GenomeNet

Database: Pfam
Entry: DDR
LinkDB: DDR
Original site: DDR 
#=GF ID   DDR
#=GF AC   PF08841.8
#=GF DE   Diol dehydratase reactivase ATPase-like domain
#=GF AU   Mistry J
#=GF SE   pdb_2d0o
#=GF GA   24.60 24.60;
#=GF TC   24.60 24.70;
#=GF NC   24.50 24.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9990728
#=GF RT   Biochemistry of coenzyme B12-dependent glycerol and diol
#=GF RT   dehydratases and organization of the encoding genes. 
#=GF RA   Daniel R, Bobik TA, Gottschalk G; 
#=GF RL   FEMS Microbiol Rev. 1998;22:553-566.
#=GF RN   [2]
#=GF RM   16338403
#=GF RT   Release of a damaged cofactor from a coenzyme B12-dependent
#=GF RT   enzyme: X-ray structures of diol dehydratase-reactivating
#=GF RT   factor. 
#=GF RA   Shibata N, Mori K, Hieda N, Higuchi Y, Yamanishi M, Toraya T; 
#=GF RL   Structure. 2005;13:1745-1754.
#=GF DR   INTERPRO; IPR030994;
#=GF CC   Diol dehydratase (DDH, EC:4.2.1.28) and its isofunctional
#=GF CC   homologue glycerol dehydratase (GDH, EC.4.2.1.30) are enzymes
#=GF CC   which catalyse the conversion of glycerol 1,2-propanediol, and
#=GF CC   1,2-ethanediol to aldehydes [1].  These reactions require
#=GF CC   coenzyme B12.  Cleavage of the Co-C bond of coenzyme B12 by
#=GF CC   substrates or coenzyme analogues results in inactivation during
#=GF CC   which coenzyme B12 remains tightly bound to the apoenzyme.  This
#=GF CC   family comprises of the large subunit of the diol dehydratase
#=GF CC   and glycerol dehydratase reactivating factors whose function is
#=GF CC   to reactivate the holoenzyme by exchange of a damaged cofactor
#=GF CC   for intact coenzyme.
#=GF SQ   81
#=GS G7V6B4_THELD/278-606      AC G7V6B4.1
#=GS A0A0K8JAP0_9FIRM/275-602  AC A0A0K8JAP0.1
#=GS V5XIJ9_MYCNE/256-514      AC V5XIJ9.1
#=GS K6DUM9_BACAZ/274-601      AC K6DUM9.1
#=GS A0A0G3Q651_KLUIN/275-602  AC A0A0G3Q651.1
#=GS C0E8B5_9FIRM/284-613      AC C0E8B5.1
#=GS E3GH67_EUBLK/273-600      AC E3GH67.1
#=GS I4EQU8_MODMB/277-610      AC I4EQU8.1
#=GS A0A075KEJ4_9FIRM/275-602  AC A0A075KEJ4.1
#=GS R5TMH6_9FIRM/272-599      AC R5TMH6.1
#=GS D2S4X8_GEOOG/285-618      AC D2S4X8.1
#=GS J3ES93_9LACO/277-604      AC J3ES93.1
#=GS I6XQD8_PROPF/275-602      AC I6XQD8.1
#=GS I2BBY5_SHIBC/277-604      AC I2BBY5.1
#=GS A6TE97_KLEP7/277-604      AC A6TE97.1
#=GS A0A0A1G215_9MYCO/267-570  AC A0A0A1G215.2
#=GS A0A090ULN5_9ENTR/275-602  AC A0A090ULN5.1
#=GS D7GD20_PROFC/273-600      AC D7GD20.1
#=GS I6H1Y8_SHIFL/275-602      AC I6H1Y8.1
#=GS A0A0F5HML0_9BACI/274-601  AC A0A0F5HML0.1
#=GS B2TLK5_CLOBB/278-605      AC B2TLK5.1
#=GS A1TGM6_MYCVP/268-571      AC A1TGM6.1
#=GS S0RQE9_ENTAV/276-603      AC S0RQE9.1
#=GS F7NH21_9FIRM/274-601      AC F7NH21.1
#=GS Q8Y7W3_LISMO/275-602      AC Q8Y7W3.1
#=GS D8JB91_HALJB/277-605      AC D8JB91.1
#=GS A0A089PLR2_PLUGE/277-604  AC A0A089PLR2.1
#=GS A0A0F4LUE7_9LACO/278-605  AC A0A0F4LUE7.1
#=GS I9LEU7_9FIRM/275-602      AC I9LEU7.1
#=GS C6JP61_FUSVA/274-601      AC C6JP61.1
#=GS A0A0M2U968_9FIRM/274-601  AC A0A0M2U968.1
#=GS A0A0F2Q594_9CLOT/275-603  AC A0A0F2Q594.1
#=GS D1AFL7_SEBTE/275-602      AC D1AFL7.1
#=GS A6TDD5_KLEP7/275-602      AC A6TDD5.1
#=GS A5VMA9_LACRD/278-605      AC A5VMA9.1
#=GS I4BU32_ANAMD/277-605      AC I4BU32.1
#=GS A0R5U9_MYCS2/262-565      AC A0R5U9.1
#=GS R5BN42_9FIRM/275-602      AC R5BN42.1
#=GS D2Z8G8_9BACT/278-606      AC D2Z8G8.1
#=GS E3CVA2_9BACT/277-605      AC E3CVA2.1
#=GS A9MLQ0_SALAR/275-602      AC A9MLQ0.1
#=GS Q8XLV8_CLOPE/280-607      AC Q8XLV8.1
#=GS G9YVN8_9FIRM/274-601      AC G9YVN8.1
#=GS V5X9M2_MYCNE/272-605      AC V5X9M2.1
#=GS R6G9W5_9FIRM/273-601      AC R6G9W5.1
#=GS A0A0H3J8Q7_CLOPA/275-602  AC A0A0H3J8Q7.1
#=GS E4RMA0_HALHG/276-603      AC E4RMA0.1
#=GS I6GPC4_SHIFL/273-600      AC I6GPC4.1
#=GS R5RU48_9FIRM/273-600      AC R5RU48.1
#=GS E3H9G3_ILYPC/274-601      AC E3H9G3.1
#=GS A0A0F3RTY4_9LACO/276-603  AC A0A0F3RTY4.1
#=GS I3VRW4_THESW/275-603      AC I3VRW4.1
#=GS J2IRT7_9ENTR/273-600      AC J2IRT7.1
#=GS F0Z327_9CLOT/273-600      AC F0Z327.1
#=GS Q03Q33_LACBA/276-603      AC Q03Q33.1
#=GS G8PEJ6_PEDCP/276-603      AC G8PEJ6.1
#=GS F9ELP3_FUSNU/274-601      AC F9ELP3.1
#=GS B8FDN6_DESAA/272-599      AC B8FDN6.1
#=GS R5XK30_9FIRM/273-600      AC R5XK30.1
#=GS A0A0D1VHX9_ANEMI/276-603  AC A0A0D1VHX9.1
#=GS C4LFD2_TOLAT/275-602      AC C4LFD2.1
#=GS A0A0M3DJ14_9CLOT/278-605  AC A0A0M3DJ14.1
#=GS S2WWZ2_9ACTN/274-601      AC S2WWZ2.1
#=GS O31043_SALTY/275-602      AC O31043.2
#=GS A8AEN2_CITK8/275-602      AC A8AEN2.1
#=GS G2G2A6_9FIRM/275-602      AC G2G2A6.1
#=GS A0A090U426_9ENTR/273-600  AC A0A090U426.1
#=GS A0A0E3MC80_CLOSL/272-599  AC A0A0E3MC80.1
#=GS H6LEQ0_ACEWD/273-600      AC H6LEQ0.1
#=GS E6MIY1_9FIRM/273-600      AC E6MIY1.1
#=GS A1UN21_MYCSK/264-567      AC A1UN21.1
#=GS R6EEW3_9FIRM/1-159        AC R6EEW3.1
#=GS A0A0M2K4E0_9MYCO/260-563  AC A0A0M2K4E0.1
#=GS D2TPR1_CITRI/275-602      AC D2TPR1.1
#=GS H1LI38_9LACO/276-603      AC H1LI38.1
#=GS E3HDB0_ILYPC/274-601      AC E3HDB0.1
#=GS F9DQU4_9BACL/277-604      AC F9DQU4.1
#=GS R6G8Y1_9FIRM/273-601      AC R6G8Y1.1
#=GS A0A0A7FXY5_9CLOT/279-606  AC A0A0A7FXY5.1
#=GS D5XBU6_THEPJ/275-603      AC D5XBU6.1
#=GS D9S1P8_THEOJ/273-600      AC D9S1P8.1
G7V6B4_THELD/278-606                 .....................................................................................................................................VNVESGAEAIMKVLEESQPVKNIFGQPGTNVGGMMERVRRTMSNLTGL......PVADIHIKDLLAVDTLVPQR.........VVGGIAGEFSQEHGVALAVMVETEKLP...MTQLAEAISQET......GVK.VMIGG..V..EAE.M.AVRGALTTPGT.K.K.PLAILDLGAGSTDASLMKENGEI..DL..I.HL.A.G..A..G....N....M....VN....TIIA..S......E..L....G......IE.S.....MELAESIK.R.YPLCKVESPFHVRQEDGRVRFFD.NPLSPNLFGKNALV.VEdDILMPL..ELDIPVERIREIRRRAKREVFVTNSLRALERV..SPAGNVRLL.DYVVLVGGSALDFEIPSMITDALSRFGVVAGRGNIRGTEGPRNAVATGLVL--gf................................................................................................
A0A0K8JAP0_9FIRM/275-602             .....................................................................................................................................VDVEAGATKIMEAVERVQPVVDVQGEAGTNVNGMLERVRQVMGELTGQ......PLSEMKIQDILAVDTFVPQK.........VQGGLAGEFALETAVALAAMVKTSRLP...MQQIADVLTERL......HVR.VVIAG..V..EAN.M.AILGALTTPGT.A.K.PLAILDMGGGSTDAATVTGDNQV..FS..I.HL.A.G..A..G....D....M....VT....MLIN..S......E..L....G......LN.D.....FDLAEEIK.K.YPLAKVESLYHIRLEDGTVKFFE.QHLDPEVFARVVIL.RG.QDMIPI..PTKHSLDKIRHVRREAKKRVFVTNALRSLVRV..APTGNIRHM.EFVVLVGGSALDFEVADMVSDALAEYGIVCGRGNIRGTEGPRNAVATGLVLS-h.................................................................................................
V5XIJ9_MYCNE/256-514                 ...................................................................................................................dglvhivqladiaaaanv------------------------------------------------......--------------------.........----------RRGAVAVDSLVMATMGGddvSPADADALAAAL......GVP.VTRID..S..EAA.A.ARAGALTTPGL.P.A.DVVVVDVGGGTVD--VVAAGDRV..VL..-.--.P.G..A..G....Q....L....LT....AATA..A......A..L....D......I-.S.....TSAAEYAK.R.AEAVTAVTVQLVEDEHGRRRFLD.TPIDGRSTGWLLTA.AP.SGLLPF..TAAMAAAEWRSWRLAAKRLVIGGNVTRGVQDV..GADA-----.TAVLLVGGGAGDDELVRALAERLGH-DVSVGRGNVAGELGHRFAVAYGLVV--la................................................................................................
K6DUM9_BACAZ/274-601                 .....................................................................................................................................VDVDEGAEKMMHAMTNAAPIEDIKGEAGTNAGGMLERVRQVMSELTKQ......QPDDIKIQDLLAVNTFIPQK.........VKGGLAEEFSMENAVGIAAMVKADKLQ...MQMIADELRSRI......NVK.VEVGG..V..EAD.M.AIRGALSTPGT.N.V.PIAIVDMGAGSTDASIITKSGKT..TS..V.HL.A.G..A..G....D....M....VT....MLIN..S......E..L....G......LD.D.....IALAEDIK.K.YPLAKVESLFHIRHEDGTVQFFE.RPLEPHVFARVVIL.KE.GTMIPI..PGQHSVEKVKIVRRGSKEKVFVTNALRALTMV..APTGNIREM.EFVVLVGGSALDFEIPQLVTDALSQYSIVAGRGNIRGTEGPRNAVATGLILA-l.................................................................................................
A0A0G3Q651_KLUIN/275-602             .....................................................................................................................................VDVAAGADAIMKAVNECPTLDNVTGEAGTNIGGMLEHVRQTMAELTNK......PSSDVFIQDLLAVDTAVPVN.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIAHEIEQKL......HVD.VQVGG..A..EAE.A.AIFGALTTPGT.S.R.PLAILDLGAGSTDASIITPQGQI..TA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPAVFARVCVV.KP.DELVPL..PGDLALEKVRIIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYRLVAGRGNIRGVEGPRNAVATGLILSW..................................................................................................
C0E8B5_9FIRM/284-613                 .....................................................................................................................................IEVNSGADHIMKELASCHEILDIAGEQGTNVGALINRIKQSMSELTGE......SVDEMKIIDMLAADTFASVE.........VAGGLAGEAAMENVVMLAAMVQTSKLP...MQAIADELSKLT......GIY.VRVEG..R..EAE.M.ALKGALTTPGA.D.I.PLAILDLGGGSTDAALIDGDGRV..TA..I.HH.A.G..A..G....E....M....VT....KIID..L......E..L....D......LN.D.....RDTAELIK.K.YPLAKVEGLLYLRFEDGSVKFAS.EPLPPQLFSRVVIV.TE.DQLVPIrsSKRLTIDRIALVRREAKKKVFNVNAKRALTEV..APGGDIRKI.GSVALVGGSSQDFEIADLLAEYLSSYRITAGRANLLGMLEPHSAVALGLAL--ad................................................................................................
E3GH67_EUBLK/273-600                 .....................................................................................................................................VNVDEGAEIIMDAIRSVAPVEDVKGEAGTNAGGMLEKVRQVMSNLTEQ......NPQNIKIQDLLAVDTFVPQS.........VKGGMADEFSMENAVGIAAMVKADKLQ...MNMIAEVLEKEL......NVK.VEVGG..V..EAD.M.AIRGALTTPGS.N.K.PLAIIDMGAGSTDAAIINRAGEI..HS..I.HL.A.G..A..G....N....M....VT....MLIG..S......E..L....G......FE.D.....SGLAEDIK.K.YPLAKVESLFHIRHEDGTVQFFD.EPLDPRSFARVVIL.TP.SGMVPI..PGNHSLERIRTVRREAKTKVFVVNAIRSLERV..SPTGNVRDI.EFVTLVGGSALDFEIPQLVTDALSKFSIVAGRANIRSVEGPRNAVATGLVLAY..................................................................................................
I4EQU8_MODMB/277-610                 .....................................................................................................................................VDVDAGAEAIMDAVGRAQPLDDARGEPGTHVGGMLAQVRDTMADVMDSpglpavPVAEIAIRDVLAVDTFVPAE.........VRGGLAGEVALENAVALAAMVSTSRSR...MQVVADQVSEGL......GAA.AAIGG..V..EGE.M.AVSGALTTPGV.D.R.PVAVLDLGGGSTDAALLTRDGRA..TA..V.HV.A.G..A..G....E....L....VT....KLVH..S......E..L....A......LG.D.....REVAESVK.R.CPLAQVESFFHVRHEDGTVQFFE.TPLPPEVYARVVVL.TP.EGPAPV..GTRHRLDHVRRVRREAKRRVFVVNALRALRQV..APGGNLREL.DFVVLLGGSALDFEIPDMIADALAPHGVVCGTGNVLGTEGPRNAVATGLVRA-w.................................................................................................
A0A075KEJ4_9FIRM/275-602             .....................................................................................................................................IDVESGANKIMETVERVQPVLDVQGEAGTHVNGMLERVRQVMSELTEQ......PLADMKIQDILAVDTFVPQK.........VQGGLAGEFALENAVALAAMVKTSRLP...MQQIANKLTQEL......GVK.VVIAG..V..EAN.M.AIRGALTTPGT.D.K.PLAILDMGGGSTDAAIITRDERV..MS..I.HL.A.G..A..G....D....M....VT....MLIN..S......E..L....G......LN.D.....FDLSEDIK.K.YPLAKVESLYHIRLEDGTVRFYE.QHLKPEVFSRVVIL.KD.GDMVPI..PSSHPLDKIRHVRREAKKRVFVTNALRSLARV..APTGNIRHI.EFVVLVGGSAMDFEVGDMVTDALAEYSIVCGRGNIRGSEGPRNAVATGLVLSY..................................................................................................
R5TMH6_9FIRM/272-599                 .....................................................................................................................................VDLDEGAEKIMQVVSDAGTIYDMEGEHDTNVGNMFSRIKQGMENLDET......AKREIHITDILAVDTMAPVR.........ISGALAGETCLEKAVGIAAMVKTRHLP...MQKIAEQLRIEL......GVN.VMVAG..V..EAV.M.ASLGALTTPGT.S.L.PLAILDMGGGSTDAAVISEDGKV..SM..T.HQ.A.G..A..G....E....L....VS....MLIE..T......E..L....G......LG.D.....RHMAEQIK.K.YPLAKVESLFHMRMENGQMTFVE.QSIDPRFYGRVVLL.TE.DGMIRL..EQDIPMEKIVQVRREAKRKVFVTNAFRALKKV..APGQDLKHI.SNVVLVGGSAEDFEIPEMLMEELSEFRIVCGRGNIRGEEGPRNAVATGLVLSY..................................................................................................
D2S4X8_GEOOG/285-618                 .....................................................................................................................................VDVDAGAEAIMEVVGRAQPLDDARGEPGTHVGGMLAQVRDTMADVMDVagqpdvPVSDIAIRDVLAVDTFVPAE.........VRGGLAGEVALENAVALAAMVRTSRSR...MQLVADLVSEGL......GAA.AEIGG..V..EGE.M.AVGGALTTPGV.D.R.PIAVLDLGGGSTDAALLTREGEC..TA..V.HV.A.G..A..G....E....L....VT....KLID..S......E..L....A......LG.D.....REVAEGVK.W.FPLGKVESFFHLRHEDGTVEFVD.QPLPPHVFARVVVL.TP.DGPAPV..PTRHGLDHVRRVRREAKRRVFVVNALRALRQV..APGGNLRAL.EFVVLLGGSALDFEIPDMIADALAPHGIVCGTGNVLGTEGPRNAVASGLVR--ah................................................................................................
J3ES93_9LACO/277-604                 .....................................................................................................................................VGISDGADKIMKVISSFKTIDDVTGEPGTNIGGMLERVRQTMAELTGK......QLNEIAIQDLLGVNTSVPIN.........VKGGLAGEFSMEQAVGIASMVKSDRLQ...MSRIAKEIEKEL......NVK.VDIGG..A..EAE.A.AILGALTTPGT.T.K.PIAILDLGAGSTDASIINKENKI..VA..I.HL.A.G..A..G....D....M....VS....MIIN..S......E..L....G......LD.D.....PYLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KALPADIFAKTVVV.KP.TGYEPI..PGELSIEKIRIVRRTAKKRVFVANAIRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYNLVAGRGNVRSVEGPRNAVATGLILRY..................................................................................................
I6XQD8_PROPF/275-602                 .....................................................................................................................................VDVDLGAAEIMDVASRIRNLSDITGEAGTNVGGMMEKVRVTMAQLTNQ......HTRDIRITDLLAVDTRVPQQ.........VAGGIANEFSMEAAVGIAVMVRTDRLQ...MERIASELAAEI......GVP.VEVGG..V..EAD.M.AIRGALTTPGT.A.A.PIAILDMGAGSTDASVMRPDGTG..TS..I.HL.A.G..A..G....N....M....VT....LMIQ..S......E..L....G......LD.S.....FDLAEDIK.R.HPLAKVESVFNIRHEDGTVQFFE.DPLPGHVYARTVVL.KP.DGMVPL..DVDLPVETIRQVRIRAKEQVFVTNAIRALQRV..SPTSEVRGI.DFVVLVGGSALDFEIPQLVTRALADYRVVAGRANIRGVEGPRNAVATGLVL--gg................................................................................................
I2BBY5_SHIBC/277-604                 ....................................................................................................................................a-DVACGAGAIMQAVAECAPVSDIRGEPGTHAGGMLERVRQVMASLSGH......GAHEVFIQDLLAVDTFIPRK.........VQGGLAGEFSMENAVGIAAMVKSDRLQ...MEVIAGELSQRL......ATR.VEVGG..V..EAN.M.AISGALTTPGS.D.T.PLAILDLGAGSTDAATINRAGQV..KS..V.HL.A.G..A..G....N....M....VS....LLIK..T......E..L....G......LS.E.....LQLAEEIK.K.YPLAKVESLFSIRHENGAVEFFR.EPLSPAVFAKVVYI.KE.GTLVPI..DNQTSLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGEIRDI.AFVVLVGGSALDFEIPQLITDALSHYGVVAGQGNIRGTEGPRNAVATGLVL--gm................................................................................................
A6TE97_KLEP7/277-604                 ....................................................................................................................................a-DVAEGAEAIMQAMSACAPVRDIRGEPGTHAGGMLERVRKVMASLTGH......EMSAIYIQDLLAVDTFIPRK.........VQGGMAGECAMENAVGMAAMVKADRLQ...MQVIARELSARL......QTE.VVVGG..V..EAN.M.AIAGALTTPGC.A.A.PLAILDLGAGSTDAAIVNAEGQI..TA..V.HL.A.G..A..G....N....M....VS....LLIK..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYGVVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
A0A0A1G215_9MYCO/267-570             .....................................................................................................................................VEFRIDGVPVRYSPAQAHAI--LRREPPGSVVRI--RLRSIPTADGEI......AVDDAFFTDLAALDSGTWLRrgvaeargtVVALLAADHVEDAATTLAELT------...------------......GRP.ARTIA..T..EPE.A.AARGARTTPGL.P.P.ESVVCDIGGGTID--LIGSERTV..TA..-.--.A.G..A..G....E....S....IT....VAVA..R......M..L....N......I-.P.....RALAERVK.R.TPAIRVEGPHVAHEEDGRRLFLD.APAPADAIGRLCTR.GT.AGLVPF..STKLAAEEWRSLRLAIKQETVAANIARCLAAF..EKPP-----.PALVLAGGGALDDELLRTVGESLRSVGVVVGRANIDGVHGPRFAVASGLVH--ls................................................................................................
A0A090ULN5_9ENTR/275-602             .....................................................................................................................................VDVAAGADAIMKAVGECPKLDNVTGEAGTNIGGMLEHVRQTMAELTNK......PSQEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIAQEITQKL......NID.VQVGG..A..EAE.A.AILGALTTPGT.T.R.PLAILDLGAGSTDASIINPKGEI..IA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LD.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.EPLPPTVFARVCVV.KP.DELVPL..PGELALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYRLVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
D7GD20_PROFC/273-600                 .....................................................................................................................................VDVDRGAQEIMHAAESVGTIRDIKGEPGTNIGGMMEKVRVTMGRLTDR......DPAGIEVTDLLAVDTNVPQK.........VTGGVAGEFSPEAAVGIAVMVKADRLQ...MQRIAEEMTEQF......AVR.VEVGG..V..EAD.M.AIRGALTTPGT.S.V.PIAILDMGAGSTDASVLREGQPA..RS..V.HL.A.G..A..G....N....M....VT....LLIK..M......E..L....G......LD.S.....EEDAENIK.R.YPLARVETLFSIRHEDGTVQFFD.EPLAPELFARTVVL.HP.DGMIPL..PLRHPLEVIRQVRIHAKQRVFVTNAMRALAAV..SPTNNVRDI.AHVVLVGGSALDFEIPQFVTHALAEFRVVAGRANTRGTEGPRNAVATGLVLA-w.................................................................................................
I6H1Y8_SHIFL/275-602                 .....................................................................................................................................VDVAAGADAIMKAVGECPKLDNVTGEAGTNIGGMLENVRQTMAELTNK......PSHEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIAQEITQKL......NVD.VQVGG..A..EAE.A.AILGALTTPGT.T.R.PLAILDLGAGSTDASIINPKGDI..IA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LD.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPTVFARVCVV.KP.DELVPL..PGDLALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYRLVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
A0A0F5HML0_9BACI/274-601             .....................................................................................................................................VDVDEGAEKMMSVLTASAPIEDIKGEPGTNAGGMLERVRQVMSELTSQ......PPDAIKIQDLLAVNTFNPQM.........VKGGLAEEFSMENAVGIAAMVKADKLQ...MQMIADELQSRV......DIE.VEVGG..V..EAD.M.AVRGALSTPGT.N.L.PVAIVDMGAGSTDASTMTREGNI..TS..V.HL.A.G..A..G....D....M....VT....MLIN..S......E..L....G......LD.D.....IDLAEDIK.K.YPLAKVESLFHIRHEDGAVQFFE.EPLEPHVFARVVIL.KD.GYMIPI..PGQHSIEKIRTIRRGAKEKVFVTNAIRALSMI..SPTGNIREM.EFVVLVGGSALDFEVPQLVTDALSQYGVVAGRGNIRGTEGPRNAVATGLVLA-l.................................................................................................
B2TLK5_CLOBB/278-605                 .....................................................................................................................................VDVEHGAEKIMDAVNLCVPIQDVKGEAGTNAGGMLERVRQVMANLTKQ......KISDITIQDLLAVDTFIPQM.........VKGGLAAEFSMENAVGIAAMVKADKLQ...MQMIADKLQEQL......NVP.VEVGG..V..EAD.M.AIRGALTTPGS.S.T.PLAILDMGAGSTDASIINKQGEI..CS..I.HL.A.G..A..G....N....M....VT....MLIK..S......E..L....G......LE.D.....FSLAEDIK.K.HPLAKVESLFHIRHEDGTVEFFQ.KPLDSSVFAKVVIL.KD.GMLVPI..DGQNSLEKIRNIRKCAKEKVFVTNCLRALKIV..SPTGNIRDI.EFVVLVGGSSLDFEVPQVVTNALSQYGVVAGRGNIRGSEGPRNAVATGLVLA-f.................................................................................................
A1TGM6_MYCVP/268-571                 .....................................................................................................................................VDVRVDGALVRYTPAEAHGV--LRRSVPGCVNAI--RLRSVPTAASGL......SVHDAFFTDLGSIDNGAWLRrgvadaqgtVVALLAAEEADDAAASLSELT------...------------......GRP.ARTLS..S..EPE.A.AAWGARTTPGL.P.P.GSMVCDIGGGTVD--LIGADGTV..VA..-.--.A.G..A..G....E....S....IT....VAVA..R......V..L....G......I-.P.....HALAETVK.R.TPAVRVEGPHVAHEEDGRRVFLD.SPASSDAIGRLCTR.GS.AGLVPF..SDRLAAEEWRSLRLAIKQETVAANIARCLTAFgeSPTA-----.--LVLAGGGALDDELMRTVGEALRSVPIVVGRADVDGVHGPRFAVARGLIAMY..................................................................................................
S0RQE9_ENTAV/276-603                 .....................................................................................................................................VGISAGAEKIMETVSAFEVIDNVTGEPGTNVGGMLEKVRLTMAELTDR......PVNQIFIQDLLAVDTFVPIS.........VKGGLAGEFSMEQAVGIASMVKSDHLQ...MSKIADAIQQDL......GIK.VEIGG..A..EAE.A.AILGALTTPGT.S.A.PLAILDLGAGSTDASIIKKDERI..VA..T.HL.A.G..A..G....D....M....VT....MLIQ..S......E..L....G......LE.D.....VYLAEDIK.K.YPLAKVENIFYIRHEDGSVQFFD.QPLDPSLFAKVVVV.TP.DGYVPI..PGDDSIEKIRLVRQTAKERVFVTNALRALRRV..SPTGSIRDI.PFVVIVGGSALDFEVPQIVTNALSHYGLVAGRGNIRQIEGPRNAVATGLILSY..................................................................................................
F7NH21_9FIRM/274-601                 .....................................................................................................................................IDVEAGAAKIMAAVEQVQPVQDVQGEAGTNVNGMLERVRQVMSELTGQ......PLDAMKIQDILAVDTFVPQK.........VQGGLAGEFALENAVALAAMVKTSRLP...MQQIADQLRRQL......GVR.VVIAG..V..EAN.M.AIRGALTTPGT.D.K.PLAILDMGGGSTDAAIISRDERT..SA..I.HL.A.G..A..G....D....M....VT....MLIH..S......E..L....G......LN.D.....LALAEEIK.M.YPLAKVESLYHIRLEDGTVQFFE.QHLPPQVFSRVVIL.KE.SEMIPI..PTDHPLDKIRHVRREAKRRVFVTNALRALTRV..APTGNIRHI.SFVVLVGGSALDFEVADMVTDALAEYGIVCGRGNIRGTEGPRNAVATGLVLSY..................................................................................................
Q8Y7W3_LISMO/275-602                 .....................................................................................................................................VNVAEGSEKIMQAIMSLPKLDNASGEPGTNIGGMLEKVRQTMAGLTDK......LPADIFIQDLLAVDTFVPVD.........VQGGLAGEFSMEQAVGIASMVKSDHLQ...MAAIASEIEQEL......QVS.VKIGG..A..EAE.A.AILGALTTPGT.N.T.PLAILDLGAGSTDASIINGKGEI..IA..T.HL.A.G..A..G....D....M....VT....MIIQ..S......E..I....G......LE.D.....RYLAEDIK.K.YPLAKVESIFHIRHEDGTVQFFD.TPLSPTVFAKVVIV.KP.DGFVPI..PGDVSIEKIKLIRRSAKERVFVTNTIRALKYV..SPTGNIRDI.PFVVIVGGSALDFEIPQLITDALSHYSLVAGRGNIRGKEGPRNAVATGLILA-g.................................................................................................
D8JB91_HALJB/277-605                 .....................................................................................................................................IGIDQGADEIMAQVEDLWPIDDIRGERGSNIGGMLSRAREQMGEITGQ......EFSEINIRDIMAVDTLVPQA.........VEGSVASEHSMETAVGLAAMVKTSELP...MQQIADEVEDRL......ETT.VHIQG..I..EAN.M.AILGSLTTPGT.D.V.PFAILDMGGGSTDAAYIDADNDI..TS..I.HL.A.G..A..G....D....M....VT....MLIA..S......E..L....G......LD.D.....WELAEGLK.K.YPVAKVETLFSIRHEDGTVTFLD.EAVDSETFGRIVLL.TDdGDMEPV..SIDESVEKVRRTRRRAKERVFVANAKRALRQI..SPTKSVRYH.SFVVMVGRSALDFEIPELISDALAEYGIVCGRGNIRSTTGPRNAVATGLCLSY..................................................................................................
A0A089PLR2_PLUGE/277-604             ....................................................................................................................................a-DVARGADGIMQAMAGCAPVQDIRGEAGTHAGGMLERVRSVMATLSGH......AMSDIRIQDLLAVDTFIPRK.........VQGGIAGEFSMENAVGIAAMVKSDRLQ...MQAIASALSERL......HTE.VVVGG..V..EAN.M.AVAGALTTPGC.A.A.PLAILDLGAGSTDAAIISAEGSV..KS..V.HL.A.G..A..G....N....M....VS....LLIK..T......E..L....G......LS.E.....LHLAEELK.K.YPLAKVESLFSIRHENGAVEFFR.EPLSPSVFAKVVYI.KD.GELIPV..DNLTSLEKIRTVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEVPQLITDALSHYGVVAGQGNIRGTEGPRNAVATGLVLA-c.................................................................................................
A0A0F4LUE7_9LACO/278-605             .....................................................................................................................................INVTAGADAIMDKVSQFQQIQDIVGESGTNVGGMLEAVRQTMADLTGK......TNSDIQIQDLLAVDTQVPVK.........VRGGLAGEFSNESAVGIAAMVKSDHLQ...MQVIADLIESEL......HTK.VEIGG..A..EAE.A.AIRGALTTPGT.T.K.PIAILDLGAGSTDASIIDKDNNI..VA..I.HL.A.G..A..G....D....M....VT....MIIN..S......E..L....G......LD.D.....RNLAEDIK.K.YPLAKVDNLFQLRHEDGSVQFFE.DPLPAELFARVVVI.EP.DGYQPL..PGKLNIERVRFVRRTAKRRVFVTNAQRALAHV..SPTGNVRDI.PFVVIVGGSALDFEIPQLVTDQLAQYNLVSGRGNIRATEGPRNAVATGLILG-y.................................................................................................
I9LEU7_9FIRM/275-602                 .....................................................................................................................................IDVESGAGKIMETVERVQPVLDVQGEAGTHVSGMLERVRQVMSELTKQ......HLGDMKIQDILAVDTFVPQK.........VQGGLAGEFALENAVALAAMVKTSRLP...MEQIANQLRSNL......GVD.VVIAG..V..EAN.M.AIRGALTTPGT.D.K.PLAILDMGGGSTDAAIITRDERV..LS..I.HL.A.G..A..G....D....M....VT....MLIN..S......E..L....G......LN.D.....FDLAEDIK.K.YPLAKVESLYHIRLEDGTVRFYE.QHLPPQVFSRVVIL.KD.GEMVPI..PSSHPLDKIRHVRREAKKRVFVTNAIRSLSRV..APTGNIRHI.EFVVLVGGSAMDFEVGDMVTDALAEYSIVCGRGNIRGSEGSRNAVATGLVLSY..................................................................................................
C6JP61_FUSVA/274-601                 .....................................................................................................................................IEVDKGAEPIMEALEACFPINDIWGETGTNAGGMLEKVRIVMAQLTDQ......DPKDIKIQDLLAVNTFVPKK.........VKGGIAEEFSMENAIGLAAMVKADRLQ...MERIALDLQEKL......GKS.VVVGG..V..EAE.M.AIIGALTTPGT.N.K.PLAIIDMGAGSTDASVITREGRI..SS..C.HL.A.G..A..G....N....M....VT....MLID..K......E..L....G......LD.N.....FDLAEDIK.K.YPLAKVESLFHIRHEDGSVEFFE.DTLDPRTFARVVIL.KE.GKMIPL..DIDEPIEKIKKVRRDAKEKVFVVNAVRALKKV..SPSGNIRDI.DHVVLVGGSALDFEVPQMVTDKLSYYGVVAGRGNIRGTEGPRNAVATGLALSY..................................................................................................
A0A0M2U968_9FIRM/274-601             .....................................................................................................................................VDLEEGADAIMEAMEKVKPLQDASGTPGTNVGGMLERVRQVMSDLTKQ......DRDQIRIQDILAVNTFVPQK.........VRGGLAGEFSSEDAVAMAAMVRTSRLP...MQEIALKLGQET......GVR.VEIAG..V..EAH.M.AILGALTTPGT.S.R.PLAILDLGGGSSDAAVIGRDGQI..NA..V.HL.A.G..A..G....D....M....VT....MLIA..S......E..L....G......LE.D.....RSVAEDIK.R.HPAAKVESLFHLRLEDGTVRFFE.EPLDSRLFARVVIL.KE.HDMIPV..PGRHSLEKVRTVRRDAKRKVFVTNAIRALAQV..APAGNLRLI.DFVVMVGGSALDFEIADLLSDALAAYGVVAGRGNIRGSEGPRNAVATGLVLSY..................................................................................................
A0A0F2Q594_9CLOT/275-603             .....................................................................................................................................VDIEEGSEVIMSIVKKITPLNDVHGESGSNVGGMIEKVRNVMSNLTNQ......PRGQMKIQDILAVDTIVPQK.........VTGGLAGEFSLENAVGLAAMVKTNRLP...MEQIAEKLAKEL......GIE.TVIAG..V..EAN.M.ALLGALTTPGT.A.K.PLAILDLGGGSSDAAIITNNNKT..SS..V.HL.A.G..A..G....D....M....VT....MLIN..T......E..L....G......LE.N.....LHLAEEIK.K.YPLGKVESLFHVRLEDGTVKFFD.KSLPPQFFARTVII.KGqDDMVPI..QAKHSLEKIRAVRREAKHKVFVINAVRALEQI..SLTGNIRYI.QYVVLVGGSALDFEIPEMISNALAGYGIVCGQGNVRGMEGPRNAVATGLVLS-i.................................................................................................
D1AFL7_SEBTE/275-602                 ...................................................................................................................................ag--IEEGAERIMTGVESVQCVTDVRGEPGTNVGGMLEKVRQTMASLTKK......LPSDIYIQDLLAVDTFVPVN.........IKGGLANEFSMENAVGIASMVKSDRLQ...MQIIAEELEKEL......GVK.VEIGG..V..EAN.M.AIMGALTTPGT.D.S.PLAIVDMGAGSTDASIIDRQGRI..FS..V.HL.A.G..A..G....N....M....VT....MLIN..S......E..L....G......LA.D.....TGLAEDIK.I.YPLAKAESLFHIRHEDGTVQFFK.EALKPEVFARVVVL.KE.DEMLPV..PGEHSLEKIKAVRRSAKERVFVKNAIRALEFV..SPTGNIRDI.PFVIMVGGSALDFEIPELVTDRLAKYSIVAGRGNIRETEGPRNAVATGLILD-i.................................................................................................
A6TDD5_KLEP7/275-602                 .....................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVAGEAGTNIGGMLEHVRQTMAELTNK......PAQEIRIQDLLAVDTAVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MALIAREIEHKL......QIA.VQVGG..A..EAE.A.AILGALTTPGT.T.R.PLAILDLGAGSTDASIINAQGEI..SA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.SALPPAVFARVCVV.KP.DELVPL..PGDLPLEKVRAIRRSAKSRVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYRLVAGRGNIRGCEGPRNAVASGLLLSW..................................................................................................
A5VMA9_LACRD/278-605                 .....................................................................................................................................VGVSEGADAIMKKVSSFRHINNITGESGTNVGGMLENVRQTMADLTGK......KNDEIAIQDLLAVDTQVPVE.........VRGGLAGEFSNESAVGIAAMVKSDHLQ...MEVIAKLIEKEF......NTK.VEIGG..A..EVE.S.AIRGALTTPGT.D.K.PIAILDLGAGSTDASIINKENNT..VA..I.HL.A.G..A..G....D....M....VT....MIIN..S......E..L....G......LN.D.....IHLAEDIK.R.YPLAKVENLFQIRHEDGSVQFFK.DPLPSSLFAKVVVI.KP.DGYEPV..TGNPSIEKIKLVRQSAKKRVFVTNALRALKYV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELAHFNLVAGRGNVRGVEGPRNAVATGLILRY..................................................................................................
I4BU32_ANAMD/277-605                 .....................................................................................................................................INIDEGAKAIMEMVESSWPIQDIFGQPGTNVGGMMERVRKTMSELTSL......PLGEIHIKDLLAVDTMVPQR.........VVGGLAEEFAMENGVALAVMVEAQELP...MQRLASAIESEI......GVK.AEIGG..V..EAE.M.AIMGALTTPGT.S.T.PLAVLDLGAGSTDASLMRPNGQV..EL..I.HL.A.G..A..G....N....M....VN....TIIA..S......E..L....G......LD.D.....MELVENIK.M.HPLCKVESVFHVRLEDGTVRFFD.KPLAPELFGRVALIiSE.DFLSPI..LLDASIEKIRDVRRKAKREVFVTNATRALKRV..APAQNIRLI.DFVVLVGGSALDFEIPNMITEELSKYSVVAGRGNIRGTLGPRNAVATGLVLS-t.................................................................................................
A0R5U9_MYCS2/262-565                 .....................................................................................................................................VEFARDGEQVRYPPAQAHTI--LRREPPGSVVRI--RLRSVPTADHEM......AVDDAFFTDLAALDNGTWLRrgvadasgtVVALLAADHVADAAATLAELT------...------------......GRP.ARTLA..S..EPE.A.AARGARTTPGL.P.P.DSVVCDIGGGTID--LVGAERTV..TA..-.--.A.G..A..G....E....T....IT....VAVA..K......M..L....G......I-.P.....RALAERVK.R.TPAIRVEGPHVAHEEDGRRLFLD.APAPAEAIGRLCTR.GT.AGLVPF..SSRLAAEEWRSLRLAIKQETVAANIARCMKAFekPPTA-----.--LVLAGGGALDDELLRTVGESLRTAGVVVGRANIDGVHGPRFAVASGLVHLY..................................................................................................
R5BN42_9FIRM/275-602                 .....................................................................................................................................IDISAGAEQIMATLGQVSHIDNVCGEAGTNVGGMLERVRQTMADLTNK......SPNDVFIEDLLAVDTSVPIN.........VKGGLAGEFSMEQAVGIASMVKSDHLQ...MEIIAKEVEREL......KIP.VEIGG..Q..EAE.S.AILGALTTPGT.E.T.PLAILDLGAGSTDASIMSPDGRV..TA..I.HL.A.G..A..G....N....M....VT....MLIN..S......E..L....G......LE.D.....IHLAESIK.K.FPLAKVISVYHIRHEDGNVQFFK.DPLPADLFAKTVIV.TD.EGLVPI..EGDQSMEKIKIVRQTAKERVFVTNSLRALRAV..SPTHNVRDI.PFVVIVGGSALDFEVPQLVTDALSHYNLVAGRGNVRGTEGARNAVATGLILSY..................................................................................................
D2Z8G8_9BACT/278-606                 .....................................................................................................................................VDVEAGAEAIMNLLSVCHPITDIFGQPGTNVGGMMERVRTTMAKLTGL......SIAEIHIQDLLAVDTMVPQK.........VVGGLAGEFSQENGVALAVMVKTAKLP...MQAVAEAVSEDI......GIK.VEIGG..V..EAD.M.AIRGALTTPGT.D.R.PIAILDLGAGSSDASFMKYDGSV..EL..I.HL.A.G..A..G....N....M....VN....TVIC..S......E..L....G......IE.D.....PELAESIK.R.YPLCKVESAYHVRQEDGTVRFFD.RPLAPDLFGRVALA.ISdDILQPI..PLRVSMEKVRMVRRKAKKEVFVTNALRALEHV..APAGNVRMI.DHVVLVGGSAKDFEIPTMVTDALARYGVVSGRGNVRGSEGPRNAVATGLVLSY..................................................................................................
E3CVA2_9BACT/277-605                 .....................................................................................................................................VNVEDGAEAIQTTVAASAPVENIFGQPGTHVGGMMERVRRTMSDLTGI......PLGEVSIRDLLAVDTLVPQK.........VVGGVAGEFSLESGVALAVMVKTEELP...MQRLAEAVSADL......GVP.VEVGG..V..EAD.M.AIRGALTTPGT.K.R.PLAVLDLGAGSSDASFMKEDGTV..DL..V.HL.A.G..A..G....N....M....VN....TILA..S......E..L....G......IE.D.....PDLAESIK.R.YPLCKAESAFHIRQEDGTVRFFD.APLDPQVFGRVALL.HEnDLLQPI..PLPVTLEKVRAARRKAKKEVFVTNALRALEQV..APAGNVRML.DHVVLVGGSASDFEVPTLITEALSRYGIVAGRGNIRGKEGPRNAVATGLVLS-a.................................................................................................
A9MLQ0_SALAR/275-602                 .....................................................................................................................................IDVAAGADAIMKAVSNCPQLDNVTGEAGTNIGGMLEHVRQTMAELTNK......PSAEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIAREIEQKL......SID.VQVGG..A..EAE.A.AILGALTTPGT.T.R.PLAILDLGAGSTDASIINPKGEI..IA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LN.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.APLPPEVFARVCVV.KP.DELVPL..PGDIALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSALDFEVPQLVTDALAHYRLVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
Q8XLV8_CLOPE/280-607                 .....................................................................................................................................VDVEEGADKIMEAVSLCSPIEDLRGDAGSNVGGMLEKVRQVMADLTNQ......SISDIKIQDLLAVDTFIPQK.........VKGGLAKEFSMENAVGIAAMVKAHKLQ...MQIIANKLEEKL......GVP.VEVGG..V..EAD.M.AIRGALTTPGT.N.T.PLAILDMGAGSTDASIINKEGKI..TS..I.HL.A.G..A..G....N....M....VT....MLIK..S......E..L....G......IE.D.....FGLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.KPLDSSVFAKIVII.KE.GMLIPV..DGQNSLEKIKNVRKTAKERVFVINCLRALKSV..SPTGNIRDI.EFVVLVGGSSLDFEVPELVTDALSHYGVVAGRGNIRGCEGPRNAVATGLVLA-f.................................................................................................
G9YVN8_9FIRM/274-601                 .....................................................................................................................................VDVDDGADKIMKAVESIPSLEDVRGEPGTNAGGMLEKVRQVMANLTSQ......HPRDIKIQDLLAVDTFTPQK.........VQGGLANEFSQENAVGIAAMVKADRLQ...MEAIAREFAQQI......GVP.VEVGG..V..EAD.M.AIRGALTTPGT.N.K.PLAILDMGAGSTDASIINAEGQI..HS..I.HL.A.G..A..G....N....M....VT....LLIQ..S......E..M....G......LP.D.....FDTAEDVK.K.YPLAKVESLFHIRHENGTVEFFQ.QPLDPNLFAKVVIL.KE.GKLLPL..EGDWSMEKIRLIRQQAKQKVFVTNAIRALTRV..SPTGNVRDI.QFVVLVGGSALDFEVPQMVTDALSQYKVVAGRGNIRGTEGPRNAVATGLVLS-l.................................................................................................
V5X9M2_MYCNE/272-605                 .....................................................................................................................................IDVSRGAAEIMAEVERVSPLQDVLGESGTNTGGMIANVRQSMADLSKH......ALADVRIKDLLAIDTLVPQE.........VRGGVAGEVALENAVALAAMVRTKESG...MQAVADAVATALrdagatRIS.AVVGG..V..EAE.M.AVLGALTTPGT.E.K.PLVVLDMGGGSTDAAVIERSGDV..QA..V.HL.A.G..A..G....D....L....VT....KLID..A......E..L....G......LD.N.....LELAEDIK.R.LPLGKAESFFHVRLENGTVQFFD.KPLPPNAFARVVTL.SE.MGMSPI..PTRHSLDRIRTVRRTAKERVFVVNALRALRAV..APHGDLRQI.GFVVLLGGCALDFEIPELIADAVAPYGIVCGTGNVRGTEGPRNAVASGLVASY..................................................................................................
R6G9W5_9FIRM/273-601                 .....................................................................................................................................VDVDEGADKIMEAISSIQEIDDIQGETGTNVGNMLNKVRRVMAGLTNK......SPQDIKIQDLLAVDTFNPQK.........VVGGIADEFALENAVGIAAMVKSDRLQ...MEMIAQVLTEKL......RVP.VYVGG..V..EAD.M.AIKGALTTPGT.S.V.PLAIVDMGAGSTDASIINREGKV..KL..I.HL.A.G..A..G....N....M....VS....LLIQ..S......E..L....G......LD.D.....FELAEDVK.K.YTLAKVESLFHIRHENGTVQFFD.KPLDPSIFAKVVLV.KEnDELVPL..DGVESLEKVKAVRMEAKKKVFVTNAIRSLSKV..SPTGNPRDI.QFVVMVGGSALDFEIPNFVTDALADYEIVAGRGNIRGCEGPRNAVATGLAMA-c.................................................................................................
A0A0H3J8Q7_CLOPA/275-602             .....................................................................................................................................VDVEDGASKIMEVVKSTVSIEDIKGESGTNVGGMFERVRQVMSKLTNQ......DFQSIKIQDILAVDTFVPQK.........IVGGLAREFSLENAVGIAAMVKADKLQ...MQIIADELKNKL......SVE.VEIGG..V..EAE.M.AILGALTTPGS.N.K.PLAILDMGAGSTDASIINKNGEI..SS..V.HL.A.G..A..G....N....M....VT....MLIN..S......E..L....G......LN.S.....FDLAEDIK.R.YPLAKVESLFHIRHEDGTVEFFE.EHFDPSIFARTVIL.KE.GNLIPI..NIEASIEKIKMIRKMAKEKVFVTNCIRALSIV..SPTGSIRDI.EFVVLVGGSSLDFQVPQLITDALSKYGVVAGRGNIRGLEGPRNAVATGLILD-i.................................................................................................
E4RMA0_HALHG/276-603                 .....................................................................................................................................IGIDAGAEEIMDSLEKIHPIEDVKGQPGTNVGGMLDRVKVTMSKVTDQ......PLEDIRIKDILAVNTFVPKE.........VKGGLAEEYAMENAVGLAAMVKTSQLP...MRKIADKLEDET......NVE.VEIAG..V..EAN.M.AILGALTTPGT.D.K.PFVILDMGGGSTDAAMVTNRDNI..YT..T.HL.A.G..A..G....D....M....TS....LLIN..I......E..L....G......LG.D.....INLAELIK.K.NPLAKVESVFHVRHEDGSVSFFD.EPLAPKLFGRVIIL.SD.DDKIPI..PTDHSLDKIRQVRRDAKNDVFVRNSIRALKRI..IPTGNIRDI.DFVVMVGGSAIDFEIPTMISNQLSEYGVVAGRGNIRGVMGPRNAVATGLVLSY..................................................................................................
I6GPC4_SHIFL/273-600                 ....................................................................................................................................a-DVAQGAQAIMQAMSACAPVCDIRGEAGTHAGGMLERVRKVMASLSGH......DMNAVHIQDLLAVDTFIPRK.........VQGGIAGECSMENAVGIAAMVKSDRLQ...MQAIASELSARL......NTA.VEVGG..V..EAN.M.AVTGALTTPGC.A.A.PLAILDLGAGSTDAAIINSEGAV..KA..V.HL.A.G..A..G....N....M....VS....LLIQ..T......E..L....G......LS.D.....PFLAEEIK.K.YPLAKVESLFSIRHENGVVEFFR.EPLSPSVFAKVVYL.KD.GELIPV..DNQTSLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.TFVVLVGGSSLDFEIPQMITDALAHYGVVAGQGNIRGTEGPRNAVATGLVLA-g.................................................................................................
R5RU48_9FIRM/273-600                 .....................................................................................................................................VSIDAGGVKIMKSLQKAGDILDIVGQPETNVGNMFHNIRENMAKVSGE......TKEKIRITDLLAVDTMAPVE.........ISGSLAGETCMEKAVGIAAMVKTHHLP...MEQIAEKLEEEL......HLK.GKVAG..V..EAV.M.ASLGALTTPGT.Q.L.PLAILDMGGGSTDAALLDADGTV..KT..T.HQ.A.G..A..G....E....L....VS....MLIQ..T......E..L....G......FK.S.....RATAEQIK.K.YPLAKVESLFHMRLENGAMEFFQ.DSIDPRYYGHVVLL.AP.GELLKI..EEDIPMERIRQVRREAKEKVFVTNALRALEKV..APEHNLKNI.SNVVLVGGSAEDFEIPEMLTQILAEYRIVCGRGNIRGQEGPRNAVATGLLLS-s.................................................................................................
E3H9G3_ILYPC/274-601                 .....................................................................................................................................VNIEEGSKRIMKALGSIEHVQDINGESGTNIGGMLKNVKSVMGNFTNE......SIDNIKIKDILAVDTFVPQK.........IKGGIAEEFVFENAVGIAAMVNTKKNQ...MSEVAKEIEKEL......GVK.VEVGG..V..EAD.M.AITGALTTPGT.G.T.PLVIVDIGAGSTDACSIDRYGNK..EL..V.HL.A.G..A..G....N....M....TT....LLIQ..K......E..L....G......IE.D.....FNLAEDIK.K.YPLAKVESLFYIRHEDGNVQFFE.NSLSPKVFAKNVLI.KE.GELIPI..DLDMSLEKIRIIRRSAKRKIFITNVLRSLRKV..SHTKNIRDF.EFVVIVGGSALDFEISQMITEALSEYGIVAGCGNIRGTEGPRNAVATGLVM--gv................................................................................................
A0A0F3RTY4_9LACO/276-603             .....................................................................................................................................VNVAAGAEAIMKKINEFDRIQDITGESGTNVGGMLEKVRQTMADLTAK......QNREIAIQDLLAVNTSVPVK.........VRGGLAGEFSTEEAVGIAAMVKSDHLQ...MQLIANLIQDEL......NIP.VEIGG..A..EAE.A.AILGALTTPGT.T.K.PIAILDLGAGSTDASIINKQNQI..VA..I.HL.A.G..A..G....D....M....VT....MIIN..S......E..L....G......LD.D.....VYLAEDIK.K.YPLARVENLFQIRHEDGSVQFFD.KPLPSEIFARTVVI.KP.DGYVPL..PGNLNIEKVKTIRQTAKKRVFVENAQRALKHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYNLVAGRGNIRSVEGPRNAVATGLILSY..................................................................................................
I3VRW4_THESW/275-603                 .....................................................................................................................................VSVDSGAEAIMESVEEVGTIDDVEGEENTNVGNMIKNLKNKMANITGQ......KVDKIKIKDIFAVDTTVPVK.........VEGGLAGETSMEKAVVLAAMVKTDTLP...MIEIAEKLQRKL......GVF.VKIAG..V..EAV.M.ATLGALTTPGT.K.L.PLAILDIGGGSTDAALIDEKGIV..KS..I.HM.A.G..A..G....E....L....VT....MLID..S......E..L....G......LN.D.....RYLSEEIK.R.NPIGKVESLFHIRMENREIKFFD.KPLNPRYYGRIVIL.KE.NDMIPV.fKEDLTMEKIIYVRRQAKDKVFVKNAIRALKKI..APENNLRRI.PNVVLVGGSALDFEIPEMILSELSKYKIIAGRGNIRKIEGPRNAVATGLVMSY..................................................................................................
J2IRT7_9ENTR/273-600                 ....................................................................................................................................a-DVAQGAQAIMQAMSACAPVCDIRGEAGTHAGGMLERVRKVMASLTGH......EMSAIYIQDLLAVDTFIPRK.........VQGGMAGECAMENAVGMAAMVKADRLQ...MQVIARELSARL......QTE.VVVGG..V..EAN.M.AIAGALTTPGC.A.A.PLAILDLGAGSTDAAIVNAEGQI..TA..V.HL.A.G..A..G....N....M....VS....LLIK..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYGVVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
F0Z327_9CLOT/273-600                 .....................................................................................................................................VNLDEGAEKIMQAVSDAGSIRDISGQPNTNVGNMLSRIKQGMGELDNT......PDADIHITDVLAVDTLAPVL.........ISGALAGETCLEKAVGIAAMVKTRQLP...MREIAEKLKLEL......GTD.VKVAG..V..EAV.M.ASLGALTTPGT.Q.L.PLAILDMGGGSTDAAVISEEGQV..TM..T.HQ.A.G..A..G....E....L....VS....MLIE..T......E..L....G......LG.D.....RHMAEQIK.K.YPLAKVESLFHMRMENGQMTFVE.DSIDPRFYGRVILL.AE.DGFIRM..EKDIPMEKIVQVRRDAKRKVFVTNAFRALKKV..APGHDLRNI.SNVVLVGGSAEDFEIPEMLMEEFAGYRIVCGRGNIRGAEGPRNAVATGLVLSY..................................................................................................
Q03Q33_LACBA/276-603                 .....................................................................................................................................VNVAAGAEAIMKKVNQFDRIQDITGEAGTNVGGMLEKVRQTMADLTNK......QNRDIAIQDLLAVNTAVPVK.........VQGGLAGEFSTEQAVGIAAMVKSDHLQ...MQQIADLIQDEL......HIS.VEIGG..A..EAE.A.AILGALTTPGT.T.K.PIAILDLGAGSTDASIINQQDDI..VA..I.HL.A.G..A..G....D....M....VT....MIIN..S......E..L....G......LD.D.....VYLAEDIK.K.YPLARVENLFQIRHEDGTVQFFE.DPLPADIFARTVVI.KP.DGYVPL..PGNMNIEKVKQIRQTAKKRVFVENARRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYNLVAGRGNIRAVEGPRNAVATGLILSY..................................................................................................
G8PEJ6_PEDCP/276-603                 .....................................................................................................................................VNVATGATEIMKHINNFDQITDISGEAGTNVGGMLEKVRQTMAELTGK......QNKDIAIQDLLAVDTSVPVR.........VQGGLAGEFSTEQAVGIAAMVKSDHLQ...MQRIADLIQSEL......HID.VEIGG..A..EAE.A.AILGALTTPGT.T.K.PIAILDLGAGSTDASIINQKDEI..VA..I.HL.A.G..A..G....D....M....TT....MIIN..S......E..L....G......LN.D.....VYLAEDIK.K.YPLAKVENLFQIRHEDGTVQFFD.QPLPSEIFARVVVI.KE.DGYIPV..PGNMSIEKIKTVRQTAKKRVFVENARRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYNLVAGRGNIRSVEGPRNAVATGLILSY..................................................................................................
F9ELP3_FUSNU/274-601                 .....................................................................................................................................VSLDNGAEAIMSVLEQCYPVIDIWGEKGTNAGGMLERVRIVMAQLTNQ......DPKNIKIQDLLAVNTFVPQK.........VKGGIAEEFSMENAIGLAAMVKADKLQ...MEMIATELQNKI......NKK.VVVGG..V..EAE.M.AIIGALTTPGT.A.K.PLAIIDMGAGSTDASIMTADNKI..SS..C.HL.A.G..A..G....N....M....VT....MLID..K......E..L....G......IN.N.....IELSEDIK.K.YPLAKVESLFHIRHEDGSVQFFE.EALDPRVFARIVIL.KE.GNMIPL..DSNQNLEKIKNVRREAKEKVFVTNTLRALKKV..IPSGNVRDI.DYVVLVGGSALDFEIPQMVTEALSHFGVVAGKGNIRGVEGPRNAVATGLALSY..................................................................................................
B8FDN6_DESAA/272-599                 .....................................................................................................................................VDVELGADAIMEKLARVAPLKEIQSQPGTNAHGMFERVRTVMAELTDQ......PVSLIKIQDVLAVNTLQPQH.........VLGGLAGEFTRGTAVGLAAMVMTQNIP...MQRLAAKLKEET......GVE.VEIGG..V..EAE.M.AITGALTTPGA.E.A.PLAILDLGGGSTDASIIHRDGTV..KS..I.HM.A.G..A..G....D....M....VT....MLIN..T......E..L....G......LD.D.....PDLAEDIK.R.YPLAKVETLFHMRHETGAVEFFD.AHLDPSLFGRVAIL.GE.NGPIPI..MHDLNLNQIVNVRRKAKEKVFVRNALRALEQV..APGGNIRLI.DFVALVGGSALDFEIPEMIADALAEYGPVLGKGNIRGCEGPRNAVATGLCLS-r.................................................................................................
R5XK30_9FIRM/273-600                 .....................................................................................................................................VNIDTGADSIMETLQKAGQIRDISGQQNTNVGNMLDRIKKSMTDVASD......RDQEVRITDILAVDTLAPVE.........ISGSLAGETCMEKAVGIAAMVKTKHLP...MQKIAEKLEQEL......KVK.AVVAG..V..EAV.M.ASLGALTTPGT.R.L.PLAILDMGGGSTDAAVLEENGTV..RT..T.HQ.A.G..A..G....E....L....VT....MLIQ..T......E..L....G......LG.S.....RTTAEQIK.K.YPMGKVESLFHMRLENGSMQFFE.ESIDPGYYGHVVLL.AP.GEMLKV..EEDIPMEKILEVRREAKRKVFVRNAVRALKIV..APEHDLRKI.SNVVLVGGSAEDFEIPEMLTEALAEYRIVCGRGNIRGTEGPRNAVATGLLMSY..................................................................................................
A0A0D1VHX9_ANEMI/276-603             .....................................................................................................................................VAINDGAEEIMRSIERAGGLINVQGEMGTNVGGMLNGLRQYLSESTGQ......PFADISIGDLLATDVLIPVS.........VSGAMAGELSMESGVALASMVKTERMP...VERVAQALEKEL......GIP.VEVGG..V..EAE.M.AIRGALTTPGT.E.K.PLVILDMGGGSTDAAAVSEGGET..IS..V.HL.A.G..A..G....D....M....VT....MLID..A......E..L....A......LH.S.....RELAEKVK.K.NPLGKVMSLFHMQLEDGTMLFSE.SPFPPDVYGRVVIR.EE.KELVPL..PVKLSMEKVRAVRRSAKRRVFVTNAIRALAYI..VPTKNIRHL.SFVVMVGGSALDFEIPQMVTEELGKYGIVAGFANVRGTEGPRNAVATGLVLS-v.................................................................................................
C4LFD2_TOLAT/275-602                 .....................................................................................................................................VDVASGSEKIMQAVKACRQLDNVTGESGSNIGGMLENVRQTMAELTNK......PSGEIFIQDLLAVDTFVPVN.........VQGGLAGEFSLEQAVGIASMVKSDHLQ...MARIAEEIHNTL......HIG.VQIGG..A..EAE.A.AILGALTTPGT.T.K.PMAILDLGAGSTDASIINPQGEI..VA..T.HL.A.G..A..G....D....M....VT....MIIA..S......E..L....G......LE.D.....RYLAEDIK.K.YPLAKVESLFHIRHEDGSVQFFD.SPLPAAVFARVVVV.KE.GKFIPL..PGEFALEKVRNIRRSAKERVFVANSLRALQFV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALSHYNLVAGRGNIRGCEGPRNAVATGLILSY..................................................................................................
A0A0M3DJ14_9CLOT/278-605             .....................................................................................................................................VDVEHGAKNIMDAVGLCVPIQDVKGEPGTNAGGMLERVRQVMANLTKQ......KIADITIQDLLAVDTFIPQK.........VKGGIAEEFSMENAVGIAAMVKADKLQ...MQMIADKLQEKL......GVL.VEVGG..V..EAD.M.AIRGALTTPGS.S.T.PLAILDMGAGSTDASIINKQGEI..CS..I.HL.A.G..A..G....N....M....VT....MLIK..S......E..L....G......LE.D.....FTLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.KSLDSSVFAKVVIL.KN.GEIVPI..EGQNSIEKIKNIRKSAKEKVFVTNCIRALTIV..SPTGNIRDI.EFVVLVGGSSLDFEVPQLVTNSLSQYGVVAGRGNIRGTEGPRNAVATGLVLA-f.................................................................................................
S2WWZ2_9ACTN/274-601                 .....................................................................................................................................VDVDNGAEKIMAALGEVTDVTDITGEPGTNVGGMMEQVRVSMGTLTDQ......NPKDIKITDLLAIDTRTPKQ.........VAGGIANEFSMEAAVGIAVMVHADRLQ...MQMIADEISAEI......GIP.VEVGG..V..EAD.M.AIQGALTTPGV.A.A.PIAVLDMGAGSTDASVMHADGSI..VS..T.HL.A.G..A..G....N....M....VT....LMIK..T......E..L....G......LS.D.....THIAEDIK.R.YPLAKVETIFSIRHEDGTVQFFN.DPLPPETFARVVIM.KP.DGLVPL..DIDLPVETIRQVRIRAKQQVFVTNAVRALRKV..SPTENVRDI.DFVVLVGGSALDFEIPQLVTHALADYRVVAGRANIRGSEGPRNAVATGLALSW..................................................................................................
O31043_SALTY/275-602                 .....................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVTGEAGTNIGGMLEHVRQTMAELTNK......PSSEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIAREIEQKL......NID.VQIGG..A..EAE.A.AILGALTTPGT.T.R.PLAILDLGAGSTDASIINPKGEI..IA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPAVFARVCVV.KP.DELVPL..PGDLALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYRLVAGRGNIRGSEGPRNAVATGLILSW..................................................................................................
A8AEN2_CITK8/275-602                 .....................................................................................................................................VDVAAGAEAIMKAVGECRKLDNVTGEAGTNIGGMLEHVRQTMAELTNK......PSNEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIAREIKQKL......SVD.VQVGG..A..EAE.A.AILGALTTPGT.T.R.PLAILDLGAGSTDASIINPKGEI..IA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LD.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPAVFARVCVV.KP.DELVPL..PGDLALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYRLVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
G2G2A6_9FIRM/275-602                 .....................................................................................................................................IEVDAGAAKIMETVERVQPVLDVQGEAGTNVSGMLERVRQVMSELTAQ......PLGEMKIQDVLAVDTFIPKK.........VQGGLAGEFALENAVALAAMVKTSRLP...MQQIADQLMQSL......GLR.VVIAG..V..EAG.M.AIHGAFTTPGT.A.K.PLAILDMGGGSTDAAIITRDEQV..LS..I.HL.A.G..A..G....D....M....VT....MLIN..S......E..L....G......LN.D.....FNLAEDIK.K.YPLAKVESLFHIRLEDGTVQFYE.HHLPPEVFSRVVIL.KD.GEMVPI..PTNHPLDKVRHVRRESKKRVFVINSLRSLARV..APTGNIRHI.DFVVLVGGSALDFEVADMVTDALAEYGIVCGRGNIRGSEGPRNAVATGLVLSY..................................................................................................
A0A090U426_9ENTR/273-600             ....................................................................................................................................a-DVAQGAQAIMQAMSACAPVCDIRGEAGTHAGGMLERVRKVMASLTGH......DMNAVHIQDLLAVDTFIPRA.........VQGGIAGECSMENAVGIAAMVKSDRLQ...MQAIASELSARL......NTP.VEVGG..V..EAN.M.AVAGALTTPGC.A.A.PLAILDLGAGSTDAAIINSDGVV..KA..V.HL.A.G..A..G....N....M....VS....LLIQ..T......E..L....G......LS.D.....PFLAEEIK.K.YPLAKVESLFSIRHENGAVEFFR.EPLSPSVFAKVVYL.KE.GELIPV..DNQTSLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.TFVVLVGGSSLDFEIPQTLTDALAQYGVVAGQGNIRGTEGPRNAVATGLVLA-g.................................................................................................
A0A0E3MC80_CLOSL/272-599             .....................................................................................................................................VSIEEGSEGIMKNLGEVWPLNDVSGESGTNVGGMIERVRQIMGELTSQ......NIEDIKIQDILAVDTFKPQK.........VQGGLAGEFALENAVALAAMVKTSKLP...MENIARKLQEST......GIK.VVIGG..V..EAN.M.AVLGALTTPGT.D.K.PLVILDMGGGSTDSAYISKEGKV..KS..I.HH.A.G..A..G....E....M....VT....MFIN..S......E..L....G......LE.D.....YNLSEDIK.K.YPLAKVESLFNLRYEDGTVCFFQ.QPLDASLFARNVVV.KN.DEMIPI..PTKDSLEKIRLVRRDAKKKVFVTNAIRALRDT..APNGNLRSI.EFVVLVGGSALDFEIPEMVSEELSHYGIVCGSGNIRGIEGPRNAVATGLVLSY..................................................................................................
H6LEQ0_ACEWD/273-600                 .....................................................................................................................................VNVDDGAEKIMEAIRTVAPIEDIKGEAGTNAGGMLEKVRQVMSNLTDQ......LPSAIKIQDLLAVDTFVPQT.........VKGGIAEEFSMENAVGIAAMVKADKLQ...MNMIAHELEAEL......GVK.VEVGG..V..EAD.M.AIRGALTTPGS.N.T.PLAIIDMGAGSTDAAIINKAGEI..KS..I.HL.A.G..A..G....N....M....VT....LLIA..S......E..L....G......YD.N.....MALAEDIK.K.YPLAKVESLFHIRHEDGTVQFFD.KPLDPRTFARVVIL.TP.NGMIPM..PGNYSLERIRAIRREAKTKVFVVNALRSLERV..SPTGNVRDI.EFVTLVGGSALDFEIPQLVTDALAKYSIVSGRANIRGVEGPRNAVATGLVLAY..................................................................................................
E6MIY1_9FIRM/273-600                 .....................................................................................................................................IDVDAGADEIMEAVRTVAPIGDVTGEPGTNAGGMLERVRQVMSNLTKQ......TPDKILIQDILAVDTFVPKR.........VQGGMANEFSMENAVGIAAMVRADKLQ...MGMIADELEKEL......GIK.VEVGG..V..EAE.M.AIHGALTTPGA.N.K.PMAILDMGAGSTDAAIINRAGEI..HF..I.HL.A.G..A..G....N....M....VT....MLIG..S......E..L....G......LD.D.....RGIAEDLK.K.YPVARVESLFHIRHEDGSVQFFD.SPLDPRTFARTVIL.TP.NGMSPL..PGDITVERVRQVRQDAKRKVFVVNAIRALERV..SPTGNARDI.EFVTMVGGSALDFEVPQLITDALSRYSIVAGRANIRATEGPRNAVATGLVLAY..................................................................................................
A1UN21_MYCSK/264-567                 .....................................................................................................................................VDCRIGGEIVRYAPAAAHTV--LRLEPPGCAVEV--RLSALPAAENGI......AVDDAFFTDLASIDNGAWLRrgvadargtVVALLAAEPVTDAAATLSGLT------...------------......GRP.ARTVA..G..EPA.A.AARGAQTTPGL.P.P.GSVVCDIGGGTVD--LIGQGRTV..TA..-.--.A.G..A..G....E....T....IT....TAVS..R......V..L....G......I-.P.....RALAERVK.R.TPALRVEGPHVAHEEDGRRVFLD.SPASADAIGRLCTR.GS.AGLVPF..SHRLAAEEWRSLRLAIKQQTVAANIARCLATFdePPS------.-ALVLAGGGALDDELLRTVGESLRPARVVVGRADIDGVHGPRFAVASGLVHLY..................................................................................................
R6EEW3_9FIRM/1-159                   .....................................................................................................................................------------------------------------------------......--------------------.........---------------------------...------------......---.-----..-..---.-.-----------.-.-.-----------------------..--..-.--.-.-..-..-....-....-....--....MLTE..T......D..L....G......RG.A.....RHMAEQIK.K.YPLAKVESLFHMRMENGQMTFVE.DSIDPRFYGRVVLL.AE.DGLIRI..EQDIPMEKIAAVRREAKRKVFVTNAFRALKKV..APGHDLRKI.SNVVLVGGSAEDFEIPEMLMEEFAGYRIVCGRGNVRGSEGPRNAVATGLVLSY..................................................................................................
A0A0M2K4E0_9MYCO/260-563             .....................................................................................................................................VEIHVDGATVRYTPAQAHAV--LRRSVPGSVKRV--RLQSVPSAADSL......AVHDAFFTDLATIDNGAWLRrgvvdahgtVVALLAAEEAADAAARLSELT------...------------......GRP.ARTLA..S..EPE.A.AAWGARTTPGF.P.P.DAMVCDIGGGTVD--LIGAEATV..VA..-.--.A.G..A..G....E....S....IT....VAIA..Q......V..L....G......I-.P.....QALAETVK.R.TPAIRVEGPHVAHEEDGRRVFLD.APASSDAIGRLCTR.GS.AGLVPF..SNRLAAEEWRSLRLAVKQETVAANIARCLTAFdePPR------.-ALVLAGGGALDDELMRTVAEALRPARVVVGRAHIDGVHGPRFAVARGLVA--lf................................................................................................
D2TPR1_CITRI/275-602                 .....................................................................................................................................VDVAAGADAIMKAVGDCPKLDNVTGEAGTNIGGMLEHVRQTMAELTNK......PSNEIFIQDLLAVDTAVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAMIASEIKEKL......NVD.VQVGG..A..EAE.A.AILGALTTPGT.T.C.PLAILDLGAGSTDASIINPQGDI..IA..T.HL.A.G..A..G....D....M....VT....MIIA..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.GPLPPTVFARVCVV.KP.DELVPL..PGDLPLEKVRAVRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYRLVAGRGNIRGVEGPRNAVATGLILSW..................................................................................................
H1LI38_9LACO/276-603                 .....................................................................................................................................VDVAAGAEAIMKTVNEFDSIDDITGKSGTNVGGMLEKVRQTMADLTGK......QNQDIAIQDLLAVNTSVPVK.........VTGGLAGEFSMEQAVGIAAMVKSDHLQ...MQIIANLIEQDL......HVP.VEIGG..A..EAE.A.AILGALTTPGT.S.K.PMAILDLGAGSTDASIINKEDKK..VA..I.HL.A.G..A..G....D....M....VT....MIIN..S......E..L....G......LD.D.....IYLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KPLPSNLFARVVAI.KP.VGYEPL..PGNLSIEKVKIVRQTAKKRVFVTNALRALRHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDALSHYNLVAGRGNIRSIEGPRNAVATGLILSY..................................................................................................
E3HDB0_ILYPC/274-601                 .....................................................................................................................................VRVDRGSKEIMSAIKACHPVNDIYGETGTNAGGMLEKVRVVMAQLTDQ......NVKNIKIQDLLAVDTFVPQK.........VVGGMAGEFAMENAIGVAAMVKADKLQ...MKMVASNLEEKL......DIA.VEVGG..V..EAE.M.AIIGSLTTPGT.T.K.PLAILDMGAGSTDASIITKSGEI..SS..C.HL.A.G..A..G....N....M....VT....MLID..R......E..L....G......LG.D.....FDLAEDIK.K.YPLAKVESLFHIRHEDGSVQFFD.TQLDPGIFARIVIL.KD.GEMQPL..EIDGNIEKIKNIRREAKKKVFVENGIRALVRI..SPTSNIRDI.DYVVLVGGSALDFEIPQMITDSLAHYGIVAGRGNIRGVEGPRNAVATGLSLSY..................................................................................................
F9DQU4_9BACL/277-604                 .....................................................................................................................................VDINDGADEIMGSYKNIGVLNDVQGEQGTNAGAMLNGLRQDLAEVTDQ......HMHEIRITDLLAVDTKIPSS.........IRGALAGEITMESGVGLASMVQTKKTS...IQAVSSLLEEEL......GVS.VEVGG..I..EAE.M.AIAGALTTPGT.E.R.PIVILDMGGGSTDAATNDENGRI..RT..V.HL.A.G..A..G....D....M....VT....LLIN..T......E..L....A......LH.D.....LELAEKIK.K.YPLGKLQSLYHMQLEDGTYLFSE.EPHPPEAFGKVVIR.EE.KGITPL..PIRHSLEKIRTIRREAKRKVFVTNAIRALEQV..LPTHNIRHI.SFVVMLGGSALDFEIPEMINDELSKYGIVAGFANIRGTEGPRNAVATGLVLS-t.................................................................................................
R6G8Y1_9FIRM/273-601                 .....................................................................................................................................VGVEEGAEKMMEAVNSVPVIEDIKGEPGTNAGGMLEKVRQVMSNLTNQ......HPKDIKIQDLLAVDTYNPQK.........IKGGLANEFSLESAVGIAAMVKADRLQ...MKMIAEELTDRL......KIP.VYVGG..V..EAD.M.AIKGALTTPGT.N.V.PLAIVDMGAGSTDASIKDRDGNV..KL..V.HL.A.G..A..G....N....M....VT....LLIQ..S......E..L....G......LE.D.....FNTAEDIK.K.YSLAKVESLFHIRHEDGTVQFFE.QPLDPNVFAKVVLV.KEdGELVPL..EGQDSMEKIKMVRTNAKKKVFVTNAIRSLAKV..SPTGNVRDI.EFVVLVGGSALDFEVPTLVTDALSQYNIVAGRGNIRGCEGPRNAVATGLAMS-c.................................................................................................
A0A0A7FXY5_9CLOT/279-606             .....................................................................................................................................VDVEHGASKIMDAVKLCVPIQDVKGEAGTNAGGMLERVRQVMANLTKQ......KITDIKIQDLLAVDTFIPQK.........VKGGLAEEFSLENAVGIAAMVKADKLQ...MQMIADELEKEL......KVP.VEVGG..V..EAD.M.AIRGALTTPGT.S.T.PLAILDMGAGSTDASIINKNNEI..SS..I.HL.A.G..A..G....N....M....VT....MLIK..S......E..L....G......LE.S.....FNLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.EPLDPSVFAKVVII.KD.GMLVPI..DGQTSIEKIRNIRRSAKEKVFVTNCLRALSIV..SPTGSIRDI.EFVVLVGGSSLDFEVPQLVTDALSQYGVVAGRGNIRGTEGPRNAVATGLILA-c.................................................................................................
D5XBU6_THEPJ/275-603                 .....................................................................................................................................VDIQAGAEKVQEVIESAGKLEDVRGEPGTNVGGMIERIRHVMSDLTNQ......PVHNMKIQDILAVDTFIPQK.........VQGALAGEFSLENAVGLAAMVKTNKLQ...MQEIAEKLAGEL......GIK.VEIAG..V..EAE.M.AVRGALTTPGS.D.R.PLAILDMGGGSTDAAIIDREGHI..NS..V.HL.A.G..A..G....D....M....VT....LLIN..S......E..L....G......LD.N.....PGLAEEIK.R.YPLAKVESLYHIRTEDGSVQFFD.KALDPRLFARVVIL.KEkGVMEPI..PVKDSLEKIKLIRQEAKKKVFVTNAVRALQRV..APHGNIRNV.EFVVMVGGSALDFEIPGFISDRLAEYGVVAGRGNIRGQAGPRNAVATGLVLSY..................................................................................................
D9S1P8_THEOJ/273-600                 .....................................................................................................................................VDLEEGADKVMQALEQVWPLVDVEGTPSTNVGGLIARVKEVMGQVTYQ......DMRKIKIQDILAVDVLVPQR.........VTGGIAEEFFTEDAVAVAAMVKSSKLP...MEKIAEKVEREL......NIP.VEIAG..V..EAN.M.AVLGALTTPGT.D.V.PVAVLDLGGGSTDAAFMNRKKEV..VS..I.HM.A.G..A..G....E....M....VN....MIIA..A......E..L....G......LS.D.....RQLAEDIK.R.YPVAKVESLFSIRMEDGTVRFFE.KPLDPQTFARVCLL.KE.GSLVPL..PPDLQLEKVRQVRRKAKQKVFVSNAVRALSKV..APSGNLRLI.DFVIMVGGSALDFEIPEMISEALAGYGIVAGRGEIRGSEGPRNAVATGLVLS-g.................................................................................................
#=GC seq_cons                        .....................................................................................................................................V-VspGA-tIMcslppstslpDlpGEsGTNlGGMLE+VRpsMupLTsp......s.s-IpIQDLLAVDThlP.c.........VpGGLAGEFShEsAVGlAAMVKoc+Lp...MphIAcclppcL......slp.VclGG..V..EA-.M.AIhGALTTPGT.s.p.PLAILDhGAGSTDAulIspcGpl..pu..l.HL.A.G..A..G....-....M....VT....MLIs..o......E..L....G......Ls.D.....htLAE-IK.K.YPLAKVESLFHlRHEDGoVpFF-.pPLsPplFARVVll.Ks.sthlPl..sschulEKIRtVRRpAKc+VFVTNAlRALcpV..uPTGNlRcI.sFVVLVGGSALDFEIPphlTDALucYslVAGRGNIRGsEGPRNAVATGLlLu...................................................................................................
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