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Database: Pfam
Entry: ComX
LinkDB: ComX
Original site: ComX 
#=GF ID   ComX
#=GF AC   PF05952.11
#=GF DE   Bacillus competence pheromone ComX
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_4222 (release 9.0)
#=GF GA   19.80 19.80;
#=GF TC   20.20 20.20;
#=GF NC   19.50 19.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12067344
#=GF RT   Specific activation of the Bacillus quorum-sensing systems by
#=GF RT   isoprenylated pheromone variants. 
#=GF RA   Ansaldi M, Marolt D, Stebe T, Mandic-Mulec I, Dubnau D; 
#=GF RL   Mol Microbiol 2002;44:1561-1573.
#=GF DR   INTERPRO; IPR009233;
#=GF CC   Natural genetic competence in Bacillus subtilis is controlled by
#=GF CC   quorum-sensing (QS). The ComP- ComA two-component system detects
#=GF CC   the signalling molecule ComX, and this signal is transduced by a
#=GF CC   conserved phosphotransfer mechanism. ComX is synthesised as an
#=GF CC   inactive precursor and is then cleaved and modified by ComQ
#=GF CC   before export to the extracellular environment [1].
#=GF SQ   17
#=GS COMX_BACSU/1-53           AC P45453.1
#=GS K6CCG9_BACAZ/1-52         AC K6CCG9.1
#=GS A0A0A5I474_9BACI/1-56     AC A0A0A5I474.1
#=GS B7GGX4_ANOFW/1-52         AC B7GGX4.1
#=GS A0A068DS05_9BACT/252-294  AC A0A068DS05.1
#=GS A0A150MC40_9BACI/1-51     AC A0A150MC40.1
#=GS A8FGX7_BACP2/1-53         AC A8FGX7.1
#=GS A0A0A2TJH9_9BACI/1-50     AC A0A0A2TJH9.1
#=GS X2GV45_9BACI/1-52         AC X2GV45.1
#=GS A0A150KLH1_9BACI/1-51     AC A0A150KLH1.1
#=GS H5Y5H0_9FIRM/1-53         AC H5Y5H0.1
#=GS Q65FH5_BACLD/1-54         AC Q65FH5.1
#=GS F0T1C5_SYNGF/1-53         AC F0T1C5.1
#=GS A0A0B0HER4_9BACI/1-50     AC A0A0B0HER4.1
#=GS J7IZ32_DESMD/1-50         AC J7IZ32.1
#=GS A0A160F6D7_9BACI/1-51     AC A0A160F6D7.1
#=GS L7VG85_9FLAO/252-298      AC L7VG85.1
COMX_BACSU/1-53                      ...M.QDLINYFLNYPEALKKLKNKEACLIGFDVQETETIIKAYN.........DYYLADPITR.QW................
K6CCG9_BACAZ/1-52                    .mi-.SEIIQHLVKNQEVLEQVQNGFASLVGVSEEEVQIILDVLN.........G---------.--tvttlssfw.......
A0A0A5I474_9BACI/1-56                ...MlQTVVEKLVESPDLLKQVREGNASLAGISETEKAAILDVFD.........----------.--ensqentvlgicyw..
B7GGX4_ANOFW/1-52                    ..mM.QQIIRFLVEHPEVIEKLQNGTVSLIGLSELEVKAVIKVFS.........----------.--estsplgywr......
A0A068DS05_9BACT/252-294             fth-.------LSKDPLCLKQVVNTNKCLLHLMKEKEQLIISSVI.........----------.--dnlvkg..........
A0A150MC40_9BACI/1-51                ...M.QEIIRFLVEHPEVIEKLQNGTVSLIGLSELEVKAVVKVFS.........----------.--esteplgywk......
A8FGX7_BACP2/1-53                    mki-.QELVSYLVENPSTLNQIVNGNASLLHVDQETASIIVD---.........GFQKEDVIKAiIW................
A0A0A2TJH9_9BACI/1-50                ...MlQKIVESLTNNPNLVEKLQEGKLSLIGVSETEEAAI-----.........----------.--kdvfttgsqdhsk...
X2GV45_9BACI/1-52                    ...M.KNIIHYLMKDTEVLHLLKNNKICIIGISPEENKALIDV--.........----------.--vlnkkpqlqayyw...
A0A150KLH1_9BACI/1-51                ...M.KEIIYNLIMNPEMKDQLKKGNLCLLTNNENERKVVLA---.........----------.--tlvgdevvnpley...
H5Y5H0_9FIRM/1-53                    ...MlQNVVEYLIQNPDVKERVQEGTASLIGLTEMEQKAV-----.........----------.--hdvfessgstseipie
Q65FH5_BACLD/1-54                    ...M.QDIVNFLVENPEVLKKVVDGDACLLGIDPEKTGVVVDSIRllgkswgggGF--------.--wi..............
F0T1C5_SYNGF/1-53                    ...MlQKVVEYLVQNPDEKEKLIEGKLNLIGLTKVEQKAVLDV--.........-LQSPDVI--.--spllyw..........
A0A0B0HER4_9BACI/1-50                ...M.QQIIRFLVEHPEAIEKLQNGTVSLIGLSELEIKAVIKVF-.........----------.--sestrplgyw......
J7IZ32_DESMD/1-50                    ...MlQNVVEYLIENPDVKEKVKEGSASLVGLTKMEQQAVIDSFE.........D---------.--epsvvgp.........
A0A160F6D7_9BACI/1-51                ...M.QQIIRFLVEHPEVIKKLQNGTVSLIGLSELEVKAVIKAFS.........----------.--estrslgywm......
L7VG85_9FLAO/252-298                 .ft-.-----FLSENPIHIKQVVNTNKCLLHIDKENGFLIISSVI.........----------.--dnllkgasgq......
#=GC seq_cons                        ...M.QpllpaLlcsP-slcplpsGsssLlGloc.Etpsllcsh.......................pssh............
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