GenomeNet

Database: Pfam
Entry: ComX
LinkDB: ComX
Original site: ComX 
#=GF ID   ComX
#=GF AC   PF05952.7
#=GF DE   Bacillus competence pheromone ComX
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_4222 (release 9.0)
#=GF GA   19.80 19.80;
#=GF TC   19.80 20.50;
#=GF NC   19.70 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12067344
#=GF RT   Specific activation of the Bacillus quorum-sensing systems by
#=GF RT   isoprenylated pheromone variants. 
#=GF RA   Ansaldi M, Marolt D, Stebe T, Mandic-Mulec I, Dubnau D; 
#=GF RL   Mol Microbiol 2002;44:1561-1573.
#=GF DR   INTERPRO; IPR009233;
#=GF CC   Natural genetic competence in Bacillus subtilis is controlled by
#=GF CC   quorum-sensing (QS). The ComP- ComA two-component system detects
#=GF CC   the signalling molecule ComX, and this signal is transduced by a
#=GF CC   conserved phosphotransfer mechanism. ComX is synthesised as an
#=GF CC   inactive precursor and is then cleaved and modified by ComQ
#=GF CC   before export to the extracellular environment [1].
#=GF SQ   61
#=GS Q9K5K8_BACMO/1-53  AC Q9K5K8.1
#=GS B1HMR6_LYSSC/1-53  AC B1HMR6.1
#=GS E3IGW5_GEOS0/1-51  AC E3IGW5.1
#=GS H0FPS1_BACAM/1-54  AC H0FPS1.1
#=GS G6G7N6_9FIRM/1-54  AC G6G7N6.1
#=GS Q8VL67_BACMO/1-63  AC Q8VL67.1
#=GS COMX_BACIU/1-58    AC P0CY50.1
#=GS A8D477_BACIU/1-53  AC A8D477.1
#=GS G4P058_BACPN/1-57  AC G4P058.1
#=GS Q9K5K4_BACIU/1-57  AC Q9K5K4.1
#=GS D9YRJ7_BACLI/1-47  AC D9YRJ7.1
#=GS I0F8A9_9BACI/1-54  AC I0F8A9.1
#=GS Q8VQA2_BACIU/1-58  AC Q8VQA2.1
#=GS G0IJZ7_BACAM/1-58  AC G0IJZ7.1
#=GS Q9K5L2_BACIU/1-53  AC Q9K5L2.1
#=GS D7CZV6_GEOSC/1-51  AC D7CZV6.1
#=GS D4YAC7_BACTR/1-51  AC D4YAC7.1
#=GS D7WW60_9BACI/1-52  AC D7WW60.1
#=GS Q2XTA2_BACMO/1-58  AC Q2XTA2.1
#=GS A7Z883_BACA2/1-57  AC A7Z883.1
#=GS A3I6I8_9BACI/1-52  AC A3I6I8.1
#=GS E0TZW3_BACPZ/1-54  AC E0TZW3.1
#=GS B1HYU1_LYSSC/1-54  AC B1HYU1.1
#=GS C3EDN3_BACTU/1-55  AC C3EDN3.1
#=GS G4P3U7_BACIU/1-53  AC G4P3U7.1
#=GS H5Y5H0_9FIRM/1-55  AC H5Y5H0.1
#=GS Q9K5K2_BACMO/1-54  AC Q9K5K2.1
#=GS COMX_BACPN/1-58    AC P0CY51.1
#=GS A3IE45_9BACI/7-58  AC A3IE45.1
#=GS D7WXM5_9BACI/1-52  AC D7WXM5.1
#=GS Q9FAF0_BACIU/1-61  AC Q9FAF0.1
#=GS G4ERS6_BACIU/1-53  AC G4ERS6.1
#=GS Q9K5K5_BACIU/1-54  AC Q9K5K5.1
#=GS B4BSK0_9BACI/1-51  AC B4BSK0.1
#=GS Q9K5K3_BACMO/1-56  AC Q9K5K3.1
#=GS D4G0R3_BACNA/1-61  AC D4G0R3.1
#=GS G9LQ80_BACIU/1-55  AC G9LQ80.1
#=GS Q7B903_BACIU/1-57  AC Q7B903.1
#=GS A8FGX7_BACP2/1-56  AC A8FGX7.1
#=GS B7GGX4_ANOFW/1-52  AC B7GGX4.1
#=GS A8D470_BACIU/1-55  AC A8D470.1
#=GS E3DSP2_BACA1/1-70  AC E3DSP2.1
#=GS D9YRL0_BACLI/1-51  AC D9YRL0.1
#=GS B4AHS1_BACPU/1-46  AC B4AHS1.1
#=GS I0UK08_BACLI/1-54  AC I0UK08.1
#=GS Q8VLF8_BACMO/1-57  AC Q8VLF8.1
#=GS E5W7I1_9BACI/1-56  AC E5W7I1.1
#=GS F4EL13_BACAM/1-58  AC F4EL13.1
#=GS COMX_BACSU/1-55    AC P45453.1
#=GS B1HSJ6_LYSSC/1-49  AC B1HSJ6.1
#=GS Q8VQ62_BACLI/1-54  AC Q8VQ62.1
#=GS F0T1C5_SYNGF/1-53  AC F0T1C5.1
#=GS Q8VQA3_BACMO/1-54  AC Q8VQA3.1
#=GS Q65FH5_BACLD/1-54  AC Q65FH5.1
#=GS A3KLB6_BACAM/1-57  AC A3KLB6.1
#=GS D5MYQ4_BACPN/1-54  AC D5MYQ4.1
#=GS Q8VLG1_BACIU/1-57  AC Q8VLG1.1
#=GS Q9R9J4_BACIU/1-54  AC Q9R9J4.1
#=GS E8VK11_BACST/1-57  AC E8VK11.1
#=GS E1UP82_BACAS/1-58  AC E1UP82.1
#=GS F4E8Z7_BACAM/1-58  AC F4E8Z7.1
Q9K5K8_BACMO/1-53             ......M..-QEMVGYLIKYPNVLREVMEGNACLLGVDKD...QSECIINGFKGLEIYSMLD.--WK--y.............
B1HMR6_LYSSC/1-53             ......M..-RKLIQYLLENPSLIVSLKENKLSLVGVTTR...EQQAILEAFNEPIYF----.------rglgwrg.......
E3IGW5_GEOS0/1-51             ......M..-QEIIRFLVEHPEVIEKLQNGTVSLIGLSEL...EVKAVVKVFSEST------.------eplgywk.......
H0FPS1_BACAM/1-54             ......M..-QEIVGYLTKNPEVLNKVIEGNASLIGVSQD...QTDCVINAFKGIDVISFGG.-DW---ky............
G6G7N6_9FIRM/1-54             ......M..LQNVVEYLIENPDVKEKVKEGSASLVGLTKM...EQQAVIDSFEDEPS-----.------vvgplqyw......
Q8VL67_BACMO/1-63             meeitv-..KQDIVHYLMENPLVLTKLACGEASLIGVPDK...LLPAIVEIFERDLSQSKRCrGIFWEQ..............
COMX_BACIU/1-58               ......M..KQDMIDYLMKNPQVLTKLENGEASLIGIPDK...LIPSIVDIFNKKMTLSKKCkGIFWEQ..............
A8D477_BACIU/1-53             ......M..-QEMVGYLIKYPNVLREVMEGNACLLGVDND...QSECIINGFKGLEIYSMLD.--WK--y.............
G4P058_BACPN/1-57             ......MkhIDKIISHLVNNPEAFDQFKNGNLTLLNINEK...EKKAILYAFEEGEAPRTSN.--WPPI..............
Q9K5K4_BACIU/1-57             ......M..-QELISYLLKYPEVLKKLKSNEASLIGFSSD...ETQLIIEGFEGIEEVKRGNaGKWGP-e.............
D9YRJ7_BACLI/1-47             ......-..-------MVENPEVLKKVVDGDACLLGIDPE...KTGVVVDSI-RLLGKSWGGgGFW---i.............
I0F8A9_9BACI/1-54             ......M..-QEIVGYLVKNPEVLDEVMEGRASLLNIDKE...QLKSIVDAFRGLQIYTNGN.--WVP-s.............
Q8VQA2_BACIU/1-58             ......M..KQDMINYLMKNPQVLTKLENGEASLIGIPDK...LIPSLLGIFNREMTLSKKQkGIFWEQ..............
G0IJZ7_BACAM/1-58             ......M.kKQDIVNYLIENPRVIHQLEEGEVCLIGIPHS...IIPAIIEIFSNSTYKKKPEfTFW---dq............
Q9K5L2_BACIU/1-53             ......M..-QEMVGYLIKYPNVLREVMEGNACLLGVDKD...QSECIINGFKGLEIYSMMD.--W---hy............
D7CZV6_GEOSC/1-51             ......M..-QEIIRFLVEHPEVIEKLQNGTVSLIGLSEL...EVKAVVKVFSEST------.------eplgywk.......
D4YAC7_BACTR/1-51             ......M..-QEIIRFLVEHPEVIEKLQNGTVSLIGLSEL...EVKAVVKVFSEST------.------eplgywk.......
D7WW60_9BACI/1-52             ....mi-..--NMIQYLEQNPTLVTLLKEKKASLIGVTAL...EQKAILDSFDEELNLENRL.--W---n.............
Q2XTA2_BACMO/1-58             ......M..KQDMIDYLMKNPQVLTKLENGEASLIGIPDK...LIPSIVDIFNKKMTLSKKCkGIFWEQ..............
A7Z883_BACA2/1-57             ......M..-QEIVNYLVRNPEIVQKLRREEVSIIGLDKE...EVKGVLLGFDQLISMSSKDeIYWKP-s.............
A3I6I8_9BACI/1-52             ....mi-..--NVIQYLEKNPSLVALLKEQRASLIGISSI...EQMAILEAFIDEMNIESEI.--W---n.............
E0TZW3_BACPZ/1-54             ......M..-QEIVGYLVKYPEVLEEVMEGRASILNVNQE...QLKSIIDAFKGLQVASTVH.--WIP-s.............
B1HYU1_LYSSC/1-54             ....mi-..--NVIQYLEQNPSLVALLKEQRASLIGISSI...EQVAILEAFIDEMQMPIES.DIW---n.............
C3EDN3_BACTU/1-55             ......M..-KELMYYLSQNPELVYKLEKNELSLV-INPKwgvSNETIVNVLKK--------.------siatlrseywq...
G4P3U7_BACIU/1-53             ......M..-QEMVGYLIKYPNVLREVMEGNACLLGVDKD...QSECIINGFKGLEIYSMMD.--W---hy............
H5Y5H0_9FIRM/1-55             ......M..LQNVVEYLIQNPDVKERVQEGTASLIGLTEM...EQKAVHDVFESSGSTSEIPiEYW---..............
Q9K5K2_BACMO/1-54             ......M..-QEIVGYLVKNPEVLDEVMKGRASLLNIDKD...QLKSIVDAFGGLQIYTNGN.--WVP-s.............
COMX_BACPN/1-58               ......M..KQDMIDYLMKNPQVLTKLENGEASLIGIPDK...LIPSIVDIFNKKMTLSKKCkGIFWEQ..............
A3IE45_9BACI/7-58             ....mi-..--NMVQYLEQNPSLVTLLKEKKASLVGVTEL...EQKAILDSFDEDVCLESTI.--W---y.............
D7WXM5_9BACI/1-52             ....mi-..--NVIQYLEQNPSLVALLKEQKASLVGVSSV...EQTAILEAFSGEMNTESDI.--W---n.............
Q9FAF0_BACIU/1-61             ......MkhIDKIISHLVNNPEAFDQFKNGNLTLLNINEK...EKKAILYAFEQGEVPRTSK.--WPPIeais..........
G4ERS6_BACIU/1-53             ......M..-QEMVGYLIKYPNVLREVMEGNACLLGVDKD...QSECIIKGFKGLEIYSMMD.--W---hy............
Q9K5K5_BACIU/1-54             ......M..-QEIVGYLVKNPEVLDEVMEGRASLLNIDKD...QLKSIVDAFRGMQIYTNGN.--WVP-s.............
B4BSK0_9BACI/1-51             ......M..-QEMIRFLMENPEVIEKLKSGTVSLVGLDEL...EVQAIIKVFSQS-------.------vtplgywk......
Q9K5K3_BACMO/1-56             ......M..MQDLINYFLSYPEVLKKLKNREACLIGFSSN...ETETIIKAYNDYHLSSPTT.REW---dg............
D4G0R3_BACNA/1-61             ......MkhIDKIISHLVNNPEAFDQFKNGNLTLLNINEK...EKKAILYAFEQGEVPRTSK.--WPPIeais..........
G9LQ80_BACIU/1-55             ......M..-QDLINYFLNYPEALKKLKNKEACLIGFDVQ...ETETIIKAYNDYYLADPIT.RQWG--d.............
Q7B903_BACIU/1-57             ......M..-QELISYLLKYPEVIKKLKSNEASLIGFSPD...ETQLIIEGFEGTEEVKRGNaGKWGP-e.............
A8FGX7_BACP2/1-56             ......M.kIQELVSYLVENPSTLNQIVNGNASLLHVDQE...TASIIVDGFQKEDVIKAII.--WS--ta............
B7GGX4_ANOFW/1-52             ......M..MQQIIRFLVEHPEVIEKLQNGTVSLIGLSEL...EVKAVIKVFSESTS-----.------plgywr........
A8D470_BACIU/1-55             ......M..-QDLINYFLNYPEALKKLKNKEACLIGFDVQ...ETETIIKAYNDYYLADPIT.RQWG--d.............
E3DSP2_BACA1/1-70             ......MkhIDKIISHLANNPEAFDQFKNGNLTLLNINEK...EKKAILYAFEEGEVPRTSK.--WPP-yetisnffeddkrk
D9YRL0_BACLI/1-51             ......M..-QEIVSFLVEHPEVLEQVIAGKASLIGVDKD...QVFSLIEGFKRIE------.------agwgpyp.......
B4AHS1_BACPU/1-46             ......-..--------MGNPSALKQVANGNASLLHVDQV...TASIIVEGFQKEDTIRSKK.--WR--da............
I0UK08_BACLI/1-54             ......M..-QDIVNFLVQHPEVLEQVIKGNASLIGLDKD...QLISITEGFKEWESIGRR-.------vpvwg.........
Q8VLF8_BACMO/1-57             ......M..-QELISYLLKYPEVIKKLKSNEASLIGFSPD...ETQLIIEGFEGTEEVKRGNaGKWGP-e.............
E5W7I1_9BACI/1-56             ......M..-QEIVSFLVQHPEILEQVINGNACLLGVDID...QLESIIDGFKLLESS----.------igrpvpfwrs....
F4EL13_BACAM/1-58             ......M.kKQDIVNYLIENPRVIHQLEEGEVCLIGIPHS...IIPAIIEIFSNSTYKKKPEfTFW---dq............
COMX_BACSU/1-55               ......M..-QDLINYFLNYPEALKKLKNKEACLIGFDVQ...ETETIIKAYNDYYLADPIT.RQWG--d.............
B1HSJ6_LYSSC/1-49             ......-..---MVQYLEQNPSLVTLLKEKKASLVGVTEL...EQKAILDSFDEDVCLESTI.--W---y.............
Q8VQ62_BACLI/1-54             ......M..-QDIVNFLVENPEVLKKVVDGDACLLGIDPE...KTGVVVDSI-RLLGKSWGGgGFW---i.............
F0T1C5_SYNGF/1-53             ......M..LQKVVEYLVQNPDEKEKLIEGKLNLIGLTKV...EQKAVLDVLQSPDVISPL-.------lyw...........
Q8VQA3_BACMO/1-54             ......M..-QEIVGYLVKNPEVLDEVMKGRASLLNIDKD...PLKSIVDAFGGLQIYTNGN.--WVP-s.............
Q65FH5_BACLD/1-54             ......M..-QDIVNFLVENPEVLKKVVDGDACLLGIDPE...KTGVVVDSI-RLLGKSWGGgGFW---i.............
A3KLB6_BACAM/1-57             ......M..-QEIVNYLVRNPEIVQKLRREEVSIIGLDKE...EVKGVLLGFDQLISMSSKDeIYWKP-s.............
D5MYQ4_BACPN/1-54             ......M..-QEIVGYLVKYPEVLEEVMEGRASILNVNQE...QLKSIIDAFKGLQVASTVH.--WIP-s.............
Q8VLG1_BACIU/1-57             ......MkhIDKIISHLANNPEAFDQFKNGNLTLLNINEK...EKKAILYAFEEGEAPRTSN.--WPPI..............
Q9R9J4_BACIU/1-54             ......M..-QEIVGYLVKNPEVLDEVMEGRASLLNIDKD...QLKSIVDAFRGLQIYTNGN.--WVP-s.............
E8VK11_BACST/1-57             ......MkhIDKIISHLVNNPEAFDQFKNGNLTLLNINEK...EKKAILYAFEEGEAPRTSN.--WPPI..............
E1UP82_BACAS/1-58             ......M.kKQDIVNYLIENPRVIHQLEEGEVCLIGIPHS...IIPAIIEIFSNSTYKKKPEfTFW---dq............
F4E8Z7_BACAM/1-58             ......M.kKQDIVNYLIENPRVIHQLEEGEVCLIGIPHS...IIPAIIEIFSNSTYKKKPEfTFW---dq............
#=GC seq_cons                 ......M...Q-llsYLlcNP-VlcclppGcASLlGlscc...phpuIlcuFpphphhp.hp...W...p.............
//
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