#=GF ID CobW_C
#=GF AC PF07683.9
#=GF DE Cobalamin synthesis protein cobW C-terminal domain
#=GF AU Bateman A
#=GF SE Pfam-B_1247 (release 5.4)
#=GF GA 20.60 20.60;
#=GF TC 20.60 20.60;
#=GF NC 20.50 20.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF WK Cobalamin_biosynthesis
#=GF RN [1]
#=GF RM 1655697
#=GF RT Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair
#=GF RT Pseudomonas denitrificans DNA fragment containing five cob genes
#=GF RT and identification of structural genes encoding Cob(I)alamin
#=GF RT adenosyltransferase, cobyric acid synthase, and bifunctional cob
#=GF RA Crouzet J, Levy-Schil S, Cameron B, Cauchois L, Rigault S,
#=GF RA Rouyez MC, Blanche F, Debussche L, Thibaut D;
#=GF RL J Bacteriol 1991;173:6074-6087.
#=GF RN [2]
#=GF RM 19822009
#=GF RT A subset of the diverse COG0523 family of putative metal
#=GF RT chaperones is linked to zinc homeostasis in all kingdoms of
#=GF RT life.
#=GF RA Haas CE, Rodionov DA, Kropat J, Malasarn D, Merchant SS, de
#=GF RA Crecy-Lagard V;
#=GF RL BMC Genomics. 2009;10:470.
#=GF DR INTERPRO; IPR011629;
#=GF DR SCOP; 1nij; fa;
#=GF CC This is a large and diverse family of putative metal chaperones
#=GF CC that can be separated into up to 15 subgroups. In addition to
#=GF CC known roles in cobalamin biosynthesis [1] and the activation of
#=GF CC the Fe-type nitrile hydratase, this family is also known to be
#=GF CC involved in the response to zinc limitation. The CobW subgroup
#=GF CC involved in cobalamin synthesis represents only a small
#=GF CC sub-fraction of the family [2].
#=GF SQ 5707
#=GS I0YR23_9CHLO/253-374 AC I0YR23.1
#=GS G4Z3P4_PHYSP/267-378 AC G4Z3P4.1
#=GS A3N9F1_BURP6/259-350 AC A3N9F1.1
#=GS E2XDD8_SHIDY/224-317 AC E2XDD8.1
#=GS G4NQT7_BACPN/259-374 AC G4NQT7.1
#=GS A3I6R1_9BACI/258-373 AC A3I6R1.1
#=GS Q880K5_PSESM/261-352 AC Q880K5.1
#=GS G8SV14_BRUCA/259-375 AC G8SV14.1
#=GS H9UUC1_ECOLX/177-260 AC H9UUC1.1
#=GS B9QU55_9RHOB/278-367 AC B9QU55.1
#=GS E0P6X4_STAAU/260-375 AC E0P6X4.1
#=GS D2VJR8_NAEGR/296-417 AC D2VJR8.1
#=GS G6C580_9FUSO/214-284 AC G6C580.1
#=GS A6DWJ8_9RHOB/270-360 AC A6DWJ8.1
#=GS A7JLS5_FRANO/258-376 AC A7JLS5.1
#=GS D7YPB3_ECOLX/224-317 AC D7YPB3.1
#=GS C0G358_9RHIZ/513-608 AC C0G358.1
#=GS G1YJ92_ECOLX/224-317 AC G1YJ92.1
#=GS H6S545_MYCTU/235-351 AC H6S545.1
#=GS D6T6A6_STAAU/220-306 AC D6T6A6.1
#=GS G2M978_HELPX/220-310 AC G2M978.1
#=GS G7DRI7_BRAJP/253-343 AC G7DRI7.1
#=GS E7YVG5_SALMO/240-323 AC E7YVG5.1
#=GS D1P9P3_9BACT/361-479 AC D1P9P3.1
#=GS B3H8V0_ECOLX/240-323 AC B3H8V0.1
#=GS B9BPF4_9BURK/225-318 AC B9BPF4.1
#=GS F9JWB3_STAAU/260-375 AC F9JWB3.1
#=GS F7VCJ9_9PROT/234-328 AC F7VCJ9.1
#=GS B9S1U2_RICCO/318-412 AC B9S1U2.1
#=GS H1T0J1_STAAU/212-294 AC H1T0J1.1
#=GS B0CVH4_LACBS/288-385 AC B0CVH4.1
#=GS E3EHL8_PAEPS/259-374 AC E3EHL8.1
#=GS D3R2N2_CLOB3/231-316 AC D3R2N2.1
#=GS A5UXW8_ROSS1/247-339 AC A5UXW8.1
#=GS B0CHA2_BRUSI/256-349 AC B0CHA2.1
#=GS D2FR75_STAAU/212-294 AC D2FR75.1
#=GS I1J1D3_BRADI/315-409 AC I1J1D3.1
#=GS C0DWT6_EIKCO/221-307 AC C0DWT6.1
#=GS G2BYH5_ECOLX/224-317 AC G2BYH5.1
#=GS C8ZFQ6_YEAS8/337-428 AC C8ZFQ6.1
#=GS B3Q556_RHIE6/260-375 AC B3Q556.1
#=GS E7Z4B6_SALMO/224-317 AC E7Z4B6.1
#=GS A2C4Q3_PROM1/366-459 AC A2C4Q3.1
#=GS G4G595_9EURY/256-371 AC G4G595.1
#=GS E7ID08_ECOLX/240-323 AC E7ID08.1
#=GS C2QAR9_BACCE/241-326 AC C2QAR9.1
#=GS C6CL21_DICZE/240-323 AC C6CL21.1
#=GS C4XCW8_KLEPN/2-114 AC C4XCW8.1
#=GS B0M9D0_9FIRM/261-347 AC B0M9D0.1
#=GS A5IQP1_STAA9/220-306 AC A5IQP1.1
#=GS G8QFX7_AZOSU/245-343 AC G8QFX7.1
#=GS C0C4K5_9CLOT/256-343 AC C0C4K5.1
#=GS H7TKI8_CAMCO/216-308 AC H7TKI8.1
#=GS Q15Z57_PSEA6/271-388 AC Q15Z57.1
#=GS G8NFK4_BRUSS/256-349 AC G8NFK4.1
#=GS F8F8M6_PAEMK/262-347 AC F8F8M6.1
#=GS B2GK15_KOCRD/227-317 AC B2GK15.1
#=GS C6TQH1_BURPE/263-357 AC C6TQH1.1
#=GS C8L1A0_STAAU/212-294 AC C8L1A0.1
#=GS F1YVS2_9PROT/255-349 AC F1YVS2.1
#=GS Q63U47_BURPS/259-350 AC Q63U47.1
#=GS D3ETD1_STAA4/212-294 AC D3ETD1.1
#=GS D2GM65_STAAU/212-294 AC D2GM65.1
#=GS E9TU15_ECOLX/224-317 AC E9TU15.1
#=GS F0PJP5_BACT0/218-303 AC F0PJP5.1
#=GS G0B9B8_SERSA/239-322 AC G0B9B8.1
#=GS G9QBQ8_9BACI/256-371 AC G9QBQ8.1
#=GS C9WZ72_NEIM8/221-307 AC C9WZ72.1
#=GS H7VQD6_CAMCO/216-308 AC H7VQD6.1
#=GS Q3AV30_SYNS9/252-340 AC Q3AV30.1
#=GS B1R847_CLOPF/223-308 AC B1R847.1
#=GS G2LJE6_CHLTF/359-452 AC G2LJE6.1
#=GS E5AEG7_LEPMJ/394-506 AC E5AEG7.1
#=GS C3HGQ9_BACTU/256-371 AC C3HGQ9.1
#=GS H5VYK9_SALEN/240-323 AC H5VYK9.1
#=GS A8IHD7_CHLRE/833-962 AC A8IHD7.1
#=GS F3ZIN6_9ACTO/234-325 AC F3ZIN6.1
#=GS B4W5J6_9CAUL/260-376 AC B4W5J6.1
#=GS A3IX61_9CHRO/254-346 AC A3IX61.1
#=GS E7V8N7_SALMO/224-317 AC E7V8N7.1
#=GS I0BGN3_9BACL/239-333 AC I0BGN3.1
#=GS A8G599_PROM2/355-448 AC A8G599.1
#=GS A0LPD0_SYNFM/533-619 AC A0LPD0.1
#=GS E8W525_STRFA/234-325 AC E8W525.1
#=GS E7WSE0_SALMO/224-317 AC E7WSE0.1
#=GS C2PDS5_BACCE/241-326 AC C2PDS5.1
#=GS D3QJW5_ECOCB/240-323 AC D3QJW5.1
#=GS C0B571_9FIRM/235-311 AC C0B571.1
#=GS F3EW53_9PSED/229-322 AC F3EW53.1
#=GS E5UC79_ALCXX/239-333 AC E5UC79.1
#=GS A9IZR6_BART1/236-331 AC A9IZR6.1
#=GS H5F1B5_ECOLX/240-323 AC H5F1B5.1
#=GS H4IKH2_ECOLX/224-317 AC H4IKH2.1
#=GS D8MZQ9_RALSL/274-362 AC D8MZQ9.1
#=GS Q1MEG0_RHIL3/259-375 AC Q1MEG0.1
#=GS H8E7C4_9MICO/240-328 AC H8E7C4.1
#=GS Q2VNT1_9BACT/236-330 AC Q2VNT1.1
#=GS A9ITZ5_BORPD/243-337 AC A9ITZ5.1
#=GS E1V9T0_HALED/263-380 AC E1V9T0.1
#=GS E8UEJ5_TAYEM/224-316 AC E8UEJ5.1
#=GS C8LQE4_STAAU/260-375 AC C8LQE4.1
#=GS H4SLM3_ECOLX/224-317 AC H4SLM3.1
#=GS A5L576_9GAMM/257-374 AC A5L576.1
#=GS D1EGB0_NEIGO/221-307 AC D1EGB0.1
#=GS B7MXI8_ECO81/240-323 AC B7MXI8.1
#=GS A8JDZ5_CHLRE/229-328 AC A8JDZ5.1
#=GS A6BFT6_9FIRM/290-377 AC A6BFT6.1
#=GS H5JSG9_ECOLX/224-317 AC H5JSG9.1
#=GS Q62G68_BURMA/274-395 AC Q62G68.1
#=GS Q1NG17_9SPHN/262-378 AC Q1NG17.1
#=GS Q99WF2_STAAM/260-375 AC Q99WF2.1
#=GS A8PXL5_MALGO/521-631 AC A8PXL5.1
#=GS Q727Q0_DESVH/257-343 AC Q727Q0.1
#=GS F2IXD8_POLGS/270-359 AC F2IXD8.1
#=GS H0Y857_HUMAN/56-159 AC H0Y857.1
#=GS E2SWN7_9RALS/260-384 AC E2SWN7.1
#=GS A9MK39_SALAR/249-332 AC A9MK39.1
#=GS C4RH35_9ACTO/339-454 AC C4RH35.1
#=GS A6VV96_MARMS/259-376 AC A6VV96.1
#=GS A1WRJ7_VEREI/261-355 AC A1WRJ7.1
#=GS I0KIY5_STEMA/263-416 AC I0KIY5.1
#=GS E3A4U0_PSEAI/235-318 AC E3A4U0.1
#=GS B0KR85_PSEPG/238-321 AC B0KR85.1
#=GS B1MJI0_MYCA9/258-349 AC B1MJI0.1
#=GS H3ZTH7_STAAU/220-306 AC H3ZTH7.1
#=GS F9L0M6_STAAU/220-306 AC F9L0M6.1
#=GS G5GWI3_FUSNP/225-294 AC G5GWI3.1
#=GS B7JJN8_BACC0/218-303 AC B7JJN8.1
#=GS B2TCN1_BURPP/227-321 AC B2TCN1.1
#=GS G6GQD6_9CHRO/252-340 AC G6GQD6.1
#=GS C2XAR9_BACCE/224-318 AC C2XAR9.1
#=GS Q0BAY2_BURCM/293-387 AC Q0BAY2.1
#=GS E8MA38_9VIBR/253-372 AC E8MA38.1
#=GS H3QPC2_BRUAO/285-378 AC H3QPC2.1
#=GS H1HDR6_FUSNU/224-294 AC H1HDR6.1
#=GS G2WL85_YEASK/336-428 AC G2WL85.1
#=GS E9YQ06_ECOLX/240-323 AC E9YQ06.1
#=GS H4GAQ0_STAAU/260-375 AC H4GAQ0.1
#=GS C0EZQ6_9FIRM/234-312 AC C0EZQ6.1
#=GS B5Y598_PHATC/247-347 AC B5Y598.1
#=GS F3BDF8_9FIRM/219-299 AC F3BDF8.1
#=GS F3FIB7_PSESX/229-322 AC F3FIB7.1
#=GS H3WIF7_STAEP/260-375 AC H3WIF7.1
#=GS H8M8M0_SALTM/274-357 AC H8M8M0.1
#=GS F0E8L2_9PSED/64-158 AC F0E8L2.1
#=GS E9TA90_ECOLX/240-323 AC E9TA90.1
#=GS F5KGL1_PSEAI/235-318 AC F5KGL1.1
#=GS F0GB62_9BURK/1-93 AC F0GB62.1
#=GS E2RB95_CANFA/275-378 AC E2RB95.1
#=GS C5NEJ1_BURML/274-395 AC C5NEJ1.1
#=GS H8DGX1_ECOLX/224-317 AC H8DGX1.1
#=GS H8GK16_METAL/264-380 AC H8GK16.1
#=GS E3Q8M9_COLGM/415-531 AC E3Q8M9.1
#=GS A8YMW0_MICAE/264-352 AC A8YMW0.1
#=GS F0A5C3_NEIME/221-307 AC F0A5C3.1
#=GS D3QES6_STALH/193-279 AC D3QES6.1
#=GS F3GZZ4_PSESX/256-373 AC F3GZZ4.1
#=GS G8PIJ5_PSEUV/247-342 AC G8PIJ5.1
#=GS B5HYB3_9ACTO/250-366 AC B5HYB3.2
#=GS E7MXY2_STAAU/260-375 AC E7MXY2.1
#=GS Q1CG53_YERPN/239-322 AC Q1CG53.1
#=GS F5W3J4_STAAU/212-294 AC F5W3J4.1
#=GS F0YCQ7_AURAN/248-344 AC F0YCQ7.1
#=GS C2XA37_BACCE/256-371 AC C2XA37.1
#=GS H1FBV0_ECOLX/252-370 AC H1FBV0.1
#=GS H4A7S8_STAAU/212-294 AC H4A7S8.1
#=GS B7JIS9_BACC0/256-371 AC B7JIS9.1
#=GS B1VRF9_STRGG/240-356 AC B1VRF9.1
#=GS Q5WIZ8_BACSK/226-320 AC Q5WIZ8.1
#=GS H0J524_9GAMM/267-384 AC H0J524.1
#=GS Q3M243_ANAVT/115-210 AC Q3M243.1
#=GS D0ZAB8_EDWTE/239-322 AC D0ZAB8.1
#=GS C2PE16_BACCE/224-318 AC C2PE16.1
#=GS H1M4X8_9BACT/217-302 AC H1M4X8.1
#=GS D5D6X0_ECOKI/240-323 AC D5D6X0.1
#=GS F3DH95_9PSED/230-324 AC F3DH95.1
#=GS C3GH34_BACTU/256-371 AC C3GH34.1
#=GS B5P2X4_SALET/249-332 AC B5P2X4.1
#=GS C5TIQ9_NEIFL/221-307 AC C5TIQ9.1
#=GS H0QUR7_9ACTO/265-381 AC H0QUR7.1
#=GS A9GCA0_9RHOB/268-359 AC A9GCA0.1
#=GS H6LG59_ACEWD/204-283 AC H6LG59.1
#=GS D3A082_NEIMU/221-307 AC D3A082.1
#=GS B9DL22_STACT/260-375 AC B9DL22.1
#=GS G5WMW1_ECOLX/224-317 AC G5WMW1.1
#=GS B0CCJ8_ACAM1/227-321 AC B0CCJ8.1
#=GS Q5RIB0_HUMAN/255-358 AC Q5RIB0.1
#=GS H4ETE6_STAAU/212-294 AC H4ETE6.1
#=GS F8VI93_SALBC/224-317 AC F8VI93.1
#=GS F2J5R2_POLGS/258-374 AC F2J5R2.1
#=GS I0JAH2_STAAU/260-375 AC I0JAH2.1
#=GS F9DE46_9BACT/376-492 AC F9DE46.1
#=GS F5XSE8_MICPN/256-366 AC F5XSE8.1
#=GS E7IXP7_ECOLX/224-317 AC E7IXP7.1
#=GS H7UQC5_CAMCO/216-308 AC H7UQC5.1
#=GS F2FLL0_SALDU/224-317 AC F2FLL0.1
#=GS B9E3Z3_CLOK1/237-324 AC B9E3Z3.1
#=GS B2SC99_BRUA1/259-375 AC B2SC99.1
#=GS A5GUH2_SYNR3/260-348 AC A5GUH2.1
#=GS I1DFT6_9VIBR/252-372 AC I1DFT6.1
#=GS C1EC16_MICSR/293-428 AC C1EC16.1
#=GS C2M017_STAHO/219-305 AC C2M017.1
#=GS B0UH23_METS4/253-344 AC B0UH23.1
#=GS A1KES7_MYCBP/235-351 AC A1KES7.1
#=GS C5QAD3_STAEP/260-375 AC C5QAD3.1
#=GS B1UNM6_BACAN/218-303 AC B1UNM6.1
#=GS D2HD78_AILME/274-377 AC D2HD78.1
#=GS C6BI50_RALP1/260-384 AC C6BI50.1
#=GS H3VWG8_STAEP/220-306 AC H3VWG8.1
#=GS A9W3M1_METEP/233-327 AC A9W3M1.1
#=GS A0K2U1_BURCH/276-396 AC A0K2U1.1
#=GS D3EPD4_UCYNA/230-318 AC D3EPD4.1
#=GS F0IZP4_ACIMA/527-615 AC F0IZP4.1
#=GS B1LYP5_METRJ/262-377 AC B1LYP5.1
#=GS C8W437_DESAS/241-329 AC C8W437.1
#=GS C5A836_BURGB/276-397 AC C5A836.1
#=GS E3PR64_CLOSD/219-307 AC E3PR64.1
#=GS Q7W213_BORPA/273-367 AC Q7W213.1
#=GS Q4LA72_STAHJ/260-375 AC Q4LA72.1
#=GS D8NAD5_RALSL/266-359 AC D8NAD5.1
#=GS D1EKC5_9RHIZ/285-378 AC D1EKC5.1
#=GS A1WGM1_VEREI/238-332 AC A1WGM1.1
#=GS F7D4T8_HORSE/274-377 AC F7D4T8.1
#=GS H5H0Z8_ECOLX/224-317 AC H5H0Z8.1
#=GS A7IGM8_XANP2/271-366 AC A7IGM8.1
#=GS A9WWY6_BRUSI/259-375 AC A9WWY6.1
#=GS A8J7S8_CHLRE/3-103 AC A8J7S8.1
#=GS H6SIJ4_RHOPH/279-374 AC H6SIJ4.1
#=GS D4K0R0_9FIRM/234-311 AC D4K0R0.1
#=GS Q31AJ2_PROM9/355-448 AC Q31AJ2.1
#=GS H3U756_STAAU/220-306 AC H3U756.1
#=GS G5TSM1_ECOLX/224-317 AC G5TSM1.1
#=GS H1RVC3_COMTE/264-350 AC H1RVC3.1
#=GS Q8Y3D3_RALSO/268-361 AC Q8Y3D3.1
#=GS H3VAS3_STAEP/212-292 AC H3VAS3.1
#=GS A1K2L7_AZOSB/321-418 AC A1K2L7.1
#=GS H3LQY2_KLEOX/240-323 AC H3LQY2.1
#=GS D6JLD5_NEIGO/221-307 AC D6JLD5.1
#=GS E7U512_ECOLX/240-323 AC E7U512.1
#=GS A7Z178_BACA2/259-375 AC A7Z178.1
#=GS H3T057_PSEAE/259-349 AC H3T057.1
#=GS H8LCB4_ENTFU/233-323 AC H8LCB4.1
#=GS D6BB28_9ACTO/236-327 AC D6BB28.1
#=GS E3HKL4_ACHXA/239-331 AC E3HKL4.1
#=GS D4RMC7_ENTFC/259-375 AC D4RMC7.1
#=GS H1CA90_9FIRM/237-323 AC H1CA90.1
#=GS D7G996_ECTSI/492-598 AC D7G996.1
#=GS C5AUP4_METEA/262-377 AC C5AUP4.1
#=GS H3YKE1_STAAU/260-375 AC H3YKE1.1
#=GS B9B676_9BURK/225-320 AC B9B676.1
#=GS H0JLB5_9NOCA/230-321 AC H0JLB5.1
#=GS H4ZG07_ECOLX/240-323 AC H4ZG07.1
#=GS C3EJ40_BACTK/256-371 AC C3EJ40.1
#=GS E3E352_BACA1/256-371 AC E3E352.1
#=GS D2R1V1_PIRSD/260-376 AC D2R1V1.1
#=GS G8W184_KLEPN/241-323 AC G8W184.1
#=GS D0J6D7_COMT2/261-347 AC D0J6D7.1
#=GS Q0BFF9_BURCM/265-355 AC Q0BFF9.1
#=GS E4J0P9_ENTFC/233-323 AC E4J0P9.1
#=GS C3BJA8_9BACI/222-307 AC C3BJA8.1
#=GS E6A8D2_ECOLX/224-317 AC E6A8D2.1
#=GS G0RI86_HYPJQ/390-497 AC G0RI86.1
#=GS D8G114_9CYAN/281-369 AC D8G114.1
#=GS D2VL03_NAEGR/11-95 AC D2VL03.1
#=GS C7LJN9_BRUMC/259-375 AC C7LJN9.1
#=GS A3K4S0_9RHOB/257-351 AC A3K4S0.1
#=GS B9JGD0_AGRRK/256-349 AC B9JGD0.1
#=GS E5TDF3_STAAU/220-306 AC E5TDF3.1
#=GS C6DB97_PECCP/233-327 AC C6DB97.1
#=GS H4BMX1_STAAU/220-306 AC H4BMX1.1
#=GS E6YT15_9RHIZ/231-326 AC E6YT15.1
#=GS C4R878_PICPG/284-375 AC C4R878.1
#=GS H4VQ83_ECOLX/224-317 AC H4VQ83.1
#=GS D6IJJ5_ECOLX/224-317 AC D6IJJ5.1
#=GS G8MMI5_9BURK/249-342 AC G8MMI5.1
#=GS H7SV38_CAMCO/216-308 AC H7SV38.1
#=GS G3B1S3_CANTC/301-395 AC G3B1S3.1
#=GS G4KYL6_OSCVS/255-339 AC G4KYL6.1
#=GS A3K453_9RHOB/253-346 AC A3K453.1
#=GS C7C8H2_METED/262-377 AC C7C8H2.1
#=GS C1B1M9_RHOOB/232-323 AC C1B1M9.1
#=GS D3ET42_STAA4/260-375 AC D3ET42.1
#=GS E7WE76_SALMO/249-332 AC E7WE76.1
#=GS E8FFG2_SALMO/240-323 AC E8FFG2.1
#=GS H4NYN3_ECOLX/224-317 AC H4NYN3.1
#=GS B2TF64_BURPP/218-307 AC B2TF64.1
#=GS H0LYK5_SALMO/224-317 AC H0LYK5.1
#=GS E8IAB9_ECOLX/240-323 AC E8IAB9.1
#=GS G5GJC3_9FIRM/223-308 AC G5GJC3.1
#=GS A9DPY9_9FLAO/260-379 AC A9DPY9.1
#=GS G9AY55_PANAN/266-381 AC G9AY55.1
#=GS Q3JXA0_BURP1/263-357 AC Q3JXA0.1
#=GS C5EXN0_9HELI/216-308 AC C5EXN0.1
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I1DFT6_9VIBR/252-372 ..................................................it--AKVIK.D.DRPFHP....MRLW.E.ACHQ...............hLT......................................KG...VFRSK.GFF..W.FP.................TR...D....D..vSL...LWS........QANG.N.VGLEV....T....G..F......WRASViedesqnftieh..................................kqrlqdkidsvesRFGDRRCRLTVI.........GQ....ENE....VDN....FIDALQAC-f...............................................................................
C1EC16_MICSR/293-428 ..................................................vv--TACCA.E.RGALNR....VAFV.E.WIQSvh............aaAG......................................GG...LARCK.GDV..E.LA.................GE...G....G..rRL...VVD........GVGG.A.LTLRE....E....A..G......REERSrgaagdgtdqrdgtegwg......................gdgpkaplcgdascqisehRHGDRPSRVFFA.........GK....SMK....VSK....LRAGFRAC-f...............................................................................
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C5QAD3_STAEP/260-375 ....................................................ITSFAYT.R.RLPFHA....KRFH.Q.WLEQ................MP......................................EN...IVRTK.GIV..W.LA.................QY...N....D..vAC...LLS........QAGS.S.CNIHP....V....T..Y......WVATMsesqqqaile......................................arqdvvedwdiEYGDRQTQFVII.........GT....DLD....QEK....ISRELDACL................................................................................
B1UNM6_BACAN/218-303 ....................................................IQTMTYQ.F.TKSIDQ....DKLY.E.WLSN................LP......................................DS...IYRVK.GFV..K.FH.................GD...K....Y...PH...LFQ........YSFG.V.PTLL-....-....-..-......----E...........................................................QDFGFPTNLVVI.........GE....GLD....KKQ....LAEGLEK--ve..............................................................................
D2HD78_AILME/274-377 ....................................................IITVTFE.V.RGNAKE....ESLN.V.FIQN...............lLWeknvr...........................nkdndcME...VIRLK.GLV..S.IK.................DK...S....K...QV...IVQ........GVHE.L.YDLEE....T....P..L......SWND-...........................................................-DTERTNRLVLI.........GR....NLD....KEI....LKQLFIA--tv..............................................................................
C6BI50_RALP1/260-384 ....................................................IRSFVYR.R.RVAFHP....QRLW.D.LMHTew............lrEH......................................GR...VLRSK.GYF..W.LA.................SR...M....D..tAG...SWG........QAGG.V.MRHGG....A....G..A......WWAAVdeaewpdeeeara.................................diqdkmhdngapaQWGDRRQELVFI.........GT....DLD....EAA....LIAQLDTCL................................................................................
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A0K2U1_BURCH/276-396 ...................................................i-GNFVYR.A.RRPFHP....ARLW.A.LLHQ................EW......................................PG...VLRSK.GFF..W.LA.................TR...N....D..iAG...SLS........QAGG.V.CRHGP....A....G..L......WWAAQdraewpdddella.................................eirtewlgdlddrTVGDRRQELVLI.........GI....ALD....ADA....WRAKLDACL................................................................................
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F0IZP4_ACIMA/527-615 .........................................vswhgtlgplc-------.-.----DA....EAIG.R.VIEAaa............rgTF......................................GP...VARLK.GLA..R.VG.................RG...-....-...WI...QFD........VAGH.H.ASMAA....F....A..A......-----...........................................................-AEGEAPRVVAI.........GR....DLD....ETG....LAAAFAGC-e...............................................................................
B1LYP5_METRJ/262-377 ....................................................IASFVYR.A.RRPFDP....ERFN.A.FVNA................TW......................................PG...LIRAK.GHF..W.LA.................TR...P....D..wVG...EFS........LAGA.V.ARVSA....M....G..F......WWSAVprrrwpeape......................................frtrlqdvwseVWGDRRQELVFI.........GA....GMD....AAA....LTAALDACL................................................................................
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C5A836_BURGB/276-397 ....................................................IGSFVYR.A.RRPFHP....QRFW.A.LLHE................EW......................................RG...VLRSK.GFF..W.LA.................TR...H....D..iGG...SLS........QAGG.V.CRHGP....A....G..L......WWAAQdraewpeddpall................................deiaadwhgepgdtTVGDRRQELVLI.........GI....GLD....ADA....WRAKFDACL................................................................................
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Q7W213_BORPA/273-367 ....................................................IGAFVFR.S.NKPFDP....ARLE.E.FLGGvv............qvYG......................................PD...LLRYK.GIL..Y.MK.................GI...N....R...RM...LFQ........GVHM.M.MGAEP....G....K..A......WTAA-...........................................................--EKPSTKMVFI.........GR....KLP....QEI....FTRGLEQCL................................................................................
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H5H0Z8_ECOLX/224-317 ....................................................ISSIVVE.L.DYPVDI....SEVS.R.VMENll............leSA......................................DK...LLRYK.GML..W.ID.................GE...P....N...RL...LFQ........GVQR.L.YSAD-....W....D..R......PWGD-...........................................................--ETPHSTMVFI.........GI....QLP....EDE....IRAAFAG--lk..............................................................................
A7IGM8_XANP2/271-366 ....................................................IRAFTLA.T.DAAIPA....ATLD.L.FLELlr............atHG......................................GN...VLRMK.GIV..K.VA.................EE...P....D..aPI...VIH........AVQH.V.MHPPA....R....L..P......AWPD-...........................................................--EDHRTRLVMI.........VR....DLD....PKV....IARLFNAFL................................................................................
A9WWY6_BRUSI/259-375 ....................................................VRSFVYR.A.RKPFDP....ARFQ.A.FIDQ................NW......................................PG...VVRSK.GFF..W.LA.................TR...P....D..fVG...EIS........QAGA.L.VRTSK....R....G..R......WWSAVpkhywpaepe......................................wqramqpyfheVWGDRRQEIVFI.........GI...dPMR....QEA....IIAELDKCL................................................................................
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H6SIJ4_RHOPH/279-374 ....................................................IGAFVLT.Y.DKPLPW....DAFV.M.AMDMli............asKG......................................EG...LLRVK.GIL..D.IQ.................GQ...D....K...PI...AVH........GVQH.I.FHPPL....A....L..P......AWPE-...........................................................-GEPKRSRLVFI.........TR....DLT....RDS....VAGLLAA--tf..............................................................................
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Q31AJ2_PROM9/355-448 ...................................................v-GSIAIE.R.FGDVDP....EKLN.T.WMGRll............seKG......................................VD...IFRTK.GYI..S.YS.................GN...P....R...RI...VFQ........GVHM.L.FTAQ-....P....D..K......EWGN-...........................................................--EPRRNQLVFI.........GR....NLN....EKE....MQEGFDKCL................................................................................
H3U756_STAAU/220-306 ....................................................IKSMTYT.F.TGPIDR....QLFY.Q.FIMK................LS......................................ES...VLRLK.GYV..S.FR.................DQ...P....N..aIY...EFQ........YAYG.L.PDYG-....-....-..-......----I...........................................................IGMQLPLTIVII.........GE....TLD....TNH....IRNQLDM--lq..............................................................................
G5TSM1_ECOLX/224-317 ....................................................ISSIVVE.L.DYPVDI....SEVS.R.VMENll............leSA......................................DK...LLRYK.GML..W.ID.................GE...P....N...RL...LFQ........GVQR.L.YSAD-....W....D..R......PWGD-...........................................................--EKPHSTMVFI.........GI....QLP....EEE....IRAAFAG--lr..............................................................................
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Q8Y3D3_RALSO/268-361 ....................................................IASFVFR.S.ERPFNY....TKLE.E.FLSGvl............nvYG......................................EK...LLRYK.GVL..Y.ME.................GV...D....R...KV...VFQ........GVHQ.L.MGSD-....V....G..G......KWDG-...........................................................--ETPGNRMVFI.........GV....DLP....RDT....ILKGLENCL................................................................................
H3VAS3_STAEP/212-292 ............................................inhqfien-------.-.PRLQTK....EEMI.S.ALDN................LP......................................QD...VYRVK.GFV..R.FS.................NQ...Q....H...VY...LVQ........YAQG.N.IELSP....I....Q..L......-----...........................................................-KADVPLYLIVI.........GK....HLK....QIQ....L--------d...............................................................................
A1K2L7_AZOSB/321-418 ....................................................IASHVLV.F.DAPLTW....YGFS.D.ALGVil............qaYG......................................DR...ILRVK.GLM..N.IA.................GD...P....L...PR...VVQ........CVQH.V.AYPPA....S....L..P......AWPTR..........................................................pPYDDRRSRLVFI.........VR....DLP....RSE....LEQIF----fgv.............................................................................
H3LQY2_KLEOX/240-323 ...................................................a-CGWIFD.A.ETVFDT....VALL.E.WARL................--......................................AP...VGRVK.GVM..R.IA.................EG...-....-...LV...RIN........RQQL.D.LHIE-....-....T..Q......N----...........................................................-VAPPDSRIELI.........AD...tETD....WNA....LQASLLK--ir..............................................................................
D6JLD5_NEIGO/221-307 ...................................................s-QGFTFP.A.GRDFNG....EKLT.N.FFNDl.............pkMT......................................EG...LVRAK.GVF..Q.VL.................GT...-....-...WV...WLN........WVDG.Q.WGAN-....-....-..-......----Q...........................................................VSWRRDSRFELI.........AK....SFD....ADL....IEQKLKDAL................................................................................
E7U512_ECOLX/240-323 ...................................................a-CGWIFD.A.DTVFDT....IGIL.E.WARL................--......................................AP...VERVK.GVL..R.IP.................EG...-....-...LV...RIN........RQGD.D.LHIE-....-....T..Q......-----...........................................................NVAPPDSRIELI.........SS...sEAD....WNA....LQSALLK--lr..............................................................................
A7Z178_BACA2/259-375 ....................................................ITSFVYS.R.RLPFHT....VRFD.S.WLHQ...............sMP......................................DN...IVRAK.GIA..W.CA.................TR...N....S..lAL...LMS........QAGP.A.VSIEP....V....S..Y......WVAAMpkleqeqikq......................................qepeiledwddQFGDRHTNLVFI.........GT....DLD....EAA....ITKELDQCL................................................................................
H3T057_PSEAE/259-349 ..........................................dsfhvdlpev-------.-.----EE....AALL.E.ALGEl..............vER......................................HD...ILRIK.GFA..A.IP.................GK...P....M...RL...LVQ........GVGK.R.FDRHF....D....R..K......WLAD-...........................................................--EARSTRLVVI.........GQ....ELD....QAA....IANQLRTAL................................................................................
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G4FLK5_9SYNE/262-358 ...............................................vvggn-----VR.F.EGVIQR....ADFE.R.ILPPf..............vTE......................................HQ...VVRLK.GRV..W.LP.................GK...S....L...PL...QVQ........MVGP.R.LETWF....E....A..A......PDQAW..........................................................tPQNQSGVDLVVI.........GF....DPK...aSEK....LT-------tlllqa..........................................................................
A5YSK6_9EURY/335-425 ....................................................VESFVYR.Q.QKPFNP....EQFD.S.WLSE................WN......................................GD...IIRMK.GFA..W.IS.................TR...P....E..tVL...GVS........QAGS.A.VQAGP....I....G..E......WGQD-...........................................................---DPATRLVII.........GQ....HLD....ITQ....ITADLDDCV................................................................................
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F8BPF8_OLICM/267-382 ....................................................VTSFVYR.A.RRPFEP....AKFH.Q.FLQE................SW......................................RG...VIRAK.GHF..W.LA.................TR...P....Q..wLG...ELS........QAGA.L.VKTEG....L....G..F......WWANVpmerwpndpf......................................wrqtvkkswneLYGDRRQEIVFI.........GT....GMD....EES....IRRRLDACL................................................................................
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Q63CD9_BACCZ/224-318 ....................................................VKSFVLR.E.ERPLDL....QKLN.E.WMSAvv............qeLG......................................EY...LYRYK.GIL..S.ID.................GV...D....K...RI...VFQ........GVHT.L.FAAS-....Y....D..R......EWQE-...........................................................-GEDRVSEVVFI.........GK....DIN....KEW....FQEHFEECV................................................................................
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I1B6P9_ECOLX/252-370 ..................................................wr----VIR.D.DRPFHP....QRLW.D.TCHR...............fMG......................................MG...VYRSK.GFF..W.LP.................GR...D....D..lAL...LWN........QSAG.S.ISLAL....I....G..Y......WKAGVlehtdnnltree..................................rsalqrhidtasgRFGDRCCQLTII.........GN....ATE....VND....FTHALSLCL................................................................................
H3PQB4_BRUAO/256-349 ....................................................FESFVVE.A.GSVADP....KAFA.E.KLKAv..............iAE......................................HD...ILRLK.GFV..D.VP.................GK...P....M...RL...VVQ........AVGP.R.IEHY-....F....D..R......PWGK-...........................................................-DETRSTRLVVI.........GL...hDID....EAA....IAQAVKDA-a...............................................................................
D8DV51_PREBR/1-94 ..................................................kw-------.-.------....----.-.----................-T......................................KN...IIRCK.GLV..Y.FR.................DE...Q....E..tCY...VFE........QAGK.Q.MNLTN....A....G..Q......WYATMpadelkqlle......................................nnpkvkaqwddKYGDRMQKLVFI.........GQ....HLD....REA....ITKGLDSCL................................................................................
G2UC87_PSEAI/284-374 ..........................................dsfhvdlpev-------.-.----EE....AALL.E.ALGEl..............vER......................................HD...ILRIK.GFA..A.IP.................GK...P....M...RL...LVQ........GVGK.R.FDRHF....D....R..K......WLAD-...........................................................--EVRSTRLVVI.........GQ....ELD....QAA....IANQLRTAL................................................................................
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Q3AXL4_SYNS9/256-353 ...............................................vigqg-----VR.M.EGDWDR....KALE.S.ILPEl..............vRQ......................................HQ...VIRLK.GRV..W.LA.................GK...P....L...PL...QLQ........MVGP.R.LNSWF....E....A..A......PKDAW..........................................................rPTSGTGVDLVVL.........AL...nDAA....SSA....LESGLQRL-l...............................................................................
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C3C0M6_BACTU/256-371 ....................................................INSFVYR.R.KYPFHP....ERLM.N.WLEK................WP......................................VD...IVRAK.GFF..W.LA.................SR...N....N..mIG...LLS........QAGS.S.ITIQG....A....G..E......WIAALpeternqmii......................................eepevlknwdkQYGDRITELVFI.........GI....DMN....RSF....IEQSLDDCL................................................................................
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F0N1I1_NEIMO/218-304 ...................................................s-QGFTFP.A.GRDFDG....EKLT.N.FFNDl.............pnMT......................................EG...LVRAK.GVF..Q.VL.................GT...-....-...WV...WLN........WVDG.Q.WGAN-....-....-..-......----Q...........................................................VSWRRDSRFELI.........AK....SFD....ADL....IEQKLKDAL................................................................................
H4FUT2_STAAU/212-294 ...............................................inhqf-----VQ.S.PAKCTK....AQFI.K.RLAC................LP......................................TH...IYRLK.GFM..T.FE.................DT...A....H...TY...LIQ........FTQG.Q.YELTP....V....A..F......SKKV-...........................................................-----PEYLVLI.........GK....GIS....KED....Y--------qcl.............................................................................
Q1LPE2_RALME/258-373 ....................................................IRSFVYG.A.RRPFHP....QRFH.A.FVAA................EW......................................PG...VVRSK.GFF..W.LA.................SH...P....T..lAG...TWS........QAGA.V.ARHGP....A....G..Y......WWAAVpperwpddpe......................................svalirakwddSVGDARQEIVLI.........GV....DMD....EFE....LRRCLDACL................................................................................
F9JR37_STAAU/212-294 ...............................................inhqf-----VQ.S.PAKCTK....AQFI.K.RLAC................LP......................................TH...IYRLK.GFM..T.FE.................DT...A....H...TY...LIQ........FTQG.Q.YELTP....V....A..F......SKKV-...........................................................-----PEYLVLI.........GK....GIS....KED....Y--------qcl.............................................................................
A1TFZ2_MYCVP/266-357 ....................................................ISSMTFH.S.DRPFHP....QRLA.E.SLGK................-M......................................TR...ILRSK.GFC..W.IA.................SR...P....T..iAA...IWS........QAGP.N.LVIEP....A....Q..Y......WSST-...........................................................-EIAPGQEIVFI.........GV....KLD....RDK....VRRLLEDAL................................................................................
H1S4Z9_9BURK/266-357 ...........................................fdsvvvtlg-------.-.--EVDR....DPLI.D.GLRQl..............vER......................................HT...IYRIK.GFA..S.LP.................AK...P....M...RL...VLH........GVGQ.R.FDSY-....F....D..R......RWRQ-...........................................................-GEAQSTRIVLI.........GQ....DLD....QPT....LQAALEAAL................................................................................
G9R836_9ENTR/241-323 ...................................................c--GWIFD.A.ETVFDT....IGLL.E.WARL................--......................................AP...VGRVK.GVM..R.IA.................EG...-....-...AV...RIN........RQGE.D.LHIE-....-....-..-......---TL...........................................................SVAPPDSRIELI.........SA...nEAD....WNA....LQTSLLR--lr..............................................................................
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D0AVV6_BRUAO/285-378 .................................................vks---VSLR.T.-GEIDP....AKFF.P.WIQNit............qtQG......................................PN...ILRLK.GII..A.FK.................DD...P....D...RY...VVQ........GVHM.I.IEGD-....H....Q..R......AWKP-...........................................................-EEKHESRLVFI.........GR....ELD....PAA....LKAGFENCR................................................................................
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G1Z6X0_ECOLX/240-323 ...................................................a-CGWIFD.A.DTVFDT....IGIL.E.WARL................--......................................AP...VERVK.GVL..R.IP.................EG...-....-...LV...RIN........RQGD.D.LHIE-....-....T..Q......-----...........................................................NVAPPDSRIELI.........SS...sEAD....WNA....LQSALLK--lr..............................................................................
D9WGV1_9ACTO/237-353 ....................................................VSTLVWR.R.RRPFHP....GRLY.D.ALED................LS......................................CA...AARSR.GRF..W.LA.................DR...G....D..tLL...SWD........AAGG.A.LCVES....A....G..P......WLAALpdaawemvpae.....................................rrvaasldwhpEHGDRCQHLTFT.........SP....ELD....RDG....LLALLDSCL................................................................................
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B6ZSV0_ECO57/224-317 ....................................................ISSIVVE.L.DYPVDI....SEVS.R.VMENll............leSA......................................DK...LLRYK.GML..W.ID.................GE...P....N...RL...LFQ........GVQR.L.YSAD-....W....D..R......PWGD-...........................................................--EKPHSTMVFI.........GI....QLP....EEE....IRAAFAG--lr..............................................................................
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