GenomeNet

Database: Pfam
Entry: DEC-1_N
LinkDB: DEC-1_N
Original site: DEC-1_N 
#=GF ID   DEC-1_N
#=GF AC   PF04625.10
#=GF DE   DEC-1 protein, N-terminal region
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04594;
#=GF GA   27.90 27.90;
#=GF TC   28.50 78.70;
#=GF NC   26.40 27.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   1699826
#=GF RT   Multiple proteins are produced from the dec-1 eggshell gene in
#=GF RT   Drosophila by alternative RNA splicing and proteolytic cleavage
#=GF RT   events. 
#=GF RA   Waring GL, Hawley RJ, Schoenfeld T; 
#=GF RL   Dev Biol 1990;142:1-12.
#=GF DR   INTERPRO; IPR006719;
#=GF CC   The defective chorion-1 gene (dec-1) in Drosophila encodes
#=GF CC   follicle cell proteins necessary for proper eggshell assembly.
#=GF CC   Multiple products of the dec-1 gene are formed by alternative
#=GF CC   RNA splicing and proteolytic processing [1].  Cleavage products
#=GF CC   include S80 (80 kDa) which is incorporated into the eggshell,
#=GF CC   and further proteolysis of S80 gives S60 (60 kDa).
#=GF SQ   18
#=GS B4JK38_DROGR/204-546  AC B4JK38.1
#=GS B4MAG1_DROVI/178-516  AC B4MAG1.1
#=GS B3MRA8_DROAN/98-499   AC B3MRA8.1
#=GS B4L6A5_DROMO/191-536  AC B4L6A5.1
#=GS DEC12_DROME/74-480    AC P18170.2
#=GS B5DMT1_DROPS/83-479   AC B5DMT1.1
#=GS M9NG31_DROME/57-463   AC M9NG31.1
#=GS B4IL40_DROSE/74-479   AC B4IL40.1
#=GS M9NEY9_DROME/74-480   AC M9NEY9.1
#=GS DEC11_DROME/74-480    AC P18169.2
#=GS B4JK38_DROGR/87-254   AC B4JK38.1
#=GS B4NCW6_DROWI/87-501   AC B4NCW6.1
#=GS DEC13_DROME/74-480    AC P18171.2
#=GS M9NEA7_DROME/57-463   AC M9NEA7.1
#=GS B4GVW6_DROPE/83-479   AC B4GVW6.1
#=GS B4MAG1_DROVI/83-186   AC B4MAG1.1
#=GS B4L6A5_DROMO/89-242   AC B4L6A5.1
#=GS B4R683_DROSI/74-454   AC B4R683.1
B4JK38_DROGR/204-546             .............pp-----------------------------....--------------------.----------.IPAIP...PIPNTFNLGQMA.pNLA...NLG---...QMPNLGQM...PNLGQLpnLGQM.....ANLG..Q-M.AF.LGQA....APV.P...EASTTA...A.-PPTPKS....DDPsP.PAPSVAQAA.........PLfgGLFDGGN----..NFLGP....-..-------P----..--DALMAGL.RQFIPGGVVAPPAPA.GSSAQASDISEVRVKPAgepiM..........S...YrspqqtdAQLSQFRINTALRM----...QQREQEQDKQQMPLVWLRMPTedtdttkTQTKTETG..DKTDEphkprdRMEIEARLHAFQRQVIAELQQLQHIERLAREMRASA....QGASVTpTFKLRYPLSRTPVHKITRADIEGALRDDYVRRLLHKEALRK....T------.............-NYKRQT-ME.QQSMSKEDILKVMAYAYRVASESAEK---kane.......
B4MAG1_DROVI/178-516             ...pqvpagwlpdgf-----------------------------....--------------------.----------.-----...------TLGQMP..---...PLPDNFnlgQMPPLPDG...FNLGQM..APVMp...nFGLR..PLE.SL.LGQA....PVA.P...ATTAAP...P.AAKPASE....SEP.A.PAPAVGQAP.........PAagAGF-GALFDGS.nNLLGQ....A..FSGMPAAPTPDA..----FMAGL.RQFWPGAA---PPTG.DRSAQASDISEVRVKPD....NhnqdtigyraPqqaH.......AQLAQMKIKSALQLEQEK...---------QRVPLLWFRMPS.......SETQQ---..SKSTE......RAQIESKLQAFEQQVIAELQQLQQIERMAREMRANA....QGETPA.-YKLRYPLSRTPVHKITRADIERALRDDYVRRLLQKEAQRK....T------.............-NFKRQTQQQpEQLLTKEDIVKVMAYAYRMANENAER---kakeeq.....
B3MRA8_DROAN/98-499              ...............MMFPALGSLLRWGSVFPMGSLLGAVPDTL....LQPTGAASKVVLVLADDAAA.KTRVPRQDSP.PPPPN...PLDWAANVGQMI.tNMQ...ANP---...LLPPMPLD...ATLGAP..LQSL.....LPLG..SLT.GI.LGQA....APA.P...AVSADP...P.PPPAPVP....DTP.A.PAPASP---.........PF..SAFDPANLGQSitSMLSQappnF..LSQMPAVPQIPQ..-----LQQF.AQFLPQIPGLSQAPV.G---QASDISEVRVRPE....I..........P...Y......vTGTPQMKIKTALEKEQDRrreQEMDQEQDQERVPLLWFRLPV.......GHDRN-TQ..GKPIE......DLRVEAKLKAFERQVITELKMLQQIERMAKEMRTSAatgtAAQSSD.-YQLNYPLNHTPVHKITRADIEQALRDDYVRRLVQKEAQRR....GFINRKT.............GGYKRQAFAE.DKNLSKEEIVQIMAYAYRMANEQMAEAEK...........
B4L6A5_DROMO/191-536             qmmprppagwlpdgf-----------------------------....--------------------.----------.-----...------SLGQMP..---...PLPDNFnlgQMPPMPPMpdaFNLGQM..APVMq...sFGLP..TLD.GL.LGQA....SAA.T...TTTPAP...PaAKPADEP....AAP.A.PAPAGPTLGqa....pppGF.gSFFDGSN----..NLLGS....A..LSGIPGAPTPD-..---SFMAGL.RQFLPG---------.-SSAQASDISEVRVKPEhhgsIny......raP...Qq....tqAQLAQLKIKSALQMEQEK...Q---------QVPLLWFRMPS.......KQENEEEQgdGKTTD......RAQIESKLEAFERQVIEELQQLQQIERLAREMRAHAq.geTARNGA.SYKLRYPLSRTPVHKITRADIERALRDDYVRRLLSREMQRR....TYTKRQI.............MT-----GQQ.PQSLSKEDIVKVMAYAYRMAAENAER---kakeq......
DEC12_DROME/74-480               ...............MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LAQL.....PAMP..TVP.GL.LGAAapvpAPA.P...APAAAP...P.PAPAPAA....DPPaA.PVPDAPQPAilgqaalqnAF..TFFNPANFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALEMEQER...QQQAQVKDQEQVPLLWFRMPT.......TQNQDATE..EKTLE......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA....AAQNGDsPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRarnsGINTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
B5DMT1_DROPS/83-479              ...............MLFPALGSLLRWGALFPAQSVLGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVTRQD-T.P--PA...PNAFGQLLAQMPnpNFAqgwMNPANF...NPDSFNLGqiaPNVGQA..LTTMq...lPPMPqfGFE.NI.LGAA....PPPpP...AVVPPP...P.AEPAPPA....APA.A.DEPAAPVAAp.......nPF..SFLTPNNFDVN..QLLGQ....A..QQALPPMPPMPAmpSNVDFFSNL.RQMWPGAPPASPGPApGSDGQASDISEVRVRPE....A..........-...-.......----------A-----DS...QENA-LDDKERVPLLWFRMPM.......NRQGDEGE..AKPLE......DLRVEAKLRAFERQVIAELKMLQQIERVAKEMRSSA....TSSSGS.PYKVSYPLSRTPVHKITRADIERALRDDYVRRLLHKEAQRK....SRANH--.............AAFKRQTMPS.EASMSKEDIVKIMAYAYRMATEQQSAA--qe.........
M9NG31_DROME/57-463              ...............MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LAQL.....PAMP..TVP.GL.LGAAapvpAPA.P...APAAAP...P.PAPAPAA....DPPaA.PVPDAPQPAilgqaalqnAF..TFFNPANFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALEMEQER...QQQAQVKDQEQVPLLWFRMPT.......TQNQDATE..EKTLE......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA....AAQNGDsPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRarnsGINTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
B4IL40_DROSE/74-479              ...............MMFPALGSLLRWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LTQL.....PAMP..SMP.GL.LGAA....APV.P...APAPAPaaaP.PAPAPAV....DPPaA.PAPDAAQPAilgqaalqnAF..TFLNPSNFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAPA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALQMEQER...QQQVQVKDQEQVPLLWFRMPT.......TQNLDTTE..EKTLE......DLRVEAKLRAFERQVIAELKMLQKIELMAKQMRSSA....AAQNGDtPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRKarnsGNNTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
M9NEY9_DROME/74-480              ...............MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LAQL.....PAMP..TVP.GL.LGAAapvpAPA.P...APAAAP...P.PAPAPAA....DPPaA.PVPDAPQPAilgqaalqnAF..TFFNPANFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALEMEQER...QQQAQVKDQEQVPLLWFRMPT.......TQNQDATE..EKTLE......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA....AAQNGDsPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRarnsGINTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
DEC11_DROME/74-480               ...............MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LAQL.....PAMP..TVP.GL.LGAAapvpAPA.P...APAAAP...P.PAPAPAA....DPPaA.PVPDAPQPAilgqaalqnAF..TFFNPANFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALEMEQER...QQQAQVKDQEQVPLLWFRMPT.......TQNQDATE..EKTLE......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA....AAQNGDsPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRarnsGINTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
B4JK38_DROGR/87-254              ..............s-MFPALSSLLRWGSLFPAQSVLGAVPDTL....-QP--AASKVVLVLADEANGhKSRRTRQDTP.APTPA..aP----AAPGAML..---...---QQ-...FLSQMPSP...ANLQQM..MPQL.....PTGW..LPD.NFqLGQM....PPM.P...DLGQMP...P.IPPIPAI....---.P.PIPNTFNLG.........QM..-APNLANLGQM..PNLGQ....MpnLGQLPNLGQMA-..---------.---------------.-----------------....-..........-...-.......------------------...---------------------.......--------..-----......------------------------------------....------.-----------------------------------------....-------.............----------.-----------------------------nlgq.......
B4NCW6_DROWI/87-501              ...............MLFPALGSLLRWGSLFPAHTILGAVPDSLpnvsTQPQAAASKVVLVLADDAQA.KSRVARQNAG.TPALN..gPDMFTSLLGQMA..---...--PQNLg.qMMSPESLGqfvPQVGQA..LQNFqlpqgLPFQ..GLD.NF.LG--....APL.P...VLGAPP...PtPAPAPTPkaasDDP.A.PAPATPPAG.........SF.aAFFNPSNFDAP..GLLGQ....M..QAQLPPLPAAPA..GTPDFMAGL.RQFWPG-AAASGGAA.GSDAQASDISEVRVKPG....-..........-...-.......EQLAQLKIKTP-------...QDLDQDKEQENVPLLWFRLPI.......SQEESSEK..DKTTE......DLRIKNKLQAFERQVISELKLLQQIERLAKEMRAQA....SAQGAS.PYKLNYPLSRTPVHKITRADIERALRDDYVRRLLHKEAQRK....SWIGQKAkyirdeaagketgAALKRQT---.--NLSKDEIIKMMAYAYRMANEQQQQAE-ek.........
DEC13_DROME/74-480               ...............MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LAQL.....PAMP..TVP.GL.LGAAapvpAPA.P...APAAAP...P.PAPAPAA....DPPaA.PVPDAPQPAilgqaalqnAF..TFFNPANFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALEMEQER...QQQAQVKDQEQVPLLWFRMPT.......TQNQDATE..EKTLE......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA....AAQNGDsPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRarnsGINTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
M9NEA7_DROME/57-463              ...............MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LAQL.....PAMP..TVP.GL.LGAAapvpAPA.P...APAAAP...P.PAPAPAA....DPPaA.PVPDAPQPAilgqaalqnAF..TFFNPANFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALEMEQER...QQQAQVKDQEQVPLLWFRMPT.......TQNQDATE..EKTLE......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA....AAQNGDsPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRarnsGINTQKA.............NALKRQAKSQ.DQTLSKEDIVQIMAYAYRMANEQMESEK-g..........
B4GVW6_DROPE/83-479              ...............MLFPALGSLLRWGALFPAPTMLGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVTRQD-A.PP--A...PNAFGQLLAQMPnpNFAqgwMNPANF...NPDSFNLGqiaPNVGQA..LTNMq...lPPMPqfGFE.NI.LGAA....PPPpP...AVVPPP...P.AEPAPPA....APA.A.DEPAAPVAAp.......nPF..SFLTPNNFDVN..QLLGQ....A..QQALPPMPPMPAmpSNVDFFSNL.RQMWPGGPPANPGPApGSDGQASDISEVRVRPE....-..........-...-.......---------AA-----DS...QENDL-DDKERVPLLWFRMPM.......NRQGDEGE..AKPLE......DLRVEAKLRAFERQVIAELKMLQQIERVAKEMRSSA....TSSSGS.PYKVSYPLSRTPVHKITRADIERALRDDYVRRLLHKEAQRK....SRANH--.............AAFKRQTMPS.EASMSKEDIVKIMAYAYRMATEQQSAA--qe.........
B4MAG1_DROVI/83-186              ...............LMFPALSSLLRWGSLFPAQSLLGAMPDTL....-QP--AASKVVLVLADEANGhKSRVTRQDATaQPAPA...AAAPTAMNGPAM..-LQ...QMQQML..gQMPPPNLG...QMLPQ-..----.....----..---.--.----....---.-...------...-.-------....---.-.---------.........--..-----------..-----....-..------------..---------.---------------.-----------------....-..........-...-.......------------------...---------------------.......--------..-----......------------------------------------....------.-----------------------------------------....-------.............----------.-----------------------------vpagwlp....
B4L6A5_DROMO/89-242              ..............f-MFPALSSLLRWGSLFPAQTLLGAVPDNL....---QASPSKVVLVLADDANGhKSRVTRQDAA.PAAPAppaPAPPGALNGAAM..-LQ...QMQQML..gQMPPPNLA...QMVPPN..LAQMm..prPPAG..WLPdGFsLGQM....PPL.PdnfNLGQMP...P.MPPMPDA....---.-.---------.........--..-----------..-----....-..------------..---------.---------------.-----------------....-..........-...-.......------------------...---------------------.......--------..-----......------------------------------------....------.-----------------------------------------....-------.............----------.-----------------------------fnlgqmapvmq
B4R683_DROSI/74-454              ...............MMFPALGSLLRWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-PPPN...PL------GQLM..NWP...ALPQDF...QLPSMDLG...PQVGSF..LSQLp..amPAMP..SMP.GL.LGAA....APV.P...APAPAPaaaP.PAPAPAA....DPP.ApPAPDAAQPAilgqaalqnAF..TFLNPSNFDAS..SLLGQ....-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAPA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKSALQMEQER...QQQVQVKDQEQVPLLWFRMPT.......TQNHDATE..EKTLE......DLRVEAKLRAFERQVIAELKMLQKIELMAKQMRSSA....AAQNGDtPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRKarnsGVNTQKA.............NALKRPGF--.-----------------------------sfc........
#=GC seq_cons                    ...............MMFPALGSLL+WGSLFPA.SlLGAlPDsL.....QPTAAASKVVLVLADDAsA.KTRVsRQs....PsPs...Ph......GQhh..Nhs...sLPQsF...QhPsMsLG...PpVGph..LsQh.....PshP..sls.Gl.LGtA....APs.P...AsussP...P.ssPAPsu....DsP.A.PsPsuPpsA........ssF..oFFsPuNFDss..sLLGQ............ulPshss..ss.DFhAph.RQFaPGhssApPusA.GoDAQASDISEVRVRPE...............P...a.......uQ.AQhKIKoALphEQ-+...QppsQ.cDpEpVPLLWFRMPo.......oQsp-tsc..pKTlE......DLRVEAKL+AFERQVIAEL+MLQpIEhhAKpMRoSA....sApsGs.PY+lsYPLSRTPlHKITRADIEpALRDDYVRRLlpKEAQR+....uhsspph.............sAhKRQsh.p.-poLSKEDIVplMAYAYRMAsEQhppt..t..........
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