JP63_FICAL/14-283       AC U3JP63.1
#=GS G3WRK7_SARHA/14-283       AC G3WRK7.1
#=GS A0D714_PARTE/14-286       AC A0D714.1
#=GS E2AT63_CAMFO/3-271        AC E2AT63.1
#=GS A0A067QVA1_ZOONE/14-281   AC A0A067QVA1.1
#=GS CLUA1_HUMAN/14-283        AC Q96AJ1.4
#=GS D8RNG9_SELML/6-274        AC D8RNG9.1
#=GS CLUA1_DANRE/14-283        AC Q7ZVC2.2
#=GS K0TFE1_THAOC/4-195        AC K0TFE1.1
#=GS H2TL69_TAKRU/14-283       AC H2TL69.1
#=GS D8RLZ5_SELML/6-274        AC D8RLZ5.1
#=GS A0A096NLC4_PAPAN/14-283   AC A0A096NLC4.1
#=GS A7SE98_NEMVE/14-282       AC A7SE98.1
#=GS CLUA1_CAEEL/14-304        AC Q6I6D4.2
#=GS H2WEP9_CAEJA/1-59         AC H2WEP9.2
#=GS I3MBH8_SPETR/14-283       AC I3MBH8.1
#=GS B3MRF1_DROAN/14-289       AC B3MRF1.1
#=GS U4UQI8_DENPD/14-285       AC U4UQI8.1
#=GS C1MHX5_MICPC/14-292       AC C1MHX5.1
#=GS L5KHC7_PTEAL/14-283       AC L5KHC7.1
#=GS A0A093BJS0_CHAPE/7-276    AC A0A093BJS0.1
#=GS J9F6H1_WUCBA/1-118        AC J9F6H1.1
#=GS H3C5F4_TETNG/14-283       AC H3C5F4.1
#=GS I1GEH0_AMPQE/14-282       AC I1GEH0.1
#=GS A2DLL3_TRIVA/14-275       AC A2DLL3.1
#=GS F7ASW0_MONDO/14-283       AC F7ASW0.1
#=GS A0A067R4S8_ZOONE/14-84    AC A0A067R4S8.1
#=GS T1G7F4_HELRO/14-291       AC T1G7F4.1
#=GS A0A024MFI6_BRUMA/128-217  AC A0A024MFI6.1
#=GS G5B1H2_HETGA/78-347       AC G5B1H2.1
#=GS A8XZA7_CAEBR/3-82         AC A8XZA7.2
#=GS B4NC22_DROWI/14-290       AC B4NC22.1
#=GS H9JVX8_BOMMO/2-194        AC H9JVX8.1
#=GS T1H9I2_RHOPR/87-373       AC T1H9I2.1
#=GS A0DJV3_PARTE/14-289       AC A0DJV3.1
#=GS Q05AZ5_XENTR/14-283       AC Q05AZ5.1
#=GS L5MA99_MYODS/14-283       AC L5MA99.1
#=GS G1LVW2_AILME/14-283       AC G1LVW2.1
#=GS F6RMJ6_ORNAN/7-273        AC F6RMJ6.2
#=GS F6WNW0_HORSE/14-283       AC F6WNW0.1
#=GS A0A068WZU3_HYMMI/2-262    AC A0A068WZU3.1
#=GS U1MSR8_ASCSU/14-314       AC U1MSR8.1
#=GS H9G581_ANOCA/3-227        AC H9G581.1
#=GS G1T1X1_RABIT/14-286       AC G1T1X1.1
#=GS U6MIW6_EIMMA/80-354       AC U6MIW6.1
#=GS W5JBA3_ANODA/14-284       AC W5JBA3.1
#=GS V8NYL6_OPHHA/33-245       AC V8NYL6.1
#=GS B7PGD6_IXOSC/9-273        AC B7PGD6.1
#=GS V8NYL6_OPHHA/3-38         AC V8NYL6.1
#=GS G3WRK6_SARHA/14-286       AC G3WRK6.1
#=GS Q4DIB8_TRYCC/14-279       AC Q4DIB8.1
#=GS A0A0B2UWT1_TOXCA/14-282   AC A0A0B2UWT1.1
#=GS CLUA1_MOUSE/14-283        AC Q8R3P7.1
#=GS F2URB7_SALR5/14-146       AC F2URB7.1
#=GS F2URB7_SALR5/145-192      AC F2URB7.1
#=GS F6STI1_MACMU/30-299       AC F6STI1.1
#=GS G3T0T0_LOXAF/14-283       AC G3T0T0.1
#=GS Q7QF08_ANOGA/14-284       AC Q7QF08.4
#=GS A0A077ZJX2_TRITR/36-308   AC A0A077ZJX2.1
#=GS A0A068Y292_ECHMU/3-271    AC A0A068Y292.1
#=GS H0Z087_TAEGU/13-282       AC H0Z087.1
#=GS J9P5I7_CANFA/14-283       AC J9P5I7.1
#=GS D0N834_PHYIT/14-294       AC D0N834.1
#=GS H2QAG8_PANTR/14-283       AC H2QAG8.1
#=GS Q16MH9_AEDAE/14-284       AC Q16MH9.1
#=GS I3L455_HUMAN/14-49        AC I3L455.1
#=GS I3L3S9_HUMAN/14-283       AC I3L3S9.1
#=GS C3Z7T3_BRAFL/14-283       AC C3Z7T3.1
#=GS Q228X0_TETTS/14-287       AC Q228X0.1
#=GS J9K349_ACYPI/14-279       AC J9K349.1
#=GS F6STM5_MACMU/14-283       AC F6STM5.1
#=GS B3RPP2_TRIAD/14-282       AC B3RPP2.1
#=GS H3H271_PHYRM/317-597      AC H3H271.1
#=GS B4H2Y5_DROPE/14-287       AC B4H2Y5.1
#=GS F9WCG0_TRYCI/14-278       AC F9WCG0.1
#=GS A0A024MFI6_BRUMA/6-133    AC A0A024MFI6.1
#=GS I3L1J4_HUMAN/73-201       AC I3L1J4.1
#=GS C1EA98_MICSR/14-94        AC C1EA98.1
#=GS T1FVV9_HELRO/146-332      AC T1FVV9.1
#=GS B8C1X8_THAPS/1-170        AC B8C1X8.1
#=GS H3AG34_LATCH/1-211        AC H3AG34.1
#=GS Q4CP52_TRYCC/14-279       AC Q4CP52.1
#=GS B4JNU9_DROGR/14-291       AC B4JNU9.1
#=GS G7Q0C9_MACFA/14-283       AC G7Q0C9.1
#=GS M3YUI1_MUSPF/14-283       AC M3YUI1.1
#=GS E4XZK8_OIKDI/1-246        AC E4XZK8.1
#=GS W4Y5Z7_STRPU/271-391      AC W4Y5Z7.1
#=GS F1RK42_PIG/1-109          AC F1RK42.1
#=GS A4HEE7_LEIBR/14-279       AC A4HEE7.1
#=GS F4WGT1_ACREC/2-270        AC F4WGT1.1
#=GS A7SUP1_NEMVE/1-210        AC A7SUP1.1
#=GS A8BGV3_GIAIC/14-278       AC A8BGV3.1
#=GS I3K414_ORENI/14-283       AC I3K414.1
#=GS I3LL21_PIG/1-109          AC I3LL21.1
#=GS W5M6G4_LEPOC/14-283       AC W5M6G4.1
#=GS D8RLZ6_SELML/11-160       AC D8RLZ6.1
#=GS H3FW98_PRIPA/10-175       AC H3FW98.1
#=GS G1Q0T4_MYOLU/1-85         AC G1Q0T4.1
#=GS K7ETZ5_PONAB/14-236       AC K7ETZ5.1
#=GS E5S4W1_TRISP/2-300        AC E5S4W1.1
#=GS G3RKB1_GORGO/14-46        AC G3RKB1.1
#=GS U6GQG0_EIMAC/81-355       AC U6GQG0.1
#=GS F6RR79_MACMU/14-283       AC F6RR79.1
#=GS J9ED44_WUCBA/6-80         AC J9ED44.1
#=GS Q4Q9V0_LEIMA/14-279       AC Q4Q9V0.1
#=GS A0CPU5_PARTE/14-288       AC A0CPU5.1
#=GS M3WGM6_FELCA/14-283       AC M3WGM6.1
#=GS A8QFY5_BRUMA/139-229      AC A8QFY5.2
#=GS F0V797_NEOCL/2-164        AC F0V797.1
#=GS I3L487_HUMAN/3-121        AC I3L487.5
#=GS Q9VR64_DROME/14-288       AC Q9VR64.1
#=GS Q16GM2_AEDAE/14-284       AC Q16GM2.1
#=GS B4LA63_DROMO/14-271       AC B4LA63.1
#=GS A9V562_MONBE/453-723      AC A9V562.1
#=GS A0A0D9RC92_CHLSB/14-283   AC A0A0D9RC92.1
#=GS H0XE88_OTOGA/1-210        AC H0XE88.1
#=GS W4X161_ATTCE/3-63         AC W4X161.1
#=GS A0A091D3L3_FUKDA/14-283   AC A0A091D3L3.1
#=GS CLUA1_RAT/3-272           AC Q6AYJ5.1
#=GS W5NUY0_SHEEP/14-283       AC W5NUY0.1
#=GS F6YBF5_XENTR/14-283       AC F6YBF5.1
#=GS Q57WZ2_TRYB2/14-278       AC Q57WZ2.1
#=GS E3NEV7_CAERE/14-306       AC E3NEV7.1
#=GS G1REX5_NOMLE/14-283       AC G1REX5.1
#=GS G0R0U0_ICHMG/14-286       AC G0R0U0.1
#=GS E2QYA5_CANFA/14-283       AC E2QYA5.2
#=GS E2BJI1_HARSA/14-283       AC E2BJI1.1
#=GS F4P424_BATDJ/2-267        AC F4P424.1
#=GS X6LS59_RETFI/73-272       AC X6LS59.1
#=GS F6ZII8_CIOIN/14-286       AC F6ZII8.2
#=GS E9FS11_DAPPU/2-266        AC E9FS11.1
#=GS M7BSK7_CHEMY/170-237      AC M7BSK7.1
#=GS J3KNW5_HUMAN/14-283       AC J3KNW5.1
#=GS C5KSL6_PERM5/109-248      AC C5KSL6.1
#=GS B4R445_DROSI/6-182        AC B4R445.1
#=GS W5KID1_ASTMX/14-284       AC W5KID1.1
#=GS A0A096M439_POEFO/14-283   AC A0A096M439.1
#=GS E9Q8M4_MOUSE/3-206        AC E9Q8M4.1
#=GS G7Y5H0_CLOSI/14-283       AC G7Y5H0.1
#=GS E2C4G9_HARSA/3-272        AC E2C4G9.1
#=GS D8LND8_ECTSI/2-105        AC D8LND8.1
#=GS R1CV11_EMIHU/14-219       AC R1CV11.1
#=GS C1EA98_MICSR/130-323      AC C1EA98.1
#=GS I3L1J4_HUMAN/14-75        AC I3L1J4.1
#=GS G4YTW6_PHYSP/14-294       AC G4YTW6.1
#=GS A8QFY5_BRUMA/14-142       AC A8QFY5.2
#=GS G1PXJ3_MYOLU/14-283       AC G1PXJ3.1
#=GS T1JPQ2_TETUR/18-287       AC T1JPQ2.1
#=GS D8LND8_ECTSI/122-247      AC D8LND8.1
#=GS F7GSJ4_CALJA/14-283       AC F7GSJ4.1
#=GS A7YWT7_BOVIN/14-283       AC A7YWT7.1
#=GS E1ZBQ4_CHLVA/26-278       AC E1ZBQ4.1
#=GS G1NB32_MELGA/14-283       AC G1NB32.2
#=GS K3WZQ5_PYTUL/14-268       AC K3WZQ5.1
#=GS G3I032_CRIGR/14-238       AC G3I032.1
#=GS T1IRF1_STRMM/14-282       AC T1IRF1.1
#=GS D8U506_VOLCA/14-279       AC D8U506.1
#=GS A0A088A5L6_APIME/1-247    AC A0A088A5L6.1
#=GS E0VSQ8_PEDHC/14-282       AC E0VSQ8.1
#=GS A8J6F1_CHLRE/14-279       AC A8J6F1.1
#=GS T1GH81_MEGSC/35-298       AC T1GH81.1
#=GS A0A044V9T1_ONCVO/6-273    AC A0A044V9T1.1
#=GS T1FVV9_HELRO/14-124       AC T1FVV9.1
#=GS Q29JG2_DROPS/14-287       AC Q29JG2.2
#=GS A0A096M4D8_POEFO/14-283   AC A0A096M4D8.1
#=GS D3Z1F2_MOUSE/3-188        AC D3Z1F2.6
#=GS L9LED6_TUPCH/11-280       AC L9LED6.1
X6LS59_RETFI/283-369                 ...............nggiqty------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.------------------QNQKDGKNLMRKITRKENELERLQKRLQSVK............NIK..PAFMAEFEE....TQIKNVALYKEWVNKHINLCYLQNELEKYNDKEKQ-kh.........................................
B4L8U7_DROMO/14-271                  ......................KLLGFS.RVLPLQALAT.Hhg.sltNFYIVAEVIQWVSGLLEPGVILA.GNVETEEQRVLLIRVATEFFV..............TKAAIKLNPRKLYAAAAVSCTELQKITSLLIAPTRIEed....veNRDEESEQD.CSLK..........................................................QADIGDK.M...DE.LRRA...RDLS.SDLTQRGAGLFDLLSKELI.................................NKSGRVAQVQ..................RAMEL....VSVERTLK.NAIQASDLKLQSTSAQASRAGENQA----------------ETR--GTP............KLR..PAHMSEFEE....CERELQQLFQRYFLRFHLRDALRNYLKARIK-----rrgt.......................................
C5LI99_PERM5/1-55                    ...................hhh------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.---------------------------------------------QGLR............TVR..PAFMDEYEE....LQEFMDQLYEAYVDRFRNLDYLEHELDILNREEEE-r..........................................
B9PY74_TOXGO/15-324                  ....................ma--LGFTgSPLSFGLFSSgP......RFLSVADVLRWLALQCTGVKELPkRPLENADDRVAFVEQISELLA..............RHASFCLDVETIYAAEGAAVKELIRLARTLLNAVQSAinrpalpaTLEKQLQTI.STSTavelmpvsrgdcv...............................ghsagrpdgaccidQLAMAAK.L...QQ.LNLS...RSAA.SQLVDTAASLLQAFERHSRper...........................vilRRRVRDFLLRlglh..........ldsgADQEL....EHIQLQLA.EQLRRAKADLLDTQHACLDLENELT----------QDSDRAQKRLQSLQ............NLK..PAFLEDHKK....LMAELQETYDMYVACVRNERFLEMEAEKRQAK----arag.......................................
F0YCH5_AURAN/14-289                  ......................RALGYQ.RLVSVENFRK.P......NFELVASALYWMVKRYDPEINVS.DCIEKEDDRVDFLTVTAQALA..............SKAKIKLNTKRLYAADGRAVKELLKVATMLYNASKAN........--EEAAKED.PLRE..........................................................VQPLNSR.I...KD.IKLA...RTLA.TEITDKGARLYDLLGKEKD.................................VKQDRQSALNfldti........ssnldSTVEH....GHIQKSIT.TLVSNVSEDIEQMKKQCDELTADERTLDSKIKKKQSELERHEKRLKSLQ............TVR..PAFMDEYEK....LERELQKQYGVYLERFRNLDYLQNELEMYNKSEKE-k..........................................
H3BLK7_MOUSE/119-282                 ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDIETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSNVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLE-....--------.-------------------------------------------------............---..---------....------------------------------------...........................................
B0XI21_CULQU/14-257                  ......................KLLGYP.NNIPLSVLNT.Pfg.gpeSFKAYSDILSWLVGRLEPTLTLA.GGTCTEQDRILFVRSATEFLV..............TKSSIKVNPRKLYASSTAAAKELLKVTSLLIASPKVT........--GLDEESI.KSHV..........................................................EIDLSDK.M...ED.LKKV...RGLS.SELTNRGAALYDLLKKELV.................................NRETRTVQST..................RSLEL....ASVEKVIK.TAIGSLETKLGAAKGGEWELELEDS-------AQVVELERSKQRLQALQ............KVR..PAYLEEFEK....LELELKNLYEQFRT----------------------rn.........................................
G0N282_CAEBE/3-293                   ......................RSLRYP.RLMSIENFRT.P......NFQLVAELLEWIVKKFEPDATLDaQMILTEADRVNFIKNAVLLML..............QNSRIKMNPKKLYMADGYAVQELLPALRILYLAKSED........-PNMDNTPK.WSQV..........................................................KNKLSAK.M...QE.VRIT...RQLS.SQLPETGALLSELLSKPEY.................................LTNQHEKAAN..................RQVQL....AETEKLLQ.GTVQGIALEAEQISTKLNNVASDEAELDEKIERKKREYEQLQKRFAKLQ............SFR..PQYMDEYER....FEERLKKLYEVYVLNFRNLTYLRKVHDDLARSERQ-rqeelekamrlavekmrleqekkd...................
G4VQC4_SCHMA/31-301                  ......................RSLGYP.RVISLENFRT.P......NFPLVAEILRWLVCRYDSYAELP.SRLDSEQDRVLFIKTAIRLIF..............TKACIKLNSKRLYQADGFAVRELIKITRILYEATQNS........DSESKDEQNcLNVT..........................................................EIFDFRK.V...KQ.LQEA...RNLC.SQLASSGASLNSLLNKEVD.................................IKELRGTSLR..................RQIDR....EYVEESIK.TAKNAINGQIDKIQSSLVNITADETNLDMKIEKKRSELERNRKRLSTLQ............SVR..PVYMEEYEQ....LEEELSSLYTTYLTKFRNLTFLESQYEY--------lldninqnne.................................
A0A067BS83_SAPPC/14-281              ......................RALGYP.RPVSVENFRT.P......NFELVSDLLYWMAKKYDPSSSVT.EEIDTEEDRIAFLTSVTSEFF..............NKARIRLNPKKLYAADGFAVKELLKVAKVLYEASRID........PSSLETDDD.DLST..........................................................KSLLGSK.L...KD.AKAT...RALS.AEITDCGAKLFDLLENELD.................................VREARSNALR..................FLDTH....KFLEKSIK.ELIAGVSENVESMERQCAELDAEEKALSAKIKKAQGDLERSEKRLKSLQ............NVR..PAFMDEYEK....LEKELERQYAIYCERFRNLDYLQRELDLHNDREL--kk.........................................
M7BSK7_CHEMY/3-167                   ......................RALGYP.RLISMENFRT.P......NFMLVSEMLLWLCKRYEPQTDVP.SDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mETTSVSEEE.STKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSRGASLYDLLGKEVE.................................LREM------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------dlllaasgaqh................................
U3IIA7_ANAPL/14-283                  ......................RALGYP.RLISLENFHA.P......NFMLVAEVLLWLGERYEPQTDIP.PDIETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYGAMNTKg......vERTDVSEED.SSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LREARTESIA..................RPLEI....NEAEKMVK.IAIDCVLEQVQKTKDMLSNVALDEANLEAKIEKRKLELERSQKRLQTLQ............SVR..PAFMDEYEK....IEEQLQKQYSSYLEKFHNLTYLEQLLDDHHRTEQE-m..........................................
A0A0G2K129_RAT/14-283                ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDTETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSNVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....VEEELQKQYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
G3P1N2_GASAC/14-283                  ......................RALGYP.RLISMENFRT.P......NFTLVAEILIWLVRRYEPQMDIP.TDVDTESDRIFFIKAVAQFMV..............TKAHIKLNTKRLYQADGYAVKEMLKITSVLYSAMKTKq......mALADAAEED.NSKF..........................................................KFDLGSR.I...SD.LKAA...RQLA.SEVTSKGASLYDLLGKEVD.................................LREKRTASIA..................RPLEI....NGTEKALK.AAIKEVLGSVEKTKDMLSNVVSDETSLDAKIEKKKQEQERNLKRLQTLQ............SVR..PAFMDEYEK....IEEDLQKQYETFVEKFRNLCFLESQLDEYHRMEQE-r..........................................
E1GB83_LOALO/1-255                   ......................------.----------.-......-----------------------.---------------------..............-------------MADGHAVQEIAVVVRNLYEITRHP........NGLDQNATI.NSMRnimlgkislfyncndgkllhhkmnfeeknlenkrknecllslylskngftitrisafvSLLLAAK.AflgEE.LQKC...RQLA.LQIANHGATLYDLLGKEVI.................................ARNERNKALS..................FSFNL....SDGEKAIL.QAVQIIQEELSVINHNLQNVSSDEAALDAKIERRKKEYDQQQKRLAKLQ............SFR..PQCMDEYEK....YEMKLKQLYAIYVLKFRNVAFLQGLQNEFDHAEQQ-r..........................................
H3D7N4_TETNG/14-283                  ......................RALGYP.RLISMQSFRT.P......NFPLVAEILIWLVKRYEPATDIP.TDISTETDRVLFIKAVAEFMA..............NRAHVELNTKNVYKADGYAVKEMLKVTSPLHSAMRTTe......tALGDQIEED.NARS..........................................................KISVAPQ.S...SD.LKAA...RQLA.SSVTSKGASLCDLLGKETD.................................LKDSLSVAVA..................KPFEI....NEIEKALK.AAITEDLERLDKTKDMLAKLVSDEASLDGKTEKKKQELERNQKRLRTVQ............SVR..PAIMDEYEK....IEEELKEQYELYVKKFRTLCYLESQLEALHRLEQE-r..........................................
E9ITG3_SOLIN/221-316                 .......cliviqqhnlsnnky------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.----------------NLILKETEQNLDARIERRKTELDRNQKRLHTLK............KVR..PAFMEEFEK....LEVELRALYDDYLQKFRYLAYLEHLYEDTAKMEQE-r..........................................
H3FW98_PRIPA/181-275                 .............lqqfvmfhk------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-----------LVKEKIANIDSDERSLDEKIERKRREFDHMQKRYAKLQ............SYR..PAHMDEYER....YEEKLKAAYELYVIKFRNLTYLRQLQSELERADQQ-r..........................................
W5M6H8_LEPOC/15-284                  ......................RALGYT.RLISMENFRT.P......NFTLVAEILIWLVKRYEPHMDIP.TDVDTETDRVFFIKAVAQFMA..............SKAHVKLNTKRLYQADGYAVKEMLKITSVLYSAMKTKg......mASGDQPEED.SSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKETE.................................LREMRTAAIA..................RPLEI....NETEKTLQ.AAVREVLHQVQKTKDMLNNVASDEVSLEAKIEKKKQELERNQKRLQTLQ............SVR..PAFMDEYEK....IEEDLQKQYEVYVEKFRNLSFLEQQLEDYHRLEQE-r..........................................
A2DAL0_TRIVA/14-275                  ......................RILGYP.NPVGIDSFDT.P......NFGLMANLLHWLATLYDPEIVVL.VELSNEYGRVEFVRGIVQQLA..............IKSGIRLNPRKLYASDRYAVRELLKIATPIYRGVKCA........----EDKRG.---T..........................................................VSTSFPK.N...QN.TQKI...SQLS.ATVPRHSVELYDQLDKEVQ.................................IRETRTKILA..................TVPSL....DDFEKQVL.EAVDGTSARLDQLNKELDRFNSDEDALNTKIRQRKHEYDRQSKRLMSVQ............TIR..PAYMDEYEM....LEQELSEQFKTYFQHYRNVDYFEKELLKHTDK----vkksn......................................
A8XZA7_CAEBR/78-228                  .....................q------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.VRIT...RQLS.NQLPETGALLSELLSKQEY.................................LSNQHEKAAA..................RSIPL....AEAEKLLN.ATIQGIAQDAEQLANKLNNVASDEAELDEKIERKKREYEQLQKRFAKLQ............AFR..PQYMDEYER....FEERLQKLYEVYVLNFRNLAYLRKVHDDLARSERQ-rqee.......................................
W4XLG9_STRPU/14-283                  ......................RALGYP.RLISMENFRT.P......NFALVAEVLIWLVKRYDPNADIP.SDTDSEQDRVIFIKSAAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYNAVRTKv......gGQDGDDDDG.ASAM..........................................................SFDISSK.I...QD.LKAS...RQLA.SEITSKGASLYDLLGKEVE.................................LREIRTMAIN..................KPLEI....NEIEKGLR.NSIKAVEQNVKKTQKMLENVASDEANLEAKIEKKRSEMERNEKRLSTLQ............SVR..PAFMDEYEK....LEGDLQKQYEVFIERYRNLTYLEHQLDEYSRAEQD-r..........................................
E9ITG3_SOLIN/2-198                   ......................RVLGYP.RLISIANFRV.P......NFPLVAEILVWLVKRFEPDVDVF.SDHDIEEQRVTLIRSVAEFMA..............LKTNVKLNTKKLYQADGYAVKEMLKIATLLYDAQSSS.......sAEQNQSSGN.QNVV..........................................................DFDISDK.I...NE.LKTT...RHLA.SQLTINGATLFDLLGREVE.................................LREIRNTKIA..................RQFDT....SEIEVALK.EVIENTRKEINETKKQIDNVK----------------------------............---..---------....------------------------------------vnif.......................................
A0A024MEJ8_BRUMA/42-129              .................vkfhl------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.------LEELAVINHNLQNVSSDEAALDAKIERRKKEYDQQQKRLAKLQ............SFR..PQCMDEYEK....YEMKLKQLYAIYVLKFRNVSFLQ-------------glqvw......................................
G3I031_CRIGR/1-42                    ......................------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---MDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
A0A087ZYK6_APIME/14-282              ......................RVLGYP.RLISVGNFRL.P......NFPLVAEILVWLVKRFDPDTDIP.SDHTTEEERISLIRAVAEFMA..............LKTNIKLNTKKLYQADGYAVKELLKVATLLYDAQNNS.......nINNVMSDDN.FNTV..........................................................NFDISNK.I...NE.LKST...RQLA.SQLTVTGASLFDLLGREVD.................................LREIRNSKVA..................RQFDI....SEIETALK.SVIENIRKEIEETKKQIESVKDTEQNLDARIERRRAELDRNQKRLQTLK............KVR..PAFMEEFEK....LEVELRILYDDYIQKFRYLAYLEHLYEDSAKTEQE-r..........................................
F7HDE7_CALJA/1-42                    ......................------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---MDEYEK....VEEELQKQYDIYLEKFQNLTYLEKQLEDYHRMEQE-r..........................................
A4I1I7_LEIIN/14-279                  ......................RLLGYP.QLISMESFRE.P......NVELVADCIHWLITRYEPSAEVT.FNIEREHNRVTFFKQVCEVAL..............AKGRIKLNVKKLYQADGHAVQEMLKLANVLKKAMKAT........--DTEEPDF.TALQ..........................................................QMAAQKN.V...SD.AKAV...QQLC.SELTADGSSLFFLVEGELN.................................SRGDRQRILS..................RATEV....GEFERRLR.ELLTNVTQEVDQYQQSIVNLSADESNLEQKIENKKAHLERAQKQYKSAM............ATN..PAFLKEYEN....HEKKLHAQFVDYLEQYRNLEFLEHQIAKYNAKED--am.........................................
H0UWD2_CAVPO/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSKVGEED.ISKF..........................................................KFDLSSK.I...AD.LKAA...RQLA.SEITSKGAFLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAVKEILSQVQKTKDLLSNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEEHHRMEQE-r..........................................
K4DXM7_TRYCR/14-279                  ......................RLLGYP.NLISMESFRN.P......NVELVADCLFWLIKRYEPSAEIV.YEIEREGDRIFFFKQICEVAL..............AKGQIKLNIKKLYQSDGNAVQEMLILASVLKKAMNAT........--EAEEADY.TSVQ..........................................................QMVAQKN.V...QD.AKRV...QQLC.SDLTSDGSALFFLIEEEIS.................................QRGERQRVLS..................RATEV....GEFERRLR.DVLANVGKQVEQLQTTIMNLSADETTLEQKIESKKTQLERAQKRLKSLM............AVR..PAFMEEYEK....HEGDLQSQFVVYLEQYRNLEYLEHELAKFNAAED--av.........................................
H2LQL0_ORYLA/14-282                  .....................t-ALGYP.RRISTENFRT.P......NFPLVAEILIWLVKRYEPHNEIP.TDVDTEADRIFFIKTVAQFMA..............AKAHIKLNTKRLYQADGYAVKEMLKISSVLHSAMKTK.......eMALEDRAED.DNKF..........................................................RSDIGSR.I...SD.LKAA...RQLA.SEVTTTGASLYDLLGKEVD.................................LRERRTVAIA..................RPLDI....NETEKALR.AATKDVLENVAKTKDMLNNVVSDEASLDAKIERKKQDLERHQKRLQTLQ............SVR..PAFMDEYEK....IEEELKKQYDLYEKKFRNLSFLESQLEEHHRLEKE-r..........................................
D2V2H0_NAEGR/3-247                   ................lmltny------.----------.-......--------------RYDPNVDIV.EGTDTVEERLTFLKSICEVVY..............YKARVKLNIKRLYQADGYAVKELLKLAKLLNDATILAk......sVEESDDYET.ASLQ..........................................................QLNSSKF.Q...LN.VKQI...RSIA.TELTELGAELHELLGKELE.................................LKQERLEAIS..................FPHNI....ETIKEHIE.KKNIEAIDMISELQKSINDLKKDEDSLKDKKKRKETELERAKKRLSRVS............NFR..PAFMDEYEQ....KETDLQELYRKYVEKYRNIEYLEHELEKHRKAEA--ei.........................................
H3CXI0_TETNG/14-282                  ......................RALGYP.RIISMQSFRT.P......NFPLVAEILMWLVKRYEPRTEIP.TDISTEADRVLFIKAVAEFME..............NKAHVELNTKNVYKADGYAVKEMLKVTALLFGAMKTTe......tALGDRSDED.AGKL..........................................................RVN-TSQ.T...SD.LKAA...RQLA.SVITSKGASLCDLLAKEVD.................................LKESRSVAMA..................KPFEM....NEIEKALR.AAIRDDLESLETTRDMLSKLVSDEPTLDGKIQKKKQELERNQKRFRTVQ............SVR..PAIMDEYEK....IEEELKEQYEAYVKKFRILCCLESQLEAYHRLEQE-r..........................................
I3L121_HUMAN/1-117                   .....................m------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----RTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
M4A2Z3_XIPMA/14-283                  ......................RALGYP.RLISMENFTT.P......NFTLVAEILIWLVRRYEPHVDIP.TDVDTESDRIFFIKAVVQFMA..............TKAHIKLNTKHLYQADGYAVKEMLKITSVLYNAMKTKq......mALGDAVEED.SNKF..........................................................KFDLGSR.I...SE.LKAA...RQLA.SEITSRGASLYDLLGKEAE.................................LREMRTAAIA..................RPLEI....NETEKALR.AAIKETLEIVEKIKEMLSNVVSDEASLDAKIEKKKQDLERHQKRLQTLQ............SVR..PAFMDEFEK....IEEELQKQYEIFVEKFRNLSYLESQLDEYHRLEQE-r..........................................
K1Q635_CRAGI/14-284                  ......................RALGYP.RLISMENFRN.P......NFPLVAEVMRWLVKRYDPNADIH.CDIDTDQDRVIFIKTVAEFMH..............TKAHIKMNTKKLYQSDGYAVKEMLKVTSMLYNAMKTNs.....ssQSETDNEDD.SSHL..........................................................SFDISSK.I...ND.LKEA...RRLA.SEITTKGATLYDLLGKEVD.................................LREQRSIVIA..................KSLEI....NEVEGGIT.GSIKGVENEIKKYLMQLDNVASDEANLEAKIEKKKNELERNNKRLQTLQ............SVR..PAYMDEYEK....LEEDLQKLYEVYMEKFRNLTYLEAQQEEYNRAEQD-k..........................................
H2YD01_CIOSA/3-273                   ......................RGLGYP.RLISMENFRQ.P......NFELVAEILLWLIQRYEPDAHIP.QDVDTEQDRVIFIKSSAQFIA..............TKIHLKLNTKRLYMADGYAVKELLKVATVLHSAMKATt......sLAKSDSHDS.PSLS..........................................................SFDIASK.I...NE.LKAV...RQLA.SEVTQRGATLYHLLSKEPE.................................LRNARTDALA..................QPMDI....NTIEKGLRwSSIMKVEQEAKATLHKLDNVAADEANLEAKIEKRKTELERAKKRLSTLQ............NVR..PAFMDEFER....LEEELKGHYENYLIKFRNMTFLEHQMEDYNRQEQ--ir.........................................
G3RKB1_GORGO/44-254                  .....................k------.----------.-......-----------------------.--------------------A..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVQ.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
G6CRN3_DANPL/2-269                   ......................RSLGFP.QLISLESFRS.P......NWPLVESCSRWLAARVEPDALLA.GGADTLEQRVALVTHATELFH..............SRANLKLNGKRIYGADGWAVRELLKVANLLRSALDTP........-RHDDQLAD.TDTL..........................................................VYDVSNR.I...GE.IKQA...RTLA.TEITAQGAFLYDLLAKEPE.................................NKDHRNKALS..................RQMDL....SSLETALS.RAVEAMSSRVDAVREQTASVAASEAALDAKIERRRAELQRAEKRLLTLQ............KIK..PAYQSELTS....LETEIASLWDHYVLRYRCVEALKHRLSVLETAQ---aeaa.......................................
B4ILE4_DROSE/14-288                  ......................KLLGFP.RVFPLQSLAN.Qhg.slaSFHIVAELLQWLAGLMEPGATLP.GGVESEEQRVLLVRSATEFFV..............TKAAIRINPRKLYEAAAVTAAELKKVTRLLTSPGQNE.......aDNDEEDQRD.QYRSl........................................................nPVDIGDK.I...EE.LRKA...RELA.TDLTQRGTTICEMLSKELL.................................HKESLMSQAQ..................RPLEL....LSVERTLK.NAIQASQVRLQSSKAQLEAAKVELNALGSKLQRRRAELERTRQRLEALQ............RIR..PAHMAEFED....CEKELQELFQRYFLRLHVRDALKSQLDLRTKR----atp........................................
F1RA40_DANRE/14-283                  ......................RALGYP.RLISMENFRS.P......NFPLVAEILIWLVKRYEPQMEIP.SDVDTESDRVFFIKAVAQFMA..............TKAHVKLNLKRLYQADGYAVKEMLKITSILYNAMKTKe......nAGGDQNNDE.NSKF..........................................................KFDLGSK.I...AD.LKLA...RQLG.SEITAKGAALFDLLGQEED.................................LRESRTAAIA..................RPLEI....TETERAIR.AAVKDVTESIQMTKDLLNNVSSDEASLEAKIEKKKQDLERNQKRLQTLQ............SVR..PAFMDEYEK....IEEDLEKQYQTYVEKYRNLSFLEQQLDDYHRVEQE-r..........................................
A9SKY8_PHYPA/2-71                    ....................ee--LGYP.SKVSMESFNS.P......NFELVANSLHWLMLRFDPTIDLV.KDISTEASRVNFVKAATKLMV..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------yirndntnv..................................
C5KSL6_PERM5/14-113                  ......................RSLGFH.RVVSISNFKE.P......NFELTAEIMDWLVTRLNPDVNLP.EDIDTDTHRVEFIAQAIEAVG..............TCTNIRMNARKLYGADNYAVKEMLKVKVL--------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------earavgngfn.................................
E1BT83_CHICK/14-283                  ......................RALGYP.RLVSMENFHA.P......NFALVAELLLWLVRRYEPQSDIP.PDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEg......mERTDITEED.SSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGANLYDYLAKRVD.................................LKEARTESIA..................RPLEI....NEAEKMMK.VAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQ............SVR..PAFMDEYEK....IEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQE-m..........................................
V4CNE9_LOTGI/14-283                  ......................RALGYH.RLISMENFRT.P......NFPLVAEVLTWLVKRFEPNADVH.PDIDTEQDRVIFIKTVAEFMA..............TKAHIKLNTKKLYQSDGYAVKELLKVTSVLYSAVKTNv......eKALEDADDD.TSNV..........................................................SFDVSSR.I...ND.LKEA...RMLA.SSITTKGAALYDLLGKEVD.................................LREMRVNVVA..................RPLEI....NEVESGLK.GSIKAVEADIKKTLTMLDNVASDEANLEAKIEKRKNEMERNQKRLMTLQ............SVR..PAYMDEYER....FEEDLQKLYSQYLIKFRNLTYLEQQLEEQQKAEQD-k..........................................
V6U278_GIAIN/14-278                  ....................tq--IGFP.RPISIDTFRK.P......DFFLVAEILHYIITIVAPNNAIA.MDIGTQEDRVYFITTVVGVLQ..............STLHLKLDPKKIYAAGPEAVRELRKIVQEVATYIGAT........-AVSADKGS.YSAA..........................................................SVDLTLH.S...NA.LRVA...---S.SKIVEASTKLLTQLRLHVD................................dLYQRMQQAMS..................SQPDA....LSLSGAVQ.QRIKNLASECSALQEEVTTNKREKAKLEEQMNQKKQSITHTMDRLDAIR............STK..PPFLAELEA....MEAELSKLHLEYARKFRSLLFLEGQLRANDVREQQ-r..........................................
D2A571_TRICA/14-285                  ......................RALGYP.SLISMESFRT.P......NFPLVADLLVWLAKRFDPDVDIP.PEIDTEDDRVKLIRNAAQFMA..............LKANIKLNTKRLYQADGYAVKELLKITSLLYDALNMN........LEEKEDENF.EEEMls......................................................lkDFDLSDK.I...NE.LKLS...RQLA.SEITTTGATLFDLLGKEVE.................................LKAARHKSVS..................RQYEI....NEVEAGIK.KAIEALKTEIDESKQLIDNVSATEANLDNKIERRKVEIDRYEKRLQTLK............KVR..PAFMEEFTA....LEAELEQLFVQYSTRVRILNQLERLVSETERQQL--ek.........................................
B4M1P1_DROVI/14-290                  ......................KLLGFP.RVFPLQALAT.Phg.nlaSFHIVAELLQWLAGLLEPGAVLA.GGVESEEQRVMLIRSATEFFL..............TKSAIRLNPRKLYAAAAVSATELQKITRLLIAPTQAEeg...vdrEEERERDQY.RSLN..........................................................QVDIGDK.M...DE.LRRA...RELS.SDLTQRGAALFDLLSKELV.................................NKEARLAQAQ..................RPMEL....LGVERTMK.NAIQANQLKLQSSRAQLENARVELNALKSKLQRKRAELERTKQRLDALQ............KIR..PAHMAEFEE....CEKELQQLFQRYFLRLHVRDALRTQMEMRTQR----rat........................................
A0BPJ7_PARTE/14-287                  ......................RALGYH.RIISMENFRR.P......NFELVADILFWLAQKYDPNSDIS.DNIDEERHRVEFIKQITTLFV..............SKARLKINPKRLYMADVYAVQEILKISTFLYKAQVSP........--PADEEEI.H---..........................................................DFSLPSK.L...SN.IKSH...KLLA.QEITDLATRLYDQLGKEDE.................................VKVAREKALQflsnv........srggnSQSEQ....SQIQKCIQ.TILKQQDSNIQEMSKYVGGLERDQKQLEEKIKRKTKELEQAEKRLKGMT............SVK..PAYQEEYDR....QEYELEKLYQIYVEKFRNLVYLEHVLDAQNRQA---eleq.......................................
U3JP63_FICAL/14-283                  ......................RALGYP.RLISLENFHT.P......NFMLVSEVLLWLVKRYEPQSDIP.GDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYGAMSTQg......gEPAHLPEED.STKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGAVLYDLLGKEVE.................................LREARTESIA..................RPLEI....NEAEKVMK.IAINSVLGEVQKTKDMLNNVALDEASLEAKIEKRKLELERSQKRLQTLQ............SVR..PAFMDEYEK....IEEQLQKQYSTYLEKFRNLTYMEQLLDDHRRAEQE-m..........................................
G3WRK7_SARHA/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAVKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
A0D714_PARTE/14-286                  ......................RALGYH.RIISMENFRR.P......NFELVADILYWLVLKYQPDADIS.DNIDEERHRVEFIKQITTLFV..............SKARLKINAKRLYMADVYAVQEIFKISTYLYKAQISQ........--PAEEDEV.---H..........................................................EFSLPSK.L...CN.IKSH...KVLA.QEITDLATRLYDQLGKEDE.................................VRVAREKALQflqnv........srggdSQSEQ....SQIKMCIE.QILKQQDSNIQDMSKYVSGLESDQKQIDEKIKRKAKELEQAEKRLKGMT............SVK..PVYQEEYDI....QEYELDKLYQIYMEKYRNLVYLDNVLDAQNKQA---eie........................................
E2AT63_CAMFO/3-271                   ......................RVLGYP.RLISIANFRV.P......NFPLVAEILVWLVKQFDPDIDIP.NEHDTEEQRVALIRNVAEFMA..............LKTNIKLNTKKLYQADGYGVKEILKITTMLYDAQNSS.......sIKENRSGNN.QSTV..........................................................NFDISDK.I...SE.LKTT...RQLA.SQLTINGATLFDLLGREME.................................LREIRNTKIA..................RQFDT....SEIEAALK.DVIENTSKEIEETKKQIDNVKDTEQNLDARIERRKTELDRNQKRLHTLK............KVR..PAFMEEFEK....LEIELRSLYNDYLEKFRYLAYLEHLYEDAAKAEQE-r..........................................
A0A067QVA1_ZOONE/14-281              ......................RSLGYT.RLISMENFRN.P......NFQLVAEILIWIVKRFDPDADIP.SEIDTEQDRVILVKSAAQFMA..............SKANIKLNTKRIYQADGYAVRELLKVTSVLYSALRVN........MASLGDNSS.SLSS..........................................................PVDISSK.I...HE.LAQT...RQLA.SQITARGAGLYDLLGKEVE.................................MRELRNMCVS..................RQLEM....AEVEASVR.KALETVKMEIANKKQQMENVSASEANLDSKIEKKQTELDRNKKRLQTLK............KVR..PAFLEEFER....LEVELQQLYQDYLVRFRCVAYLEQQQEEAEQAEHE-r..........................................
CLUA1_HUMAN/14-283                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
D8RNG9_SELML/6-274                   ......................KSLGYPgDGLSMESFRT.P......HFDTVASCIRWLLPRYDPEVQLH.GDVSTEEGRIAFLKSAGRVMF..............LKTRMKLNLRSLYMADSNATAELLQVSTLLQQAIASA........SSEKVCENF.VFLF..........................................................LTTLFKR.A...FD.VKAA...RSLV.LEIIKAGATLYDDLATEMQ.................................LQGERNMAAS..................TNTDI....EQIENLVR.EGTFSLLQTVSSVEQQQHSCEKDEKSLSITHEKRKVELERCKKRLSVLE............NVR..PAYLDEYEV....LQSELQRLFGVYLEKFHNLRWLESQLETHNQEEQEK...........................................
CLUA1_DANRE/14-283                   ......................RALGYP.RLISMENFRS.P......NFPLVAEILIWLVKRYEPQMEIP.SDVDTESDRVFFIKAVAQFMA..............TKAHVKLNLKRLYQADGYAVKEMLKITSILYNAMKTKe......nAGGDQNNDE.NSKF..........................................................KFDLGSK.I...AD.LKLA...RQLG.SEITAKGAALFDLLGQEED.................................LRESRTAAIA..................RPLEI....TETERAMR.AAVKDVTESIQMTKDLLNNVSSDEASLEAKIEKKKQDLERNQKRLQTLQ............SVR..PAFMDEYEK....IEEDLEKQYQTYVEKYRNLSFLEQQLDDYHRVEQE-r..........................................
K0TFE1_THAOC/4-195                   .................gkvak------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.---A...QALQ.LDLDELSKRISQSLLNEIA.................................ERGQVADKFF..................DTTDIvssvATLKENIQ.EEIEDWNQQEKSFLLRSKLLISKQRGLEDKIQKRRHELERRYARWDSLK............HIR..SAYADEYEQ....LEDELRLEYESHVLKLRNIDFLESELLQFRQN----naheqmvsrndikkrqkeffleenrrlhcslreegdsistslr
H2TL69_TAKRU/14-283                  ......................RALGFP.RLISMQSFRT.P......NFPLVAEILIWLVKRYEPTMDIP.TDISTETDRVLFIKAVAEFMA..............NKAHIELNTKNVYKADGYAVKEMLKVTSLLFSAMKTTe......aALGDRNEED.NVKF..........................................................KFNITSQ.T...SD.LKAA...RQLA.SVITSKGASLCDLLAKEVD.................................LKESRSVAIA..................KPFEM....NEIEKALK.AAIKEDLESLETTKDMLSKLASDEPSLDSKIEKKKQELERNQKRLRTVQ............SVR..PAIMDEYEK....IEEELKEQYELYVKKFRILCCLESQLESYHRLEQE-r..........................................
D8RLZ5_SELML/6-274                   ......................KSLGYPgDGLSMESFRT.P......HFDTVASCMRWLLPRYDPEVQLH.GDVSTEEGRIAFLKSAGRFMF..............LKTRMKLNLRSLYMADSNATAELLQVSTLLEQAIASA........SSEKVCENF.VFLF..........................................................LTTLFKR.A...FD.VKAA...RSLV.LEIIKAGATLYDDLATEMQ.................................LQGERNMAAS..................TNTDI....EQIENLVR.EGTDSLLQTVSSVEQQQHSCEKDEKSLSITHEKRKVELERCKKRLSVLE............NVR..PAYLDEYEV....LQSELQRLFGVYLEKFHNLRWLESQLETHNQEEQEK...........................................
A0A096NLC4_PAPAN/14-283              ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGLEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQE-r..........................................
A7SE98_NEMVE/14-282                  ......................RSLGYP.RLISMENFRS.P......NFALVAEVLIWLVKRYDPNVELP.MDVETEQDRVLFIKAVAQFMA..............TKAHIKLNTKKLYGADGYAVKELLKVTSVLYNAMKSN.......vTDDEAEPSD.VTSL..........................................................TFDISSR.I...SD.LKAS...RQLA.SEITTRGAALYDLLGHEVE.................................LRDIRTRAIA..................KPLEV....NELENGIK.KSISLAQDDIRKTTQMLDNIASDEANLEAKIDKKKQELERNQKRLRSLE............SVR..PAFMDEYEK....LEEELKKVYETYMEKHRNLSYMEQLLDDVNRAEQD-r..........................................
CLUA1_CAEEL/14-304                   ......................RSLRYP.RLMSIENFRT.P......NFQLVAELLEWIVKKFEPESNLDaHEVQTEADRVAFIKNAVLLML..............QNSRIKMNPKKLYQADGHAVQELLPAMKILYQAKAED........-PNTDNSPK.WTQV..........................................................KNKLSSK.M...QE.VRIT...RQLS.SQLPETGALLSELLSRQEF.................................ISQQHERAAS..................RAVPL....AEAEKVLQ.ATVQNIAQETEQLSNKLNNVASDEAELDEKIERKKREYEQLQKRFAKLQ............SFR..PQYMDEYER....FEERLKKLYEVYVLNFRNLSYLRKVHDDLARSERQ-rqeelekamrmavekmrleqekkd...................
H2WEP9_CAEJA/1-59                    .....................m------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-----------------------------------------QKRYAKLQ............SFR..PQYMDEYER....FEERLKKLYEVYVLNFRNLSYLRKVHDDLARSERQ-rqe........................................
I3MBH8_SPETR/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYNAMKTKg......mESSKIGEED.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKEILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKHYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
B3MRF1_DROAN/14-289                  ......................KLLGFP.RVFPLQALAS.Phg.slaSFHIVAELLQWLAGLMEPGASLP.GGVESEEHRVLLVRSATEFFV..............TKAAIRLNPRKLYAAASVTAAELQKITRLLTAPGGQT........ETDHEDEEQ.RDQYrs......................................................lnPVDIGDK.M...ED.LRKA...RELA.TDLTQRGATLYDLLSKELL.................................NKEARTAQAQ..................RPLEL....LSVERTLK.NAIQSNQLRLQSSKAQLEATRVELNALGSKLQRRKAELERTRQRLEALH............RIR..PAHMAEFED....CEKELQQLFQRYFLRLHVRDALRFQLESRTKR----atp........................................
U4UQI8_DENPD/14-285                  ......................RALGYP.KLVSMESFRK.P......NFPLVADLLVWLSKRFDPDVDIP.LEIATEENRVKLIRNSAQFMA..............LKGSIKLNTKRLYQADGYSVKELLKIASLLYDALNVN.......lD-ENEEDQM.NEESfs......................................................yrDFDISDK.V...ND.LKLS...RQLA.SEITSTGATLFDLLGKEVD.................................LRSARQRSMG..................RQFEL....SEVEAGVK.KAIESINQEISETKQLIDNVAATEASLDSKIERRKIELDRYEKRLQTLK............KVR..PAFLEEFTE....LEQELEQLFVQYSVRLRCLNQLEKQFSDSERIQ---lek........................................
C1MHX5_MICPC/14-292                  ......................RSLGYP.RIVSVENFRT.P......NFELVADCLEWLAQRYDGGAVVE.DDISTETDRVRFLKSVAAVFL..............SKARIKLNLKRLYAADGLAVKELLKIANLLYQATAKA........DEDDADEEA.SGGT..........................................................AFALDAS.A...FD.VKTT...RALA.SEITRLGATLHDALGEEER.................................LRDARLSATR..................KNMDI....EEIESQIS.EQIATVRENAANVERAMAELTEDESSLARQIERKRAELERSEKRLATLEsgafytkvfhppSVR..PAYMDEYER....LEPEMDELHAAYIERHRNLTYLESELEKIERDEE--d..........................................
L5KHC7_PTEAL/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAVAQFLA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSKIGEDD.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
A0A093BJS0_CHAPE/7-276               ......................RALGYP.RLISMENFHT.P......NFLLVSEVLLWLVKRYEPQTDIP.PDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYGAMNTKe......eEYADVSEED.SSKF..........................................................KFYLGSK.V...AD.LKAA...RQLA.SEITHQGASLYDLLGKEVE.................................LREARRESIA..................RPLEI....NEAEKGMK.IAIDCVLEQVQKTKDMLNNVALDESYLEARIEKQKLELERSQKRLQILQ............SVR..PAFMDEYEK....IEEQLQKQYSTYLEKFRNLTYMEQLLDDQRQTEQE-m..........................................
J9F6H1_WUCBA/1-118                   .....................i------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................---ERNKALS..................FSLSL....SDGEKAIL.QAIQAIQEELAIINQNLQNVSSDEAALDAKIERRKKEYEQQQKRLAKLQ............SFR..PQCMDEYEK....YEMKLKQLYAIYVSKFRNVSFLQGLQNEFDRAEHE-r..........................................
H3C5F4_TETNG/14-283                  ......................RALGYP.RLISMQSFRT.P......NFPLVAEILIWLVKRYEPATDIP.TDISTETDRVLFIKAVAEFMA..............NRAHVELNTKNVYKADGYAVKEMLKVTSPLHSAMRTTe......tALGDQIEED.NARS..........................................................KISVAPQ.S...SD.LKAA...RQLA.SSVTSKGASLCDLLGKETD.................................LKDSLSVAVA..................KPFEI....NEIEKALK.AAITEDLERLDKTKDMLAKLVSDEASLDGKTEKKKQELERNQKRLRTVQ............SVR..PAIMDEYEK....IEEELKEQYELYVKKFRTLCYLESQLEALHRLEQE-r..........................................
I1GEH0_AMPQE/14-282                  .....................q-TLGYP.RIISMENFRE.P......NFTLVAEILIWLIQRYDPTAEIV.TDVDTEQDRVLFIKSAAQFMS..............TKAHIKLNTKKLYGADGYAVKELLKISSLLYSAMRSN.......dDKESKDSNV.ASSF..........................................................HSSLTNK.M...TD.LKAC...RQLA.SEITTKGASLYQLLGQEVD.................................LREARHTAIS..................RPVDI....DSIEKGIE.RSIEAVNDETARMKQRMDNAASDEKTLEIKIEKKGQELERNQKRLKTLE............NVR..PAFMDEYER....LEGDLKQVYEMYMEKFRNLSYLEQQLEDQRKVEQD-m..........................................
A2DLL3_TRIVA/14-275                  ......................RILGYP.HPVGIDSFDT.P......NFGLMANLLHWLATLYDPEIVIL.AELSNEHGRVEFVRGIVQQMA..............IKSGIRLNPRKLYASDRFAVRELLKIAVPIYRGISSS........--GR-----.LADT..........................................................KTTSFPK.N...QN.TQKI...SQLS.ATVPRHSVELYDQLDKEVQ.................................IRETRTKILS..................TVPSL....DEVEKSVL.ESVDGAAARLEQLTKELDRLNSDEDALNTKIKQRKHEYERQSKRLMSVQ............TIR..PAYMEEYEM....LEQELGELFKTYFQHYRNVDYFEKEISKQAEKV---kknn.......................................
F7ASW0_MONDO/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAVKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
A0A067R4S8_ZOONE/14-84               ......................RSLGYT.RLISMENFRN.P......NFQLVAEILIWIVKRFDPDADIP.SEIDTEQDRVILVKSAAQFMV..............SGILV--------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------qllev......................................
T1G7F4_HELRO/14-291                  ......................RALGYK.RLISMENFKK.P......VFPLMADIMTWLALRFEPNADIP.RDIESQQDRIIFIKYITEFMA..............TKVSTKVNPKKLYESDGYSVKEMIKVSQILYQAMLSSadgdgangDGHDDDDDG.ITALs........................................................vMSDLSSK.V...HE.LKEA...RLMT.SELIRKGALLHDLLAKEVD.................................LKLARLNALS..................KQLEL....GDVERLLA.ESEKSVQTELAKIMSLIESIASDEANLEAKIEKKRAELERNKKRYESLQ............GVR..PAYMDEFER....CEEELQQMFSEYLDKQKNSSFLELIYEKYNKIEQD-f..........................................
A0A024MFI6_BRUMA/128-217             ..........nllqiillrtpv------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.------------INHNLQNVSSDEAALDAKIERRKKEYDQQQKRLAKLQ............SFR..PQCMDEYEK....YEMKLKQLYAIYVLKFRNVSFLQ-------------glqvws.....................................
G5B1H2_HETGA/78-347                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSKVGEED.ISKF..........................................................KFDLSSK.I...AD.LKAA...RQLA.SEITAKGAFLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NEIEKVMR.IAIKEILSQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHQMEQE-r..........................................
A8XZA7_CAEBR/3-82                    ......................RTLRYP.RLMSIENFRS.P......NFQLVAELLEWIVKKFEPDASLDaTSISTEAERVEFVKNAVLLML..............QNSRIKMNPKKLYQ-----------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------vrit.......................................
B4NC22_DROWI/14-290                  ......................KLLGFP.RVFPLQSLAShPstgslaSFHIVAELLQWLAGLMEPGSILS.GGVESEDQRVQLIRSATEFFV..............MKSAIRLNPRKLYAASAVTALELQKITRLLIAPTQTDa.....erDEEREREQY.RSLN..........................................................QVDIGDK.M...EE.LRRA...RELS.SDLTQRGAALYDLLSKELV.................................NKEARLAQAQ..................RPLEL....VSVERILK.NSIQANQLKLQTSRSQLESQRVELNALQSKLQRKRAELERTKQRLEALQ............KIR..PAHMAEFEE....CEKELQQLFQRYFLRLHVRDSLKHHLEGRNKKS---tp.........................................
H9JVX8_BOMMO/2-194                   ......................RVLGFP.KPISLESFRI.P......NWELVEECLRWQAARVDPDAVLA.GGRGSVEQRVSIVTHAVSLFH..............SRANLKLNGKKLYGADGWAVRELLKVATLLRAALESP........--GSEDQSD.STPL..........................................................SYDISNR.L...GE.IKQA...RALA.TEITAQGAFLYDLLTKEPE.................................NKAAEEQQTAim.............qliHKYEA....E-------.-------------------------------------------------............---..---------....------------------------------------dvlgkisgsdemessdesqdaeeakp.................
T1H9I2_RHOPR/87-373                  ......................RTLGFP.RLISLENFRI.P......NFTLIADILIWLVKRFDPDADIH.DSYTTEEDRILLIRTAAEFMA..............VKANVMFNTKRLYQADGYAVKELLKITTLLYNALLAN........---NKDSNW.LPSF..........................................................NSDISTY.I...QD.LKMS...RDLA.SQVTIKGASIFELLRKEVD.................................LRDIRNSSIS..................TLIEM....NRIESAVK.EAVEFAKTSIANTKSLIENVSATESSLDAKIEKKQVELERNQKRLQTLK............KVR..PAFLEEFEK....LEAELQTLYQEYVTRTRCISYLEQQHEEATLIEQE-rmqqrqretkkmveemqqadarn....................
A0DJV3_PARTE/14-289                  ......................RALGYH.RIISMENFRR.P......NFELVADILYWLALKYDPNTDIS.DNIDEERHRVEFIKQITTLFV..............SKARLKINPKRLYMADVYAVQEILKISTFLYKAQVSS........--PAEEDEV.---H..........................................................DFSLPSK.L...SN.IKSH...KALA.QEITDLATRLYDQLGKEDE.................................VRVAREKALQflqnv........srggnSQSEQ....SYIKTCID.SILKQQEKNIQNMSMYVSGLERDQKQIDEKIKRKTKELEQAEKRLKGMT............SVK..PAYQEEYDR....QEYELEKLYQIYVEKFRNLVYLEHVLDAQNEQA---eieqrk.....................................
Q05AZ5_XENTR/14-283                  ......................RALGYP.RLISMENFRS.P......NFPLVAEVLIWLVKRYEPHTDIP.VDVDTEQDRVFFIKAVAQFMA..............TKAHIKLNTRKLYQADGYSVKELLKITTVLYNAMKSKg......mESTQLEDQE.TSTF..........................................................KFNLGSK.I...SD.LKMA...RQLA.SEITSKGATLYDLLGKEAD.................................LREQRTAAIA..................RPLEM....NDTEKVLR.TSIKEVLEQVQKMKDLLSNVASDEQNLEAKIEKRKQELERNRKRLQTLQ............TVR..PAFMDEYEK....IEEELQKHYETYLDKFRNVCYLEQQLEDYHRVEQE-r..........................................
L5MA99_MYODS/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIL.SDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mESSKIGEDD.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITYKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
G1LVW2_AILME/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFVKAIAQFLA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEDSKIGEED.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSRGASLHELLGKEVE.................................LRKLRTEAIA..................RPLEI....SETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNQKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
F6RMJ6_ORNAN/7-273                   ....................dt-----P.RHISMENFRT.P......NFGLVSEMLLWLVKRYEPHTDIA.ADIETAHDRVFFIKAIAQFMW..............TEINVKINYRDIHRESGGGMGRXLKITSVLYNAMKTKr......mEGPEIEEED.TSKF..........................................................KFDLGSK.I...AD.LKAA...RHLA.SEITSKGASLYDLLGKEVE.................................LRELRMEAIA..................RPLEI....NEAEKVMK.IAVKDILAQIQRTKDLLNNVASDEANLETKIEKRKSELERNQKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDTYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
F6WNW0_HORSE/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTQg......mEGSKIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....TEEELQKQYDAYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
A0A068WZU3_HYMMI/2-262               ......................RTLGYP.RPISTEHFAT.P......NFPLVAEILHWLSQCMDSNLDIS.MHIDSEQDRIVFINSIAQFLS..............TKTFTKLNPKRLYEANGHAVKEILKFVKVLYSALKLN........----KVTGV.VNDE..........................................................DLSLSEA.V...KQ.PQLI...RSLA.GHLTSIVTSLKSFMSKEAD.................................FRKSRKESIE..................RHLDV....EWVEKCLN.DATDITLGEVSNLEKALSDIKEDEKALDGKIEKRRHELERNQIRLSTLK............SVR..PTYMDEYEQ....LEEELKSHYETYLDHFRNISYLESL-----------rgeisfsd...................................
U1MSR8_ASCSU/14-314                  ......................RALGYP.RILSLENFRT.P......NFKLVAELLEWIVHRFDPNSHLP.TILDTEQERVVFIKTAVLILL..............QKARIKLNPKKLYQADGYAVQELAVVVRLLYGTAKQP........LDAEGGVAA.WNAM..........................................................RSKVNTK.V...QE.VHEC...RQLA.AQISQTGATLYDLLAKELIaavsshrlssfpffnsklefhlwtslsliimyqLQEARSKALS..................FSLDL....ADAEKAIK.QAIEAIQGELAQINRNLQNINSDEAALDGKIERKKREYDQQQKRLAKLQ............SFR..PQYMDEYEK....YEKKLKQLYAIYVLKFRNVAYLQQLQSEFDKAERQ-r..........................................
H9G581_ANOCA/3-227                   ......................RALGYP.RLISMENFRT.P......NFMLVSEILLWLVKRYEPQTDIP.SDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKSKg......mEATTVSEED.TGKF..........................................................KFDLGSK.I...GD.LKTA...RQLA.SEITSKGASLYDLLGKEVE.................................LREIIITSCA..................RPLWH....SGKDKTVQ.LIKSLISEQVQKTKDMLNNVASDEASLEAKIEKRKMELERNHKRLQTLQ............SVR..---------....------------------------------------...........................................
G1T1X1_RABIT/14-286                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDIDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYNAMKTKg......mEGSKPGEED.VSKF..........................................................KFDLASKeA...AD.ARDS...GQRGrGEAEGRSCLVWRRGGHRAQ................................pREELRTEAIA..................RPLEI....NETEKVMR.IAIKEILVQVQKTNDLLNNVASDEANLEAKIEKRKLELERNRKRLKTLQ............SVW..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
U6MIW6_EIMMA/80-354                  ..................raam------.----------.-......--------------------SVV.QEVKTHKDQLKLLQNLVAFML..............QRVGVALELQALFRAGAEAVSELLRLSETLADAAKQA........SHDQASKKV.EKTTvhlqaven.........................................gegrvrreePSEISQN.F...KEaLHTV...QAQV.EKVIVSVQSFYGKEQTEER.................................RKT--EEFLQallapegptgadvvaaaaVTASR....SGSRALLG.EQLDRSRQALMEVERRNEVLASQVQELKEKIRGEEQNADRLSKQLLLLG...........gSQN..PALAATEEQqqreMQEQLRQLYIQYARRSALCDTLTASVEAMA------graeaaa....................................
W5JBA3_ANODA/14-284                  ......................KLLGYP.NHIPLSVLTT.Pyg.gpeSFKAYSDILQWLINRLEPNLVLA.GGTRSEQERVLFVRSATEFLV..............TKSSIKMNPRRLYASSMAAAQELLKVTSLLIASPKIT........--RHEEESI.KSHL..........................................................EIDFSDK.M...ND.LKMV...RGLS.SELTNKGAVLYDLLKKELV.................................NREIRNAQST..................RPIEL....ATAEKVIK.GAISTVQSKLSGSTTALESLRNENTNLESKMRRKASELERSRQRLQALQ............KVR..PAYLEEFEK....LEQELKGLYEQYIVRIKCVDTLRAQIISKNRTP---tpt........................................
V8NYL6_OPHHA/33-245                  ....................kr------.----------.-......-----------------------.-------------------LA..............TKAHIKLNTKKLYQADGYAVKELLKITTVLYNAMKSKg......mESTAMGEED.VGKF..........................................................KFDLGSR.I...SD.LKTA...RQLA.SDITSKGASLYDLLGKEVM.................................LRELRTEAIG..................RPLEI....NETEKVMR.VAIKDILEQVQKTNDMLNNVAADEASLEAKIEKRKSELERNHKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYSCYVEKFRNLTYLEQQLDDQHRMEQE-r..........................................
B7PGD6_IXOSC/9-273                   ......................RALGYP.RLVSLENFRN.P......NFPLVAEILRWLLKRYDPDIEMP.TEIDTEQDRVIFIKAVAHTMA..............TKAHLKLNTRKLYMADGYAVKELFKVTSLLYDAMKTK........---SFDPES.AEGN..........................................................LRNVSHQ.L...SD.LKLT...RQLA.SEITHHGAQLYDHLAKEAE.................................LKEMRAATLA..................KQLEI....TEIEKCLQ.DATRL--EETAQLHRRMETVAADEANLEVKIDKKKADLERNQKRLATLR............AVRqvPAFMDEYER....IEEELSQVYGQYVVKIRCLAYLEEQLEELERTQK--ie.........................................
V8NYL6_OPHHA/3-38                    ......................RALGYP.RLISMENFRT.P......NFMLVSEILLWLVKRLA------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------tk.........................................
G3WRK6_SARHA/14-286                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAIAQLCFv...........aaTKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAVKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
Q4DIB8_TRYCC/14-279                  ......................RLLGYP.NLISMESFRN.P......NVELVADCLFWLIKRYEPSAEIV.YEIEREGDRIFFFKQICEVAL..............AKGQIKLNIKKLYQSDGNAVQEMLILASVLKKAMNAT........--EAEEADY.TSVQ..........................................................QMVAQKN.V...KD.AKRV...QQLC.SDLTSDGSALFFLIEEEIS.................................QRGERQRVLS..................RATEV....GEFERRLR.DVLANVGKQVEQLQTTIMNLSADETTLEQKIESKKTQLERAQKRLKSLM............AVR..PAFMEEYEK....HEGDLQSQFVVYLEQYRNLEYLEHELAKFNAAED--av.........................................
A0A0B2UWT1_TOXCA/14-282              ......................RALGYP.RLLSMENFRT.P......NFKLVAELLEWIVRRFDPNTRVS.TILDTEQERVIFIKSVVLILL..............QKARIKLNPKKLYQADGYAVQELAVVIRILYDTMKQP........LDADGGAIA.WNTM..........................................................RSKVNTK.M...QE.VRMC...RQLA.SQIPQSGATLYDLLAKEVI.................................AAEARSKALS..................FSLDL....ADAEKAVK.QATEAIQDELAQINHNLQNISSDEATLDAKIERKKREYEQQQKRLAKLQ............SFR..PQYMDEYEK....YEKKLKQLYAIYVLKFRNVAYLQQLQSEFDKAER--lrn........................................
CLUA1_MOUSE/14-283                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDIETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSNVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDLLAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....VEEDLQKQYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
F2URB7_SALR5/14-146                  ......................RTLEFP.RLVSIDNFRQ.P......NFPLVAEILIWIIRRIDATATIP.TDVEDETDRVLFVKAVAQFMA..............TKLHLRLNTKRLYEADGHAVKELIKATSLLYNALKSQne....eaPQGGES---.---Gppv....................................................tlsDFNLTSK.I...GE.LKV-...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------ragag......................................
F2URB7_SALR5/145-192                 ...................agv------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..PAFMDEYEK....LEAELAKTYETYIEKFRNISYLEQELEQHNRTEQD-k..........................................
F6STI1_MACMU/30-299                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGVEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQE-r..........................................
G3T0T0_LOXAF/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPHTDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mESSKIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAVA..................RPLEI....NETEKVMR.IVIKDILAQVQKTKDLLSNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYER....IEEELQKQYDIYLEKFRNLTYLEQQLEDHHRMEQE-r..........................................
Q7QF08_ANOGA/14-284                  ......................KLLGYP.NSIPISVLST.Pyg.gpeSFKAYSDVLQWLINRLEPNLVLA.GGTRTEQERIQFVRSATEFLV..............TRSSIKVNPRKLYASSVAAAKELLKVTALLLSSPKVT........--GQEEELI.KSHV..........................................................EIDLSDK.L...DD.LKKV...RGLS.SELTNRGAALYDLLQKELL.................................NREVRNVQST..................RSLEL....GATEKIIK.GAIGSLQSRLASARAALDGLRADNANLAAKSARKASELERSRQRLQALQ............KVR..PAYLEEFEK....LEQELKALYEQYIVRIRCVDALRSQLISKNRTP---tpt........................................
A0A077ZJX2_TRITR/36-308              .....................e-ALNYP.NPLSFGSYRC.P......NFPLTAEILRWLCNCYGDDHDLP.KDISTEKNRALFVKAAALYMY..............RQTGMKLNPRKIYQANRSAIKELLRIVAPLYQAYRTLsv...sgfQRDDDANSR.FSNL..........................................................NNSLQEK.L...AE.LPKQ...RTTM.SELTEISAAIYDLLSQDTE.................................AREYRSNAMA..................KQMDI....TELEAVLR.QAHVAMQEEIKETDRILQSIANDEQAMDNKIIKKQAEIDRLKKRLEQLQ............SVR..PAYMNEYES....LELEHQAHYDLYVQKFRNLVYLQSLLMNIEAAE---iek........................................
A0A068Y292_ECHMU/3-271               ......................RTLGYA.RLISLESFRA.P......NFSLMAEILRWLALRFDPNADIP.KFLDTEQDRVIFIKVIVQFMV..............VKAFIKLNAKRLYKADGCAVKEMLKIVKLLHSSLKFG........ERTGDDEQL.NLNF.........................................................aEILSIER.L...KQ.LQHT...RFLA.SQLTSSGASLYSHMSHEVD.................................FRQIRNDAIH..................RQFDI....EFVEKCLS.GACDAVRAEIAKAESALNNIRTDENNLNGKIEKKRGELERNQKRLLTLQ............SVR..PAYMEEYEQ....LEEELNVYYETYLTQFRNLSYLENLKEEIMRSED--tk.........................................
H0Z087_TAEGU/13-282                  ......................RALGYP.RLISMENFHT.P......NFMLVSEVLLWLVKRYEPQSDIP.GDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGHAVKELLKVTSVLYGAMNTQg......gERAQFPEED.STKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGAVLYDLLGKEVE.................................LREARTESLG..................RPLEI....NEAEKVMK.IAINSVLEEVQKTKDMLNNVALDEANLEAKIEKRKLELERSQKRLQTLQ............SVR..PAFMDEYEK....IEEQLQKQYSTYLEKFRNLTYMEQLLDDHRRTEQE-m..........................................
J9P5I7_CANFA/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVRRYEPQTDIP.SDVETEQDRVFFIKAIAQFLA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSQIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
D0N834_PHYIT/14-294                  ......................RSLGYP.RPISMENFRT.P......NFELVSDLLYWMVKKYDPSSSIT.EEIDTEDDRVEFLTQVATEVL..............AKARIRLNPKKLYAADGFAVKELIKLARVLYEASRIDl.....aaQQEPDDDDD.EVSV..........................................................KSMLGSR.V...KD.PKAT...RQLA.SDITQSGAKLYDLLDTELD.................................VRDARQQAIRfldal........stnheNSSEQ....KFLERSIQ.DILVNLQENVELTERQVVELDAEEKALAAKIKKAQTDLERSEKRLKSLQ............HVR..PAFMDEYEK....LEKELERQYAIYCERFRNLDYLQRELDLHNSREMK-k..........................................
H2QAG8_PANTR/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRAEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
Q16MH9_AEDAE/14-284                  ......................KILGYP.NNIPLSVLNT.Pyg.gpeSFKAYYDVLTWLIGRLEPNLILA.GGIRSEQDRVLFVRSATEFLV..............TKSSIKVNPRKLYASSAAAAKELLKVTSLLIASPKVT........--GADEESI.KSHV..........................................................EIDLSDK.M...DD.LKKV...RGLS.SELTNRGAALYDLLKKELV.................................NSETRMVQST..................RPLEL....ATVEKVIK.SAITSLDSKLVASKASLESLKAENGNLTAKIQRKSSELERSKQRLQALQ............KVR..PAYLEEFEK....LELELKNLYEQYIIRIRCVDALKSQLISKNRTP---tpt........................................
I3L455_HUMAN/14-49                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKR--------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------pprh.......................................
I3L3S9_HUMAN/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
C3Z7T3_BRAFL/14-283                  ......................RALGYP.RLISMENFRT.P......NFPLVAEVLIWLVKRYEPNADLP.MDVDTEQDRVIFIKSVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTAMLYNAMKTNt......gQQEEEQEEE.TTAM..........................................................SFDISSR.I...AD.LKAS...RQLA.SEITTKGASLYDLLGREVE.................................LREQRSVAIN..................KPLEI....NEIEKHLK.VSIRAVEQEIKKTEHMLNNVASDEANLDAKISKKKLELERNRKRLQTLQ............SVR..PAFMDEYER....LEEDLQKQYESYLQKFRNLGYLEQQLEEHNRAEQD-k..........................................
Q228X0_TETTS/14-287                  ......................RALGYS.RLISMENFRK.P......NFELVADILYWLATRVDPQADIP.EQIDEERHRVEFIKAIATLFA..............SKIRIKLNTRKLYQADGHAVQEIIKVATVLYKAYNSS........--PGDEEEN.---A..........................................................GFTLPSK.L...SN.IKAH...RAIA.NDITEIAQKLFDSLNKEND.................................LQQHRDKALQfldni........srnleSNSEQ....AYIEQCVR.EIIKQQDQGIIDMQNYVSNLEKEQKNIEDKTKKLTIELQKQQTLLYNLK............VMK..PAYMEEYIR....LEYELEKLYQIYIEKFRNLDYLENELDQYNLIEKK-kq.........................................
J9K349_ACYPI/14-279                  ......................RSLGYH.QQISMDSFHS.P......NFSLVSEILFWLAMRFEPDTNLP.QEIETSEQRVYFIRSIVEFFV..............LKTNVKLNVKKLYQADRNAVGELLKITELLNDALNTK........--QTYEDEG.FTKL..........................................................EINLTYK.A...NE.LKTT...RELA.SKITQKGAALFRSLEEESE.................................LRPIRDSRVN..................AALDI....NEVEQSLK.TLIQKTKKETEHTTDLIKNISATEANLDAKIAKRREDLERNSKRLQTLK............QVR..PAFLEEFED....LESELRNLYQEYITRQRCISYLEHQQEQVAQAE---lih........................................
F6STM5_MACMU/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGVEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQE-r..........................................
B3RPP2_TRIAD/14-282                  ......................RSLGYP.RLISMENFRQ.P......NFPLVAEILLWLIKSYDPNLDLP.SDIDTEQDRIFFIRSTAQLMA..............TKAHIKLNTKKLYGADGYAVKEILKITTILYNAMKAN.......kQNEENNSSE.NAKA..........................................................KFDISNK.I...TD.LKQS...RHLA.SDITTRGASVYDLLGEEPD.................................LRDQRTTALA..................RPLEL....DDLEDRVS.KSVSSVEEQHQHTERMLNNIASDEANLEAKIQKKKQELERNQKRLKSLQ............AVR..PAFMDEFEK....LEAELQKLYTGYFEKYRNLVYLEQQLEENNKIEQE-k..........................................
H3H271_PHYRM/317-597                 ......................RALGYP.RPISMENFRT.P......NFELVSDLLYWMVKKYDPSSSVT.EEIDTEDDRVEFLTQVATEVL..............AKARIRLNPKRLYAADGFAVKELIKLARVLYEASRIDl.....atQQEPDDDDD.EVSV..........................................................KSLLGSR.V...KD.PKAT...RQLA.SDITQSGAKLYDLLETELD.................................VRDARQQAIRfldal........stnneNSSEQ....KFLERSIQ.EILVNLQENVELTERQVVELDAEEKALAAKIKKAQTDLERSEKRLKSLQ............HVR..PAFMDEYEK....LEKELERQYAIYCERFRNLDYLQRELDLHNSREMK-k..........................................
B4H2Y5_DROPE/14-287                  ......................KLLGFP.RVFPLQSLAN.Qhg.slaSFHIVSELIQWLAGLMEPGTVLS.GGVETEEQRVLLVRSATEFFV..............TKSAIRLNPRKLYAAAAVTASELQKITRLLIAPSQTE........AEREEEERD.QYRSl........................................................nQVDIGDK.M...EE.LRRA...RELS.SDLTQRGAALYDLLSKELQ.................................HKESRQTQAQ..................RPMEL....LSVERTLK.NATQASQLKLQSSRAQLEAARVELNALNSKLQRKRAELERTKQRLEALQ............KIR..PAHMAEFEE....CEKELQMLFQRYFLRLHVRDALRSQLEARTKRT---tp.........................................
F9WCG0_TRYCI/14-278                  ......................RLLGYP.NLISMESFRN.P......NVELVADCLFWLVKRYEPSAEIV.YEIEREADRVFFFKQVCEVAL..............TKGRVKLNIKKLYQSDGNAVQEMLILANILKKAMNTT........--ALEELDH.SSLQ..........................................................QMIAQRN.V...QD.AKRV...QQLC.SDLTNDGSSLFFLIEEETK.................................QRSDRQRVLS..................RATEV....GEFERRLR.DVLKNVTTQVEQLQATIVNLGADETTLEQKIESKKTQLERTQKRLKSLN............AVR..PAFMEEYEK....HENDMHSQFVIYLEQYRNLEYLEHELSKFNAAED--a..........................................
A0A024MFI6_BRUMA/6-133               ......................RVLGYP.RLVSMENFRT.P......NFKLIAEILEWLVHRYDAQISIP.LVIETEQERAFFIKSATFYIL..............QKARIKLNPKKLYMADGYAVQEIAVVVRNLYEITRHT........-SDFDQNAT.ISSM..........................................................RNIISSK.I...S-.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------llfnllqii..................................
I3L1J4_HUMAN/73-201                  .....................m------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDTYLE----------------------...........................................
C1EA98_MICSR/14-94                   ......................RSLGYP.RIISVENFRN.P......NFELVADCLDWLVQRFDESADID.DDISTETDRVTFLKNVSKVFM..............SRARLKLNIKRLYAADGYA------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------r..........................................
T1FVV9_HELRO/146-332                 .......nhvisskcrdshsdn------.----------.-......-----------------------.---------------------..............-----------------------------------TD........NNDDDEDDR.TYTL..........................................................LTNLASR.T...DE.LREA...RVLV.KEITEMAANLYFKLAKEVD.................................LSEARFHALT..................RHYDL....DSIEHLIG.EQIKLTMKETLDTEKLLGRQKADKLRLNEKFERKAVEMDRCLKRYDTLI............SIR..PVYLKEFES....LEVEFEDLFRAYVDKHKNVAFLENLNNRYEMVEQ--hc.........................................
B8C1X8_THAPS/1-170                   .................mscqq------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................----SRL.L...DD.AKRV...QSLA.AKISEIGTTLQGLLKNEAE.................................DSIERRRAIDflnsa........tlsgtSNSEK....QHIEATLT.RLLASTNDEVEQLDQQCKMLLSSVKGMREKIRKKTIDLERNVARLESLE............SVR..PAFMDEYEQ....LEEELQVEYERYMVRFRNVDYLKGELRSFSNAAK--ekke.......................................
H3AG34_LATCH/1-211                   ......................------.----------.-......-----------------------.-------------------MA..............TKAHIKLNTKRLYQADGYAVKELLKITSVLYNAMKTKg......mDNSETAEDD.GGKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SDITSQGASLYDLLGKEVE.................................LREMRTAAIA..................RPLEI....NETEKAMR.SAIKDTLENIQKTKDMLNNIASDEANLEAKIEKKKQELERNQKRLQTLQ............SVR..PAFMDEYEK....IEEDLQKQYNIYVERFHNLAFLEQQLDDYHRMEQE-r..........................................
Q4CP52_TRYCC/14-279                  ......................RLLGYP.NLISMESFRN.P......NVELVADCLFWLIKRYEPSAEIV.YEIEREGDRIFFFKQICEVAL..............AKGQIKLNIKKLYQSDGNAVQEMLILASVLKKAMNAT........--EAEEADY.TSVQ..........................................................QMVAQKN.V...QD.AKRV...QQLC.SDLTSDGSALFFLIEEEIS.................................QRGERQRVLS..................RATEV....GEFERRLR.DVLANVGKQIEQLQTTIMNLSADETTLEQKIESKKTQLERAQKRLKSLM............AVR..PAFMEEYEK....HEGDLQSQFVVYLEQYRNLEYLEHELAKFNAAED--av.........................................
B4JNU9_DROGR/14-291                  ......................KLLGFP.RVFPLQALAT.Qhg.slaSFHIVAELLQWLAGLLEVGAVLA.GGVETEDQRVLLIRSATEFFV..............TKSGIRLNPRKLYAAAAVSAMELQKITCLLIAPTQTKgee..rdeE--RERER-.---Dqyr....................................................slnQVDIGDK.M...DE.LRRA...RELS.SDLTQRGAALFDLLSKELV.................................NKEARLAQAQ..................RPMEL....LGVERTMK.NAIQASQLKLQSSHAQLENGRVELNALNSKLQRKRAELERTKQRLEALQ............KIR..PAHMAEFEE....CEKELQQLFQSYFLRLHVRDALRTLLETRTKR----srg........................................
G7Q0C9_MACFA/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQE-r..........................................
M3YUI1_MUSPF/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAIAQFLA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSKIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSRGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
E4XZK8_OIKDI/1-246                   ......................------.RIVSMDSFRE.S......NFSLTADLLIWLTEIYEPRAMIP.KKIDTEHDRVALIKFVANTFL..............TKQHIRLNTKRLYLADGYAVKELLKLISILVEAIQEP........--PIDGNK-.-LGH..........................................................SLEGTIS.H...AT.IKEL...RERV.ANMSRSGANLYEALNAEVR.................................LRGSRQQILA..................THMEL....STIEKALK.EAAAAADKVSDSSSKKVNSVTGDEASVQTKINKKLSEIERAQKRLRQMK............QLR..PAYQDELDE....IQADLKILYDEYVIKL--------------------gvfesiri...................................
W4Y5Z7_STRPU/271-391                 ......................RALGYP.RLISMENFRT.P......NFALVAEVLIWLVKRYDPNADIP.SDTDSEQDRVIFIKSAAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKVTSVLYNAVRTKv......gGQDGDDDDG.ASAM..........................................................SFDISSK.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------e..........................................
F1RK42_PIG/1-109                     .....................q------.----------.-......-----------------------.--------------------A..............TKAHIKLNTKKLYQADGYAVKELLKIASVLYSAMTTKg......lEGSSLGQGD.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRVSG-----..................-----....--------.-------------------------------------------------............---..---------....------------------------------------vqelgsppsrsrf..............................
A4HEE7_LEIBR/14-279                  ......................RLLGYP.RLISMESFRE.P......NVELVADCLHWLIIRYEPSAEVT.FNIEREHNRVTFFKQVCEVTL..............AKGRIKLNVKKLYQADGHAVQEMLKLANVLKKAMKAT........--DAEEPDF.TALH..........................................................QMAAQKN.V...SD.AKAV...QQLC.SELTTDGSSLFFLVEAELN.................................SRGDRQRILS..................RATEV....GEFERRLR.ELLTNVAQEVDQYQQSIVNLSADETNLEQKIENKKAHLERAQKQYKSAM............ATN..PAFLKEYEN....HEKKLQAQFVNYLEQYRNLEFLEHQIAKYNAKED--vm.........................................
F4WGT1_ACREC/2-270                   ......................RVLGYP.RLISLANFRM.P......NFPLVAEILVWLVKRFDPDVDIF.SDHDTEEQRVTLIRSVAEFIA..............LKTNVKLNTKKLYQADGYAVKEMLKIATLLYDAQNSS.......nTEQNQSSSN.QNAV..........................................................NFDISDK.I...NE.LKTT...RQLA.SQLTINGAALFDLLGREVE.................................LREIRNTKIA..................RQFDT....SEIEVALK.DVIENTRKEISETKKQIDNVKDTEQNLDARIERRKTELDRNQKRLHTLK............KVR..PAFMEEFEK....LEIEFRTLYDDYLQKFRYLAYLEHLYEDAAKVEQE-r..........................................
A7SUP1_NEMVE/1-210                   .....................q------.----------.-......-----------------------.--------------------A..............TKAHIKLNTKKLYGADGYAVKELLKVTSVLYNAMKSN.......vTDDEAEPSD.VTSL..........................................................TFDISSR.I...SD.LKAS...RQLA.SEITTRGAALYDLLGHEVE.................................LRDIRTRAIA..................KPLEV....NELENGIK.KSISLAQDDIRKTTQMLDNIASDEANLEAKIDKKKQELERNQKRLRSLE............SVR..PAFMDEYEK....LEEELKKVYETYMEKHRNLSYMEQLLDDVNRAEQD-r..........................................
A8BGV3_GIAIC/14-278                  ....................tq--IGFP.RPISIDTFRK.P......DFFLVAEILHYITTVVAPSNAIA.MDIATQEDRVYFITTVVNVLQ..............TTLHLKLDSKKIYAAGPEAVRELRKIVQEVATYIGAA........-ATSTDKGT.SSAA..........................................................SVDLTLH.S...NA.LCVA...---S.SKIVEASTKLLTQLRLHVD................................dLYQRMQQAMS..................SQPDA....ASLSAAVQ.QRIKNLAAECNTLQEEVTTNKREKAKLEEQITQKKQSITHTMDRLDAIR............STK..PPFLAELEA....LEADLSKLHLEYARKFRSLLFLEGQLRANDVREQQ-r..........................................
I3K414_ORENI/14-283                  ......................RALGYP.RLISMENFRT.P......NFSLVAEILKWLVKRYEPQSDVP.TDVDTEADRIFFIKAVAQFMA..............TKAHIKLNTKRLYQADGYAVKEMLKITSVLYSAMKTKq......mALGDKVEQD.NSKF..........................................................KFDLGSR.I...SD.LKAA...RQLA.SEVTSKGASLYDLLGKEVD.................................LREMRSAAIA..................RPLEI....NETEKALR.AAIKEVLKSVDKTKDMLDNVVSDEATLDGKIEKKKQELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEDLQKHYETYVEKFRNLSFLESQLNEYHRLEQE-r..........................................
I3LL21_PIG/1-109                     .....................q------.----------.-......-----------------------.--------------------A..............TKAHIKLNTKKLYQADGYAVKELLKIASVLYSAMTTKg......lEGSSLGQGD.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRVSG-----..................-----....--------.-------------------------------------------------............---..---------....------------------------------------vqelgsppsrsrf..............................
W5M6G4_LEPOC/14-283                  ......................RALGYT.RLISMENFRT.P......NFTLVAEILIWLVKRYEPHMDIP.TDVDTETDRVFFIKAVAQFMA..............SKAHVKLNTKRLYQADGYAVKEMLKITSVLYSAMKTKg......mASGDQPEED.SSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKETE.................................LREMRTAAIA..................RPLEI....NETEKTLQ.AAVREVLHQVQKTKDMLNNVASDEVSLEAKIEKKKQELERNQKRLQTLQ............SVR..PAFMDEYEK....IEEDLQKQYEVYVEKFRNLSFLEQQLEDYHRLEQE-r..........................................
D8RLZ6_SELML/11-160                  ................hiviqw------.----------.-......-----------------------.-------------RAVASFEF..............LKTRMKLNLRSLYMADGNATAELLQVSTLLQQAIASA........----SSEKR.ALGY..........................................................AVARDNK.L...LD.HWFW...----.---IKAGATVYDDLATECS.................................FRGERNMAAS..................TNTDI....EQIENLVR.EGTYSLLQTVSSVEQQQHSCEKDEKCFEYN-------------------............---..---------....------------------------------------tremksg....................................
H3FW98_PRIPA/10-175                  .....................l------.----------.-......-------------EKFEPSALVS.ADCVNEQERVIFIKACVTMLL..............QNARIKLNPKKLYQADGYAVQELLVPMRILHSATRQR........-PSEELNAQ.WTAM..........................................................KATLGAR.M...HE.MREVtvaRQLS.SQLPQVGALLNDLLQKDLY.................................MRRERARATS..................RTVSV....QEAERSLK.LTIAAVETERKETEERKE-------------------------------............---..---------....------------------------------------gihl.......................................
G1Q0T4_MYOLU/1-85                    .....................t------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------KDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
K7ETZ5_PONAB/14-236                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............S--..---------....------------------------------------...........................................
E5S4W1_TRISP/2-300                   ......................RALNYP.KFISIESFYK.P......NFLLVADALRWICKRYCDEQEVK.FELETEQDRVIFIKSAVIFIVnf.........pfyQQTGLKLNPKKLYQADVEAIDELLKAVEPLYKAKKLNn.....isEGKRDDDQQ.QQNIqf.....................................................kqiRTTLEQK.L...SD.LGQY...HTMV.NDITDNAARLYDLLSQETEnkvsqqqqa...............vkicilsfqFKEQRTVALA..................RQVDI....DEVENHVK.HALSLLQQELKQTLKDMENIEKDELAVTSKIEKKKSELDRLQTRLAQLQ............TVR..PAYMDEYET....AEEELRRIYSQYVLKYRNLHYCKQLLERDKRQQSK-n..........................................
G3RKB1_GORGO/14-46                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVK---------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------at.........................................
U6GQG0_EIMAC/81-355                  ..............qaafsavr------.----------.-......-----------------------.-EAETPPKQLILLHHLAAFIL..............QRVGVDLDLQVLFRAEADAISELLRLAESLADGVRQAlnsqatcrEGEEEGGEI.KREK..........................................................PFEVPQT.L...RS.KEAV...QAVQ.VQVERVLVSVQNFYGEEQTqerskagrflqt........vlaseassaraavAAEAATEAAS.................sSSSSS....SSSRALLG.EQLNRGRQALADVERSNEALASHVQELKERVRSAERNADRLSKQLLLLGrs.......qdsALA..AAEQQRQRD....TQEQLRQLYVQYARKSAVCDTLTASMEANA------gsaetaa....................................
F6RR79_MACMU/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGVEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQE-r..........................................
J9ED44_WUCBA/6-80                    ......................RVLGYP.RLVSMENFRT.P......NFKLIAEILEWLVHRYDAQISIP.LVIETEQERAFFIKSATFYIL..............QKARIKLNPKKLYM-----------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------...........................................
Q4Q9V0_LEIMA/14-279                  ......................RLLGYP.QLISMESFRE.P......NVELVADCIHWLITRYEPSAEVT.FNIEREHNRVTFFKQVCEVAL..............AKGRIKLNVKKLYQADGHAVQEMLKLANVLKKAMKAT........--DTEEPDF.TALQ..........................................................QMAAQKN.V...SD.AKAV...QQLC.SELTADGSSLFFLVEGELN.................................SRGDRQRILS..................RATEV....GEFERRLR.ELLTNVTQEVDQYQQSIVNLSADESNLEQKIENKKAHLERAQKQYKSAM............ATN..PAFLKEYEN....HEKKLHTQFVNYLEQYRNLEFLEHQIAKYNAKED--al.........................................
A0CPU5_PARTE/14-288                  ......................RALGYH.RIISMENFRR.P......NFELVADILFWLAQKYDPNSDIS.DNIDEERNRVEFIKQITTLFV..............SKARLKINPKRLYMADVYAVQEILKISTLLYQSYVCP........--PADEDEI.H---..........................................................DFSLPSK.L...SN.IKSH...KILA.QEITDLATRLYDQLGKEDE.................................VKIAREKALQflsnv........srggnSQSEQ....SQIQICIQ.TILKQQEQNNQEMLKYVGNLERDQKQLDEKIKRKTKELEQAEKRLKGMK............SVK..PSYQEEYDR....QEYELEKLYQIYVEKLRNLVYLEHVLDEQIRQEE--leqk.......................................
M3WGM6_FELCA/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPHTDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......lEGSKIGEED.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSRGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
A8QFY5_BRUMA/139-229                 ..............qiillrtl------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-----LKEELAVINHNLQNVSSDEAALDAKIERRKKEYDQQQKRLAKLQ............SFR..PQCMDEYEK....YEMKLKQLYAIYVLKFRNVSFLQ-------------glqv.......................................
F0V797_NEOCL/2-164                   .................syrcm------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.---Y...SSAA.SQLVDTGASLLQALGRHRRper...........................allRRRVREFLQRlglh..........ldggADIEQ....EQIRMQLE.EQLRRAKSDLQNTQRACLDLEDEVKRTNVALSRLTQDSDRAEKRLQSLQ............HLK..PAFLEDRKK....LMAELQETYDVYIACVRNERYLEMETEERQAK----ireg.......................................
I3L487_HUMAN/3-121                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDL---.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------gs.........................................
Q9VR64_DROME/14-288                  ......................KLLGFP.RVFPLQSLAN.Qhg.slaSFHIVAELLQWLAGLIEPGATLP.GGVESEEQRVLLVRSATEFFV..............TKAAIRINPRKLYAAAAVTAAELQKVTRLLTSPGQNE.......aDNDEEDQRD.QYRSl........................................................nPVDIGDK.I...EE.LRKA...RELA.TDLTQRGTTICEMLSKELL.................................HKESLMSQAQ..................RPLEL....LSVERTLK.SAIQANQVRLQSSRAQLEAAKVELNALGSKLQRRRAELERTRQRLEALH............RIR..PAHMAEFED....CEKELQELFQRYFLRLHVRDALKSQLDLRTKR----atp........................................
Q16GM2_AEDAE/14-284                  ......................KILGYP.NNIPLSVLNT.Pyg.gpeSFKAYYDVLTWLIGRLEPNLILA.GGIRSEQDRVLFVRSATEFLV..............TKSSIKVNPRKLYASSAAAAKELLKVTSLLIASPKVT........--GADEESI.KSHV..........................................................EIDLSDK.M...DD.LKKV...RGLS.SELTNRGAALYDLLKKELV.................................NRETRMVQST..................RPLEL....ATVEKVIK.SAITSLDSKLVASKASLESLKAENGNLTAKIQRKSSELERSKQRLQALQ............KVR..PAYLEEFEK....LELELKNLYEQYIIRIRCVDALKSQLISKNRTP---tpt........................................
B4LA63_DROMO/14-271                  ......................KLLGFS.RVLPLQALAT.Hhg.slaNFYIVAEVIQWVSGLLEPGVILA.GNVETEEQRVLLIRVATEFFV..............TKAAIKLNPRKLYAAAAVSCTELQKITSLLIAPTRIEed....veNRDEESEQD.CSLK..........................................................QADIGDK.M...DE.LRRA...RDLS.SDLTQRGAGLFDLLSKELI.................................NKSGRVAQVQ..................RAMEL....VSVERTLK.NAIQASDLKLQSTSAQASRAGENQA----------------ETR--GTP............KLR..PAHMSEFEE....CERELQQLFQRYFLRFHLRDALRNYLKARIK-----rrgt.......................................
A9V562_MONBE/453-723                 ......................RALGYP.RLVSIENFRQ.P......NFPLVAEILVWLLKKFDRSAAIP.LDIDTEADRVIFIKAIAAFMA..............TKAHVRLNTRRLYGADGYAVREMLKVTSLIYSAARQAa.....gaPGVSSGAPP.VSLS..........................................................DFDINTK.L...GD.LKQT...RMLA.GEITSRGANLYELLENEPE.................................LRANRSRVLA..................SGMDI....EQIEQAVR.TSLQQLRMQTEKINGMMNNIAADEANLEGKLEKKRLDLDRNQKRLKSLQ............SVR..PAFMDEYEK....LEGELQTSYEEYVEKYRNLAYLEKELEDFNQREQD-k..........................................
A0A0D9RC92_CHLSB/14-283              ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQE-r..........................................
H0XE88_OTOGA/1-210                   ......................------.----------.-......-----------------------.--------------------A..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSQIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LREMRTEAIG..................RPLEI....NETEKVIR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLTYLEQQLEDHHRMEQE-r..........................................
W4X161_ATTCE/3-63                    ......................RVLGYP.RLISLANFRM.P......NFPLVAEILVWLVKRFDPDVDIF.SDHDTEEQRVTLIRSVAEFM-..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------r..........................................
A0A091D3L3_FUKDA/14-283              ......................RALGYP.RHISMESFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAVAQFMA..............TQAHIKLNTKNLYQADGCAVKELLKITSVLYNAMKTKg......mEGSKIGEED.ISKF..........................................................KFDLSSR.I...AD.LKAA...KQLA.SEITSKGAFLYDLLGKEVE.................................LRKLRTEAIA..................RPLEI....NEIEKVMR.LAIKEILSQVQKTKDLLNNVASDEANLEAKIEKRKLELERSRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYVEKFRNLAYLEQQLEDHHRMEQE-r..........................................
CLUA1_RAT/3-272                      ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDTETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSNVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....VEEELQKQYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
W5NUY0_SHEEP/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQNDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSQLAEED.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAVA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYGIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
F6YBF5_XENTR/14-283                  ......................RALGYP.RLISMENFRS.P......NFPLVAEVLIWLVKRYEPHTDIP.VDVDTEQDRVFFIKAVAQFMA..............TKAHIKLNTRKLYQADGYSVKELLKITTVLYNAMKSKg......mESTQLEDQE.TSTF..........................................................KFNLGSK.I...SD.LKMA...RQLA.SEITSKGATLYDLLGKEAD.................................LREQRTAAIA..................RPLEM....NDTEKVLR.TSIKEVLEQVQKMKDLLSNVASDEQNLEAKIEKRKQELERNRKRLQTLQ............TVR..PAFMDEYEK....IEEELQKHYETYLDKFRNVCYLEQQLEDYHRVEQE-r..........................................
Q57WZ2_TRYB2/14-278                  ......................RLLGYP.NLISMESFRN.P......NVELVADCLFWLIKRYEPSAEIV.YEIEREADRVFFFKQVCEVAL..............AKGRVKLNIKKLYQSDGNAVQEMLILANVLKKAMNTT........--GLEEIDH.ATLQ..........................................................QVIAQRN.V...QD.AKRV...QQLC.SDLTNDGSSLFFLIEEETG.................................QRGERQRVLS..................RATEV....GEFERRLR.EVLKDVTTQVEQLQASIANLSADETTLEQKIESKKTQLERTQKRLKSLN............AVR..PAFMEEYEK....HEGDMHSQFVIYLEQYRNLEYLEHELAKFNAAED--a..........................................
E3NEV7_CAERE/14-306                  ......................RTLRYP.RLMSIENFRN.P......NFQLVAELLEWIVKKFEPDASLDaQMIQTEADRVNFIKNAVLLML..............QNSRIKMNPKKLYQADGHAVQELLPALKILYMAKSED........-PNMDSGPK.WTQV..........................................................KQKLSTK.M...QE.VRIT...RQLS.SQLPETGALLSELISKPEF.................................ISNQHERAAS..................RAIPL....GDAERTLQ.TTVQGIGAEAEQLSNKLNNVASDEAELDEKIERKKREYEQLQKRFAKLQ............SFR..PQYMDEYER....YEERLQKLYEVYVLNFRNLSYLRKVHDDLAKSERQ-rqeelekamrlavekmrleqekkdai.................
G1REX5_NOMLE/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.F...AD.LKAA...RQLA.SEITSKGASLYDLLSMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNQKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDIYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
G0R0U0_ICHMG/14-286                  ......................RGLGYS.RLISMENFRK.P......NFELIADILYWLATRFDPQADIP.EDIQEERQRVEFIKQIAMLFA..............TKTRIKLNTRKLYQADGYAVQEILKVASVLYKAYNSS........--PAEDEEV.Q---..........................................................AFTLPSK.L...SN.VKLH...KQVA.NDITDTAQKLFDLLNKEET.................................LRSHRDKALGfldsi........srnleSNNEQ....AHIEKCVR.QLIEQQDSGIVDMQNYVNNLQKEQKTLEEKIKKVTFELDKSSKQLQILQ............RMK..PAYMEEYTR....LEVELEKLYQIYIEKFRNLDYLEHQLDVYNQIEL--kn.........................................
E2QYA5_CANFA/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVRRYEPQTDIP.SDVETEQDRVFFIKAIAQFLA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSQIGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
E2BJI1_HARSA/14-283                  ......................RVLGYP.RLISIANFRV.P......NFPLVAEILIWLVKRFDPDVDIS.NDHDIEDQRVALIRTVAEFMA..............LKTSVKLNTKKLYQADGYAVKEMLKMTVLLYEAQNSSg......dVEQGRPASN.QTAV..........................................................NFDISDK.I...NE.LKTT...RQLA.SQLTINGATLFDLLGREVE.................................LREIRNTKVA..................RQFDT....SEIEVALK.DVLDSTRKEMDDTRKQIDNVKDTEQNLDARIERRRTELDRNQKRLQTLK............KVR..PAFMEEFEK....LEVELRSLYDDYLQKFRYLAYLEHLYEDAAKAEQE-r..........................................
F4P424_BATDJ/2-267                   ......................RGLGYP.KRISMESFRT.P......NFDLVSDILYWLVKNYDPSIDIS.NDISSEQDRVIFVKSIALFMA..............PKAHIQLNTRKLYTADGYAVKELLKIVNILYEAHTMR........--LDHNSNQ.STIQ..........................................................PLDISNR.I...GK.LKAS...RTLA.SEIIEKGAELYDLLGQEIS.................................LRDRRTDVIS..................RPFEL....AEMEQAVT.AAVNTLRDQMTVTRTGMDNLHSDEINLLAKIEKKKVERDRAEKRLKSLQ............GVR..PAYMDEYEK....IEVELSRLYETYMEKFRNLAFLEQQLDEYNREEQN-k..........................................
X6LS59_RETFI/73-272                  ......................KSLGYH.RLILMDNFRK.P......NFELVADILYWMINRIDPTANIS.DDISTEKKRVFFLKSVASLIF..............KEIEVKLKLKPLYGGDGYAVKELLKVAKILYSASNMD........----NKQQV.PNVD..........................................................EVEQSKC.L...ST.LKQA...QGIG.SIIVQTGARLHELLGQENS.................................IHKHRNKVAHfldel........synleSDDSY....SKIKNAVH.DQINLMCDKINVAKNNIDQLN----------------------------............---..---------....------------------------------------ev.........................................
F6ZII8_CIOIN/14-286                  ......................RGLGYP.RLISVENFRQ.P......NFELVAEILLWLIQRYEPDAHIP.KDIDTEQDRVIFIKSSAQFIA..............TKIHIKLNTKRLYMADGYSVKELLKVASVLHSAIVFL........YQSH---AG.ISRFlilr..................................................skinVLTKASK.I...NE.LKAV...RQLA.SEVTQRGATLYHLLSQEPE.................................LRDARMSALA..................HPLDI....NTIEKGLR.SSIMKVEQNTKSTLQKLDNVAADEANLEAKIEKRKSELDRSKKRLSTLQ............SVR..PAFMDEFER....LEEELKLQYASYLIKFRNMTYLEHQMEDHNRQEQA-r..........................................
E9FS11_DAPPU/2-266                   .....................c-LLGYP.RLISRENFRS.T......NFGLVAEILNWFCQQLDVNSGIN.FLIKTEQERVVFVTSVVKFLN..............TKLQIKLNPKRLYQADNIAVRELLNVANFFYEALQLA........RK---GGEN.NEPS..........................................................LYGFGGQ.A...ED.VREM...RQLA.SEITTKGASIHDFLGQEMR.................................MKNQRDQVLQ..................RTYEL....GQIETALQ.SKMKKMEVEISQKQEAIDSISNNEASLDQKIDKKSLELQRLRKRLETMK............NIR..PPFMDEFEK....LEAELRQCYEDYVSKFRCLSYLDSQWQELEKNEQQ-e..........................................
M7BSK7_CHEMY/170-237                 qcqdrqeaclstpaapltrsrp------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............--R..PAFMDEYEK....IEEELQKQYSSYLEKFRNLAYLEQQLDDHHRLEQE-r..........................................
J3KNW5_HUMAN/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSEIVEED.VNKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....TEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE-r..........................................
C5KSL6_PERM5/109-248                 .................gngfn------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...ED.LRPM...SSLS.SEILEAGAKLHALLQVEAM.................................PDTERAYGVR..................RA---....--------.--RQKAVKFLEGISRNLS-SDRERSNVERQVKKRRAELERTSKRLAGLR............TVR..PAFMDEYEE....LQEFMDQLYEAYVDRFRNLDYLEHELDILNREEEE-r..........................................
B4R445_DROSI/6-182                   .......vrdkrsgqrrggpkd------.----------.-......-----------------------.---------------------..............-------------------------------------........-------QY.RSLN..........................................................PVDIGDK.I...EE.LRKA...RELA.TDLTQRGTTICEMLSKELL.................................HKESLMSQAQ..................RPLEL....LSVERTLK.NAIQASQVRLQSSRAQLEAAKVELNALGSKLQRRRAELERTRQRLEALQ............RIR..PAHMAEFED....CEKELQELFQRFFLRLHVRDALKSQLDLRTKR----atp........................................
W5KID1_ASTMX/14-284                  ......................RALGYP.RLISMENFRA.P......NFPLVAEILIWLVKRYEPQMDIP.SDVDTESDRVFFIKAVAQFMA..............TKAHIKLNLKRMYQADGYAVKEMLKITSVLYNAMKTKq.....naDDDQNLDEG.SSKF..........................................................KFDLGSK.I...AD.LKAA...RQLG.SEITAMGASLYDLLGHEED.................................LRESRTAAIA..................RPLEI....AETERALR.AAIKDVMENVQKTKEQLNNISSDEASLEAKIEKKKQELERNQKRLQTLQ............SVR..PAFMEEYEK....IEEELQKQYETYVEKFRNLSFLEQQLEDHHRVEQE-r..........................................
A0A096M439_POEFO/14-283              ......................RALGYP.RLISMENFVT.P......NFTLVTEILIWLVRRYEPHVDIP.TDVDTESDRIFFIKAVVQFMA..............TKAHIKLNTKHLYQADGYAVKEMLKITSVLYNAMKTKq......mALEDAVEED.SNKF..........................................................KFDLGSR.I...SE.LKAA...RQLA.SEITSRGASLYDLLGKEAE.................................LREMRTAAIA..................RPLEI....NETEKALR.AAIKETLEIVEKIKEMLSNVVSDETSLDAKIEKKKQDLERHQKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYEVFVEKFRNLTYLESQLDEYHRLEQD-r..........................................
E9Q8M4_MOUSE/3-206                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDIETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSNVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDLLAQVQKTKDLLNNVASDEANLEAKI------------------............---..---------....------------------------------------...........................................
G7Y5H0_CLOSI/14-283                  ......................RSLGYN.RIISMENFRT.P......NFPLVAEILAWLVLRYDALADLPsQCLDTEQDRVIFIKSVAHFMA..............TRANIRLNTKKLYQANGYAVKEMMKIATILYTATSTQ.......rRQDAGDTTE.LCVT..........................................................ELFDVAR.R...KQ.LQEG...RSLA.SQLASSGASLHALLGKEVD.................................LRESRDSSIR..................RQLDS....SWVEECVA.AARDALRSQVQKTESSLINIAADEAALDDKIEKKRNELERNRKRLSTLQ............SVR..PAYMEEYEQ....LEEELSALYSFYLTRFRNLAFLENQYEELVK-----agatq......................................
E2C4G9_HARSA/3-272                   ......................RVLGYP.RLISIANFRV.P......NFPLVAEILIWLVKRFDPDVDIS.NDHDIEDQRVALIRTVAEFMA..............LKTSVKLNTKKLYQADGYAVKEMLKMTVLLYEAQNSSg......dVEQGRPASN.QTAV..........................................................NFDISDK.I...NE.LKTT...RQLA.SQLTINGATLFDLLGREVE.................................LREIRNTKVA..................RQFDT....SEIEVALK.DVLDSTRKEMDDTRKQIDNVKDTEQNLDARIERRRTELDRNQKRLQTLK............KVR..PAFMEEFEK....LEVELRSLYDDYLQKFRYLAYLEHLYEDAAKAEQE-r..........................................
D8LND8_ECTSI/2-105                   ......................RALGYP.RSVSMDNFRA.P......NFQLVADVLYWMVKRYDPDIAVS.DNIESENDRVDFLTGVAEAML..............NKAHIKLNAKRLYAADGHAVKELLKLATLLYSASRVE........QN-------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------dtgg.......................................
R1CV11_EMIHU/14-219                  .....................c-TLGYP.RLISIENFRK.P......HFELVADVLIWLCRRYDKKMQIL.DEIRTEGDRIAFLKSAAEQLLarvqcviphwpaaqVRARVKLNLKNLYQANGFAVKELLKVAALLHQAHRGA........--TDDDEQN.ELSF..........................................................DLGPGHA.F...AD.LKTT...RAIS.ADITKYGAALHEALEGHAD.................................AKEAAARALG..................KHHDA....DSMHKQLA.RRSR---------------------------------------------............---..---------....------------------------------------hnvrrnspavpdahlfvqr........................
C1EA98_MICSR/130-323                 ....................ps------.----------.-......-----------------------.---------------------..............---------------HRLAVKELLKIANLLYQATKNA........DEDDATDPE.AATD..........................................................AFELDAG.A...FD.VKLV...RRLA.SEITQRGAAIYDALGDEKR.................................LRGERARAVG..................RDVDL....DEIEAQVQ.EQIASVRDNVQGLERMLGDLRRDEESLESKIEKRRAELERAEKRLSALR............QVR..PAYMDEYDQ....LEAGMDEMYEAYVEKVRNLDYLEWQLREMSADE---daa........................................
I3L1J4_HUMAN/14-75                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.PDVDTEQDRVFFIKAIAQFMI..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------a..........................................
G4YTW6_PHYSP/14-294                  ......................RALGYP.RPISMENFRT.P......NFELVSDLLYWMVKKYDPSSSIA.EEIDTEDDRVEFLTQVATEVL..............AKARIRLNPKRLYAADGFAVKELIKLARVLYEASRIDl.....atQQEPDDDDD.DVSV..........................................................KSLLGSR.V...KD.PKAT...RQLA.SDITQSGAKLYDLLETELD.................................VRDARQQAIRfldal........stnheNSSEQ....KFLERSIQ.EILVNLQDNVELTEHQVVELDAEEKALAAKIKKAQTDLERSEKRLKSLQ............HVR..PAFMDEYEK....LEKELERQYAIYCERFRNLDYLQRELDLHNSREMK-k..........................................
A8QFY5_BRUMA/14-142                  ......................RVLGYP.RLVSMENFRT.P......NFKLIAEILEWLVHRYDAQISIP.LVIETEQERAFFIKSATFYIL..............QKARIKLNPKKLYMADGYAVQEIAVVVRNLYEITRHT........-SDFDQNAT.ISSM..........................................................RNIISSK.I...S-.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------llfnllqiil.................................
G1PXJ3_MYOLU/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIL.SDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mENSKIGEDD.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITYKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
T1JPQ2_TETUR/18-287                  ......................RFLGYP.RLVSIDNFRK.P......NFPLVAEILRWLITRFDSSLEVP.YVIETEQDRVIFVKTCAQLIA..............TKALIKLNTKKIYTADGHAVQEMMKMASLIYQASKQSe......nVDDHNQEDV.ITMS..........................................................ESLIHSK.S...TE.LKKT...RQLA.SKITQKGALLSDLLEKEIE.................................LREKRVQAMN..................RQLAI....PEIEKSLR.DEIKRVEKEIENINYKIEHVASDEANLDVKIEKKQQELERYQKRLATLK............SVR..PAFMDEYEK....LEEEMATLYDVYVTKFRSLVYLDWQLEDSEKTEI--dk.........................................
D8LND8_ECTSI/122-247                 ........eaeapltsqavsgs------.----------.-......-----------------------.---------------------..............-------------------------------------........---------.----..........................................................-------.-...--.----...----.-------------------.................................--------LG..................STRES....ELIESGGR.EILARSRDNIAAMRRQCEDLEADEAELNAKIKKKRNELDRGEKRLKSLQ............AHR..PAFADELDK....LEGELRRYYEVYVDRFRNLDFLEHNLDRFHESEM--ee.........................................
F7GSJ4_CALJA/14-283                  ......................RALGYP.RHVSMENFRK.P......NFELVSEVLLWLVKRYEPQTDIP.LNVDTEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKSKg......mEGSQRVEED.VSKF..........................................................KFDLSSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGMEVE.................................LREMRTEAIA..................RPLEI....NETERVMR.IAIKEVSTQVQKTKDLLNNVASDEANLESKIEKRKLELERNRKRLETLQ............SVR..PCFMDEYEK....VEEELQKQYDIYLEKFQNLTYLEKQLEDYHRMEQE-r..........................................
A7YWT7_BOVIN/14-283                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQNDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSKRAEED.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LRELRTEAVA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYEIYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
E1ZBQ4_CHLVA/26-278                  .................tlgtq------.----------.Q......AFDWVADCTAWLCQRAAPDLAVP.RDYSSEAKRVAFLSALGSQLY..............SRTRIRLHLRRLYRAGGGAVRELRRLAASLAQAAAEL........-----APPA.ATPA..........................................................NLPPLPE.L...-D.RPQL...NELS.QRIGASAAQLVAALAAAPA.................................AAAGARAALA..................ATTDV....DGMEAELR.AALAAARQQKAQLEPAVAALGQEVALLEARVEKRHVELDRLERRLDSLQ............AVK..PAFSAEAEA....LEAELAGLYQQYLHRFRNLEWLEGSLDAYAAERQ--aeae.......................................
G1NB32_MELGA/14-283                  ......................RALGYP.RLVSMENFHG.P......NFALVAELLLWLVRRYEPQSDIP.PDVETEQDRVFFIKAVAQFMA..............TKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEg......mERTDITEED.SSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSKGASLYDLLGKEVE.................................LREARTESIA..................RPLEI....NEAEKMMK.VAIGCVLEEVQKTKDMLSNVALDEANLEAKIEKRKLELERSQKRLQTLQ............SVR..PAFMDEYEK....IEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQE-m..........................................
K3WZQ5_PYTUL/14-268                  ......................RALGYP.RPISVENFRK.P......NFELVSDMLYWMVKKYDPSSSVT.EEIDTEEDRIEFLTQVASEVL..............AKARIRLNPKKLYAADGFAVKELIKLARVLYKASRIDv.....lkLEANDDDDD.DVSV..........................................................KSLLGSR.V...KD.PKAT...RQLS.SDITQSGAKLFDLLEAELD.................................VRDARQHALRfldai........snnseNSSEQ....KYLERSIK.EILQQTQENVEMTERQCEELEAEEKALASKMKKAQTDLERSEKRLKSLQ............HVR..PAFMDEYEK....LEKELERQY---------------------------a..........................................
G3I032_CRIGR/14-238                  ......................RALGYP.RHISMENFRS.P......NFGLVSEVLLWLVKRYEPQTDIP.SDIETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSKVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LREMRTEAIA..................RPLEI....NETEKVMR.IAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..---------....------------------------------------...........................................
T1IRF1_STRMM/14-282                  ......................RGLGFP.RLISMENFRN.P......NFPLVAEILQWLAIRFDPNVDLP.SDIDTEQDRVIFIRSIAQFMA..............MKAHHKLNTKKLYQADGYAVKELLKLITVMYNATKINy.....edEEDNNGDSG.PMMI..........................................................GFDELSK.L...SD.IKST...RQLA.SQITTKGATLYDLLGKEAE.................................LREIRTSVIG..................KQLEL....TEVEQGMK.AAIKT--EEMKKTNEAIENVASDEANLEAKIEKKKSELERNQKRLQTLK............KVR..PAFMDEYEK....LEAELKKHYETYVIRFRCLTYLEQLLDELERVEQE-k..........................................
D8U506_VOLCA/14-279                  ......................KALGYP.RLISMENFRT.P......NFELVADCLYWLLQRYYPGVEIS.DDISTEADRVKFLQSVAQVML..............TKARMKLNIKRLYAADGNAVKELLKLATLLYKATSKA........--GDMDDDS.TEVV..........................................................DVIASLK.G...FN.PKEI...KMSA.SEIIKAGAALYDALGQEPE.................................LREHRARAVA..................GHVDT....DFVERSIR.EAIAMVEDNIHSLENQMEDLERNEKTLDNKIEKKKQELERQEKRLSTLQ............SVR..PAYMDEYER....LQGELNDLYQRYLDKFRNLEFLENELETYYEAEQE-k..........................................
A0A088A5L6_APIME/1-247               ......................------.----------.-......-----AEILVWLVKRFDPDTDIP.SDHTTEEERISLIRAVAEFMA..............LKTNIKLNTKKLYQADGYAVKELLKVATLLYDAQNNS.......nINNVMSDDN.FNTV..........................................................NFDISNK.I...NE.LKST...RQLA.SQLTVTGASLFDLLGREVD.................................LREIRNSKVA..................RQFDI....SEIETALK.SVIENIRKEIEETKKQIESVKDTEQNLDARIERRRAELDRNQKRLQTLK............KVR..PAFMEEFEK....LEVELRILYDDYIQKFRYLAYLEHLYEDSAKTEQE-r..........................................
E0VSQ8_PEDHC/14-282                  .....................q-ELGYP.RLISMENFRM.P......NFPLVAEILSWLVKRFDPDADIP.LEIQTENERIALIKSVAQLLV..............LKANLKLSTKKLYQADGYAVKEMLKITTMLHDSLKTT.......nIKNKETDDL.PEEF..........................................................IVATSIK.L...QE.LKSA...IQLV.GSIVSSGASLYDLLGKEKE.................................IKEIRNNVAF..................RSMEM....PQVEQAVK.ESVQNVSHEIENTRKSIEGLTSSKASLDAKIEKKKSDLDRHTKRLQTLK............KIR..PAFMEEFEK....LEEELKELYNEYVLKYRNLLYLECILEQTEQS----alkk.......................................
A8J6F1_CHLRE/14-279                  ......................KALGYP.RLISMENFRV.P......NFELVADCLYWLVHRYYPGVEIA.DDISTESDRVKFLQSVAQVML..............TKARMKLNIKRLYAADGNAVKELLKLASLLYKATSKA........--GDMDDDA.AEAI..........................................................DVANSLK.G...FN.PKEI...KGLA.AEIIKAGAGLYDALGQEPE.................................LREHRARAVA..................GHVDT....DFVERSIR.EAIAQVEDNIRSLENQMEDLERNEKTLDNKIEKKKQELERQEKRLSTLQ............SVR..PAYMDEYER....LQGELNGLYQSYLDRFRNLEFLENELEAYYQAEQE-k..........................................
T1GH81_MEGSC/35-298                  .........sikvfiysswkfk------.----------.-......CFIIIADILQWLAERLEPGTILP.GGVESEEDRVILIRSATEFFV..............TKCGIKLNPKKLYAASSATSKELQKVTNLLLTTPPDM.......dEKDSDEYSY.GNFH..........................................................QIDIGDK.I...ED.LRRA...RELS.SELTKKGAVLYDLLQKEIS.................................NKEERLAQSN..................RSMEI....AQVEKALR.TAIASSQAKLHSAKAQLESSNVERNSLNAKLQRKRAELERSKQRLDALQ............KIR..PAYLQEFEE....LEDELRELFQQYFQRIQCRDSLKAQLEFRTKT----ttp........................................
A0A044V9T1_ONCVO/6-273               ......................RVLGYP.RLVSMENFRT.P......NFKLVAEILEWIVHRYDAQLSLP.PMIDTEQERAFFIKSATFYIF..............QKARIKLNPKKLYMADGYAVQELAVVVRNLYEIIRRP........TDSNQNATI.SSMR..........................................................NIILSKI.S...EE.LQKC...RQLA.SQIPNHGATLYDLLAKEII.................................AKTERNKALS..................FSLSL....SDSEKAIL.QAIQAMQEELTAVNHNLENVSSDEAALDAKIERRKKEYEQQQKRLAKLQ............SFR..PQCMDEYEK....CEMKLKQLYDIYVLKFRNLTFLQKLQNEFDHAEQQ-r..........................................
T1FVV9_HELRO/14-124                  ......................RAIGYK.RLISLENFKK.P......NFPLLYEILKWLLSYFEPNVFLPnEDIQSCYERVKFVNFVSEFML..............TKANIKINPKKLYEANGYAVKELLKIVQVLHNEVKLN........---------.----..........................................................-------.-...--.----...----.-------------------.................................----------..................-----....--------.-------------------------------------------------............---..---------....------------------------------------easflltpddii...............................
Q29JG2_DROPS/14-287                  ......................KLLGFP.RVFPLQSLAN.Qhg.slaSFHIVSELIQWLAGLMEPGTVLS.GGVETEEQRVLLVRSATEFFV..............TKSAIRLNPRKLYAAAAVTASELQKITRLLIAPSQTE........AEREEEERD.QYRSl........................................................nQVDIGDK.M...EE.LRRA...RELS.SDLTQRGAALYDLLSKELL.................................HKESRQTQAQ..................RPMEL....LSVERTLK.NATQASQLKLQSSRAQLEAARVELNALNSKLQRKRAELERTKQRLEALQ............KIR..PAHMAEFEE....CEKELQMLFQRYFLRLHVRDALRSQLEARTKRT---tp.........................................
A0A096M4D8_POEFO/14-283              ......................RALGYP.RLISMENFVT.P......NFTLVTEILIWLVRRYEPHVDIP.TDVDTESDRIFFIKAVVQFMA..............TKAHIKLNTKHLYQADGYAVKEMLKITSVLYNAMKTKq......mALEDAVEED.SNKF..........................................................KFDLGSR.I...SE.LKAA...RQLA.SEITSRGASLYDLLGKEAE.................................LREMRTAAIA..................RPLEI....NETEKALR.AAIKETLEIVEKIKEMLSNVVSDETSLDAKIEKKKQDLERHQKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYEVFVEKFRNLTYLESQLDEYHRLEQD-r..........................................
D3Z1F2_MOUSE/3-188                   ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDIETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKg......mEGSNVGEED.ISKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITAKGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKDLLAQVQKT------------------------------------............---..---------....------------------------------------...........................................
L9LED6_TUPCH/11-280                  ......................RALGYP.RHISMENFRT.P......NFGLVSEVLLWLVKRYEPQTDIP.SDVETEQDRVFFIKAIAQFMA..............TKAHIKLNTKKLYQADGHAVKELLKITSVLYHAMKTKg......mQGSDIGEED.VSKF..........................................................KFDLGSK.I...AD.LKAA...RQLA.SEITSRGASLYDLLGKEVE.................................LRELRTEAIA..................RPLEI....NETEKVMR.IAIKEILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQ............SVR..PAFMDEYEK....IEEELQKQYDVYLEKFRNLAYLEQQLEDHHRMEQE-r..........................................
#=GC seq_cons                        ......................RsLGYP.RhIShEsFRs.P......NF.LVuElLhWLlpRa-Ppssls.s-l-TEp-RVhFl+ulsphhs..............sKu+IKLNsK+LYtADGaAV+ELLKlsslLYsAhpsp..........sp.sppt..sth..........................................................phslus+.l...t-.LKts...RpLu.S-lTppGAsLaDLLucEhc.................................lRchRppulu..................+sh-l....sphE+sh+..slpph.tplpphpp.lsslsuDEssL-uKI-+++.ELERspKRLpoLp............sVR..PAaM-EYE+....hEpELpp.YphYlp+aRNLsaLEppL-php+hEp..c..........................................
//
DBGET integrated database retrieval system