GenomeNet

Database: Pfam
Entry: DUF1922
LinkDB: DUF1922
Original site: DUF1922 
#=GF ID   DUF1922
#=GF AC   PF09082.9
#=GF DE   Domain of unknown function (DUF1922)
#=GF AU   Sammut SJ
#=GF SE   pdb_1gh9
#=GF GA   20.70 20.70;
#=GF TC   20.70 20.80;
#=GF NC   20.60 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   11017201
#=GF RT   Structural proteomics of an archaeon. 
#=GF RA   Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort
#=GF RA   JR, Booth V, Mackereth CD, Saridakis V, Ekiel I, Kozlov G,
#=GF RA   Maxwell KL, Wu N, McIntosh LP, Gehring K, Kennedy MA, Davidson
#=GF RA   AR, Pai EF, Gerstein M, Edwards AM, Arrowsmith CH; 
#=GF RL   Nat Struct Biol 2000;7:903-909.
#=GF DR   INTERPRO; IPR015166;
#=GF DR   SCOP; 1gh9; fa;
#=GF CC   Members of this family consist of a beta-sheet region followed
#=GF CC   by an alpha-helix and an unstructured C-terminus. The beta-sheet
#=GF CC   region contains a CXCX...XCXC sequence with Cys residues located
#=GF CC   in two proximal loops and pointing towards each other. This
#=GF CC   precise function of this set of bacterial proteins is, as yet,
#=GF CC   unknown [1].
#=GF SQ   51
#=GS A0A151BS91_9ARCH/4-75  AC A0A151BS91.1
#=GS A0A0M0BRL5_9ARCH/2-68  AC A0A0M0BRL5.1
#=GS A0A166FHX3_9EURY/2-68  AC A0A166FHX3.1
#=GS A0A0Q1AVG7_9EURY/2-63  AC A0A0Q1AVG7.1
#=GS A0A101XJL2_9CREN/3-67  AC A0A101XJL2.1
#=GS G7WKM8_METH6/2-69      AC G7WKM8.1
#=GS D5PF81_9MYCO/171-224   AC D5PF81.1
#=GS A0A101XMV5_9CREN/2-61  AC A0A101XMV5.1
#=GS L0HIF0_METFS/2-70      AC L0HIF0.1
#=GS A0A0S8KA65_9BACT/2-65  AC A0A0S8KA65.1
#=GS B8GE38_METPE/2-70      AC B8GE38.1
#=GS A0A0N8WAC5_9EURY/2-69  AC A0A0N8WAC5.1
#=GS Q2NI59_METST/3-69      AC Q2NI59.1
#=GS U6EF32_9EURY/2-68      AC U6EF32.1
#=GS F4BW42_METCG/1-65      AC F4BW42.1
#=GS E3GWV7_METFV/2-68      AC E3GWV7.1
#=GS A7I836_METB6/4-73      AC A7I836.1
#=GS F0T8Q0_METLA/2-68      AC F0T8Q0.1
#=GS F6D2E8_METPW/2-68      AC F6D2E8.1
#=GS A0A0M9E528_9DELT/2-56  AC A0A0M9E528.1
#=GS A0A101X890_9CREN/3-62  AC A0A101X890.1
#=GS R9SN16_9EURY/2-68      AC R9SN16.1
#=GS A0A0N8PWB3_9ARCH/2-64  AC A0A0N8PWB3.1
#=GS D7EA10_METEZ/4-74      AC D7EA10.1
#=GS A0A117SMT3_9CREN/2-61  AC A0A117SMT3.1
#=GS E1RDL2_METP4/12-78     AC E1RDL2.1
#=GS I7KCQ6_METBM/2-72      AC I7KCQ6.1
#=GS A0A101X6Q7_9CREN/2-61  AC A0A101X6Q7.1
#=GS F2KNB2_ARCVS/2-66      AC F2KNB2.1
#=GS D3TBQ6_ACIB4/1-42      AC D3TBQ6.1
#=GS H1Z128_9EURY/2-68      AC H1Z128.1
#=GS A0A166ESQ7_9EURY/2-68  AC A0A166ESQ7.1
#=GS A0A101WVC4_9CREN/2-61  AC A0A101WVC4.1
#=GS A0A166C180_9EURY/2-68  AC A0A166C180.1
#=GS A5UM02_METS3/7-73      AC A5UM02.1
#=GS A0A0F2L4N0_9CREN/2-61  AC A0A0F2L4N0.1
#=GS E1QQM3_VULDI/2-61      AC E1QQM3.1
#=GS PA84_METTH/2-68        AC O27252.1
#=GS PA84_METTH/2-68        DR PDB; 1GH9 A; 2-68;
#=GS A0A109UVP9_9EURY/2-68  AC A0A109UVP9.1
#=GS A0A101IYY5_9EURY/2-67  AC A0A101IYY5.1
#=GS Q12UN9_METBU/7-75      AC Q12UN9.1
#=GS A0A126R1L4_9EURY/2-68  AC A0A126R1L4.1
#=GS A0A151E092_9EURY/7-70  AC A0A151E092.1
#=GS A0A166CUA1_9EURY/2-68  AC A0A166CUA1.1
#=GS A0A0Q1AGM2_9EURY/2-72  AC A0A0Q1AGM2.1
#=GS D3E077_METRM/2-68      AC D3E077.1
#=GS A8MDT3_CALMQ/3-62      AC A8MDT3.1
#=GS A0A101DQX7_9EURY/2-68  AC A0A101DQX7.1
#=GS A3CUS1_METMJ/2-72      AC A3CUS1.1
#=GS A0A0P9G6S1_9ARCH/2-65  AC A0A0P9G6S1.1
#=GS A2ST71_METLZ/8-73      AC A2ST71.1
A0A151BS91_9ARCH/4-75             ..............YIVFACPrCGVPRYAAEGQKTA..RCfY.CGVLIRL.DpaE.TRILLRAENARAAREAVEeyKMRRRIRGKT------rserp.........
A0A0M0BRL5_9ARCH/2-68             ..............YVVVNCPrCGSIMLAKTVYKTR..SC.PhCGYRAEL.R..R.LRVLGRASSSTEAVALIQ..ALKEKSVGK-------gnrrl.........
A0A166FHX3_9EURY/2-68             ..............YIIFRCD.CGRVLYAKEGVATR..KC.V.CGKSIKT.K..S.RRIFKKIETSEEASEAVR..QMQEEIHGKTGFTTAN..............
A0A0Q1AVG7_9EURY/2-63             ..............FLVIRCPgCRTFTYVDRFQQWK..LCaV.CGEAINV.R..R.APAYVEVDDYHTAESIVS..QLE-------------kylhqa........
A0A101XJL2_9CREN/3-67             .......ylvlixp------R.CGRPSAARTGSRSH..EC.PyCGFMFPV.A..N.ASLVGKASSGREAREIIR..QLLD------------sgksdsgk......
G7WKM8_METH6/2-69                 ..............YLIFRCSgCGRHLYAEEGSATR..TC.P.CGKRIKL.G..Q.VKVLSRARDEREAGDLVR..ALQVEGRGMTGFSPA-g.............
D5PF81_9MYCO/171-224              .............i------E.CGTMLYADTDNRTT..TC.PeCGQTIDVeK..N.QRETAKSRDLRTTTEILE..----------------lltnid........
A0A101XMV5_9CREN/2-61             ..............YLVVSCPkCGNYSVVKDNVKTH..QC.PyCGYVMRI.E..E.AIIIARAKNGREAREIIL..KLK-------------tpre..........
L0HIF0_METFS/2-70                 ..............YLIIRCPqCVTFTYVDNFQRWK..LCpT.CGHAYEV.S..K.APMYLEVQDHHEAEHIVR..QMEKHLH---------ankkkdfsa.....
A0A0S8KA65_9BACT/2-65             ...........tir---FRCE.CGRVLMASDDQSGRegQC.PaCGEIVTI.P..Q.AEVLDRKESEQDSSEK--..----------------efedeaaegeas..
B8GE38_METPE/2-70                 ............fh--VLRCPgCSTFTYVDRFERWK..LChV.CGEVINA.K..R.APVYLDVRDYRDAEDVVV..QLEE------------flhaagrddlsr..
A0A0N8WAC5_9EURY/2-69             ..............YLIFRCAgCGRHLYAEESAATR..TC.P.CGKRIKI.D..T.VKVISRAEDEREAGDLVR..ELQMGGREMTGFSPA-g.............
Q2NI59_METST/3-69                 ..............YLIYRCD.CGRVLYSKETTKTK..KC.T.CGKTLNV.K..K.RRILKIAQSSTQATETVQ..QMQEEIYGGSIFRTAN..............
U6EF32_9EURY/2-68                 ..............YLVFRCD.CGRAVYAREGVRQK..KC.V.CGKNLNV.K..E.RRILAKTQDAQDAAEKVQ..ELQEEKYGGAYFTTAN..............
F4BW42_METCG/1-65                 ..............--MFRCS.CGRHLYSPDDAKTR..TC.P.CGKRTAL.S..R.VRILATAPDARAAGEIVR..RLQLGDSGLTGFSQA-k.............
E3GWV7_METFV/2-68                 ..............YLIFRCD.CGRALYVHESNSVK..RC.V.CGRLIKV.K..S.RRILGKVNSFEEASEIVR..KLQEEKYGKAVLMTAD..............
A7I836_METB6/4-73                 ..............YLILRCPgCRAFSYVDRFQKWK..LC.PaCGHAFEV.A..K.VPAYLEVGDYHDAEHIIR..QMEKHL----------hthkkkdftpe...
F0T8Q0_METLA/2-68                 ..............YIVFRCD.CGRAVYSKQGTATK..KC.V.CGKTLKV.K..E.RRILAMTEEAEQASDKVR..ELQEEKYGGAIFTTAD..............
F6D2E8_METPW/2-68                 ..............YLIFRCD.CGRTMYSKEEVARK..KC.V.CGKNLKV.K..E.RRILAKTDNAESASQMVR..KFQEEKYGGLQFTTAD..............
A0A0M9E528_9DELT/2-56             ...........itv----TCS.CGKTYHVKDSYAGKkaKC.T.CGKVLKI.S..DpPQILEKDPKLE-------..----------------ekdaekitf.....
A0A101X890_9CREN/3-62             ..............YLVVRCPrCSMPSAVRLGSLSH..TC.PyCGTRFKV.N..E.VNIVARARNGREASELVR..RML-------------aqgr..........
R9SN16_9EURY/2-68                 ..............YLIFRCD.CGRVLYAKKGQATR..KC.V.CGKVLKV.K..E.RRIFKKVATREEASKAVQ..DMQEEIHGFKGFQTAN..............
A0A0N8PWB3_9ARCH/2-64             ..............YLVIICHnCGQFLLAKTGQKTR..RC.PyCETRLVL.D..K.AKKVAHTKTAQEASSVIR..ALKRK-----------nsvgs.........
D7EA10_METEZ/4-74                 yavivctkcrqhaq-------.----IIENDNKKTT..KC.QnCGSTLNV.D..K.LRFFYQCDNLDDAVSART..KVQSQIQGQEQIQ---dis...........
A0A117SMT3_9CREN/2-61             ..............YLVVSCPkCGNYSVVRDNVKTH..QC.PyCGYVMRI.E..E.AIIIARAKNGREAREMIL..KLK-------------tpre..........
E1RDL2_METP4/12-78                ..............YLIIRCPgCLSFTYVDKYQKWK..LCpV.CSETINP.G..K.VQVYLDVETPSEAEIITR..QLQK------------ylkekrkkdl....
I7KCQ6_METBM/2-72                 ..............YLVIRCPgCKTFTYVDRYQRWR..LC.PmCGEAINI.G..K.APVYLDADDFQDAECVVE..QLES------------ylhrtgkkdltesd
A0A101X6Q7_9CREN/2-61             ..............YLVVSCPkCGNYSVVRDNVKTH..QC.PyCGYVMRI.E..E.AIIIARAKNGREAREIIL..KLK-------------tpre..........
F2KNB2_ARCVS/2-66                 ..............FVVFRCRkCGRYLYAKESTKTK..MC.V.CGCRNNL.K..R.VRKLARAETELEAGEIVR..RLQG------------sgtefdsld.....
D3TBQ6_ACIB4/1-42                 ..............--MYRCVrCGRPLTSELGVQQL..EC.E.CGSRMFY.K..E.RPNMKK------------..----------------ivya..........
H1Z128_9EURY/2-68                 ..............YLIIRCPgCQAFSYADRYQKYK..LC.PdCGYTMNI.K..S.CPVYLDVKTFPQAEAIVK..ELE-------------aylhkrnkkel...
A0A166ESQ7_9EURY/2-68             ..............YLIFRCD.CGRALYSKEGVVTR..KC.V.CGKSLKV.K..Q.RRIFKKVETAEDASEAVR..QMQEENYGGVDFKTAD..............
A0A101WVC4_9CREN/2-61             ..............YLVVSCPkCGNYSVVRDNVKTH..QC.PyCGYVMRI.E..E.AIIIARAKNGREAREIIL..KLK-------------tpre..........
A0A166C180_9EURY/2-68             ..............YFIFRCD.CGRVLYAKKGVATR..KC.V.CGKTLKV.K..Q.RRIFKKVATREEASLAVQ..KMQDEIYGNTDFKLA-s.............
A5UM02_METS3/7-73                 ..............YFIFRCD.CGRVLYAKEGVATR..KC.V.CGKTIKV.K..Q.RRIFKKVETREEASLAVQ..EMQDEIYGNTDFKRA-s.............
A0A0F2L4N0_9CREN/2-61             ..............YLIISCPkCGNYSIVKDSTKTH..QC.PyCGYVMHL.E..E.AVILARAKNGKEAREIIL..RL--------------kipre.........
E1QQM3_VULDI/2-61                 ..............YLIIACPrCGNYSVVRDTAKTH..QC.PyCGYVMRI.E..E.ASIIARAKNGKEARELIL..KLK-------------tpre..........
PA84_METTH/2-68                   ..............YIIFRCD.CGRALYSREGAKTR..KC.V.CGRTVNV.K..D.RRIFGRADDFEEASELVR..KLQEEKYGSCHFTNP-s.............
#=GR PA84_METTH/2-68        SS    ..............EEEEEET.TS--EEEETT-SEE..EE.T.TTEEEE-.-..S.SS-BS--SSHHHHHHHHH..HHSS---S-TTSS-T-T.............
A0A109UVP9_9EURY/2-68             ..............YFIIRCD.CGRALYAKEGVATR..KC.V.CGKTLKV.K..S.RRIFKKVATREEASEAVQ..EMQDKIYGNTGFMRA-s.............
A0A101IYY5_9EURY/2-67             ..............YLVIRCPgCRSFTYMDHLQQRK..LCpV.CGEIISS.Q..K.VPVYIEVQTYAEADQIVS..QLEE------------ylrktqqgd.....
Q12UN9_METBU/7-75                 ...viacpkcrksa-------.---QLIEDKDAKTT..KC.QlCGTNLHI.R..K.LRVFHTGEDIEEARAVRT..KVQAQLLGEKQST---tms...........
A0A126R1L4_9EURY/2-68             ..............YLIFRCD.CGRVLYAKKGVATR..KC.T.CGKTIKV.K..S.RRILQKVETAEDASYAVQ..KMQEEIYGSTSFRTAD..............
A0A151E092_9EURY/7-70             .vcpnckyvkgvnl-------.---------SSKTT..KC.TrCGKILQL.K..K.VRIFYETELQEKLRQVVG..LMNAEMEGKR------dsflk.........
A0A166CUA1_9EURY/2-68             ..............YYIFRCD.CGRALYSKEGVKTR..KC.V.CGKTIKV.K..S.RRIFKKVETADQASEAVR..KMQEENYENTFFKTAD..............
A0A0Q1AGM2_9EURY/2-72             ..............YMVIRCTgCRTFTYVDRFQRWK..LCpV.CGAAIDV.A..R.APAYLDVPSHSEAESLVQ..KLEK------------fldetgksdlnrde
D3E077_METRM/2-68                 ..............YVIFRCD.CGRVLYAKQGVKTR..KC.T.CGKTIKV.K..S.RRILQKVETANDASLAVQ..KMQEEIYGGTAFKTAD..............
A8MDT3_CALMQ/3-62                 ..............YLIVRCPrCSMPSAVRLGSVSH..MC.PyCGSRFRI.S..E.GTIITKARNGREASELIR..RI--------------ltqsh.........
A0A101DQX7_9EURY/2-68             ..............YLVFRCD.CGRALYAREGVKTR..KC.V.CGKTVKV.K..S.RRILGKVESFQDAAYMVR..KLQEEKYGPGGFL---kkk...........
A3CUS1_METMJ/2-72                 ..............YLVIRCPgCKTFNYVDRYQRWR..LC.PmCGEVINV.Q..R.APVYLDVDDFLDAEQVVE..QLES------------ylhqtgkkdlteqd
A0A0P9G6S1_9ARCH/2-65             ..............YMVIVCYtCGRFLLAKVGQKTR..RC.PyCEARVVL.E..K.ARRVAYAKSAQEASNIIR..TLKKSK----------tfpqq.........
A2ST71_METLZ/8-73                 ..........svig-----CMkCRRRIVADLSYATK..TC.I.CGNKIDL.T..Q.TKLLAVCESADEAGELLR..RMQTAKN---------sgftsank......
#=GC SS_cons                      ..............EEEEEET.TS--EEEETT-SEE..EE.T.TTEEEE-.-..S.SS-BS--SSHHHHHHHHH..HHSS---S-TTSS-T-T.............
#=GC seq_cons                     ..............YllhRCs.CGphhYsccss+T+..pC.s.CGpslcl.c..c.tplht+scstc-ApplVp..phpp............t.............
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