GenomeNet

Database: Pfam
Entry: DNA_pol3_tau_4
LinkDB: DNA_pol3_tau_4
Original site: DNA_pol3_tau_4 
#=GF ID   DNA_pol3_tau_4
#=GF AC   PF12168.6
#=GF DE   DNA polymerase III subunits tau domain IV DnaB-binding
#=GF AU   Assefa S, Bateman A, Coggill P
#=GF SE   PFAM-B_2296 (release 23.0)
#=GF GA   25.00 25.00;
#=GF TC   25.70 31.50;
#=GF NC   21.40 21.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   DNA_polymerase_III_holoenzyme
#=GF RN   [1]
#=GF RM   17355988
#=GF RT   The unstructured C-terminus of the tau subunit of Escherichia
#=GF RT   coli DNA polymerase III holoenzyme is the site of interaction
#=GF RT   with the alpha subunit.
#=GF RA   Jergic S, Ozawa K, Williams NK, Su XC, Scott DD, Hamdan SM,
#=GF RA   Crowther JA, Otting G, Dixon NE;
#=GF RL   Nucleic Acids Res. 2007;35:2813-2824.
#=GF DR   INTERPRO; IPR022001;
#=GF CC   This domain family is found in bacteria, and is approximately 80
#=GF CC   amino acids in length. The family is found in association with
#=GF CC   Pfam:PF00004. Domains I-III are shared between the tau and the
#=GF CC   gamma subunits, while most of the DnaB-binding Domain IV and all
#=GF CC   of the alpha-interacting Domain V are unique to tau.
#=GF SQ   80
#=GS A4W7F4_ENT38/415-497      AC A4W7F4.1
#=GS D2TLU7_CITRI/417-498      AC D2TLU7.1
#=GS I6H9H1_SHIFL/394-475      AC I6H9H1.1
#=GS V5AY97_ENTCL/417-498      AC V5AY97.1
#=GS Q7CK10_YERPE/431-512      AC Q7CK10.1
#=GS A0A0A2WL44_BEABA/417-497  AC A0A0A2WL44.1
#=GS C9P3P8_VIBME/441-529      AC C9P3P8.1
#=GS A0A0G4JPL8_9ENTR/456-538  AC A0A0G4JPL8.1
#=GS A0A0D8MSX1_PHOLE/487-576  AC A0A0D8MSX1.1
#=GS C5BCZ8_EDWI9/425-506      AC C5BCZ8.1
#=GS Q7MIV2_VIBVY/505-587      AC Q7MIV2.1
#=GS K8W0W5_9ENTR/417-499      AC K8W0W5.1
#=GS B4EU77_PROMH/426-512      AC B4EU77.1
#=GS A0A0C5W8L7_9GAMM/502-599  AC A0A0C5W8L7.1
#=GS A0A0A1B6Q5_9ENTR/426-504  AC A0A0A1B6Q5.1
#=GS W0LGG5_9ENTR/426-506      AC W0LGG5.1
#=GS A0A0M2K5H3_9ENTR/423-501  AC A0A0M2K5H3.1
#=GS A0A068ZDH1_9ENTR/416-496  AC A0A068ZDH1.1
#=GS Q6LTE8_PHOPR/512-610      AC Q6LTE8.1
#=GS W0HVW9_9ENTR/577-658      AC W0HVW9.1
#=GS F0LND5_VIBFN/476-557      AC F0LND5.1
#=GS D8MP18_ERWBE/421-499      AC D8MP18.1
#=GS J1QTB2_9ENTR/397-478      AC J1QTB2.1
#=GS DPO3X_SALTY/416-497       AC P74876.2
#=GS D4BYX7_PRORE/422-506      AC D4BYX7.1
#=GS Q5E464_VIBF1/481-565      AC Q5E464.1
#=GS K8W3R2_PRORE/417-501      AC K8W3R2.1
#=GS L0M962_ENTBF/416-498      AC L0M962.1
#=GS E3BGQ5_9VIBR/446-528      AC E3BGQ5.1
#=GS Q32J50_SHIDS/417-498      AC Q32J50.1
#=GS D4GLS6_PANAM/449-527      AC D4GLS6.1
#=GS F9TCD1_9VIBR/483-566      AC F9TCD1.1
#=GS A0A068QNN5_9ENTR/410-490  AC A0A068QNN5.1
#=GS A8GAU9_SERP5/424-504      AC A8GAU9.1
#=GS B7VL96_VIBTL/528-609      AC B7VL96.1
#=GS A0A0L0H3D6_9ENTR/417-499  AC A0A0L0H3D6.1
#=GS U3U447_9ENTR/1-41         AC U3U447.1
#=GS F7YLF7_VIBA7/483-566      AC F7YLF7.1
#=GS Q6D7Z9_PECAS/465-545      AC Q6D7Z9.1
#=GS H2IYX6_RAHAC/423-501      AC H2IYX6.1
#=GS Q2NV61_SODGM/507-588      AC Q2NV61.1
#=GS A0A0D8P829_9GAMM/485-577  AC A0A0D8P829.1
#=GS L0MDM2_SERMA/420-500      AC L0MDM2.1
#=GS C0AYK7_9ENTR/423-488      AC C0AYK7.1
#=GS A8T583_9VIBR/501-587      AC A8T583.1
#=GS A0A0F5AU55_9GAMM/519-611  AC A0A0F5AU55.1
#=GS A0A090TY53_9ENTR/415-496  AC A0A090TY53.1
#=GS A6D0M4_9VIBR/500-584      AC A6D0M4.1
#=GS D0YZ15_PHODD/462-554      AC D0YZ15.1
#=GS A0A0F5ZWL4_9GAMM/513-595  AC A0A0F5ZWL4.1
#=GS A6AR30_VIBCY/507-589      AC A6AR30.1
#=GS W8UAX0_YEREN/401-482      AC W8UAX0.1
#=GS Q9KT51_VIBCH/470-549      AC Q9KT51.1
#=GS I2BBM0_SHIBC/423-504      AC I2BBM0.1
#=GS J7U8B4_MORMO/414-496      AC J7U8B4.1
#=GS A0A089R7I4_PLUGE/413-494  AC A0A089R7I4.1
#=GS A0A0F4NJ03_9VIBR/484-566  AC A0A0F4NJ03.1
#=GS F9R8J0_VIBSN/495-578      AC F9R8J0.1
#=GS G7LLT4_9ENTR/428-509      AC G7LLT4.1
#=GS A0A089UPX0_9ENTR/417-497  AC A0A089UPX0.1
#=GS E6W9E7_PANSA/427-505      AC E6W9E7.1
#=GS B2VHV5_ERWT9/420-499      AC B2VHV5.1
#=GS A0A097R512_HAFAL/439-520  AC A0A097R512.1
#=GS A0A068R1Z7_9ENTR/433-513  AC A0A068R1Z7.1
#=GS A0A0G3QC10_KLUIN/420-501  AC A0A0G3QC10.1
#=GS DPO3X_ECOLI/417-498       AC P06710.1
#=GS Q7N0P0_PHOLL/432-512      AC Q7N0P0.1
#=GS U4K2V4_9VIBR/531-611      AC U4K2V4.1
#=GS A0A097QLX7_9VIBR/467-551  AC A0A097QLX7.1
#=GS D3VL65_XENNA/427-508      AC D3VL65.1
#=GS E0SDW7_DICD3/444-526      AC E0SDW7.1
#=GS I6H927_SHIFL/415-475      AC I6H927.1
#=GS A0A0A0Z277_9ENTR/433-510  AC A0A0A0Z277.1
#=GS Q87MQ2_VIBPA/490-568      AC Q87MQ2.1
#=GS E1SGE3_PANVC/466-544      AC E1SGE3.1
#=GS I0DRA1_PROSM/415-497      AC I0DRA1.1
#=GS A0A0F5VGY0_9GAMM/467-555  AC A0A0F5VGY0.1
#=GS A6T5N3_KLEP7/409-490      AC A6T5N3.1
#=GS D3V0A4_XENBS/431-512      AC D3V0A4.1
#=GS A8AJX3_CITK8/415-496      AC A8AJX3.1
A4W7F4_ENT38/415-497                 ...............NQLQR.AQ...GATKPKKSEPAAp.grARPV.nNAALERLA.............SVTERV......-QSRPA.S.....SAA.EV.K.-A.PAKK.EAYRWKSTN....TAV..EVKVEVA.TPKALK....
D2TLU7_CITRI/417-498                 ...............SQLQR.AQ...GATKAKKSEPAAa.trARPV.nNAALERLA.............SVTERV......-QARPA.P.....SAL.EQ.A.--.PAKK.EAYRWKATT....PVA..EVKKVVA.TPKALK....
I6H9H1_SHIFL/394-475                 ...............SQLQR.AQ...GATKPKKSEPAAa.srARPV.nNAALERLA.............SVSERV......-QARPA.V.....SAL.EK.-.-A.PAKK.EAYRWKATN....PVA..EVKEVVA.TPKALK....
V5AY97_ENTCL/417-498                 ..............r-QLQQ.AQ...GADKAKKSEPAAa.trARPV.sNAALERLA.............SVTERV......-QSRPA.A.....VTA.D-.-.NK.PVKK.EAYRWKATT....VVE..TVKEVIA.TPKALK....
Q7CK10_YERPE/431-512                 ...............TQLLR.QS...GTTTTKKNEPAAp.gkARPA..NSALERLA.............SVTERS......-QQRLA.A.....KTT.EE.-.KK.PAKK.EAYRWTAKN....QPE..VAAEPIA.TPKALR....
A0A0A2WL44_BEABA/417-497             ...............SQLMR.QQ...EADKAKKNEPAAq.rlARPA.kSSALERLA.............SVTERV......-QARPA.P.....SAL.E-.-.-K.PAKP.EAYRWKAQN....PTE..VAPEPVA.TPKALK....
C9P3P8_VIBME/441-529                 .....qlrsqrqglt-----.-P...KSTPVKKPDAVS....AKP-..TSILDRVA.............QRAQST.....sTPIPPN.E.....SLI.SH.Q.EP.TEQE.SVYQWRPSTstveSAS..QSTHNEL.TPTQIK....
A0A0G4JPL8_9ENTR/456-538             ...............SQLLR.KQ...GATPPKKAEPAAs.nsARPA..NSALERLA.............SVTERS......LQRRNA.Q.....DGA.S-.A.AA.KKKP.EAYRWRAQN....TVE..EVKADVA.TPKALR....
A0A0D8MSX1_PHOLE/487-576             ......rsqkrgqee-----.-M...PGQTVKKAPTTS....AKKV.tSSVLDRVA.............SKQKAMp...vsAQHVMP.T.....SNV.PT.Q.PQ.TVED.QEYRWKPTAk..pEHE..QQKKVDV.APRVLK....
C5BCZ8_EDWI9/425-506                 .........srlrqk-----.AA...GGSEPKKSEPAAl.qrAQPA..SSALERLA.............SISERG......-QQKIA.S.....AEQ.EQ.A.--.SARK.EAYRWKAQN....RPV..EKKAPKT.TPRALR....
Q7MIV2_VIBVY/505-587                 .....qlrsqrqgla-----.--...QNGGSKKSKAAS....AEK-..ESVLDRVA.............QKQATA......AQVSPR.Q.....SLA.PS.E.PE.VKED.EPYQWRPSQ....PVV..QSKSKEL.TPTEIK....
K8W0W5_9ENTR/417-499                 ..........eelks----S.QN...EDTNVKKHKPAAs.ekAKPA..MSALERLA.............AVTSSY......-QKSIE.N.....RAS.EP.-.KK.NAKP.KAYQWRPQS....EDT..IIKEVVT.TPKEIK....
B4EU77_PROMH/426-512                 .......rarqairg-----.AE...QETPPKKPQPATp.kqAKPA..ASALERLA.............AVSEKR......-QQRVN.E.....KRS.SV.A.VE.KKKK.EAYQWKPQN....PQA..QVTEPVVsSPKEIK....
A0A0C5W8L7_9GAMM/502-599             .......rskakrdg-----.-S...TSDSGKKAEPVR....AKKVasSSVLDRIAskq......ngqvQAAGNAmp.vpgALNTAA.A.....QPG.GM.E.NA.GAKA.AEYQWRPTT...lPEP..SEVQPVV.APTALK....
A0A0A1B6Q5_9ENTR/426-504             ...............TQLLR.QQ...GANKPKKSEPAAh..sARPA..GSALERLA.............QVTERA......-SKRPA.A.....ENT.A-.-.--.PVKK.EAYRWKAQN...tVVE..AEAPQVA.TPKALR....
W0LGG5_9ENTR/426-506                 ...............TQLLR.QQ...GASTPKKSEPAAp.gaARPV..NSALERLA.............SVTERS......-QKRQA.E.....KVV.A-.-.EK.PAKP.EAYRWRAQT....EPE..AVPEPLA.TPKALR....
A0A0M2K5H3_9ENTR/423-501             ...............TQLMR.QQ...GVTKPKKSEPAAq..gSQSA..GLALERLA.............AVGERG......-RKRQT.T.....PEP.--.-.AE.PVKK.EVYRWKSQS....AEA..EPEGVIA.TPKLLR....
A0A068ZDH1_9ENTR/416-496             ............rsq---LR.QQ...GASTAKKREPAAl.grARPA..SSALERLA.............SVTERS......-QQRQA.E.....KIV.PE.-.-K.PVKP.EAYRWRASS....EPE..VAPAVLT.TPKALR....
Q6LTE8_PHOPR/512-610                 ...............SQSKR.GN...EEQPVKKGEPAP....AKKV.aMNVLDRIAnkhagmrvpttgnTATNSAm....pASMIAT.Q.....ANG.TQ.A.NV.PEKK.DEYQWKPMQp..vAPE..EDTKLEV.APRKLK....
W0HVW9_9ENTR/577-658                 ..............t-ALLR.RQ...ESQKTKKAEPAPa..rQKAA..VSALERLA.............TVGERA......-QQRQP.A.....AGR.ED.S.VK.TPRP.EAYRWRASQ....QPE..AEPAPVT.TPKALR....
F0LND5_VIBFN/476-557                 ........rsqrqgl-----.AQ...KGTDPKKPEAAS....AKP-..VSVLERVA.............QRGQHA......AQMSPY.S.....APS.VD.D.--.TPDD.EAYQWRPTQn..lPTP..TQEKSEL.TPTQIK....
D8MP18_ERWBE/421-499                 ...............TQLMR.QQ...GATKPKKDEPAAq..rARPA..SSALERLA.............SVTERG......-QKRQL.A.....AEP.A-.-.-A.PVKE.EAYRWKAQT....QED..AIPEPVA.TPKALR....
J1QTB2_9ENTR/397-478                 ..............r-QLQR.AQ...GADKAKKSEPAAa.trARPV.sNAALERLA.............SVTERV......-QSRPA.P.....SAL.EQ.A.--.PAKK.EAYRWKATT....VVT..ETKEVVA.TPKALK....
DPO3X_SALTY/416-497                  ...............NQLQR.AQ...GVTKTKKSEPAAa.srARPV.nNSALERLA.............SVSERV......-QARPA.P.....SAL.ET.-.-A.PVKK.EAYRWKATT....PVV..QTKEVVA.TPKALK....
D4BYX7_PRORE/422-506                 ........rqalqsp-----.QS...EDPSPKKAKPVMp.erAKPA..ASALERLA.............AVTSKH......-QQNVV.N.....KAA.Q-.A.AK.PQKP.KQYQWKPQN...eEAM..APKEAIT.TPSEIK....
Q5E464_VIBF1/481-565                 .......lrsaknnl-----.TN...TGTGSKKASAAS....DKKK.tSSVLERIA.............EKQHLAp....rAQVSQI.G.....NSA.TQ.E.KK.PE--.EPYRWKSTQ....PEM..KKVVSDV.TPTKLK....
K8W3R2_PRORE/417-501                 ........rqalqsp-----.QS...EDPSPKKAKPVMp.erAKPA..ASALERLA.............AVTSKH......-QQNVE.N.....RAA.Q-.A.AK.PQKP.KQYQWKPQN...eESM..APKEAVT.TPSGIK....
L0M962_ENTBF/416-498                 ..............r-QLQQ.GN..aGAPKTKKSEPAAa.srARPV.nNAALERLA.............SVTERV......-SSRPA.P.....SAL.EK.-.-A.PAKK.EAYRWKSTL....PTQ..EVKVEVA.TPKALK....
E3BGQ5_9VIBR/446-528                 ........sqrkgls-----.SN...QGGETKKTEATS....VKS-..VSVLERLA.............QKHDTL......APVSPA.Q.....SDV.EV.L.PA.TEKD.EPYQWKPSR...vIAT..EEKVNPI.TPSLLK....
Q32J50_SHIDS/417-498                 ...............QQLQR.VQ...GATKAKKSEPAAa.tcARPV.nNAALERLA.............SVTDRV......-QARPV.P.....SAL.EK.-.-A.PAKK.EAYRWKATT....PVM..QQKEVVA.TPKALK....
D4GLS6_PANAM/449-527                 .............rt-QLLR.-Q...GANKAKKSEPAAp..gARPA..NSALERLA.............SVTERS......-QQRVR.D.....SAP.A-.-.-A.PVKK.EAYRWKAQT....PVT..EVAEPVA.TPKALR....
F9TCD1_9VIBR/483-566                 .....rsqrkglnpg-----.--...QGNTPKKANATS....AKP-..ESVLDRVA.............KKHGGS......AQVSPL.S.....QPNfNA.A.PE.PAKD.EPYQWKPTL....PQT..QKESIEL.TPTLLK....
A0A068QNN5_9ENTR/410-490             ............rnt--LTR.-Q...GNTPAKKPEPAEs.akAKPA..SSALERLV.............AVAE--......-QRPQS.Y.....LPE.TQ.E.PK.PVKK.EAYRWRATN....ARE..EKPRPTT.TPKAIK....
A8GAU9_SERP5/424-504                 ...............TQLLR.QQ...GASTTKKSEPAAp.gkARPA..NSALERLA.............SVTERS......-QQRQA.E.....KIV.Q-.-.EK.PAKP.EAYRWRALT....EPE..AEPEPLA.TPKALR....
B7VL96_VIBTL/528-609                 ..........rrssa---AT.DN...KGSTPKKAKATS....AKT-..-SVLDRVA.............QQHGGS......ERVSPA.S.....LSA.SS.T.EK.VTNDnEPYRWKPSK....PVV..KEVSKEL.TPTQIK....
A0A0L0H3D6_9ENTR/417-499             ...............SQLQR.TQ...GAPKPKKSEPAAa.prARPV.nNAALERLA.............SMSERV......-QSRPS.P.....SAL.ES.Q.-K.AVKK.EAYRWKATT....ITE..EVKEEVA.TPKALK....
U3U447_9ENTR/1-41                    .............mq-----.--...------------....----..--------.............------......-----Q.R.....ASE.PA.V.KA.PAKP.EAYRWKAQQ....QEE..SKPEPVA.TPKALR....
F7YLF7_VIBA7/483-566                 ........aqpakgv----N.ET...KSNGTKKPNAAS....TKS-..ESVLERVA.............SHGKSA......-RVSPL.S.....TSA.PE.A.AP.TLDN.EPYQWRPTLq..pVVV..EQQKTEL.TPTQIK....
Q6D7Z9_PECAS/465-545                 ...............SQLLR.KQ...GSTPPKKAEPAAs.dnTRPA..TSALERLA.............SVTERS......-IQRQN.A.....QTS.PS.-.-E.PKKP.EAYRWRAQN....KVD..EEKVDVT.TPKALR....
H2IYX6_RAHAC/423-501                 ..............t-QLLR.-Q...GSTTPKKAEPAAp.gkARPA..TSALERLA.............SVTERA......-Q-TLA.V.....KKE.P-.-.AA.PIKE.EAYRWKAMM....EPE..VAPEPVA.TPKALR....
Q2NV61_SODGM/507-588                 .............ta--LLK.RQ...ESQKTKKDEPAPa..lQKNA..VTALERLA.............TVGERA......HQRQPA.A.....GRA.EP.A.-K.TPRP.EEYRWRASQ....QPE..AAPEPVT.TPKALR....
A0A0D8P829_9GAMM/485-577             ..nqlrsqtkrgqeg-----.QT...AATSLKKPLTAP....AKKV.aTSVMDRIA.............NKQTAM......PSMKHN.A.....MPA.ST.AvDN.VTED.DEYRWKPMA....KPElnVEVKQEL.TPRVLK....
L0MDM2_SERMA/420-500                 ...............TQLQR.QQ...GASTAKKSEPAAp.grARPA..NSALERLA.............SVTERS......-QQRQA.E.....KIV.QQ.-.-K.PAKP.EAYRWRAQT....EPE..AAPEPVA.TPKALR....
C0AYK7_9ENTR/423-488                 ....aqllrarqaik----G.TE...QQTPPKKSEPATp.nrAKPA..ASALERLA.............AVSEKR......QQVVKR.Q.....TNA.PE.K.KE.K---.---------....---..-------.------rrv.
A8T583_9VIBR/501-587                 .qlrsqrqgqqqsaa-----.-A...PNGGPKKSNATS....AQK-..ESVIDRLA.............QLHGNS......AQVSPK.S.....APQ.AE.K.QA.PE-D.QAYRWRPTK....PVE..KKANTQL.TPTQLK....
A0A0F5AU55_9GAMM/519-611             ..........srmkr---QS.EQ...SGSGVKKAGRTP....AKTD.aLSVLDRVA.............TAAESAspvsapEQKTPS.V.....SLS.PV.T.EPtNGSS.EPYQWRSTQp..vSPE..PETVPSL.TPKSLK....
A0A090TY53_9ENTR/415-496             ...............SQLQR.AQ...GATKPKKSEPAAa.srARPV.nNAALERLA.............SVSERV......-QARPA.V.....SAL.EK.-.-A.PAKK.EAYRWKTTN....PVA..EVKEVVA.TPKALK....
A6D0M4_9VIBR/500-584                 .........qsasqg---QA.NS...GNSPVKKPKASS....ESA-..-SVLERVA.............QRTQGRt...psASNG-L.D.....AAK.SN.T.EQ.VKDN.EPYRWRPTG...nVVA..QEVKPVV.KPSTLK....
D0YZ15_PHODD/462-554                 nqlrsqtkrgqtppp-----.--...AGGEVKKSESAP....AKKV.aTSVLDRIA.............TKHNVGs...ntANAMPV.S.....NVE.TI.N.AK.DQEP.EEYQWKPML....NVA..QEQQSNI.ATKELK....
A0A0F5ZWL4_9GAMM/513-595             ...........rsrv----R.HQ...EGQSPKKGSAAT....AGGD.aLSVIDRIA.............AKHKPA......DPAVFQ.Q.....ASM.PN.E.NA.ATQD.EAYRWKPTK...iETA..EEKPVTV.TPDKIK....
A6AR30_VIBCY/507-589                 .........qgqqqq----Q.-QapgQSGGPKKSNATS....AQK-..ESVIDRLA.............QLHGNS......AQVSPK.S.....APQ.AE.K.QA.PE-D.EAYRWRPTK....PVE..KKANTQL.TPTQLK....
W8UAX0_YEREN/401-482                 ...............TQLLR.QS...GTTTAKKNEPAAp.gkARPA..NSTLERLA.............SVTERS......-QQRLA.A.....KST.EE.K.-K.PAKK.EAYRWTAQN....QPE..VAAEPVA.TPKALR....
Q9KT51_VIBCH/470-549                 .......lrskrqev-----.QN...KGADGKKSDATS....ATP-..ASALERIA.............QRAQQV......-QVSPE.R.....NDE.DE.L.-E.PE-E.EIYQWRPMQ....PIE..VAVKSEV.TPTQLK....
I2BBM0_SHIBC/423-504                 ..............s-QLNR.-Q...GGSRAKKSEPAAqgssARPV.aSSALERLA.............SFTDKV......-QSRPA.P.....SAL.EQ.A.--.PAKK.EAYRWKATT....KAE..TVPEVVA.TPKALK....
J7U8B4_MORMO/414-496                 ...........rdal----N.RQ...EIPPSKKSEPVTltekGKPA..NSALERLA.............AVTENR......-RGRAV.S.....APQ.P-.-.KA.SGKP.QPYQWRPQK....QDE.pEEKLPVA.RPKDIK....
A0A089R7I4_PLUGE/413-494             ...............SQLQR.AQ...GAPKAKKSEPAAa.srARPV.nNAALERLA.............SVTERV......-QSRPA.M.....AAA.QA.-.-Q.PKKK.EAYRWKATT....PVA..EVKEEVA.TPKALK....
A0A0F4NJ03_9VIBR/484-566             .......sqrkglnp-----.-T...PGNTPKKANAAS....VKP-..ESVLDRVA.............KKHSGS......AQVSPSlS.....ANI.AA.E.SE.LDKN.EPYQWKPTL....PQV..AKESIEL.TPTLLK....
F9R8J0_VIBSN/495-578                 ............sqr--SSA.SN...PGGEPKKASATS....AAKK..ESVLDRVA.............QKHAGS......AQVSSL.E.....NGL.PS.V.PV.EEQKdEAYRWKPTS...pQQI..KQEKKEL.TPTQIK....
G7LLT4_9ENTR/428-509                 ...............SQLLR.KQ...GATPPKKTEPAAl.nkTRPA..NSALERLA.............SVTELS......-MQRKS.A.....ADG.AS.A.-A.AKKP.EAYRWRAQN....KVE..DVKTDVA.TPKALR....
A0A089UPX0_9ENTR/417-497             ...............SQLMR.QQ...EADKAKKNEPAAq.rlARPA.kSSALERLA.............SVTERV......-QARPA.P.....TAL.E-.-.-K.PAKP.EAYRWKAQN....PIE..VAPEPVA.TPKALK....
E6W9E7_PANSA/427-505                 .............rt-QLLR.-Q...GASKAKKSEPAAr..sARPA..NTALERLA.............NVTERV......-QQRTT.E.....PAV.K-.-.-A.AAKP.EAYRWKAQT....PTE..VVAEPVA.TPKALR....
B2VHV5_ERWT9/420-499                 ...............TQLMR.HQ...GASKPKKSEPAAq..sARPA..GSALERLA.............AASERG......-QRRQQ.P.....SAT.E-.A.-T.PVKP.EAYRWKAQN....PIE..VKAEPCA.TPKALR....
A0A097R512_HAFAL/439-520             ..............s-QLRQ.KA..gGGTDPKKNEPAAp.vtARPA..SSALERLA.............SVTERS......-QQRQA.A.....AAE.A-.-.-K.PSKK.EAYRWKAQT...kAVE..AKREEIA.TPKALR....
A0A068R1Z7_9ENTR/433-513             ............kna---LN.RQ...GNTPLKKPEPAEs.akAKPV..SSALERLV.............AVAEQR......-PQSYL.P.....KAR.ES.-.-Q.PVKK.EAYRWRATQ....AGD..EKPRFTT.TPKAIK....
A0A0G3QC10_KLUIN/420-501             ..............r-QLQR.AQ...GADKTKKSEPAAa.arVRPV.nNSALERLA.............SVTERV......-QSRQA.P.....SAH.EE.A.--.AVKK.EAYRWKATT....VTE..EVKETVA.TPKALK....
DPO3X_ECOLI/417-498                  ...............QQLQR.VQ...GATKAKKSEPAAa.trARPV.nNAALERLA.............SVTDRV......-QARPV.P.....SAL.EK.-.-A.PAKK.EAYRWKATT....PVM..QQKEVVA.TPKALK....
Q7N0P0_PHOLL/432-512                 .............nv--LSR.QQ...EQTPTKKPESAMp.vkMKSA..TSALERLA.............AVSG--......-QRPQS.S.....IDK.KQ.E.NK.PEKK.EAYRWRAKN....IEE..KTETHVA.TPKALR....
U4K2V4_9VIBR/531-611                 ..........ggqns-----.KS...TSSSPKKVNAAP....AAKK..QSAAERIA.............QFAPAG......-QVSPA.S.....SAA.ATaE.KK.EVSN.EPYQWKPSK....PQV..KPQRTEL.TPTQIK....
A0A097QLX7_9VIBR/467-551             .........qlrsqr---KG.NN...QGNTPKKANATS....AKKS..DSVLDRVA.............QRHSGT......MPVSPL.S.....NSQ.SV.AtPE.PDKN.EPYQWKPTL....PQV..EKQGSEL.TPTQIK....
D3VL65_XENNA/427-508                 ............rds--LT-.RQ...GHTPPKKPEPAEs.akAKPA..SSALERLV.............AVAEQR......---PQS.Y.....LPK.TR.E.PK.SIKK.EAYRWRATH...vNTE..EKHTSVT.TPKAIK....
E0SDW7_DICD3/444-526                 ...............SQLLS.RQ...GNTPTKKTEPAAs.gkTRPV..NSALERLA.............SVTERG......-QQQMA.A.....KAV.AQ.E.-E.QKKQ.EAYRWRAQK...kAEP..VETAPVT.TPKALR....
I6H927_SHIFL/415-475                 ...............QQLQR.VQ...GATKAKKSEPAAa.trARPV.nNAALERLA.............SVTDRV......-QARPV.P.....SAL.EK.A.PA.KK--.---------....---..-------.------kria
A0A0A0Z277_9ENTR/433-510             .............rt-QLLR.-Q...GAGKVKKSEPAAr..pARPA..NQALERLA.............TVTERV......-QQRAP.E.....TAS.--.-.-A.PVKP.EAYRWKAQQ....QSE..EKAEPVA.TPKALR....
Q87MQ2_VIBPA/490-568                 .............qg--LQQnTT...QNGGTKKPKAAS....AKP-..ESVIDRVA.............QLHGNS......AQVSPN.S.....TPK.PT.E.--.PEVE.EAYRWRPSK....PVE..TKVNTKL.TPTQLK....
E1SGE3_PANVC/466-544                 .............rt-QLLR.-Q...GANKPKKSEPAAp..cARPA..NSALERLA.............SVTERS......-QQRIR.D.....REP.A-.-.-A.PVKE.EAYRWKAVN....QPV..EVAEPVA.TPKALR....
I0DRA1_PROSM/415-497                 ..........ealhs----S.QN...EGPDAKKNKPAAp.ekAKPA..MSALERLA.............AVTSQH......-QQNMA.S.....RAS.DV.K.-K.AAKP.KPYQWRPQS....EEA..NTKEAVT.TPTEIK....
A0A0F5VGY0_9GAMM/467-555             ...............SQSRR.GQ...ELAEPKKTEPAS...vKKPA..SSVLERIS.............NQHAGR.....rSQQAGM.NhgspvAEL.-P.A.TE.PAKA.EDYQWQPTSq..pEPE..IQAPAVI.APTELK....
A6T5N3_KLEP7/409-490                 ..............s-HLQR.SQ...GATTPKKSEPAAa.srARPV.nNAALERLS.............SITERV......-QARPA.A.....AAL.EQ.A.--.PAKK.EAYRWKATT....VVE..ETKVEVA.TPKALK....
D3V0A4_XENBS/431-512                 ............rhs---LT.RQ...GNTPPKKSEPAEp.vkAKSA..SSALERLA.............AVAEQR......---SQS.Y.....IPK.AQ.E.PK.PIKQ.EAYRWRTTN...tSIE..EKPVCVT.TPKAIK....
A8AJX3_CITK8/415-496                 ...............NQLQR.AQ...GATKTKKSEPAAa.srARPV.nNAALERLA.............SVSERV......-QARPA.P.....SAL.EQ.-.-T.PTKK.EAYRWKATN....PVV..EVKEVVA.TPKALK....
#=GC seq_cons                        ...................p.tQ...suspsKKuEPAu...tA+Ps..sSALERLA.............uVo-ps.......Qtpss.s.....sst.pt....t.PsKp.EAYRW+sps....ssp..pttpsls.TPKuLK....
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