GenomeNet

Database: Pfam
Entry: DUF128
LinkDB: DUF128
Original site: DUF128 
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#=GF ID   DUF128
#=GF AC   PF01995.11
#=GF DE   Domain of unknown function DUF128
#=GF AU   Enright A, Ouzounis C, Bateman A
#=GF SE   Enright A
#=GF GA   25.00 25.00;
#=GF TC   63.90 27.70;
#=GF NC   22.10 23.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR002846;
#=GF CC   This archaebacterial protein family has no known function. The
#=GF CC   domain is found duplicated in Swiss:O27611. Many of these are
#=GF CC   attached to an N-terminal winged helix domain suggesting these
#=GF CC   are transcriptional regulators and that this domain has a ligand
#=GF CC   binding function.
#=GF SQ   122
#=GS D7E9U3_METEZ/85-324   AC D7E9U3.1
#=GS O28056_ARCFU/83-322   AC O28056.1
#=GS Q6LZL7_METMP/81-300   AC Q6LZL7.1
#=GS Q3ZXS5_DEHSC/100-340  AC Q3ZXS5.1
#=GS D3E025_METRM/83-314   AC D3E025.1
#=GS D3S704_METSF/319-536  AC D3S704.1
#=GS Q0W3T7_UNCMA/85-325   AC Q0W3T7.1
#=GS F0T764_METSL/84-315   AC F0T764.1
#=GS D2BI12_DEHSV/100-340  AC D2BI12.1
#=GS C7P654_METFA/83-303   AC C7P654.1
#=GS D3S704_METSF/83-303   AC D3S704.1
#=GS Q12VH9_METBU/85-324   AC Q12VH9.1
#=GS C7P654_METFA/319-536  AC C7P654.1
#=GS F6D855_METSW/84-315   AC F6D855.1
#=GS Y159_METJA/86-306     AC Q57623.1
#=GS B9AG53_METSM/331-559  AC B9AG53.1
#=GS D5EGZ4_AMICL/87-327   AC D5EGZ4.1
#=GS Q3Z7W5_DEHE1/100-340  AC Q3Z7W5.1
#=GS F8AN19_METOI/322-537  AC F8AN19.1
#=GS D9PU67_METTM/328-557  AC D9PU67.1
#=GS Q58GH9_METVO/372-598  AC Q58GH9.1
#=GS G6FK99_9EURY/5-245    AC G6FK99.1
#=GS D8K457_DEHLB/90-330   AC D8K457.1
#=GS E1QIV0_DESB2/84-324   AC E1QIV0.1
#=GS D2ZNH3_METSM/83-312   AC D2ZNH3.1
#=GS F8AN19_METOI/84-306   AC F8AN19.1
#=GS A6UTI8_META3/327-542  AC A6UTI8.1
#=GS D1YUP9_METPS/8-248    AC D1YUP9.1
#=GS F7XQB9_METZD/8-248    AC F7XQB9.1
#=GS G7WN74_METH6/89-329   AC G7WN74.1
#=GS A9A6B8_METM6/316-533  AC A9A6B8.1
#=GS Q8TYG2_METKA/85-324   AC Q8TYG2.1
#=GS A7I5N3_METB6/83-315   AC A7I5N3.1
#=GS D3L1C4_9BACT/91-331   AC D3L1C4.1
#=GS Q2FSW2_METHJ/5-245    AC Q2FSW2.1
#=GS D3RXS6_FERPA/85-323   AC D3RXS6.1
#=GS H1YYZ9_9EURY/85-316   AC H1YYZ9.1
#=GS Q46DJ8_METBF/85-323   AC Q46DJ8.1
#=GS Q46BP9_METBF/8-248    AC Q46BP9.1
#=GS G6FHR9_9EURY/83-314   AC G6FHR9.1
#=GS G7WQV7_METH6/7-237    AC G7WQV7.1
#=GS B8GJM0_METPE/83-314   AC B8GJM0.1
#=GS Q8THV7_METAC/119-358  AC Q8THV7.1
#=GS F6D855_METSW/333-564  AC F6D855.1
#=GS D7DT16_METV3/364-581  AC D7DT16.1
#=GS D1YVU6_METPS/85-325   AC D1YVU6.1
#=GS H8IAG6_METCZ/85-325   AC H8IAG6.1
#=GS Q8PXY1_METMA/85-323   AC Q8PXY1.1
#=GS G0H4D6_METMI/81-300   AC G0H4D6.1
#=GS E3GY38_METFV/326-554  AC E3GY38.1
#=GS F6BCA0_METIK/84-304   AC F6BCA0.1
#=GS Q8J2Z0_METMI/316-533  AC Q8J2Z0.1
#=GS Q0W777_UNCMA/8-248    AC Q0W777.1
#=GS Q2NHI2_METST/78-305   AC Q2NHI2.1
#=GS E1RE52_METP4/108-338  AC E1RE52.1
#=GS A0B970_METTP/33-263   AC A0B970.1
#=GS C9RDX5_METVM/319-536  AC C9RDX5.1
#=GS Q58GH8_METTL/84-304   AC Q58GH8.1
#=GS Y159_METJA/322-539    AC Q57623.1
#=GS Y159_METJA/322-539    DR PDB; 3NEK B; 322-539;
#=GS Y159_METJA/322-539    DR PDB; 3NEK A; 322-539;
#=GS F0T764_METSL/333-564  AC F0T764.1
#=GS A6USA1_METVS/81-300   AC A6USA1.1
#=GS A6USA1_METVS/316-533  AC A6USA1.1
#=GS Q8J2Z0_METMI/81-300   AC Q8J2Z0.1
#=GS C9RDX5_METVM/83-303   AC C9RDX5.1
#=GS D7DT16_METV3/81-312   AC D7DT16.1
#=GS D2ZNH3_METSM/331-559  AC D2ZNH3.1
#=GS B5YAL2_DICT6/84-326   AC B5YAL2.1
#=GS O27611_METTH/88-314   AC O27611.1
#=GS D5E812_METMS/8-248    AC D5E812.1
#=GS G2MN03_9ARCH/87-270   AC G2MN03.1
#=GS H1YZ00_9EURY/6-246    AC H1YZ00.1
#=GS Q58GH9_METVO/81-322   AC Q58GH9.1
#=GS B9AG53_METSM/83-312   AC B9AG53.1
#=GS A7IAT0_METB6/5-245    AC A7IAT0.1
#=GS A4FYM1_METM5/316-533  AC A4FYM1.1
#=GS B8E0N2_DICTD/84-326   AC B8E0N2.1
#=GS B8GHD6_METPE/5-245    AC B8GHD6.1
#=GS A4FYM1_METM5/81-300   AC A4FYM1.1
#=GS H1KZJ0_9EURY/84-304   AC H1KZJ0.1
#=GS H1KZJ0_9EURY/320-537  AC H1KZJ0.1
#=GS F4BZP9_METCG/89-329   AC F4BZP9.1
#=GS Q2FTS7_METHJ/83-316   AC Q2FTS7.1
#=GS H3ZNZ7_THELI/85-326   AC H3ZNZ7.1
#=GS Q8TSH4_METAC/8-248    AC Q8TSH4.1
#=GS Q6LZL7_METMP/316-533  AC Q6LZL7.1
#=GS A5FQT6_DEHSB/100-340  AC A5FQT6.1
#=GS A3CSY8_METMJ/86-318   AC A3CSY8.1
#=GS E3GY38_METFV/84-308   AC E3GY38.1
#=GS D7EBR2_METEZ/12-252   AC D7EBR2.1
#=GS F6BCA0_METIK/320-537  AC F6BCA0.1
#=GS A6UTI8_META3/83-311   AC A6UTI8.1
#=GS Q2LQG6_SYNAS/84-324   AC Q2LQG6.1
#=GS G0H4D6_METMI/316-533  AC G0H4D6.1
#=GS O27611_METTH/332-561  AC O27611.1
#=GS D9PU67_METTM/84-310   AC D9PU67.1
#=GS A6VJR1_METM7/81-300   AC A6VJR1.1
#=GS A0B6Y5_METTP/84-309   AC A0B6Y5.1
#=GS Q58GH8_METTL/320-538  AC Q58GH8.1
#=GS A5UN44_METS3/83-312   AC A5UN44.1
#=GS C6A4T1_THESM/104-345  AC C6A4T1.1
#=GS F4BX01_METCG/4-234    AC F4BX01.1
#=GS F8F2H0_SPICH/85-325   AC F8F2H0.1
#=GS A5UN44_METS3/331-559  AC A5UN44.1
#=GS H8I6V2_METCZ/8-248    AC H8I6V2.1
#=GS D5VS72_METIM/82-300   AC D5VS72.1
#=GS A9A6B8_METM6/81-300   AC A9A6B8.1
#=GS D5E8G5_METMS/85-321   AC D5E8G5.1
#=GS A3CSS1_METMJ/5-245    AC A3CSS1.1
#=GS Q12VW5_METBU/8-248    AC Q12VW5.1
#=GS Q8PVJ4_METMA/8-248    AC Q8PVJ4.1
#=GS Q2NHI2_METST/324-553  AC Q2NHI2.1
#=GS E1RE54_METP4/5-245    AC E1RE54.1
#=GS D3E025_METRM/333-561  AC D3E025.1
#=GS D3SUV1_NATMM/83-191   AC D3SUV1.1
#=GS D3S1I8_FERPA/83-324   AC D3S1I8.1
#=GS A6VJR1_METM7/316-533  AC A6VJR1.1
#=GS F7XPA1_METZD/85-324   AC F7XPA1.1
#=GS D3SUV6_NATMM/199-332  AC D3SUV6.1
#=GS D5VS72_METIM/316-533  AC D5VS72.1
#=GS D3SJ14_DEHSG/90-330   AC D3SJ14.1
#=GS B5YGF1_THEYD/80-318   AC B5YGF1.1
#=GS D3SUV6_NATMM/83-195   AC D3SUV6.1
D7E9U3_METEZ/85-324              ............LSFVSTRIEELMYRMNFDPETEEGNVIVNISLVD..............NNDLEDALEIIKIVTANG..ITISPRIQIFDENSDsk...idVPEGKTAIATVCSITIDGILLNQGVPVEPAYGGTLNIKN..NEPVNFQDLISYSGTSIDPIKIFMSR.....KTTSVLDVLDTGTGKILANMRTIPASASEKALDVINRINASEIGGVI..RTGE..SGEYV.FGAPVD.FGMSG.VPVY.VGT..NVICAVEEAGIDVATYPVSTVLEYSNMSK-l.........
O28056_ARCFU/83-322              ...........l-GEFSERIEYNVYLSNFDLYTLSGLVPTNFAFID..............KSLFERAMEIVEECISQP..ISISNRIFIAEEGESlg..gytVPKNSFALGVISNTIYDVILKTAGVNTTPEYAGLMSVEN..MEARGLTELISYFGTTLSPGLLLLKA.....GLTSVYSACKTGRGEIIVAIRSFSRYAMDIARRELEIAESKGLRGVI..KILH..PSDRI.FGLPAA.-NRAR.LVVS.AGL..NMIAPLFENGIIPEVRVNEFFVDFRDFRV-i.........
Q6LZL7_METMP/81-300              ............IGSVFSQVIEKLYLSDFP-----SKVLINTAKF-..............EGDYKTIKEMVLRSFEAG..YSVGDYLNIKKK---.......--GNTVSVETLCSITFDNFLLKNGIIPTPEYGGIVKFED..YEPVNFEGVIDFKSSSIDPLVAFIMQ.....GKTDVIGVIENGEGLVPANFRVIPKSSEKQFETILKKD---MLNSVL..AYGT..--ENV.LGMNLN.PEQIG.VVLV.GGL..TPLCVPHESGYTADISAATQLKDISSMEK-k.........
Q3ZXS5_DEHSC/100-340             ............VGFVIDKIERLAYMTDFDLDNLSGMVPVNISFFA..............KDQFKPALRAMAQAYKAN..LCVSDLVCIAHEGDKis..ditVPEGQVAFATVCSIVINGTLLKAGIPMDSRFGGTLQFHQ..HKPWRFTDMIYYTGSSLDPSEIFIAS.....RMTSVSEVARRGEGKVLCNFREIPAVSLPLAEKIIAKLKNAGINGVL..VIGE..AGKSI.CEMPVG.LNKVG.MIMM.GGL..NPVASAVESNIPAASHAMSGLVPYSSFTS-y.........
D3E025_METRM/83-314              ............VDFTLSKFKERIYLTDFDYKKKEGNVIVNTSNIL..............E---NKAFDIIKEVFAAG..VCVSPLINAKKT-EI.......NGKKGYVMKTICGTTIDGVFLKNGIPSIPQYGGLVDIED..YYPTKFSELISYRKTSITPLDAFIAK.....GMTSVLEVAEHGTGTIPANFRIIPESGLEKAKEIFEKLEKAGIGGIL..EIGE..ISENI.LGIPVP.EGMVG.ISII.GGI..TPFCAAQEMNYKVDIKTGEEFINYNKLKE-l.........
D3S704_METSF/319-536             ............IKTALSKMFNAMAKVTYDIDEADGNVVVNTAFIE..............KKYTDEALDLLKEAYKKG..LGISDRFGIVEE---.......--EDKIKIQTVCAVTLDGIFLRNSVPVIPRYGGILEITE..DK-ERFIDIIGYNGSSLDPHEVFFNF.....V---------DCEKTFLAGFREVHRVAREKLEEVLKKL---NWNGIK..AIGE..PNNEL.YGIGVN.KDMCG.VVTI.GGI..NPLVLLKENEIPIELKAMHEVVRFSDLNS-y.........
Q0W3T7_UNCMA/85-325              ............IGFISTRIKEIELMTTYDPATNTGEVAVNICYIP..............KDRFEDALGAIKRVVNAG..YAISPRIKIVDEGEEil..endVPLGSVAFASVCSITLDGVLLKNGIPVNLKYGGILWIQN..GEVQRFTDVIDYSGTSINPMSVFTSR.....KMTSVNKAIETGTGGVLANVREIPVAAREKAQELIYQMKAAEFLGVV..SGCE..PVRPL.LGVPIE.LGKCG.IVEY.SGI..NPFAAFVELGIKTRIMPLATVINIRELKKM..........
F0T764_METSL/84-315              ............VDFIFSKFEDMIHQTTLNPSDGTGKVIVNTSSF-..............-KYEKDIIDLLKSVFERG..VAVSNYVKFHNT--P.......VEGEELKFDTVCGTTIDGMLLGKGIPVIPKYGGIVKVND..YVPTRFTELISYKKTSMTPLEAFTDK.....NMTSVLKVIENGNGTIPANFRLIPKSARASAASLFKDLEKIGIHGLL..KMGK..EGESV.LGIPVD.DNMVG.IAVT.GGI..SPLCAAKEAGYDVNIKLAENNVEFKGMEN-f.........
D2BI12_DEHSV/100-340             ............VGFVIDKIERLAYMTDFDLDTLSGMVPVNISFFA..............KDQFKPALRSMAQAYKAN..LCVSDLVCIVHEGDKis..ditVPAGQVAFATVCSIVINGTLLKAGIPMDSRFGGTLQFHQ..HKPWRFTDMIYYTGSSLDPSEIFIAS.....RMTSVSEVARRGEGKVLCNFREIPAVSLPLAEKIIAKLKNAGINGVL..MMGE..AGKSV.CEMPVG.LNKVG.MIMM.GGL..NPVAAAVESNIPAASHAMSGLVPYSSFTS-y.........
C7P654_METFA/83-303              ............LGSIYSNILEKTISANYNF----GYVVINRCHV-..............YADFNDVLKIIKSVYESG..LAVGDRIGIMDR---.......--EKFVEVNTLCSLNFDNILLQNGIFPLHLCAGVVKYED..GKPVEFKEIIKYKCTSIDPLRAFIEK.....KETDVMGIIENGEGYLPANFRCFGVGFLEKFKSILEKD---ELKCVI..SYGT..--ENV.LGLDVG.DDKVG.VALI.GGL..TPIAPFVENDYYVEMSPMSSTVRLESLYK-i.........
D3S704_METSF/83-303              ............LGSIYSNILEKTISANYRF----GYVVINRCQV-..............YADFNDVLKIIKSVYESG..LAVGDRVGIIDR---.......--EKFVEINTLCSLNFDNILLQNGIFPLHICAGVVKYED..GKPVEFKEIINYKSTSIDPLRAFIEK.....KETDVIGIIENGEGYLPANFRYFGIEFLERFESILEKD---ELKCII..SYGT..--ENV.LGLDVG.DDKVG.VALI.GGL..TPIAPFVENNYCVEICPMSSIVRLESLHK-v.........
Q12VH9_METBU/85-324              ............LGFVITRIEELIYNTNYDPISKEGNVIVNLSTLD..............KNDFDNALDVMKYAASGG..MCISPNIKIFEEDSDsg...vyVPEGSVGIATVCSITYDGVLLRNGIPVKPVYGGILEMEH..NDPVQFRDLISYSGTSIDPVKIFMIR.....HATSVLDVLDTGNGRILANIRTIPSSAVDKAQEVLHQLEASGLGNVM..NIGS..SAYDL.CGAPVE.EGLSG.ILVG.VGV..NMISAVEEAGIPVSTSPVSTVLDYKVMSK-l.........
C7P654_METFA/319-536             ............IKTALSKMFNAMAKVTYDIDEEDGDVVVNTAFID..............KNYIDEALDLLKEAYKKG..LGISDRFGIVEE---.......--KDKVKIQTVCAVTLDGIFLRNSIPVIPKYGGVLEITE..EK-ERFIDIIGYDGSSLDPHEVFFNS.....V---------DCEKTFLAGFREVHRVARERLEEILERL---GWNGIK..TIGE..PNNEL.YGINVN.KDMCG.VVTL.GGT..NPLVLLKENEIPIELRAMHEVVKFSDLKSY..........
F6D855_METSW/84-315              ............VDFIFSKFEDMIYQTTLDPSKGKGAVVVNNSTF-..............-TYSKKVMDIIEKVFKMG..IAVSPYTNTYPIKDG.......--NNKIKVETVCGTTIDGMLLNQGIPVIPQYGGVVKVED..HVPVRFTELIAYKKTSMTPLEAFTDR.....EMTSVLQVIDEGNGLIPANFRIIPASAKTQAMEIFKDLEKIGIFGLL..KIGD..DGESV.LGIPVD.DNMVG.IAVI.GGI..SPLCAANEAGFDVDIKLAENTAEFSEMKSI..........
Y159_METJA/86-306                ............LGSIYSNILEKTISANYRF----GYVVINRCQV-..............YADFNDVLKIIKSVYESG..LAVGDRVGIIDR---.......--EKFVEINTLCSLNFDNILLQNGIFPLHVCAGVVKYED..GKPVEFKEIIDYKSTSIDPLRAFIEK.....KETDVMGIIENGEGYLPANFRYFGVEFLERFETILEID---ELKCII..SYGT..--ENV.LGLDVG.DDKVG.VALI.GGL..TPIAPFVENNYCVEICPMSSIVRLESLHK-l.........
B9AG53_METSM/331-559             ...........p--FLLSKSWNLIQKVNFDVETRKGDIIVNVSYIN..............KDSLDKAIDIMKETYESN.pKYINPYYQLVEHPT-.......-DYSKIGIATICSLSIDGLLINNGIMSNPKYGGLLELNE..-SP-LFIDLISYNGSSVDPHKIFIAK.....NMTSITRNI--GSNKILASLKEIPYISRDYAVHLLNILKNIGFS-IY..KIGK..PRELT.YNAKVD.NYNFG.VVAG.SGL..NLIAALKEKGIDVEVKAIAKLMKFEKMER-l.........
D5EGZ4_AMICL/87-327              gtpsfeteklss-------------FYSFNGEKKKGFIVANCLLLE..............KNKLSIALQELKKAAFTN..VWVSSLLGISKEPEKlw..kcdLPDKYVGLVCVSSRNYDVALQKKGIYVETSATGLYSLKN..FTPRGFTEIISHTGTTLSPGEILIRG.....RYTSVCRLAETGEGLVTAAIKTFPSFLYKELQEALAHLDPSIFSGLI..FHGG..LIPPS.YRISSK.DRNKGyMVIY.GGA..NLFSPLIEKGIATNLSIASSLYDVEQMTDI..........
Q3Z7W5_DEHE1/100-340             ............VGFVIDKIERLAYLTDFNLDTLSGMVPVNISFFA..............KEQFKPALRAMAQAYKAN..LCVSELVCIAHEGDKia..disVPAGQVAFATVCSIVINGTLLKAGIPMDSRFGGTLQFHQ..NKPRRFTDMIYYTGSSLDPSEIFIAS.....RMTSVSEVARRGEGKVLCNFREIPAASLPLAEKIIAKLRNAGINGVL..VVGE..AGKSV.CEMPSG.LNKVG.MIMM.GGL..NPVAAAVENDIPAASQAMSGLIPYSSFKNY..........
F8AN19_METOI/322-537             ............IMPVLSKMLSMLHKVNYDMESERGNVLVNTAYIN..............RKYEEEVLDALKECHKSK..TVISDRIGMEIK---.......--GDKIIINTLCSSTIDGIFVKYGVPIIPYYGGVLELGK..---NRFIDIISYEGTSLDPHEVFFNR.....V---------DGKKTILSGVRKVPMAARDSLINIAEKL---NWPGIL..EIGK..PNNDI.CGIKVE.KGMFG.FVSL.GGI..NPFVIIKNKGIPIEIEALHGIKEYSELV--pl........
D9PU67_METTM/328-557             ............VRFLLSKAWNLINRVDFNHRDFSGRIIANISLVK..............REDLDEALEIIRDVLGKRpeFSTLPLIGITDE---.......--GEMAGIATVCSLTLDGILIKNGIMSTPKYGGLLEVGV..RDP-RFVELTAYSGSSLDPHEIYVSK.....NMTAVLEAL-DGPGRVLASLREVPYLARDHTTDLIEDLSEAGFS-IL..KIGK..PSEIV.YNARVE.KYHAG.IVTP.GGL..NPLAAVREAGIDIRIKAVEGLMELKEFM--yv........
Q58GH9_METVO/372-598             ............VKPVLSKMISMMHEVKFDIKNESGQIIVNMAKIDlnql.....nklenEKNEEDVLKLLKEVYKKD..LSISNKLKIEED---.......VKNGFLNIYTICSLTFDGILLNNQIPVLPYYGGLLERPE..---MRFIEAISYEGTSLDPHEVFFDK.....S---------DGKTTLLAGIRKVPMFSKSKIEEIYDDL---GWNSIL..EYGK..PNNDL.CGIRVE.SEMLG.YVTL.GGT..NPFAYLNVNKIPVKIETHYRIMDYSELDDY..........
G6FK99_9EURY/5-245               ............LKFVHTRIEEYAMQVTYDPREGGGLVVYNLSFVP..............NGDLDAAITVMRDTFRAG..LCVSGLVRFVGEGEAag..etkVPAGHTGIITICSSTLDGILLRRGIPSNPIGGGVVEIEG..RIPRRFIHLILYEHTTIDPLQALLSQ.....EITSVTGMMRRGSGNILANIRQCHMEAEGQIGEVIDDLAGSSFSPIL..DVGL..PNTPA.LGVTVD.PQYMG.IVAL.GGT..NPMAAIKERGIAVTTHAIKGLMDVRDLEEI..........
D8K457_DEHLB/90-330              ............VGFVSDKIELLAYQSTFDVNRQEGLIPVNISLFP..............GNQFGDAMKVMAPIFRAG..ICVSDLIAVEQAGGNlg..gmpVPEGYIGLATVCSITINATLLKSGVPMDSRFGGTLQYRQ..NRPWRFTDLIHYTGSSLDPSEIFIAS.....RMTGVTETARRGSGKILANFREVPAMSLPMVRDLMFGLEKAGIRGLV..DIGE..SGKPV.CEVPVG.LNKVG.LILC.GGL..NPVAAAAEAGIATRNRAMSGLMDFHRLRR-f.........
E1QIV0_DESB2/84-324              ............VGFVAARADALTYGMNFRLRQGKGSVVVNISTFE..............TARAGHAIEVMRRVYQAG..LSMGQRLALAGAGARlg..rlvVQPGEMAVATICSISVNGVLLAEGIPTTNRFGGLLQMRG..GKPQRFLQIINYDGTTLDPLEIFIKG.....QMTSVSQAAATGDGVVGASFREIPTQAAEAARRLGARMERAGLGGIL..MIGR..PGQPL.LEVPVS.QGRVG.MIVL.GGL..NPMAAVEEVGVPTGNRAMGTLLPFEDLR--pf........
D2ZNH3_METSM/83-312              ............VDFIYSKFEEMIYLTSFNYMNRTGNVVVNTSTI-..............--YDEEAFNIIKDVFKSG..LCVSPYINLKEGN--.......-SKEEIQIKTICGTTIDGILLNEGIPTIPLYGGLVKIRD..YVPTKFTELISYKKTSVTPLDAFVAP.....GMTSVLDVINTGNGTIPANFRLIPSVGRERALNIINKLEKIGIGGVM..AVSE..EGKNM.LGVPVP.EGMVG.IAVS.GGV..TPFCAAQELGYDIDIKIAEEIEGFETLS--pi........
F8AN19_METOI/84-306              ............IGSVFSQIMEKVYLSNFP-----TKVIINKTVF-..............EGDYDIIRDLVLKVVDSG..FSIGDYVNIRKDSEN.......--PNLVDIETLCSITFDNFLLKNGILSMPKYGGIVKFED..YEPVYFEGVIDFRKSSIDPLEAFITR.....GKTDVLGIIENGEGYLPANFRIIPSSVMEKFENLLKRD---LLNGVL..SYGE..--DNV.LGLSLN.EGEIG.VALV.GGL..SPICPAVEKGYPVKINAATTLMDLSLMEK-r.........
A6UTI8_META3/327-542             ............ISSVLSKMNSMMHNVNYDIEMERGAVLVNTGYID..............KSYKQDVIEILKECTNKK..QIISDKIGIIDK---.......--DNKIQINTLCSTTIDGIFLKYGIPVIPYYGGILELNK..---NRFIDTISYDGTSLDPHEVFFNK.....V---------DGKNTILSGIRKAPMSARENLINIMEKL---NWTGII..EIGK..PNNPI.YGIKVE.KGMFG.FATI.GGI..NPFVVIKNSGIPIEINALHDVMEYSDLTF-i.........
D1YUP9_METPS/8-248               ...........m-MFTNARIEEIMYNVTFNPKTRDGDIVVNLSVVD..............KNNLDEVLELFRQVMYSG..LSVCSYVKLFDEGETfs..gyrVAPGKAGIATACSITIDGVFLKQGIPVRPKFGGIVQVKD..RQPIRFTDMIRYDSTTIDPLEVLMSQ.....ELTSVKEMTRTGSGKVLANFREVPMTAKDDVDHTINRLLTAGFYGIL..EVGE..PNTPV.LGVDVD.RDHMG.VIIT.GGT..NPMAAVQESGIPIVTKAIKGTLDFREMKK-l.........
F7XQB9_METZD/8-248               ............LQFTSSKIEDLMYRTTFDPKSGDGDLIVNLSLFR..............EEDLEDVLNIFKTTISSG..LAVSPYVKMLHCGDTia..gyrIEEGMAGIATVCSITIDGILLKSGVLVKPHFGGLVQIRD..GMPVRFTDVLRYASTTIDPLEVLMSQ.....EVTSVTRMLRTGSGKILANLRGAPMIAREKVESVLADMMDAGISGIL..EVGE..PNTRI.LDVSVE.RDHFG.IVVI.GGT..NPMAVVQESGIYIRTNAMSTLIGIDEMRP-i.........
G7WN74_METH6/89-329              ............VGFVNARIEEYMYRSSFDPGSENNRVVVNTSLLD..............KRDSERALAAMKAVFDAG..FAVSRRVLIQDEGEEmg..gaaVPRGFLGISTVCSITVDGMLLRGGIPVNTTFAGVVDVRE..GSLYQFTDLLAYAGSSLDPIRVLMSR.....KAARITGAVKTGNGGLLANLREIPVAAIGQARELLEMAKGAGIDGVM..RISE..PGEPN.MGCPVG.AGKVG.IALC.AGV..NAVLAAEELGAEIRTTPISSIQEYGRMKE-l.........
A9A6B8_METM6/316-533             ............VTPVLSKMLSKMQTVNYDIEDKKGTVVVNSARIP..............IEYKEEAINALKDSYENK..LAISDRLKVEYD---.......--GEFLNAYTICSLTADGVFLKNKIPVIPYYGGILEVKA..DK-KRFIEAIDYEGTSLDPHEVFFNK.....A---------DGKNYILAGIRKVPMSAAAKLIEINEKL---GWNSII..EIGR..PNNDI.CGVRVE.KCMFG.ITTI.GGT..NPFAYIRKNNIPIEMKTLHKSIDYSELTHY..........
Q8TYG2_METKA/85-324              ............VGMYISLIEEMAYRCSFDPEVMKGKVVCNISVVK..............REHLDDFLDAVVETYRAG..ISPSPLVAVKEDLSDhd...veVGEDEVAVLTVCSVTIDGVLINRGIPVTPVCGGLLYLED..GEPLGMQEYIKYEGSTVDPLHVFVAK.....GMTQVERVLETGTGLVPANVRYVPWAALEDVEHVERELEKADIRGIV..DVPK..VEGEI.LGIPLP.PRSLG.IVAY.GGL..VPVALLEERGISTRTYPTRTLVEYSSLED-a.........
A7I5N3_METB6/83-315              ............IGFVISKLERLAFRSTFDPATGTGDVAYNLSFVQ..............KDDLDRALVAFDEVNRAG..CGFFNSYRILDDDPR.......VPSDCVGVITLCSITMDGLFQRNGIPVKMAYGGRLEIEN..NVPQRFRDLIGYRGTTIDPLELFISS.....GLTSIHDFTRTKTGIALANVREVPRSAQGEIKQIIRLMNDCGFIYPV..TMGN..---HI.FNLPDS.SYRLS.IVAY.SGL..NYIGNCVEQGIAIRTEIGAGNIPFSKVAD-i.........
D3L1C4_9BACT/91-331              ......iglssm------ETEMLIMKSDLDPCSNKGKVIVNITSVP..............EELKDEALSLLAEVSESN..VIVSPLVAVLPQGKRiw..nyrVPEGRCAILCLSSANYDVALRRCGVYVETVATGLFRLQG..YKGKGFVDVISHSGTTLSPGELLIRG.....GFTDVMSAVRTGKGCVTAAIKTFPSFMYEKVVEAIKDCKNDNISGLF..ELGY..LMPPK.YQMSIK.DRTRG.YMLIfGGA..NYLAPLVECGITDALSIASGLYDIEDMR--l.........
Q2FSW2_METHJ/5-245               ............LRFVSHQIEDFAMQVTFNPVEGTGTVVYNLSLVR..............VEDLEQTISVFRATCEAG..VSPSSLIRILYAGEEld..gfvIPQNFCGILTLCSTTLDGLLLQRGIPSNPIGGGVIEVAE..NIPKRFTHLIKYEYTTIDPLQVLVSQ.....EITSVHQVMKHGNGSILGNIRECHMEAEDDVEEVLDELTEGYFTGIL..DLGL..PNTPC.LGVAVD.PQYMG.LAAL.GGT..NWMAALREEGISVTMQAMKGLCDISTME--fv........
D3RXS6_FERPA/85-323              ............IGSFIELREEYAYNANFDPFKRKGLVSLNIGIIR..............KRDLEKSLELIKACMDAK..LAVSRFVKIYEREAGn....tkIPKGKVGIGLVSTSVVDAALIGSRISSFPTFAGILQYSD..WKPLRFVHAISYYGSTLDPIDLFIRS.....GFCSVKDAVERGNGNVPADVREIPLVLRKRAVEIIEQLEKIGINGAV..YVSG..AENDA.LGIPVN.NYKAG.VVVI.AGS..TPLVYLKEKGIDVEIKILAAFERIENLEEI..........
H1YYZ9_9EURY/85-316              ............VGFVISKLEKLAFRSNFDPETCTGNVAYNLSFVP..............EEEEEGVAKAFDDVIGAD..YGFFTSYKIIDSDPR.......IPKGHVGFITVCSVTMDGILQKNGIPVHMAFGGTMKIRD..KIPVGFTELIGYRGTTVDPLILFINS.....GMTSISETTKSGNGIMLANIREIPESSEDSVMSIASSMQKAGFRFPV..TTGC..---GV.MNIRPD.SYRTS.IVAY.TGM..NLIGCGIERGYNIKTEIGAGNIPYSKFE--l.........
Q46DJ8_METBF/85-323              ...........f-GFVISRIEEMAFRTTYNPKTNEGVVPVNISYFD..............KDDLETVIEVVSYTAHEG..YMISPRVRIIEEDEEl....lsLPPGKVGIATVCSVVFDGLLLKAGIPVEPAYGGIIQIEN..RKPARFSDLISYSGTSIDPIQIFMSR.....KTTSVLDVLEKGEGKILANMRQINCSAYERAREVLKTVEKVGLAGYY..PLGE..VDETL.FGAPVE.TGKFG.IAIV.GGI..NGICALEETGIKMKTNPVSTVMEYNTMTEI..........
Q46BP9_METBF/8-248               ............VQFTSSRIKDLMYRTTFDPKKMDGDIILNLSLID..............KKDLDDVLGIFKMVISSG..LSVTPYVKIVSEGESig..dltVEKGKVGVGTVCSITIDGVLLKAGIPVNPKLGGVVQIRN..GVPVRFTDVLTYVSTTVDPLEILMSQ.....GITSVSEMLRTGSGKVLANLREAPMVARDEIESCLSDLLDAGFSGIL..EVGE..PNTRV.LDVPIE.RDHLG.IVVI.GGT..NPMAVVQEYGIAIDTSAMSRLISFKEMSR-i.........
G6FHR9_9EURY/83-314              ............VGFIISKLERLAYRCSFNPETSTGDVAYNLSIVP..............EERLADATAAFDEIVAKR..WGFFSGYRVIDKDPR.......IPHGSAGILSICSITMDGVFRREGIPVRMAYGGRLAMQH..DEATHFVDLIGYRGTTIDPLQLFISS.....GLTSLSSLVSTGSGTALANVREIPALAENRAREIVARMKKAGFSFPV..AMGS..---SV.FNLVLD.PYRLA.LVAY.SGM..NLVAHAYEKKIPIRTEIGAGTIPFSRI---iq........
G7WQV7_METH6/7-237               ..........lv--FSLSRIENLMHQVSFDPRRMEGEIITNTSLVD..............LKMLDPTLRIFRDVIESG..LAVSPYLKVETL---.......--GTKAKIMSACSITISGVLLKAGVPIRPRGGGVIEVID..REPVRFTDMLMYWATTIDPIDVLISQ.....ELTSVVEMMETGSGRILGNLQEAPMIAAERIEERLDLLAEAGFSGVL..DLGD..PNMNV.LGVSVE.RDHVG.LSLV.GGT..NIVAAAMSHGIRIETESISSLTKIQEMTHI..........
B8GJM0_METPE/83-314              ............IGFIISKLERLAFRSTFNPITGTGDVAYNLSTIP..............EERVDEVTAAFDQVIDAG..CGFFNAYRIIDRHPK.......VPAGHVGFITLCSITMDGVFQQHGIPVKVAYGGTLAVEN..RKAIEFTNLIGYRGTTIDPLQLFISS.....GLTAIKPLVTTRSGIALANIRQVPLPAESQVSDLINAMRNNGFVLPV..EMGQ..---TV.FNVPPD.PHRIS.IVSY.SGM..NLIGNCVELGIPIKTEIGAGNIQFSKV---vg........
Q8THV7_METAC/119-358             ...........f-GFVISRIEEMAFRTTYDPETDKGDVVVNISYFD..............KDDFETVVDLVSYTAHAG..YMISPRVRIFEEDSEse...ihLPPGKIGIATVCSVTFDGLLLKAGIPVEPAYGGILQIEN..KKPSRFLDLISYSGTSIDPIKIFMNR.....TPTSVLEVLEKGDGKILANMRQINASAYDTAKGIMKKAEKVDLAGCI..TIGE..IDEFL.LGAPVE.TGKFG.VAVV.GGI..NGICALEETGIEIETNPISMMLDYRTMSEI..........
F6D855_METSW/333-564             ............VKFLLSKAWNLIYNVDFNLETQKGKVIANVSYVK..............NEDLEDALQIFDRVMASKpnYCTNKFFKIIPD---.......VEPGKTGIATICSLTIDGILTKNGIPAIPQYGGILETEG..KEP-RFIELTAYSGSSLDPHEVYISK.....NMTSVLDSL-NGKGRILASLREIPYIARPRAIEVLEDVKEAGFS-IL..KVGK..PSELV.YNAKVE.LYRAG.IVAP.GGL..NPIAAIREAGIHVEPKAVETLMNISDMEE-f.........
D7DT16_METV3/364-581             ............VKPVLSKMISMMHEVKFDLNNESGRIIVNMAKID..............LKYEEKVLKLLKEIYKRD..LSTSNKLKVEID---.......VKNECLNIYTVCSLTFDGILLENQIPVIPYYGGLLERPE..---MRFIEAIAYEGTSLDPHEVFFDK.....A---------DGKTTILAGLRKVPMYSKSKIEEIYETL---GWNSIL..EFGR..PNNDL.CGIRVE.TEMLG.YVSV.GGT..NPFAYLNINDIPVKIETHYKIMDYSELEDY..........
D1YVU6_METPS/85-325              ............LGFVSTRIEEYEFKTTFDPATDTGEAVVNICYIN..............KSDLDRSIDTLKRVVEAG..YAISPRLKVVDEGQEil..endVPEGQVALATFCSITIDGVLLKRGIPVNLKYGGLIRVKD..HNAERFTEVIDYHGTSINPMNVFVSR.....KMTSVLKVLETGSGYVLANIREIPVNARENARQIISQLESADIHGIF..SGCE..NMRPL.LGVPIE.TGKCG.IASY.SGI..NPFAALTEMGIKTRIIPLSAVMNVNELKR-l.........
H8IAG6_METCZ/85-325              ............LGFISTRIEDYEFRTTFDPSANTGDAVVNICYIN..............KADCDKALEVLKQVVEAG..YAISPRLKVVDEGQEil..endVPEGQVAIATFCSITIDGVLLKRGIPVSLKYGGIIRVRD..NKAERFTDIIDYRGTSINPMNVFVSR.....KMTSVLKVLETGSGNALANVREIPINAREKALGIIEELRGAEVYGIF..SACE..SVRPL.LGVPVE.PGTCG.IASY.SGI..NPFAALAEMGIKTRIIPLAAVMNSKELKR-l.........
Q8PXY1_METMA/85-323              ...........f-GFVISRIEEMAFRTTYNPETDKGDVVVNISYFD..............KDDFETVIELISYTAHAG..YMISPRVRIFEEDSLe....msLPPGKIGIATVCSVTFDGLLLKAGIPVEPAYGGILQIEN..KKPARFLDLISYSGTSIDPIKIFMNR.....TPTSVLEVLEKGEGKILANMRQINSSAYEMTGKILKKAEKVGLAGCI..TLGE..IDEYL.LGAPVE.TGKFG.AAVV.GGI..NGICALEETGIEIETNPISTMLDYQTMKEI..........
G0H4D6_METMI/81-300              ............IGSVFSQVIEKLYLSDFP-----SKVLINTAKF-..............EGDYKTIKEMVLRSFEAG..YSVGDYLNIKKK---.......--GNTVSVETLCSITFDNFLLKNGIIPTPEYGGIVKFED..YEPVNFEGVIDFKSSSIDPLVAFIMQ.....GKTDVIGVIENGEGLVPANFRVIPKSSEKQFENILKKD---MLNSVL..AYGT..--ENV.LGMNLN.PEQIG.VVLV.GGL..TPLCVPHESGYTADISAATQLKDISSMEK-k.........
E3GY38_METFV/326-554             ..........iv--PLLTKVWNLIGQVDLDIKKLDGKVIANLSTID..............KKYLNDALEIFQTIIDEKpeYSVFPSIKLKER---.......--DNKVDIATVCSLTIDGVLINNGIMSVPRYGGLLEIKN..NK-KRFVELIDYSGSSFDPHEIYISK.....NMTKIYRS--SKTSTILASLREIPYLARNKALKVIKKLKKANFQ-IM..KVGK..TNEIL.YNAKVE.RYRVG.IVTP.GGL..NLIAALKENGIKVNIKSAELLMDINEFS--ll........
F6BCA0_METIK/84-304              ............LGSIFSQIMEKLYLADYR----NGIAVVNKSIV-..............YGDHNEIKDTILKVLEFG..LGVGDKVNIVEE---.......--KNYTRIETLCSVTFDNWLLSHGILPIPKYGGIVKFED..YEPVQFEGVINYKSTSVDPLEAFIMQ.....RKTDVWGVIENGEGYVPANFRVIPKEAKEKFEKLLKKD---TLNCIL..SYGE..--DNV.LGLNVE.EDEIG.IALV.GGL..SPVAALVEKGYYVELNAASTIKKVSFMEK-v.........
Q8J2Z0_METMI/316-533             ............VTPVLSKMLSKMQTINYDIEDKKGNVVVNTAKIP..............IEYKEEAINALKDSYENK..LAISDRLKVECD---.......--DKFLNAYTICSLTVDGVFLKNKIPVIPYYGGILEVKA..DK-KRFIEAIDYEGTSLDPHEVFFNK.....A---------DGKNYILAGIRKVPMSASEKLIELNEKL---GWNSII..EIGR..PNNDI.CGVRVE.KCMFG.ITTI.GGT..NPFANIRKNNIPVEMKTLHKSIDYSELTHY..........
Q0W777_UNCMA/8-248               ...........m-MFTDARIDSIMYQVTFNPKTREGDIIANLSLVD..............KKDLDETLEIFRQVMYSG..LSVCSYVKLFDEGDIfs..gltIPAGKAGITTVCSITIDGVLLKSGIPAKPIFGGIVQVKD..RVPVRFTDSIRYECTTIDPLEVLMSQ.....DLTSVREMMRTGSGKILANLREVPMAAKDDVDRTINRLLTAGFYGIL..EVGE..PNSPV.LGADVS.RDHMG.IIIT.GGT..NPMCAAQEAGIPIITKAIKGVLDFHEMKK-l.........
Q2NHI2_METST/78-305              ............VDFTFSRFQEKMYNVSLDYKKATGSVIVNISSIN..............--DL-DSSKIITDVFKEG..LSVSKHYNIVEK---.......--DDKTYIETVCGTTIDGVFQQQGIITKPLYGGLLKVED..YVPINFTEQIAYENTSITPLEAFTGH.....DNTSVIDVINNGTGVIPANFRIIPEVKKQHALAILDNLKTIGIGGVI..HIGN..PGEAV.LGIPVP.EGMVG.IAVV.GGV..TPLCAAREEGYDLSIKLADGYAEYSNMI--ns........
E1RE52_METP4/108-338             ............IGFIISRLEKLAFKSDFNPETGRGNVGYNLSVVP..............EDQVNGVSGAFDEVIESG..YSFFSRYKIIDTDPR.......IPSGYAGFLTVCSITMDGVLQKMGVPVRMAYGGVIDIKN..GKPLGFSNLIGYRGTTIDPLSLFITS.....GNTSIGQTCAEKAGSVLANVRQVPQDAADLVSEGSRLMRECGFLFPV..DMGS..---GV.LNTPVD.PCRIS.LIAY.SGM..NLIGNAVEKGFELRNEIGAGNMPFSF----fe........
A0B970_METTP/33-263              ..........lv--FALGRIENLVHQVSLDAKKGTGRVITNRSLVA..............RDDLHEALEIFKDAIDSG..LAVSPLVRLEDVGE-.......----RFMIHTVCSMTIDGYLIKHGIPVRPKGGGLIEVID..RETVRFTDIIMYWATTIDPLDLLIAQ.....ELTGICEMMRTGTGRILGNLHEAPMIAHDTIEDLLDELRDAGIMGVI..ELGD..PNMDV.LGMPVE.RDHLG.VALI.GGT..NPAAAAVEFGLDIETASISGLTEISEMCHI..........
C9RDX5_METVM/319-536             ............IKTALSKMFNAMAKVSYDIDESDGNVIVNTAYIE..............KQYYDEAVELLKEAYKQY..LGISDRFGIVEE---.......--QDKIKIQTICAVTLDGIFLRNSIPVIPRYGGILEITE..DK-ERFIDIIGYEGSSLDPHEVFFNF.....V---------DCEKTFLAGFREIHRVAREDLENVLKKL---NWRGVK..AIGE..PNNEL.YGINVN.KDMCG.LVTM.GGI..NPLVLLKENEIPVNLRAMHEVVKFSDLIS-y.........
Q58GH8_METTL/84-304              ............MGSIFSQIMENLYLSNFP-----VKIIVNTATF-..............EGDYKTIKNLILKSFENG..FSVGDYLNIQNK---.......--GGLVEVETLCSITFDNFLLKNGIIPLPRYGGIVKFED..YEPVHFEGVIDYRDSSIDPLVAFITQ.....DKTDVLGIIENGEGYLPANFRVIPSSTKEKFENLLKKD---LLNCVL..AYGE..--ENV.LGLNIN.EEEIG.VALV.GGL..TPLCIPIEKGYKMEINAAATK---------lknlvsmerr
Y159_METJA/322-539               ............IKTALSKMFNAMAKVTYDIDEADGDVIVNTAFID..............KKYLDEAFDILKEAYKKG..LGISDRFGIVEE---.......--NDRIKIQTICAVTLDGIFLRNSVPLIPKYGGILEITE..DK-ERFIDIIGYDGSSLDPHEVFFNF.....V---------DCEKTFLAGFREVHRVAREKLEEVLKKL---NWNGIK..AIGE..PNNEL.YGIGVN.KDMCG.VVTM.GGI..NPLVLLKENEIPIELKAMHEVVRFSDLKSY..........
#=GR Y159_METJA/322-539    SS    ............---HHHHHHHHHCC---BTTTTB-EEEEEEEEEE..............GGGHHHHHHHHHHHHHTT..-SSSSEEEEEE----.......--SSEEEEEEE-CHHHHHHHHCTT--EEEEEEEEEEE-S..S--EEEEEEEESTT-SS-HHHHCGGG.....-----------SSSEEEEEEEEEETTTHHHHHHHHHHH---T-TTEE..EE--..TT--B.TTB---.TTEEE.EEEE.-TT..HHHHHHHHTT---EEEEEEEEEEGGGSEE-..........
F0T764_METSL/333-564             ............VKFLLSKTWNLIYQVDFDVETHAGNVITNVSYIR..............KQDLDDAMDIFEEVMKVGpkFCTSKYFATVPGNE-.......--KDKVGIATVCSLTIDGILTKHGVSTTPQYGGILETNS..KQP-RFIELTAYNGSSLDPHEIYIAK.....NMTSVNEAI-KGGGRVLASLREIPYVSRQDAVEVLEEVQDAGFS-IL..KIGK..PSELV.YNAKVE.RYHVG.IVAP.GGL..NPIAALKEHGMDVEPKAVETMMKVSDMEE-f.........
A6USA1_METVS/81-300              ............IGSTFSHVLDMIYISDFP-----SKVIINTATY-..............QGEYKKIKELIYKSFEAG..YCVGDYLTIKKK---.......--GDSTSVETLCSVNFDNFLLKNGIISLPKYGGIVKFED..YEPVNFEGIIDFRSSSIDPLVAFITQ.....KKTNVLGVIENGEGFVPANFRAIPKSCEEKFERIVKNN---MLNSVL..AYDT..--ENV.LGMGLN.QDEIG.VVLV.GGL..TPLCIPYELGYPMHIAEATTIKDMSTLD--tr........
A6USA1_METVS/316-533             ............VTPVLSKMLSLMQVVNYDMESHSGNVIVNGAKVP..............IRYREETINALKESYEKK..LAISNVLKIEYD---.......--SEFMNIYTICSLTVNGVFLKNKIPVIPYYGGVLEIKP..DK-NRFIEAIAYEGTSLNPHEVFFNK.....G---------DGKKYILAGISKVPLSANEQFRAITEKL---NWNSVI..EIGR..PNNDI.CGVRVE.KCMFG.ITTI.GGV..NPFSNVNSLGIPIEVKTLHKSMDYSNLTNY..........
Q8J2Z0_METMI/81-300              ............IGSVFSQVIEKLYLSDFP-----SKVLINTAKF-..............EGDYKTIKEMVLRSFEAG..YSVGDYLNIKKK---.......--GNTVSVETLCSITFDNFLLKNGIIPTPEYGGIVKFED..YEPVNFEGVIDFKSSSIDPLVAFIMQ.....GKTDVIGVIENGEGLVPANFRVIPKSSEKQFETILKKD---MLNSVL..AYGT..--ENV.LGMNLN.PEQIG.VVLV.GGL..TPLCVPHESGYTADISAATQLKDISSMEK-k.........
C9RDX5_METVM/83-303              ............LGSIYSNILEKTISANYRF----GYVVINRCHV-..............YADFNEVLKTIKGVYENG..LAVGDRVGIIDR---.......--EKFVEINTLCSLNFDNVLLQNGIFPLQVCAGIVKYED..GKPVEFKEIIDYKSTSIDPLRAFIEK.....KETDVIGIIENGEGFLPANFRYFGVEFLEKFKGVLEKD---ELKCII..SYGT..--ENV.LGLDIG.EDKVG.VALI.GGL..TPIAPFVENDCFVEISPMTSTVRLESLHK-v.........
D7DT16_METV3/81-312              ............IGSISGNIYDKLTKGNYP-----ETVIVNRGTFNlke.......nsesKEELKKLKELILLSFKHG..YSTGNYLKMEQLDKK.......DNNLRLNVETLCNINFDNYLIKNGIMSMPKHGGIVKYED..NKPVNFKGVIEFKKTSVDPLIAFIMQ.....KKTEVLSTIENGEGYIPANFRVIPKSKLDEFKQLLKKD---NLKSVI..CYGE..--NNV.LGINLN.DEEIG.VALI.GGL..TPLCIPVELGYSLDINSTTKIEA-------npniqv....
D2ZNH3_METSM/331-559             ...........p--FLLSKSWNLIQKVNFDVETRKGDIIVNVSYIN..............KDSLDKAIDIMKETYESN.pKYINPYYQLVEHPT-.......-DYSKIGIATICSLSIDGLLINNGIMSNPKYGGLLELNE..-SP-LFIDLISYNGSSVDPHKIFIAK.....NMTSITRNI--GSNKILASLKEIPYISRDYAVHLLNILKNIGFS-IY..KIGK..PRELT.YNAKVD.NYNFG.VVAG.SGL..NLIAALKEKGIDVEVKAIAKLMKFEKMER-l.........
B5YAL2_DICT6/84-326              ............LGFIISKIENLAYQVTLDKSTGKGTVILNLSVIP..............KKDLKKALNIMKDILKKG..YGISEKIIIFDEEEEeispgvfVPEKSVIIGTVCSVTIHGILIKNGIPVSAKFAGVLEVKE..NEPIRFLEAITYNGSTLDPLEIFIKS.....RMTSLSSVVKRGEGKVLATFREIPNSAREDAQNIIEMLKDIGIKGKI..YLGK..PNQEI.FGIPVT.QETSA.LVIV.GGL..NPIAGIIEANIEAENKAMSILYNYEQLQP-i.........
O27611_METTH/88-314              ............VDFIFSKFESMIYNTSFNPDTLEGKVVVNTSRIS..............----PRSIETLKHVMRNG..LCLSPRVKLERDG--.......---DGCIISTICGTTVDGILLASGIPVIPQFGGLVRFED..HQPVNFTELIAYKKTSMTPLEAFTSE.....NMTSVLSVIEEGDGLVPANLRLVPGTGREDAVKILRKLEGIGISGVL..KVGE..PGEDV.LGVPVA.DGMVG.VAII.GGI..TPLCAIQEAGYRAEIKLAENLIEFQSLK--pl........
D5E812_METMS/8-248               ............VQFTSSKIEDLMFRTTLDLKSMQGDIIVNLSIAD..............ADDFVDVLEFLKLTFNSG..LSVSPFLKILESGDVig..dltIPEGKVGIATMCSMTIDGVLLKSGIMTNPKFGGVVQIRN..GLPVRFTDVLTYASTTIDPLEVLMSQ.....DITSVTRMLQTGSGKILANLREVHLAKRDEINSVLSGMMDIGINGIL..EVGD..PNSRV.LDVPVE.RDHLG.VVVI.GGT..NPMAIMKEQGINIRTNAMSTLMDINSMNKI..........
G2MN03_9ARCH/87-270              ..........la--QVRERIATLQSRVSYDPADDAGDLVVAEAVVP..............DEQFGDALADLRALEAAG..M--GPVVTAAEP---.......-IEGGYRLAFPSSVTLDGSLLVRGIRSELQTAGLVEYNPdaGAVTRYVDAISGEGSTMDVVRLLIEA.....DRTGVDAVVEGETGLLIVDNREFPLTRYDETNGIAHAL-RETLGGVL..SISR..PRE--.------.-----.----.---..------------------------------dgp.......
H1YZ00_9EURY/6-246               ............LKFVNHKIEENATKVTYRPAENTGTVIYNLSLIE..............SGDYEFAIDIFREAFRAG..LVVSDRVSFLKEGDEie..sykIPEGKTGICTICSMTLDSLLLRKGIPINPIGGGMVEIEN..MIPRRFTAMLKYEYTTIDPISVMISQ.....GNTKVTEVIKTGNGSITGNIREFHMEAESTVFGVVEELNSSGFTGVL..DVGA..PNTSL.LGVPVT.PDYQG.FAMI.GGT..NPVAAIIESGRSAEVRSMKGLIDISKIN--yl........
Q58GH9_METVO/81-322              ............IGSVSANIYDKIIKNNYP-----ETIIINTGIFDlegslnntndinlgNKTVDKLKDLILSSFMKG..FSTGNYLKMEGLTNEi.....tNNISKLKVETLCNVNFDNYLIKNGIMPMPKHGGVVKYED..GEPVNFKGVIEFKKSSVDPLIAFIMQ.....KKTDVLGVMENGEGYIPANFRVIPKSKLNDFKQLLKKD---DLKSVI..CYGE..--NNI.LGINLN.DEEIG.VALI.GGL..TPLCPPVELGYALEINPSTNIIDNPKI---pvp.......
B9AG53_METSM/83-312              ............VDFIYSKFEEMIYLTSFNYMNRTGNVVVNTSTI-..............--YDEEAFNIIKDVFKSG..LCVSPYINLKEGN--.......-SKEEIQIKTICGTTIDGILLNEGIPTIPLYGGLVKIRD..YVPTKFTELISYKKTSVTPLDAFVAP.....GMTSVLDVINTGNGTIPANFRLIPSVGRERALNIINKLEKIGIGGVM..AVSE..EGKNM.LGVPVP.EGMVG.IAVS.GGV..TPFCAAQELGYDIDIKIAEEIEGFETLS--pi........
A7IAT0_METB6/5-245               ............LKFVNHSIDDYAMQVTYDPAKGTGKVVYNITLVK..............NEDFEYAVSVLRDAYKTG..VSVSGLVRFASSNEKie..dfvVPDGFTAICTVCSLTFDGLLIRRGIPINPIGGGVVEVED..RSPIRFTHIILYEHTTIDPLQVLISQ.....QITSVNDVMRKGSGNILANIREFHMEAEPLVGQVLDELVESSFTGIL..EVGV..PNIPL.LGVPGS.PQYVS.IAAV.GGT..NPIAAIREGGRFVQTQALKGVMDVEKFVE-i.........
A4FYM1_METM5/316-533             ............VTPVLSKMLSKMQGVNYDIEDKKGNVVVNTAKVP..............IEYKEEAINALKDSYENK..LAISDRLKVECD---.......--EEFLNAYTICSLTVDGVFLKNKIPVIPYYGGILEVKA..DE-KRFIEAIDYEGTSLDPHEVFFNK.....A---------DGKNYILAGIRKVPMSASEKLIELNEKL---GWNSII..EVGR..PNNDI.CGVRVE.KCMFG.ITTI.GGT..NPFANMRKNNIPVEMKTLHKSIDYSELTNY..........
B8E0N2_DICTD/84-326              ............LGFIISKIENLAYQVTLDRSTGKGKVILNLSIIP..............KKDLQKSLNIMKDILKKG..YGISEKIIIFDKKEEeiipgviVPEKSVILGTVCSVTIHGVLIKNGIPVNAKFAGVLEVKD..HEPTRFLEAITYNGSTLDPLEIFIKS.....KMTSISSVVKKKEGRVLATFREIPNSAREDAQNIIEELKEIDIKGKI..YLGK..PNQEL.FGVPVT.QGTSA.LVIV.GGL..NPIAGIIEADIEAENKAMSILYNYEDLKP-i.........
B8GHD6_METPE/5-245               ............LKFINHSIEDFAIQVTYNPTEGTGQVVYNLSVFR..............TCDVAPAVEIIRGACRSG..VCVSDLVKFIPEGESld..gykIPPGSTGICTVCSITLDGLLLKRGVPLNPIGGGVIEIVD..RIPRRFTQIIRYEDTTIDPLQVLASQ.....DITSISRVISTGNGTILANIRECHMEAEPLVAELLDDLADSRFTGVL..EVGM..PNSPL.LGVQIS.PQYIG.MVAV.GGT..NPIAAVKEAGYPVITRAMKGLLDVSEMEEI..........
A4FYM1_METM5/81-300              ............IGSVYSQVIEKLYLSDFP-----SKVLINTAKF-..............EGDYKTIKELVLKSFEAG..YSVGDYLNIRKK---.......--GYSVFVETLCSITFDNFLLKNGIIPTPEYGGIVKFED..YEPVNFEGVIEFKSTSIDPLVAFIMQ.....GKTDVIGVIENGEGLVPANFRVIPKSSEKQFENILKKD---MLNSVL..AYGT..--ENV.LGMNLN.PEQIG.VVLV.GGL..TPLCIPHESGYAADISAATQLKDISSMEK-k.........
H1KZJ0_9EURY/84-304              ............LGSIFSQIMEKLYLADYR----NGIAVVNKSIV-..............YGDHNGIKDTVLKVLEFG..LGVGDKVNIVEE---.......--KNYTRVETLCGVTFDNWLLGHGILPIPKYGGIVKFED..YEPVQFEGVINYKSTSVDPLEAFIMQ.....GKTDVLGFIENGEGYVPANFRVIPKEAEDKFERLLKKD---TLNCIL..SYGE..--DNV.LGMNVE.EDEIG.IALI.GGL..APVAALVERGYYVELNAASTIKKVSFMEK-v.........
H1KZJ0_9EURY/320-537             ............IKSVLSKMFNSMAKVNYDIDKKDGNVIVNVGYVG..............KEYYDDVLDILKEAYKKG..LGISNRFGIKEE---.......--DGLIKISTICASTLDGIFSSYGVPIIPCYGGILEVEE..DN-ERFIDIISYEGSSLDPHEVFFNK.....V---------DCETSILAGFREIPMCAREDLIDLVKAL---GWNGIK..EIGR..PNNEV.YGVSVE.KNMCG.VVTI.GGM..NPLTMIKEHEIPIKINALHEIVKFSELVE-y.........
F4BZP9_METCG/89-329              ............IGFVNTRIEEYMYKSNFDPCSGQGQVIANTSIVD..............KADAEEVLDMLGRAFDQG..YTISRRVLILDEGDAis..tleVPAGSLGLATVCSITMDGILMKKGIAVLTSFAGLAKIKE..KQPIEFTDLIAYAGSSLDPVKVFMGR.....KVTSVANAIRLGSGRVLANVREIPVAAAGHALELLEASRSAGFGGLI..KVGG..PAEPI.LGCPVA.AGKIG.IAFY.AGV..NGTVAAEEMGARMKTLPISMLVDYSRMTD-l.........
Q2FTS7_METHJ/83-316              ............IGFVISKLERLAFRSTFDPATSTGDVAYNLTIVP..............DEILEPVSQMFDKVRDAG..CSFFSGYSVIDRDPR.......VPSGHTGILTVCSITMDGVFQHNGIPVKVAYGGTIQIED..KKPVRFMNIIGYQGSTVDSLQLFLGA.....GLTSINQYINTGSGILLANVRQIPGAAEERSQTLIQEMQACGFRFPL..MMGK..--GRI.FNLLTD.PHRIS.LVSY.SGM..NSIGGAVEAGYKLKTEIGAGTIPFSRV---vdr.......
H3ZNZ7_THELI/85-326              .......igips-----IEIEKLITNSDYDIDKNKGKVMVNAIMVP..............KDKYDLVVPLLLDISKTN..VITSPLLAILDEKESiw..hfeVKEGHVGILGISSRTYDIIFQKNGICLQSTATGLYQLEN..NTPKGFMEIISHLGTTISPGELLIRG.....GYTSVHKVASTGSGYVTAAIKTFSSFLYEDTIKILEKLKKNNISGIA..EHSCviPENKR.VNIM-D.KNKGY.LVVY.GGA..NYFAPIVETGVSKKLEIARDLYDIQKMKK-p.........
Q8TSH4_METAC/8-248               ............IQFTSSRIRDLMYMTTFNPKKMDGDVILNLSVIE..............KKDLDDVLGIFKMVISSG..LSVTPYVKVISEGESig..nltVGKGKVGIGTVCSITIDGVLLKAGIPVHPKLGGVVQIRN..GIPIRFTDVLTYVSTTVDPLEVLMSQ.....GITSVSEMLRTGSGKVLANLREAPMVARDAIESTLSDLLDAGFSGIL..EVGE..PNTRV.LDIPIE.RDHLG.IVVI.GGT..NPMAVVQEYGIPIDTSAMSRLIPFKEMSR-i.........
Q6LZL7_METMP/316-533             ............VTPVLSKMLSKMQTINYDIEDKKGNVVVNTAKIP..............IEYKEEAINALKDSYENK..LAISDRLKVECD---.......--DKFLNAYTICSLTVDGVFLKNKIPVIPYYGGILEVKA..DK-KRFIEAIDYEGTSLDPHEVFFNK.....A---------DGKNYILAGIRKVPMSASEKLIELNEKL---GWNSII..EIGR..PNNDI.CGVRVE.KCMFG.ITTI.GGT..NPFANIRKNNIPVEMKTLHKSIDYSELTHY..........
A5FQT6_DEHSB/100-340             ............VGFVIDKIERLAYMTDFDLDNLSGMVPVNISFFA..............KDQFKPALRAMAQAYKAN..LCVSDLVCIAHEGDKis..ditVPEGQVAFATVCSIVINGTLLKAGIPMDSRFGGTLQFHQ..HKPWRFTDMIYYTGSSLDPSEIFIAS.....RMTSVSEVARRGEGKVLCNFREIPAVSLPLAEKIIAKLKNAGINGVL..VIGE..AGKSI.CEMPVG.LNKVG.MIMM.GGL..NPVASAVESNIPAASHAMSGLVPYSSFTS-y.........
A3CSY8_METMJ/86-318              ............LGFIISRLEQLAFRSTFDPATATGSVAYNLSFVR..............EEDLPGVTAAFDEVAAAG..YGFLNAYRIVDSDPR.......IPDGHAGIMTACSVTLDGVLQKMGIPTRLEYAGRIAVDE..NGSAGFLDLIGYRGTSVDPLHLFISA.....GLTSINRLVTTRAGVALANVRAVPAAARYRVEVTVGLMEKCGFTFPAggGIGE..-----.FNLPKH.PYRLS.VVAL.SGM..NMVGNAIEKGYAIKTEIGAGTVPFEKIAD-a.........
E3GY38_METFV/84-308              ............VDFIFSRFENMMYETTLNPKTGEGKVVVNISVIP..............----SEAFNMMKKIFHTG..LCVSPKVGLNKK---.......--NGKYEVKTICGTTVDGMLLNEGIPVIPKFGGLVEVED..FRPIKFTELIEYKKTSMTPLEAFATK.....ELTSVLDVVNEGKGKIPANFRIIPKSAKEKAINLFKKLRKIGINGLL..KIGE..--KKV.LGVPVD.DGMIG.IAIV.GGI..TPICAVHEAGYDIDIKVAEDLTEFKNLKT-i.........
D7EBR2_METEZ/12-252              ............VQFTLSKIVNLMFSTTYDPKTGKGDVIANVSIIN..............KHDLNRVLEIFKTAMMSG..LTVSPFIKILHEGESig..dltIKEGKIGLATMCSITIDGILLKRGILVNPKFGGLVQIEE..GSPVRFTDVLTYASTSIDPLEALMSQ.....EITSVTQMISTGSGKILANLREVPIAARYDIDHVLSDIMDAGLSGIL..EVGE..PNRKI.LDVPIE.RDHLG.IVVI.GGT..NPMAIVREHGIPIETNAMSTIVDITEMSDI..........
F6BCA0_METIK/320-537             ............IKSVLSKMFNNMAKVTYDINKEDGNVIVNVGYVE..............KKYYDDVVEILKEAYKKG..LGISDRFGIKEE---.......--DGLIKISTICASTLDGILSNYGIPIIPCYGGVLEIGE..EK-ERFIDIISYEGSSLDPHEVFFNK.....V---------DCETSILAGFREVPMCAREDLIDLVKVL---GWNGIK..EIGR..PNNEV.YGVSVE.KNMCG.VVTI.GGM..NPLAMIKEHEIPIEIKALHEIVKFSELVKY..........
A6UTI8_META3/83-311              ............IGSVFSQIMDKLYLSNFP-----TKVIINKTTI-..............EGDYAEIKNLALKVMEHG..YSIGDYMNISKECNAni...knDNDDLITVETLCSITFDNFLLKNGILSNPKYGGIIKFED..YEPAYFDGTIDFKKTSIDPLDAFISR.....GKTDILGIIENGEGYIPANFRVIPKSTKDKFKNLLNRD---LLNGVL..SYGE..--ENV.LGIDLN.ENEIG.VALV.GGL..CPICPAVELGHVVNIGAATSLTDLSLMEK-k.........
Q2LQG6_SYNAS/84-324              ............VGFLSAKIDTMTYQMNFDLNTASGKVVINVTLVE..............PGIFARSIPLVKKVYEKG..YAMGHLLTFLGPGETlg..yvtVPEGTIGIGTVCSITLNGVLLKHAIPTTSRFGGLLELQN..GKPLRFAEIIMYDGTSIDPLEIFIRS.....GMTNYIDAVQTGNGRIGASFREFPAESREMVEHLDRKMKRIGLGGLL..RIGM..PGQSL.LDIPVS.EGRVG.AIII.GGL..NPVSIMEETGVRLYSRALAGLIDFRKLFH-y.........
G0H4D6_METMI/316-533             ............VTPVLSKMLSKMQTINYDIEDKKGNVVVNTAKIP..............IEYKEEAINALKDSYENK..LAISDRLKVECD---.......--DKFLNAYTICSLTVDGVFLKNKIPVIPYYGGILEVKA..DK-KRFIEAIDYEGTSLDPHEVFFNK.....A---------DGKNYILAGIRKVPMSASEKLIELNEKL---GWNSII..EIGR..PNNDI.CGVRVE.KCMFG.ITTI.GGT..NPFANIRKNNIPVEMKTLHKSIDYSELTHY..........
O27611_METTH/332-561             ............VRFLLSKAWNLINRVDLNPEDLSGRVIANISLIS..............RDDLDYALEVIGQVLSERpeFSTLPMIGVTDE---.......--GGMAGIATVCSLTLDGVLIKSGIMSTPKYGGLLEVGG..RAP-RFVELTAYSGSSLDPHEIYVSK.....NMTAVLEAL-NGQGRVLASLREVPYLARDHAEGLIEELSEAGFS-VL..KIGV..PGEIL.YNARVE.KYHAG.IVTP.GGL..NPLAAVREAGVEIRMKAIERLMDLREFR--yv........
D9PU67_METTM/84-310              ............VDFIFSKFESMIYRTSFNPDTLEGKVVVNTSRIS..............----PESIETLKYVMKNG..FCLSPRVRLEEH---.......--DGEFVISTICGTTVDGLLLMNGIPVIPQFGGLVRFEE..SRPVNFRELIAYKKTSMTPLEAFTSE.....NMTSVLDVIENGEGTVPANLRLIPGTAREEAMKLFRKLEGADISGVL..KVGD..PGEDV.LGVPVA.DGMVG.VAII.GGI..TPLCAIQEAGYMAEIKLAENLIDFRNLE--pl........
A6VJR1_METM7/81-300              ............IGSVFSQVIEKLYLSDFP-----SKVLINTAKF-..............EGDYKTIKELVLKSFEAG..YSVGDYLNIKKK---.......--GYSVFVETLCSITFDNFLLKNGIIPTPEYGGIVKFED..YEPVNFEGVIEFKSTSIDPLVAFIMQ.....GKTDVIGVIENGEGLVPANFRVIPKSSEKQFENILKKD---MLNSVL..AYGT..--ENV.LGMNLN.PEQIG.VVLV.GGL..TPLCIPHESGYTADISAATQLKDISSMEK-k.........
A0B6Y5_METTP/84-309              ............IGFVNTLIEEYMLRTTFDF--ASGDLVANISLID..............RNDLERALEIMEMVAESG..YS-GDLVRVHHK---.......--DDCAEIGTVCSITVDGLLLRAGIPVNTTFAGVLEIRN..GEPCRFSDLIAYAGTSIDPMRAFMAR.....RIARVMDAVRSGSGKVLANVREVPVSALEDAMRVLDRA--RSIVGRI..AVGA..PGDDV.LGCPVA.PGRVG.IAIC.AGV..NAPVAVAECGIRIRTCPISTLIPCGEMSR-i.........
Q58GH8_METTL/320-538             ............VKPVLSKMLSLMERVTYDIEEKKGDIIVNTGCVD..............KKYKKEVFDALRESYEKK..LTISDRVGIETK---.......--DGQIFIHTLCSLTIDGIILKNEIPVIPCYGGVLELRS..GKGNRFIDVIAYRGTSLDPHEVFFNK.....T---------DGEKNILAGIREAPMSAKDHIAQLNEKL---EWNGII..EIGR..PNNDI.SGVRVE.KGMIG.FTTV.GGI..NPLVLIKKRGVPIEINALHKTMNYSDLIH-f.........
A5UN44_METS3/83-312              ............VDFIYSKFEEMIYLTSFNYMNRAGNVVVNTSTI-..............--YDEEAFNIIKDVFKSG..LCVSPYINLKEGN--.......-SKEEIQIKTICGTTIDGILLNEGIPTIPLYGGLVKIRD..YVPTKFTELISYKKTSVTPLDAFVAP.....GMTSVLDVINTGTGTIPANLRLIPSVGRERALNIINKLEKIGIGGVM..AVSE..EGKNM.LGVPVP.EGMVG.IAVS.GGV..TPFCAAQELGYDIDIKIAEEIEGFETLS--pi........
C6A4T1_THESM/104-345             .......igips-----IEIEKLITDSDYDINKNKGKIMVNAIMVP..............KDKYDAVVPLLLDISKTN..VITSPLLAILDEKDSiw..hfeVKEGYVGILGISSRTYDIIFQKSGICLQSTATGLYHLEN..NIPKGFVEIISHLGTTISPGELLIRG.....GYTSVHKVASTGSGYVTAAIKTFSSFRYDDTLRILEKLKKNNISGVA..EHSS..IIPEN.KRVNVM.DKNKGyLVVY.GGA..NYFAPIVETGISKKLEIARDLYEIQKMKE-p.........
F4BX01_METCG/4-234               ...........l-VFTLARIENLMHQVSFDPAGMKGKIITNTTTVR..............KEALDETLAVFYDTINSG..LAVSPMIKVIEG---.......--KGRIKIKTACSLTLCAVMLKHGIPVHPKGGGLVEVVE..REPTRFTDMLMYWATTVDPIDVLTAQ.....GLMNITGMMRTGNGRILGNLHEAPMLARDKIEDVLEALAQAGFAGVL..ELGQ..PNMNV.LGVSVE.RDHVG.LALV.GGT..NLMAAAKECQIDVMHESISDLTDISELKHI..........
F8F2H0_SPICH/85-325              ............VGYMSARIDQMTYTMDFDLPRRKGTVVINLAIIK..............QEEFLRYLPQVELVFEKG..YAMGTLVSFLHEGERlg..sytIPTGHIGFCTVCSVTLNGVFLKYGIPTRSLFSGLLQLEQ..GQARRFVELISYDGTSIDPLQLFIRG.....KMTDYMGAIRDGNGRIGAGFREIPGESYQLAQDLARQLQDIGLGAFL..KIGR..PSRDL.LNVPVH.EGCCG.LIVI.GGL..NPVAVFEESGISVSYNALAGYMEYNQLF--hh........
A5UN44_METS3/331-559             ...........p--FLLSKSWNLIQKVNFDVETRKGDIIVNVSYIN..............KDSLDKAIYIMKETYESN.pKYINPYYQLVEHPT-.......-DYTKIGIATICSLSIDGLLINNGIMSNPKYGGLLELNE..-SP-LFIDLISYNGSSVDPHKIFIAK.....NMTSITRNI--GSNKILASLKEIPYISRDYAVHLLNILKNIGFS-IY..KIGK..PRELT.YNAKVD.NYNFG.VVAG.SGL..NLIAALKEKGIDVEVKAIAKLMKFEKMER-l.........
H8I6V2_METCZ/8-248               ...........m-MFTKARIEEIMYSVTFNPKTREGDIVVNLSVVD..............KKDLDEVLDIFKQVMYSG..LSVCSYVKLFDEGEAfs..gyaIPEGKAGIATACSITIDGVFLKHGIPVRPKFGGIVQVKD..RQPVRFTDMIRYDCTTIDPLEVLMSQ.....ELTSIRDMMRTGSGKILANFRELPMTAKDDADHVLNRLLTAGFYGIL..EVGE..PNTPV.LGVDVD.RDHFG.VIIT.GGT..NPMAAVQESGIPILTKAIKGTLDFHEMKK-l.........
D5VS72_METIM/82-300              ...........l-GNIYSNILEKVILSDYQ----AGLVVVNRSIV-..............YTDYEKALSLIKKVYENG..LAIGDRVGIVDR---.......--EKYIELYTLCSLNLDGLLVKNGIPVYHICGGIVKYEN..YEPVEFKEIIKYKATSIDPLLAFIER.....KKTDVLGIIENGEGYLPANFRVIGANYRERFERIIKKL-----DGII..SYGS..--ENV.LGLDVG.EEHIG.IVMI.GGL..SPIAPFVEKDIPTEIIPMSSIVRLSSLHK-l.........
A9A6B8_METM6/81-300              ............IGSVFSQVIEKLYLSDFP-----SKVLINTAKF-..............EGDYKTVKDLVLKSFEAG..YSVGDYLNIKKK---.......--GNSVFVETLCSITFDNFLLKNGIIPTPEYGGIVKFED..YEPVNFEGVIEFKSSSIDPLVAFIMQ.....GKTDVIGVIENGEGLVPANFRVIPKSSEKQFENILKKD---MLNSVL..AYGT..--ENV.LGMNLN.PEQIG.VVLV.GGL..TPLCIPHESGYTADISAATQLKDISSMEK-k.........
D5E8G5_METMS/85-321              ............LDFVITRIEDLIYRTDYDPVKKQGNVIVNVSYVD..............KDDFEKTAGLMRGAV--D..YSISPRVGVFEEDSEd....ifVPAGKVGIATVCSITFDGILLRHGIPVKPNFGGILSVEN..NEPVVFKDLISYRGTSIDPIKIFLMR.....QSTSVTGLLQSGSGTILANMRSIPQSAVGDASLLFQQLHESDIGGLL..AMDN..ESGNV.LGAPVD.VGLSG.IVVS.AGV..NALAVVEEYGIDVTTRPVSTIMDYGTMKT-l.........
A3CSS1_METMJ/5-245               ............LKFTNHRIEEYALKVTYRPEDDTGKIIYNLSLIE..............SRDLEFALSIMKEAHKRG..ITISDRLLVAGPGGQva..gytVPDGRHAVCTMCSITLDALLLQRGIPASPIGGGIVEVDG..RVAQRFTSMILYRDTTLDPLEVLISQ.....EATSILDVMRHGKGNILANIRECHMEAEQLLGTVLDELSAIGFSGIL..DVGA..PNVPL.LGVPVS.PQYIG.VAMV.GGT..NAMAAVREAGKPVVTRALKGLIDIREMDY-l.........
Q12VW5_METBU/8-248               ............VQFTSSRIEDLMYRTTFDPVNMTGELIVNQSLVK..............EKDLEAVLEVYNLVIRSG..LSVSPFLKIIKSGETig..dlkIAQGDVGIATVCSITIDGVLLKGGVMINPRFGGVVQIKN..GQPVRFTDVVTYASTTIDPLEVLMSQ.....DITSVTKMLRTGSGKILANLREAPLVARDDIDHILSDLMEAGLSGIM..EVGE..PNTRV.LDVPVE.RDHLG.VVVI.GGT..NPMAMAKEQGFEISTSAMSALIGIDSMKHI..........
Q8PVJ4_METMA/8-248               ............IQFTSSRIRDLMYRTTFDPKKMDGDIILNLSLID..............KKDLDDVLGIFKMVISSG..LSVTPYVKVISEGESig..dmtIEKGKVGIGTVCSITIDGVLLKAGIPVNPKLGGVVQIRN..GIPVRFTDVLTYVSTTVDPLEILMSQ.....GITSVSEMLRTGSGKVLANLREAPMVARDEIESNLSDLLDAGFSGIL..EVGE..PNTRV.LDVPIE.RDHLG.IVVI.GGT..NPMAVVQEYGIPIDTSAMSRLISFKEMSR-i.........
Q2NHI2_METST/324-553             ............VSFVLNKIYNLLSTVNFDIESGEGDVIVNVSFVD..............RNNLDTSLEILSKMYKSKpeFCIGNRYSLVDG---.......-PDNKVGIATICSLTIDGILTKHGISSFPKYSGILDIYG..NS-RRFIELISYKGSSVDPHEIFINK.....NMCELN--VSGDSCKILASVHSVPYIARDKTVDILDKLGEYGFE-VL..NIGK..PNEYT.YNAKIE.KYHFG.YVLA.GGL..NPIAAIKKEGIPTDVKSIETMKNFNSFEE-f.........
E1RE54_METP4/5-245               ............LKFINHQIEENAIKVTYNPTENTGKVIYNISLIK..............SEDLDYSIDIYNEAFHAG..LCLSDRVRFAEQGCKfg..dykIPAGHTGIITICSLTLDALLYKKGVPLNPIGGGLVEVRK..MTPRRFTAMVRYEYTTIDPITVMISH.....GNTSVQEVIHNGNGTITANIRECHMEAEPSVFEVLDDLNEAGFSGIL..DVGV..PNTSL.LGVPVT.PNYMG.IAMV.GGT..NPAAAIMESGRGVEINSMKGLIAISEI---gyl.......
D3E025_METRM/333-561             ...........p--FILTKSLNRVNQVDYDIETGHGNIVSNISYLQ..............KEDLDDAISIMKKTYKAL.pKYMNSHFSIVDHPDD.......--KSKVGIATVCSLSIDGILIKNGIMSTPQYGGLLELGK..--PPLFVEMISYNGSSIDPHKIFIFK.....DLTQIA--KRKNPKKILASIKEVPYIARPETEEILEKISKEGFS-IF..KVGK..PRELV.YNAKVD.NYNFG.IVTG.SGL..NLIAAIKEKGINIEAKAVETVLPIEDMS--li........
D3SUV1_NATMM/83-191              ..........le--QIRARIAALTSRVSYDPLEDTGALVTSAAYLD..............EDAVDEALDLVASLESLP..LGPIP-IALEDSAES.......-EPGDVRLLVPSSITLDGVLLAHGVNADLATAGLLEYEP..--------------------------.....-----------------------------------------------..----..-----.------.-----.----.---..------------------------------vavse.....
D3S1I8_FERPA/83-324              ...........i-GYSISRVHECVFYSDFDVESGEGKVVANLAIFP..............REYLEEVLDMFYRCWKKG..LTFSDKVIVDENIPF.......IEENEVGLYYISSFTLDAILYRNGIVSSPRFAGSIEISN..FNFVRFTQVIGLEESSITALDLFIQRmysdkDEESISNLLEKGEGEVYGMYREIPFVAREKTIEILEKLKEYGISPLY..VIGE..LDKSV.CGIPPKgVNKVG.LVCV.GPS..TPVGILRALKVPIRVHISSEIIEFSKFKS-l.........
A6VJR1_METM7/316-533             ............VTPVLSKMLSKMQAVNYDIEDKKGNVVVNTARVP..............IEYKEEAINALKDSYENK..LAISDRLKIEYD---.......--GEFLNAYTICSLTVDGVFLKNKIPVIPYYGGILEVKT..DK-KRFIEAIDYEGTSLDPHEVFFNK.....A---------DGKNYILAGIRKVPMSATEKLIELNEKL---GWNSII..EIGR..PNNDI.CGVRVE.KCMFG.ITTI.GGT..NPFANMRKNNIPVEMKTLHRSIDYSELTHY..........
F7XPA1_METZD/85-324              ............LGFVINRIDELIYLTDYDLNEKKGNVIVNISHID..............KNDIDASIEIMKYAADSD..IGISPKIRIFEEDSDsn...itVPPGSVAVATLCSITFDGLLLKGGIPVEPYYGGTLQIKD..RDPVKFLDLISYNGTSIDPIKIFMSR.....RSTSVLNIMDTGEGTMLANVRYIPTSAREKADEILKKAGLSDMAGTI..TIGG..SGEEL.FGAPAD.IGKSG.IPIF.VGV..NTIAAVQEAGIKVNTYPISTILDYSTMYK-l.........
D3SUV6_NATMM/199-332             ......aahgga----------------------------------..............------------------..---------------.......---------------------------------------..--IRRFTDVIGDERATVDMVSLLIEA.....RRTTVGSALAGEPGLLVADNREFPLAKYDRAHELAVAT-RRQLGGVI..DVRR..PREPGpFPWDEP.GWAFA.SLTC.VGLseCLIARCVEEGIATEWETLARVHDRAD----lq........
D5VS72_METIM/316-533             ............IKTALSKMINLMAHVNYDIYEKDGDVIVNIGYID..............KKYLDEALDILKEAYSKG..LGISDRFGYEVL---.......--KDKVKIKTICAVTLDGIINNLGVPIIPKYGGILEVKE..EE-MRFIDIIKYSGTSLDPHEIFFNK.....V---------DCETTFLAGFREIHRICREELERIIELL---EWNGIK..CIGE..PNNEL.AGVKVN.KDMCG.VITI.GGA..NPLSFLNENEISVEIKAMHEITKFSELIS-y.........
D3SJ14_DEHSG/90-330              ............VGFVIDKIERLAYMTDFDLDNLSGMVPVNISFFA..............KDQFKPALRAMAQAYKAN..LCVSDLVCIAHEGDKis..ditVPEGQVAFATVCSIVINGTLLKAGIPMDSRFGGTLQFHQ..HKPWRFTDMIYYTGSSLDPSEIFIAS.....RMTSVSEVARRGEGKVLCNFREIPAVSLPLAEKIIAKLKNAGINGVL..VIGE..AGKSI.CEMPVG.LNKVG.MIMM.GGL..NPVASAVESNIPAASHAMSGLVPYSSFTS-y.........
B5YGF1_THEYD/80-318              ............VGFIINKIETLSYLSDFDINAMKGRLILNITYIH..............KNKFRKALKAMENVFTSP..YVMSDRILVLEKDSEn....ilVPEDHVCIGTVCSVTLNAILLKHGIPIISRFGGVLEIRE..GESYRFGALISYDGTSLDPLEIFIRG.....KMTDVLGTIKNGFGRVLASFREVPIVCLDKVKEIYSIMQKRGFQGIM..MFGE..PNQPL.LDIPVG.MDRVG.IIVV.GGL..NPIAAIEENNIQTYTTAISVLYDCRELV--vf........
D3SUV6_NATMM/83-195              ...........v-EQVRERLADLTSHVTYNPETDDGDVVVGTVTVP..............ATNRSDVESIIAAIDDSP..LG--PAATALESVER.......DGEEFLEIAAPSSVTIDGVLLNEGIDTDLETTGVVEYHA..--------------------------.....-----------------------------------------------..----..-----.------.-----.----.---..------------------------------dpesvpydd.
#=GC SS_cons                     ............---HHHHHHHHHCC---BTTTTB-EEEEEEEEEE..............GGGHHHHHHHHHHHHHTT..-SSSSEEEEEE----.......--SSEEEEEEE-CHHHHHHHHCTT--EEEEEEEEEEE-S..S--EEEEEEEESTT-SS-HHHHCGGG.....-----------SSSEEEEEEEEEETTTHHHHHHHHHHH---T-TTEE..EE--..TT--B.TTB---.TTEEE.EEEE.-TT..HHHHHHHHTT---EEEEEEEEEEGGGSEE-..........
#=GC seq_cons                    ............lshlhS+l.phhapssaD.pptpGpVllNhohlt..............cpphccslclhccshcsG..huloshlplhcc............psplsltTlCSlTlDGlLL+sGIPspPpaGGllclcs..tpPh+Ft-lIsYcuTSlDPlclFhsp.....shTsVhthhpsGpGplLANhRplPhsuc-chpcllccL.t.uhsGll..plGc..sspsl.hGlsVs.psphG.lshh.GGl..NPlushpEpGlslchpshpslhchpphpp.h.........
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