GenomeNet

Database: Pfam
Entry: DNA_pol3_tau_4
LinkDB: DNA_pol3_tau_4
Original site: DNA_pol3_tau_4 
#=GF ID   DNA_pol3_tau_4
#=GF AC   PF12168.7
#=GF DE   DNA polymerase III subunits tau domain IV DnaB-binding
#=GF AU   Assefa S, Bateman A, Coggill P
#=GF SE   PFAM-B_2296 (release 23.0)
#=GF GA   25.00 25.00;
#=GF TC   25.10 26.00;
#=GF NC   20.80 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   DNA_polymerase_III_holoenzyme
#=GF RN   [1]
#=GF RM   17355988
#=GF RT   The unstructured C-terminus of the tau subunit of Escherichia
#=GF RT   coli DNA polymerase III holoenzyme is the site of interaction
#=GF RT   with the alpha subunit.
#=GF RA   Jergic S, Ozawa K, Williams NK, Su XC, Scott DD, Hamdan SM,
#=GF RA   Crowther JA, Otting G, Dixon NE;
#=GF RL   Nucleic Acids Res. 2007;35:2813-2824.
#=GF DR   INTERPRO; IPR022001;
#=GF CC   This domain family is found in bacteria, and is approximately 80
#=GF CC   amino acids in length. The family is found in association with
#=GF CC   Pfam:PF00004. Domains I-III are shared between the tau and the
#=GF CC   gamma subunits, while most of the DnaB-binding Domain IV and all
#=GF CC   of the alpha-interacting Domain V are unique to tau.
#=GF SQ   118
#=GS C4S7M2_YERMO/428-509      AC C4S7M2.1
#=GS E3BGQ5_9VIBR/445-528      AC E3BGQ5.1
#=GS A4W7F4_ENT38/415-497      AC A4W7F4.1
#=GS D4DW59_SEROD/427-507      AC D4DW59.1
#=GS D2TLU7_CITRI/417-498      AC D2TLU7.1
#=GS V5AY97_ENTCL/417-498      AC V5AY97.1
#=GS A0A0D8P829_9GAMM/489-577  AC A0A0D8P829.1
#=GS Q7CK10_YERPE/431-512      AC Q7CK10.1
#=GS A0A0H2M3Q1_PRORE/417-501  AC A0A0H2M3Q1.1
#=GS U3B7V0_VIBPR/489-568      AC U3B7V0.1
#=GS A0A0A2WL44_BEABA/417-497  AC A0A0A2WL44.1
#=GS K8WWH6_9GAMM/410-493      AC K8WWH6.1
#=GS W1IXQ6_9GAMM/427-508      AC W1IXQ6.1
#=GS A0A0J5P181_PLUGE/413-494  AC A0A0J5P181.1
#=GS R8AP49_PLESH/2-66         AC R8AP49.1
#=GS A0A0L7TG80_9GAMM/419-499  AC A0A0L7TG80.1
#=GS A0A0C5W8L7_9GAMM/503-599  AC A0A0C5W8L7.1
#=GS Q7MIV2_VIBVY/505-587      AC Q7MIV2.1
#=GS W1FWZ4_ECOLX/1-57         AC W1FWZ4.1
#=GS K8W0W5_9GAMM/417-499      AC K8W0W5.1
#=GS F7YLF7_VIBA7/482-566      AC F7YLF7.1
#=GS B4EU77_PROMH/426-512      AC B4EU77.1
#=GS A0A0G3CIB0_9GAMM/437-516  AC A0A0G3CIB0.1
#=GS A0A0V2F267_SALNE/1-46     AC A0A0V2F267.1
#=GS Q1ZP75_PHOAS/508-598      AC Q1ZP75.1
#=GS A0A090PN56_9VIBR/438-523  AC A0A090PN56.1
#=GS W1IRC1_9GAMM/429-507      AC W1IRC1.1
#=GS A0A0A1B6Q5_9GAMM/426-504  AC A0A0A1B6Q5.1
#=GS W0LGG5_9GAMM/426-506      AC W0LGG5.1
#=GS A0A0M2K5H3_9GAMM/423-501  AC A0A0M2K5H3.1
#=GS Q6LTE8_PHOPR/512-610      AC Q6LTE8.1
#=GS C5BCZ8_EDWI9/424-506      AC C5BCZ8.1
#=GS W0HVW9_9GAMM/577-658      AC W0HVW9.1
#=GS F0LND5_VIBFN/476-557      AC F0LND5.1
#=GS A0A085IK02_9ENTR/419-502  AC A0A085IK02.1
#=GS D8MP18_ERWBE/421-499      AC D8MP18.1
#=GS D4HY55_ERWAC/419-498      AC D4HY55.1
#=GS DPO3X_SALTY/416-497       AC P74876.2
#=GS A0A085HMK2_9GAMM/454-535  AC A0A085HMK2.1
#=GS V3TRM0_SERS3/445-527      AC V3TRM0.1
#=GS A0A0Q4MHY6_9GAMM/486-565  AC A0A0Q4MHY6.1
#=GS A0A0U5E7S5_9GAMM/426-505  AC A0A0U5E7S5.1
#=GS Q5E464_VIBF1/481-565      AC Q5E464.1
#=GS K8W3R2_PRORE/417-501      AC K8W3R2.1
#=GS A0A090SDP1_9VIBR/401-486  AC A0A090SDP1.1
#=GS A0A0J1GKN7_9GAMM/515-603  AC A0A0J1GKN7.1
#=GS A0A1B1KM73_SERPL/424-503  AC A0A1B1KM73.1
#=GS Q32J50_SHIDS/417-498      AC Q32J50.1
#=GS F9TCD1_9VIBR/483-566      AC F9TCD1.1
#=GS A0A068QNN5_9GAMM/410-490  AC A0A068QNN5.1
#=GS A8GAU9_SERP5/424-504      AC A8GAU9.1
#=GS A0A0W8JIA0_9VIBR/471-556  AC A0A0W8JIA0.1
#=GS A0A0L0H3D6_9ENTR/417-499  AC A0A0L0H3D6.1
#=GS I0QNR0_9GAMM/418-501      AC I0QNR0.1
#=GS E9CK69_9GAMM/416-496      AC E9CK69.1
#=GS A0A0B8PX55_9VIBR/458-538  AC A0A0B8PX55.1
#=GS U3U447_9ENTR/1-41         AC U3U447.1
#=GS A0A0J9BL85_9BACT/405-489  AC A0A0J9BL85.1
#=GS L8JEM9_9GAMM/509-597      AC L8JEM9.1
#=GS Q6D7Z9_PECAS/465-545      AC Q6D7Z9.1
#=GS C9P3P8_VIBME/442-529      AC C9P3P8.1
#=GS U3A4V9_9VIBR/480-565      AC U3A4V9.1
#=GS H2IYX6_RAHAC/423-501      AC H2IYX6.1
#=GS Q2NV61_SODGM/507-588      AC Q2NV61.1
#=GS A0A0J8VDT3_9GAMM/491-581  AC A0A0J8VDT3.1
#=GS L0MDM2_SERMA/420-500      AC L0MDM2.1
#=GS A0A071LV27_9ENTR/429-510  AC A0A071LV27.1
#=GS C0AYK7_9GAMM/423-488      AC C0AYK7.1
#=GS A0A0F7HCK1_SERFO/424-504  AC A0A0F7HCK1.1
#=GS A0A0F5AU55_9GAMM/519-611  AC A0A0F5AU55.1
#=GS A0A014MB93_9GAMM/421-498  AC A0A014MB93.1
#=GS A6D0M4_9VIBR/500-584      AC A6D0M4.1
#=GS A0A0F5ZWL4_9GAMM/513-595  AC A0A0F5ZWL4.1
#=GS E1SGE3_PANVC/465-544      AC E1SGE3.1
#=GS G5LK37_SALET/2-37         AC G5LK37.1
#=GS A0A084A5E6_9GAMM/429-509  AC A0A084A5E6.1
#=GS D0YZ15_PHODD/465-554      AC D0YZ15.1
#=GS W8UAX0_YEREN/401-482      AC W8UAX0.1
#=GS Q9KT51_VIBCH/470-549      AC Q9KT51.1
#=GS I2BBM0_SHIBC/423-504      AC I2BBM0.1
#=GS J7U8B4_MORMO/414-496      AC J7U8B4.1
#=GS A0A0J1JPZ6_9GAMM/536-630  AC A0A0J1JPZ6.1
#=GS F9R8J0_VIBSN/495-578      AC F9R8J0.1
#=GS T0P269_PHOTE/434-514      AC T0P269.1
#=GS G7LLT4_9GAMM/428-509      AC G7LLT4.1
#=GS A0A085JB51_9GAMM/420-505  AC A0A085JB51.1
#=GS A0A066RS12_9GAMM/477-564  AC A0A066RS12.1
#=GS A0A0B8NJC9_9VIBR/458-538  AC A0A0B8NJC9.1
#=GS E6W9E7_PANSA/427-505      AC E6W9E7.1
#=GS A0A089UPX0_9ENTR/417-497  AC A0A089UPX0.1
#=GS Q1Z5S3_9GAMM/518-616      AC Q1Z5S3.1
#=GS A0A097R512_HAFAL/439-520  AC A0A097R512.1
#=GS A0A068R1Z7_9GAMM/433-513  AC A0A068R1Z7.1
#=GS A0A0G3QC10_KLUIN/420-501  AC A0A0G3QC10.1
#=GS B7VL96_VIBTL/527-609      AC B7VL96.1
#=GS D4GLS6_PANAM/448-527      AC D4GLS6.1
#=GS Q7N0P0_PHOLL/432-512      AC Q7N0P0.1
#=GS DPO3X_ECOLI/417-498       AC P06710.1
#=GS A0A0M0IPP7_9VIBR/483-566  AC A0A0M0IPP7.1
#=GS U4K2V4_9VIBR/531-611      AC U4K2V4.1
#=GS A0A097QLX7_9VIBR/467-551  AC A0A097QLX7.1
#=GS A0A0N1KIS6_9GAMM/427-510  AC A0A0N1KIS6.1
#=GS A8T583_9VIBR/504-587      AC A8T583.1
#=GS D3VL65_XENNA/427-508      AC D3VL65.1
#=GS E0SDW7_DICD3/444-526      AC E0SDW7.1
#=GS A0A0C3I9A1_9VIBR/491-573  AC A0A0C3I9A1.1
#=GS U3CCA2_9VIBR/481-560      AC U3CCA2.1
#=GS J2XB20_KLEPN/409-490      AC J2XB20.1
#=GS A0A090V3C6_ESCVU/416-497  AC A0A090V3C6.1
#=GS Q87MQ2_VIBPA/490-568      AC Q87MQ2.1
#=GS A0A0F5VGY0_9GAMM/467-555  AC A0A0F5VGY0.1
#=GS A0A0J9B809_9BACT/420-500  AC A0A0J9B809.1
#=GS W6JC63_9ENTR/419-500      AC W6JC63.1
#=GS A6T5N3_KLEP7/409-490      AC A6T5N3.1
#=GS A0A0A5HS43_9VIBR/491-571  AC A0A0A5HS43.1
#=GS H5V6N5_ESCHE/420-501      AC H5V6N5.1
#=GS A8AJX3_CITK8/415-496      AC A8AJX3.1
#=GS D3V0A4_XENBS/431-512      AC D3V0A4.1
C4S7M2_YERMO/428-509                 ............TQLLR.QS.GTTTTKKSEPAAs.gkARPA..NSALERLA.............SVTERS..........-QQR.LAA....K.ST.E-.E...K..KPAKK.EAYRWVAQN....QPD..AVVEPVA.TPKALR....
E3BGQ5_9VIBR/445-528                 ....rsqrkgls-----.SN.QGGETKKTEATS....VKS-..VSVLERLA.............QKHDTL..........APVS.PAQ....S.DV.EV.L...P..ATEKD.EPYQWKPSR...vIAT..EEKVNPI.TPSLLK....
A4W7F4_ENT38/415-497                 ............NQLQR.AQ.GATKPKKSEPAAp.grARPV.nNAALERLA.............SVTERV..........-QSR.PAS....S.AA.EV.-...K..APAKK.EAYRWKSTN....TAV..EVKVEVA.TPKALK....
D4DW59_SEROD/427-507                 ............TQLQR.QQ.GASTPKKSEPAAp.grARPA..NSALERLA.............SVTERS..........-QQR.QAE....K.IV.K-.-...E..KPAKP.EAYRWRAQT....APE..AAPEPLA.TPKALR....
D2TLU7_CITRI/417-498                 ............SQLQR.AQ.GATKAKKSEPAAa.trARPV.nNAALERLA.............SVTERV..........-QAR.PAP....S.AL.EQ.A...-..-PAKK.EAYRWKATT....PVA..EVKKVVA.TPKALK....
V5AY97_ENTCL/417-498                 ...........r-QLQQ.AQ.GADKAKKSEPAAa.trARPV.sNAALERLA.............SVTERV..........-QSR.PAA....V.TA.D-.-...N..KPVKK.EAYRWKATT....VVE..TVKEVIA.TPKALK....
A0A0D8P829_9GAMM/489-577             ...sqtkrgqeg-----.QT.AATSLKKPLTAP....AKKV.aTSVMDRIA.............NKQTAM..........PSMK.HNA....M.PA.ST.A..vD..NVTED.DEYRWKPMA....KPElnVEVKQEL.TPRVLK....
Q7CK10_YERPE/431-512                 ............TQLLR.QS.GTTTTKKNEPAAp.gkARPA..NSALERLA.............SVTERS..........-QQR.LAA....K.TT.E-.E...K..KPAKK.EAYRWTAKN....QPE..VAAEPIA.TPKALR....
A0A0H2M3Q1_PRORE/417-501             .....rqalqsp-----.QS.EDPSPKKAKPVMp.erAKPA..ASALERLA.............AVTSKH..........-QQN.VEN....R.AS.G-.S...A..KPEKP.KQYQWKPQN...eAVM..NPKEAVT.TPTEIK....
U3B7V0_VIBPR/489-568                 ......pspdtk-----.--.AEPGVKKSSAAS....AKK-..ESVLDRVA.............QKHGTV..........-RMS.PAQ....L.AK.HA.Av.pQ..APAED.EPYQWKPAN....PVV..EVKKQEL.TPTEIK....
A0A0A2WL44_BEABA/417-497             ............SQLMR.QQ.EADKAKKNEPAAq.rlARPA.kSSALERLA.............SVTERV..........-QAR.PAP....S.AL.E-.-...-..KPAKP.EAYRWKAQN....PTE..VAPEPVA.TPKALK....
K8WWH6_9GAMM/410-493                 .....realqsp-----.QN.EGPDAKKNKPAMp.ekAKPA..VSALERLA.............AVTSQR..........--QK.NAA....N.SP.SE.A...K..KSAKP.KPYQWRPQF....EDT..EIKETKT.TPAGIK....
W1IXQ6_9GAMM/427-508                 .........rns--LTR.-Q.GNTPSKKPEPAEs.vkAKPA..SSALDRLL.............AVSEQR..........---P.QSY....I.PK.AR.E...P..EPVKK.EAYRWRAVN...nVEE..KKQQPVT.TPKSIK....
A0A0J5P181_PLUGE/413-494             ............SQLQR.AQ.GAPKAKKSEPAAa.srARPV.nNAALERLA.............SVTERV..........-QSR.PAA....A.AA.Q-.-...A..QPKKK.EAYRWKATT....PVA..EVKEEVA.TPKALK....
R8AP49_PLESH/2-66                    ..........lr-----.--.---------PAG....NKP-..-SPLERLA.............AAGEQR.........vRPVG.PRT....A.DS.AV.S...S..KAKKP.EAYRWKPVN....PVE..EAPE-VV.TPD---vvr.
A0A0L7TG80_9GAMM/419-499             ............TQLMR.QQ.GATKVKKSEPAAp..gARPA..SSALERLA.............SVTERG..........-QKR.QQA....A.AA.E-.A...G..ATVKK.EAYRWKALN....PVE..AKPEPVA.TPKALR....
A0A0C5W8L7_9GAMM/503-599             .....skakrdg-----.-S.TSDSGKKAEPVR....AKKVasSSVLDRIAskq......ngqvQAAGNAmp.....vpgALNT.AAA....Q.PG.GM.E...N..AGAKA.AEYQWRPTT...lPEP..SEVQPVV.APTALK....
Q7MIV2_VIBVY/505-587                 ...qlrsqrqgl-----.-A.QNGGSKKSKAAS....AEK-..ESVLDRVA.............QKQATA..........AQVS.PRQ....S.LA.PS.E...P..EVKED.EPYQWRPSQ....PVV..QSKSKEL.TPTEIK....
W1FWZ4_ECOLX/1-57                    ..........mn-----.--.------------....----..NAALERLA.............SVSERV..........-QAR.PAV....S.AL.E-.-...K..APAKK.EAYRWKATN....PVA..EVKEVVA.TPKALK....
K8W0W5_9GAMM/417-499                 .......eelks----S.QN.EDTNVKKHKPAAs.ekAKPA..MSALERLA.............AVTSSY..........-QKS.IEN....R.AS.E-.P...K..KNAKP.KAYQWRPQS....EDT..IIKEVVT.TPKEIK....
F7YLF7_VIBA7/482-566                 ....vaqpakgv----N.ET.KSNGTKKPNAAS....TKS-..ESVLERVA.............SHGKSA..........-RVS.PLS....T.SA.PE.A...A..PTLDN.EPYQWRPTLq..pVVV..EQQKTEL.TPTQIK....
B4EU77_PROMH/426-512                 ....rarqairg-----.AE.QETPPKKPQPATp.kqAKPA..ASALERLA.............AVSEKR..........-QQR.VNE....K.RS.SV.A...V..EKKKK.EAYQWKPQN....PQA..QVTEPVVsSPKEIK....
A0A0G3CIB0_9GAMM/437-516             ............NQLRR.QQ.GTSDAKKSDPATp.skVKPV..SSVLERLA.............SATEKS..........AGSR.PAK....A.PQ.A-.-...-..-PAKK.ESYRWKAQN....DFE..AVSEPVA.TPKALR....
A0A0V2F267_SALNE/1-46                ...........v-----.--.------------....----..--------.............--SERV..........-QAR.PAP....S.AL.E-.-...T..APVKK.EAYRWKATT....PVV..QTKEVVA.TPKALK....
Q1ZP75_PHOAS/508-598                 ...sqkqrghdd-----.-A.QASSVKKTSTTS....AKKV.aTSVLDRVA.............SKQKAMpt......saSRAM.PTS....N.LP.AE.Q...Q..QDKED.QEYRWKPTAk..pDAE..EAKKVDV.APRVLK....
A0A090PN56_9VIBR/438-523             ....rsqrtgqt-----.PT.GGNTPKKANATS....AAKK..ESVLDRVA.............QKHAGS..........AQVS.LHK....H.GL.PS.V...PvtEEKKD.DAYRWTPSA....PQI..KQEKNEL.TPTQIK....
W1IRC1_9GAMM/429-507                 .........rnm---LS.RQ.GNAPPKKAEPAAs.vkTKPA..SSALERLV.............TVAEQR..........---P.KSF....I.PE.VR.E...S..KPVKQ.EAYRWRAKN....IEE..KP--VTT.TPKAIK....
A0A0A1B6Q5_9GAMM/426-504             ............TQLLR.QQ.GANKPKKSEPAAh..sARPA..GSALERLA.............QVTERA..........-SKR.PAA....E.NT.A-.-...-..-PVKK.EAYRWKAQN...tVVE..AEAPQVA.TPKALR....
W0LGG5_9GAMM/426-506                 ............TQLLR.QQ.GASTPKKSEPAAp.gaARPV..NSALERLA.............SVTERS..........-QKR.QAE....K.VV.A-.-...E..KPAKP.EAYRWRAQT....EPE..AVPEPLA.TPKALR....
A0A0M2K5H3_9GAMM/423-501             ............TQLMR.QQ.GVTKPKKSEPAAq..gSQSA..GLALERLA.............AVGERG..........-RKR.QTT....P.EP.--.-...A..EPVKK.EVYRWKSQS....AEA..EPEGVIA.TPKLLR....
Q6LTE8_PHOPR/512-610                 ............SQSKR.GN.EEQPVKKGEPAP....AKKV.aMNVLDRIAnkhagmrvpttgnTATNSAm........pASMI.ATQ....A.NG.TQ.A...N..VPEKK.DEYQWKPMQp..vAPE..EDTKLEV.APRKLK....
C5BCZ8_EDWI9/424-506                 ......rsrlrq----K.AA.GGSEPKKSEPAAl.qrAQPA..SSALERLA.............SISERG..........-QQK.IAS....A.EQ.EQ.A...-..-SARK.EAYRWKAQN....RPV..EKKAPKT.TPRALR....
W0HVW9_9GAMM/577-658                 ...........t-ALLR.RQ.ESQKTKKAEPAPa..rQKAA..VSALERLA.............TVGERA..........-QQR.QPA....A.GR.ED.S...V..KTPRP.EAYRWRASQ....QPE..AEPAPVT.TPKALR....
F0LND5_VIBFN/476-557                 .....rsqrqgl-----.AQ.KGTDPKKPEAAS....AKP-..VSVLERVA.............QRGQHA..........AQMS.PYS....A.PS.VD.D...-..-TPDD.EAYQWRPTQn..lPTP..TQEKSEL.TPTQIK....
A0A085IK02_9ENTR/419-502             ...........r-QLQQ.SNpGVNTPKKSEPAAa.srARPV.nSAALERLA.............SVTERV..........-QAR.PEP....S.AL.T-.-...K..PAAKK.EAYRWKATT....PAE.eVKKEEIA.TPKALK....
D8MP18_ERWBE/421-499                 ............TQLMR.QQ.GATKPKKDEPAAq..rARPA..SSALERLA.............SVTERG..........-QKR.QLA....A.EP.A-.-...-..APVKE.EAYRWKAQT....QED..AIPEPVA.TPKALR....
D4HY55_ERWAC/419-498                 ............TQLMR.HQ.GASKSKKSEPAAq..sARPA..SSSLERLA.............AFSERG..........-QRR.QQQ....T.AG.E-.-...V..APIKQ.EAYRWKAQN....PTA..VKTEPRA.TPKALR....
DPO3X_SALTY/416-497                  ............NQLQR.AQ.GVTKTKKSEPAAa.srARPV.nNSALERLA.............SVSERV..........-QAR.PAP....S.AL.ET.-...-..APVKK.EAYRWKATT....PVV..QTKEVVA.TPKALK....
A0A085HMK2_9GAMM/454-535             ............SQLRR.QQ.ESSETKKSKPATp.agVKPA..SSVLERLA.............AATENK..........-GES.PTR....S.VK.SS.K...-..PEGKK.ESYRWKAQH....DFE..AVSQQVA.TPKALR....
V3TRM0_SERS3/445-527                 ............SQLLR.KQ.EATPPKKSEAAAf.skTRPV..TSALERLA.............SVAERG..........-QQQ.MSA....K.ET.A-.Q...P..EQKKQ.EAYRWRAQK....KIE.vVEKNVTT.TPKALR....
A0A0Q4MHY6_9GAMM/486-565             ............TQLLR.QQ.GANKAKKSEPAAq..sARPA..SSALERLA.............NVTERG..........-QQR.LQQ....A.AS.E-.-...A..APVKE.EAYRWKALT....PTE..IKAAPVA.TPKALR....
A0A0U5E7S5_9GAMM/426-505             ............TQLLR.QQ.GVSRPKKSEPAAp..vARPA..ISALERLA.............AVSERG..........---L.PRK....A.PA.AE.S...-..EPAKK.EAYRWTSQQ...kEQE..QVAEPVA.TPKALR....
Q5E464_VIBF1/481-565                 ....lrsaknnl-----.TN.TGTGSKKASAAS....DKKK.tSSVLERIA.............EKQHLAp........rAQVS.QIG....N.SA.TQ.E...K..KPE--.EPYRWKSTQ....PEM..KKVVSDV.TPTKLK....
K8W3R2_PRORE/417-501                 .....rqalqsp-----.QS.EDPSPKKAKPVMp.erAKPA..ASALERLA.............AVTSKH..........-QQN.VE-....N.RA.AQ.A...A..KPQKP.KQYQWKPQN...eESM..APKEAVT.TPSGIK....
A0A090SDP1_9VIBR/401-486             ....rqsagqnt----Q.PS.GTNPGKKPKASS....EP--..SSVLERVA.............MRTQGRaa......spTSVS.DVA....-.-E.TK.T...E..QANAN.EPYQWRPSS...nVAQ..QQSKPTI.KPSTLK....
A0A0J1GKN7_9GAMM/515-603             ........sqtk----RdGN.EPSHGKKAEPVQ....TKKV.aSSVLDRIA.............SKQNGSsft....ppaMSVP.GTS....G.AP.ST.S...D..TPATP.EEYQWRPTV....APQ..AGEAQAV.APTKLK....
A0A1B1KM73_SERPL/424-503             ...........t-QLLR.-Q.GASTPKKNEPAAp.gkARPA..NSALERLA.............SVTERS..........-QQR.LAE....K.QV.Q-.-...E..KPAKP.EAYRWRALT....EPE..PEPEPLA.TPKALR....
Q32J50_SHIDS/417-498                 ............QQLQR.VQ.GATKAKKSEPAAa.tcARPV.nNAALERLA.............SVTDRV..........-QAR.PVP....S.AL.E-.-...K..APAKK.EAYRWKATT....PVM..QQKEVVA.TPKALK....
F9TCD1_9VIBR/483-566                 ..rsqrkglnpg-----.--.QGNTPKKANATS....AKP-..ESVLDRVA.............KKHGGS..........AQVS.PLS....Q.PNfNA.A...P..EPAKD.EPYQWKPTL....PQT..QKESIEL.TPTLLK....
A0A068QNN5_9GAMM/410-490             .........rnt--LTR.-Q.GNTPAKKPEPAEs.akAKPA..SSALERLV.............AVAE--..........-QRP.QSY....L.PE.TQ.E...P..KPVKK.EAYRWRATN....ARE..EKPRPTT.TPKAIK....
A8GAU9_SERP5/424-504                 ............TQLLR.QQ.GASTTKKSEPAAp.gkARPA..NSALERLA.............SVTERS..........-QQR.QAE....K.IV.Q-.-...E..KPAKP.EAYRWRALT....EPE..AEPEPLA.TPKALR....
A0A0W8JIA0_9VIBR/471-556             .....rqsvqss---GS.ST.KGTPTKKSETAS....TKS-..DSVFDRLM.............QKRNDD.........lLMPS.DVD....S.QL.DA.E...T..AVDAA.EPYQWRPTI...eVPD..TPVDKSI.TPAALK....
A0A0L0H3D6_9ENTR/417-499             ............SQLQR.TQ.GAPKPKKSEPAAa.prARPV.nNAALERLA.............SMSERV..........-QSR.PSP....S.AL.ES.Q...-..KAVKK.EAYRWKATT....ITE..EVKEEVA.TPKALK....
I0QNR0_9GAMM/418-501                 ............TQLHR.QQ.GSSSPKKAEPAAp.gkAQPA..NTVLERLA.............SVTERS..........LERK.GAT....A.QK.KA.P...A..VPVKE.EAYRWKTVN....EPE..AAPEPVA.TPKALR....
E9CK69_9GAMM/416-496                 .........rsq---LR.QQ.GASTAKKREPAAl.grARPA..SSALERLA.............SVTERS..........-QQR.QAE....K.IV.P-.-...E..KPVKP.KAYRWRASS....EPE..VAPAVLT.TPKALR....
A0A0B8PX55_9VIBR/458-538             .....srrqqgg----Q.SE.GGNGAKKAETAQ....TKK-..DSVLARVT.............KKHPPS..........-APS.ESV....L.ST.--.P...N..EPVTP.QEYQWRPSQ...qKSN..ENETPSI.TPAMLK....
U3U447_9ENTR/1-41                    ..........mq-----.--.------------....----..--------.............------..........----.-QR....A.SE.PA.V...K..APAKP.EAYRWKAQQ....QEE..SKPEPVA.TPKALR....
A0A0J9BL85_9BACT/405-489             ....qllqarta--LMR.-Q.GASQAKKNEPVAs..sPRPA..QSALERLA.............TLTERK..........---A.PAA....G.QS.AS.A...K..AVEKK.ESYRWTSQR....TED..ATILPVA.TPKALR....
L8JEM9_9GAMM/509-597                 ...........s-QTKR.GNgEQSSVKKTESAP....AKKV.aTNVLDRIA.............SKHQDQ.........pAPVS.GAP....AmPA.PD.ApvmQ..ANTAV.EEYQWKPQA....RPE.iAEKKPEV.DPATLK....
Q6D7Z9_PECAS/465-545                 ............SQLLR.KQ.GSTPPKKAEPAAs.dnTRPA..TSALERLA.............SVTERS..........-IQR.QNA....Q.TS.P-.-...S..EPKKP.EAYRWRAQN....KVD..EEKVDVT.TPKALR....
C9P3P8_VIBME/442-529                 ...lrsqrqglt-----.-P.KSTPVKKPDAVS....AKP-..TSILDRVA.............QRAQST..........STPIpPNE....S.LI.SH.Q...E..PTEQE.SVYQWRPSTstveSAS..QSTHNEL.TPTQIK....
U3A4V9_9VIBR/480-565                 .sqrqgqqqpsv-----.--.ASGGPKKSRATS....AQK-..ESVIDRLS.............QLHSNT..........AQVS.PKL....N.SK.TE.N...TsaDEDED.EAYRWRPMK....PVE..QKPKVEL.TPTQIK....
H2IYX6_RAHAC/423-501                 ...........t-QLLR.-Q.GSTTPKKAEPAAp.gkARPA..TSALERLA.............SVTERA..........-QTL.AV-....K.KE.P-.-...A..APIKE.EAYRWKAMM....EPE..VAPEPVA.TPKALR....
Q2NV61_SODGM/507-588                 ..........ta--LLK.RQ.ESQKTKKDEPAPa..lQKNA..VTALERLA.............TVGERA..........HQRQ.PAA....G.RA.EP.A...-..KTPRP.EEYRWRASQ....QPE..AAPEPVT.TPKALR....
A0A0J8VDT3_9GAMM/491-581             ......lrsqkn-----.RA.ESPIGKKPESTP....AKKV.aTNVLDRIA.............TKAKNGhgqt..ampvSNAS.MPP....H.LV.A-.Q...Q..APLEP.EEYQWKSTQ...vVDV..SESKVKL.APRQIK....
L0MDM2_SERMA/420-500                 ............TQLQR.QQ.GASTAKKSEPAAp.grARPA..NSALERLA.............SVTERS..........-QQR.QAE....K.IV.QQ.-...-..KPAKP.EAYRWRAQT....EPE..AAPEPVA.TPKALR....
A0A071LV27_9ENTR/429-510             ............NQLQR.QQ.GDNPSKKREPAAs.grARPV.nTSALERLA.............AVTDRV..........-QAR.PAA....E.NA.A-.-...A..KPAKE.EAYRWKAQS....VPE..AAVEPVA.TPKALR....
C0AYK7_9GAMM/423-488                 ..aqllrarqai---KG.TE.QQTPPKKSEPATp.nrAKPA..ASALERLA.............AVSEKR..........QQVV.KRQ....T.NA.PE.K...K..EK---.---------....---..-------.------rrv.
A0A0F7HCK1_SERFO/424-504             ............TQLLR.QQ.GASTAKKNEPAAp.giARPA..NSALERLA.............SVTERS..........-QKR.QAE....K.IV.T-.-...E..KPAKP.EAYRWRALT....EPE..AAPEPLA.TPKALR....
A0A0F5AU55_9GAMM/519-611             .......srmkr---QS.EQ.SGSGVKKAGRTP....AKTD.aLSVLDRVA.............TAAESAspv....sapEQKT.PSV....S.LS.PVtE...P..TNGSS.EPYQWRSTQp..vSPE..PETVPSL.TPKSLK....
A0A014MB93_9GAMM/421-498             ...........t-QLLS.QQ.GATKPKKSEPAAq..gARSA..GSALERLA.............AVGERS..........-QKR.RPD....A.QS.--.-...A..EPLKK.EAYRWKAQT....A-E..VKPEPVA.TPKALR....
A6D0M4_9VIBR/500-584                 ......qsasqg---QA.NS.GNSPVKKPKASS....ESA-..-SVLERVA.............QRTQGRt.......psASNG.L-D....A.AK.SN.T...E..QVKDN.EPYRWRPTG...nVVA..QEVKPVV.KPSTLK....
A0A0F5ZWL4_9GAMM/513-595             ........rsrv----R.HQ.EGQSPKKGSAAT....AGGD.aLSVIDRIA.............AKHKPA..........DPAV.FQQ....A.SM.PN.E...N..AATQD.EAYRWKPTK...iETA..EEKPVTV.TPDKIK....
E1SGE3_PANVC/465-544                 .........art-QLLR.-Q.GANKPKKSEPAAp..cARPA..NSALERLA.............SVTERS..........-QQR.IRD....R.EP.A-.-...-..APVKE.EAYRWKAVN....QPV..EVAEPVA.TPKALR....
G5LK37_SALET/2-37                    ........xsal-----.--.------------....----..--------.............------..........----.---....-.--.--.E...T..APVKK.EAYRWKATT....PVV..QTKEVVA.TPKALK....
A0A084A5E6_9GAMM/429-509             ............TQLLR.QQ.GASTAKKSEPAAp.inGRPA..NSALERLA.............AVTERS..........-QQR.QAE....K.RV.A-.-...E..KPAKP.EAYRWRAQT....EPE..APQEPLA.TPKALR....
D0YZ15_PHODD/465-554                 rsqtkrgqtppp-----.--.AGGEVKKSESAP....AKKV.aTSVLDRIA.............TKHNVGs.......ntANAM.PVS....N.VE.TI.N...A..KDQEP.EEYQWKPML....NVA..QEQQSNI.ATKELK....
W8UAX0_YEREN/401-482                 ............TQLLR.QS.GTTTAKKNEPAAp.gkARPA..NSTLERLA.............SVTERS..........-QQR.LAA....K.ST.E-.E...K..KPAKK.EAYRWTAQN....QPE..VAAEPVA.TPKALR....
Q9KT51_VIBCH/470-549                 ....lrskrqev-----.QN.KGADGKKSDATS....ATP-..ASALERIA.............QRAQQV..........-QVS.PER....N.DE.DE.L...-..EPE-E.EIYQWRPMQ....PIE..VAVKSEV.TPTQLK....
I2BBM0_SHIBC/423-504                 ...........s-QLNR.-Q.GGSRAKKSEPAAqgssARPV.aSSALERLA.............SFTDKV..........-QSR.PAP....S.AL.EQ.A...-..-PAKK.EAYRWKATT....KAE..TVPEVVA.TPKALK....
J7U8B4_MORMO/414-496                 ........rdal----N.RQ.EIPPSKKSEPVTltekGKPA..NSALERLA.............AVTENR..........-RGR.AVS....A.PQ.P-.-...K..ASGKP.QPYQWRPQK....QDE.pEEKLPVA.RPKDIK....
A0A0J1JPZ6_9GAMM/536-630             ....sqvkrdga-----.--.APASGKKTQPVQ....AKKVatVSVLDRIA.............SKQNGRhaaapdampvPGMP.GGG....S.SS.QA.A...P..HSTAP.QEYQWRPTA...ePDE..SVVVTEV.APAQMK....
F9R8J0_VIBSN/495-578                 ........sqrs---SA.SN.PGGEPKKASATS....AAKK..ESVLDRVA.............QKHAGS..........AQVS.SLE....N.GL.PS.V...P..VEEQKdEAYRWKPTS...pQQI..KQEKKEL.TPTQIK....
T0P269_PHOTE/434-514                 ...........s-VLSR.QQ.EQTPPKKPKPATp.vkARPA..TSALERIA.............VVSG--..........-QRP.QSS....I.AK.TQ.E...E..KPEKK.EAYRWRAKN....IEE..KPETHVA.TPKALR....
G7LLT4_9GAMM/428-509                 ............SQLLR.KQ.GATPPKKTEPAAl.nkTRPA..NSALERLA.............SVTELS..........-MQR.KSA....A.DG.AS.A...-..AAKKP.EAYRWRAQN....KVE..DVKTDVA.TPKALR....
A0A085JB51_9GAMM/420-505             .....llqarte--LLR.-R.GASASKKTEPAVp..tAQPA..QSALERLA.............SVTDKV..........VRKT.PKE....S.GS.D-.A...G..NTARQ.ERYRWKTRQ....PET..TEAEPVA.TPKALR....
A0A066RS12_9GAMM/477-564             ...........s-KAKR.GQ.ESTEPKKAEPAS...vKKPA..TSVLDRISnqh.......asrRSQQTG..........QQTA.PVN....A.MQ.PS.Q...-..-PKPV.EEYQWQPVSq..pEVD..HQPEVVV.APTALK....
A0A0B8NJC9_9VIBR/458-538             .....srrqqgg----Q.SE.GGNGAKKAETAQ....TKK-..DSVLARVT.............KKHPPS..........-APS.ESV....L.ST.--.P...N..EPVTP.QEYQWRPSQ...qKSS..ENETPSI.TPAMLK....
E6W9E7_PANSA/427-505                 ..........rt-QLLR.-Q.GASKAKKSEPAAr..sARPA..NTALERLA.............NVTERV..........-QQR.TTE....P.AV.K-.-...-..AAAKP.EAYRWKAQT....PTE..VVAEPVA.TPKALR....
A0A089UPX0_9ENTR/417-497             ............SQLMR.QQ.EADKAKKNEPAAq.rlARPA.kSSALERLA.............SVTERV..........-QAR.PAP....T.AL.E-.-...-..KPAKP.EAYRWKAQN....PIE..VAPEPVA.TPKALK....
Q1Z5S3_9GAMM/518-616                 ............SQSKR.GN.EEHPVKKGEPAP....AKKV.aTNVLDRIAnkhagmrvpttgnTATNSAm........pASMI.ATQ....A.NG.TQ.A...N..VPEKK.DEYQWKPLQq..vVPE..EDTKLEV.APRKLK....
A0A097R512_HAFAL/439-520             ...........s-QLRQ.KAgGGTDPKKNEPAAp.vtARPA..SSALERLA.............SVTERS..........-QQR.QAA....A.AE.A-.-...-..KPSKK.EAYRWKAQT...kAVE..AKREEIA.TPKALR....
A0A068R1Z7_9GAMM/433-513             .........kna--L-N.RQ.GNTPLKKPEPAEs.akAKPV..SSALERLV.............AVAEQR..........-PQS.YLP....K.AR.E-.-...S..QPVKK.EAYRWRATQ....AGD..EKPRFTT.TPKAIK....
A0A0G3QC10_KLUIN/420-501             ...........r-QLQR.AQ.GADKTKKSEPAAa.arVRPV.nNSALERLA.............SVTERV..........-QSR.QAP....S.AH.EE.A...-..-AVKK.EAYRWKATT....VTE..EVKETVA.TPKALK....
B7VL96_VIBTL/527-609                 ......qrrssa---AT.DN.KGSTPKKAKATS....AK--..TSVLDRVA.............QQHGGS..........ERVS.PAS....L.SA.SS.T...E..KVTNDnEPYRWKPSK....PVV..KEVSKEL.TPTQIK....
D4GLS6_PANAM/448-527                 .........art-QLLR.-Q.GANKAKKSEPAAp..gARPA..NSALERLA.............SVTERS..........-QQR.VRD....S.AP.A-.-...-..APVKK.EAYRWKAQT....PVT..EVAEPVA.TPKALR....
Q7N0P0_PHOLL/432-512                 ..........nv--LSR.QQ.EQTPTKKPESAMp.vkMKSA..TSALERLA.............AVSG--..........-QRP.QSS....I.DK.KQ.E...N..KPEKK.EAYRWRAKN....IEE..KTETHVA.TPKALR....
DPO3X_ECOLI/417-498                  ............QQLQR.VQ.GATKAKKSEPAAa.trARPV.nNAALERLA.............SVTDRV..........-QAR.PVP....S.AL.E-.-...K..APAKK.EAYRWKATT....PVM..QQKEVVA.TPKALK....
A0A0M0IPP7_9VIBR/483-566             ...rsqrkginp-----.-T.QGNLPKKANATS....AKS-..ESVLDRVA.............KKHAGA..........GQVS.PLS....S.HN.PNvA...P..EPAKN.EPYQWKPIL....PQA..KKETLEL.TPTLLK....
U4K2V4_9VIBR/531-611                 .......ggqns-----.KS.TSSSPKKVNAAP....AAKK..QSAAERIA.............QFAPAG..........-QVS.PAS....S.AA.AT.A...E.kKEVSN.EPYQWKPSK....PQV..KPQRTEL.TPTQIK....
A0A097QLX7_9VIBR/467-551             ......qlrsqr---KG.NN.QGNTPKKANATS....AKKS..DSVLDRVA.............QRHSGT..........MPVS.PLS....N.SQ.SV.A..tP..EPDKN.EPYQWKPTL....PQV..EKQGSEL.TPTQIK....
A0A0N1KIS6_9GAMM/427-510             ....rqslqmpp-----.-D.EGSASKKDKPAKp..qAKPA..MSALERLA.............AVSTQR..........QQNA.QKK....N.TE.QP.Q...N..KPEKP.VPYQWRSQN....KQI..AEPQVTT.T-----aeik
A8T583_9VIBR/504-587                 .sqrqgqqqsaa-----.-A.PNGGPKKSNATS....AQK-..ESVIDRLA.............QLHGNS..........AQVS.PKS....A.PQ.AE.K...Q..APE-D.QAYRWRPTK....PVE..KKANTQL.TPTQLK....
D3VL65_XENNA/427-508                 .........rds--LTR.-Q.GHTPPKKPEPAEs.akAKPA..SSALERLV.............AVAE--..........-QRP.QSY....L.PK.TR.E...P..KSIKK.EAYRWRATH...vNTE..EKHTSVT.TPKAIK....
E0SDW7_DICD3/444-526                 ............SQLLS.RQ.GNTPTKKTEPAAs.gkTRPV..NSALERLA.............SVTERG..........-QQQ.MAA....K.AV.AQ.E...-..EQKKQ.EAYRWRAQK....KAE.pVETAPVT.TPKALR....
A0A0C3I9A1_9VIBR/491-573             .qqsgaqtestp-----.-Q.QSGGSKKPKAAS....AQP-..ESVIDRLA.............QLHGNS..........AQVS.PKV....S.PN.KE.E...P..VVE--.EAYRWRPSK....VAE..TKVNTQL.TPTQLK....
U3CCA2_9VIBR/481-560                 .....krqskss-----.IQ.GDSNVKKGEATP....TGKK..ESVLQRVT.............QQHPPK..........---A.PSQ....S.VL.QQ.Q...-..VDTSN.QPYQWQASE...tFQP..EEKKPSL.TPALLK....
J2XB20_KLEPN/409-490                 ............SHLQR.SQ.GATTPKKSEPAAa.srARPV.nNAALERLS.............SITERV..........-QAR.PAA....A.AL.EQ.A...-..-PAKK.EAYRWKATT....VVE..ESKVEVA.TPKALK....
A0A090V3C6_ESCVU/416-497             ............SQLQR.AQ.GATKAKKSEPAAa.trTRPV.nNAALERLA.............SVTERI..........-QTR.PAA....A.AQ.EQ.A...-..-PVKK.EAYRWKTTL....VTE..EVKEVVA.TPKALK....
Q87MQ2_VIBPA/490-568                 ..........qg--LQQnTT.QNGGTKKPKAAS....AKP-..ESVIDRVA.............QLHGNS..........AQVS.PNS....T.PK.PT.E...-..-PEVE.EAYRWRPSK....PVE..TKVNTKL.TPTQLK....
A0A0F5VGY0_9GAMM/467-555             ............SQSRR.GQ.ELAEPKKTEPAS...vKKPA..SSVLERIS.............NQHAGRr........sQQAG.MNHgspvA.EL.P-.A...T..EPAKA.EDYQWQPTSq..pEPE..IQAPAVI.APTELK....
A0A0J9B809_9BACT/420-500             ............TQLLR.HQ.GASKPKKSEPAAq..gARPA..SSALERLA.............AVTERG..........-QQR.LQQ....A.AA.QP.A...-..APVKE.EAYRWKALN....PTE..VKTEKVA.TPKALR....
W6JC63_9ENTR/419-500                 ...........r-QLQR.AQ.GADKAKKSEPAAa.trARPV.sNAALERLA.............SVTERV..........-QSR.PAP....S.AL.EQ.A...-..-PAKK.EAYRWKATT....VVE..TVKEVVA.TPKALK....
A6T5N3_KLEP7/409-490                 ............SHLQR.SQ.GATTPKKSEPAAa.srARPV.nNAALERLS.............SITERV..........-QAR.PAA....A.AL.EQ.A...-..-PAKK.EAYRWKATT....VVE..ETKVEVA.TPKALK....
A0A0A5HS43_9VIBR/491-571             ....gltpnpda-----.--.SGNAPKKARATS....AKP-..DSVLDRVA.............QKHGGA..........SQVS.PLS....N.PQ.ST.A...T..PVEEN.EPYRWKPTL....PQK..EQQKTEL.TPTQLK....
H5V6N5_ESCHE/420-501                 ...........s-RLQK.AQ.EGSRTKKSEPAAp.ktARPV.sNSALERLA.............SVTERV..........-KAK.PAS....T.LK.ES.-...-..TPAKP.EAYRWKAQN....VVE..VAPEPVA.TPKALK....
A8AJX3_CITK8/415-496                 ............NQLQR.AQ.GATKTKKSEPAAa.srARPV.nNAALERLA.............SVSERV..........-QAR.PAP....S.AL.EQ.T...-..-PTKK.EAYRWKATN....PVV..EVKEVVA.TPKALK....
D3V0A4_XENBS/431-512                 .........rhs---LT.RQ.GNTPPKKSEPAEp.vkAKSA..SSALERLA.............AVAE--..........-QRS.QSY....I.PK.AQ.E...P..KPIKQ.EAYRWRTTN...tSIE..EKPVCVT.TPKAIK....
#=GC seq_cons                        ................p.tp.susssKKuEPAu....A+Ps..sSALERLA.............uls-ps...........Qtp..ss....s.st.t..t......tPsKp.EAYRW+sps....ssc..pttcsls.TPKuLK....
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