#=GF ID DASH_Dad1
#=GF AC PF08649.5
#=GF DE DASH complex subunit Dad1
#=GF AU Wood V, Finn RD
#=GF SE Manual
#=GF GA 27.50 27.50;
#=GF TC 27.70 27.70;
#=GF NC 27.00 27.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 11799062
#=GF RT The mitotic spindle is required for loading of the DASH complex
#=GF RT onto the kinetochore.
#=GF RA Li Y, Bachant J, Alcasabas AA, Wang Y, Qin J, Elledge SJ;
#=GF RL Genes Dev 2002;16:183-197.
#=GF RN [2]
#=GF RM 15640796
#=GF RT The yeast DASH complex forms closed rings on microtubules.
#=GF RA Miranda JJ, De Wulf P, Sorger PK, Harrison SC;
#=GF RL Nat Struct Mol Biol. 2005;12:138-143.
#=GF RN [3]
#=GF RM 15664196
#=GF RT Formation of a dynamic kinetochore- microtubule interface
#=GF RT through assembly of the Dam1 ring complex.
#=GF RA Westermann S, Avila-Sakar A, Wang HW, Niederstrasser H, Wong J,
#=GF RA Drubin DG, Nogales E, Barnes G;
#=GF RL Mol Cell. 2005;17:277-290.
#=GF RN [4]
#=GF RM 15632076
#=GF RT Genetic analysis of the kinetochore DASH complex reveals an
#=GF RT antagonistic relationship with the ras/protein kinase A pathway
#=GF RT and a novel subunit required for Ask1 association.
#=GF RA Li JM, Li Y, Elledge SJ;
#=GF RL Mol Cell Biol. 2005;25:767-778.
#=GF RN [5]
#=GF RM 16079915
#=GF RT The DASH complex and Klp5/Klp6 kinesin coordinate bipolar
#=GF RT chromosome attachment in fission yeast.
#=GF RA Sanchez-Perez I, Renwick SJ, Crawley K, Karig I, Buck V, Meadows
#=GF RA JC, Franco-Sanchez A, Fleig U, Toda T, Millar JB;
#=GF RL EMBO J. 2005;24:2931-2943.
#=GF DR INTERPRO; IPR013958;
#=GF CC The DASH complex is a ~10 subunit microtubule-binding complex
#=GF CC that is transferred to the kinetochore prior to mitosis [1]. In
#=GF CC Saccharomyces cerevisiae DASH forms both rings and spiral
#=GF CC structures on microtubules in vitro [2,3]. Components of the
#=GF CC DASH complex, including Dam1, Duo1, Spc34, Dad1 and Ask1, are
#=GF CC essential and connect the centromere to the plus end of spindle
#=GF CC microtubules [4]. Throughout the cell cycle Dad1 remains bound
#=GF CC to kinetochores throughout the cell cycle and its association is
#=GF CC dependent on the Mis6 and Mal2 [5].
#=GF SQ 108
#=GS E3QWE4_COLGM/21-78 AC E3QWE4.1
#=GS E9D5W5_COCPS/11-68 AC E9D5W5.1
#=GS G4TNY7_PIRID/10-68 AC G4TNY7.1
#=GS C0NPJ7_AJECG/20-77 AC C0NPJ7.1
#=GS G0RYE9_CHATD/18-75 AC G0RYE9.1
#=GS B8NL09_ASPFN/15-72 AC B8NL09.1
#=GS F2TUF5_AJEDA/5-54 AC F2TUF5.1
#=GS F8MNJ9_NEUT8/19-76 AC F8MNJ9.1
#=GS Q8X057_NEUCS/19-76 AC Q8X057.1
#=GS Q1K5F6_NEUCR/19-76 AC Q1K5F6.1
#=GS B3LGP7_YEAS1/18-75 AC B3LGP7.1
#=GS D6RP18_COPC7/9-66 AC D6RP18.1
#=GS F0X6T6_GROCL/22-79 AC F0X6T6.1
#=GS B6HKQ0_PENCW/18-75 AC B6HKQ0.1
#=GS DAD1_YARLI/14-71 AC Q6CER3.1
#=GS G8YC64_PICSO/6-63 AC G8YC64.1
#=GS C8VKD3_EMENI/13-70 AC C8VKD3.1
#=GS G3XNP8_ASPNA/15-72 AC G3XNP8.1
#=GS I1RA08_GIBZE/17-74 AC I1RA08.1
#=GS C5DED1_LACTC/20-77 AC C5DED1.1
#=GS A1CBZ1_ASPCL/11-68 AC A1CBZ1.1
#=GS G8BNL1_TETPH/33-90 AC G8BNL1.1
#=GS E4ZRA0_LEPMJ/19-76 AC E4ZRA0.1
#=GS Q5B9U4_EMENI/13-79 AC Q5B9U4.1
#=GS G7XUU5_ASPKW/15-72 AC G7XUU5.1
#=GS F7WA01_SORMK/19-70 AC F7WA01.1
#=GS Q5KG80_CRYNJ/18-75 AC Q5KG80.1
#=GS E3K7D7_PUCGT/26-83 AC E3K7D7.1
#=GS DAD1_ASHGO/18-75 AC Q75E95.1
#=GS C9SAI6_VERA1/18-75 AC C9SAI6.1
#=GS F4RVG4_MELLP/27-81 AC F4RVG4.1
#=GS A5E1R1_LODEL/5-62 AC A5E1R1.1
#=GS G9MM21_HYPVG/15-72 AC G9MM21.1
#=GS G3JEJ6_CORMM/17-74 AC G3JEJ6.1
#=GS C5JUR1_AJEDS/28-84 AC C5JUR1.1
#=GS DAD1_YEAST/18-75 AC Q12248.1
#=GS C5FXM8_ARTOC/22-79 AC C5FXM8.1
#=GS G2QPE8_THIHA/17-74 AC G2QPE8.1
#=GS E6ZRN1_SPORE/32-89 AC E6ZRN1.1
#=GS C4YFV5_CANAW/12-69 AC C4YFV5.1
#=GS G3B3Q6_CANTC/2-59 AC G3B3Q6.1
#=GS DAD1_DEBHA/6-63 AC Q6BL27.1
#=GS F0UNW2_AJEC8/17-68 AC F0UNW2.1
#=GS C5PEN3_COCP7/11-68 AC C5PEN3.1
#=GS H2AV66_KAZAF/29-86 AC H2AV66.1
#=GS G2WWM7_VERDV/528-585 AC G2WWM7.1
#=GS I1BIU5_RHIO9/5-62 AC I1BIU5.1
#=GS G3ANX2_SPAPN/17-74 AC G3ANX2.1
#=GS B0Y296_ASPFC/33-87 AC B0Y296.1
#=GS C5GMU6_AJEDR/26-82 AC C5GMU6.1
#=GS Q2GV97_CHAGB/44-88 AC Q2GV97.1
#=GS C8Z4T6_YEAS8/18-75 AC C8Z4T6.1
#=GS G0V7Z8_NAUCC/48-105 AC G0V7Z8.1
#=GS Q0CJM0_ASPTN/15-72 AC Q0CJM0.1
#=GS G4NH98_MAGO7/18-75 AC G4NH98.1
#=GS DAD1_SCHPO/23-80 AC P87297.2
#=GS F2PHD6_TRIEC/20-77 AC F2PHD6.1
#=GS A3GI56_PICST/23-80 AC A3GI56.1
#=GS C7GLY0_YEAS2/18-75 AC C7GLY0.1
#=GS H6BXV2_EXODN/16-73 AC H6BXV2.1
#=GS G4ZL88_PHYSP/9-66 AC G4ZL88.1
#=GS G2WAC3_YEASK/18-75 AC G2WAC3.1
#=GS C5DPI7_ZYGRC/24-81 AC C5DPI7.1
#=GS A7TJZ6_VANPO/22-79 AC A7TJZ6.1
#=GS E4UXC8_ARTGP/20-77 AC E4UXC8.1
#=GS A7EA52_SCLS1/15-72 AC A7EA52.1
#=GS B4UMY9_CANGA/11-68 AC B4UMY9.1
#=GS G0SYY4_RHOG2/7-64 AC G0SYY4.1
#=GS E6R638_CRYGW/18-75 AC E6R638.1
#=GS G8YEL4_PICSO/6-63 AC G8YEL4.1
#=GS F2R0G5_PICP7/11-68 AC F2R0G5.1
#=GS G9NJL5_HYPAI/19-76 AC G9NJL5.1
#=GS A1DDC0_NEOFI/11-54 AC A1DDC0.1
#=GS F5HHU7_CRYNB/18-75 AC F5HHU7.1
#=GS G2RH58_THITE/17-74 AC G2RH58.1
#=GS D5GMT0_TUBMM/1-36 AC D5GMT0.1
#=GS G0W4K8_NAUDC/20-77 AC G0W4K8.1
#=GS B6JYV4_SCHJY/19-76 AC B6JYV4.1
#=GS B2B1Q0_PODAN/26-83 AC B2B1Q0.1
#=GS F2SI00_TRIRC/20-77 AC F2SI00.1
#=GS B9W9Y9_CANDC/14-71 AC B9W9Y9.1
#=GS Q0UHY2_PHANO/66-123 AC Q0UHY2.2
#=GS DAD1_KLULA/13-70 AC Q6CW48.1
#=GS D8PZQ2_SCHCM/11-68 AC D8PZQ2.1
#=GS C1GZE4_PARBA/35-92 AC C1GZE4.1
#=GS H8X4R9_9ASCO/7-64 AC H8X4R9.1
#=GS A6ZXY0_YEAS7/18-75 AC A6ZXY0.1
#=GS Q4WW14_ASPFU/33-87 AC Q4WW14.1
#=GS B2WGI9_PYRTR/18-75 AC B2WGI9.1
#=GS C5MC33_CANTT/16-73 AC C5MC33.1
#=GS C4R6M6_PICPG/11-68 AC C4R6M6.1
#=GS B8MRD2_TALSN/14-71 AC B8MRD2.1
#=GS B0CVG9_LACBS/7-64 AC B0CVG9.1
#=GS F9FPW2_FUSOF/2224-2267 AC F9FPW2.1
#=GS G8JUV8_ERECY/41-98 AC G8JUV8.1
#=GS H0GSJ4_9SACH/68-125 AC H0GSJ4.1
#=GS G8ZTM6_TORDC/19-76 AC G8ZTM6.1
#=GS H1UXM1_COLHI/21-78 AC H1UXM1.1
#=GS G7E3C7_MIXOS/6-62 AC G7E3C7.1
#=GS G1WZT5_ARTOA/10-67 AC G1WZT5.1
#=GS G0R8H0_HYPJQ/1990-2030 AC G0R8H0.1
#=GS D4APZ5_ARTBC/20-82 AC D4APZ5.1
#=GS G8BF82_CANPC/34-91 AC G8BF82.1
#=GS G4UUD9_NEUT9/19-76 AC G4UUD9.1
#=GS F9XKF9_MYCGM/5-62 AC F9XKF9.1
#=GS E3S8Q2_PYRTT/18-75 AC E3S8Q2.1
#=GS Q2U5J2_ASPOR/15-72 AC Q2U5J2.1
#=GS B6Q1N8_PENMQ/15-72 AC B6Q1N8.1
E3QWE4_COLGM/21-78 ............TYFEQQREELIGEIA.....MSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
E9D5W5_COCPS/11-68 ............SYFEQQRAELLREIS.....LSFEQVLQSINRLNRNLESVI.........AVGNEFSSVEALWSQFENVMAK..................
G4TNY7_PIRID/10-68 ...........a-YFEKEKERHMRRIA.....QTVDEILVTLNAINRSQEITI.........DLARQ-----------------nlgedggamnmwmhlrel
C0NPJ7_AJECG/20-77 ...........t-HFEQQREGLVREIA.....LSLEQVLQNINRLNRNLESVI.........TVGNEFSSVEALWSQFETVM--ga................
G0RYE9_CHATD/18-75 ............SYFEQQRQALIEEIA.....MNFEHVLANINKLNRSLEAVI.........AVGNEFSSVEALWSQFENVMAK..................
B8NL09_ASPFN/15-72 ...........t-VFEQQREELVREIA.....VGMEQVLQNINRLNRNLESIV.........AVGNEFSSVEALWSQFENFM--gr................
F2TUF5_AJEDA/5-54 .....tltkety--------------N.....QSLEQVLQNINRLNRNLESVI.........TVGNEFSSVEALWSQFETVM--g.................
F8MNJ9_NEUT8/19-76 ............TYFEQQREALIGEIA.....NSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
Q8X057_NEUCS/19-76 ............TYFEQQREALIGEIA.....NSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
Q1K5F6_NEUCR/19-76 ............TYFEQQREALIGEIA.....NSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
B3LGP7_YEAS1/18-75 ............KYFIEQRNIVLQEIN.....ETMNSILNGLNGLNISLESSI.........AVGREFQSVSDLWKTLYDGLE-s.................
D6RP18_COPC7/9-66 ............TFFERERDRLSREIT.....SGFEDLLSSTNVLNRKLEEVL.........GMTKEYHTIAALWHSFHELMR-n.................
F0X6T6_GROCL/22-79 ............SYFEQQREILVGEIA.....MSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFEGVMA-k.................
B6HKQ0_PENCW/18-75 ...........t-VFEQQREELVREIA.....VGMEQVLQNMNRLNRNLESVI.........AVGNEFGSVEALWSQFENFM--gr................
DAD1_YARLI/14-71 ............SYFERQRDQYIKNIS.....ASMEDVLNNLNALNRSLEHTV.........GLSQKSEELAEMWSHFYNTVNE..................
G8YC64_PICSO/6-63 ............SYFEKQRDLLIQEIG.....LSLESVIYNLDILNRSLNGAV.........SVGKEFDDVGRLWSHFYDGLNQ..................
C8VKD3_EMENI/13-70 ...........t-VFEEQREELVREIA.....NGMEEVLANINRLSRNLDSVI.........AVGNEFGSVEALWSQFETFM--gr................
G3XNP8_ASPNA/15-72 ...........t-VFEQQRAELVREIA.....VGMEQVLQNINRLNRNLESII.........SVGNEFGSVEALWSQFENFM--gr................
I1RA08_GIBZE/17-74 ............TYFEQQREALLGEIA.....MSFEHVLANINKLNRSLEAVT.........AVGNEFSSVEALWSQFENVMG-k.................
C5DED1_LACTC/20-77 ............KYFIEQREMILQDIG.....QTMDSILNNLNGLNISLENFI.........AVGKEFENVSELWSTFYTGI--sg................
A1CBZ1_ASPCL/11-68 ...........t-VFEQQREELVREIA.....VGMEQVLQNINRLNRNLESII.........AVGNEFSSVEALWSQFENFM--gr................
G8BNL1_TETPH/33-90 ...........e-LFVEKRDILLQDIT.....NTMDSILNSLNGLNISLESSI.........SLGSQFESVCELWKSFYNN---nnn...............
E4ZRA0_LEPMJ/19-76 ............SYYEQQRELLVTEIA.....QSLEIVLQNINKLNRSLEEVT.........QVGSEFAPVESLWSLFENVMAK..................
Q5B9U4_EMENI/13-79 ...........t-VFEEQREELVREIA.....NGMEEVLANINRLSRNLDSVIasrrglimnQVGNEFGSVEALWSQFETFM--gr................
G7XUU5_ASPKW/15-72 ...........t-VFEQQRAELVREIA.....VGMEQVLQNINRLNRNLESII.........SVGNEFGSVEALWSQFENFM--gs................
F7WA01_SORMK/19-70 ............TYFEQQREALVGEIA.....NSFEHVLANINKLNRS---SV.........---TEFSSVEALWSQFENVMAK..................
Q5KG80_CRYNJ/18-75 ............SFFEREKARLIEEIS.....TNFEELMGNMNTLNRTLEQVY.........GVGREFTTVASLWGRFNTLIKE..................
E3K7D7_PUCGT/26-83 ...........s-HFDNQRLKWIAEIS.....ESIGRLYTNLNALNRNIESVN.........LVGRQFENVYNLWSKFEQVI--sv................
DAD1_ASHGO/18-75 ............KYFVEQRDLLLQEIT.....STLDSILNNLNGLNISLENSI.........AVGKEFESVSELWKVFYDGLA-n.................
C9SAI6_VERA1/18-75 ............TYFEQQREVLIGEIA.....MSFEHVLANINKLNRSLEAVT.........AVGNEFSSVEALWSQFENVMAK..................
F4RVG4_MELLP/27-81 ...........s-QFEEEKLKWLAEIF.....ESGGKFFTNINALNRSIESAN.........LVGTQFETVHDLWSKLST----q.................
A5E1R1_LODEL/5-62 ............DYFTKQRDLLLQDIT.....NNLTQVHKNLETLNRSMNESV.........QIGKEFDDVGRLWSVFYDGMNE..................
G9MM21_HYPVG/15-72 ...........a-YFEQQREALIGDIA.....GSFEQVLANINKLNRSLEAII.........AVGNEFSSVEALWSQFENVMAK..................
G3JEJ6_CORMM/17-74 ............SYFEQQREAFLGDIA.....LSFEQVLGNINKLNRSLESII.........AVGNEFSSVETLWSQFENVMG-k.................
C5JUR1_AJEDS/28-84 ............TYFETQREELVREIA.....LSLEQVLQNINRLNRNLESVI.........TVGNEFSSVEALWSQFETVM--g.................
DAD1_YEAST/18-75 ............KYFIEQRNIVLQEIN.....ETMNSILNGLNGLNISLESSI.........AVGREFQSVSDLWKTLYDGLE-s.................
C5FXM8_ARTOC/22-79 ............TYFEEQRAELLREIS.....LSLEGVLQNINKFNRNLESII.........TVGNELSSVEGLWSQFEGVM--gr................
G2QPE8_THIHA/17-74 ............TYFEQQREELIGEIA.....ANFEHVLANINKLNRSLEAVI.........AVGNEFSSVEALWSQFENVMAK..................
E6ZRN1_SPORE/32-89 ...........g-FFERERNRLIQDIS.....KGVESILGNANAVNRKIEESI.........SVGKEFHPISELWSKFERIM--ha................
C4YFV5_CANAW/12-69 ............EYFIKQRDLLIQEIS.....NNLSIVQTNLETLNRSLHESK.........QIGKEFDDVARLWSTFYDGMN-g.................
G3B3Q6_CANTC/2-59 ............SDFEKYRDTLIQEIS.....NSINSIVLNLNTLNRSLHNSI.........QVSKEFDNVSDLWANFYSGLKK..................
DAD1_DEBHA/6-63 ............TYFEKQRDMLIQEIG.....VSIESVVYNLDILNRSLNGSI.........SVGKEFDNVGRLWSHFYDGLNQ..................
F0UNW2_AJEC8/17-68 ..........th--FEQQREGL-----.....-SLEQVLQNINRLNRNLESVI.........TVGNEFSSVEALWSQFETVM--ga................
C5PEN3_COCP7/11-68 ............SYFEQQRAELLREIS.....LSFEQVLQNINRLNRNLESVI.........AVGNEFSSVEALWSQFENVMAK..................
H2AV66_KAZAF/29-86 ............KYFLEQRNVILQDIN.....NTMDSILNGLNELNISLENSI.........AVGKEFESISLLWKNFYNELEE..................
G2WWM7_VERDV/528-585 ............TYFEQQREVLIGEIA.....MSFEHVLANINKLNRSLEAVT.........AVGNEFSSVEALWSQFENVMAK..................
I1BIU5_RHIO9/5-62 ...........s-EFEQQFTKLLKDAA.....KGLEDLQSQFEDMDRNLQTVH.........SLGKQVYESSHLWHEFNKAI--dn................
G3ANX2_SPAPN/17-74 ............SDFEKQRSLLIQQIA.....NELSNLNTNIETLNRVFDQSL.........SIGKEFDDLGRLWSKFYAGVD-e.................
B0Y296_ASPFC/33-87 dktqkslhhatv---------------.....QGMEQVLQNINRLNRNLESII.........AVGNEFSSVEALWSQFENFMD-r.................
C5GMU6_AJEDR/26-82 ............TYFETQREELVREIA.....LSLEQVLQNINRLNRNLESVI.........TVGNEFSSVEALWSQFETVM--g.................
Q2GV97_CHAGB/44-88 ..........ne---------------.....QSFEHVLANINKLNRSLEAVI.........AVGNEFSSVEALWSQFENVMAK..................
C8Z4T6_YEAS8/18-75 ............KYFIEQRNIVLQEIN.....ETMNSILNGLNGLNISLESSI.........AVGREFQSVSDLWKTLYDGLE-s.................
G0V7Z8_NAUCC/48-105 ...........k-KFIAQRDLILQEIT.....VTMDSILNGLNELNISLESSI.........AVGKEFESVADLWKTFYDGLE-s.................
Q0CJM0_ASPTN/15-72 ...........t-VFEQQREELVREIA.....VGMEQVLQNINRLNRNLESII.........SVGNEFSSVEALWSQFENFM--gr................
G4NH98_MAGO7/18-75 ..........tp--FEQQREALIGEIA.....MSFEQVLANMNKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
DAD1_SCHPO/23-80 ...........i-DFERRRRLLTLQIS.....KSMNEVVNLMSALNKNLESIN.........GVGKEFENVASLWKEFQNSVL-q.................
F2PHD6_TRIEC/20-77 ............TYFEEQRAELLREIS.....LSLEGVLQNINKFNRNLESII.........TVGNELSSVEGLWSQFEGVM--gr................
A3GI56_PICST/23-80 ............SNFEKQRDLLIQEIS.....NNIDTVVYNLDILNRSLNESI.........QVGKEFDDVGRLWSNFYDGMNQ..................
C7GLY0_YEAS2/18-75 ............KYFIEQRNIVLQEIN.....ETMNSILNGLNGLNISLESSI.........AVGREFQSVSDLWKTLYDGLE-s.................
H6BXV2_EXODN/16-73 ...........s-EFEIRRAALVGEIG.....ESLEQVLAQINALNRSLEGII.........EIGNEFSSVESLWSQFEKVM--gr................
G4ZL88_PHYSP/9-66 ...........e-WFQKEKKRLEDEIR.....EEMQEAVSNVHILNQNMEHLN.........DVGQEVVAISSGWVQFLRQM--ta................
G2WAC3_YEASK/18-75 ............KYFIEQRNIVLQEIN.....DTMNSILNGLNGLNISLESSI.........AVGREFQSVSDLWKTLYDGLE-s.................
C5DPI7_ZYGRC/24-81 ............KYFIEQRDLVLQDIN.....NTMDSILNNLNSLNISLENSI.........AVGKEFESVAELWKTFYNGLE-g.................
A7TJZ6_VANPO/22-79 ...........q-LFMEKRDLILQDIT.....NTMDSILNNLNGLNISLESSI.........ALGSQFESVCDLWKTFYTSAP-k.................
E4UXC8_ARTGP/20-77 ............TYFEEQRAELLREIS.....LSLEGVLQNINKFNRNLESII.........TVGNEMSSVEGLWSQFEGVM--gr................
A7EA52_SCLS1/15-72 ............SYFEQQREILLGEIA.....VSFEHVLSSINKLNRSLEGVI.........AVGNEFSSVEALWSQFENVMAK..................
B4UMY9_CANGA/11-68 ............KDFIEQRDVLLQEVN.....ELVASILNGLNDLNISLESSI.........SVGKEFEKVSTLWKSFYDGLE-s.................
G0SYY4_RHOG2/7-64 ............SDFERERDRLIAEIA.....ENLGKCVTAVNQLNRNIENVT.........QVGGGFDAVHHLWASFQQVMA-n.................
E6R638_CRYGW/18-75 ............SFFEREKARLIEEIS.....TNFEELMGNMNTLNRTLEQVY.........GVGREFTTVASLWGRFNTLIKE..................
G8YEL4_PICSO/6-63 ............SYFEKQRDLLIQEIG.....LSLESVIYNLDILNRSLNGAV.........SVGKEFDDVGRLWSHFYDGLNQ..................
F2R0G5_PICP7/11-68 ............SYFEKQRDALVAEIS.....VSMDTLLNNVNTLNRSLEGAI.........AVGKEFDNVAAIWNNFYDGMDQ..................
G9NJL5_HYPAI/19-76 ...........a-YFEQQREVLIGDIA.....ESFEQVLSSINKLNRSLEAVI.........AVGNEFSSVEALWSQFENVMAK..................
A1DDC0_NEOFI/11-54 ...........t-VFEQQRAELVREIA.....VGMEQVLQNINRLNRNLESII.........AVSS------------------ietn..............
F5HHU7_CRYNB/18-75 ............SFFEREKARLIEEIS.....TNFEELMGNMNTLNRTLEQVY.........GVGREFTTVASLWGRFNTLIKE..................
G2RH58_THITE/17-74 ............TYFEQQREELIGEIA.....MSFEHVLANINKLNRSLEAVI.........AVGNEFSSVEALWSQFENVMAK..................
D5GMT0_TUBMM/1-36 ...........m---------------.....--------NMNLLNRSLEGVV.........AVGREFESVEALWSQFEGVM--gk................
G0W4K8_NAUDC/20-77 ...........r-QFIEQRDLILQEIN.....VTMDSILNGLNELNISLESSI.........AVGKGFESVSELWKTFFDGLE-s.................
B6JYV4_SCHJY/19-76 ...........s-TFERKRRQLILQIS.....NNMHEIVNLLDVLNKNLESVN.........GVGKEFDKVASLWMSFHESVT-n.................
B2B1Q0_PODAN/26-83 ............TYFELQREELVSEIA.....MSFEHVLANINKLNRSLEAVI.........AVGNEFSSVEALWSTFENVMAK..................
F2SI00_TRIRC/20-77 ...........t-CFEEQRAELLREIS.....LSLEGVLQNINKFNRNLESII.........TVGNELSSVEGLWSQFEGVM--gr................
B9W9Y9_CANDC/14-71 ............EYFIKQRDLLIQEIS.....NNLTKIHTNLETLNRSLHESK.........QIGKEFDDVARLWSTFYDGMN-r.................
Q0UHY2_PHANO/66-123 ............TYFEQQREMLVTEIA.....QSLELVLQNINKLNRSLEEVT.........QVGNEFAPVESLWSHFENVMAK..................
DAD1_KLULA/13-70 ............KYFIEQRSLILQEIN.....ESMDAILNQLNGLNITLENSI.........AVGKEFENVSQIWKLFYNGLE-s.................
D8PZQ2_SCHCM/11-68 ............SFFTRERERLSREIA.....ISLESLLSSTNGLNRHLEEAL.........GMTKEYDTVAALWGAFHEMM--rg................
C1GZE4_PARBA/35-92 ............TYFEQQREELVREIA.....LSLEQVLQNINSLNRNLESVI.........TVGNEFSSVEALWSQFETVM--gs................
H8X4R9_9ASCO/7-64 ............DYFNKQRDILIQEIS.....NNLSEVFTNLETLNRSLSESI.........QIGKEFDDVGRLWRTFYDGMNK..................
A6ZXY0_YEAS7/18-75 ............KYFIEQRNIVLQEIN.....ETMNSILNGLNGLNISLESSI.........AVGREFQSVSDLWKTLYDGLE-s.................
Q4WW14_ASPFU/33-87 dktqkslhhatv---------------.....QGMEQVLQNINRLNRNLESII.........AVGNEFSSVEALWSQFENFMD-r.................
B2WGI9_PYRTR/18-75 ............SYYEQQREMLVTEIA.....QSLEVVLQNINKLNRSLEEVT.........SVGNEFAPVESLWSHFENVMAK..................
C5MC33_CANTT/16-73 ............EYFIKQRDLLIQEIS.....NNLTKVHTNLEALNRSLHESK.........QIGKEFDDVARLWSTFYDGMNQ..................
C4R6M6_PICPG/11-68 ............SYFEKQRDALVAEIS.....VSMDTLLNNVNTLNRSLEGAI.........AVGKEFDNVAAIWNNFYDGMDQ..................
B8MRD2_TALSN/14-71 ...........t-EFEIQRSELVREIA.....LGMESVLQYINRLNRNLESII.........AVGNEFSSVEALWSHFENVM--gs................
B0CVG9_LACBS/7-64 ............SFFERERDRLSREIT.....SGFEELLSSTNVLNRKLEEVL.........GMSKEYTTIASLWHTFHRLMQ-n.................
F9FPW2_FUSOF/2224-2267 ...........l---------------.....KSFEHVLANINKLNRSLEAVT.........AVGNEFSSVEALWSQFENVMD-k.................
G8JUV8_ERECY/41-98 ............KYFMEQRDLLLQDIN.....NTTDSILNHLNGLNISLENSI.........AVGKEFESVSELWKLFYDGLA-n.................
H0GSJ4_9SACH/68-125 ............KYFIEQRNIVLQEID.....ETMSSILNGLNVLNISLESSI.........AVGREFQSVSDLWKTFYDGLE-s.................
G8ZTM6_TORDC/19-76 ............KYFIEQRDLIVQDIN.....NTMDSILNNLNTLNISLENSI.........AVGKEFESVSDLWKTFYNGLE-s.................
H1UXM1_COLHI/21-78 ............TYFEQQREELLGEIA.....MSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
G7E3C7_MIXOS/6-62 ...........a--YEAERERLIRLIS.....ENLGRTLTSFNTLNRSVEAVT.........LVGNQFESVTTLWQQFEDTMA-h.................
G1WZT5_ARTOA/10-67 ............TYFETQREALIEEIC.....KSFDQVLLNLNHLNRSLEGLA.........GVGQEFTEIEALWSKFDTVMSQ..................
G0R8H0_HYPJQ/1990-2030 ...........a-YFEQQREALIGDIA.....ESFEHVLANINKLNRSLEAVI.........A---------------------keer..............
D4APZ5_ARTBC/20-82 ............SYFEEQRAELLREISlwwgdKSLEGVLQNINKFNRNLESII.........TVGNELSSVEGLWSQFEGVM--dr................
G8BF82_CANPC/34-91 ............DYFNKQRDLLIQEIT.....NNLTEVYTNLETLNRSLSESI.........QIGKEFDDVGRLWRTFYDGMNK..................
G4UUD9_NEUT9/19-76 ............TYFEQQREALIGEIA.....NSFEHVLANINKLNRSLEAVI.........TVGNEFSSVEALWSQFENVMAK..................
F9XKF9_MYCGM/5-62 ............TYFEQQRQLLIGDVA.....ASLENVLQNINKLNRSLEGVI.........AVGNEFSQVEGLWSQFENVMAK..................
E3S8Q2_PYRTT/18-75 ............SYYEQQREMLVTEIA.....QSLEVVLQNINKLNRSLEEVT.........SVGNEFAPVESLWSHFENVMAK..................
Q2U5J2_ASPOR/15-72 ...........t-VFEQQREELVREIA.....VGMEQVLQNINRLNRNLESIV.........AVGNEFSSVEALWSQFENFM--gr................
B6Q1N8_PENMQ/15-72 ...........s-EFESQRSELVREIA.....LGMESVLQYINRLNRNLESII.........AVGNEFSSVEALWSQFENVM--gs................
#=GC seq_cons ............paFEpQR-hLlpEIu.....tohEpVLsNlNpLNRSLEulI.........uVGpEFsSVpuLWSpFpssMt.t.................
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