GenomeNet

Database: Pfam
Entry: DDR
LinkDB: DDR
Original site: DDR 
#=GF ID   DDR
#=GF AC   PF08841.9
#=GF DE   Diol dehydratase reactivase ATPase-like domain
#=GF AU   Mistry J
#=GF SE   pdb_2d0o
#=GF GA   24.60 24.60;
#=GF TC   24.60 24.60;
#=GF NC   24.50 24.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9990728
#=GF RT   Biochemistry of coenzyme B12-dependent glycerol and diol
#=GF RT   dehydratases and organization of the encoding genes. 
#=GF RA   Daniel R, Bobik TA, Gottschalk G; 
#=GF RL   FEMS Microbiol Rev. 1998;22:553-566.
#=GF RN   [2]
#=GF RM   16338403
#=GF RT   Release of a damaged cofactor from a coenzyme B12-dependent
#=GF RT   enzyme: X-ray structures of diol dehydratase-reactivating
#=GF RT   factor. 
#=GF RA   Shibata N, Mori K, Hieda N, Higuchi Y, Yamanishi M, Toraya T; 
#=GF RL   Structure. 2005;13:1745-1754.
#=GF DR   INTERPRO; IPR030994;
#=GF CC   Diol dehydratase (DDH, EC:4.2.1.28) and its isofunctional
#=GF CC   homologue glycerol dehydratase (GDH, EC.4.2.1.30) are enzymes
#=GF CC   which catalyse the conversion of glycerol 1,2-propanediol, and
#=GF CC   1,2-ethanediol to aldehydes [1].  These reactions require
#=GF CC   coenzyme B12.  Cleavage of the Co-C bond of coenzyme B12 by
#=GF CC   substrates or coenzyme analogues results in inactivation during
#=GF CC   which coenzyme B12 remains tightly bound to the apoenzyme.  This
#=GF CC   family comprises of the large subunit of the diol dehydratase
#=GF CC   and glycerol dehydratase reactivating factors whose function is
#=GF CC   to reactivate the holoenzyme by exchange of a damaged cofactor
#=GF CC   for intact coenzyme.
#=GF SQ   147
#=GS G7V6B4_THELD/278-606      AC G7V6B4.1
#=GS X5KLQ4_9MYCO/276-609      AC X5KLQ4.1
#=GS A0A0K8JAP0_9FIRM/275-602  AC A0A0K8JAP0.1
#=GS V5XIJ9_MYCNE/256-514      AC V5XIJ9.1
#=GS K6DUM9_BACAZ/274-601      AC K6DUM9.1
#=GS A0A0G3Q651_KLUIN/275-602  AC A0A0G3Q651.1
#=GS C0E8B5_9FIRM/284-613      AC C0E8B5.1
#=GS I4EQU8_9ACTN/277-610      AC I4EQU8.1
#=GS A0A075KEJ4_9FIRM/275-602  AC A0A075KEJ4.1
#=GS R5TMH6_9FIRM/272-599      AC R5TMH6.1
#=GS S6F9H4_9CLOT/246-573      AC S6F9H4.1
#=GS X5KWD4_9MYCO/1-212        AC X5KWD4.1
#=GS A0A099SEN2_9CLOT/279-606  AC A0A099SEN2.1
#=GS A0A0J1J1Z3_9FIRM/273-600  AC A0A0J1J1Z3.1
#=GS I6XQD8_PROPF/275-602      AC I6XQD8.1
#=GS A6TE97_KLEP7/277-604      AC A6TE97.1
#=GS I2BBY5_SHIBC/277-604      AC I2BBY5.1
#=GS A0A0T9Y9F5_SALET/1-122    AC A0A0T9Y9F5.1
#=GS A0A0A1G215_9MYCO/267-570  AC A0A0A1G215.2
#=GS J2X5M4_KLEPN/275-602      AC J2X5M4.1
#=GS R9IZJ5_9FIRM/274-601      AC R9IZJ5.1
#=GS S0RQE9_ENTAV/276-603      AC S0RQE9.1
#=GS A0A132PKQ1_9MYCO/263-564  AC A0A132PKQ1.1
#=GS F7NH21_9FIRM/274-601      AC F7NH21.1
#=GS A0A132PU77_9MYCO/276-609  AC A0A132PU77.1
#=GS D8JB91_HALJB/277-605      AC D8JB91.1
#=GS A0A0F4LUE7_9LACO/278-605  AC A0A0F4LUE7.1
#=GS A0A0T7RRA3_SALET/275-396  AC A0A0T7RRA3.1
#=GS A0A0M2U968_9FIRM/274-601  AC A0A0M2U968.1
#=GS A0A162S1V9_9CLOT/272-599  AC A0A162S1V9.1
#=GS A0A0F2Q594_9CLOT/275-603  AC A0A0F2Q594.1
#=GS D1AFL7_SEBTE/275-602      AC D1AFL7.1
#=GS W1FQ41_ECOLX/232-488      AC W1FQ41.1
#=GS A0A0C1LF12_9PSEU/285-630  AC A0A0C1LF12.1
#=GS A0A0R1RN13_9LACO/276-604  AC A0A0R1RN13.1
#=GS A0A098Y1Y5_9ACTN/273-606  AC A0A098Y1Y5.1
#=GS U7VEM7_9FUSO/277-602      AC U7VEM7.1
#=GS A0A161ZII4_9EURY/276-604  AC A0A161ZII4.1
#=GS A0A0R1XEN2_9LACO/279-606  AC A0A0R1XEN2.1
#=GS E4RMA0_HALHG/276-603      AC E4RMA0.1
#=GS J2DGG7_KLEPN/277-604      AC J2DGG7.1
#=GS A0A0F3RTY4_9LACO/276-603  AC A0A0F3RTY4.1
#=GS T0C8S1_ALIAG/276-603      AC T0C8S1.1
#=GS A0A117L7W0_9FIRM/273-602  AC A0A117L7W0.1
#=GS A0A0L6U0P1_9FIRM/274-601  AC A0A0L6U0P1.1
#=GS Q03Q33_LACBA/276-603      AC Q03Q33.1
#=GS F9ELP3_FUSNU/274-601      AC F9ELP3.1
#=GS B8FDN6_DESAA/272-599      AC B8FDN6.1
#=GS R5XK30_9FIRM/273-600      AC R5XK30.1
#=GS A0A0P0SF11_9PSEU/274-601  AC A0A0P0SF11.1
#=GS C6PYA4_9CLOT/272-599      AC C6PYA4.1
#=GS G2G2A6_9FIRM/275-602      AC G2G2A6.1
#=GS W1E9D1_KLEPN/275-602      AC W1E9D1.1
#=GS A0A0Q5VG80_9ACTN/279-607  AC A0A0Q5VG80.1
#=GS H6LEQ0_ACEWD/273-600      AC H6LEQ0.1
#=GS E6MIY1_9FIRM/273-600      AC E6MIY1.1
#=GS W1G4Q8_ECOLX/273-600      AC W1G4Q8.1
#=GS A1UN21_MYCSK/264-567      AC A1UN21.1
#=GS A0A101EFQ8_9BACT/278-606  AC A0A101EFQ8.1
#=GS A0A0M2K4E0_9MYCO/260-563  AC A0A0M2K4E0.1
#=GS W1E5Z1_KLEPN/1-162        AC W1E5Z1.1
#=GS A0A095XCV6_9FIRM/275-601  AC A0A095XCV6.1
#=GS H1LI38_9LACO/276-603      AC H1LI38.1
#=GS F9DQU4_9BACL/277-604      AC F9DQU4.1
#=GS W1FRT9_ECOLX/1-80         AC W1FRT9.1
#=GS A0A0R2EGJ7_9LACO/277-604  AC A0A0R2EGJ7.1
#=GS A0A100W353_9MYCO/259-562  AC A0A100W353.1
#=GS D9S1P8_THEOJ/273-600      AC D9S1P8.1
#=GS A0A100VWP8_9MYCO/280-518  AC A0A100VWP8.1
#=GS E3GH67_EUBLK/273-600      AC E3GH67.1
#=GS A0A162SCA6_9CLOT/279-606  AC A0A162SCA6.1
#=GS D2S4X8_GEOOG/285-618      AC D2S4X8.1
#=GS A0A0H4QNK4_9LACO/276-603  AC A0A0H4QNK4.1
#=GS J3ES93_9LACO/277-604      AC J3ES93.1
#=GS K0UJZ1_MYCVA/261-564      AC K0UJZ1.1
#=GS A0A0R1RGZ5_9LACO/277-604  AC A0A0R1RGZ5.1
#=GS C6PQK2_9CLOT/272-599      AC C6PQK2.1
#=GS D7GD20_PROFC/273-600      AC D7GD20.1
#=GS W1HST3_KLEPN/1-162        AC W1HST3.1
#=GS S3X9M6_9ACTN/274-602      AC S3X9M6.1
#=GS A3CLC8_STRSV/275-604      AC A3CLC8.1
#=GS A0A0S2W4Y0_9FIRM/274-601  AC A0A0S2W4Y0.1
#=GS A0A0F5HML0_9BACI/274-601  AC A0A0F5HML0.1
#=GS A1TGM6_MYCVP/268-571      AC A1TGM6.1
#=GS B2TLK5_CLOBB/278-605      AC B2TLK5.1
#=GS Q8Y7W3_LISMO/275-602      AC Q8Y7W3.1
#=GS A0A0R2LNX2_9LACO/276-603  AC A0A0R2LNX2.1
#=GS A0A071LPX2_9ENTR/275-602  AC A0A071LPX2.1
#=GS A0A172USQ4_9MYCO/275-608  AC A0A172USQ4.1
#=GS A0A0R2L312_9LACO/277-604  AC A0A0R2L312.1
#=GS A0A0R1HLP2_9LACO/279-606  AC A0A0R1HLP2.1
#=GS C4S897_YERMO/275-602      AC C4S897.1
#=GS K0UFG3_MYCVA/5-244        AC K0UFG3.1
#=GS A0A010YIW5_9ACTN/296-551  AC A0A010YIW5.1
#=GS A0A089PLR2_PLUGE/277-604  AC A0A089PLR2.1
#=GS I9LEU7_9FIRM/275-602      AC I9LEU7.1
#=GS A0A0R2B4T5_LACCL/278-605  AC A0A0R2B4T5.1
#=GS C6JP61_FUSVA/274-601      AC C6JP61.1
#=GS W9ATZ9_9MYCO/274-579      AC W9ATZ9.1
#=GS A0A017T542_9DELT/6-49     AC A0A017T542.1
#=GS A6TDD5_KLEP7/275-602      AC A6TDD5.1
#=GS U2QEV7_9ACTN/273-600      AC U2QEV7.1
#=GS S0J4Q5_9FIRM/274-601      AC S0J4Q5.1
#=GS W9BLL4_9MYCO/272-605      AC W9BLL4.1
#=GS A0A0T1WE25_9MYCO/260-563  AC A0A0T1WE25.1
#=GS I4BU32_ANAMD/277-605      AC I4BU32.1
#=GS A5VMA9_LACRD/278-605      AC A5VMA9.1
#=GS A0R5U9_MYCS2/262-565      AC A0R5U9.1
#=GS A0A0T1W7J9_9MYCO/279-612  AC A0A0T1W7J9.1
#=GS R5BN42_9FIRM/275-602      AC R5BN42.1
#=GS A0A132T3J4_9MYCO/277-593  AC A0A132T3J4.1
#=GS D2Z8G8_9BACT/278-606      AC D2Z8G8.1
#=GS A0A172UJQ0_9MYCO/269-514  AC A0A172UJQ0.1
#=GS E3CVA2_9BACT/277-605      AC E3CVA2.1
#=GS A9MLQ0_SALAR/275-602      AC A9MLQ0.1
#=GS Q8XLV8_CLOPE/280-607      AC Q8XLV8.1
#=GS G9YVN8_9FIRM/274-601      AC G9YVN8.1
#=GS V5X9M2_MYCNE/272-605      AC V5X9M2.1
#=GS R6G9W5_9FIRM/273-601      AC R6G9W5.1
#=GS A0A0H3J8Q7_CLOPA/275-602  AC A0A0H3J8Q7.1
#=GS R5RU48_9FIRM/273-600      AC R5RU48.1
#=GS A0A0T9XBB3_SALET/1-162    AC A0A0T9XBB3.1
#=GS E3H9G3_ILYPC/274-601      AC E3H9G3.1
#=GS I3VRW4_THESW/275-603      AC I3VRW4.1
#=GS F0Z327_9CLOT/273-600      AC F0Z327.1
#=GS A0A0R1S1M4_9LACO/276-603  AC A0A0R1S1M4.1
#=GS A0A0T7RPS8_SALET/3-38     AC A0A0T7RPS8.1
#=GS A0A0R2D0U7_9LACO/277-604  AC A0A0R2D0U7.1
#=GS A0A0X8D3V8_9BACL/223-338  AC A0A0X8D3V8.1
#=GS G8PEJ6_PEDCP/276-603      AC G8PEJ6.1
#=GS A0A0D1VHX9_ANEMI/276-603  AC A0A0D1VHX9.1
#=GS C4LFD2_TOLAT/275-602      AC C4LFD2.1
#=GS S2WWZ2_9ACTN/274-601      AC S2WWZ2.1
#=GS O31043_SALTY/275-602      AC O31043.2
#=GS A8AEN2_CITK8/275-602      AC A8AEN2.1
#=GS X5KSI9_9MYCO/259-562      AC X5KSI9.1
#=GS A0A076N3Z9_AMYME/275-601  AC A0A076N3Z9.1
#=GS R6EEW3_9FIRM/1-159        AC R6EEW3.1
#=GS D2TPR1_CITRI/275-602      AC D2TPR1.1
#=GS A0A0V8JEA9_9BACI/276-603  AC A0A0V8JEA9.1
#=GS R9KL89_9FIRM/274-601      AC R9KL89.1
#=GS E3HDB0_ILYPC/274-601      AC E3HDB0.1
#=GS R6G8Y1_9FIRM/273-601      AC R6G8Y1.1
#=GS A0A0A7FXY5_9CLOT/279-606  AC A0A0A7FXY5.1
#=GS A0A099S494_9CLOT/272-599  AC A0A099S494.1
#=GS D5XBU6_THEPJ/275-603      AC D5XBU6.1
#=GS W1DMB2_KLEPN/1-162        AC W1DMB2.1
G7V6B4_THELD/278-606                 ............................................................................................................................................VNVESGAEAIMKVLEESQPVKNIFGQPGTNVGGMMERVRRTMSNLT.GL..................PVADIHIKDLLAVDTLVPQR.........VVGGIAGEFSQEHGVALAVMVETEKLP...MTQ.LAE..AISQ.ET......GVK.VMI..GG..V..EAEM.A.VRG..ALTTP.......GT.K.K.PLAILDLGAGSTDASLMK..ENGEI..D..L..I.H.L.A.G...A..G....N....M....VN....TII......A..S......E..L....G......IE.S.....MELAESIK.R.YPLCKVESPFHVRQEDGRVRFFD.NPLSPNLFGKNALV.VEdDILMPL..ELDIPVERIREIRRRAKREVFVTNSLRALERV..SPAGNVRLL.DYVVLVGGSALDFEIPSMITDALSRFG..VVAGRGNIRGTEGPRNAVATGLVL--gf................................................................................................
X5KLQ4_9MYCO/276-609                 ............................................................................................................................................VDVSGGAAEIMAAVERVGPLLDVAGEPGTNTGGMIANVRQSMADLS.GH..................ATADVRIQDLLAVDTFVPQE.........VRGGVAGEVALENAVALAAMVRTKDSV...MQA.VAD..AVAD.RLradgapGVR.VIV..GG..V..EAEM.A.VRG..ALTTP.......GT.D.K.PLVVLDLGGGSTDAALIE..ADGTI..A..A..V.H.L.A.G...A..G....D....L....VT....KLI......D..A......E..L....G......LD.N.....LELAEDVK.R.FPLGKAESFFHVRLENGTVQFFE.TPLPTTAFARVVTL.AE.HGMNPI..PTRHTMDRIRMVRRGAKERVFVVNALRALKAI..APAGDLRQI.GFVVLLGGCALDFEIPELIADALASYG..IVCGTGNVRGTEGPRNAVASGLVAA-h.................................................................................................
A0A0K8JAP0_9FIRM/275-602             ............................................................................................................................................VDVEAGATKIMEAVERVQPVVDVQGEAGTNVNGMLERVRQVMGELT.GQ..................PLSEMKIQDILAVDTFVPQK.........VQGGLAGEFALETAVALAAMVKTSRLP...MQQ.IAD..VLTE.RL......HVR.VVI..AG..V..EANM.A.ILG..ALTTP.......GT.A.K.PLAILDMGGGSTDAATVT..GDNQV..F..S..I.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LN.D.....FDLAEEIK.K.YPLAKVESLYHIRLEDGTVKFFE.QHLDPEVFARVVIL.RG.QDMIPI..PTKHSLDKIRHVRREAKKRVFVTNALRSLVRV..APTGNIRHM.EFVVLVGGSALDFEVADMVSDALAEYG..IVCGRGNIRGTEGPRNAVATGLVLS-h.................................................................................................
V5XIJ9_MYCNE/256-514                 ..........................................................................................................................dglvhivqladiaaaanv----------------------------------------------.--..................--------------------.........----------RRGAVAVDSLVMATMGGddvSPA.DAD..ALAA.AL......GVP.VTR..ID..S..EAAA.A.RAG..ALTTP.......GL.P.A.DVVVVDVGGGTVD--VVA..AGDRV..V..L..-.-.-.P.G...A..G....Q....L....LT....AAT......A..A......A..L....D......I-.S.....TSAAEYAK.R.AEAVTAVTVQLVEDEHGRRRFLD.TPIDGRSTGWLLTA.AP.SGLLPF..TAAMAAAEWRSWRLAAKRLVIGGNVTRGVQDV..GADA-----.TAVLLVGGGAGDDELVRALAERLGH-D..VSVGRGNVAGELGHRFAVAYGLVV--la................................................................................................
K6DUM9_BACAZ/274-601                 ............................................................................................................................................VDVDEGAEKMMHAMTNAAPIEDIKGEAGTNAGGMLERVRQVMSELT.KQ..................QPDDIKIQDLLAVNTFIPQK.........VKGGLAEEFSMENAVGIAAMVKADKLQ...MQM.IAD..ELRS.RI......NVK.VEV..GG..V..EADM.A.IRG..ALSTP.......GT.N.V.PIAIVDMGAGSTDASIIT..KSGKT..T..S..V.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LD.D.....IALAEDIK.K.YPLAKVESLFHIRHEDGTVQFFE.RPLEPHVFARVVIL.KE.GTMIPI..PGQHSVEKVKIVRRGSKEKVFVTNALRALTMV..APTGNIREM.EFVVLVGGSALDFEIPQLVTDALSQYS..IVAGRGNIRGTEGPRNAVATGLILA-l.................................................................................................
A0A0G3Q651_KLUIN/275-602             ............................................................................................................................................VDVAAGADAIMKAVNECPTLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSSDVFIQDLLAVDTAVPVN.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAH..EIEQ.KL......HVD.VQV..GG..A..EAEA.A.IFG..ALTTP.......GT.S.R.PLAILDLGAGSTDASIIT..PQGQI..T..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPAVFARVCVV.KP.DELVPL..PGDLALEKVRIIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYR..LVAGRGNIRGVEGPRNAVATGLILSW..................................................................................................
C0E8B5_9FIRM/284-613                 ............................................................................................................................................IEVNSGADHIMKELASCHEILDIAGEQGTNVGALINRIKQSMSELT.GE..................SVDEMKIIDMLAADTFASVE.........VAGGLAGEAAMENVVMLAAMVQTSKLP...MQA.IAD..ELSK.LT......GIY.VRV..EG..R..EAEM.A.LKG..ALTTP.......GA.D.I.PLAILDLGGGSTDAALID..GDGRV..T..A..I.H.H.A.G...A..G....E....M....VT....KII......D..L......E..L....D......LN.D.....RDTAELIK.K.YPLAKVEGLLYLRFEDGSVKFAS.EPLPPQLFSRVVIV.TE.DQLVPIrsSKRLTIDRIALVRREAKKKVFNVNAKRALTEV..APGGDIRKI.GSVALVGGSSQDFEIADLLAEYLSSYR..ITAGRANLLGMLEPHSAVALGLAL--ad................................................................................................
I4EQU8_9ACTN/277-610                 ............................................................................................................................................VDVDAGAEAIMDAVGRAQPLDDARGEPGTHVGGMLAQVRDTMADVM.DSpgl............pavPVAEIAIRDVLAVDTFVPAE.........VRGGLAGEVALENAVALAAMVSTSRSR...MQV.VAD..QVSE.GL......GAA.AAI..GG..V..EGEM.A.VSG..ALTTP.......GV.D.R.PVAVLDLGGGSTDAALLT..RDGRA..T..A..V.H.V.A.G...A..G....E....L....VT....KLV......H..S......E..L....A......LG.D.....REVAESVK.R.CPLAQVESFFHVRHEDGTVQFFE.TPLPPEVYARVVVL.TP.EGPAPV..GTRHRLDHVRRVRREAKRRVFVVNALRALRQV..APGGNLREL.DFVVLLGGSALDFEIPDMIADALAPHG..VVCGTGNVLGTEGPRNAVATGLVRA-w.................................................................................................
A0A075KEJ4_9FIRM/275-602             ............................................................................................................................................IDVESGANKIMETVERVQPVLDVQGEAGTHVNGMLERVRQVMSELT.EQ..................PLADMKIQDILAVDTFVPQK.........VQGGLAGEFALENAVALAAMVKTSRLP...MQQ.IAN..KLTQ.EL......GVK.VVI..AG..V..EANM.A.IRG..ALTTP.......GT.D.K.PLAILDMGGGSTDAAIIT..RDERV..M..S..I.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LN.D.....FDLSEDIK.K.YPLAKVESLYHIRLEDGTVRFYE.QHLKPEVFSRVVIL.KD.GDMVPI..PSSHPLDKIRHVRREAKKRVFVTNALRSLARV..APTGNIRHI.EFVVLVGGSAMDFEVGDMVTDALAEYS..IVCGRGNIRGSEGPRNAVATGLVLSY..................................................................................................
R5TMH6_9FIRM/272-599                 ............................................................................................................................................VDLDEGAEKIMQVVSDAGTIYDMEGEHDTNVGNMFSRIKQGMENLD.ET..................AKREIHITDILAVDTMAPVR.........ISGALAGETCLEKAVGIAAMVKTRHLP...MQK.IAE..QLRI.EL......GVN.VMV..AG..V..EAVM.A.SLG..ALTTP.......GT.S.L.PLAILDMGGGSTDAAVIS..EDGKV..S..M..T.H.Q.A.G...A..G....E....L....VS....MLI......E..T......E..L....G......LG.D.....RHMAEQIK.K.YPLAKVESLFHMRMENGQMTFVE.QSIDPRFYGRVVLL.TE.DGMIRL..EQDIPMEKIVQVRREAKRKVFVTNAFRALKKV..APGQDLKHI.SNVVLVGGSAEDFEIPEMLMEELSEFR..IVCGRGNIRGEEGPRNAVATGLVLSY..................................................................................................
S6F9H4_9CLOT/246-573                 ............................................................................................................................................VDINTGAEYIMRKVNKIGEIKDVDGEKGTNIAFMINDIKNHMSEIS.EI..................DTSKVKIKDILAVDTTIPLK.........IKGGIANETYKEKAVAIAIMVKTHKLP...LNS.IKS..ILES.EL......ETP.VEI..NG..I..EGVM.A.TIG..ALTTP.......GT.K.L.PIAIVDIGGGSTDVAILE..KTGEV..K..S..I.H.L.A.G...A..G....E....L....VT....MII......N..L......E..L....G......LN.D.....VSLAEEIK.R.NIIGKVESLYTLRTEAGEVKFFD.KPLNPKLYGRIVVI.KN.DKLLPI..YKNITIEEVVKVRRRAKESVFIKNIIRGLKTI..SPMGNLHFI.PNVVLVGGSALDFEIPNMVVQELSNYG..IVSGCGNIRNSEGPRHAVSTGLVLHY..................................................................................................
X5KWD4_9MYCO/1-212                   ..........................................................................................................................................mr----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......--P.VFV..GG..A..EARA.G.WIG..ARSTP.......GL.P.R.EVVVIDIGAGTLD--VIT..GDDSV..A..V..-.-.-.A.G...A..G....D....L....IT....AGV......A..L......S..L....S......I-.S.....TTLAENAK.M.HPAVRVETPHLIAREDGVREFPE.DPVPGSSVGRLSLV.TAhGDLVPL..GSRLAPETWHRERLGIKATVLERGLLRARRVL..-RGG-FADD.ALLLLAGGGAEDAELVTA-AARFAHLG..QVA-IADVAGRFGPRCAVAWGLVL--ga................................................................................................
A0A099SEN2_9CLOT/279-606             ............................................................................................................................................VDVEEGAEKIMEAVKLCVPVQDIKGECGTNAGGMLERVRQVMAKLT.KQ..................KIVDIKIQDLLAVDTFIPQK.........VKGGLAEEFSMENAVGIAAMVKADKLQ...MQM.IAD..KLQE.KL......NVT.VEV..GG..V..EADM.A.IRG..ALTTP.......GS.S.K.PLAILDMGAGSTDASIIN..KQDQI..C..S..I.H.L.A.G...A..G....N....M....VT....MLI......K..S......E..L....G......LE.D.....FNLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.NPLDPSVFAKVVIL.KE.GMLIPI..DGQTSLEKIKIIRRSAKEKVFVTNCLRALSIV..SPTGNIRDI.EFVVLVGGSSLDFEVPQLVTDALSQYG..VVAGRGNIRGTEGPRNAVATGLILA-f.................................................................................................
A0A0J1J1Z3_9FIRM/273-600             ............................................................................................................................................VNIDAGADAIMDTLSGAGEIRDISGQQETNVGNMLSGIKKGMEKVT.DE..................TGQDIRITDILAVDTLAPVQ.........ISGSLAGEMCMEKAVGIAAMVKTRQLP...MEK.IAD..ELKK.EL......GIY.TKV..AG..V..EAVM.A.TLG..ACTTP.......GT.Q.L.PLAILDLGGGSTDAAMID..EKGMV..R..T..T.H.Q.A.G...A..G....E....L....VS....MLI......Q..T......E..L....G......LS.A.....RTTAEQIK.R.YPLARVESLFHMRLENGAMQFFD.ESIDPRYFGNVVLL.HP.EELIKI..EEDIPMEKIASVRREAKKKVFVRNAVRALTQV..APDHNLRNI.PNVVLVGGSAEDFEIPQMLMEELSNYK..IVCGRGNIRRCEGPRNAVATGLVLSY..................................................................................................
I6XQD8_PROPF/275-602                 ............................................................................................................................................VDVDLGAAEIMDVASRIRNLSDITGEAGTNVGGMMEKVRVTMAQLT.NQ..................HTRDIRITDLLAVDTRVPQQ.........VAGGIANEFSMEAAVGIAVMVRTDRLQ...MER.IAS..ELAA.EI......GVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.A.A.PIAILDMGAGSTDASVMR..PDGTG..T..S..I.H.L.A.G...A..G....N....M....VT....LMI......Q..S......E..L....G......LD.S.....FDLAEDIK.R.HPLAKVESVFNIRHEDGTVQFFE.DPLPGHVYARTVVL.KP.DGMVPL..DVDLPVETIRQVRIRAKEQVFVTNAIRALQRV..SPTSEVRGI.DFVVLVGGSALDFEIPQLVTRALADYR..VVAGRANIRGVEGPRNAVATGLVL--gg................................................................................................
A6TE97_KLEP7/277-604                 ...........................................................................................................................................a-DVAEGAEAIMQAMSACAPVRDIRGEPGTHAGGMLERVRKVMASLT.GH..................EMSAIYIQDLLAVDTFIPRK.........VQGGMAGECAMENAVGMAAMVKADRLQ...MQV.IAR..ELSA.RL......QTE.VVV..GG..V..EANM.A.IAG..ALTTP.......GC.A.A.PLAILDLGAGSTDAAIVN..AEGQI..T..A..V.H.L.A.G...A..G....N....M....VS....LLI......K..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYG..VVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
I2BBY5_SHIBC/277-604                 ...........................................................................................................................................a-DVACGAGAIMQAVAECAPVSDIRGEPGTHAGGMLERVRQVMASLS.GH..................GAHEVFIQDLLAVDTFIPRK.........VQGGLAGEFSMENAVGIAAMVKSDRLQ...MEV.IAG..ELSQ.RL......ATR.VEV..GG..V..EANM.A.ISG..ALTTP.......GS.D.T.PLAILDLGAGSTDAATIN..RAGQV..K..S..V.H.L.A.G...A..G....N....M....VS....LLI......K..T......E..L....G......LS.E.....LQLAEEIK.K.YPLAKVESLFSIRHENGAVEFFR.EPLSPAVFAKVVYI.KE.GTLVPI..DNQTSLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGEIRDI.AFVVLVGGSALDFEIPQLITDALSHYG..VVAGQGNIRGTEGPRNAVATGLVL--gm................................................................................................
A0A0T9Y9F5_SALET/1-122               ............................................................................................................................................-----------------------------------------MASLT.SH..................DMNAVHIQDLLAVDTFIPRA.........VQGGIAGECSMENAVGIAAMVKSDRLQ...MQA.IAS..ELSA.RL......NTP.VEV..GG..V..EANM.A.VAG..ALTTH.......GC.A.V.PLAILDLGAGSTDAAIIN..NDGAV..R..R..C.R.R.A.G...-..-....-....-....--....---......-..-......-..-....-......--.-.....--------.-.-----------------------.--------------.--.------..--------------------------------..---------.---------------------------..--------------------------..................................................................................................
A0A0A1G215_9MYCO/267-570             ............................................................................................................................................VEFRIDGVPVRYSPAQAHAI--LRREPPGSVVRI--RLRSIPTADG.EI..................AVDDAFFTDLAALDSGTWLRrgvaeargtVVALLAADHVEDAATTLAELT------...---.---..----.--......GRP.ART..IA..T..EPEA.A.ARG..ARTTP.......GL.P.P.ESVVCDIGGGTID--LIG..SERTV..T..A..-.-.-.A.G...A..G....E....S....IT....VAV......A..R......M..L....N......I-.P.....RALAERVK.R.TPAIRVEGPHVAHEEDGRRLFLD.APAPADAIGRLCTR.GT.AGLVPF..STKLAAEEWRSLRLAIKQETVAANIARCLAAF..EKPP-----.PALVLAGGGALDDELLRTVGESLRSVG..VVVGRANIDGVHGPRFAVASGLVH--ls................................................................................................
J2X5M4_KLEPN/275-602                 ............................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVAGEAGTNIGGMLEHVRQTMAELT.NK..................PAQEIRIQDLLAVDTAVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAL.IAR..EIEH.KL......QIA.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..AQGEI..S..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.SALPPTVFARVCVV.KP.DELVPL..PGDLPLEKVRAIRRSAKSRVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYR..LVAGRGNIRGCEGPRNAVASGLLLSW..................................................................................................
R9IZJ5_9FIRM/274-601                 ............................................................................................................................................VDVDAGGEKIMQAVESLPVLEDVRGEPGTNAGGMLEKVRQVMANLT.KQ..................HPKDIHIQDLLAVDTFTPQK.........VQGGLANEFSQENAVGIAAMVKADRLQ...MEA.IAK..EFSE.QI......NIP.VQV..GG..V..EADM.A.IRG..ALTTP.......GT.N.K.PLAILDMGAGSTDASIIN..KEGEI..H..S..I.H.L.A.G...A..G....N....M....VT....LLI......Q..S......E..M....G......LD.S.....FDIAEDVK.K.YPLAKVESFFHIRHENGTVEFFS.EPLDPNIFAKTVIL.KE.GNMIPL..EGDWSMEKIRLIRRQAKQKVFVTNALRALARV..SPTGNVRDI.QFVVLVGGSALDFEVPQMVTDALSQYK..VVAGRGNIRGTEGPRNAVATGLVLS-l.................................................................................................
S0RQE9_ENTAV/276-603                 ............................................................................................................................................VGISAGAEKIMETVSAFEVIDNVTGEPGTNVGGMLEKVRLTMAELT.DR..................PVNQIFIQDLLAVDTFVPIS.........VKGGLAGEFSMEQAVGIASMVKSDHLQ...MSK.IAD..AIQQ.DL......GIK.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.S.A.PLAILDLGAGSTDASIIK..KDERI..V..A..T.H.L.A.G...A..G....D....M....VT....MLI......Q..S......E..L....G......LE.D.....VYLAEDIK.K.YPLAKVENIFYIRHEDGSVQFFD.QPLDPSLFAKVVVV.TP.DGYVPI..PGDDSIEKIRLVRQTAKERVFVTNALRALRRV..SPTGSIRDI.PFVVIVGGSALDFEVPQIVTNALSHYG..LVAGRGNIRQIEGPRNAVATGLILSY..................................................................................................
A0A132PKQ1_9MYCO/263-564             ............................................................................................................................................VEFRVDGKGVRYSPAQAHSI--LRREPPGNVVRI--RLRSLPH--H.EM..................AVDDAFFTDLSALDNGAWLRrgvadargtVVALLAADHVEDAAATLGELT------...---.---..----.--......DRP.ART..IA..T..EPEA.A.AWG..ARTTP.......GL.P.P.DSVVCDIGGGTID--LVG..DDRIV..T..A..-.-.-.A.G...A..G....E....T....IT....VAV......A..R......M..L....N......I-.P.....RALAERVK.R.TPAIRVEGPHVAHEEDGRRLFLD.SPAPAEAIGRLCTR.GT.VGLVPF..SNKLAAEEWRSLRLAIKQETVAANIARCMKAFekPPTA-----.--LVLAGGGALDDELLRTVGESLRAVP..IVVGRANIDGIHGPRFAVASGLVH--ls................................................................................................
F7NH21_9FIRM/274-601                 ............................................................................................................................................IDVEAGAAKIMAAVEQVQPVQDVQGEAGTNVNGMLERVRQVMSELT.GQ..................PLDAMKIQDILAVDTFVPQK.........VQGGLAGEFALENAVALAAMVKTSRLP...MQQ.IAD..QLRR.QL......GVR.VVI..AG..V..EANM.A.IRG..ALTTP.......GT.D.K.PLAILDMGGGSTDAAIIS..RDERT..S..A..I.H.L.A.G...A..G....D....M....VT....MLI......H..S......E..L....G......LN.D.....LALAEEIK.M.YPLAKVESLYHIRLEDGTVQFFE.QHLPPQVFSRVVIL.KE.SEMIPI..PTDHPLDKIRHVRREAKRRVFVTNALRALTRV..APTGNIRHI.SFVVLVGGSALDFEVADMVTDALAEYG..IVCGRGNIRGTEGPRNAVATGLVLSY..................................................................................................
A0A132PU77_9MYCO/276-609             ............................................................................................................................................VDVSRGAVEIMAAVERVSPLADVTGEAGTNTGGMIANVRQSMADLS.NH..................AVADVHIQDLLAVDTFVPQE.........VRGGVAGEVALENAVALAAMVRTRESG...MRA.VAD..AVRQ.RLhaagacDVE.VVV..GG..V..EAEM.A.VLG..ALTTP.......GT.D.K.PLVVLDLGGGSTDAALIE..AAGDI..D..A..V.H.L.A.G...A..G....D....L....VT....KLI......D..A......E..L....G......LD.N.....LELAEDIK.R.YPLGKAESFFHVRLENGTVQFFE.KPLPATAFARVVTL.AE.HSMSPI..PTRHSIDRIRVVRRAAKERVFVVNALRALRTI..APGGDLRQI.GFVVLLGGCALDFEIPELIADALAPYG..IVCGTGNVRGSEGPRNAVATGLVAS-h.................................................................................................
D8JB91_HALJB/277-605                 ............................................................................................................................................IGIDQGADEIMAQVEDLWPIDDIRGERGSNIGGMLSRAREQMGEIT.GQ..................EFSEINIRDIMAVDTLVPQA.........VEGSVASEHSMETAVGLAAMVKTSELP...MQQ.IAD..EVED.RL......ETT.VHI..QG..I..EANM.A.ILG..SLTTP.......GT.D.V.PFAILDMGGGSTDAAYID..ADNDI..T..S..I.H.L.A.G...A..G....D....M....VT....MLI......A..S......E..L....G......LD.D.....WELAEGLK.K.YPVAKVETLFSIRHEDGTVTFLD.EAVDSETFGRIVLL.TDdGDMEPV..SIDESVEKVRRTRRRAKERVFVANAKRALRQI..SPTKSVRYH.SFVVMVGRSALDFEIPELISDALAEYG..IVCGRGNIRSTTGPRNAVATGLCLSY..................................................................................................
A0A0F4LUE7_9LACO/278-605             ............................................................................................................................................INVTAGADAIMDKVSQFQQIQDIVGESGTNVGGMLEAVRQTMADLT.GK..................TNSDIQIQDLLAVDTQVPVK.........VRGGLAGEFSNESAVGIAAMVKSDHLQ...MQV.IAD..LIES.EL......HTK.VEI..GG..A..EAEA.A.IRG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIID..KDNNI..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....RNLAEDIK.K.YPLAKVDNLFQLRHEDGSVQFFE.DPLPAELFARVVVI.EP.DGYQPL..PGKLNIERVRFVRRTAKRRVFVTNAQRALAHV..SPTGNVRDI.PFVVIVGGSALDFEIPQLVTDQLAQYN..LVSGRGNIRATEGPRNAVATGLILG-y.................................................................................................
A0A0T7RRA3_SALET/275-396             ............................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSSEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAR..EIEQ.KL......NID.VQI..GG..A..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....-....--....---......-..-......-..-....-......--.-.....--------.-.-----------------------.--------------.--.------..--------------------------------..---------.---------------------------..--------------------------xxxxxx............................................................................................
A0A0M2U968_9FIRM/274-601             ............................................................................................................................................VDLEEGADAIMEAMEKVKPLQDASGTPGTNVGGMLERVRQVMSDLT.KQ..................DRDQIRIQDILAVNTFVPQK.........VRGGLAGEFSSEDAVAMAAMVRTSRLP...MQE.IAL..KLGQ.ET......GVR.VEI..AG..V..EAHM.A.ILG..ALTTP.......GT.S.R.PLAILDLGGGSSDAAVIG..RDGQI..N..A..V.H.L.A.G...A..G....D....M....VT....MLI......A..S......E..L....G......LE.D.....RSVAEDIK.R.HPAAKVESLFHLRLEDGTVRFFE.EPLDSRLFARVVIL.KE.HDMIPV..PGRHSLEKVRTVRRDAKRKVFVTNAIRALAQV..APAGNLRLI.DFVVMVGGSALDFEIADLLSDALAAYG..VVAGRGNIRGSEGPRNAVATGLVLSY..................................................................................................
A0A162S1V9_9CLOT/272-599             ............................................................................................................................................IGIEQGSSAIMDSLSEVWPLQDVTGEPGTNVGGMIERVRQVMGELT.GQ..................NIEEIKIQDILAVDTFIPQK.........VQGGLAGEFALENAVALAAMVKTSKLP...MET.IAK..KLQG.ET......GVK.VLI..GG..V..EANM.A.VLG..ALTTP.......GT.D.K.PLVILDIGGGSTDSAYIN..KDESV..K..S..I.H.H.A.G...A..G....E....M....VT....MLI......K..S......E..L....G......LE.D.....YNLAEDIK.K.HPLAKVESLFNIRYEDGSVCFFQ.QPLDASLFARNIIV.KS.DEMIPI..PTRHAIEKIKMVRREAKRKVFVTNVIRALKDV..APNKDLRSI.DFVVLVGGSALDFEIPEIISDELSHYG..VVCGSGNIRGNQGPRNAVATGLVISY..................................................................................................
A0A0F2Q594_9CLOT/275-603             ............................................................................................................................................VDIEEGSEVIMSIVKKITPLNDVHGESGSNVGGMIEKVRNVMSNLT.NQ..................PRGQMKIQDILAVDTIVPQK.........VTGGLAGEFSLENAVGLAAMVKTNRLP...MEQ.IAE..KLAK.EL......GIE.TVI..AG..V..EANM.A.LLG..ALTTP.......GT.A.K.PLAILDLGGGSSDAAIIT..NNNKT..S..S..V.H.L.A.G...A..G....D....M....VT....MLI......N..T......E..L....G......LE.N.....LHLAEEIK.K.YPLGKVESLFHVRLEDGTVKFFD.KSLPPQFFARTVII.KGqDDMVPI..QAKHSLEKIRAVRREAKHKVFVINAVRALEQI..SLTGNIRYI.QYVVLVGGSALDFEIPEMISNALAGYG..IVCGQGNVRGMEGPRNAVATGLVLS-i.................................................................................................
D1AFL7_SEBTE/275-602                 ..........................................................................................................................................ag--IEEGAERIMTGVESVQCVTDVRGEPGTNVGGMLEKVRQTMASLT.KK..................LPSDIYIQDLLAVDTFVPVN.........IKGGLANEFSMENAVGIASMVKSDRLQ...MQI.IAE..ELEK.EL......GVK.VEI..GG..V..EANM.A.IMG..ALTTP.......GT.D.S.PLAIVDMGAGSTDASIID..RQGRI..F..S..V.H.L.A.G...A..G....N....M....VT....MLI......N..S......E..L....G......LA.D.....TGLAEDIK.I.YPLAKAESLFHIRHEDGTVQFFK.EALKPEVFARVVVL.KE.DEMLPV..PGEHSLEKIKAVRRSAKERVFVKNAIRALEFV..SPTGNIRDI.PFVIMVGGSALDFEIPELVTDRLAKYS..IVAGRGNIRETEGPRNAVATGLILD-i.................................................................................................
W1FQ41_ECOLX/232-488                 ............................................................................................................................................VDVAAGAEAIMKAVGECPKLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSHEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAQ..EITQ.KL......NID.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..PKGEI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LD.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPTVFARVCVV.KP.DELVPL..PGELALEKVRAIRRSAKERVF-----------..---------.---------------------------..--------------------------ry................................................................................................
A0A0C1LF12_9PSEU/285-630             ............................................................................................................................................VGIDAGAEEIMATLRRVAPLSDATGESGTHVGGXLAAVRDAMTETL.ADapdthdapdspdapdartGGQDVRIQDILAVDTFVPQH.........VTGALAGEFALENAVALAAMVRTSRGP...MEA.LAE..QIRA.AL......GTD.VVV..GG..V..EADM.A.VLG..ALTTP.......GT.E.R.PVAILDLGGGSTDAALAM..PGGDV..T..S..V.H.L.A.G...A..G....D....L....VT....KLI......D..S......E..L....G......LE.N.....RELAEDIK.R.HPLAKSESFFHVRMEDGTARFFD.EPLPADAFARVVVL.GE.EGMRPI..PTRHSLEKIRQVRRSAKHKVFVVNAVRALERV..APGGNLREI.GFVVVLGGSALDFEIPDLIAEAVAGSG..IVCGTGNVRGSQGPRNAVATGLVA--eh................................................................................................
A0A0R1RN13_9LACO/276-604             ............................................................................................................................................VDLTAGADKIMAAVSTFNHIDNVVGEAGTNIGGMLERVRQTMAELT.NK..................SLSEIAIQDLLAVSTSVPID.........VKGGLAGEFSMEQAVGIASMVKSDHLQ...MAM.IAT..EIKK.AF.....qDVT.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.S.A.PMAILDLGAGSTDASIIN..AKGET..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......ID.D.....QYLAEDIK.K.YPLAKVESLFFIRHEDGSVQFFD.KALSGNLFAKTVVD.TP.TGFVPI..PGDLSIEKIKNIRQTAKKRVFVANAIRALKHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRAIEGPRNAVATGLILAY..................................................................................................
A0A098Y1Y5_9ACTN/273-606             ............................................................................................................................................IDVDAGAEAIMATVARLQPLDDVHGEPGTHVGGMLAQVRDTMSDVL.RGadg............aaqPASEIAIRDVLAVDTFVPAE.........VRGGLAGEIALENAVALAAMVRTSRSR...MQL.VAD..QVSA.EL......GAR.AEI..GG..V..EGEM.A.VGG..ALTTP.......GV.D.R.PVAVLDLGGGSTDAALMT..VDGVC..T..A..V.H.V.A.G...A..G....E....L....VT....KLI......D..S......E..L....A......LG.D.....REVAEGVK.W.HPLAKVESFFHLRHEDGTVQFFD.QPFPPHVFARVVVL.TP.DGPVPV..ETRHGLDHVRRVRRAAKSRVFVVNAVRALRQV..APGGDLRAL.DFVVLLGGSALDFEIPELIADELAPYG..IVCGTGNVLGTQGPRNAVASGLVR--ah................................................................................................
U7VEM7_9FUSO/277-602                 ............................................................................................................................................VGIQEGAEKIMEKIS-FLNVQDIFGEDGTNVGGMLRNVKNTMSKFT.GE..................NIEDIKIKDLLAVDTFVPQR.........IKGGLAGEFMLENAVGLAVMVGTEKNQ...MEN.LAR..LIKS.EL......GIE.VEV..GG..V..EADM.A.IKG..ALTTP.......GT.G.K.PLAIIDIGAGSTDACSID..KFGRK..A..H..T.H.L.A.G...A..G....N....M....VT....LLI......Q..K......E..L....G......VE.N.....FNLAEDIK.K.YPLAKVESFFHIRYEDGSVQFFN.EPLSPSIYAKNVLV.KN.GELIPI..DIQNTLERIRDIRRESKRRVFVANSERALKKI..SLTKNIRDF.EFVIIVGGSALDFEIPEMITEALSKYG..VVAGCGNIRGIEGPRNAVATGLVL--g.................................................................................................
A0A161ZII4_9EURY/276-604             ............................................................................................................................................VDTEDGAHVIRETVRNRRPLEDVTGESGTNIGGMLNRARTEMSEIT.NQ..................DPDSIQIRDILAVDTIVPQA.........VKGAVAGEYRMENAVALASMVKTNRLP...MEQ.IAG..ELTE.EL......AVD.VHI..QG..I..EASM.A.VLG..SLTTP.......GT.D.F.PIAILDIGGGSTDAAYMN..ERKEI..E..S..I.H.L.A.G...A..G....D....L....VT....MLI......D..S......E..L....G......LE.D.....RKTAEEIK.K.HPAAKVETLFSIRHEDGTVDFLE.TAVDPELFGKVVLL.QDdDGMEPI..DTDHSLEEIRATRREAKEKVFVTNSKRALRQI..TPSLNIRHL.PFVVMVGRSALDFEIPEMISNTLAEYG..IVCGSGNIRKEQGPRNAVATGLVLS-h.................................................................................................
A0A0R1XEN2_9LACO/279-606             ............................................................................................................................................VDVAAGSDKIMDTVSDFRSIQDITGESGTNVGGMLEKVRQTMADLT.GK..................QNKDIAIQDLLAVDTQVPVK.........VRGGLAGEFSNESAVGIAAMVKSDHLQ...MEM.IAK..LIEQ.EF......HTK.VEI..GG..A..EVES.A.IRG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..KENKT..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LE.D.....PYLAEDIK.R.YPLAKVENLFQIRHEDGSVQFFD.KPLDSGLFARVVVI.KP.EGYEPI..PGNPSIEKVKMIRQSAKKRVFVTNAIRALRIV..SPTGNIRDI.PYVVIVGGSALDFEIPQLVTDELAHYN..LVAGRGNVRGVEGPRNAVATGLVLRY..................................................................................................
E4RMA0_HALHG/276-603                 ............................................................................................................................................IGIDAGAEEIMDSLEKIHPIEDVKGQPGTNVGGMLDRVKVTMSKVT.DQ..................PLEDIRIKDILAVNTFVPKE.........VKGGLAEEYAMENAVGLAAMVKTSQLP...MRK.IAD..KLED.ET......NVE.VEI..AG..V..EANM.A.ILG..ALTTP.......GT.D.K.PFVILDMGGGSTDAAMVT..NRDNI..Y..T..T.H.L.A.G...A..G....D....M....TS....LLI......N..I......E..L....G......LG.D.....INLAELIK.K.NPLAKVESVFHVRHEDGSVSFFD.EPLAPKLFGRVIIL.SD.DDKIPI..PTDHSLDKIRQVRRDAKNDVFVRNSIRALKRI..IPTGNIRDI.DFVVMVGGSAIDFEIPTMISNQLSEYG..VVAGRGNIRGVMGPRNAVATGLVLSY..................................................................................................
J2DGG7_KLEPN/277-604                 ...........................................................................................................................................a-DVAEGAEAIMQAMSACAPVRDIRGEPGTHAGGMLERVRKVMASLT.GH..................EMSAIYIQDLLAVDTFIPRK.........VQGGMAGECAMENAVGMAAMVKADRLQ...MQV.IAR..ELSA.RL......QTE.VVV..GG..V..EANM.A.IAG..ALTTP.......GC.A.A.PLAILDLGAGSTDAAIVN..AEGQI..T..A..V.H.L.A.G...A..G....N....M....VS....LLI......K..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYG..VVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
A0A0F3RTY4_9LACO/276-603             ............................................................................................................................................VNVAAGAEAIMKKINEFDRIQDITGESGTNVGGMLEKVRQTMADLT.AK..................QNREIAIQDLLAVNTSVPVK.........VRGGLAGEFSTEEAVGIAAMVKSDHLQ...MQL.IAN..LIQD.EL......NIP.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..KQNQI..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....VYLAEDIK.K.YPLARVENLFQIRHEDGSVQFFD.KPLPSEIFARTVVI.KP.DGYVPL..PGNLNIEKVKTIRQTAKKRVFVENAQRALKHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRSVEGPRNAVATGLILSY..................................................................................................
T0C8S1_ALIAG/276-603                 ............................................................................................................................................VSVNDGSDAIMEAYEKIGSLVNVVGETATNVGGMLNSLRQNLAQLT.QQ..................SPSEITIRDLLAVDAVVPMS.........VSGAMAGELTLETGVAFASMVKTSRLP...IQK.VAD..TLAQ.AI......GVP.VEV..GG..V..EAEM.A.IRG..ALTTP.......GT.R.K.PIVILDMGGGSTDAAMMA..ENGKI..T..S..T.H.L.A.G...A..G....D....M....VT....MLI......D..M......E..L....G......LN.N.....KALAEKIK.K.YPLAKVMSMFHMQLEDGTTMFSD.APLPPDTFGRVVIR.EG.EDLVPL..NIKVTMEKVREIRRTAKKRVFVTNGLRALRRV..VPTGNLKHL.SFVVMVGGSALDFEIPQMLTEEMSKYG..IVAGFANVRGTEGPRNAVATGLVLA-c.................................................................................................
A0A117L7W0_9FIRM/273-602             ............................................................................................................................................VDVDEGADAICAAVESIWPLEDAEGTPGTNAGGLLAKVKETMADVT.GR..................SPSEIRIQDIHAVDTLVQQK.........VKGGLADEFFSEHAVALAAMVRSSRLP...MEK.VAA..KIEE.DL......GIR.VEI..AG..V..EANM.A.ALG..ALTTP.......GA.S.T.PLAILDLGGGSTDAAYITdiKQEKV..D..T..V.H.L.A.G...A..G....D....M....VN....MLI......A..T......E..L....G......LS.D.....RTLAEDIK.R.YPLAKVESLFSIRLEDGTVRFFE.EPLDARVFARVVLL.KE.DGLVPI..PVDASLEKVRMVRREAKRRVFVRNALRALAKV..APAQNVRLL.DYVVLVGGSALDFEVPEMISDALAGYG..VVVGRANVRGVEGPRNAVATGLVLA-g.................................................................................................
A0A0L6U0P1_9FIRM/274-601             ............................................................................................................................................INVDDGAERIMEAIRSVAPVEDIKGEPGTNAGGMLEKVRQVMSNLT.EQ..................LPATIKIQDLLAVDTFVPQV.........VKGGMAEEFSMENAVGIAAMVKADKLQ...MNM.IAE..ELEK.EL......GIK.VEV..GG..V..EANM.A.VRG..ALTTP.......GS.N.K.PLAIIDMGAGSTDAAIIN..RAGEI..K..S..I.H.L.A.G...A..G....N....M....VT....MLI......G..S......E..L....G......FE.D.....MGISEDIK.K.YPLAKVESLFHIRHEDGTVQFFD.KPLDPQTFARVVIL.TP.NRMVPI..PGNYSLDRIRTVRREAKTKVFVVNAIRSLERV..SPTGNVRDI.EFVTLVGGSALDFEIPQLVTDALSKYS..IVAGRANIRAIEGPRNAVATGLVLAY..................................................................................................
Q03Q33_LACBA/276-603                 ............................................................................................................................................VNVAAGAEAIMKKVNQFDRIQDITGEAGTNVGGMLEKVRQTMADLT.NK..................QNRDIAIQDLLAVNTAVPVK.........VQGGLAGEFSTEQAVGIAAMVKSDHLQ...MQQ.IAD..LIQD.EL......HIS.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..QQDDI..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....VYLAEDIK.K.YPLARVENLFQIRHEDGTVQFFE.DPLPADIFARTVVI.KP.DGYVPL..PGNMNIEKVKQIRQTAKKRVFVENARRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRAVEGPRNAVATGLILSY..................................................................................................
F9ELP3_FUSNU/274-601                 ............................................................................................................................................VSLDNGAEAIMSVLEQCYPVIDIWGEKGTNAGGMLERVRIVMAQLT.NQ..................DPKNIKIQDLLAVNTFVPQK.........VKGGIAEEFSMENAIGLAAMVKADKLQ...MEM.IAT..ELQN.KI......NKK.VVV..GG..V..EAEM.A.IIG..ALTTP.......GT.A.K.PLAIIDMGAGSTDASIMT..ADNKI..S..S..C.H.L.A.G...A..G....N....M....VT....MLI......D..K......E..L....G......IN.N.....IELSEDIK.K.YPLAKVESLFHIRHEDGSVQFFE.EALDPRVFARIVIL.KE.GNMIPL..DSNQNLEKIKNVRREAKEKVFVTNTLRALKKV..IPSGNVRDI.DYVVLVGGSALDFEIPQMVTEALSHFG..VVAGKGNIRGVEGPRNAVATGLALSY..................................................................................................
B8FDN6_DESAA/272-599                 ............................................................................................................................................VDVELGADAIMEKLARVAPLKEIQSQPGTNAHGMFERVRTVMAELT.DQ..................PVSLIKIQDVLAVNTLQPQH.........VLGGLAGEFTRGTAVGLAAMVMTQNIP...MQR.LAA..KLKE.ET......GVE.VEI..GG..V..EAEM.A.ITG..ALTTP.......GA.E.A.PLAILDLGGGSTDASIIH..RDGTV..K..S..I.H.M.A.G...A..G....D....M....VT....MLI......N..T......E..L....G......LD.D.....PDLAEDIK.R.YPLAKVETLFHMRHETGAVEFFD.AHLDPSLFGRVAIL.GE.NGPIPI..MHDLNLNQIVNVRRKAKEKVFVRNALRALEQV..APGGNIRLI.DFVALVGGSALDFEIPEMIADALAEYG..PVLGKGNIRGCEGPRNAVATGLCLS-r.................................................................................................
R5XK30_9FIRM/273-600                 ............................................................................................................................................VNIDTGADSIMETLQKAGQIRDISGQQNTNVGNMLDRIKKSMTDVA.SD..................RDQEVRITDILAVDTLAPVE.........ISGSLAGETCMEKAVGIAAMVKTKHLP...MQK.IAE..KLEQ.EL......KVK.AVV..AG..V..EAVM.A.SLG..ALTTP.......GT.R.L.PLAILDMGGGSTDAAVLE..ENGTV..R..T..T.H.Q.A.G...A..G....E....L....VT....MLI......Q..T......E..L....G......LG.S.....RTTAEQIK.K.YPMGKVESLFHMRLENGSMQFFE.ESIDPGYYGHVVLL.AP.GEMLKV..EEDIPMEKILEVRREAKRKVFVRNAVRALKIV..APEHDLRKI.SNVVLVGGSAEDFEIPEMLTEALAEYR..IVCGRGNIRGTEGPRNAVATGLLMSY..................................................................................................
A0A0P0SF11_9PSEU/274-601             ............................................................................................................................................VGVDDGADAIMDAVARVAPLTDVHGEPGTHVGGMLANVRDTMTDVT.GQ..................PASEIRIRDVLAVDTVVPAA.........VRGGLAGEVSRENAVALAAMVRTSRSR...MQA.VAS..ALAA.EL......GCD.TVI..GG..V..EAEV.A.VRG..ALTTP.......GS.S.V.PIAIVDMGGGSTDAALLD..ADGTV..S..T..V.H.V.A.G...A..G....E....L....VT....RLI......G..S......E..L....G......ID.D.....REAAESVK.R.HPLAKVESFFHVRHEDGSVQFFG.EPLPPHVFAKVVTV.TP.DGLAAV..PVRGSLEEVRRVRRAAKQRVFVVNALRALAQV..APQGSLRLL.GSVVLLGGSALDFEIPAMVADALAPYG..VVCGIGNVHGTEGPRNAVAAGLVD--ah................................................................................................
C6PYA4_9CLOT/272-599                 ............................................................................................................................................VSIEEGSEGIMKNLGEVWPLNDVSGESGTNVGGMIERVRQIMGELT.SQ..................NIEDIKIQDILAVDTFKPQK.........VQGGLAGEFALENAVALAAMVKTSKLP...MEN.IAR..KLQE.ST......GIK.VVI..GG..V..EANM.A.VLG..ALTTP.......GT.D.K.PLVILDMGGGSTDSAYIS..KEGKV..K..S..I.H.H.A.G...A..G....E....M....VT....MFI......N..S......E..L....G......LD.D.....YNLSEDIK.K.YPLAKVESLFNLRYEDGTVCFFQ.QPLDASLFARNVVV.KN.DEMIPI..PTKDSLEKIRLVRRDAKKKVFVTNAIRALGDT..APNGNLRSI.EFVVLVGGSALDFEIPEMVSEELSHYG..IVCGSGNIRGIEGPRNAVATGLVLSY..................................................................................................
G2G2A6_9FIRM/275-602                 ............................................................................................................................................IEVDAGAAKIMETVERVQPVLDVQGEAGTNVSGMLERVRQVMSELT.AQ..................PLGEMKIQDVLAVDTFIPKK.........VQGGLAGEFALENAVALAAMVKTSRLP...MQQ.IAD..QLMQ.SL......GLR.VVI..AG..V..EAGM.A.IHG..AFTTP.......GT.A.K.PLAILDMGGGSTDAAIIT..RDEQV..L..S..I.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LN.D.....FNLAEDIK.K.YPLAKVESLFHIRLEDGTVQFYE.HHLPPEVFSRVVIL.KD.GEMVPI..PTNHPLDKVRHVRRESKKRVFVINSLRSLARV..APTGNIRHI.DFVVLVGGSALDFEVADMVTDALAEYG..IVCGRGNIRGSEGPRNAVATGLVLSY..................................................................................................
W1E9D1_KLEPN/275-602                 ............................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVAGEAGTNIGGMLEHVRQTMAELT.NK..................PAQEIRIQDLLAVDTAVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAL.IAR..EIEH.KL......QIA.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..AQGEI..S..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.SALPPTVFARVCVV.KP.DELVPL..PGDLPLEKVRAIRRSAKSRVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYR..LVAGRGNIRGCEGPRNAVASGLLLSW..................................................................................................
A0A0Q5VG80_9ACTN/279-607             ............................................................................................................................................VDVDAGAEAIMAALARVQPLEDAHGEPGTHVGGMLAAVRDTMADTLgGA..................DPGDIAIRDVLAVDTFVPAE.........VRGGLAGEIALENAVGLAAMVRTSRSR...MQA.VAD..RVAT.SL......TTT.TEI..GG..V..EGEM.A.ALG..ALTTP.......GV.Q.A.PVVVVDLGGGSTDAALLT..ADGTS..T..A..V.H.V.A.G...A..G....E....L....VT....KLI......D..S......E..L....A......LG.D.....REVAELVK.R.WPLAKVESFFHVRHEDGTVQFFD.EPLPPHVFARVVAL.TA.EGPVPI..GTRYGLDHVRRVRREAKRRVFVVNTLRALRQV..APGGELRAL.DFVVLLGGSALDFEIPDQIADALAGHG..VVCGTGNVLGDQGPRNAVATGLVAA-f.................................................................................................
H6LEQ0_ACEWD/273-600                 ............................................................................................................................................VNVDDGAEKIMEAIRTVAPIEDIKGEAGTNAGGMLEKVRQVMSNLT.DQ..................LPSAIKIQDLLAVDTFVPQT.........VKGGIAEEFSMENAVGIAAMVKADKLQ...MNM.IAH..ELEA.EL......GVK.VEV..GG..V..EADM.A.IRG..ALTTP.......GS.N.T.PLAIIDMGAGSTDAAIIN..KAGEI..K..S..I.H.L.A.G...A..G....N....M....VT....LLI......A..S......E..L....G......YD.N.....MALAEDIK.K.YPLAKVESLFHIRHEDGTVQFFD.KPLDPRTFARVVIL.TP.NGMIPM..PGNYSLERIRAIRREAKTKVFVVNALRSLERV..SPTGNVRDI.EFVTLVGGSALDFEIPQLVTDALAKYS..IVSGRANIRGVEGPRNAVATGLVLAY..................................................................................................
E6MIY1_9FIRM/273-600                 ............................................................................................................................................IDVDAGADEIMEAVRTVAPIGDVTGEPGTNAGGMLERVRQVMSNLT.KQ..................TPDKILIQDILAVDTFVPKR.........VQGGMANEFSMENAVGIAAMVRADKLQ...MGM.IAD..ELEK.EL......GIK.VEV..GG..V..EAEM.A.IHG..ALTTP.......GA.N.K.PMAILDMGAGSTDAAIIN..RAGEI..H..F..I.H.L.A.G...A..G....N....M....VT....MLI......G..S......E..L....G......LD.D.....RGIAEDLK.K.YPVARVESLFHIRHEDGSVQFFD.SPLDPRTFARTVIL.TP.NGMSPL..PGDITVERVRQVRQDAKRKVFVVNAIRALERV..SPTGNARDI.EFVTMVGGSALDFEVPQLITDALSRYS..IVAGRANIRATEGPRNAVATGLVLAY..................................................................................................
W1G4Q8_ECOLX/273-600                 ...........................................................................................................................................a-DVAQGAQAIMQAMSACAPVRDIGGEAGTHAGGMLERVRKVMASLT.GH..................DMNTVHIQDLLAVDTFIPRK.........VQGGIAGECSMENAVGIAAMVKADRLQ...MQA.IAS..ELSA.RL......NTP.VEV..GG..V..EANM.A.VAG..ALTTP.......GC.A.A.PLAILDLGAGSTDAAIIN..SDGVV..R..A..V.H.L.A.G...A..G....N....M....VS....LLI......Q..T......E..L....G......LN.D.....AFLAEEIK.K.YPLAKVESLFSIRHENGAVEFFR.EPLSPTVFAKVVYL.KE.GELIPV..DNLTSLEKIRLVRRQAKEKVFVTNCLRALLQV..SPSGSIRDI.AFVVLVGGSSLDFEIPQMITDALAHYG..VVAGQGNIRGSEGPRNAVATGLVLA-g.................................................................................................
A1UN21_MYCSK/264-567                 ............................................................................................................................................VDCRIGGEIVRYAPAAAHTV--LRLEPPGCAVEV--RLSALPAAEN.GI..................AVDDAFFTDLASIDNGAWLRrgvadargtVVALLAAEPVTDAAATLSGLT------...---.---..----.--......GRP.ART..VA..G..EPAA.A.ARG..AQTTP.......GL.P.P.GSVVCDIGGGTVD--LIG..QGRTV..T..A..-.-.-.A.G...A..G....E....T....IT....TAV......S..R......V..L....G......I-.P.....RALAERVK.R.TPALRVEGPHVAHEEDGRRVFLD.SPASADAIGRLCTR.GS.AGLVPF..SHRLAAEEWRSLRLAIKQQTVAANIARCLATFdePPS------.-ALVLAGGGALDDELLRTVGESLRPAR..VVVGRADIDGVHGPRFAVASGLVHLY..................................................................................................
A0A101EFQ8_9BACT/278-606             ............................................................................................................................................VNVEDGAEAIMKALADSQPVRDIFGQPGTNVGGMMERVRRTMSNLT.GL..................PVSDVHIKDLLAVDVLVPQR.........IVGGIAGEFSNEHGVAIAVMVEAQKLP...MQR.LAE..AIRE.ET......GVE.VVV..GG..V..EAEM.A.VRG..ALTTP.......GT.K.R.PIAILDLGAGSTDASFMK..ENGDI..E..L..I.H.L.A.G...A..G....N....M....VN....TII......A..S......E..L....A......IE.D.....MELVESIK.R.YPLCKVESPFHIRHEDGKVSFLD.TPLSPNLFGRLALM.VTdDLFIPL..DLDLPLERVREIRRRAKREVFVTNALRALEKV..SPAGNVRLL.EYVVLVGGSALDFEIPAMITDTLARFG..VVAGKANIRGSEGPRNAVATGLVLAY..................................................................................................
A0A0M2K4E0_9MYCO/260-563             ............................................................................................................................................VEIHVDGATVRYTPAQAHAV--LRRSVPGSVKRV--RLQSVPSAAD.SL..................AVHDAFFTDLATIDNGAWLRrgvvdahgtVVALLAAEEAADAAARLSELT------...---.---..----.--......GRP.ART..LA..S..EPEA.A.AWG..ARTTP.......GF.P.P.DAMVCDIGGGTVD--LIG..AEATV..V..A..-.-.-.A.G...A..G....E....S....IT....VAI......A..Q......V..L....G......I-.P.....QALAETVK.R.TPAIRVEGPHVAHEEDGRRVFLD.APASSDAIGRLCTR.GS.AGLVPF..SNRLAAEEWRSLRLAVKQETVAANIARCLTAFdePPR------.-ALVLAGGGALDDELMRTVAEALRPAR..VVVGRAHIDGVHGPRFAVARGLVA--lf................................................................................................
W1E5Z1_KLEPN/1-162                   ............................................................................................................................................----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....M....VS....LLI......K..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYG..VVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
A0A095XCV6_9FIRM/275-601             ............................................................................................................................................VDVEDGAEAIMKKEASVGRIIDIKGEAGTNAGAMLERVRNTMASLT.KK..................RYEDISIQDLLAVDTLSPQT.........IRGGLAGESALEAAVGVAAMVRSDRLQ...MNR.IAK..ELEE.GL......HIP.VVV..GG..V..EADM.A.IRG..ALTTP.......GT.D.I.PLAILDLGAGSSDASIMN..DRREI..E..R..I.H.L.A.G...A..G....N....M....VS....LLI......Q..T......E..L....G......LA.S.....FEEAEEIK.I.YPLAKVESMFHLRHENGSVEFFD.EMIDPHLFARVVLV.TP.EGLKPV..NSKYSIERIKHIRQEAKSKVFVTNALRALESI..APLGNVRSL.EHVVLVGGSALDFEVPQLITDSLAEYG..VVAGRGNIRGTEGPRNAVATGLLL--g.................................................................................................
H1LI38_9LACO/276-603                 ............................................................................................................................................VDVAAGAEAIMKTVNEFDSIDDITGKSGTNVGGMLEKVRQTMADLT.GK..................QNQDIAIQDLLAVNTSVPVK.........VTGGLAGEFSMEQAVGIAAMVKSDHLQ...MQI.IAN..LIEQ.DL......HVP.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.S.K.PMAILDLGAGSTDASIIN..KEDKK..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....IYLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KPLPSNLFARVVAI.KP.VGYEPL..PGNLSIEKVKIVRQTAKKRVFVTNALRALRHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDALSHYN..LVAGRGNIRSIEGPRNAVATGLILSY..................................................................................................
F9DQU4_9BACL/277-604                 ............................................................................................................................................VDINDGADEIMGSYKNIGVLNDVQGEQGTNAGAMLNGLRQDLAEVT.DQ..................HMHEIRITDLLAVDTKIPSS.........IRGALAGEITMESGVGLASMVQTKKTS...IQA.VSS..LLEE.EL......GVS.VEV..GG..I..EAEM.A.IAG..ALTTP.......GT.E.R.PIVILDMGGGSTDAATND..ENGRI..R..T..V.H.L.A.G...A..G....D....M....VT....LLI......N..T......E..L....A......LH.D.....LELAEKIK.K.YPLGKLQSLYHMQLEDGTYLFSE.EPHPPEAFGKVVIR.EE.KGITPL..PIRHSLEKIRTIRREAKRKVFVTNAIRALEQV..LPTHNIRHI.SFVVMLGGSALDFEIPEMINDELSKYG..IVAGFANIRGTEGPRNAVATGLVLS-t.................................................................................................
W1FRT9_ECOLX/1-80                    .........................................................................................................................................mlr----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....-....--....---......-..-......-..-....-......--.-.....--------.-.-----------------------.--------------.--.------..-----------------NAFFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYR..LVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
A0A0R2EGJ7_9LACO/277-604             ............................................................................................................................................VNVAAGADAIMKKINEFDNIADIAGESGTNVGGMLEKVRQTMAELT.GK..................QNSEIAIQDLLAVNTSVPVT.........VRGGLAGEFSMEEAVGIAAMVKSDHLQ...MQQ.IAD..LIQG.EF......HVP.VEI..GG..A..EAES.A.ILG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..QKDEK..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LE.D.....PYLAEDIK.K.YPLAKVDNLFQLRHEDGAVQFFE.DPLPAELFARVVAV.KP.DGYEPL..PGNLSIEKVKIVRQTAKKRVFVTNAIRSLHHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRAVEGPRNAVATGLILSY..................................................................................................
A0A100W353_9MYCO/259-562             ............................................................................................................................................VEFTVDGRPVRYSPAQAHSI--LRRDPPGDPLRI--RLRSIPTADH.EI..................TVDDAFFTDLSALDNGAWLRrgvadargtVVALLAADHVAD---------------...---.AAA..TLQE.LT......GRP.AYT..IA..S..EPEA.A.ARG..ARTTP.......GL.P.P.NSVVCDIGGGTID--LVG..VDRTV..T..A..-.-.-.A.G...A..G....E....T....IT....VAV......A..R......M..L....N......I-.P.....RALAERVK.R.TPALRVEGPHVAHEEDGRRVFLD.HPAPADAIGRLCTR.GS.AGLVPF..SNKLAAEEWRSLRLAIKQETVAANIARCLGAFekPPTA-----.--LVLAGGGALDDELLRTVGESLRTVP..VVVGRANIDGVHGPRFAVASGLVHLY..................................................................................................
D9S1P8_THEOJ/273-600                 ............................................................................................................................................VDLEEGADKVMQALEQVWPLVDVEGTPSTNVGGLIARVKEVMGQVT.YQ..................DMRKIKIQDILAVDVLVPQR.........VTGGIAEEFFTEDAVAVAAMVKSSKLP...MEK.IAE..KVER.EL......NIP.VEI..AG..V..EANM.A.VLG..ALTTP.......GT.D.V.PVAVLDLGGGSTDAAFMN..RKKEV..V..S..I.H.M.A.G...A..G....E....M....VN....MII......A..A......E..L....G......LS.D.....RQLAEDIK.R.YPVAKVESLFSIRMEDGTVRFFE.KPLDPQTFARVCLL.KE.GSLVPL..PPDLQLEKVRQVRRKAKQKVFVSNAVRALSKV..APSGNLRLI.DFVIMVGGSALDFEIPEMISEALAGYG..IVAGRGEIRGSEGPRNAVATGLVLS-g.................................................................................................
A0A100VWP8_9MYCO/280-518             ....................................................................................................................gsvvadslvmatldsgdrapadvd----------------------------------------------.--..................--------------------.........---------------------------...---.---..VLGA.AL......GVP.VTR..ID..S..EAAA.A.RAG..ALTTP.......GA.T.A.DVVVVDVGGGTVD--VVT..DDTRI..A..-..-.-.L.P.G...A..G....Q....L....LT....SAT......A..T......A..L....D......I-.S.....RSAAEYAK.R.AESLTAITVQLVEDEHGRRQFLD.KPLDGRCTGWLLTS.AP.SGLLPF..TSRLTGAEWRSWRLAAKRTVIGGNVMRGIEKV..APDA-----.GGVLLVGGGAGDDELVRAVSEQLGH-R..VAVGRGNVRGQLGHRFAVAYGLVA--la................................................................................................
E3GH67_EUBLK/273-600                 ............................................................................................................................................VNVDEGAEIIMDAIRSVAPVEDVKGEAGTNAGGMLEKVRQVMSNLT.EQ..................NPQNIKIQDLLAVDTFVPQS.........VKGGMADEFSMENAVGIAAMVKADKLQ...MNM.IAE..VLEK.EL......NVK.VEV..GG..V..EADM.A.IRG..ALTTP.......GS.N.K.PLAIIDMGAGSTDAAIIN..RAGEI..H..S..I.H.L.A.G...A..G....N....M....VT....MLI......G..S......E..L....G......FE.D.....SGLAEDIK.K.YPLAKVESLFHIRHEDGTVQFFD.EPLDPRSFARVVIL.TP.SGMVPI..PGNHSLERIRTVRREAKTKVFVVNAIRSLERV..SPTGNVRDI.EFVTLVGGSALDFEIPQLVTDALSKFS..IVAGRANIRSVEGPRNAVATGLVLAY..................................................................................................
A0A162SCA6_9CLOT/279-606             ...........................................................................................................................................a-DVEDGAEKIMEAVKLCVPVQDIKGEAGTNAGGMLEKVRQVMAKLT.NQ..................KITDIKIQDLLAVDTFIPQK.........VKGGLAEEFSMENAVGIAAMVKADKLQ...MQM.IAD..RLQE.KL......KVA.VEV..GG..V..EADM.A.IRG..ALTTP.......GS.S.T.PLAILDMGAGSTDASIIN..SQGQI..C..S..I.H.L.A.G...A..G....N....M....VT....MLI......K..S......E..L....G......LE.D.....FNLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.NPLEPSVFAKVVIL.KD.GMLIPI..DGQNSLEKIKTIRRSAKEKVFVTNCLRALSIV..SPTGNIRDI.EFVVLVGGSSLDFEVPQLVTDALAQYG..VVAGRGNIRGVEGPRNAVATGLILA-f.................................................................................................
D2S4X8_GEOOG/285-618                 ............................................................................................................................................VDVDAGAEAIMEVVGRAQPLDDARGEPGTHVGGMLAQVRDTMADVM.DVagq............pdvPVSDIAIRDVLAVDTFVPAE.........VRGGLAGEVALENAVALAAMVRTSRSR...MQL.VAD..LVSE.GL......GAA.AEI..GG..V..EGEM.A.VGG..ALTTP.......GV.D.R.PIAVLDLGGGSTDAALLT..REGEC..T..A..V.H.V.A.G...A..G....E....L....VT....KLI......D..S......E..L....A......LG.D.....REVAEGVK.W.FPLGKVESFFHLRHEDGTVEFVD.QPLPPHVFARVVVL.TP.DGPAPV..PTRHGLDHVRRVRREAKRRVFVVNALRALRQV..APGGNLRAL.EFVVLLGGSALDFEIPDMIADALAPHG..IVCGTGNVLGTEGPRNAVASGLVR--ah................................................................................................
A0A0H4QNK4_9LACO/276-603             ............................................................................................................................................VGLSGGADKIMDVVSSFDQIDNVTGEAGTNIGGMLERVRETMAKLT.DK..................QMDQIDIQDLLAVNTSVPIN.........VKGGLAGEFSMEQAVGIASMVKSDHLQ...MSM.IAD..EMEK.AF......GVH.VEI..GG..A..EAQS.A.ILG..ALTTP.......GT.S.A.PMAILDLGAGSTDASIIN..PDGES..V..A..I.H.L.A.G...A..G....D....M....VS....MII......N..S......E..L....G......LD.D.....IYLAEDIK.K.YPLAKVESLFFIRHEDGSVQFFD.KALPGNLFAKTVVV.KP.DGFVPV..PGDLNIEKIKTIRQTAKKRVFVENAIRALKHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRAIEGPRNAVATGLILSY..................................................................................................
J3ES93_9LACO/277-604                 ............................................................................................................................................VGISDGADKIMKVISSFKTIDDVTGEPGTNIGGMLERVRQTMAELT.GK..................QLNEIAIQDLLGVNTSVPIN.........VKGGLAGEFSMEQAVGIASMVKSDRLQ...MSR.IAK..EIEK.EL......NVK.VDI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..KENKI..V..A..I.H.L.A.G...A..G....D....M....VS....MII......N..S......E..L....G......LD.D.....PYLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KALPADIFAKTVVV.KP.TGYEPI..PGELSIEKIRIVRRTAKKRVFVANAIRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNVRSVEGPRNAVATGLILRY..................................................................................................
K0UJZ1_MYCVA/261-564                 ............................................................................................................................................VDIEVDSTIVRYSPAEAHRV--LRRSAPGSVRGV--RLRTVPTAAD.GL..................AVHDAFFTDLASIDNGAWLRrgvadtqgtVVALLAADEAEDAAATLSELT------...---.---..----.--......GRP.AQT..LS..T..EPEA.A.AWG..ARTTP.......GI.P.A.GAMVCDIGGGTVD--LIS..ADRTV..V..A..-.-.-.A.G...A..G....E....S....IT....VAV......A..R......V..L....G......V-.P.....SALAETVK.R.TPAVRVEGPHVAHEEDGRRVFLD.APASSDAIGRLCVR.GS.AGLVPF..SSRLAAEEWRSLRLAIKQEAVAANIARCLTAFdaPPTA-----.--LVLAGGGALDDELLRTVAEALRGAR..VVVGRADIDGVHGPRFAVARGLVAMY..................................................................................................
A0A0R1RGZ5_9LACO/277-604             ............................................................................................................................................VGISDGAEKIMKTVSDFKNIDNVTGESGTNIGGMLERVRQTMADLT.DK..................QMQDIFIQDLLAVNTSVPNN.........VKGGLAGEFSMEQAVGIASMVRTDHLQ...MQA.IAD..AIKD.EL......GVD.VEV..GG..A..EAEA.A.IRG..ALTTP.......GT.Q.A.PLAILDLGAGSSDASIID..KNGHI..V..A..I.H.L.A.G...A..G....D....M....TT....MII......N..S......E..L....G......LD.D.....PYLAEDIK.R.YPLAKVESLFYIRHEDGSVQFFK.KALPGTLFARTVVV.KP.DGYLPV..PGDLSIERIKAIRQSAKKRVFVTNALRALAKV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDALSHYN..LVAGRGNVRAIEGPRNAVATGLILSY..................................................................................................
C6PQK2_9CLOT/272-599                 ............................................................................................................................................IGIEQGSSAIMESLSEVWPLKDVTGESGTNVGGMIERVRQIMGELT.AQ..................NIEDVKIQDILAVDTFIPQK.........VQGGLAEEFALENAVALAAMVKTSKLP...MET.IAK..KLQD.ET......GVK.VLI..GG..V..EANM.A.VLG..ALTTP.......GT.D.K.PLVILDIGGGSTDSAYIS..KEGIV..K..S..I.H.H.A.G...A..G....E....M....VT....MLI......K..S......E..L....G......LE.D.....YNLAEDIK.K.HPLAKVESLFNIRYEDGSVCFFQ.QPLDASLFARNIIV.KN.EEMVPI..PTKHALEKIKMVRREAKRKVFVTNVIRALKDV..APNNDLRSI.DFVVLVGGSALDFEIPEIISDELSHYG..VVCGSGNIRGNQGPRNAVATGLVIS-h.................................................................................................
D7GD20_PROFC/273-600                 ............................................................................................................................................VDVDRGAQEIMHAAESVGTIRDIKGEPGTNIGGMMEKVRVTMGRLT.DR..................DPAGIEVTDLLAVDTNVPQK.........VTGGVAGEFSPEAAVGIAVMVKADRLQ...MQR.IAE..EMTE.QF......AVR.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.S.V.PIAILDMGAGSTDASVLR..EGQPA..R..S..V.H.L.A.G...A..G....N....M....VT....LLI......K..M......E..L....G......LD.S.....EEDAENIK.R.YPLARVETLFSIRHEDGTVQFFD.EPLAPELFARTVVL.HP.DGMIPL..PLRHPLEVIRQVRIHAKQRVFVTNAMRALAAV..SPTNNVRDI.AHVVLVGGSALDFEIPQFVTHALAEFR..VVAGRANTRGTEGPRNAVATGLVLA-w.................................................................................................
W1HST3_KLEPN/1-162                   ............................................................................................................................................----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....M....VS....LLI......K..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYG..VVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
S3X9M6_9ACTN/274-602                 ............................................................................................................................................VDVDSGADEIMQAASRMREIHDITGEPGTNVGGMMEKVRVTMGQLT.SQ..................HPRDIKITDMIAVDTMTPKQ.........VSGGLANEFSMENAVGIAVMVQADRLQ...MQA.IAQ..DIAA.QI......RIP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.S.A.PIAILDMGAGSTDASVMR..ADGTG..V..S..T.H.L.A.G...A..G....N....M....VT....LMI......Q..T......E..L....G......LD.A.....WDAAEDVK.R.HPLAKVETVFSIRHEDGSVQFFD.EPLPPHLYARVVVI.KPeEGLVPI..GVDLPVDAIRNIRIRAKERVFVANAVRALRRV..SPTDNVRDI.DFVVLVGGSALDFEIPQLVTKALAEYR..VVAGRANIRGTEGPRNAVATGLALSW..................................................................................................
A3CLC8_STRSV/275-604                 ............................................................................................................................................VDISKGADEIMEKIVYAGEISNVVGEAGTNVGGMLEKVRQTMADLT.EK..................EPSDIYIRDLLAVNTFAPIS.........VRGGVAGEFSMEQAVGIASMVNSDKLQ...MSI.IAQ..EVER.EL......GIT.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.D.R.PLAILDLGAGSTDASIID..SRGQI..L..A..V.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LE.N.....HHLAEDIK.R.YPLAKVESLFHIRHEDGTVQFFD.KPLSGDLFARVVIV.KEnDEFVPI.dDGDYSIEKIKLVRQSAKERVFVTNAVRALKRV..SPTQNIRDI.PFVVIVGGSALDFEIPQLVTEALSQHA..IVAGRGNVRGLVGPRNAVATGLILTY..................................................................................................
A0A0S2W4Y0_9FIRM/274-601             ............................................................................................................................................VDVDDGADRIMKAVESIPSLEDVRGEPGTNAGGMLEKVRQVMANLT.SQ..................HPKDIKIQDLLAVDTFTPQK.........VQGGLANEFSQENAVGIAAMVKADRLQ...MEA.IAR..EFAQ.QI......GVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.N.K.PLAILDMGAGSTDASIIN..AEGQI..H..S..I.H.L.A.G...A..G....N....M....VT....LLI......Q..S......E..M....G......LP.D.....FDTAEDVK.K.YPLAKVESLFHIRHENGTVEFFQ.QPLDPNLFAKVVIL.KE.GKLLPL..EGDWSMEKIRLIRQQAKQKVFVTNAIRALTRV..SPTGNVRDI.QFVVLVGGSALDFEVPQMVTDALSQYK..VVAGRGNIRGTEGPRNAVATGLVLS-l.................................................................................................
A0A0F5HML0_9BACI/274-601             ............................................................................................................................................VDVDEGAEKMMSVLTASAPIEDIKGEPGTNAGGMLERVRQVMSELT.SQ..................PPDAIKIQDLLAVNTFNPQM.........VKGGLAEEFSMENAVGIAAMVKADKLQ...MQM.IAD..ELQS.RV......DIE.VEV..GG..V..EADM.A.VRG..ALSTP.......GT.N.L.PVAIVDMGAGSTDASTMT..REGNI..T..S..V.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LD.D.....IDLAEDIK.K.YPLAKVESLFHIRHEDGAVQFFE.EPLEPHVFARVVIL.KD.GYMIPI..PGQHSIEKIRTIRRGAKEKVFVTNAIRALSMI..SPTGNIREM.EFVVLVGGSALDFEVPQLVTDALSQYG..VVAGRGNIRGTEGPRNAVATGLVLA-l.................................................................................................
A1TGM6_MYCVP/268-571                 ............................................................................................................................................VDVRVDGALVRYTPAEAHGV--LRRSVPGCVNAI--RLRSVPTAAS.GL..................SVHDAFFTDLGSIDNGAWLRrgvadaqgtVVALLAAEEADDAAASLSELT------...---.---..----.--......GRP.ART..LS..S..EPEA.A.AWG..ARTTP.......GL.P.P.GSMVCDIGGGTVD--LIG..ADGTV..V..A..-.-.-.A.G...A..G....E....S....IT....VAV......A..R......V..L....G......I-.P.....HALAETVK.R.TPAVRVEGPHVAHEEDGRRVFLD.SPASSDAIGRLCTR.GS.AGLVPF..SDRLAAEEWRSLRLAIKQETVAANIARCLTAFgeSPTA-----.--LVLAGGGALDDELMRTVGEALRSVP..IVVGRADVDGVHGPRFAVARGLIAMY..................................................................................................
B2TLK5_CLOBB/278-605                 ............................................................................................................................................VDVEHGAEKIMDAVNLCVPIQDVKGEAGTNAGGMLERVRQVMANLT.KQ..................KISDITIQDLLAVDTFIPQM.........VKGGLAAEFSMENAVGIAAMVKADKLQ...MQM.IAD..KLQE.QL......NVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GS.S.T.PLAILDMGAGSTDASIIN..KQGEI..C..S..I.H.L.A.G...A..G....N....M....VT....MLI......K..S......E..L....G......LE.D.....FSLAEDIK.K.HPLAKVESLFHIRHEDGTVEFFQ.KPLDSSVFAKVVIL.KD.GMLVPI..DGQNSLEKIRNIRKCAKEKVFVTNCLRALKIV..SPTGNIRDI.EFVVLVGGSSLDFEVPQVVTNALSQYG..VVAGRGNIRGSEGPRNAVATGLVLA-f.................................................................................................
Q8Y7W3_LISMO/275-602                 ............................................................................................................................................VNVAEGSEKIMQAIMSLPKLDNASGEPGTNIGGMLEKVRQTMAGLT.DK..................LPADIFIQDLLAVDTFVPVD.........VQGGLAGEFSMEQAVGIASMVKSDHLQ...MAA.IAS..EIEQ.EL......QVS.VKI..GG..A..EAEA.A.ILG..ALTTP.......GT.N.T.PLAILDLGAGSTDASIIN..GKGEI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......Q..S......E..I....G......LE.D.....RYLAEDIK.K.YPLAKVESIFHIRHEDGTVQFFD.TPLSPTVFAKVVIV.KP.DGFVPI..PGDVSIEKIKLIRRSAKERVFVTNTIRALKYV..SPTGNIRDI.PFVVIVGGSALDFEIPQLITDALSHYS..LVAGRGNIRGKEGPRNAVATGLILA-g.................................................................................................
A0A0R2LNX2_9LACO/276-603             ............................................................................................................................................VDVGTGADEIMQKISQIKDVQDIKGASGTNVGGMLENVRQTMAKLT.GR..................KIEQIYIQDLLAVDTSVPIK.........VRGGMANEFSMEEAVGIASMVKSDHLQ...MEL.IAK..SLQE.KL......NIP.VSI..GG..A..EAQS.A.IRG..ALTTP.......GT.D.K.PLALLDLGAGSTDASILS..QNGEE..V..A..I.H.L.A.G...A..G....D....M....VT....MII......D..S......E..L....G......LD.N.....AYLAEDIK.K.YPLAKVENLFQLRHEDGSVQFFE.KAISSDLFAKVVVI.KP.NGYEPL..PSKLNIEKVKAVRQSAKKRVFVTNALRALRYV..SPSGNIRDI.PFVVIVGGSALDFEIPQLVTDSLSQYN..IVAGRGNVRGIEGPRNAVATGLILRY..................................................................................................
A0A071LPX2_9ENTR/275-602             ............................................................................................................................................VDVAAGAEAIMQAVNSLPALDNVTGEAGSNIGGMLEHVRQTMAELT.NK..................PASEIAIQDVLAVDTAVPVS.........VTGGLAGEFALEQAVGIASMVKSDRLQ...MAR.IAR..EIEQ.TL......HVE.VQI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..GEGDI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......N..R......E..L....G......LD.D.....RNLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.SPLSPDVFARLCVV.KP.DELLPL..PGDHSLEKVRQIRRSAKQRVFVTNALRALERV..SPGGNIRNI.PFVVLVGGSALDFEVPQLITDALAHYR..LVAGRGNIRACEGPRNAVATGLILS-g.................................................................................................
A0A172USQ4_9MYCO/275-608             ............................................................................................................................................VDVSRGAVEIMAAVERVSPLVDVAGEAGTNTGGMIANVRQSMADLS.DH..................AVADVHIKDLLAVDTFVPQE.........VRGGVAGEVALENAVALAAMVRTRDSG...MQA.VAA..AVSE.RLrangaeGVE.VIV..GG..V..EAEM.A.VLG..ALTTP.......GT.D.K.PLVVLDLGGGSTDAALIE..TDGAI..A..A..V.H.L.A.G...A..G....D....L....VT....KLI......D..A......E..L....G......LD.N.....LELAEDIK.R.CPLGKAESFFHVRLENGTVQFFE.KPLPATAFARVVTL.DG.HSMNPI..PGRHSMERIATVRRTAKERIFVVNALRSLRTV..APGADLRQI.GFVVLLGGCALDFEIPQLIADALAPYG..IVCGTGNIRGIEGPRNAVASGLVSAY..................................................................................................
A0A0R2L312_9LACO/277-604             ............................................................................................................................................VGISDGADKIMKTVSSFKQIDNVTGESGTNIGGMLERVRQTMADLT.DK..................KMQDIFIQDLLAVDTSVPND.........VKGGLAGEFSMEQAVGIASMVRTDHLQ...MQM.IAD..EIQK.EF......DVK.VEV..GG..A..EAEA.A.IRG..ALTTP.......GT.Q.A.PLAILDLGAGSSDASIIN..KEGKI..V..A..I.H.L.A.G...A..G....D....M....TT....MII......N..S......E..L....G......LD.D.....VYLAEDIK.R.YPLAKVESLFYIRHEDGTVQFFD.DALPGNLFARTVVV.KP.DGFVPV..PGDVSIEKIRSVRQSAKQRVFVTNALRALAKV..SPTGNIRDI.PFVVIVGGSALDFEVPQLVTDALSHYN..LVAGRGNVRAIEGPRNAVATGLILAY..................................................................................................
A0A0R1HLP2_9LACO/279-606             ............................................................................................................................................VNVAGGAEAIMQKVNTFHAISDITGESGTNVGGMLEKVRQTMAELT.GK..................QNSEIAIQDLLAVNTSVPVK.........VQGGLAGEFSNEQAVGIAAMVKSDHLQ...MQR.IAD..LIKE.TL......DMP.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..RDNDI..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....VYLAEEIK.K.YPLAKVENLFQIRHEDGTVQFFD.KPLPAEIFAKVVVI.KP.EGYSPI..PGNLGIEQVKNVRQSAKKRVFVENARRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQFVTDELSHYS..LVAGRGNVRSVEGPRNAVATGLIISY..................................................................................................
C4S897_YERMO/275-602                 ............................................................................................................................................VDVATGSEAIMTAVNSFRHLDNVSGEAGTNIGGMLEHVRQTMAELT.NK..................PTNEIFIQDLLAVDTAVPVN.........VIGGLAGEFSLEQAVGIASMVKSDRLQ...MAH.IAS..EIEK.TL......GID.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.R.R.PLAILDLGAGSTDASIIN..AQGQI..V..A..T.H.L.A.G...A..G....D....M....VT....MII......A..S......E..L....D......LQ.D.....RYLAEDIK.K.YPLAKVESLFHLRHEDGSVQFFP.QPLSPEVFARLVVV.KP.EGLVPL..PGDYALEKVRNIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALSHYK..LVAGRGNIRASEGPRNAVATGLILAY..................................................................................................
K0UFG3_MYCVA/5-244                   ..................................................................................................................................rgtvavdslv----------------------------------------------.--..................--------------------.........----------------LAALGGADRTA...--A.DAD..ALAD.AL......GVP.VTR..ID..S..EAAA.A.RAG..AITTP.......GV.T.P.DVVVVDVGGGTVD--VVA..G-GSR..A..V..-.-.L.P.G...A..G....Q....L....LT....AAT......A..A......A..L....D......I-.S.....KSAAEYAK.R.AEALTAVTVQLVEDEHGRRRFLD.KAIPGRCTGWLLTS.AP.SGLLPF..TSRLTGSEWRSWRLAAKRLVIGGNVLRGIERV..APSA-----.SEVLLVGGGAGDDELVRAVSEQLGR-E..VTVGRGNVRGQLGHRFAVAYGLVA--la................................................................................................
A0A010YIW5_9ACTN/296-551             ..............................................................................................vavadlavvdvgalaksllvrigaggggyalaaldaaagpvpadal----------------------------------------------.--..................--------------------.........---------------------------...---.---..-LTE.AL......GVP.VVS..AS..S..EAAA.A.RSG..ALTTP.......GA.P.A.DAVVVDIGGGTVD--VIG..PAHER..V..L..-.-.-.A.G...G..G....D....L....LT....AAV......A..L......G..L....D......V-.T.....RGAAEWAK.R.GPAVRVETPQLATQEDGDKTFLE.APQPAGTVGWLAAP.GP.AGLLPI..TVRIGPAEWRTFRLALKQAVLGTAVRRGLVG-..-AG------.-TVLVVGGPAGDDEVLRVV-DAVLPPG..AGLGRGNVAGVLGHRYAVAWGLALA-a.................................................................................................
A0A089PLR2_PLUGE/277-604             ...........................................................................................................................................a-DVARGADGIMQAMAGCAPVQDIRGEAGTHAGGMLERVRSVMATLS.GH..................AMSDIRIQDLLAVDTFIPRK.........VQGGIAGEFSMENAVGIAAMVKSDRLQ...MQA.IAS..ALSE.RL......HTE.VVV..GG..V..EANM.A.VAG..ALTTP.......GC.A.A.PLAILDLGAGSTDAAIIS..AEGSV..K..S..V.H.L.A.G...A..G....N....M....VS....LLI......K..T......E..L....G......LS.E.....LHLAEELK.K.YPLAKVESLFSIRHENGAVEFFR.EPLSPSVFAKVVYI.KD.GELIPV..DNLTSLEKIRTVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEVPQLITDALSHYG..VVAGQGNIRGTEGPRNAVATGLVLA-c.................................................................................................
I9LEU7_9FIRM/275-602                 ............................................................................................................................................IDVESGAGKIMETVERVQPVLDVQGEAGTHVSGMLERVRQVMSELT.KQ..................HLGDMKIQDILAVDTFVPQK.........VQGGLAGEFALENAVALAAMVKTSRLP...MEQ.IAN..QLRS.NL......GVD.VVI..AG..V..EANM.A.IRG..ALTTP.......GT.D.K.PLAILDMGGGSTDAAIIT..RDERV..L..S..I.H.L.A.G...A..G....D....M....VT....MLI......N..S......E..L....G......LN.D.....FDLAEDIK.K.YPLAKVESLYHIRLEDGTVRFYE.QHLPPQVFSRVVIL.KD.GEMVPI..PSSHPLDKIRHVRREAKKRVFVTNAIRSLSRV..APTGNIRHI.EFVVLVGGSAMDFEVGDMVTDALAEYS..IVCGRGNIRGSEGSRNAVATGLVLSY..................................................................................................
A0A0R2B4T5_LACCL/278-605             ............................................................................................................................................VGVSEGAAAIMKKISQFRHIEDITGESGTNIGGMLEKVRQTMATLT.GK..................QNKDVAIQDLLAIDTQVPVK.........VKGGLAGEFSNESAVGIAAMVKSDRLQ...MEV.IAK..LIEK.EL......NTK.VEI..GG..A..EVES.A.IRG..ALTTP.......GT.S.K.PIAILDFGAGSTDASIIN..KEDQT..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LS.D.....VHLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KPLPSELFARVVVI.KP.EGYEPV..TGNPSIEKIKLIRQSAKKRVFVTNAIRALKYV..SPTGSIRDI.PFVVIVGGSALDFEIPQLVTDQLAHYN..LVSGRGNVRGIMGPRNAVATGLVLRY..................................................................................................
C6JP61_FUSVA/274-601                 ............................................................................................................................................IEVDKGAEPIMEALEACFPINDIWGETGTNAGGMLEKVRIVMAQLT.DQ..................DPKDIKIQDLLAVNTFVPKK.........VKGGIAEEFSMENAIGLAAMVKADRLQ...MER.IAL..DLQE.KL......GKS.VVV..GG..V..EAEM.A.IIG..ALTTP.......GT.N.K.PLAIIDMGAGSTDASVIT..REGRI..S..S..C.H.L.A.G...A..G....N....M....VT....MLI......D..K......E..L....G......LD.N.....FDLAEDIK.K.YPLAKVESLFHIRHEDGSVEFFE.DTLDPRTFARVVIL.KE.GKMIPL..DIDEPIEKIKKVRRDAKEKVFVVNAVRALKKV..SPSGNIRDI.DHVVLVGGSALDFEVPQMVTDKLSYYG..VVAGRGNIRGTEGPRNAVATGLALSY..................................................................................................
W9ATZ9_9MYCO/274-579                 ...........................................................................................................................................v-DCRIAGQTVRFAPEQAYPL--LRAEAPGTAVRV--RLRSLKSAED.GI..................AVDDAYFTDLAAIDDGAWLR.........--RGVAETRG----AVVA-LLAADH--...VAD.AAE..TMTE.LT......GRP.AQT..LA..A..EPAA.A.ASG..ALTTP.......GL.P.A.DVVVCDIGGGTVD--LIG..PDRTV..T..A..-.-.-.A.G...A..G....E....T....IT....SAV......A..R......V..L....N......I-.P.....RALAERVK.R.SPALRVEGPHLAHEEDGRRVFLD.TPATADAIGRLCTR.GS.AGLVPF..SRTLAAEEWRSLRLAVKEATVASNIVRCLKVF..ERMP-----.AVLVLAGGGALDDELIRTVGEALRAAGsaTVVGRANIDGIHGPRYAVASGLVH--la................................................................................................
A0A017T542_9DELT/6-49                .....................................................................................................................................aptaasf----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.--V..AY..S..EADM.A.LRG..ALTTP.......GT.A.R.PLAILDLGGGSVAA----..-----..-..-..-.-.-.-.-...-..-....-....-....--....---......-..-......-..-....-......--.-.....--------.-.-----------------------.--------------.--.------..--------------------------------..---------.---------------------------..--------------------------fh................................................................................................
A6TDD5_KLEP7/275-602                 ............................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVAGEAGTNIGGMLEHVRQTMAELT.NK..................PAQEIRIQDLLAVDTAVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAL.IAR..EIEH.KL......QIA.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..AQGEI..S..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.SALPPAVFARVCVV.KP.DELVPL..PGDLPLEKVRAIRRSAKSRVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYR..LVAGRGNIRGCEGPRNAVASGLLLSW..................................................................................................
U2QEV7_9ACTN/273-600                 ............................................................................................................................................VDVEAGAEEIMRAAARAGLLRDVRGEPGTNIGGMMEKVRVTMARLT.GR..................EPSDIEITDLLAVDTQVPQS.........VTGGLAGEFSLEAAVGMAVMVKADRLQ...MQR.IAE..EMTG.QF......GIR.VEI..GG..V..EADM.A.IRG..ALTTP.......GT.S.L.PIAILDMGAGSTDASVLR..EGDEA..V..S..I.H.L.A.G...A..G....D....M....VT....MLI......A..S......E..L....G......LE.G.....TDLAERIK.R.HPLARVETLFNIRHEDGTVQFFD.EPLAPELYARTVVL.DA.EGMLPL..PLRQPLEAIRRIRIRAKERVFVTNALRALAAV..SPTRNVRDI.AHVVLVGGSALDFEIPQLVTRALGEYR..VVAGRANIRGTEGPRNAVATGLVLS-r.................................................................................................
S0J4Q5_9FIRM/274-601                 ............................................................................................................................................VDVDAGGEKIMQAVESLPALEDVRGEPGTNAGGMLEKVRQVMANLT.KQ..................HPKDIHIQDLLAVDTFTPQK.........VQGGLANEFSQENAVGIAAMVKADRLQ...MEA.IAR..EFSE.QI......NIP.VKV..GG..V..EADM.A.IRG..ALTTP.......GT.N.K.PLAILDMGAGSTDASIIN..REGEI..H..S..I.H.L.A.G...A..G....N....M....VT....LLI......Q..S......E..M....G......LD.S.....FDTAEDVK.K.YPLAKVESFFHIRHENGTVEFFT.EPLSPDIFARTIIL.KE.GKMIPL..EGDWSMEKIRLIRRQAKQKVFVTNALRALARV..SPTGNVRDI.QFVVLVGGSALDFEVPQMVTDALSQYK..VVAGRGNIRGTEGPRNAVATGLVLS-l.................................................................................................
W9BLL4_9MYCO/272-605                 ............................................................................................................................................VDVSRGAVEVMAEVERVSPLMDVTGQAGTNSGGMIANVRQSMADLS.NH..................TLADVHIQDLLAIDTLVPKE.........VRGGVAGEVALENAVALAAMVRTKESG...MQA.VAD..EVAA.QLrglgaeAVE.VVV..GG..V..EAEM.A.VLG..ALTTP.......GT.D.K.PLVVLDLGGGSSDAAVIQ..TDGRT..E..A..T.H.L.A.G...A..G....D....L....VT....KLI......D..A......E..L....G......LD.N.....LELAEQIK.R.CPLGKAESFFHVRLENGTVQFFD.TPLPATAFARVVTL.GD.TGMSPI..PTRHSLDRIRGVRRTAKERVFVVNALRALRGI..APGGDLRQI.GFVVLLGGCALDFEIPQLIADAVAPYG..IVCGTGNVRGTEGPRNAVASGLVAA-f.................................................................................................
A0A0T1WE25_9MYCO/260-563             ............................................................................................................................................VDCTVDGEVVRYSPAQAHVV--LRLAPPGNVVEV--RLKSVRSARD.GL..................AVDDAFFTDLSSIDNGAWLR.........--RGVADTRGTVVALLAADLV------...-AD.AAS..TLQE.LT......GRP.TRT..VA..G..EPEA.A.AVG..ARTTP.......GL.P.P.GTVVCDIGGGTID--LIG..DDREV..T..A..-.-.-.A.G...A..G....E....A....IT....TAV......A..R......V..L....G......I-.P.....RALAERVK.R.TPALRVEGPHVAHEEDGRRLFLD.SPAPADAIGRLCTR.GS.AGLVPF..SNKLAAEEWRSLRLAVKQETVAANIVRCLRAF.dAPPP-----.-ALVLAGGGALDDELLRTVAEALRSAS..IVVGRANVDAQHGPRFAVASGLVHLY..................................................................................................
I4BU32_ANAMD/277-605                 ............................................................................................................................................INIDEGAKAIMEMVESSWPIQDIFGQPGTNVGGMMERVRKTMSELT.SL..................PLGEIHIKDLLAVDTMVPQR.........VVGGLAEEFAMENGVALAVMVEAQELP...MQR.LAS..AIES.EI......GVK.AEI..GG..V..EAEM.A.IMG..ALTTP.......GT.S.T.PLAVLDLGAGSTDASLMR..PNGQV..E..L..I.H.L.A.G...A..G....N....M....VN....TII......A..S......E..L....G......LD.D.....MELVENIK.M.HPLCKVESVFHVRLEDGTVRFFD.KPLAPELFGRVALIiSE.DFLSPI..LLDASIEKIRDVRRKAKREVFVTNATRALKRV..APAQNIRLI.DFVVLVGGSALDFEIPNMITEELSKYS..VVAGRGNIRGTLGPRNAVATGLVLS-t.................................................................................................
A5VMA9_LACRD/278-605                 ............................................................................................................................................VGVSEGADAIMKKVSSFRHINNITGESGTNVGGMLENVRQTMADLT.GK..................KNDEIAIQDLLAVDTQVPVE.........VRGGLAGEFSNESAVGIAAMVKSDHLQ...MEV.IAK..LIEK.EF......NTK.VEI..GG..A..EVES.A.IRG..ALTTP.......GT.D.K.PIAILDLGAGSTDASIIN..KENNT..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LN.D.....IHLAEDIK.R.YPLAKVENLFQIRHEDGSVQFFK.DPLPSSLFAKVVVI.KP.DGYEPV..TGNPSIEKIKLVRQSAKKRVFVTNALRALKYV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELAHFN..LVAGRGNVRGVEGPRNAVATGLILRY..................................................................................................
A0R5U9_MYCS2/262-565                 ............................................................................................................................................VEFARDGEQVRYPPAQAHTI--LRREPPGSVVRI--RLRSVPTADH.EM..................AVDDAFFTDLAALDNGTWLRrgvadasgtVVALLAADHVADAAATLAELT------...---.---..----.--......GRP.ART..LA..S..EPEA.A.ARG..ARTTP.......GL.P.P.DSVVCDIGGGTID--LVG..AERTV..T..A..-.-.-.A.G...A..G....E....T....IT....VAV......A..K......M..L....G......I-.P.....RALAERVK.R.TPAIRVEGPHVAHEEDGRRLFLD.APAPAEAIGRLCTR.GT.AGLVPF..SSRLAAEEWRSLRLAIKQETVAANIARCMKAFekPPTA-----.--LVLAGGGALDDELLRTVGESLRTAG..VVVGRANIDGVHGPRFAVASGLVHLY..................................................................................................
A0A0T1W7J9_9MYCO/279-612             ............................................................................................................................................VDVSRGAADIMAEVQRVSPLVDVMGEAGTNTGGMIANVRQSMADLS.NH..................ALADVRIGDLLAIDTAVPQE.........VRGGMAGEVALENAVALAAMVRTKESG...MKA.VAE..AVTS.HLraagatKVD.VAV..GG..V..EAEM.A.VLG..ALTTP.......GT.D.K.PLVVLDLGGGSTDAAVIE..TDDHT..D..A..T.H.L.A.G...A..G....D....L....VT....KLI......D..A......E..L....G......LD.N.....LELAEEIK.R.CPLGKAESFFHIRLENGTVQFFE.KPLPPTAFARVVAL.GE.TGMNPI..PTRHSLDRIRAVRRTAKERVFVVNALRALRSI..APGGDLRQI.GFVVLLGGCALDFEIPELIADAVAPFG..IVCGTGNVRGTEGPRNAVASGLVASY..................................................................................................
R5BN42_9FIRM/275-602                 ............................................................................................................................................IDISAGAEQIMATLGQVSHIDNVCGEAGTNVGGMLERVRQTMADLT.NK..................SPNDVFIEDLLAVDTSVPIN.........VKGGLAGEFSMEQAVGIASMVKSDHLQ...MEI.IAK..EVER.EL......KIP.VEI..GG..Q..EAES.A.ILG..ALTTP.......GT.E.T.PLAILDLGAGSTDASIMS..PDGRV..T..A..I.H.L.A.G...A..G....N....M....VT....MLI......N..S......E..L....G......LE.D.....IHLAESIK.K.FPLAKVISVYHIRHEDGNVQFFK.DPLPADLFAKTVIV.TD.EGLVPI..EGDQSMEKIKIVRQTAKERVFVTNSLRALRAV..SPTHNVRDI.PFVVIVGGSALDFEVPQLVTDALSHYN..LVAGRGNVRGTEGARNAVATGLILSY..................................................................................................
A0A132T3J4_9MYCO/277-593             ............................................................................................................................................VDVSLGAADIMAEVERVGPLVDVAGESGTNAGGMIANVRQSMADLS.KH..................DIGDVKITDLLAIDTQVPQE.........VRGGVAGEVALENAVALAAMVRTKESG...MQA.VAD..AIAE.RLriagaeRVA.ALV..GG..V..EAEM.A.VRG..ALTTP.......GT.D.R.PLVVLDMGGGSTDAAVIG..TDGAI..D..A..V.H.L.A.G...A..G....D....L....VT....KLI......D..T......E..L....G......LG.N.....LELAEEIK.R.CPLGKAESFFHVRLENGTAQFFE.KPLPATAFARVVTL.SG.QAMNPI..PTRHSIDRIREVRRTAKQRVFVVNALRALRSI..APAGDLRRI.GFVVLLGGCALDFEIPELIADALAPYG..IVCGTGNVR-----------------..................................................................................................
D2Z8G8_9BACT/278-606                 ............................................................................................................................................VDVEAGAEAIMNLLSVCHPITDIFGQPGTNVGGMMERVRTTMAKLT.GL..................SIAEIHIQDLLAVDTMVPQK.........VVGGLAGEFSQENGVALAVMVKTAKLP...MQA.VAE..AVSE.DI......GIK.VEI..GG..V..EADM.A.IRG..ALTTP.......GT.D.R.PIAILDLGAGSSDASFMK..YDGSV..E..L..I.H.L.A.G...A..G....N....M....VN....TVI......C..S......E..L....G......IE.D.....PELAESIK.R.YPLCKVESAYHVRQEDGTVRFFD.RPLAPDLFGRVALA.ISdDILQPI..PLRVSMEKVRMVRRKAKKEVFVTNALRALEHV..APAGNVRMI.DHVVLVGGSAKDFEIPTMVTDALARYG..VVSGRGNVRGSEGPRNAVATGLVLSY..................................................................................................
A0A172UJQ0_9MYCO/269-514             ...............................................................................................................aqansrrgsvtadslvmaamgaaggapad----------------------------------------------.--..................--------------------.........---------------------------...---.-AD..ALAD.AL......GVP.VTR..IE..S..EADA.A.RAG..ALTTP.......GI.P.A.GVVVVDVGGGTVD--VVA..ADGRA..V..L..-.-.-.P.G...A..G....Q....L....LT....VAT......A..T......A..L....D......I-.S.....ISAAEYAK.R.AEAVTAVTVQLVEDEHGRRRFLD.APIDGRCTGWLLTA.AP.SGLLPF..TSALSGAEWRSWRLAAKRLVIGGNVTRGVQQV..ASGA-----.TGVLLVGGGAGDDELVRALTEQLGR-D..VTVGRGNVAGGLGHRFAVAYGLVV--la................................................................................................
E3CVA2_9BACT/277-605                 ............................................................................................................................................VNVEDGAEAIQTTVAASAPVENIFGQPGTHVGGMMERVRRTMSDLT.GI..................PLGEVSIRDLLAVDTLVPQK.........VVGGVAGEFSLESGVALAVMVKTEELP...MQR.LAE..AVSA.DL......GVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.K.R.PLAVLDLGAGSSDASFMK..EDGTV..D..L..V.H.L.A.G...A..G....N....M....VN....TIL......A..S......E..L....G......IE.D.....PDLAESIK.R.YPLCKAESAFHIRQEDGTVRFFD.APLDPQVFGRVALL.HEnDLLQPI..PLPVTLEKVRAARRKAKKEVFVTNALRALEQV..APAGNVRML.DHVVLVGGSASDFEVPTLITEALSRYG..IVAGRGNIRGKEGPRNAVATGLVLS-a.................................................................................................
A9MLQ0_SALAR/275-602                 ............................................................................................................................................IDVAAGADAIMKAVSNCPQLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSAEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAR..EIEQ.KL......SID.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..PKGEI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LN.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.APLPPEVFARVCVV.KP.DELVPL..PGDIALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSALDFEVPQLVTDALAHYR..LVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
Q8XLV8_CLOPE/280-607                 ............................................................................................................................................VDVEEGADKIMEAVSLCSPIEDLRGDAGSNVGGMLEKVRQVMADLT.NQ..................SISDIKIQDLLAVDTFIPQK.........VKGGLAKEFSMENAVGIAAMVKAHKLQ...MQI.IAN..KLEE.KL......GVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.N.T.PLAILDMGAGSTDASIIN..KEGKI..T..S..I.H.L.A.G...A..G....N....M....VT....MLI......K..S......E..L....G......IE.D.....FGLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.KPLDSSVFAKIVII.KE.GMLIPV..DGQNSLEKIKNVRKTAKERVFVINCLRALKSV..SPTGNIRDI.EFVVLVGGSSLDFEVPELVTDALSHYG..VVAGRGNIRGCEGPRNAVATGLVLA-f.................................................................................................
G9YVN8_9FIRM/274-601                 ............................................................................................................................................VDVDDGADKIMKAVESIPSLEDVRGEPGTNAGGMLEKVRQVMANLT.SQ..................HPRDIKIQDLLAVDTFTPQK.........VQGGLANEFSQENAVGIAAMVKADRLQ...MEA.IAR..EFAQ.QI......GVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.N.K.PLAILDMGAGSTDASIIN..AEGQI..H..S..I.H.L.A.G...A..G....N....M....VT....LLI......Q..S......E..M....G......LP.D.....FDTAEDVK.K.YPLAKVESLFHIRHENGTVEFFQ.QPLDPNLFAKVVIL.KE.GKLLPL..EGDWSMEKIRLIRQQAKQKVFVTNAIRALTRV..SPTGNVRDI.QFVVLVGGSALDFEVPQMVTDALSQYK..VVAGRGNIRGTEGPRNAVATGLVLS-l.................................................................................................
V5X9M2_MYCNE/272-605                 ............................................................................................................................................IDVSRGAAEIMAEVERVSPLQDVLGESGTNTGGMIANVRQSMADLS.KH..................ALADVRIKDLLAIDTLVPQE.........VRGGVAGEVALENAVALAAMVRTKESG...MQA.VAD..AVAT.ALrdagatRIS.AVV..GG..V..EAEM.A.VLG..ALTTP.......GT.E.K.PLVVLDMGGGSTDAAVIE..RSGDV..Q..A..V.H.L.A.G...A..G....D....L....VT....KLI......D..A......E..L....G......LD.N.....LELAEDIK.R.LPLGKAESFFHVRLENGTVQFFD.KPLPPNAFARVVTL.SE.MGMSPI..PTRHSLDRIRTVRRTAKERVFVVNALRALRAV..APHGDLRQI.GFVVLLGGCALDFEIPELIADAVAPYG..IVCGTGNVRGTEGPRNAVASGLVASY..................................................................................................
R6G9W5_9FIRM/273-601                 ............................................................................................................................................VDVDEGADKIMEAISSIQEIDDIQGETGTNVGNMLNKVRRVMAGLT.NK..................SPQDIKIQDLLAVDTFNPQK.........VVGGIADEFALENAVGIAAMVKSDRLQ...MEM.IAQ..VLTE.KL......RVP.VYV..GG..V..EADM.A.IKG..ALTTP.......GT.S.V.PLAIVDMGAGSTDASIIN..REGKV..K..L..I.H.L.A.G...A..G....N....M....VS....LLI......Q..S......E..L....G......LD.D.....FELAEDVK.K.YTLAKVESLFHIRHENGTVQFFD.KPLDPSIFAKVVLV.KEnDELVPL..DGVESLEKVKAVRMEAKKKVFVTNAIRSLSKV..SPTGNPRDI.QFVVMVGGSALDFEIPNFVTDALADYE..IVAGRGNIRGCEGPRNAVATGLAMA-c.................................................................................................
A0A0H3J8Q7_CLOPA/275-602             ............................................................................................................................................VDVEDGASKIMEVVKSTVSIEDIKGESGTNVGGMFERVRQVMSKLT.NQ..................DFQSIKIQDILAVDTFVPQK.........IVGGLAREFSLENAVGIAAMVKADKLQ...MQI.IAD..ELKN.KL......SVE.VEI..GG..V..EAEM.A.ILG..ALTTP.......GS.N.K.PLAILDMGAGSTDASIIN..KNGEI..S..S..V.H.L.A.G...A..G....N....M....VT....MLI......N..S......E..L....G......LN.S.....FDLAEDIK.R.YPLAKVESLFHIRHEDGTVEFFE.EHFDPSIFARTVIL.KE.GNLIPI..NIEASIEKIKMIRKMAKEKVFVTNCIRALSIV..SPTGSIRDI.EFVVLVGGSSLDFQVPQLITDALSKYG..VVAGRGNIRGLEGPRNAVATGLILD-i.................................................................................................
R5RU48_9FIRM/273-600                 ............................................................................................................................................VSIDAGGVKIMKSLQKAGDILDIVGQPETNVGNMFHNIRENMAKVS.GE..................TKEKIRITDLLAVDTMAPVE.........ISGSLAGETCMEKAVGIAAMVKTHHLP...MEQ.IAE..KLEE.EL......HLK.GKV..AG..V..EAVM.A.SLG..ALTTP.......GT.Q.L.PLAILDMGGGSTDAALLD..ADGTV..K..T..T.H.Q.A.G...A..G....E....L....VS....MLI......Q..T......E..L....G......FK.S.....RATAEQIK.K.YPLAKVESLFHMRLENGAMEFFQ.DSIDPRYYGHVVLL.AP.GELLKI..EEDIPMERIRQVRREAKEKVFVTNALRALEKV..APEHNLKNI.SNVVLVGGSAEDFEIPEMLTQILAEYR..IVCGRGNIRGQEGPRNAVATGLLLS-s.................................................................................................
A0A0T9XBB3_SALET/1-162               ............................................................................................................................................----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPTVFARVCVV.KP.DELVPL..PGDLALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYR..LVAGRGNIRGSEGPRNAVATGLILSW..................................................................................................
E3H9G3_ILYPC/274-601                 ............................................................................................................................................VNIEEGSKRIMKALGSIEHVQDINGESGTNIGGMLKNVKSVMGNFT.NE..................SIDNIKIKDILAVDTFVPQK.........IKGGIAEEFVFENAVGIAAMVNTKKNQ...MSE.VAK..EIEK.EL......GVK.VEV..GG..V..EADM.A.ITG..ALTTP.......GT.G.T.PLVIVDIGAGSTDACSID..RYGNK..E..L..V.H.L.A.G...A..G....N....M....TT....LLI......Q..K......E..L....G......IE.D.....FNLAEDIK.K.YPLAKVESLFYIRHEDGNVQFFE.NSLSPKVFAKNVLI.KE.GELIPI..DLDMSLEKIRIIRRSAKRKIFITNVLRSLRKV..SHTKNIRDF.EFVVIVGGSALDFEISQMITEALSEYG..IVAGCGNIRGTEGPRNAVATGLVM--gv................................................................................................
I3VRW4_THESW/275-603                 ............................................................................................................................................VSVDSGAEAIMESVEEVGTIDDVEGEENTNVGNMIKNLKNKMANIT.GQ..................KVDKIKIKDIFAVDTTVPVK.........VEGGLAGETSMEKAVVLAAMVKTDTLP...MIE.IAE..KLQR.KL......GVF.VKI..AG..V..EAVM.A.TLG..ALTTP.......GT.K.L.PLAILDIGGGSTDAALID..EKGIV..K..S..I.H.M.A.G...A..G....E....L....VT....MLI......D..S......E..L....G......LN.D.....RYLSEEIK.R.NPIGKVESLFHIRMENREIKFFD.KPLNPRYYGRIVIL.KE.NDMIPV.fKEDLTMEKIIYVRRQAKDKVFVKNAIRALKKI..APENNLRRI.PNVVLVGGSALDFEIPEMILSELSKYK..IIAGRGNIRKIEGPRNAVATGLVMSY..................................................................................................
F0Z327_9CLOT/273-600                 ............................................................................................................................................VNLDEGAEKIMQAVSDAGSIRDISGQPNTNVGNMLSRIKQGMGELD.NT..................PDADIHITDVLAVDTLAPVL.........ISGALAGETCLEKAVGIAAMVKTRQLP...MRE.IAE..KLKL.EL......GTD.VKV..AG..V..EAVM.A.SLG..ALTTP.......GT.Q.L.PLAILDMGGGSTDAAVIS..EEGQV..T..M..T.H.Q.A.G...A..G....E....L....VS....MLI......E..T......E..L....G......LG.D.....RHMAEQIK.K.YPLAKVESLFHMRMENGQMTFVE.DSIDPRFYGRVILL.AE.DGFIRM..EKDIPMEKIVQVRRDAKRKVFVTNAFRALKKV..APGHDLRNI.SNVVLVGGSAEDFEIPEMLMEEFAGYR..IVCGRGNIRGAEGPRNAVATGLVLSY..................................................................................................
A0A0R1S1M4_9LACO/276-603             ............................................................................................................................................VNVAAGANAIMKKVNEFNNIDDITGESGTNVGGMLEKVRQTMADLT.DK..................QNKDIAIQDLLAVNTSVPVK.........VKGGLAGEFSMEQAVGIAAMVKSDHLQ...MQL.IAN..LIQD.QM......HVP.VEI..GG..A..EAES.A.ILG..ALTTP.......GT.T.K.PLAILDLGAGSTDASIIN..KKDER..V..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....IYLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KPLPAKLFARVVVI.KP.DGYEPI..PGNLGIEKVKIVRQTAKKRVFVTNATRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRAIEGPRNAVATGLILSY..................................................................................................
A0A0T7RPS8_SALET/3-38                ........................................................................................................................................plsi----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....-....--....---......-..-......-..-....-......--.-.....--------.-.-----------------------.--------------.--.------..--------------------------------..---------.---------------------TMAQYG..VVAGQGNIRGTEGPRNAVATGLVLA-g.................................................................................................
A0A0R2D0U7_9LACO/277-604             ............................................................................................................................................IGISDGAEKIMQVISSFDTIDDVTGEAGTNIGGMLERVRQTMAELT.DK..................KLTDIAIQDLLAINTSVPIN.........VRGGLAGEFSMEQAVGIASMVKSDRLQ...MSR.IAK..AIEE.EM......KVK.VDI..GG..A..EAEA.A.IMG..ALTTP.......GT.S.K.PVALLDLGAGSTDASIIN..QQDKI..M..A..I.H.L.A.G...A..G....D....M....VT....MII......N..S......E..L....G......LD.D.....LYLAEDIK.R.YPLAKVENLFQLRHEDGSVQFFE.KALPADIFAKTVVV.KP.TGYEPV..PGDLSIEKIRLVRQTAKKRVFVTNAIRALKHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDALSHYN..LVAGRGNVRSIEGPRNAVATGLILRY..................................................................................................
A0A0X8D3V8_9BACL/223-338             ............................................................................................................................................VSINDGADIIMQGMERAGQLLDAVGEAGTNVGGMLNGLRQNLADAT.GQ..................PFDAITIGDLLAVDAMIPVS.........VSGAIAGELSMESGVAIASMVKTGRVP...VQK.VAQ..AAVK.AF......E--.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....-....--....---......-..-......-..-....-......--.-.....--------.-.-----------------------.--------------.--.------..--------------------------------..---------.---------------------------..--------------------------kmatqvka..........................................................................................
G8PEJ6_PEDCP/276-603                 ............................................................................................................................................VNVATGATEIMKHINNFDQITDISGEAGTNVGGMLEKVRQTMAELT.GK..................QNKDIAIQDLLAVDTSVPVR.........VQGGLAGEFSTEQAVGIAAMVKSDHLQ...MQR.IAD..LIQS.EL......HID.VEI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.K.PIAILDLGAGSTDASIIN..QKDEI..V..A..I.H.L.A.G...A..G....D....M....TT....MII......N..S......E..L....G......LN.D.....VYLAEDIK.K.YPLAKVENLFQIRHEDGTVQFFD.QPLPSEIFARVVVI.KE.DGYIPV..PGNMSIEKIKTVRQTAKKRVFVENARRALQHV..SPTGNIRDI.PFVVIVGGSALDFEIPQLVTDELSHYN..LVAGRGNIRSVEGPRNAVATGLILSY..................................................................................................
A0A0D1VHX9_ANEMI/276-603             ............................................................................................................................................VAINDGAEEIMRSIERAGGLINVQGEMGTNVGGMLNGLRQYLSEST.GQ..................PFADISIGDLLATDVLIPVS.........VSGAMAGELSMESGVALASMVKTERMP...VER.VAQ..ALEK.EL......GIP.VEV..GG..V..EAEM.A.IRG..ALTTP.......GT.E.K.PLVILDMGGGSTDAAAVS..EGGET..I..S..V.H.L.A.G...A..G....D....M....VT....MLI......D..A......E..L....A......LH.S.....RELAEKVK.K.NPLGKVMSLFHMQLEDGTMLFSE.SPFPPDVYGRVVIR.EE.KELVPL..PVKLSMEKVRAVRRSAKRRVFVTNAIRALAYI..VPTKNIRHL.SFVVMVGGSALDFEIPQMVTEELGKYG..IVAGFANVRGTEGPRNAVATGLVLS-v.................................................................................................
C4LFD2_TOLAT/275-602                 ............................................................................................................................................VDVASGSEKIMQAVKACRQLDNVTGESGSNIGGMLENVRQTMAELT.NK..................PSGEIFIQDLLAVDTFVPVN.........VQGGLAGEFSLEQAVGIASMVKSDHLQ...MAR.IAE..EIHN.TL......HIG.VQI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.K.PMAILDLGAGSTDASIIN..PQGEI..V..A..T.H.L.A.G...A..G....D....M....VT....MII......A..S......E..L....G......LE.D.....RYLAEDIK.K.YPLAKVESLFHIRHEDGSVQFFD.SPLPAAVFARVVVV.KE.GKFIPL..PGEFALEKVRNIRRSAKERVFVANSLRALQFV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALSHYN..LVAGRGNIRGCEGPRNAVATGLILSY..................................................................................................
S2WWZ2_9ACTN/274-601                 ............................................................................................................................................VDVDNGAEKIMAALGEVTDVTDITGEPGTNVGGMMEQVRVSMGTLT.DQ..................NPKDIKITDLLAIDTRTPKQ.........VAGGIANEFSMEAAVGIAVMVHADRLQ...MQM.IAD..EISA.EI......GIP.VEV..GG..V..EADM.A.IQG..ALTTP.......GV.A.A.PIAVLDMGAGSTDASVMH..ADGSI..V..S..T.H.L.A.G...A..G....N....M....VT....LMI......K..T......E..L....G......LS.D.....THIAEDIK.R.YPLAKVETIFSIRHEDGTVQFFN.DPLPPETFARVVIM.KP.DGLVPL..DIDLPVETIRQVRIRAKQQVFVTNAVRALRKV..SPTENVRDI.DFVVLVGGSALDFEIPQLVTHALADYR..VVAGRANIRGSEGPRNAVATGLALSW..................................................................................................
O31043_SALTY/275-602                 ............................................................................................................................................VDVAAGAEAIMKAVDGCGKLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSSEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAR..EIEQ.KL......NID.VQI..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..PKGEI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPAVFARVCVV.KP.DELVPL..PGDLALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYR..LVAGRGNIRGSEGPRNAVATGLILSW..................................................................................................
A8AEN2_CITK8/275-602                 ............................................................................................................................................VDVAAGAEAIMKAVGECRKLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSNEIFIQDLLAVDTSVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAR..EIKQ.KL......SVD.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.R.PLAILDLGAGSTDASIIN..PKGEI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LD.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.TPLPPAVFARVCVV.KP.DELVPL..PGDLALEKVRAIRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEIPQLVTDALAHYR..LVAGRGNIRGTEGPRNAVATGLILSW..................................................................................................
X5KSI9_9MYCO/259-562                 ............................................................................................................................................IEFRIDAEVVRYAPAQAHGI--LRSQPPGTVARI--RLRSIPTADH.EM..................AVDDAFFTELSALDNGAWLR.........--RGVADARGT-----VVALLAADH--...VAD.AAE..TLGR.LT......GRP.ART..IA..T..EPAA.A.ARG..AQTTP.......GL.P.P.DTVVCDIGGGTID--LIG..PDRAV..T..A..-.-.-.A.G...A..G....E....T....IT....VAV......A..R......M..L....N......I-.P.....RALAERVK.R.TPAIRVEGPHVAHEEDGRRLFLD.GPAPADAIGRLCTR.GS.AGLVPF..SNKLAAEEWRSLRLAIKQETVAANIARCLKAFekPPTA-----.--LVLAGGGALDDELLRTVGESLRTVP..VVVGRANIDGVHGPRFAVAAGLVH--la................................................................................................
A0A076N3Z9_AMYME/275-601             ............................................................................................................................................VEIDAGAAEIMATLRRVRPLTDATGEAGTHVGGMLARVRDTMSELT.GT..................AVGAVRIQDVLAVDTFVPQE.........VTGALAGEFALENAVALAAMVRTSRGP...MRL.LAE..KLRE.AL......GVE.VLI..GG..V..EADM.A.VLG..ALTTP.......GT.G.R.PVAILDLGGGSTDAA-VA..GDGVV..R..S..V.H.L.A.G...A..G....D....L....VT....KLI......D..S......E..L....G......LD.N.....RELAEDIK.K.YPLAKAESFFHVRMEDGTARFFD.EPLPVEAFARVVVL.SE.AGMRPV..PTRHNLEKIRQVRRSAKHKVFVVNALRALEQV..APGGNLRQI.GFVVVLGGSALDFEIPDMIAEAVAGMG..IVCGTGNVRGSEGPRNAVATGLVAS-h.................................................................................................
R6EEW3_9FIRM/1-159                   ............................................................................................................................................----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....-....--....MLT......E..T......D..L....G......RG.A.....RHMAEQIK.K.YPLAKVESLFHMRMENGQMTFVE.DSIDPRFYGRVVLL.AE.DGLIRI..EQDIPMEKIAAVRREAKRKVFVTNAFRALKKV..APGHDLRKI.SNVVLVGGSAEDFEIPEMLMEEFAGYR..IVCGRGNVRGSEGPRNAVATGLVLSY..................................................................................................
D2TPR1_CITRI/275-602                 ............................................................................................................................................VDVAAGADAIMKAVGDCPKLDNVTGEAGTNIGGMLEHVRQTMAELT.NK..................PSNEIFIQDLLAVDTAVPVS.........VTGGLAGEFSLEQAVGIASMVKSDRLQ...MAM.IAS..EIKE.KL......NVD.VQV..GG..A..EAEA.A.ILG..ALTTP.......GT.T.C.PLAILDLGAGSTDASIIN..PQGDI..I..A..T.H.L.A.G...A..G....D....M....VT....MII......A..R......E..L....G......LE.D.....RYLAEEIK.K.YPLAKVESLFHLRHEDGSVQFFP.GPLPPTVFARVCVV.KP.DELVPL..PGDLPLEKVRAVRRSAKERVFVTNALRALRQV..SPTGNIRDI.PFVVLVGGSSLDFEVPQLVTDALAHYR..LVAGRGNIRGVEGPRNAVATGLILSW..................................................................................................
A0A0V8JEA9_9BACI/276-603             ............................................................................................................................................VPINDGAERIMKAYENIGDLVDVQGEMGTNVGGMLNGLRQDLANLT.GQ..................DANDIHISDMLAVDAGIPTS.........ISGAMAGEIAMEQGVALASMVKTEKLS...VHK.VAD..LLQQ.RL......DVE.VEV..GG..I..EAEM.A.MRG..ALTTP.......GT.E.Q.PLVILDMGGGSTDAASID..HKGQI..T..T..T.H.L.A.G...A..G....D....M....VT....LVI......K..S......E..L....A......LE.D.....ADLAEKIK.K.YPLGKVISLFHMQLEDGTISFTE.TPYAPETYGKVVIR.ED.SGLTPL..PIRDSLEKIRHVRREAKRKVFVTNALRALEKV..SPTQNLRHL.SFVVMLGGSALDFEIPQMITEELSKYS..IVAGFANTRGTEGPRNAVATGLILS-v.................................................................................................
R9KL89_9FIRM/274-601                 ............................................................................................................................................VDVDAGGEKIMQAVESLPVLEDVRGEPGTNAGGMLEKVRQVMANLT.KQ..................HPKDIHIQDLLAVDTFTPQK.........VQGGLANEFSQENAVGIAAMVKADRLQ...MEA.IAR..EFSE.QI......GIP.VHV..GG..V..EADM.A.IRG..ALTTP.......GT.N.K.PLAILDMGAGSTDASIIS..REGEI..H..S..I.H.L.A.G...A..G....N....M....VT....LLI......Q..S......E..M....G......LD.S.....FDIAEDVK.K.YPLAKVESFFHIRHENGTVEFFP.EPLDPNIFAKTIIL.KD.GNMIPL..EGDWSMEKIRLIRRQAKQKVFVTNALRALSRV..SPTGNVRDI.QFVVLVGGSALDFEVPQMVTDALAQYK..VVAGRGNIRGTEGPRNAVATGLVLS-l.................................................................................................
E3HDB0_ILYPC/274-601                 ............................................................................................................................................VRVDRGSKEIMSAIKACHPVNDIYGETGTNAGGMLEKVRVVMAQLT.DQ..................NVKNIKIQDLLAVDTFVPQK.........VVGGMAGEFAMENAIGVAAMVKADKLQ...MKM.VAS..NLEE.KL......DIA.VEV..GG..V..EAEM.A.IIG..SLTTP.......GT.T.K.PLAILDMGAGSTDASIIT..KSGEI..S..S..C.H.L.A.G...A..G....N....M....VT....MLI......D..R......E..L....G......LG.D.....FDLAEDIK.K.YPLAKVESLFHIRHEDGSVQFFD.TQLDPGIFARIVIL.KD.GEMQPL..EIDGNIEKIKNIRREAKKKVFVENGIRALVRI..SPTSNIRDI.DYVVLVGGSALDFEIPQMITDSLAHYG..IVAGRGNIRGVEGPRNAVATGLSLSY..................................................................................................
R6G8Y1_9FIRM/273-601                 ............................................................................................................................................VGVEEGAEKMMEAVNSVPVIEDIKGEPGTNAGGMLEKVRQVMSNLT.NQ..................HPKDIKIQDLLAVDTYNPQK.........IKGGLANEFSLESAVGIAAMVKADRLQ...MKM.IAE..ELTD.RL......KIP.VYV..GG..V..EADM.A.IKG..ALTTP.......GT.N.V.PLAIVDMGAGSTDASIKD..RDGNV..K..L..V.H.L.A.G...A..G....N....M....VT....LLI......Q..S......E..L....G......LE.D.....FNTAEDIK.K.YSLAKVESLFHIRHEDGTVQFFE.QPLDPNVFAKVVLV.KEdGELVPL..EGQDSMEKIKMVRTNAKKKVFVTNAIRSLAKV..SPTGNVRDI.EFVVLVGGSALDFEVPTLVTDALSQYN..IVAGRGNIRGCEGPRNAVATGLAMS-c.................................................................................................
A0A0A7FXY5_9CLOT/279-606             ............................................................................................................................................VDVEHGASKIMDAVKLCVPIQDVKGEAGTNAGGMLERVRQVMANLT.KQ..................KITDIKIQDLLAVDTFIPQK.........VKGGLAEEFSLENAVGIAAMVKADKLQ...MQM.IAD..ELEK.EL......KVP.VEV..GG..V..EADM.A.IRG..ALTTP.......GT.S.T.PLAILDMGAGSTDASIIN..KNNEI..S..S..I.H.L.A.G...A..G....N....M....VT....MLI......K..S......E..L....G......LE.S.....FNLAEDIK.K.YPLAKVESLFHIRHEDGTVEFFE.EPLDPSVFAKVVII.KD.GMLVPI..DGQTSIEKIRNIRRSAKEKVFVTNCLRALSIV..SPTGSIRDI.EFVVLVGGSSLDFEVPQLVTDALSQYG..VVAGRGNIRGTEGPRNAVATGLILA-c.................................................................................................
A0A099S494_9CLOT/272-599             ............................................................................................................................................ISIEEGALAIMNSLDKVWPLEDVSGEPGTNVGGMIERVRQVMSELT.NQ..................DTEEIKIQDVLAVDTFIPQK.........VQGGLAEEFALENAVALAAMVKTSKLP...MEN.IAQ..KLES.ET......NVK.VLI..GG..V..EAGM.A.VLG..ALTTP.......GT.D.K.PLVILDMGGGSTDSAYID..KNNTV..K..S..I.H.H.A.G...A..G....E....M....VT....MLI......K..S......E..L....G......LE.D.....YNLAEDIK.K.FPLAKVESLFNIRYEDGSVCFFQ.QPLDSNLFARNIVV.KK.DEMIPI..PTKHAIEKIRIVRREAKRKVFVTNAIRALKDI..APNHDLRSI.DFVVLVGGSALDFEVPEMISDELSHYG..VVCGGGNIRGIEGPRNAVATGLVISY..................................................................................................
D5XBU6_THEPJ/275-603                 ............................................................................................................................................VDIQAGAEKVQEVIESAGKLEDVRGEPGTNVGGMIERIRHVMSDLT.NQ..................PVHNMKIQDILAVDTFIPQK.........VQGALAGEFSLENAVGLAAMVKTNKLQ...MQE.IAE..KLAG.EL......GIK.VEI..AG..V..EAEM.A.VRG..ALTTP.......GS.D.R.PLAILDMGGGSTDAAIID..REGHI..N..S..V.H.L.A.G...A..G....D....M....VT....LLI......N..S......E..L....G......LD.N.....PGLAEEIK.R.YPLAKVESLYHIRTEDGSVQFFD.KALDPRLFARVVIL.KEkGVMEPI..PVKDSLEKIKLIRQEAKKKVFVTNAVRALQRV..APHGNIRNV.EFVVMVGGSALDFEIPGFISDRLAEYG..VVAGRGNIRGQAGPRNAVATGLVLSY..................................................................................................
W1DMB2_KLEPN/1-162                   ............................................................................................................................................----------------------------------------------.--..................--------------------.........---------------------------...---.---..----.--......---.---..--..-..----.-.---..-----.......--.-.-.------------------..-----..-..-..-.-.-.-.-...-..-....-....M....VS....LLI......K..T......E..L....G......LE.D.....LSLAEAIK.K.YPLAKVESLFSIRHENGAVEFFR.EALSPAVFAKVVYI.KE.GELVPI..DNASPLEKIRLVRRQAKEKVFVTNCLRALRQV..SPGGSIRDI.AFVVLVGGSSLDFEIPQLITEALSHYG..VVAGQGNIRGTEGPRNAVATGLLL--ag................................................................................................
#=GC seq_cons                        ............................................................................................................................................VslstGA-tIMpslppstslpDlpGEsGTNlGGMLc+VRpsMupLT.sp..................s.p-ItIpDLLAVDThlP.c.........VpGGLAuEFuhEsAVulAuMVKoc+L....Mph.IAc..plpp.cL......slt.Vpl..GG..s..EA-h.A.lhG..ALTTP.......GT.s.t.PlAILDhGuGSTDAulIs..tcGpl..t..u..l.H.L.A.G...A..G....-....M....VT....hlI......s..o......E..L....G......Lp.-.....htLAE-IK.+.YPLAKVESLFplRaEDGoVpFF-.pPLssplFARVVll.cs.sthlPl..sschulEKlRtlRRpAKc+VFVsNAlRALcpV..uPsGNlRcI.sFVVLVGGSALDFEIPphlT-ALucYs..lVuGRGNIRGsEGPRNAVATGLlLu...................................................................................................
//
DBGET integrated database retrieval system