GenomeNet

Database: Pfam
Entry: ComX
LinkDB: ComX
Original site: ComX 
#=GF ID   ComX
#=GF AC   PF05952.10
#=GF DE   Bacillus competence pheromone ComX
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_4222 (release 9.0)
#=GF GA   19.80 19.80;
#=GF TC   20.10 20.10;
#=GF NC   19.50 18.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12067344
#=GF RT   Specific activation of the Bacillus quorum-sensing systems by
#=GF RT   isoprenylated pheromone variants. 
#=GF RA   Ansaldi M, Marolt D, Stebe T, Mandic-Mulec I, Dubnau D; 
#=GF RL   Mol Microbiol 2002;44:1561-1573.
#=GF DR   INTERPRO; IPR009233;
#=GF CC   Natural genetic competence in Bacillus subtilis is controlled by
#=GF CC   quorum-sensing (QS). The ComP- ComA two-component system detects
#=GF CC   the signalling molecule ComX, and this signal is transduced by a
#=GF CC   conserved phosphotransfer mechanism. ComX is synthesised as an
#=GF CC   inactive precursor and is then cleaved and modified by ComQ
#=GF CC   before export to the extracellular environment [1].
#=GF SQ   13
#=GS X2GV45_9BACI/1-52         AC X2GV45.1
#=GS A0A0M9WT23_9BACI/1-51     AC A0A0M9WT23.1
#=GS Q65FH5_BACLD/1-54         AC Q65FH5.1
#=GS A0A0B1Y913_9BACI/1-50     AC A0A0B1Y913.1
#=GS F0T1C5_SYNGF/1-53         AC F0T1C5.1
#=GS J7IZ32_DESMD/1-50         AC J7IZ32.1
#=GS COMX_BACSU/1-53           AC P45453.1
#=GS K6CCG9_BACAZ/1-52         AC K6CCG9.1
#=GS B7GGX4_ANOFW/1-52         AC B7GGX4.1
#=GS L7VG85_9FLAO/252-298      AC L7VG85.1
#=GS A0A068DS05_9BACT/252-294  AC A0A068DS05.1
#=GS A8FGX7_BACP2/1-53         AC A8FGX7.1
#=GS A0A0N0S2H0_9BACI/1-52     AC A0A0N0S2H0.1
X2GV45_9BACI/1-52                    ...M.KNIIHYLMKDTEVLHLLKNNKICIIGISPEENKALIDV--.........----------.--vlnkkpqlqayyw
A0A0M9WT23_9BACI/1-51                ...M.INMIQFLEQNPSLVTLLKEKKASLVGVTELEQKAILESFD.........G---------.--dlrigngiw....
Q65FH5_BACLD/1-54                    ...M.QDIVNFLVENPEVLKKVVDGDACLLGIDPEKTGVVVDSIRllgkswgggGF--------.--wi...........
A0A0B1Y913_9BACI/1-50                ...M.INMVQYLEQNPSLVTLLKEKKASLVGVTELEQKAILDSFD.........----------.--edvrleygl....
F0T1C5_SYNGF/1-53                    ...MlQKVVEYLVQNPDEKEKLIEGKLNLIGLTKVEQKAVLDV--.........-LQSPDVI--.--spllyw.......
J7IZ32_DESMD/1-50                    ...MlQNVVEYLIENPDVKEKVKEGSASLVGLTKMEQQAVIDSFE.........D---------.--epsvvgp......
COMX_BACSU/1-53                      ...M.QDLINYFLNYPEALKKLKNKEACLIGFDVQETETIIKAYN.........DYYLADPITR.QW.............
K6CCG9_BACAZ/1-52                    .mi-.SEIIQHLVKNQEVLEQVQNGFASLVGVSEEEVQIILDVLN.........G---------.--tvttlssfw....
B7GGX4_ANOFW/1-52                    ..mM.QQIIRFLVEHPEVIEKLQNGTVSLIGLSELEVKAVIKVFS.........----------.--estsplgywr...
L7VG85_9FLAO/252-298                 .ft-.-----FLSENPIHIKQVVNTNKCLLHIDKENGFLIISSVI.........----------.--dnllkgasgq...
A0A068DS05_9BACT/252-294             fth-.------LSKDPLCLKQVVNTNKCLLHLMKEKEQLIISSVI.........----------.--dnlvkg.......
A8FGX7_BACP2/1-53                    mki-.QELVSYLVENPSTLNQIVNGNASLLHVDQETASIIVD---.........GFQKEDVIKAiIW.............
A0A0N0S2H0_9BACI/1-52                ...M.INVIQHLEKNPELVALLKEQKASLIGISAIEQKAILDSFE.........----------.--ekvclengfwn..
#=GC seq_cons                        ...M.ppllpaLhcNP-llcplpsspAsLlGloc.EppsIlDuhp......................p.hhh........
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