#=GF ID   DUF1890
#=GF AC   PF09001.6
#=GF DE   Domain of unknown function (DUF1890)
#=GF AU   Mistry J, Sammut SJ
#=GF SE   pdb_1kjn
#=GF GA   25.00 25.00;
#=GF TC   136.10 135.90;
#=GF NC   24.70 19.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR012033;
#=GF CC   This domain is found in a set of hypothetical archaeal proteins.
#=GF SQ   40
#=GS Q2FRW8_METHJ/11-151  AC Q2FRW8.1
#=GS B8GI79_METPE/15-155  AC B8GI79.1
#=GS G7WND6_METH6/15-155  AC G7WND6.1
#=GS G0H3N9_METMI/4-144   AC G0H3N9.1
#=GS Q8TUD9_METAC/7-147   AC Q8TUD9.1
#=GS D5VTC6_METIM/3-142   AC D5VTC6.1
#=GS Q46E53_METBF/7-147   AC Q46E53.1
#=GS D3S6C7_METSF/4-144   AC D3S6C7.1
#=GS H1KWF2_9EURY/4-144   AC H1KWF2.1
#=GS A7IA47_METB6/19-159  AC A7IA47.1
#=GS A0B5R6_METTP/7-148   AC A0B5R6.1
#=GS F6D465_METSW/5-148   AC F6D465.1
#=GS A9A7Q8_METM6/1-141   AC A9A7Q8.1
#=GS F4BV71_METCG/1-131   AC F4BV71.1
#=GS E1RIN5_METP4/11-151  AC E1RIN5.1
#=GS Q8PX08_METMA/7-147   AC Q8PX08.1
#=GS O26871_METTH/10-153  AC O26871.1
#=GS O26871_METTH/10-153  DR PDB; 1KJN B; 10-153;
#=GS O26871_METTH/10-153  DR PDB; 1KJN A; 10-153;
#=GS A6USJ9_METVS/4-144   AC A6USJ9.1
#=GS A6UVE1_META3/4-144   AC A6UVE1.1
#=GS B9AD46_METSM/4-147   AC B9AD46.1
#=GS A3CWT6_METMJ/10-150  AC A3CWT6.1
#=GS B8GH97_METPE/12-153  AC B8GH97.1
#=GS F6BA72_METIK/4-144   AC F6BA72.1
#=GS D2ZRJ0_METSM/4-147   AC D2ZRJ0.1
#=GS Y452_METJA/5-145     AC Q57894.1
#=GS A5UJD1_METS3/4-147   AC A5UJD1.1
#=GS D7DTT0_METV3/4-144   AC D7DTT0.1
#=GS D9PX18_METTM/4-147   AC D9PX18.1
#=GS H1Z466_9EURY/11-152  AC H1Z466.1
#=GS A4FY99_METM5/4-144   AC A4FY99.1
#=GS G6FHK7_9EURY/14-154  AC G6FHK7.1
#=GS E3GXM9_METFV/4-145   AC E3GXM9.1
#=GS A2SPZ3_METLZ/5-146   AC A2SPZ3.1
#=GS A6VK08_METM7/4-144   AC A6VK08.1
#=GS D3E4S8_METRM/4-147   AC D3E4S8.1
#=GS Q6LZC8_METMP/4-144   AC Q6LZC8.1
#=GS F0TCE6_METSL/5-148   AC F0TCE6.1
#=GS F8AMX0_METOI/4-144   AC F8AMX0.1
#=GS C9RE55_METVM/5-145   AC C9RE55.1
#=GS Q8TY95_METKA/3-137   AC Q8TY95.1
Q2FRW8_METHJ/11-151             VLVMGCPKVPVQTSLVLYLSNRMKKAGIRTIIAGTPSARQLIRVADPDGHYTMEM..KDLDATIAALAKGdlTVTESYVFVHNDAGVSYAATM.QSLTNQP.VMAIIFGEE.AEQIAQEIT.....FPCTVIAEPATHNPMSLKNRLEEA-a..
B8GI79_METPE/15-155             LILLGCPQVPVQTSLAIYLCHALKAHGVLPTIAGTTSARKLIDVADPEGHYIGTS..IDLDACIAAIAEKerDFDEIFVFVHNDGGVSYAGTM.SAISSGR.LIAVIYGEH.AEEVAATIT.....FPCEKVVAKAVHNPMPLVHKLKEVL...
G7WND6_METH6/15-155             LILLGCPEVPVQTSIALYLAYRLRERGDEVVVAGTGAALKLTKLADPLGHYLGET..TNIDRCIASISEGkaDFDQCFAFAHSDAGITYAGTI.SYISRAL.LFVLIFGRS.AEELAETVE.....FDCRKLVAKAVHDPLPLKRLLDEVI...
G0H3N9_METMI/4-144              MIILGCPEPPVLVPAFMFLLNMLKNKGHELIVSANPAALKLIESADPEKYYLTGIgfQPIDEGLKTRA--..EVDHIIGFAHNDAAVNYIVTY.KMTHNVN.TSAIVFGKEfNEELLQILT....eNGVTAEMARAFHNPTPLNVKIKKM-f..
Q8TUD9_METAC/7-147              LLMMGCPEIPIQTSIALYLSHKLTNLGFDVTVAGTEAATRLLKVSDSDGYYAKKL..VNLDKTMEDIIEKrsDFDICFAFMHNDAGMTYAATM.SALSQAK.LYSIVFGRH.ADELAETIE.....FDGEKIVSKDVHNPLRLKNRLDKIV...
D5VTC6_METIM/3-142              LILLGCPEPPAMIPSALYLIAKLRK-LKDIVIAGNHAALKLLDVSDVERHYLKGVacIDIDEGLRGLE--..GVEKIVSFVHNDGGVSYTVTY.KNKYKKE.CLAILFGRKiNEEFKKTLE....eNDIKVFPVRAFHNPYPLVKTIDKII...
Q46E53_METBF/7-147              LLMMGCPEVPIQTSIALYLSHNLTKLGFDVTVAGTTAARKLLKVSDSDGYYVKRL..VDLDKTIVDIIEKrtDFDMCFAFMHNDAGMTYATTM.SSISQAM.MYSIIFGRN.AEALAETIE.....FDCEKIVAQDFHNPVRLKNKLDKVM...
D3S6C7_METSF/4-144              LVIVGCPEPPALIPSVLYLINQLKKRGFGVVIAANPAALKLLEVADDDKYYLKGVgaVDIDEGLRGIE--..GIDKIIAFVHNDGGVSYTATY.KAKYGKD.TYAIVFGRQiNNDYVETLK....nSGIEVYTARAFHNPIPIVNRIKQIL...
H1KWF2_9EURY/4-144              LILLGCPEPPVLVPSFIYLTNMLKKKGYEVFVSANPAALRLVETADPEKLYIKNVgfQEIDEGLKEAF--..DVDYIISFVHNDAGVSYTITY.MHKYKAK.TIGIVFGREmKEDFVNTLK....eNGVETYFVRAFHNPTPIVVTLKRIL...
A7IA47_METB6/19-159             VLVLGCPQVPVQTSVALYLADKLSVAGIAPVIAGNKAAITLLVVADPKRHYLKEV..MDLDRAIAQISDKkrDFDLCFVFIHNDAGVSYAATM.AAISKAK.IFPVIYGEH.WEEMAAQIT.....FPCTKIAVKAVHNPLPIKKIIDEV-a..
A0B5R6_METTP/7-148              LLLMGCPEVPVQMSLVLYLSGALRDKGLKVFIAGNPAALNLARVADRKRCYLGRL..IELERTIADIVEGrrSFGICFAFAHNDAGITYAATVrALLPEAR.FFVIIFGRN.AEELAGTVD.....FDAEKIAERAVHNPLGLKKKIDEVL...
F6D465_METSW/5-148              LILLGCPEAPSQTPMAVYATYKLTKMGYDVTVASTPSAMKLIEVSDPETFYIKSK..IDIESCLENLESG..AFDLLVGFVHKDAAVSYFVTF.YHILNTT.SIALVFEKD.PDLLEKFEKmvkenTDAEIVAVRAYHNPTPMKVKFDRA-i..
A9A7Q8_METM6/1-141              MIILGCPEPPVLIPAFMFLLNMLKNKGHEIIVSANPAALKLIESVDPEKYYLKGIgfQPIDEGLKNKA--..EVDYIFGFVHNDAAVNYIITY.KMTHNVD.ASAIVFGKEfNDELLQILA....eNGVNAEMARAFHNPTPLNVKIKKM-f..
F4BV71_METCG/1-131              ----------MQISIVIYLAHKLKKEGWDVTVAGTNAPIKLLKTADPEGYYVQKT..ADLDWIIQEIVEKkmDFDACFAFMHSDAGMAYGATF.SAISKAV.HYAVVFGKN.AEALGESID.....YPTEKIVAKATHNPGPLKSKIDKVI...
E1RIN5_METP4/11-151             LLVMGCPQVPVQTPAVLYISYKLKEEGYKPVAAGTPAADMIIKYSDPGLYYIGEL..KNIDSEVARIVDEgeNYDLCFVFIHNDSGVAYAATM.NEILECE.VIPVVFGKE.YDEMVKLID.....FSSRIISAEAVHNPKPLIKEIDRVM...
Q8PX08_METMA/7-147              LLMMGCPEVPIQTSIALYLSHKLTQSGFDVTVAGTNAATKLLKISDSDGYYAKKL..VDLDKTLEDIIEKraDFDICFAFMHNDSGVTYAATV.SAISQVR.MYSIVFGRH.AEELAQTIE.....FDCEKIVTQDVHNPVRLKNKLDKIM...
O26871_METTH/10-153             LMVLGCPESPVQIPLAIYTSHKLKKKGFRVTVTANPAALRLVQVADPEGIYTDEM..VDLESCINELAEG..DYEFLAGFVPNDAAAAYLVTF.AGILNTE.TLAIIFDRD.ADVLEELVNeimetLDAEIIAARAHHNPAPLRVRIDRFM...
#=GR O26871_METTH/10-153  SS    EEE---S-STTHHHHHHHHHHHHHCTTEEEEEEE-HHHHHHHHHHSTT-SS-SEE..EEHHHHHHH--TT..S-SEEEEEESSHHHHHHHHHH.HHHH-SE.EEEEEE-S-.HHHHHHHHHHHHHH---EEEEE--SS--HHHHHHHHHHH...
A6USJ9_METVS/4-144              MIILGCPEPPVLIPSFMNLLSLLKNKGHEIVVSANPAALKLIESADPEKYYLKGVgfQSIDEGLKEKI--..PVDYIFGFAHNDAAVNYIITY.KMVYNID.ASAIVFGKDfENELVKILS....dNGVKAEMAKAFHNPTPLNVKIKKII...
A6UVE1_META3/4-144              MILLGCPEPPVLIPSCISLINMLKEKGCEVVISANPAALKLIESADPEKYYLKDVgaQSIDGGLKNKF--..PVDLIIGMAHNDAAVNYIITY.KSVYDAK.TVAMVFGKNiNNELIEDLM....dEEIPCQTAKAFHNPTPVIVKLKKIV...
B9AD46_METSM/4-147              LILLGCPETPSQTPMSIYASYKLSEKGYDVTIAANPAASKLVKVSDPEKYYIQEM..VDLDDCLANVQEG..EYDLLLGFVHKDAAASYFVTF.YQLLQTK.SIALVFEKD.SELLKEYTEivsenTDAEVISVRAFHNPNPIKVNLDKVL...
A3CWT6_METMJ/10-150             LILLGCPQVPVQTSMALYLVHGLKEQGIRPVIAGTQAARKLMEVADPDRHYVSEM..TDLDAAIDEITGKqrDFDLCFVFIHNDSGVAYAGTM.AYISKAR.VYALLFGEH.AEELAGEIE.....FPCEVVAAKAVHNPMPLKRKLDEVM...
B8GH97_METPE/12-153             LIILGCPEASAQQALALHVAHNLKKRGAEVLIAGNPAVLNLLKVSDPEKHYITNT..MTLEQCIGDVIENkrDCDLCVVFAHNDAAITYAATMrYLLPERK.MVVIVFGKD.PGPLADAIQ.....FPCEIIVDRAVHNPMKLKTMINRV-f..
F6BA72_METIK/4-144              LVLLGCPEPPVLVPSFIYLTNMLKKKGCEVFVSANPAALKLVETADPEKLYIKNVgfQEIDEGLKEAF--..DVDYIISFVHNDAGVSYTITY.MHKYKAK.TIGIVFGREmKEDFVNTLK....eNGVEAYFVRAFHNPTPIVVTLKRIL...
D2ZRJ0_METSM/4-147              LILLGCPETPSQTPMSIYASYKLSEKGYDVTIAANPAASKLVKVSDPEKYYIQEM..VDLDDCLANVQEG..EYDLLLGFVHKDAAASYFVTF.YQLLQTK.SIALVFEKD.SELLKEYTEivsenTDAEVISVRAFHNPNPIKVNLDKVL...
Y452_METJA/5-145                LVIVGCPEPPALIPSVLYLTNQLKKKGFNVIIAANPAALKLLEVADDDKYYLKGVgaVDIDGGLRGIE--..GINKIISFVHNDGGVSYTVTY.KAKYNKP.TYAIVFGRQiNKDYVETLK....nSNIGVYTARAFHNPMPIVNRIKEIL...
A5UJD1_METS3/4-147              LILLGCPETPSQTPMSIYASYKLSEKGYDVTIAANPAASKLVKVSDPEKYYIQEM..VDLDDCLANVQEG..EYDLLLGFVHKDAAASYFVTF.YQLLQTK.SIALVFEKD.SELLKEYTEivsenTDAEVISVRAFHNPNPIKVNLDKVL...
D7DTT0_METV3/4-144              LILLGCPEPPLLIPSFMFLLNLLKNKGHQVYVAGNPSALKLIESADPEHHYLKGVgfQPIDNGLKEKF--..DVDYIFGLTHNDAGVNYIITY.KMVYNKD.TSALVFGTGdLESLSKILN....eNGVENKSMRAFHNPTPINVMLKRI-f..
D9PX18_METTM/4-147              LMILGCPESPVQVPLAIYTSHKLRKKGFSVTLTANPAAIRLVQVADPEGVYTGEL..TDLDSCLNELSEG..DYEFLVGFVPNDAATAYLATF.AGILNTE.TLAVVFERD.ADTLEKLVDavmegTEAEVIAARAHHNPAPLRVRIDRFL...
H1Z466_9EURY/11-152             LLVLGCPQVPTQTAAAMYLAYKLRNAGIRPVIAANPAARMLMKYADPEKHYIDEL..HDLDKMIGDLVEKrqEFSLCFVFVHNDSGLSYAASM.NIILNGGvVIPVIFGKE.IESLKEGIN.....FECSVISGRAEHNPKPLINAME---sgi
A4FY99_METM5/4-144              MIILGCPEPPVLIPSFMFLLNMLKNKGHEIIVSANPAALKLIESADPEKHYLKGIgfQPIDEGFKIKA--..EVDHIFGFAHNDAAVNYIITY.KMTHNVD.TSAIVFGKEfKDELVQLLT....eNGVNAQMARAFHNPTPLNVKLKKM-f..
G6FHK7_9EURY/14-154             VLVLGCPQVPVQTAVALYLMHGLRRLGVRPIVAGNPAARMLIDVSDPLHHYAGEM..VDLDTFIADMAAGrrKHDYYIVFAHNDAGVTYAATV.QSISGKK.VIMIIYGEN.FQAIADRVD.....FPAEKIMAKAVHNPMPMKKKIDEVL...
E3GXM9_METFV/4-145              LIMLGCPEYPIQTPLTIYTSYLLKIKNCKVSIAGNPAALNLVKISDPERRYIDKL..LNIDSH--EIEKN..KWDYLIGFISNDASATYFITF.NEILNVG.SLSIVFNED.KKELKELVEtikhnTNSKIIQARARHNPKPLVKKIDAFM...
A2SPZ3_METLZ/5-146              LILIGCPQIPVQSPLVLYIADFLQDAGHHPVVAANPSAKQLVKTSDPKSHYVSEY..KDVEKAIGELADGtvQYPLIISLIHNDAGLTYTATTsAVAPKSL.LISVLFGEH.AYDLAEEIE.....YPTEKVVAPVTHNTRPLLIKLDEVL...
A6VK08_METM7/4-144              MIILGCPEPPVLVPSFMFLLNMLKNKGHEIIVSANPAALKLIESVDPEKYYLKGIgfQPIDEGLKNKA--..EVDYIFGFAHNDAAVNYIITY.KMTHNVD.TSAIVFGKEfKDELVQILT....eNGVNAQMARAFHNPTPLNVKLKKI-f..
D3E4S8_METRM/4-147              LVLLGCPEAPSQTPIGLYASYKLGQMGYDVTVSSNPAAGKILDISDPEGVYVKKR..VDIEKCLDEIEEG..DYDLLVGCVHKDAAATFFITY.YHILKCK.ALALVFSRD.AEEVAEFADmvessTDADIIAVRAFHNPNPIKVRFDKY-l..
Q6LZC8_METMP/4-144              MIILGCPEPPVLVPAFMFLLNMLKNKGHELIVSANPAALKLIESADPEKYYLTGIgfQPIDEGLKTRT--..EVDHIIGFAHNDAAVNYIVTY.KMTHNVN.TSAIVFGKEfNEELLQILT....eNGVNAEMARAFHNPTPLNVKIKKM-f..
F0TCE6_METSL/5-148              LILLGCPEAPSQTPLAVYTTYKLKEIGYEVTVASTPSAMKLLEVSDPEGFYVTNK..VDIESCLENLEEK..EYDLLFGFVHKDAAAAYFVTF.YHILNTK.SVALVFEKD.IDLLEKFIKdvqdsTDSEIVSARAYHNPTPLRVKVDR--yi.
F8AMX0_METOI/4-144              MIILGCPEPPVLIPSFIYFLNLLKNSGHEVFVSANPAALKLIETADPEKYYLKGVgfQNIDEGLKNKF--..DVDIIIGFAHNDAAVNYIITY.KTVYNSK.TMALVFGKNiNEEFVKTLE....eENIKTFTARAFHNPTPVIVQLKR--lk.
C9RE55_METVM/5-145              LIVVGCPEPPALIPSVLYLINQLKKKGFNVVVAVNHAALKLLEIADDDKYYLKGVgaVDIDEGLRGIE--..GIDRIITFVHNDGGVSYTATY.KVKYNKP.TYAIVFGRKiNSDHVEALK....nSNINVYTARAFHNPLPIVNKIKEIL...
Q8TY95_METKA/3-137              VVSLGCPKIPPKISSAIYACYRYDD---RALVLSTEAGCKLLEYADPEKEYVDET..RTYEKYLEDPD--..AAGILLAFVTNDTELQIAVTL.KEVSEPD.DARAVCTEEfEDRLEDCGF.....LTAPVTGRRWKHDPKRWVKAVEDVL...
#=GC SS_cons                    EEE---S-STTHHHHHHHHHHHHHCTTEEEEEEE-HHHHHHHHHHSTT-SS-SEE..EEHHHHHHH--TT..S-SEEEEEESSHHHHHHHHHH.HHHH-SE.EEEEEE-S-.HHHHHHHHHHHHHH---EEEEE--SS--HHHHHHHHHHH...
#=GC seq_cons                   LllLGCPEsPlQsPhslYLsptL+ccGacVslAuNPAAhKLlcluDPE+aYlppl..h-lDcslpslttt..-hDhlhuFlHNDAuloYhsTa.ptlhpsc.shAlVFG+c.s--Lschlc....thsschlsuRAaHNPtPLps+l-+lh...
//