GenomeNet

Database: Pfam
Entry: Cu_amine_oxidN1
LinkDB: Cu_amine_oxidN1
Original site: Cu_amine_oxidN1 
#=GF ID   Cu_amine_oxidN1
#=GF AC   PF07833.7
#=GF DE   Copper amine oxidase N-terminal domain
#=GF AU   Fenech M
#=GF SE   Pfam-B_46519 (release 14.0)
#=GF GA   21.70 21.70;
#=GF TC   21.70 21.70;
#=GF NC   21.60 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Amine_oxidase_(copper-containing)
#=GF RN   [1]
#=GF RM   8591028
#=GF RT   Crystal structure of a quinoenzyme: copper amine oxidase of
#=GF RT   Escherichia coli at 2 A resolution. 
#=GF RA   Parsons MR, Convery MA, Wilmot CM, Yadav KD, Blakeley V, Corner
#=GF RA   AS, Phillips SE, McPherson MJ, Knowles PF; 
#=GF RL   Structure 1995;3:1171-1184.
#=GF RN   [2]
#=GF RM   10576737
#=GF RT   Visualization of dioxygen bound to copper during enzyme
#=GF RT   catalysis. 
#=GF RA   Wilmot CM, Hajdu J, McPherson MJ, Knowles PF, Phillips SE; 
#=GF RL   Science 1999;286:1724-1728.
#=GF DR   INTERPRO; IPR012854;
#=GF DR   SCOP; 1spu; sf;
#=GF CC   Copper amine oxidases catalyse the oxidative deamination  of
#=GF CC   primary amines to the corresponding aldehydes, while reducing
#=GF CC   molecular oxygen to hydrogen peroxide. These  enzymes are dimers
#=GF CC   of identical subunits, each comprising four domains. The
#=GF CC   N-terminal domain, which is absent in  some amine oxidases,
#=GF CC   consists of a five-stranded antiparallel beta sheet twisted
#=GF CC   around an alpha helix. The D1 domains from the two subunits
#=GF CC   comprise the 'stalk' of the mushroom-shaped dimer, and interact
#=GF CC   with each other but do not pack tightly against each other
#=GF CC   [1,2].
#=GF SQ   6356
#=GS U7UVH2_9FIRM/146-221      AC U7UVH2.1
#=GS E4KX29_9FIRM/1-100        AC E4KX29.1
#=GS W8U336_PAEPO/84-154       AC W8U336.1
#=GS AMO_ECOLI/33-121          AC P46883.1
#=GS AMO_ECOLI/33-121          DR PDB; 1SPU A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WGQ A; 5-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1JRQ A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WO0 A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1D6U B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1QAF B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1QAL A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WOF A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1OAC A; 5-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1OAC B; 5-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1QAF A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1QAK A; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1LVN B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1D6Y A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1D6U A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WO0 B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1DYU A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1LVN A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WGQ B; 5-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1DYU B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1QAL B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1D6Z A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WOH B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1QAK B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WOH A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1D6Y B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2WOF B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2W0Q B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1D6Z B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1JRQ B; 6-91;
#=GS AMO_ECOLI/33-121          DR PDB; 2W0Q A; 7-91;
#=GS AMO_ECOLI/33-121          DR PDB; 1SPU B; 6-91;
#=GS A0A014X8D6_ACIBA/37-124   AC A0A014X8D6.1
#=GS V3MPY2_KLEPN/33-119       AC V3MPY2.1
#=GS A0A022S687_ACIBA/37-124   AC A0A022S687.1
#=GS A3DH87_CLOTH/37-114       AC A3DH87.1
#=GS S9SL47_PAEAL/110-202      AC S9SL47.1
#=GS I0BN95_9BACL/32-101       AC I0BN95.1
#=GS A0A022D5Y6_ACIBA/37-124   AC A0A022D5Y6.1
#=GS W4CD10_9BACL/47-139       AC W4CD10.1
#=GS C7HGN2_CLOTM/8-71         AC C7HGN2.1
#=GS B5Y6P8_COPPD/1532-1624    AC B5Y6P8.1
#=GS C7HHP8_CLOTM/18-144       AC C7HHP8.1
#=GS Q67QR9_SYMTH/214-306      AC Q67QR9.1
#=GS C9RCC2_AMMDK/57-163       AC C9RCC2.1
#=GS A0A031UVA7_KLEPN/33-119   AC A0A031UVA7.1
#=GS B1I2Z2_DESAP/8-90         AC B1I2Z2.1
#=GS C2CIB1_9FIRM/146-256      AC C2CIB1.1
#=GS N2FFR6_ECOLX/33-121       AC N2FFR6.1
#=GS A8MJ36_ALKOO/250-338      AC A8MJ36.1
#=GS W8YS54_9BACL/48-144       AC W8YS54.1
#=GS B1HMJ9_LYSSC/46-139       AC B1HMJ9.1
#=GS E3EBY4_PAEPS/66-154       AC E3EBY4.1
#=GS U7V2I8_9FIRM/19-69        AC U7V2I8.1
#=GS E6Q5N2_9ZZZZ/54-146       AC E6Q5N2.1
#=GS W4BJY6_9BACL/172-264      AC W4BJY6.1
#=GS B1I2L9_DESAP/54-146       AC B1I2L9.1
#=GS B0KCN8_THEP3/12-70        AC B0KCN8.1
#=GS I0VMW2_ECOLX/33-121       AC I0VMW2.1
#=GS A0A013HEH3_ACIBA/37-124   AC A0A013HEH3.1
#=GS W4BGI1_9BACL/50-143       AC W4BGI1.1
#=GS D7CQ03_SYNLT/58-161       AC D7CQ03.1
#=GS R9TPZ8_9CAUD/5-86         AC R9TPZ8.1
#=GS W4BQM1_9BACL/51-149       AC W4BQM1.1
#=GS L5MZK7_9BACL/644-712      AC L5MZK7.1
#=GS H5N8S5_ECOLX/33-121       AC H5N8S5.1
#=GS C6D4Y8_PAESJ/48-142       AC C6D4Y8.1
#=GS L0EAK3_THECK/18-75        AC L0EAK3.1
#=GS S7WKG0_9GAMM/54-141       AC S7WKG0.1
#=GS A0A015GVW7_ACIBA/37-124   AC A0A015GVW7.1
#=GS A0A021Y369_ACIBA/37-125   AC A0A021Y369.1
#=GS G4HHP4_9BACL/276-369      AC G4HHP4.1
#=GS A5D4A4_PELTS/11-78        AC A5D4A4.1
#=GS Y1MI80_9ENTR/33-121       AC Y1MI80.1
#=GS A8RUU5_CLOBW/9-76         AC A8RUU5.1
#=GS G5YG13_ECOLX/33-121       AC G5YG13.1
#=GS D1NKQ2_CLOTM/15-72        AC D1NKQ2.1
#=GS L3LK34_ECOLX/33-121       AC L3LK34.1
#=GS U4MM26_CLOTM/59-151       AC U4MM26.1
#=GS G7VRM6_PAETH/387-479      AC G7VRM6.1
#=GS A4J2I0_DESRM/48-140       AC A4J2I0.1
#=GS W8ZS21_9BACL/46-145       AC W8ZS21.1
#=GS W3NMC4_ACIBA/37-124       AC W3NMC4.1
#=GS A0A026HVV9_ECOLX/33-121   AC A0A026HVV9.1
#=GS A0A010FG14_ACIBA/37-125   AC A0A010FG14.1
#=GS H3SFT0_9BACL/35-125       AC H3SFT0.1
#=GS G4HAD5_9BACL/153-245      AC G4HAD5.1
#=GS S9SNK2_PAEAL/21-85        AC S9SNK2.1
#=GS W7RZ57_LYSSH/3-72         AC W7RZ57.1
#=GS W4D097_9BACL/119-176      AC W4D097.1
#=GS C8W0P7_DESAS/28-89        AC C8W0P7.1
#=GS R5ZQU8_9FIRM/64-164       AC R5ZQU8.1
#=GS W8YJX7_9BACL/24-72        AC W8YJX7.1
#=GS S3AZ78_9BACL/22-83        AC S3AZ78.1
#=GS H4ZCY4_ECOLX/33-121       AC H4ZCY4.1
#=GS A0A013NTC4_ACIBA/37-124   AC A0A013NTC4.1
#=GS S9TPL8_PAEAL/400-492      AC S9TPL8.1
#=GS W7YFY4_9BACL/63-140       AC W7YFY4.1
#=GS W9SUA4_KLEPN/33-119       AC W9SUA4.1
#=GS A0A009ULB2_ACIBA/37-124   AC A0A009ULB2.1
#=GS R8VUH2_9CLOT/54-141       AC R8VUH2.1
#=GS Y1GL49_9ENTR/33-121       AC Y1GL49.1
#=GS R5ADA4_9FIRM/1096-1226    AC R5ADA4.1
#=GS S9SRL2_PAEAL/48-140       AC S9SRL2.1
#=GS H4WAC9_ECOLX/33-121       AC H4WAC9.1
#=GS K6DKK1_BACAZ/48-140       AC K6DKK1.1
#=GS M9ERZ9_ECOLX/33-121       AC M9ERZ9.1
#=GS M4RAT6_ACIBA/37-124       AC M4RAT6.1
#=GS H3SDA8_9BACL/74-145       AC H3SDA8.1
#=GS R6PPJ5_9FIRM/9-68         AC R6PPJ5.1
#=GS S9T5H9_PAEAL/73-154       AC S9T5H9.1
#=GS A4XHM2_CALS8/52-139       AC A4XHM2.1
#=GS R7BY57_9FIRM/81-165       AC R7BY57.1
#=GS D7N6H2_9FIRM/677-778      AC D7N6H2.1
#=GS U2TTU7_9FIRM/75-174       AC U2TTU7.1
#=GS A0A009UAI4_ACIBA/37-125   AC A0A009UAI4.1
#=GS H0U8A4_BRELA/76-167       AC H0U8A4.1
#=GS G0VWR5_PAEPO/62-155       AC G0VWR5.1
#=GS W4BF04_9BACL/470-547      AC W4BF04.1
#=GS A0A011FPT1_ACIBA/37-124   AC A0A011FPT1.1
#=GS E0NKE7_9FIRM/472-568      AC E0NKE7.1
#=GS H5GBQ0_ECOLX/33-121       AC H5GBQ0.1
#=GS G8M1F1_CLOCD/52-151       AC G8M1F1.1
#=GS N8X6V8_9GAMM/37-125       AC N8X6V8.1
#=GS S7CDJ9_KLEPN/33-119       AC S7CDJ9.1
#=GS E3EKP3_PAEPS/54-160       AC E3EKP3.1
#=GS C9RB91_AMMDK/169-219      AC C9RB91.1
#=GS A0A022F3U4_ACIBA/37-124   AC A0A022F3U4.1
#=GS K4LQS0_THEPS/637-714      AC K4LQS0.1
#=GS W8YZY9_9BACL/135-186      AC W8YZY9.1
#=GS D1NR67_CLOTM/17-133       AC D1NR67.1
#=GS H8EGX3_CLOTM/30-138       AC H8EGX3.1
#=GS D3EEJ0_GEOS4/51-143       AC D3EEJ0.1
#=GS H5CKN2_ECOLX/33-121       AC H5CKN2.1
#=GS E8UW05_THEBF/112-206      AC E8UW05.1
#=GS G4HMN1_9BACL/51-144       AC G4HMN1.1
#=GS D5WXG7_KYRT2/23-127       AC D5WXG7.1
#=GS U1Y6Z1_ANEAE/33-102       AC U1Y6Z1.1
#=GS A0A011HLR4_ACIBA/37-124   AC A0A011HLR4.1
#=GS N8V2K8_ACIBA/37-124       AC N8V2K8.1
#=GS R4KPP6_9FIRM/58-151       AC R4KPP6.1
#=GS R6MAG7_9FIRM/55-149       AC R6MAG7.1
#=GS H5D1Y2_ECOLX/33-121       AC H5D1Y2.1
#=GS S9UAF8_PAEAL/37-129       AC S9UAF8.1
#=GS Z5L5Q4_KLEPN/33-119       AC Z5L5Q4.1
#=GS F8FJ30_PAEMK/732-812      AC F8FJ30.1
#=GS H8EDM0_CLOTM/24-92        AC H8EDM0.1
#=GS C9RDF9_AMMDK/978-1033     AC C9RDF9.1
#=GS K6DFA2_BACAZ/47-139       AC K6DFA2.1
#=GS H1CMA5_9FIRM/243-336      AC H1CMA5.1
#=GS R5ABL3_9FIRM/23-78        AC R5ABL3.1
#=GS E0IDU2_9BACL/46-138       AC E0IDU2.1
#=GS F8FQD7_PAEMK/348-437      AC F8FQD7.1
#=GS D3T7G4_THEIA/61-157       AC D3T7G4.1
#=GS H8EH02_CLOTM/30-78        AC H8EH02.1
#=GS U6SKR6_9BACI/116-208      AC U6SKR6.1
#=GS W1EY56_ECOLX/33-121       AC W1EY56.1
#=GS S7HCR1_KLEPN/33-119       AC S7HCR1.1
#=GS F8K7Y3_STRPY/412-522      AC F8K7Y3.1
#=GS X4ZIU4_9BACL/724-808      AC X4ZIU4.1
#=GS M8WYX6_ECOLX/33-121       AC M8WYX6.1
#=GS B0NZB5_9CLOT/64-164       AC B0NZB5.1
#=GS W4DAQ6_9BACL/398-490      AC W4DAQ6.1
#=GS F8FIZ8_PAEMK/66-120       AC F8FIZ8.1
#=GS W4V8U7_9CLOT/22-92        AC W4V8U7.1
#=GS A0A009GPD5_ACIBA/37-124   AC A0A009GPD5.1
#=GS R6MNH7_9FIRM/47-145       AC R6MNH7.1
#=GS W4VCP4_9CLOT/11-78        AC W4VCP4.1
#=GS I0BN79_9BACL/25-86        AC I0BN79.1
#=GS W4CWM2_9BACL/54-147       AC W4CWM2.1
#=GS M8DF43_9BACL/24-87        AC M8DF43.1
#=GS U4WNK0_BRELA/48-138       AC U4WNK0.1
#=GS M8JP85_ACIBA/37-124       AC M8JP85.1
#=GS F3MF42_9BACL/8-83         AC F3MF42.1
#=GS D3EEY4_GEOS4/51-137       AC D3EEY4.1
#=GS V5X376_PAEPO/757-833      AC V5X376.1
#=GS C8W4T4_DESAS/45-136       AC C8W4T4.1
#=GS E0RMM0_PAEP6/61-145       AC E0RMM0.1
#=GS W4DJ66_9BACL/49-141       AC W4DJ66.1
#=GS F1TF04_9CLOT/48-141       AC F1TF04.1
#=GS E6US62_CLOTL/37-114       AC E6US62.1
#=GS I7L211_PAEPO/48-140       AC I7L211.1
#=GS V5X0W0_PAEPO/84-155       AC V5X0W0.1
#=GS R8VUS8_9CLOT/51-147       AC R8VUS8.1
#=GS M1MG87_9CLOT/92-180       AC M1MG87.1
#=GS W8T712_EUBAC/63-139       AC W8T712.1
#=GS A0A037Z3P4_CLOTT/83-174   AC A0A037Z3P4.1
#=GS W4C3E9_9BACL/45-106       AC W4C3E9.1
#=GS A0A017H7F7_9FUSO/407-517  AC A0A017H7F7.1
#=GS H3SDA8_9BACL/115-207      AC H3SDA8.1
#=GS A0A014F782_ACIBA/37-124   AC A0A014F782.1
#=GS E6UQ39_CLOTL/13-74        AC E6UQ39.1
#=GS F8FN43_PAEMK/368-459      AC F8FN43.1
#=GS D1NR24_CLOTM/65-150       AC D1NR24.1
#=GS W4V517_9CLOT/50-142       AC W4V517.1
#=GS N2DU76_ECOLX/33-121       AC N2DU76.1
#=GS K9AK04_9BACI/43-133       AC K9AK04.1
#=GS E6UQ28_CLOTL/49-141       AC E6UQ28.1
#=GS S1WT77_KLEPN/33-119       AC S1WT77.1
#=GS A0A010BVE6_ACIBA/37-124   AC A0A010BVE6.1
#=GS E1L437_9FIRM/72-169       AC E1L437.1
#=GS A3DGH5_CLOTH/13-74        AC A3DGH5.1
#=GS S3AHG4_9BACL/386-465      AC S3AHG4.1
#=GS S3AJD6_9BACL/285-377      AC S3AJD6.1
#=GS K6M196_ACIBA/37-125       AC K6M196.1
#=GS E6UM04_CLOTL/59-151       AC E6UM04.1
#=GS F3MJX4_9BACL/377-469      AC F3MJX4.1
#=GS I1Y0B1_ACIBA/37-124       AC I1Y0B1.1
#=GS N8UYZ5_9GAMM/37-125       AC N8UYZ5.1
#=GS F8FBS8_PAEMK/4-90         AC F8FBS8.1
#=GS A0A024ZQ41_ECOLX/33-121   AC A0A024ZQ41.1
#=GS W8T3S9_EUBAC/228-290      AC W8T3S9.1
#=GS S9U4B2_PAEAL/15-80        AC S9U4B2.1
#=GS W8TCK4_PAEPO/51-149       AC W8TCK4.1
#=GS G4HM86_9BACL/90-160       AC G4HM86.1
#=GS R6MF96_9FIRM/1-81         AC R6MF96.1
#=GS W8YZY9_9BACL/53-165       AC W8YZY9.1
#=GS A0A013QHT6_ACIBA/37-124   AC A0A013QHT6.1
#=GS A0A025GZH3_ECOLX/33-121   AC A0A025GZH3.1
#=GS D8FJH9_9FIRM/42-133       AC D8FJH9.1
#=GS A0A013WC89_ACIBA/37-124   AC A0A013WC89.1
#=GS H0U563_BRELA/29-114       AC H0U563.1
#=GS W4CDK1_9BACL/414-469      AC W4CDK1.1
#=GS M5JH49_9BACI/168-258      AC M5JH49.1
#=GS C6D4T1_PAESJ/22-85        AC C6D4T1.1
#=GS R5HTV9_9FIRM/52-169       AC R5HTV9.1
#=GS A0A013YJY5_ACIBA/37-124   AC A0A013YJY5.1
#=GS C6J7L5_9BACL/66-157       AC C6J7L5.1
#=GS W4VA84_9CLOT/21-68        AC W4VA84.1
#=GS C6CYT3_PAESJ/22-94        AC C6CYT3.1
#=GS B7LYM7_ECO8A/33-121       AC B7LYM7.1
#=GS F2JHG4_CELLD/605-699      AC F2JHG4.1
#=GS A6TU19_ALKMQ/68-163       AC A6TU19.1
#=GS A0A026QTV7_ECOLX/33-121   AC A0A026QTV7.1
#=GS W4CRM7_9BACL/209-242      AC W4CRM7.1
#=GS S7A509_KLEPN/33-119       AC S7A509.1
#=GS V3MKI5_KLEPN/33-119       AC V3MKI5.1
#=GS F5LSD2_9BACL/327-379      AC F5LSD2.1
#=GS H8ER16_CLOTM/89-179       AC H8ER16.1
#=GS R7BBG2_9CLOT/200-287      AC R7BBG2.1
#=GS K4LHM4_THEPS/107-178      AC K4LHM4.1
#=GS B2A1B9_NATTJ/618-706      AC B2A1B9.1
#=GS F6DQ35_DESRL/21-89        AC F6DQ35.1
#=GS K4ZP12_PAEAL/86-178       AC K4ZP12.1
#=GS W4ADV8_9BACL/159-251      AC W4ADV8.1
#=GS F5LEC4_9BACL/63-136       AC F5LEC4.1
#=GS E6URG4_CLOTL/66-150       AC E6URG4.1
#=GS L8BUX6_ECOLX/33-121       AC L8BUX6.1
#=GS L0K8M1_HALHC/47-139       AC L0K8M1.1
#=GS E5YRJ6_9BACL/49-141       AC E5YRJ6.1
#=GS A0A013NJC5_ACIBA/37-125   AC A0A013NJC5.1
#=GS E0IEV9_9BACL/273-366      AC E0IEV9.1
#=GS T8WQ87_ECOLX/33-121       AC T8WQ87.1
#=GS G7VX58_PAETH/125-202      AC G7VX58.1
#=GS V3GS03_ENTCL/33-121       AC V3GS03.1
#=GS V3CNE4_KLEPN/33-119       AC V3CNE4.1
#=GS A0A010EVZ9_ACIBA/37-124   AC A0A010EVZ9.1
#=GS C8W6A8_DESAS/317-408      AC C8W6A8.1
#=GS A0A013JXU5_ACIBA/37-125   AC A0A013JXU5.1
#=GS A0A025C869_ECOLX/33-121   AC A0A025C869.1
#=GS B6FYK4_9FIRM/72-182       AC B6FYK4.1
#=GS F6DP50_DESRL/45-112       AC F6DP50.1
#=GS K1EAC9_ACIBA/37-124       AC K1EAC9.1
#=GS A0A011E2Z6_ACIBA/37-124   AC A0A011E2Z6.1
#=GS G4HEW2_9BACL/339-431      AC G4HEW2.1
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#=GS N2NHB4_ECOLX/33-121       AC N2NHB4.1
#=GS S9TRU6_PAEAL/62-167       AC S9TRU6.1
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#=GS E3EF99_PAEPS/410-504      AC E3EF99.1
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#=GS W4C208_9BACL/401-493      AC W4C208.1
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#=GS K0BM49_ECO1E/33-121       AC K0BM49.1
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