GenomeNet

Database: Pfam
Entry: DASH_Dam1
LinkDB: DASH_Dam1
Original site: DASH_Dam1 
#=GF ID   DASH_Dam1
#=GF AC   PF08653.7
#=GF DE   DASH complex subunit Dam1
#=GF AU   Wood V, Finn RD
#=GF SE   Manual
#=GF GA   26.60 26.60;
#=GF TC   26.70 29.00;
#=GF NC   25.30 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11799062
#=GF RT   The mitotic spindle is required for loading of the DASH complex
#=GF RT   onto the kinetochore. 
#=GF RA   Li Y, Bachant J, Alcasabas AA, Wang Y, Qin J, Elledge SJ; 
#=GF RL   Genes Dev 2002;16:183-197.
#=GF RN   [2]
#=GF RM   15640796
#=GF RT   The yeast DASH complex forms closed rings on microtubules. 
#=GF RA   Miranda JJ, De Wulf P, Sorger PK, Harrison SC; 
#=GF RL   Nat Struct Mol Biol. 2005;12:138-143.
#=GF RN   [3]
#=GF RM   15664196
#=GF RT   Formation of a dynamic kinetochore- microtubule interface
#=GF RT   through assembly of the Dam1 ring complex. 
#=GF RA   Westermann S, Avila-Sakar A, Wang HW, Niederstrasser H, Wong J,
#=GF RA   Drubin DG, Nogales E, Barnes G; 
#=GF RL   Mol Cell. 2005;17:277-290.
#=GF RN   [4]
#=GF RM   15632076
#=GF RT   Genetic analysis of the kinetochore DASH complex reveals an
#=GF RT   antagonistic relationship with the ras/protein kinase A pathway
#=GF RT   and a novel subunit required for Ask1 association. 
#=GF RA   Li JM, Li Y, Elledge SJ; 
#=GF RL   Mol Cell Biol. 2005;25:767-778.
#=GF DR   INTERPRO; IPR013962;
#=GF CC   The DASH complex is a ~10 subunit microtubule-binding complex
#=GF CC   that is transferred to the kinetochore prior to mitosis [1]. In
#=GF CC   Saccharomyces cerevisiae DASH forms both rings and spiral
#=GF CC   structures on microtubules in vitro [2,3].  Components of the
#=GF CC   DASH complex, including Dam1, Duo1, Spc34, Dad1 and Ask1, are
#=GF CC   essential and connect the centromere to the plus end of spindle
#=GF CC   microtubules [4]. 
#=GF SQ   184
#=GS DAM1_YEAST/63-118         AC P53267.2
#=GS A0A0C4F088_PUCT1/62-117   AC A0A0C4F088.1
#=GS S7PU00_GLOTA/40-95        AC S7PU00.1
#=GS C5GVH7_AJEDR/54-109       AC C5GVH7.1
#=GS DAM1_CANAL/54-110         AC Q5APC8.1
#=GS Q4WLQ4_ASPFU/53-108       AC Q4WLQ4.2
#=GS C4YD67_CANAW/54-110       AC C4YD67.1
#=GS G8ZX10_TORDC/65-119       AC G8ZX10.1
#=GS E2L4H3_MONPE/19-64        AC E2L4H3.1
#=GS Q2GQL1_CHAGB/96-151       AC Q2GQL1.1
#=GS D0N6S4_PHYIT/5-61         AC D0N6S4.1
#=GS B8MAN5_TALSN/52-107       AC B8MAN5.1
#=GS N1PDZ2_DOTSN/66-121       AC N1PDZ2.1
#=GS G3YFV1_ASPNA/52-107       AC G3YFV1.1
#=GS V2XUK4_MONRO/45-100       AC V2XUK4.1
#=GS G2WVJ3_VERDV/54-109       AC G2WVJ3.1
#=GS G0VF94_NAUCC/66-121       AC G0VF94.1
#=GS G0WDM1_NAUDC/96-151       AC G0WDM1.2
#=GS I4Y769_WALSC/41-96        AC I4Y769.1
#=GS B6QDL7_PENMQ/53-108       AC B6QDL7.1
#=GS H1UY82_COLHI/64-119       AC H1UY82.1
#=GS K3WZD0_PYTUL/4-58         AC K3WZD0.1
#=GS R0K9Z2_SETT2/1-45         AC R0K9Z2.1
#=GS A0A0C4DV55_MAGP6/41-96    AC A0A0C4DV55.1
#=GS D5GDP7_TUBMM/165-220      AC D5GDP7.1
#=GS T5AB46_OPHSC/51-106       AC T5AB46.1
#=GS A2QLN9_ASPNC/52-106       AC A2QLN9.1
#=GS I2H1D5_TETBL/59-113       AC I2H1D5.1
#=GS K1V9Z2_TRIAC/34-89        AC K1V9Z2.1
#=GS DAM1_SCHPO/33-88          AC Q9HDZ6.1
#=GS M2UTS7_COCH5/56-111       AC M2UTS7.1
#=GS G0RKG2_HYPJQ/57-111       AC G0RKG2.1
#=GS C5DJ70_LACTC/57-112       AC C5DJ70.1
#=GS F9FCG1_FUSOF/147-202      AC F9FCG1.1
#=GS I2FRX8_USTH4/45-100       AC I2FRX8.1
#=GS G2R835_THITE/55-110       AC G2R835.1
#=GS M5E8R1_MALS4/41-94        AC M5E8R1.1
#=GS C1H2M8_PARBA/54-109       AC C1H2M8.2
#=GS U4L9K3_PYROM/48-103       AC U4L9K3.1
#=GS G7XLZ6_ASPKW/52-107       AC G7XLZ6.1
#=GS F0U7X4_AJEC8/54-109       AC F0U7X4.1
#=GS J6EFB3_SACK1/63-118       AC J6EFB3.1
#=GS A3LPT1_PICST/53-109       AC A3LPT1.2
#=GS G4YX47_PHYSP/5-60         AC G4YX47.1
#=GS V5ET67_PSEBG/45-100       AC V5ET67.1
#=GS A0A066XA16_COLSU/60-115   AC A0A066XA16.1
#=GS M2REL9_CERS8/39-94        AC M2REL9.1
#=GS S3DHC0_GLAL2/57-112       AC S3DHC0.1
#=GS F4RB82_MELLP/56-111       AC F4RB82.1
#=GS A5DEJ5_PICGU/53-109       AC A5DEJ5.2
#=GS A1CUB1_ASPCL/53-108       AC A1CUB1.1
#=GS G8BT71_TETPH/89-144       AC G8BT71.1
#=GS E7QF33_YEASZ/63-118       AC E7QF33.1
#=GS S0DYD3_GIBF5/52-107       AC S0DYD3.1
#=GS J7S376_KAZNA/63-118       AC J7S376.1
#=GS S2JFN3_MUCC1/21-75        AC S2JFN3.1
#=GS C4YCC2_CLAL4/46-102       AC C4YCC2.1
#=GS E3QI09_COLGM/60-115       AC E3QI09.1
#=GS S6EAJ0_ZYGB2/66-120       AC S6EAJ0.1
#=GS F2SFC1_TRIRC/54-109       AC F2SFC1.2
#=GS B6K035_SCHJY/29-84        AC B6K035.1
#=GS A5DSM3_LODEL/58-114       AC A5DSM3.1
#=GS M1W2F8_CLAP2/52-107       AC M1W2F8.1
#=GS Q7S3H5_NEUCR/54-109       AC Q7S3H5.1
#=GS U1HUF7_ENDPU/52-107       AC U1HUF7.1
#=GS I1BI76_RHIO9/32-86        AC I1BI76.1
#=GS M7WPB2_RHOT1/61-116       AC M7WPB2.1
#=GS E6ZYV2_SPORE/45-100       AC E6ZYV2.1
#=GS J3NWS8_GAGT3/58-113       AC J3NWS8.1
#=GS C5DT85_ZYGRC/66-120       AC C5DT85.1
#=GS K5W7Y2_PHACS/39-94        AC K5W7Y2.1
#=GS A6R6I2_AJECN/54-109       AC A6R6I2.1
#=GS C4R6Y1_PICPG/59-113       AC C4R6Y1.1
#=GS K2S1M9_MACPH/69-124       AC K2S1M9.1
#=GS J4H4C4_FIBRA/40-95        AC J4H4C4.1
#=GS M7T642_EUTLA/68-122       AC M7T642.1
#=GS B8PD84_POSPM/39-93        AC B8PD84.1
#=GS Q0CSM7_ASPTN/54-108       AC Q0CSM7.1
#=GS A0A099P7A6_ISSOR/104-154  AC A0A099P7A6.1
#=GS V5HTZ3_BYSSN/52-107       AC V5HTZ3.1
#=GS A0A0A2K499_PENEN/51-106   AC A0A0A2K499.1
#=GS M3K4E2_CANMX/53-109       AC M3K4E2.1
#=GS F7W3H4_SORMK/54-109       AC F7W3H4.1
#=GS D8PU57_SCHCM/37-91        AC D8PU57.1
#=GS G8BA67_CANPC/51-107       AC G8BA67.1
#=GS I1BI98_RHIO9/32-87        AC I1BI98.1
#=GS G9N1S4_HYPVG/45-100       AC G9N1S4.1
#=GS C7ZLR9_NECH7/32-85        AC C7ZLR9.1
#=GS Q2ULJ4_ASPOR/54-109       AC Q2ULJ4.1
#=GS A8Q3E8_MALGO/39-93        AC A8Q3E8.1
#=GS G8JN32_ERECY/62-117       AC G8JN32.1
#=GS G1X6V6_ARTOA/52-107       AC G1X6V6.1
#=GS G0S2K4_CHATD/55-110       AC G0S2K4.1
#=GS E9CVH2_COCPS/52-107       AC E9CVH2.1
#=GS R8BRL2_TOGMI/57-112       AC R8BRL2.1
#=GS G4TG26_PIRID/44-99        AC G4TG26.1
#=GS R9ADW5_WALI9/37-92        AC R9ADW5.1
#=GS A7F0C8_SCLS1/59-114       AC A7F0C8.1
#=GS C6H6P0_AJECH/54-109       AC C6H6P0.1
#=GS W7N0W4_GIBM7/52-107       AC W7N0W4.1
#=GS B2VXI5_PYRTR/56-111       AC B2VXI5.1
#=GS R9P4H5_PSEHS/1-52         AC R9P4H5.1
#=GS G4UXD7_NEUT9/54-109       AC G4UXD7.1
#=GS L0PCG7_PNEJ8/39-94        AC L0PCG7.1
#=GS G3J3K5_CORMM/53-108       AC G3J3K5.1
#=GS A0A016PWZ0_GIBZA/52-107   AC A0A016PWZ0.1
#=GS M3AK27_PSEFD/66-121       AC M3AK27.1
#=GS R4XFP9_TAPDE/43-98        AC R4XFP9.1
#=GS A0A0D1CUN2_USTMA/45-100   AC A0A0D1CUN2.1
#=GS M7UHC9_BOTF1/59-114       AC M7UHC9.1
#=GS F2PYX3_TRIEC/53-108       AC F2PYX3.1
#=GS E3KJ10_PUCGT/62-117       AC E3KJ10.1
#=GS G8YGT2_PICSO/62-118       AC G8YGT2.1
#=GS G9PA35_HYPAI/56-110       AC G9PA35.1
#=GS B0DBU2_LACBS/30-83        AC B0DBU2.1
#=GS K0KG33_WICCF/41-95        AC K0KG33.1
#=GS A0A0A2L9X3_PENIT/51-106   AC A0A0A2L9X3.1
#=GS C0NH88_AJECG/54-109       AC C0NH88.1
#=GS E9EWP8_METRA/61-116       AC E9EWP8.1
#=GS H2AS78_KAZAF/56-111       AC H2AS78.1
#=GS S7ZR90_PENO1/53-108       AC S7ZR90.1
#=GS U5HCP9_USTV1/55-110       AC U5HCP9.1
#=GS C1GB70_PARBD/54-109       AC C1GB70.1
#=GS S9W4D3_SCHCR/28-88        AC S9W4D3.1
#=GS Q0U873_PHANO/103-157      AC Q0U873.1
#=GS A0A0D2XIG2_FUSO4/52-107   AC A0A0D2XIG2.1
#=GS G3ATN1_SPAPN/43-99        AC G3ATN1.1
#=GS S8FC91_FOMPI/39-93        AC S8FC91.1
#=GS W1Q780_OGAPD/96-148       AC W1Q780.1
#=GS A0A0B1PE61_UNCNE/59-114   AC A0A0B1PE61.1
#=GS M2THS3_COCSN/56-111       AC M2THS3.1
#=GS L8G5D6_PSED2/57-112       AC L8G5D6.1
#=GS M4BGH6_HYAAE/5-59         AC M4BGH6.1
#=GS DAM1_YARLI/33-88          AC Q6C2T8.1
#=GS E9DVN1_METAQ/59-113       AC E9DVN1.1
#=GS A8NC24_COPC7/1-51         AC A8NC24.1
#=GS K5VSJ3_AGABU/39-94        AC K5VSJ3.1
#=GS A0A0E1S567_COCIM/52-107   AC A0A0E1S567.1
#=GS B8PEV3_POSPM/29-83        AC B8PEV3.1
#=GS A0A099NSU4_ISSOR/34-83    AC A0A099NSU4.1
#=GS C8V7J7_EMENI/52-107       AC C8V7J7.1
#=GS DAM1_DEBHA/54-110         AC Q6BWK6.2
#=GS N4U0Z8_FUSC1/52-107       AC N4U0Z8.1
#=GS E7LU88_YEASV/63-118       AC E7LU88.1
#=GS A0A060SKK8_PYCCI/37-78    AC A0A060SKK8.1
#=GS B2AKR3_PODAN/63-118       AC B2AKR3.1
#=GS G3BCW7_CANTC/48-104       AC G3BCW7.1
#=GS M9MC12_PSEA3/45-100       AC M9MC12.1
#=GS C5MBE3_CANTT/55-111       AC C5MBE3.1
#=GS K9FW94_PEND2/51-106       AC K9FW94.1
#=GS DAM1_CANGA/54-109         AC Q6FLB2.1
#=GS A0A067CQR5_SAPPC/5-58     AC A0A067CQR5.1
#=GS M3AU07_SPHMS/1-45         AC M3AU07.1
#=GS E5QZ96_ARTGP/53-108       AC E5QZ96.1
#=GS R1EKR8_BOTPV/69-124       AC R1EKR8.1
#=GS S3BTL9_OPHP1/54-109       AC S3BTL9.1
#=GS U9T2I6_RHIID/44-99        AC U9T2I6.1
#=GS A7TEY5_VANPO/70-125       AC A7TEY5.1
#=GS E7KNS6_YEASL/63-118       AC E7KNS6.1
#=GS K1X003_MARBU/50-105       AC K1X003.1
#=GS E3RNH1_PYRTT/56-111       AC E3RNH1.1
#=GS B6HPL0_PENCW/51-105       AC B6HPL0.1
#=GS C5FL19_ARTOC/48-103       AC C5FL19.1
#=GS DAM1_ASHGO/62-117         AC Q75EQ0.2
#=GS L8WZ01_THACA/36-91        AC L8WZ01.1
#=GS S8CA78_DACHA/52-107       AC S8CA78.1
#=GS M7PDN8_PNEMU/39-94        AC M7PDN8.1
#=GS G4NDS4_MAGO7/57-112       AC G4NDS4.1
#=GS N1J916_BLUG1/58-113       AC N1J916.1
#=GS G7E6Q5_MIXOS/40-95        AC G7E6Q5.1
#=GS F0XEH0_GROCL/54-109       AC F0XEH0.1
#=GS G2QJY2_THIHA/51-106       AC G2QJY2.1
#=GS DAM1_KLULA/50-104         AC Q6CVK1.1
#=GS H6C1X1_EXODN/54-109       AC H6C1X1.1
#=GS M5FZ72_DACSP/40-95        AC M5FZ72.1
#=GS E5A323_LEPMJ/56-110       AC E5A323.1
#=GS K3VWI8_FUSPC/52-107       AC K3VWI8.1
#=GS L2FFX5_COLGN/52-106       AC L2FFX5.1
#=GS T0KFL8_COLGC/110-165      AC T0KFL8.1
#=GS N4VN04_COLOR/49-104       AC N4VN04.1
#=GS R7YYN5_CONA1/59-114       AC R7YYN5.1
#=GS B8N236_ASPFN/54-109       AC B8N236.1
#=GS N1RMT8_FUSC4/52-107       AC N1RMT8.1
#=GS C9SRA7_VERA1/54-109       AC C9SRA7.1
DAM1_YEAST/63-118                    .......LLPKIRELSDSIITLDSNFTRLNFIHESLAD.LNESLGSLLYGIMSNSWCVEFSQAP...
A0A0C4F088_PUCT1/62-117              .......LAPLFVDLSDAITDLHINLSNLDLVCQDLDG.FNEAFSAFIYGLRVNSYVTDFEEAP...
S7PU00_GLOTA/40-95                   .......LEPAMSELLDEAEALQANVEGLKGLSESLET.FNEAFASYLYMMTMNSLTVDWPQEP...
C5GVH7_AJEDR/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPEAP...
DAM1_CANAL/54-110                    ......i-VEKFASLAESMETLDLHMHDLCHIHDHISNqFNESFASFLYGLSMTMWCVDFPGCP...
Q4WLQ4_ASPFU/53-108                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
C4YD67_CANAW/54-110                  ......i-VEKFASLAESMETLDLHMHDLCHIHDHISNqFNESFASFLYGLSMTMWCVDFPGCP...
G8ZX10_TORDC/65-119                  ......i-LPQIRELSDSIITLDANFTQLNFIHESLVD.FNESLGALLYGLMCNSWCVDFPS--v..
E2L4H3_MONPE/19-64                   ..rstpy---------------QANVEGMKRLSDSLGT.FNESFASWLYIMDMNALTTDWPQAP...
Q2GQL1_CHAGB/96-151                  ......f-EPAFAELSDAVADLEANMMHFQLMHESLSR.FSESFASFLYGLNMNAFCVDFPEGP...
D0N6S4_PHYIT/5-61                    .....ll--SPFAELCGALRGLQEQVEQLSRVHDAVDD.FNSAFGAFQGAMALHASCLTYPK--nap
B8MAN5_TALSN/52-107                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FSESFASFLYGLNMNAFCVDFPEAP...
N1PDZ2_DOTSN/66-121                  .......LEPAFGEFSDAMADLEANMMHLQLLNESIGR.FNENFGAFLYGMNMSAFCVDFPEAP...
G3YFV1_ASPNA/52-107                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
V2XUK4_MONRO/45-100                  .......LGPAMSEFTDEIDTLQANVEGMKRLSDSLGT.FNESFASWLYIMDMNALTTDWPQAP...
G2WVJ3_VERDV/54-109                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLSR.FSESFASFLYGLNMNAFCVDFPEGP...
G0VF94_NAUCC/66-121                  .......LLPQIQELTDSMITLDGNLTRLNFIHESLVD.LNESIGSLLYGLMCNSWCVEFPNVP...
G0WDM1_NAUDC/96-151                  .......LLPQIQELTESMVTLDTNFTRLNFIHESLVD.LNESVGSLLYGLMCNSWCVEFPNVP...
I4Y769_WALSC/41-96                   .......LTPALSDLSDELDGILSSTHQMVELDKALAD.FNHGFGSLLWALKLNAYCVNWPEAP...
B6QDL7_PENMQ/53-108                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FSESFASFLYGLNMNAFCVDFPEAP...
H1UY82_COLHI/64-119                  ......f-EPAFAELSDAVADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFQEGP...
K3WZD0_PYTUL/4-58                    .......LTEPFADLCHALRSMRGQVQELVKVHESIDA.FNAAFGAFQTAMALHASCLEFP---ap.
R0K9Z2_SETT2/1-45                    .......-----------MADLEQNFVQLQLMHESLAR.FSESFAAFLYGMNMNAFCVDFPEAP...
A0A0C4DV55_MAGP6/41-96               ......f-EPAFAELADAMADLEANMMHFQIMHESLSR.FSESFASFLYGVNMNAFCVEFPEAP...
D5GDP7_TUBMM/165-220                 .......LEPAFAELSDAVTTLEVNMADMQIMHDSLSR.FSESFASFLYGLNMNAFCVDFTEAP...
T5AB46_OPHSC/51-106                  ......f-EPAFAELTDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
A2QLN9_ASPNC/52-106                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPE--d..
I2H1D5_TETBL/59-113                  ......v-VPQIRILNESMITLDSNFQRLNSINESLVS.FNESFGSLLYGLMCNAWCVEYPE--n..
K1V9Z2_TRIAC/34-89                   .......LAPALQDLADEVAALSTNTQRISALHDALGQ.FNEGFAAYLYALKMNAFCVEWPQAP...
DAM1_SCHPO/33-88                     ......f-TKSLAVLDDNVSEFRKRMNHLSATKQILDN.FNESFSSFLYGLQINAFCVDYENAP...
M2UTS7_COCH5/56-111                  .......LQDGFAELSDAMADLEQNFVHLQLMHESLAR.FSESFAAFLYGMNMNAFCVDFPEAP...
G0RKG2_HYPJQ/57-111                  .......LEPMFAELSDSMADLEANMMHFQLIDESLAR.FGESFASFLYGLNMNAFCVDFPEV-...
C5DJ70_LACTC/57-112                  .......LLPQVRELSDAMITLDSNFTQMNFIHESLVD.LNESVSALLYGLMCNSWCVDFPNMP...
F9FCG1_FUSOF/147-202                 ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
I2FRX8_USTH4/45-100                  .......LQGAMTDLAEEVGVLKLNLENVEAVHESLHS.FNENFAMYIYGLKMNAYCVEWPEAP...
G2R835_THITE/55-110                  ......f-EPAFAELSDAVADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
M5E8R1_MALS4/41-94                   .....de---ALPILAEETAALHANLADMADIHQSLST.FNESFAAFLYGIKMNAFCVEWPE--y..
C1H2M8_PARBA/54-109                  .......LEPQFAELADSMADLEANFMYLQLMHESLSR.FNECFASFLYGLNMNAFCVDFPEAP...
U4L9K3_PYROM/48-103                  ......m-ASKFEELSIETETFESHLDDLKIMHNSINR.FNENFASFLYGLNMNAFCIGFSEAP...
G7XLZ6_ASPKW/52-107                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
F0U7X4_AJEC8/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FNENFASFLYGLNMNAFCVDFPEAP...
J6EFB3_SACK1/63-118                  .......LLPKIRELSDSIITLDSNFTHLNFIHESLAD.LNESLGSLLYGIMSNSWCVEFSQAP...
A3LPT1_PICST/53-109                  ......n-TEKFERLSDSLEELDANMNNLSSIHDAISNqFNEPFASFLYGISMTMWCVDFPGCP...
G4YX47_PHYSP/5-60                    ....liv---PFAELCGALRGLQEQVEQLSRVHEAVDD.FNSAFGAFQGAMALHASCLTYPKTP...
V5ET67_PSEBG/45-100                  .......LQGAMTDLAEEVGVLQLNLENIEAVHESLHS.FNENFAMYIYGLKMNAYCVEWPEAP...
A0A066XA16_COLSU/60-115              ......f-EPAFAELSDAVADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFQEGP...
M2REL9_CERS8/39-94                   .......LEPAMSELVDEAESLNTNVSGLKNLGDALTT.FNESFASLLYVMNMNALTTDWPQAP...
S3DHC0_GLAL2/57-112                  ......f-EPAFAELSDSMADLEANFMHLQLMHESLAR.FSENFASFLYGLNMNAFCVDFPEAP...
F4RB82_MELLP/56-111                  ......i-SPLFSDLSDSIQDLHTNLIRLDQVCENLNG.FNQSFSSYLYGLRMIYYTTDFDEAP...
A5DEJ5_PICGU/53-109                  .....nr--DRFGQLSDAMEELDVNMTNLQQIHEAMSGgFNESFAAFLYGLNITTWCVDFPGCP...
A1CUB1_ASPCL/53-108                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
G8BT71_TETPH/89-144                  .......LLPSIRSLNDSMNTLDKNFSDLNIIQENLID.FNESLSALLYGMMFNSWCVAYPSIP...
E7QF33_YEASZ/63-118                  .......LLPKIRELSDSIITLDSNFTRLNFIHESLAD.LNESLGSLLYGIMSNSWCVEFSQAP...
S0DYD3_GIBF5/52-107                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
J7S376_KAZNA/63-118                  .......LRPQLNDLHDSVVTMDDNFLRLNNIHENLVD.LNESFGSLLYGIIVNSACINFAGFP...
S2JFN3_MUCC1/21-75                   ......l-IPPIEKLSDCFNGLHRQFDKLKQVNDNLVE.FNDSFSAFLFGLAANDTTVKWR---sl.
C4YCC2_CLAL4/46-102                  .....ni--ERFEAVADAVKELESNMTDLAQMHAAVNGgFNEPFAAFLYGLLITMFCNNFPGCP...
E3QI09_COLGM/60-115                  ......f-EPAFAELSDAVADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFQEGP...
S6EAJ0_ZYGB2/66-120                  ......i-LPQIREFSDSMITLDANFTQLNFIHESLVD.FNESLGSLLYGLMCNSWCVDFPH--v..
F2SFC1_TRIRC/54-109                  .......LEPQFAELADSMADLEENFVHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPETP...
B6K035_SCHJY/29-84                   ......l-VDPLQVLCERLDEFRERVDQLSQTRKNLVS.FNEAFSSLLYGLKTNAFCVDFENTP...
A5DSM3_LODEL/58-114                  ......m-VEKFKAIADSMEELDLNMRDLQQIHSAISSlFNESFASFLYGLSITMWCVDFASVP...
M1W2F8_CLAP2/52-107                  ......f-EPAFTELSDGLADLEANMMHFQLMHESLSR.FSESFASFLYGLNMNAFCADFPEGP...
Q7S3H5_NEUCR/54-109                  ......f-EPAFAELADAMADLEANMMHFQLMHESLAR.FSEDFASFLYGLNMNAFCVDFPEGP...
U1HUF7_ENDPU/52-107                  .......LEPQFAELADSMADLEANFMHLQLMHESLAR.FGESFAAFLYGLNVRAFCVDFPETP...
I1BI76_RHIO9/32-86                   .......LGPALEQLNKSIRNVSDKYEKLNDLDGTLID.FNRSFGSFLFGLQANNETIHWKH--v..
M7WPB2_RHOT1/61-116                  ......l-SAVFAELADAVSDLTANFEELESVQKRLDG.VNESFAGWLLGLRANGYTVDFLEAP...
E6ZYV2_SPORE/45-100                  .......LQGAMTDLAEEVGVLQLNLENVEAVHESLHS.FNENFAMYIYGLKMNAYCVEWPEAP...
J3NWS8_GAGT3/58-113                  ......f-EPAFAELADAMADLEANMMHFQIMHESLSR.FSESFASFLYGVNMNAFCVEFPEAP...
C5DT85_ZYGRC/66-120                  ......i-LPQIREFSDSMITLDANFTQLNFIHESLVD.LNESLGALLYGLMCNSWCVDFPH--v..
K5W7Y2_PHACS/39-94                   .......LEPALSELLDEAEALQTNVEGLRNLSDALST.FNESFASWLYVMNMNALTTDWPQAP...
A6R6I2_AJECN/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPEAP...
C4R6Y1_PICPG/59-113                  ....ssl----LSELNDSLTTLDANMTKVNSVHESLTN.FNESFSAFLYGLSMNAWCVEYSEAP...
K2S1M9_MACPH/69-124                  .......LEPAFAELSDSMADLEANFMHLQLMHESLAR.FSESFAAFLYGLNMNAFCVDFPEAP...
J4H4C4_FIBRA/40-95                   .......LEPALAELADEVEALNTNVQGLRSLSDALGT.FNESFASWLYVMNMNALTVDWPQAP...
M7T642_EUTLA/68-122                  ......f-EPAFAELSDAVADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEV-...
B8PD84_POSPM/39-93                   .......LEPALSELADEIEALNTSVQCLRSLGDALGT.FNESFASWLYVMNMNALTVDWPQV-...
Q0CSM7_ASPTN/54-108                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEV-...
A0A099P7A6_ISSOR/104-154             aelflet-----------ASKLSLRTKQLKRTNDTVVE.LNESLGAYLFGLYQNAWCVNMN---es.
V5HTZ3_BYSSN/52-107                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
A0A0A2K499_PENEN/51-106              .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
M3K4E2_CANMX/53-109                  ......i-SGKFKNIAESMGTLDQHMDDFQTIHNNISNrFNESFASFLYGLSMTMWCVDFTGYP...
F7W3H4_SORMK/54-109                  ......f-EPAFAELADAMADLEANMMHFQLMHESLAR.FSEDFASFLYGLNMNAFCVDFPEGP...
D8PU57_SCHCM/37-91                   .......MEPAISELSDEMDTLQTHIEGLRHLSETLSI.FNESFASYLYVMEMNGLTTDWPQV-...
G8BA67_CANPC/51-107                  .......IQNKFKDIADGLEDLDVNVRDLNHIHNAVASqFNESFASFLYGLSITMWCVDLPKCP...
I1BI98_RHIO9/32-87                   .......LGPALEQLNKSIRNVSDKYEKLNDLDGALID.FNRSFGSFLFGLQANNETIHWKHSP...
G9N1S4_HYPVG/45-100                  .......LEPAFAELSDAMADLEANMMHFQLIDESLAR.FGESFASFLYGLNMNAFCVDFPESP...
C7ZLR9_NECH7/32-85                   ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFMYGLNMNAFCVDFPE--...
Q2ULJ4_ASPOR/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
A8Q3E8_MALGO/39-93                   ....dda----LPILVEETMTLHDNFAQIAEIQHAMTA.FNESFAAFLYGIKMNAFCVEWPEAP...
G8JN32_ERECY/62-117                  .......LLPQIQELTDSVITLDSNFTHMNFIHESLVD.LNESVSALLYGLMCNSWCVDFPNLP...
G1X6V6_ARTOA/52-107                  .......ITPFFAELEDGLNILHDNLMQLQQIHENINR.FNESFSAMIYGMEMNAFCVDFPEAP...
G0S2K4_CHATD/55-110                  ......f-EPAFAELADAVADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
E9CVH2_COCPS/52-107                  .......LEPQFAELSDSMADLEANFMHLQLLHESLSR.FSESFASFLYGLNMNAFCVDFPEAP...
R8BRL2_TOGMI/57-112                  ......f-EPVFAELSDAMADLEANLMHFQIMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
G4TG26_PIRID/44-99                   .......LEGTFHEIADELEGFMKNLQQIKLITQKLEE.RAESVAMFLQAQRMNTYCVEFPQAP...
R9ADW5_WALI9/37-92                   .......LTPALTDLSDELDGIISSTQQLVELDDALSQ.FNHGFGSLLWSLKLNAYCINWPEAP...
A7F0C8_SCLS1/59-114                  ......f-EPAFAELSDSMADLEANFMHLQLMHESLAR.FSENFASFLYGLNMNAFCVDFPEAP...
C6H6P0_AJECH/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FNENFASFLYGLNMNAFCVDFPEAP...
W7N0W4_GIBM7/52-107                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
B2VXI5_PYRTR/56-111                  .......LQDGFAELSDAMADLEQNFLQLQLMHESLAR.FSESFAGFLYGMNMNAFCVDFPEAP...
R9P4H5_PSEHS/1-52                    .......----MTDLAEEVGVLQLNMTNVEAVHESLHS.FNENFAMYIYGLKMNAYCVEWPEAP...
G4UXD7_NEUT9/54-109                  ......f-EPAFAELADAMADLEANMMHFQLMHESLAR.FSEDFASFLYGLNMNAFCVDFPEGP...
L0PCG7_PNEJ8/39-94                   .......LAPAFAEMADALTDVQHNFEHIQSIHANLVH.FNESFASFLYGLNMNAFCVDFPEAP...
G3J3K5_CORMM/53-108                  ......f-EPALAELSDAMTDLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEAP...
A0A016PWZ0_GIBZA/52-107              ......f-EPAFAELSDAMADLETNMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
M3AK27_PSEFD/66-121                  .......LEPAFGELSDAMADLEANMMHLQLLNESISR.FNENFGAFLYGMNMTAFCVDFPEAP...
R4XFP9_TAPDE/43-98                   .....ld--VAFAELSDAFSDFSANMQQIVELGQDISR.FNESFASFLYGLNVNAFCVDFAEAP...
A0A0D1CUN2_USTMA/45-100              .......LQGAMSDLAEEVGVLQLNLENVEAVHESLHS.FNENFAMYIYGLKMNAYCVEWPEAP...
M7UHC9_BOTF1/59-114                  ......f-EPAFAELSDSMADLEANFMHLQLMHESLAR.FSENFASFLYGLNMNAFCVDFPEAP...
F2PYX3_TRIEC/53-108                  .......LEPQFAELADLMADLEENFVHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPETP...
E3KJ10_PUCGT/62-117                  .......LAPLFVDLSDAITDLHINLSNLDLVCQDLDG.FNEAFSAFIYGLRVNSYVTDFDEAP...
G8YGT2_PICSO/62-118                  .....nl--EKFEYISDGLDELDVNMTNLQQIHEAISDgFNESFASFLYGLSITMWCVDFPGCP...
G9PA35_HYPAI/56-110                  .......LEPAFAELSDAMADLEANMMHFQLIDESLAR.FGESFASFLYGLNMNAFCVDFPEV-...
B0DBU2_LACBS/30-83                   .......LEPAMSEFVDETEALQTNMEGMKNLSDALGT.FNESFASWLYVMNMNALTTDWPQ--...
K0KG33_WICCF/41-95                   ......l--NSFIELNDSLNDFDKNFHKIHDIHQDLTS.FNESFSSFLYGLQVNAYIVEFNEIP...
A0A0A2L9X3_PENIT/51-106              .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
C0NH88_AJECG/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPEAP...
E9EWP8_METRA/61-116                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
H2AS78_KAZAF/56-111                  .......LVPQIRELSDSMITLDDNFIRLNEIHNSLVN.LNESFGSLIYGMMCISACIDFPGIP...
S7ZR90_PENO1/53-108                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGMNMNAFCVDFPEAP...
U5HCP9_USTV1/55-110                  .......LAPVFAELADSLSDLTGNLRELDKSNDHLDG.FNTAFASYLYGLRITAYTADFNEAP...
C1GB70_PARBD/54-109                  .......LEPQFAELADSMADLEANFMYLQLMHESLSR.FNECFASFLYGLNMNAFCVDFPEAP...
S9W4D3_SCHCR/28-88                   .pnlqtf-ANSLAALDDGVNEFRKRMNQLSVTKQNLDS.FNESFASFLYGLQINAFCVDYENAP...
Q0U873_PHANO/103-157                 .......LQDGFAELSDAMADLEQNFMQLQLMHESLAR.FSESFAGFLYGMNMNAFCVDFPEV-...
A0A0D2XIG2_FUSO4/52-107              ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
G3ATN1_SPAPN/43-99                   ......m-LAKFARLADGVEELKSHVTSMEKVHQSVSQeFNEGLASLLYGLSMTMWCVGFSGGP...
S8FC91_FOMPI/39-93                   .......LEPALGELLDDIETLNTNIQGLRNLGDALST.FNESFASWLYVMNMNALTVDWPQV-...
W1Q780_OGAPD/96-148                  ....rqf------EFIDHLDSIHMKLLKLNEIHESLTN.FNESFGSFLFGLNINAWCVNFEEAP...
A0A0B1PE61_UNCNE/59-114              .......LEPAFAELSDSMADLEANFMHLQFMHESLAR.FNENFSSFLYGLHMNAFCVDFPEAP...
M2THS3_COCSN/56-111                  .......LQDGFAELSDAMADLEQNFVQLQLMHESLAR.FSESFAAFLYGMNMNAFCVDFPEAP...
L8G5D6_PSED2/57-112                  ......f-EPAFAELSDSMADLEANFMHLQLMHESLSR.FSESFASFLYGLNMNAFCVDFPEAP...
M4BGH6_HYAAE/5-59                    .....li--GPFTELCGALRGLQEQVEQLKRVHNAVDD.FNSAFGSFQGAMALHASCLSYPK--t..
DAM1_YARLI/33-88                     ......i-GEQMAELADGMSALDRNLKDLQVIHTNLNN.FNESFSTLIYGLQMNAWCAEFHNGP...
E9DVN1_METAQ/59-113                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEV-...
A8NC24_COPC7/1-51                    ......m-----TEFLDEAETLQTNMEGIKQLSESLAT.FNESFASWLYVMNMNALTTDWIQ--i..
K5VSJ3_AGABU/39-94                   .......LEPALAEFVDETEALQSNVEGLVNLSDSLAT.FNESFASWLYVMNMNALTTDWPQTP...
A0A0E1S567_COCIM/52-107              .......LEPQFAELSDSMADLEANFMHLQLLHESLSR.FSESFASFLYGLNMNAFCVDFPEAP...
B8PEV3_POSPM/29-83                   .......LEPALSELADEIEALNTSVQCLRSLGDALGT.FNESFASWLYVMNMNALTVDWPQV-...
A0A099NSU4_ISSOR/34-83               .elflkt-----------ASKLSLRTKQLKRTNDTVVE.LNESLGAYLFGLYQNAWCVNMN---es.
C8V7J7_EMENI/52-107                  .......LEPQFADLADRMAELEANFDKLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
DAM1_DEBHA/54-110                    ......n-TEKFESLSDALEELDVNMTNLQSIHEAISDgFNESFASFLYGLSITMWCVDFPGCP...
N4U0Z8_FUSC1/52-107                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
E7LU88_YEASV/63-118                  .......LLPKIRELSDSIITLDSNFTRLNFIHESLAD.LNESLGSLLYGIMSNSWCVEFSQAP...
A0A060SKK8_PYCCI/37-78               .......IEPALAELIDEAEALQTNVEGLRNLSDALGT.FNESFASWL----------------hr.
B2AKR3_PODAN/63-118                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
G3BCW7_CANTC/48-104                  .......ITDSFERLHDSVQDLEMYMKHLQRLHEAISQgFNESFSSFLYGLSITMWCIDFPSTP...
M9MC12_PSEA3/45-100                  .......LQGAMSDLAEEVGVLKLNLESIEAVHDSLHS.FNENFAMYMYGLKMNAYCVEWPEAP...
C5MBE3_CANTT/55-111                  ......i-VEKFNDIAQSMEILDNNMNDLCHIHDNLSNqFNESFASFLYGLSMTMWCVDFPGCP...
K9FW94_PEND2/51-106                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
DAM1_CANGA/54-109                    .......LLPQIKDLTDSVVTLDSNMTRLNFIHDNLVD.LNESFGSLLYGLMCNSWCVEFPNAP...
A0A067CQR5_SAPPC/5-58                ......i-EREMRRIRNAMRALDANVKKLAAVNNHIVT.FNSRFGGLMTGISLQQSCIE-----ppk
M3AU07_SPHMS/1-45                    .......-----------MADLEANMMHLQLLNDSLSR.FSENFGAFLYGMNMTAFCVDFPEAP...
E5QZ96_ARTGP/53-108                  .......LEPQFAELADAMADLEENFVHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPETP...
R1EKR8_BOTPV/69-124                  .......LEPQFAELSDSMADLEANFMHLQLMHESLAR.FSESFAAFLYGLNMNAFCVDFPEAP...
S3BTL9_OPHP1/54-109                  ......f-EPAFAELSDAMTDLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAYCVDFPEGP...
U9T2I6_RHIID/44-99                   ....fer---PLVELEKSFNNLSEHFKNIKKVQASLDE.FNKSFSGFLYGIKMNAHCVEFSEAP...
A7TEY5_VANPO/70-125                  .......LIPNIRQISDSLATLDKNFSDLNIIQENLVD.FNESLGSLLYGLMCNSWCVAFPHVP...
E7KNS6_YEASL/63-118                  .......LLPKIRELSDSIITLDSNFTRLNFIHESLAD.LNESLGSLLYGIMSNSWCVEFSQAP...
K1X003_MARBU/50-105                  ......f-EPSFAELSDSMADLELNFMNLQVLNDSLSR.FSENFASFLYGLNMNAFTTDFPEAP...
E3RNH1_PYRTT/56-111                  .......LQDGFAELSDAMADLEQNFLQLQLMHESLAR.FSESFAAFLYGMNMNAFCVDFPEAP...
B6HPL0_PENCW/51-105                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEV-...
C5FL19_ARTOC/48-103                  .......LEPQFAELADSMADLEENFAHLQLMHESLSR.FNESFASFLYGLNMNAFCVDFPETP...
DAM1_ASHGO/62-117                    .......LLPQVQELKDSMITLDANLTHMNFIHESLVD.LNESVSALLYGLMCNSWCVDFPNMP...
L8WZ01_THACA/36-91                   .......LEPAFAEFADEAAAMHRNIERMGDLYETLET.FNESFSSFLYALNMNAYTVEWPQAP...
S8CA78_DACHA/52-107                  .......ITPFFAELEDGLNILHDNLLQLQQIHENINK.FNENFSAMMYGMEMNAFCVDFPEAP...
M7PDN8_PNEMU/39-94                   .......LAPAFAEMADALIDVQQNFEHVQSIHSNLVQ.FSESFASFLYGLNMNAFCVDFPEAP...
G4NDS4_MAGO7/57-112                  ......f-EPAFAELSDAMADLEANMMHFQIMHESLSR.FTESFASFLYGVNMNAFCVEFPEAP...
N1J916_BLUG1/58-113                  .......LEPSLSELSDSIADLEANFMHLQIMHESLSR.FSENFASFLYGLNMNAFCVDFPEAP...
G7E6Q5_MIXOS/40-95                   .......LESVFGELRDAMEDYSSHMASLCEINNGLDR.FNQAFAGYLYGLKMNAYTTEYSEAP...
F0XEH0_GROCL/54-109                  ......f-EPAFAELSDAMADLEANMMHYQLMHESLSR.FSESFASFLYGLNMNAYCVDFPEGP...
G2QJY2_THIHA/51-106                  ......f-EPAFAELSDSIADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
DAM1_KLULA/50-104                    ......v-LPQLQELSDSMVTLDGNMTHMNFIHESIAD.LNEALSALLYGLMCNSWCVDFPNI-...
H6C1X1_EXODN/54-109                  .......LEPQFAELGDSMADLEANMMHLQLMHESLSR.FAESFASFLYGLNMNAFVVDFPEAP...
M5FZ72_DACSP/40-95                   .......LAPVLSDLTDEADALQHNLEQLNGLYDALGT.FNEAFASYLYALRMNAFCVEWQQAP...
E5A323_LEPMJ/56-110                  .......LQDGFAELSDAMADLEQNFMQLQLMHESLAR.FSESFAGFLYGMNMNAFCVDFPEA-...
K3VWI8_FUSPC/52-107                  ......f-EPAFAELSDAMADLETNMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
L2FFX5_COLGN/52-106                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDYPE--n..
T0KFL8_COLGC/110-165                 ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDYPEGP...
N4VN04_COLOR/49-104                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFQEGP...
R7YYN5_CONA1/59-114                  .......LEPAFAELSDGMADLEANFMHLQLMHESLAR.FSESFAAFLYGLGMNAFCVDFPEAP...
B8N236_ASPFN/54-109                  .......LEPQFAELADSMADLEANFMHLQLMHESLTR.FSESFASFLYGLNMNAFCVDFPEAP...
N1RMT8_FUSC4/52-107                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLAR.FSESFASFLYGLNMNAFCVDFPEGP...
C9SRA7_VERA1/54-109                  ......f-EPAFAELSDAMADLEANMMHFQLMHESLSR.FSESFASFLYGLNMNAFCVDFPEGP...
#=GC seq_cons                        ........pPtFuELuDuhs-L-uNhh+LphhHESLuc.FsESFASFLYGLsMNAaCVDFPEuP...
//
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