GenomeNet

Database: Pfam
Entry: DNA_ligase_OB_2
LinkDB: DNA_ligase_OB_2
Original site: DNA_ligase_OB_2 
#=GF ID   DNA_ligase_OB_2
#=GF AC   PF14743.3
#=GF DE   DNA ligase OB-like domain
#=GF AU   Eberhardt R
#=GF SE   CATH:1fvi_A_02
#=GF GA   28.00 28.00;
#=GF TC   29.10 28.60;
#=GF NC   27.70 27.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12930960
#=GF RT   Analysis of the DNA joining repertoire of Chlorella virus DNA
#=GF RT   ligase and a new crystal structure of the ligase-adenylate
#=GF RT   intermediate.
#=GF RA   Odell M, Malinina L, Sriskanda V, Teplova M, Shuman S;
#=GF RL   Nucleic Acids Res. 2003;31:5090-5100.
#=GF RN   [2]
#=GF RM   11106756
#=GF RT   Crystal structure of eukaryotic DNA ligase-adenylate illuminates
#=GF RT   the mechanism of nick sensing and strand joining.
#=GF RA   Odell M, Sriskanda V, Shuman S, Nikolov DB;
#=GF RL   Mol Cell. 2000;6:1183-1193.
#=GF RN   [3]
#=GF RM   17618295
#=GF RT   Structural basis for nick recognition by a minimal pluripotent
#=GF RT   DNA ligase.
#=GF RA   Nair PA, Nandakumar J, Smith P, Odell M, Lima CD, Shuman S;
#=GF RL   Nat Struct Mol Biol. 2007;14:770-778.
#=GF DR   INTERPRO; IPR029319;
#=GF CC   This domain has an OB-like fold, but does not appear to be
#=GF CC   related to Pfam:PF03120. It is found at the C-terminus of the
#=GF CC   ATP dependent DNA ligase domain Pfam:PF01068 [1-3].
#=GF SQ   178
#=GS A0A0B5CFP4_NEIEG/206-270  AC A0A0B5CFP4.1
#=GS S7S359_GLOTA/336-400      AC S7S359.1
#=GS A0A0D1EA68_USTMA/620-683  AC A0A0D1EA68.1
#=GS F9TDV7_9VIBR/216-281      AC F9TDV7.1
#=GS B9KEB9_CAMLR/238-306      AC B9KEB9.1
#=GS D0NB14_PHYIT/427-491      AC D0NB14.1
#=GS I0HUB6_RUBGI/213-278      AC I0HUB6.1
#=GS F5ZEK7_ALTSS/265-330      AC F5ZEK7.1
#=GS Q9KRU2_VIBCH/214-279      AC Q9KRU2.1
#=GS D2XA80_GBMV/332-401       AC D2XA80.1
#=GS H2FX73_OCESG/210-275      AC H2FX73.1
#=GS B0UW96_HISS2/203-266      AC B0UW96.1
#=GS A0CCG0_PARTE/348-413      AC A0CCG0.1
#=GS D5GLS4_TUBMM/170-240      AC D5GLS4.1
#=GS E1SR63_FERBD/212-276      AC E1SR63.1
#=GS G4SZS2_META2/215-280      AC G4SZS2.1
#=GS A0A073CAP5_PLAAG/210-282  AC A0A073CAP5.1
#=GS Q5E4V1_VIBF1/217-282      AC Q5E4V1.1
#=GS Q6WI94_BPKVM/354-430      AC Q6WI94.1
#=GS F0LTS5_VIBFN/214-279      AC F0LTS5.1
#=GS Q084H9_SHEFN/214-279      AC Q084H9.1
#=GS S6AFN5_9PROT/184-250      AC S6AFN5.1
#=GS M7WM38_RHOT1/461-527      AC M7WM38.1
#=GS Q5HMU4_STAEQ/354-423      AC Q5HMU4.1
#=GS Q5KHG3_CRYNJ/597-667      AC Q5KHG3.1
#=GS Q4DIW5_TRYCC/146-216      AC Q4DIW5.1
#=GS B1KQN5_SHEWM/216-281      AC B1KQN5.1
#=GS K0C6K3_CYCSP/207-271      AC K0C6K3.1
#=GS K5VYZ6_AGABU/632-696      AC K5VYZ6.1
#=GS A4V7V3_PSEFS/350-426      AC A4V7V3.1
#=GS C9R5J9_AGGAD/166-229      AC C9R5J9.1
#=GS V2YHU7_MONRO/520-584      AC V2YHU7.1
#=GS A6VNK5_ACTSZ/206-270      AC A6VNK5.1
#=GS Q5QUG2_IDILO/220-285      AC Q5QUG2.1
#=GS K4E8W2_TRYCR/432-502      AC K4E8W2.1
#=GS Q57VQ7_TRYB2/403-473      AC Q57VQ7.1
#=GS G4ZB68_PHYSP/389-453      AC G4ZB68.1
#=GS S8C735_DACHA/451-517      AC S8C735.1
#=GS D7DMI7_METV0/218-283      AC D7DMI7.1
#=GS A1W9H7_ACISJ/233-298      AC A1W9H7.1
#=GS Q4Q959_LEIMA/354-424      AC Q4Q959.1
#=GS Q30T18_SULDN/205-270      AC Q30T18.1
#=GS G4QIH1_GLANF/225-293      AC G4QIH1.1
#=GS A1SU29_PSYIN/211-276      AC A1SU29.1
#=GS F2GA10_ALTMD/245-310      AC F2GA10.1
#=GS Q8EF01_SHEON/237-302      AC Q8EF01.1
#=GS B1Y8A7_LEPCP/235-299      AC B1Y8A7.1
#=GS L8WJ26_THACA/469-526      AC L8WJ26.1
#=GS A4HEY9_LEIBR/552-624      AC A4HEY9.1
#=GS D0J638_COMT2/201-267      AC D0J638.1
#=GS K6YZZ0_9ALTE/223-294      AC K6YZZ0.1
#=GS I1C2P4_RHIO9/389-459      AC I1C2P4.1
#=GS Q6BFC7_PARTE/210-272      AC Q6BFC7.1
#=GS K1PDV0_CRAGI/408-473      AC K1PDV0.1
#=GS M4RAH6_BIBTR/201-265      AC M4RAH6.1
#=GS Q0P7W0_CAMJE/213-278      AC Q0P7W0.1
#=GS B6BKK3_SULGG/197-262      AC B6BKK3.1
#=GS C5ZXL9_9HELI/208-276      AC C5ZXL9.1
#=GS I1XH95_METNJ/215-280      AC I1XH95.1
#=GS A7GWV3_CAMC5/234-300      AC A7GWV3.1
#=GS K1W0B7_TRIAC/343-407      AC K1W0B7.1
#=GS I1YJP8_METFJ/187-252      AC I1YJP8.1
#=GS F7YJ73_VIBA7/220-285      AC F7YJ73.1
#=GS A8ESN9_ARCB4/219-281      AC A8ESN9.1
#=GS U5HDG8_USTV1/496-561      AC U5HDG8.1
#=GS K0I2P5_9BURK/215-280      AC K0I2P5.1
#=GS S2J9A1_MUCC1/380-450      AC S2J9A1.1
#=GS A8Q7S3_MALGO/263-334      AC A8Q7S3.1
#=GS G8QMJ2_AZOSU/213-278      AC G8QMJ2.1
#=GS G4TJJ0_PIRID/353-416      AC G4TJJ0.1
#=GS B0DDS4_LACBS/789-853      AC B0DDS4.1
#=GS A4I264_LEIIN/354-424      AC A4I264.1
#=GS F4HEP5_GALAU/202-266      AC F4HEP5.1
#=GS A4I263_LEIIN/549-621      AC A4I263.1
#=GS E6WRV8_PSEUU/214-279      AC E6WRV8.1
#=GS G1XJJ2_ARTOA/460-526      AC G1XJJ2.1
#=GS U4JXX2_9VIBR/213-278      AC U4JXX2.1
#=GS Q4DMH7_TRYCC/443-513      AC Q4DMH7.1
#=GS D8PMU8_SCHCM/310-374      AC D8PMU8.1
#=GS M1FJJ3_9ALTE/216-281      AC M1FJJ3.1
#=GS M5DPP2_9GAMM/218-283      AC M5DPP2.1
#=GS G7UW13_PSEUP/214-279      AC G7UW13.1
#=GS C7RND4_ACCPU/213-278      AC C7RND4.1
#=GS N6XRG9_9RHOO/210-275      AC N6XRG9.1
#=GS D3RMG9_ALLVD/245-310      AC D3RMG9.1
#=GS A1WNL0_VEREI/265-330      AC A1WNL0.1
#=GS Q5F595_NEIG1/207-271      AC Q5F595.1
#=GS A1U6Z5_MARHV/222-287      AC A1U6Z5.1
#=GS C5CLV4_VARPS/213-278      AC C5CLV4.1
#=GS R4YNR5_OLEAN/210-283      AC R4YNR5.1
#=GS Q47GP0_DECAR/212-277      AC Q47GP0.1
#=GS M9MG52_PSEA3/751-815      AC M9MG52.1
#=GS A7I1G5_CAMHC/205-271      AC A7I1G5.1
#=GS Q5NXR5_AROAE/236-301      AC Q5NXR5.1
#=GS U5HDG7_USTV1/512-577      AC U5HDG7.1
#=GS Q7Y5P5_BPSP6/229-306      AC Q7Y5P5.1
#=GS F2K2P6_MARM1/207-272      AC F2K2P6.1
#=GS Q31F09_THICR/196-261      AC Q31F09.1
#=GS C0QLK9_DESAH/215-279      AC C0QLK9.1
#=GS A1S744_SHEAM/214-279      AC A1S744.1
#=GS Q21YI4_RHOFT/230-295      AC Q21YI4.1
#=GS W0DVL5_MARPU/229-294      AC W0DVL5.1
#=GS R1D0P1_EMIHU/448-513      AC R1D0P1.1
#=GS D4ZLI4_SHEVD/217-282      AC D4ZLI4.1
#=GS G2DI14_9NEIS/203-267      AC G2DI14.1
#=GS A0A0C5WEN3_9GAMM/234-299  AC A0A0C5WEN3.1
#=GS Q15ZT3_PSEA6/211-275      AC Q15ZT3.1
#=GS A6VXW2_MARMS/210-275      AC A6VXW2.1
#=GS C4ZII3_THASP/230-295      AC C4ZII3.1
#=GS C5KL83_PERM5/224-289      AC C5KL83.1
#=GS A0A067BFN0_SAPPC/451-515  AC A0A067BFN0.1
#=GS V4JW06_9GAMM/240-305      AC V4JW06.1
#=GS B7VNV5_VIBTL/224-289      AC B7VNV5.1
#=GS L0DG54_SINAD/274-339      AC L0DG54.1
#=GS Q7UZI6_PROMP/357-435      AC Q7UZI6.1
#=GS A0A097QJT6_9VIBR/214-279  AC A0A097QJT6.1
#=GS I5B6F4_9DELT/200-265      AC I5B6F4.1
#=GS R9P4D2_PSEHS/762-826      AC R9P4D2.1
#=GS M9X4Q9_MANHA/203-267      AC M9X4Q9.1
#=GS I4MH72_9BURK/212-277      AC I4MH72.1
#=GS H5WI39_9BURK/222-287      AC H5WI39.1
#=GS K4E7Q5_TRYCR/409-479      AC K4E7Q5.1
#=GS F2UAM4_SALR5/583-648      AC F2UAM4.1
#=GS Q7MKZ3_VIBVY/212-277      AC Q7MKZ3.1
#=GS Q87PM4_VIBPA/212-277      AC Q87PM4.1
#=GS Q47VW9_COLP3/224-289      AC Q47VW9.1
#=GS A0A0B4XNV2_9GAMM/205-270  AC A0A0B4XNV2.1
#=GS K0CEZ9_ALCDB/216-281      AC K0CEZ9.1
#=GS B9TF49_RICCO/16-81        AC B9TF49.1
#=GS A8H5J4_SHEPA/223-288      AC A8H5J4.1
#=GS A0A0D1E8A3_USTMA/713-777  AC A0A0D1E8A3.1
#=GS E6ZXQ4_SPORE/710-774      AC E6ZXQ4.1
#=GS Q0VKZ8_ALCBS/210-275      AC Q0VKZ8.1
#=GS A4G5U7_HERAR/224-289      AC A4G5U7.1
#=GS D1B3Z1_SULD5/203-268      AC D1B3Z1.1
#=GS A0C1A3_PARTE/348-413      AC A0C1A3.1
#=GS B6V2K8_BPSP1/345-420      AC B6V2K8.1
#=GS A0A0D2WMT9_CAPO3/496-561  AC A0A0D2WMT9.1
#=GS A0A0A7EF20_9GAMM/207-272  AC A0A0A7EF20.1
#=GS V3ZA01_LOTGI/425-490      AC V3ZA01.1
#=GS D4KCE0_9FIRM/360-434      AC D4KCE0.1
#=GS A1VNV0_POLNA/223-293      AC A1VNV0.1
#=GS U9U428_RHIID/450-514      AC U9U428.1
#=GS G0ACU4_COLFT/226-290      AC G0ACU4.1
#=GS A3QDA6_SHELP/202-267      AC A3QDA6.1
#=GS A2SFI2_METPP/223-287      AC A2SFI2.1
#=GS O41026_PBCV1/225-293      AC O41026.1
#=GS O41026_PBCV1/225-293      DR PDB; 2Q2U D; 225-293;
#=GS O41026_PBCV1/225-293      DR PDB; 2Q2U A; 225-293;
#=GS O41026_PBCV1/225-293      DR PDB; 2Q2U B; 225-293;
#=GS O41026_PBCV1/225-293      DR PDB; 2Q2U C; 225-293;
#=GS O41026_PBCV1/225-293      DR PDB; 2Q2T A; 225-293;
#=GS O41026_PBCV1/225-293      DR PDB; 1P8L A; 225-293;
#=GS D3G0Z1_BACPE/155-219      AC D3G0Z1.1
#=GS V5EBF9_PSEBG/716-780      AC V5EBF9.1
#=GS A0RQQ3_CAMFF/199-265      AC A0RQQ3.1
#=GS Q4DIW6_TRYCC/443-513      AC Q4DIW6.1
#=GS Q6LIB5_PHOPR/225-290      AC Q6LIB5.1
#=GS B8QU68_BPPPB/226-295      AC B8QU68.1
#=GS I7GTY9_9HELI/211-275      AC I7GTY9.1
#=GS W0SK07_9RHOO/185-250      AC W0SK07.1
#=GS Q3SKL4_THIDA/238-303      AC Q3SKL4.1
#=GS Q4Q960_LEIMA/549-621      AC Q4Q960.1
#=GS Q3IES5_PSEHT/212-277      AC Q3IES5.1
#=GS Q12AV7_POLSJ/231-301      AC Q12AV7.1
#=GS H3HE25_PHYRM/185-249      AC H3HE25.1
#=GS Q4DMH8_TRYCC/409-479      AC Q4DMH8.1
#=GS G0QN32_ICHMG/641-706      AC G0QN32.1
#=GS A1KA91_AZOSB/230-295      AC A1KA91.1
#=GS DNLI_HAEIN/203-267        AC P44121.2
#=GS A4HEZ0_LEIBR/398-468      AC A4HEZ0.1
#=GS D6XJX8_TRYB2/435-505      AC D6XJX8.1
#=GS A0A0D2VWS6_CAPO3/558-629  AC A0A0D2VWS6.1
#=GS I3YDC4_THIV6/241-306      AC I3YDC4.1
#=GS I2G232_USTH4/727-791      AC I2G232.1
#=GS U4LWK6_PYROM/338-408      AC U4LWK6.1
#=GS Q1DEP0_MYXXD/283-348      AC Q1DEP0.1
#=GS Q233G4_TETTS/487-552      AC Q233G4.1
#=GS D5V319_ARCNC/200-262      AC D5V319.1
#=GS A0EC59_PARTE/331-396      AC A0EC59.1
#=GS Q65U14_MANSM/182-246      AC Q65U14.1
#=GS K3WC20_PYTUL/523-587      AC K3WC20.1
#=GS Q9JXH4_NEIMB/207-271      AC Q9JXH4.1
#=GS A8P6S5_COPC7/656-720      AC A8P6S5.2
A0A0B5CFP4_NEIEG/206-270             ..........EGKGKYAGKLGAVGCRN.-......E....LG...E..FRI.GSGFKDADRAN..........PPPVGSVI..TYRYRGFT..QKGK......PRFATFLRIR.................
S7S359_GLOTA/336-400                 ..........PGKGKHKGSTGALKCKM.A......S....GK...A..FSV.GSGLSDKQRRS..........PPKVGAII..TYRFQELT..KDGV......PRFPTFI---ge...............
A0A0D1EA68_USTMA/620-683             .....ggrfq-----EHKAMASIQIEH.-......K....GT...R..VSV.GSGFTPDQRVEfa.....ndpDKIVGKIV..TVEYFDES..KT--......----------tvgtsg...........
F9TDV7_9VIBR/216-281                 .........v-GNGKYKGQMGALLVQL.E......S....GE...Q..FYI.GSGFSDVQRMN..........PPEIGSKI..TFRYNGYT..SSGL......PRFARYMRER.................
B9KEB9_CAMLR/238-306                 ..........EGKGKFEGKMGSLLCEA.Ni...ndK....KV...N..FKI.GSGFKESDRLN..........PPPIGSII..TFKYNGLS..KNGK......PKFASFLRV-h................
D0NB14_PHYIT/427-491                 .........d-GKGKYVGMVGALRCRM.S......S....GK...M..FKV.ASGLSDQQRDK..........PPAIGSII..VYKCQELT..NDGN......PRFPVFVGI-.................
I0HUB6_RUBGI/213-278                 .........g-GQGRLEGRMGALRVRA.D......D....GT...E..FLL.GTGFSDAERAA..........PPPVGTVV..SYRYRGRT..AAGV......PRFASFLRVR.................
F5ZEK7_ALTSS/265-330                 ..........KGKGKFAGMMGSLMVET.P......E....GV...Q..FKI.GTGFSMKQRRY..........PPPMNSWI..TFKYFGVT..KKGI......PRFASFRHVR.................
Q9KRU2_VIBCH/214-279                 .........l-GMGKYKGKMGSMLVRT.A......E....GL...E..FYI.GSGFSDVERAE..........PPKIGSVI..TYRYNGLT..TEGK......PRFARFVRVR.................
D2XA80_GBMV/332-401                  eggtedgaci------------FVLET.E......T....GD...T..FTCrPTGTIESRREMyk......krKRLIGKMV..TVTYQGRN.eETQV......PRFPRAKAIR.................
H2FX73_OCESG/210-275                 ..........PGQGRLEGMMGALLVET.V......D....GR...R..FKL.GTGFSDEQRRH..........PPAPGTLV..TYRYRGET..ATGL......PRFASFWRVR.................
B0UW96_HISS2/203-266                 ..........QGKGQFENMLGSISCQN.-......H....RG...I..FKI.GSGFNLIERRN..........PPPIGSII..TYKYRGLT..KNGL......PRFATYWR--s................
A0CCG0_PARTE/348-413                 .........s-GMGKFKDQLGALKVQT.D......A....GI...T..FQI.GVGFNSKLRKD..........PPKIGSRV..SYTYYGLT..DDGK......PRFPVFERIR.................
D5GLS4_TUBMM/170-240                 .........r-GSGKNSNCTGALRVEM.LddngepT....GK...F..FKI.GTGLTDKQRQN..........PPKIGIIV..IYRFQELS..RDGN......PRFPAHM---vf...............
E1SR63_FERBD/212-276                 ..........PGQGRLTGMMGSLIVED.A......Q....GR...R..FRL.GSGFSDEQRLS..........PPPVGTVV..TYSYSGRT..EAGL......PRFARFERI-.................
G4SZS2_META2/215-280                 ..........PGKGQFAGKMGSLKVRT.E......N....GK...E..FYI.GTGFSQREREA..........PPPLGSLI..SFRHQGYT..DKGI......PRFAVFIRIR.................
A0A073CAP5_PLAAG/210-282             ..........KGTGKYSGSLGKISVQA.D......I...lGV...PvaARV.GTGFTDAERLEiw.....nnqSNYRGRQL..EVIHLGLT..KTHS......IRHPVFSRF-.................
Q5E4V1_VIBF1/217-282                 .........d-GKGKFRGMVGAMILRM.P......N....GK...E..FKV.GSGLSIEVREN..........PPKLGSTV..TYRYNGYT..DNGI......PRFARYVAVR.................
Q6WI94_BPKVM/354-430                 ..........EGDKKNKGKMGALLLRS.A......C....GK...L.iTKV.GSGFTDKDREEiw.....arrDEVIGMIV..EINYNAIT..RA--......----------rnkdtwscflpifvqfr
F0LTS5_VIBFN/214-279                 .........f-GNGKYKGMMGSLLVRT.D......E....GT...E..FYV.GTGFTDEQRQN..........PPEIGSLI..TYRYNGLT..AEGK......PRFARFVRFR.................
Q084H9_SHEFN/214-279                 ..........EGKGKYRGKLGALIVKT.P......A....GV...V..FNI.GSGLSDKQREN..........PPLVGSTI..TYQYLGLT..QKGT......PRFATFLRQR.................
S6AFN5_9PROT/184-250                 ..........PGKGKHQGVLGALLVET.A......A....GL...R..FRI.GTGFSDAQRRN..........PPAPGSWV..TYRHIGLN.eESGI......PRFASFMRVR.................
M7WM38_RHOT1/461-527                 ..........PGKGKYEGMLGSLVCVM.E......D....RK...T.qFKV.GSGLNDDRRVN..........PPPIGSII..TYRFQELT..QQNV......PRFPTFVGER.................
Q5HMU4_STAEQ/354-423                 .......vrg-------NKVGNIVVDY.-......K....GY...E..LGV.GSGFSDKDRKLfw.....eqkDLIEGKIV..EISYFEES..KNDKgg..esLRFPVFKMVR.................
Q5KHG3_CRYNJ/597-667                 ......dehe--------ALASVWIEH.-......K....GH...P..VSV.GSGFSAEERLRya.....ekpEEIVGKTI..TVEYFSES.eAIGReg.aksLRFPRVKA--i................
Q4DIW5_TRYCC/146-216                 ..........EGRGKWKGCLGAFVCRT.K......R....GH...Q..FTV.APATTEQRKKDmw.....qrlAQYKGKML..TVQYQELS..ANGV......PRFPIGKCVR.................
B1KQN5_SHEWM/216-281                 ..........PGKGQFSGLLGALLVET.P......E....GV...R..FKI.GTGFSLEERRQ..........PPKLGDII..TYKYLGFT..QKGT......PRFASFLRVR.................
K0C6K3_CYCSP/207-271                 ..........PGKGQYQGKMGSILCLT.S......Q....GK...Q..LTI.GSGFSNKDRTD..........PPLIGSQI..TFKYYGLT..KKGR......YRFPVYLR--p................
K5VYZ6_AGABU/632-696                 .........d-GKGKHAGATGALKCRM.A......S....GK...T..FSV.GSGLSDKQRKS..........PPKIGSII..VYRFQELT..RDGV......PRFPTFVGI-.................
A4V7V3_PSEFS/350-426                 ..........KGKGKNAKTFGALECVS.-......E....CG...M..LEVnISGFSDELRLEif.....nnpERYIDSII..KVTFNDVT..KPNKktnlysLFLPRFG---elr..............
C9R5J9_AGGAD/166-229                 ..........KGKGQFESVMGSLTCEN.-......H....RG...Q..FKI.GSGFKLDDRIN..........PPPIGAVI..TYKYRGLT..NKGK......PRFATFWR--t................
V2YHU7_MONRO/520-584                 .........d-GKNKYKGVTGSLVCKM.E......S....GK...K..FNV.GSGLTDKQRKD..........PPKIGTII..TYRFQELT..KDGV......PRFPTFVG--e................
A6VNK5_ACTSZ/206-270                 ..........KGKGQFENALGSLTCEN.-......H....RG...R..FKI.GSGFNLEERIN..........PPPIGSVI..SYKYRGLT..NAGK......PRFATYWR--ek...............
Q5QUG2_IDILO/220-285                 ..........PGKGKYTDMLGALRVRN.Q......Q....GI...E..FSV.GTGFTDAERAN..........PPPVGSII..TYKYHGYT..SNGV......PRFASFLRIR.................
K4E8W2_TRYCR/432-502                 ..........PGQGKFRGGLGAFICET.K......T....GI...R..FNA.TPKTTYENRLAlw.....gkrQELLGKYL..TVQYQELS..SQDV......PRFPVAKAVR.................
Q57VQ7_TRYB2/403-473                 ..........EGKGKWRGCLGAFVCQT.R......A....GH...R..FTV.APATTEERKREmw.....hrlNVYKGKML..TVQYQELS..TNGV......PRFPIGKCVR.................
G4ZB68_PHYSP/389-453                 .........d-GEGKYVGMVGALRCRM.A......S....GK...M..FKV.ASGLSDAQRDK..........PPAIGSIV..VYKCQELT..NDGI......PRFPVFVG--l................
S8C735_DACHA/451-517                 ..........EGKGRNQGRCGALKCEM.M......D....GS...KktFKV.GTGLDDKTRKN..........PPKVGTVI..TYRYFELT..KDGV......PRFPSFMRV-.................
D7DMI7_METV0/218-283                 .........a-GQGKYKGKLGALEVET.P......E....GI...R..FKL.GTGFTDAQREN..........PPIIGSTV..TYTYRDKT..KAGK......PKFASFLRVR.................
A1W9H7_ACISJ/233-298                 ..........PGRGKYAGQTGALLVAL.P......D....GR...R..LRL.GSGLPDAVRRN..........PPPAGTVV..TYRFNGTH..ASGL......PRFARFWRVR.................
Q4Q959_LEIMA/354-424                 ..........PGEGKLKSALGAFVCTT.K......D....GK...Y..FHT.PPKVSCKRRIElw.....ehrSEYLGKYL..TVQYQELS..SQNV......PRFPIAKAIR.................
Q30T18_SULDN/205-270                 ..........EGKGKFKGLMGSLHVRV.E......S....GV...E..FFI.GSGFSDEDRKN..........PPKIGEIV..TFKYYGFT..KEGK......PKFASFMRVR.................
G4QIH1_GLANF/225-293                 ..........EGKGKYRDKVGAILVLY.S......Na..sGSk.iT..FKI.GSGFSDEERAN..........PPPIGSVV..TFKYHGFT..KRGV......PRFASYLRM-.................
A1SU29_PSYIN/211-276                 ..........PGKGRNAGRLGSLLVET.K......E....GI...K..FKI.GTGFSDLEREN..........PPPIGATI..TYKYTGKT..NNNV......PRFASFMRIR.................
F2GA10_ALTMD/245-310                 .........a-GKGKFQGMMGSLLVET.P......A....GV...Q..FKL.GTGFSEKERRA..........PPAVGSWV..TFKFYGVT..KNGK......PRFASFLRVR.................
Q8EF01_SHEON/237-302                 .........a-GKGQFSGKMGALRVQT.P......D....GR...I..FNI.GTGFNLAERQH..........PPAIGTLI..TYKYLGLT..VNGL......PRFASYLRIR.................
B1Y8A7_LEPCP/235-299                 ..........PGKGRHAGRLGALRVRT.P......D....GR...E..FAL.GSGLSDAERDD..........PPAPGRWV..TYRYRGLT..NSGL......PRFATFWRM-.................
L8WJ26_THACA/469-526                 ..........PGKGKHKGVTGALKCVM.A......S....GK...K..FSV.GSGLTDKQRRV..........PPKVGAIV..TYRFQELT..RDGV......PR--------.................
A4HEY9_LEIBR/552-624                 ..........EGSGKWKGFLGSFICVT.P.....dK....KH...R..FTV.TPASTDAEKRRmwq....swkTAYKGKVL..TVQYQEIT..PDGV......PRFPVGKCVR.................
D0J638_COMT2/201-267                 .........s-GRGQWQGMTGALLVQT.P......D....GK...Q..FSL.GSGLTAQMRKS..........PPALGSWV..TYRYQGLH.eKSGL......PRFARFLRVR.................
K6YZZ0_9ALTE/223-294                 .........s-GKGKYKNMMGSMLVEL.IelgesdR....GL...Q..FKI.GSGFSDMQRQS..........PPSIGTII..TFKYYGLT..ARGI......PRFASFLRI-k................
I1C2P4_RHIO9/389-459                 ......tgen------KLVLKNVNIEH.-......K....GN...T..VSV.GSGFSMNERIAfa.....enpSLIIGKAI..TVRYFSESvnKNGTi....sLRFPSIKA--i................
Q6BFC7_PARTE/210-272                 ........hm----KKENVLGGFLVRN.D......E....GQ...E..FEV.GLGLKIGIKKQ..........RPPIGTKI..TYKYCGLA..ENGY......PKFPEFVRI-.................
K1PDV0_CRAGI/408-473                 ..........PGKGRFQGKVGALRCKM.A......N....GK...L..FSV.GSGLTDKDHNR..........PPKIGSII..TYKFQEYT..NSGT......PRFPSYLGVR.................
M4RAH6_BIBTR/201-265                 ..........KGKGKYADKLGSITCEN.-......E....RG...R..FRI.GSGFKDKEREN..........PPAIGMVI..TYKYRGLT..ANGK......PRFATYWRER.................
Q0P7W0_CAMJE/213-278                 ..........KGKGKFENQVGALLCKM.P......N....GQ...I..IKI.GSGLKDEDRKN..........PPKIGSIV..TYKFNGLT..KNSL......PRFPVFLRIR.................
B6BKK3_SULGG/197-262                 ..........KGKGKYKGLVGSIVCKM.D......N....EQ...I..INI.GSGLNDEQRTR..........PPKIGAII..TFKYYGLT..SKGK......PRFPVFLHER.................
C5ZXL9_9HELI/208-276                 ..........QGKGKFKGMLGAIICQA.Nl...kgE....LK...T..FKI.GSGFTQKEREN..........PPPINSII..TYKYNGFT..KNNL......PRFPIFLRIR.................
I1XH95_METNJ/215-280                 ..........PGQGKYTGMLGALRVKN.Q......Q....GI...E..FSI.GTGFTDADRAN..........PPPIGSII..TYKYHGFT..KNDV......PRFASFLRIR.................
A7GWV3_CAMC5/234-300                 .........a-GQGKFSGLLGSVVCENlS......D....KK...R..FKI.GSGFSDEQRAN..........PPKIGSVI..TYKYQNLT..AKGL......PRFPVFLHVR.................
K1W0B7_TRIAC/343-407                 .........a---GRVQKACTSLTVDH.-......R....GH...P..VSV.GSGLSTAQRLRfv......dkAEIVGKQV..TVQYFEET..EKS-......LRFPTVKRV-.................
I1YJP8_METFJ/187-252                 ..........PGKGKYINQLGALRVKN.E......Q....GQ...I..FAI.GSGLSDQDRAS..........PPPIGTII..TYRYQGYT..KTGL......PRFARFIRIR.................
F7YJ73_VIBA7/220-285                 .........l-GSGKYQGMMGSVLVRL.E......N....GV...E..FYI.GSGFSDEIRNN..........PPKIGSII..TFRFNDLT..AEGK......PRFARFMRER.................
A8ESN9_ARCB4/219-281                 .......nyk------NGKFKSLVIKQ.K......D....GI...T..FNL.GNGFTNKDREN..........PPKIGDIV..TFKYYGLT..KNNK......PKFASFLRVR.................
U5HDG8_USTV1/496-561                 .........v-GTGKYIGETGSLICET.E......S....GK...R..FSV.GSGLSDAQRSD..........PPPIGSII..TYRFQNLT..TSRI......PRFPTYQGIR.................
K0I2P5_9BURK/215-280                 ..........PGQGRHAGRLGALVVEM.P......S....GQ...R..FRL.GAGLTDAERDH..........PPPVGSWV..TYRFRGTH..DSGV......PRFASFVRVR.................
S2J9A1_MUCC1/380-450                 ....tgetkl--------VVTNVNIEH.-......K....GY...P..VSV.GSGFSMQSRIDya.....qdpERIIGKTI..TVRYFSES..RKENgs..isLRFPTVKAV-.................
A8Q7S3_MALGO/263-334                 .........d-GQKGMAGFVGSFVCES.YndeyasE....TH...R..FRV.GSGLTDALRRH..........PPPIGTII..RYQYGGMG..SQGL......PRFPRYVGIR.................
G8QMJ2_AZOSU/213-278                 ..........PGKGRYAGMLGALRVEM.P......D....GR...R..FSL.GTGFSAAERRQ..........PPPVGALI..TYRYRELT..ATGL......PRFASYWRVR.................
G4TJJ0_PIRID/353-416                 ..........KGTGKNALVMGAIEVEM.A......S....GK...R..FKI.GTGFSDAQRRK..........PPKIGSIV..VYKFQELS..KSGT......PRFPVYV---g................
B0DDS4_LACBS/789-853                 ..........PGKGRNDGTTGALKCKM.A......S....GK...T..FNV.GTGLSDKQRRN..........PPKVGAII..VYRFQELT..RDGV......PRFPSYI---ge...............
A4I264_LEIIN/354-424                 ..........PGEGKFKSALGAFVCTT.K......D....GK...H..FNT.PPKVSCKHRIElw.....ehrREYLGKYL..TVQYQELS..SQNV......PRFPIAKAIR.................
F4HEP5_GALAU/202-266                 ..........KGKGQFHNVMGSLTCEN.-......E....RG...Q..FKI.GSGFSLADRAN..........PPAIGSVI..TYKYRGLT..KNGK......PKFATYWRQR.................
A4I263_LEIIN/549-621                 ..........EGSGKWKGFLGSFICVT.P.....dK....KH...R..FTV.TPASTDADKQRmwq....swkTVYKGKAL..TVQYQEIT..ADGV......PRFPVGKCVR.................
E6WRV8_PSEUU/214-279                 ..........PGKGRLEGRLGALQVRT.P......D....GR...S..FRI.GSGFSDAQRAD..........PPPIGSWV..TYRYSGLT..SKGL......PRFPRFLRIR.................
G1XJJ2_ARTOA/460-526                 ..........EGKGRNEGRCGALKCEM.M......Dg..tGK...K..FKV.GTGLDDNMRKN..........PPKIGSVI..TYRYFELT..KDGV......PRFPSFLRV-.................
U4JXX2_9VIBR/213-278                 ..........PGEGKYHGMLGSYFVRC.A......D....GK...E..FYI.GSGLKDSMRKD..........PLPVGARI..TYRFNGKT..STGK......PRFARFVRER.................
Q4DMH7_TRYCC/443-513                 ..........PGQGKFRGGLGAFICET.K......T....GI...R..FNA.TPKTTYENRLAlw.....gkrQELLGKYL..TVQYQELS..SQDV......PRFPVAKAVR.................
D8PMU8_SCHCM/310-374                 ..........PGKGKHTGATGALKCKM.A......C....GK...T..FNV.GTGMSDKQRAK..........PPKVGSII..TYRFQELT..KDGV......PRFPSFVG--e................
M1FJJ3_9ALTE/216-281                 ..........PGKGKYQGLMGALRVRL.A......D....NR...E..LRI.GSGFSDAERID..........PPPAGSVI..TFKYSGHT..ATGL......PRFASFMRVR.................
M5DPP2_9GAMM/218-283                 ..........PGEGRLQGMTGSLLLRL.D......D....GR...E..IRV.GSGLNDTLRHT..........PPALGTRI..TFAYNGLT..SSGL......PRFARFLRIR.................
G7UW13_PSEUP/214-279                 .........g-GKGKYAGLLGALLVQL.P......D....GR...S..FRI.GSGFTDAQRAA..........PPPLGAWV..TYRYNGLT..SKGL......PRFARFLHVR.................
C7RND4_ACCPU/213-278                 ..........PGRGKYAGMLGALRVRT.A......G....GV...E..FML.GTGLSDALRRD..........PPPIGTQI..TFRYRELT..DQGR......PRFASFQRLR.................
N6XRG9_9RHOO/210-275                 ..........PGKGRLQGKVGALEVET.D......D....GR...R..FRI.GSGLTDALRNT..........PPAIGTLV..TYRYRELT..PSGQ......PRFPRYVRER.................
D3RMG9_ALLVD/245-310                 ..........PGKGKYEGMLGALLVEE.P......S....GQ...R..FRL.GSGFSDAERRS..........PPPIGSRV..TFKYHGRT..RNGI......PRFASFLRVR.................
A1WNL0_VEREI/265-330                 ..........PGKGRHAGRLGALLVAM.P......S....GQ...R..FKL.GSGFSDAQRAD..........PPPVGSWV..TYRFRGLH..ESGL......PRFASFVRVR.................
Q5F595_NEIG1/207-271                 ..........EGKGRNAGRLGAVGCKN.-......R....HG...E..FRI.GSGFKDKDRDN..........PPKIGTLI..TYRYRGFT..RKGT......PKFATFVRVR.................
A1U6Z5_MARHV/222-287                 ..........PGKGKYEGLLGALEVEL.E......S....GR...R..FRL.GTGFTDEERHN..........PPAIGARV..TFRYRGLT..ATGL......PRFASFLRIR.................
C5CLV4_VARPS/213-278                 ..........PGKGRHSGRLGALLVET.P......E....GK...R..FKL.GSGLTDAEREN..........PPAIGSWV..TYRYNGTN..PGGL......PRFARFMRVR.................
R4YNR5_OLEAN/210-283                 ..........PGKGKYEGMMGAVWVEA.Sln..dnEgkliKQ...T..FKI.GSGFSDDDRKN..........PPAIGSEI..TFQYSGLT..STGK......PRFARYLRVR.................
Q47GP0_DECAR/212-277                 ..........PGKGRFAGHLGALKVRT.P......E....GR...E..FLL.GSGFSDLQRQQ..........PPAIGTTV..TYRFRDLT..NKGM......PRFASFLRVR.................
M9MG52_PSEA3/751-815                 .........n-GTGRHEGRTGSLVARM.E......C....GT...V..FRV.GTGLSDAQRDN..........PPPIGSII..NYRFFELS..EDGY......PRFPAFRG--i................
A7I1G5_CAMHC/205-271                 .........m-GNGKYSGKMGSLSCKNlK......N....GA...V..FKI.GSGFDDKLREN..........PPKIGDIV..TYKFQNLT..KNGK......PRFPVFLRIR.................
Q5NXR5_AROAE/236-301                 ..........PGKGRLQGMLGALEVET.P......D....GR...R..FRI.GTGFSDAQRRA..........PPAIGATV..TYRYRELT..AKGL......PRFPRYLRVR.................
U5HDG7_USTV1/512-577                 .........v-GTGKYIGETGSLICET.E......S....GK...R..FSV.GSGLSDAQRSD..........PPPIGSII..TYRFQNLT..TSRI......PRFPTYQGIR.................
Q7Y5P5_BPSP6/229-306                 ..........EGKGKYKGKVANLIFKW.K......G....GK...T.iKAMlGRGWTHEDATRmyhdikhggeLNVIGKIF..AIKALQES..SKGV......LRLPKVGELR.................
F2K2P6_MARM1/207-272                 ..........PGKGKFKNMMGALLVEM.P......T....GQ...R..FKI.GTGFTNVQRMN..........PPRVGDRV..TYKYFGFT..GTGL......PRFASFLRVR.................
Q31F09_THICR/196-261                 ..........PGKGKISGLVGALLCDW.-......H....GK..mQ..LSI.GSGLSLQEREH..........PPEIGQWI..TFKYYGLT..GSGK......PRFPVFMRIR.................
C0QLK9_DESAH/215-279                 ..........PGKGKNVGLMGAVKVRM.A......D....GK...E..FYI.GSGFTQEQRKN..........PPPVGSLV..TYRYQGFT..TTGI......PRFAVFVRL-.................
A1S744_SHEAM/214-279                 .........a-GKGQFEGMMGALHLRL.L......D....GR...E..FFL.GSGFSFDERRH..........PPAIGAWV..TFQYHGLT..DKGL......PKGARFLRVR.................
Q21YI4_RHOFT/230-295                 ..........PGRGRNQGRMGALLLEM.S......N....GQ...R..FAL.GTGFADAQRAD..........PPPVGSLV..TYRYRDRT..PKGL......PRFASFLRVR.................
W0DVL5_MARPU/229-294                 ..........PGKGRLRGMVGALLVED.A......E....GR...R..FRL.GSGLSDAERQA..........PPPVGSWV..TFRYQGYT..SNGI......PRFARYLRVR.................
R1D0P1_EMIHU/448-513                 ..........PGKGKHEGRLGALLCKL.R......S....GV...T..FKV.GTGFSDAERED..........PPPVGSVV..TFQYFELT..EARV......PRFPAYQRVR.................
D4ZLI4_SHEVD/217-282                 .........g-GKGKLAGVMGSLLVEN.H......Q....GV...R..FKL.GTGFSMKERKH..........PPEIGSTV..TYQYSGLT..QKGT......PRFARFLRVR.................
G2DI14_9NEIS/203-267                 ..........EGKGKYTGKLGAISCKN.-......Q....YG...E..FRI.GSGFKDADRSN..........PPPIGSTI..TYQYRGFT..QKGT......PRFATYLRRR.................
A0A0C5WEN3_9GAMM/234-299             ..........PGKGKYHGIMGAVWVTT.S......D....NR...K..FKI.GSGFSDHDRQY..........PPPLGSIV..QYRFNGYT..DSGL......PRFARFLRVR.................
Q15ZT3_PSEA6/211-275                 ..........PGNGKYQGMMGSIRVQM.S......N....GK...V..FKI.GSGFSDQERLS..........PPPIGAVI..TFKYYDLT..INGI......PKFASYIR--q................
A6VXW2_MARMS/210-275                 .........n-GSGKYDGMMGSVLVEM.P......S....GI...R..FKI.GSGFSDDERNT..........PPNIGDHV..IYKYHGFT..ERGI......PRFASFLRLR.................
C4ZII3_THASP/230-295                 ..........PGKGRLQGRVGALQVER.A......D....GR...R..FRI.GSGLSDALRAN..........PPALGALV..TYRYRELT..PAGL......PRFPRYLRER.................
C5KL83_PERM5/224-289                 .........q-GRGSDRG-ISSLVVVD.R......D....RT...I..FKL.GSGLTDEIRRD..........PPPVGTVI..QYKYSEIS.aLTGR......PRFPVYLRER.................
A0A067BFN0_SAPPC/451-515             ..........PGQGKHKGRTGSLKCVS.R......S....GK...S..FKV.GSGLNDKLREH..........PPAIGTII..TYRFQELT..AAGI......PRFPTYVGI-.................
V4JW06_9GAMM/240-305                 ..........PGKGKYTGMLGSLLVEE.P......D....GT...R..FRI.GTGFSDAERRN..........PPPVGSII..TFKYHGRT..SGGL......PRFASFLRIR.................
B7VNV5_VIBTL/224-289                 .........g-GTGKYKGMMGSILVHT.E......E....GV...E..FYI.GSGFSDQMRLA..........PPEIGSRI..TFRYNGFT..QNGK......PKFARFVR--ek...............
L0DG54_SINAD/274-339                 ..........KGAGRHKGRLGALLVEL.A......D....GT...R..FSV.GTGFSDAERSA..........PPAIGSTI..TFRYQELS..DSGV......PRFPSYVRVR.................
Q7UZI6_PROMP/357-435                 ..........EGTGRNEGRLGAILVEG.K......D....DQynyR..LNC.GSGFSDSQREEyw.....skkDKLIGQLV..EIRADART.qSQDAet..fsLRFPRFKCFR.................
A0A097QJT6_9VIBR/214-279             .........v-GKGKYSGQMGALLIQL.D......S....GI...E..FYI.GSGFTDEQRRQ..........PPKLGSII..TFRYNGYT..QNGI......PKFARYMRER.................
I5B6F4_9DELT/200-265                 ..........KGKGKYENAMGSLTLKL.E......N....GV...I..FKL.GTGFTDLIRNN..........PPAVGTTV..TFKYHGFS..KNAV......PKFASFLRVR.................
R9P4D2_PSEHS/762-826                 ..........EGTGRHAGRTGSLVARM.A......C....GT...V..FRV.GTGMSDAQRDN..........PPPIGSII..NYRFFELS..EDGY......PRFPAFRGV-.................
M9X4Q9_MANHA/203-267                 ..........KGKGKYTDKLGAITCEN.-......Q....RG...R..FRI.GSGFKDKEREN..........PPPIGSII..TYKYRGVT..ESGK......PRFATFWRIR.................
I4MH72_9BURK/212-277                 ..........PGKGRHAGRMGALVVQT.P......Q....GL...R..FKL.GTGFTDAERDQ..........PPAVGTWV..TYRFRGLN..ESGV......PRFASFVRVR.................
H5WI39_9BURK/222-287                 ..........PGRGRLAGQMGALRLRT.R......H....GV...E..FDL.GTGFTDAQRAA..........PPDVGAVV..SYTHRGFT..PAGV......PRFASFLRVR.................
K4E7Q5_TRYCR/409-479                 ..........EGRGKWKGCLGAFVCRT.K......R....GH...Q..FTV.APATTEQRKKDmw.....qrlAQYKGKML..TVQYQELS..ANGV......PRFPIGKCVR.................
F2UAM4_SALR5/583-648                 ..........PGKGRHKGAMGALEVEM.E......C....GK...K..FKI.GTGFSDAQRRS..........PPKVGAII..TYKFQELT..PDGI......PRFAAFVGER.................
Q7MKZ3_VIBVY/212-277                 ..........PGSGRLMGMLGALLVRL.D......D....GT...E..FYI.GSGFTDEQRKN..........PPAIGATV..TYRHNGFT..NSGK......PKFARYLRER.................
Q87PM4_VIBPA/212-277                 ..........PGTGRLLGMMGAMLVRL.P......D....GT...E..FYI.GSGFTDEVRRH..........PPKIGSTI..TFRYNGFT..QTGK......PRFARFLRER.................
Q47VW9_COLP3/224-289                 ..........EGKGKYQNQLGAIKVKT.S......D....GI...I..FKI.GSGLSDIQRAN..........PPKIGTII..TFKYNGLT..QAGI......PRFARFWRI-k................
A0A0B4XNV2_9GAMM/205-270             ..........PGKGRHAGRLGALQVET.A......E....GI...R..FRL.GTGFSDHERDV..........PPPLGSVV..TYRYHGVT..RDGV......PRFASFLRLR.................
K0CEZ9_ALCDB/216-281                 ..........PGEGKYTGMMGALLVKT.P......G....GR...H..FRL.GTGFSDGLRAR..........PPAIGSVV..TYKYHGHT..RHGL......PRFASFLRLR.................
B9TF49_RICCO/16-81                   ..........PGRGRLRGKLGALAVID.T......E....GR...R..FRV.GSGFTDAQRAS..........PPAVGALI..TYRFRERT..PRGL......PRFPVFVRER.................
A8H5J4_SHEPA/223-288                 .........s-GKGRFSGMMGALVVKN.Q......Q....GI...T..FNL.GTGFSKEQRQS..........PPQIGSLV..TYKYYGLT..QKGT......PRFASFLRVR.................
A0A0D1E8A3_USTMA/713-777             ..........EGTGKHEGRTGALVARM.A......C....GT...V..FRV.GTGMSDAQREQ..........PPPIGSII..NYRFFELS..EDGY......PRFPAFRG--i................
E6ZXQ4_SPORE/710-774                 .........d-GSGRHEGRTGSLVARM.A......C....GT...V..FRV.GTGMSDAQRDN..........PPPIGSII..NYRFFELS..EDGY......PRFPAFRGV-.................
Q0VKZ8_ALCBS/210-275                 .........a-GKGKYRGMMGALVVER.A......D....GR...Q..FKL.GTGFTDKQRKA..........PPPLGATV..TYKYFGKT..ATGL......PRFARFLRIR.................
A4G5U7_HERAR/224-289                 ..........PGKGKHQGRLGALLVEM.P......D....GQ...R..FRL.GTGFSDAQRTS..........PPVIGSWV..TYRYRDKN..RSGI......PRFASFMRVR.................
D1B3Z1_SULD5/203-268                 ..........KGEGKYKDVLGSLTCKN.D......V....GV...V..FKI.GSGFSDTQRHN..........PPAIGARI..TYKYKELT..KNGK......PRFPVFVRIR.................
A0C1A3_PARTE/348-413                 .........s-GMGKFKDQLGALKVQT.D......A....GI...T..FQI.GVGFNSKLRKD..........PPKIGSRV..SYSYYGLT..DDGK......PRFPVFERIR.................
B6V2K8_BPSP1/345-420                 .....egkeg---TQHEGSLGALIVEY.-......K....GN...T..VNV.GSGFSHQLRAElw.....ankEAQTDRII..EIEYKEET..TDKNgk..hsLREPRFKRFR.................
A0A0D2WMT9_CAPO3/496-561             ..........QGSGRHQGRLGALVCIL.A......D....GT...Q..FNC.GSGLSDQQRNK..........PPPIGSVV..IVRYQELT..AGKV......PRFPVFVGVR.................
A0A0A7EF20_9GAMM/207-272             .........a-GKGKYQGMVGALIVEL.K......S....GE...Q..IKL.GSGLSDALRKK..........PPVIGSQV..TYRYNGFT..KYGK......PRFARFLRVR.................
V3ZA01_LOTGI/425-490                 ..........PGTGRFHNAVGALLVEM.A......N....GK...Q..FHV.GSGLTDADRRK..........PPKKGTII..TYKFQEYT..NSGT......PRFPSYIGIR.................
D4KCE0_9FIRM/360-434                 ..........EGQNRLAGTMGALVVDY.-......K....GN...E..LRV.GSGFDDATRAAvw.....anpDNYIGKIV..ECKYKEVT..MDKKtg.lesLQFPTFVRFR.................
A1VNV0_POLNA/223-293                 ..........PGQGKYAGKLGALLVEM.Pa....aDg.kpAQ...R..FKL.GTGFSDAQRQN..........PPAVGTRI..TYRFRGLN..DSGI......PRFASFMRVR.................
U9U428_RHIID/450-514                 ..........PGKGKYLRQCGSLLCRM.A......S....GK...E..FKV.GSGMNDNDRIN..........PPSIGSII..IYKCQELS..NSGS......PRFPIYLGV-.................
G0ACU4_COLFT/226-290                 ..........PGKGKYQGMLGALLVET.P......D....GL...R..FKL.GSGFSDEQRRR..........PPALGSVV..TYRFRGLN..DSGI......PRFASFMRV-.................
A3QDA6_SHELP/202-267                 ..........EGKGKYRGMMGALEVET.N......E....GI...R..FKL.GTGFSDEQRRH..........PPAIGSTV..TYKYYGLT..HNGV......PRFASFMRVR.................
A2SFI2_METPP/223-287                 .........a-GKGRFVGQLGALRVRT.P......Q....GR...E..FAL.GTGFSDAQRAS..........PPPQGTVV..TYTYRGTT..ARGL......PRFASFLRM-.................
O41026_PBCV1/225-293                 .....sgkve------EDVMGSIEVDY.-......D....GV...V..FSI.GTGFDADQRRDfw.....qnkESYIGKMV..KFKYFEMG..SKDC......PRFPVFIGIR.................
#=GR O41026_PBCV1/225-293      SS    .....EEEEE------TTEEEEE-SS-.-......H....HH...E..EEE.-TTSSSS-EEEEE.....XXXXXXXXXXX..XXXXXXXX..XXXX......XXXXXXXXXX.................
D3G0Z1_BACPE/155-219                 ..........--NGVYAGMMELGIPSE.A......K....NV...F..YSI.ASQLITREKEN..........VVYIEPIIqcKVKYRNMT..SKGL......LRLPSFVEF-.................
V5EBF9_PSEBG/716-780                 ..........PGTGRHEGRTGSLVAQM.A......C....GT...T..FRV.GTGMSDAQRDN..........PPPIGTII..NYRFFELS..EDGY......PRFPAFRG--i................
A0RQQ3_CAMFF/199-265                 .........n-GKGKFEGLLGSLICVDiF......S....NI...E..FKI.GSGFSDEQRSN..........PPKVGTII..TYKYQNLT..KYAK......PRFPVFLRV-k................
Q4DIW6_TRYCC/443-513                 ..........PGQGKFRGGLGAFICET.K......T....GI...R..FNA.TPKTTYENRLAlw.....gkrQELLGKYL..TVQYQELS..SQDV......PRFPVAKAVR.................
Q6LIB5_PHOPR/225-290                 ..........EGNGKFDNKMGALWVVT.P......D....DI...T..FKI.GSGFKDFDREN..........PPAVGTTI..LFRYNGVT..NSGI......PRFARFIRIR.................
B8QU68_BPPPB/226-295                 ........ap------SGMVGAFVCRN.E......Vl.wpGV...T..FNVsASSLTHDEKKRlw.....ndrEHLKRQVI..RFKHFSHG..AKDK......PRHAVFDCW-.................
I7GTY9_9HELI/211-275                 ..........QGKGKYDSMLGAIICEY.-......N....GK...N..FKI.GSGLSDTLRHN..........PPPIGSII..SFKFQGLT..HNGT......PRFPTFWRI-k................
W0SK07_9RHOO/185-250                 ..........PGKGKYAGMLGALQMEL.P......D....GR...H..FAL.GSGLTDAQRRN..........PPSVGTQI..TYRYRELT..KNGM......PRFPRYLRVR.................
Q3SKL4_THIDA/238-303                 ..........PGKGKYAGMTGALRMET.P......D....GK...R..FRL.GSGLSDALRRQ..........PPPVGTRI..TYRYTALT..KNGM......PRFPRYLRVR.................
Q4Q960_LEIMA/549-621                 ..........EGSGKWKGFLGSFICVT.P.....dK....KH...R..FTV.TPASTDADKRRmwq....swkTVYKGKAL..TVQYQEIT..ADGV......PRFPVGKCVR.................
Q3IES5_PSEHT/212-277                 ..........PGKGKYQGMLGALRVKT.A......Q....GQ...L..FSI.GTGFSDAERES..........PPALGSTI..TYRFHGLT..KNGL......PRFASFLRVR.................
Q12AV7_POLSJ/231-301                 ..........PGKGKYVGVLGALLVEM.Pgv.dgkP....GR...R..FKL.GSGFNDEQRQN..........PPVLGSTV..TYRFRGLN..GSGV......PRFASFMRVR.................
H3HE25_PHYRM/185-249                 .........d-GKGKYVGMVGALRCRM.A......S....GK...M..FKV.ASGLSDAQRDK..........PPAVGSII..VYKCQELT..NDGI......PRFPVFVG--l................
Q4DMH8_TRYCC/409-479                 ..........EGRGKWKGCLGAFVCRT.K......R....GH...Q..FTV.APATTEQRKKDmw.....qrlAQYKGKML..TVQYQELS..ANGV......PRFPIGKCVR.................
G0QN32_ICHMG/641-706                 .........n-GTGRCQGMMGALLCEL.K......N....GI...Q..FKI.GSGFNDQQRKR..........PPKIGSIV..TFKYQNLS..KNGI......PRFPIFLRI-k................
A1KA91_AZOSB/230-295                 .........a-GKGRLAGVVGALEVEA.A......D....GR...R..FRL.GSGLDDAQRRA..........PPPVGSLV..TYRYRELT..GKGL......PRFPRFLRVR.................
DNLI_HAEIN/203-267                   ..........KGKGQFENVMGALTCKN.-......H....RG...E..FKI.GSGFNLNEREN..........PPPIGSVI..TYKYRGIT..NSGK......PRFATYWR--ek...............
A4HEZ0_LEIBR/398-468                 ..........PGEGKFKGALGAFICET.K......D....GK...L..FNT.PPKVPYKRRIElw.....ahrKEFLSKYL..TVQYQELS..SQNV......PRFPIAKAVR.................
D6XJX8_TRYB2/435-505                 ..........PGNGKFEGGLGAFVCET.S......T....GI...R..FNA.TPKTTTKRRLElw.....aerDRLLGKYL..TVQYQELS..SQDV......PRFPIAKCVR.................
A0A0D2VWS6_CAPO3/558-629             ...gsdveei--------ALAAVTIDY.-......E....GH...K..VNV.GSGFTNEQRRYfa.....khpEAILGKEI..TVRFSLES..TNKKgg..ksLRFPIFM---vl...............
I3YDC4_THIV6/241-306                 ..........PGQGKYAGMLGALLVED.A......N....GL...R..FRL.GTGFTDAERRA..........PPPLGSLV..TYKYLGYT..EKGI......PRFASFLRVR.................
I2G232_USTH4/727-791                 .........d-GSGRHEGRTGSLVARM.A......C....GT...V..FRV.GTGMSDAQRED..........PPPIGSII..NYRFFELS..EDGY......PRFPAFR---gl...............
U4LWK6_PYROM/338-408                 ..........QGQGKNANCTGALKVEM.Lsg.gkpT....GK...M..FKI.GTGLTDKQRRN..........PPKIGAIV..VYRYQELS..KSGT......PRFPSYAGER.................
Q1DEP0_MYXXD/283-348                 .........a-GAGRHKGRLGALEVEL.R......N....GT...R..FSV.GTGLSDAERAS..........PPPVGAII..TFRYQELS..NDGV......PRFPSYVGVR.................
Q233G4_TETTS/487-552                 .........r-GEGRCADMMGALVCRM.K......N....GK...E..FKI.GSGFNDDQRRR..........PPKKGSVI..TFKYQNLT..KDGK......PRFPIFLRI-k................
D5V319_ARCNC/200-262                 .......nyn------NKKMKSLTIKL.N......N....GI...I..FNL.GNGFSDKERLN..........PPKVGEQI..TFKYYDLT..KNGK......PKFASFLRIR.................
A0EC59_PARTE/331-396                 ..........EGTGRCQGMLGSLKVKN.T......S....GI...V..FNI.GSGLTDDIRQK..........PPKIGSRI..TYKYYGVS..KNNV......PRFPIYLRER.................
Q65U14_MANSM/182-246                 ..........KGKGQFANALGALTCKN.-......Q....RG...K..FRI.GSGFTLEDRVN..........PPAVGSVI..TYKYRGLT..KTGK......PRFATYWRKR.................
K3WC20_PYTUL/523-587                 .........d-GKGKYVGMTGALRCKM.A......S....GK...M..FKC.ASGLSDEQRAN..........PPKVGSII..VYKCQELT..NDGI......PRFPVFLGV-.................
Q9JXH4_NEIMB/207-271                 ..........EGKGRNAGRLGAVGCKN.-......R....HG...E..FRI.GSGFKDKDRDN..........PPKIGTLI..TYRYRGFT..RKGT......PKFATFVRVR.................
A8P6S5_COPC7/656-720                 ..........PGKGRNAGVTGALKCKM.A......S....GK...T..FNV.GTGLSDKQRKN..........PPKIGSII..VYRFQELT..RDKV......PRFPSFI---ge...............
#=GC SS_cons                         .....EEEEE------TTEEEEE-SS-.-......H....HH...E..EEE.-TTSSSS-EEEEE.....XXXXXXXXXXX..XXXXXXXX..XXXX......XXXXXXXXXX.................
#=GC seq_cons                        ...........GcG+apGhhGALhsch.t......s....Gp...p..Fpl.GoGhoDtpRps..........PPhlGohl..TY+YpslT..psGh......PRFssFhRlR.................
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