GenomeNet

Database: Pfam
Entry: DUF1922
LinkDB: DUF1922
Original site: DUF1922 
#=GF ID   DUF1922
#=GF AC   PF09082.8
#=GF DE   Domain of unknown function (DUF1922)
#=GF AU   Sammut SJ
#=GF SE   pdb_1gh9
#=GF GA   20.70 20.70;
#=GF TC   20.70 20.90;
#=GF NC   20.60 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   11017201
#=GF RT   Structural proteomics of an archaeon. 
#=GF RA   Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort
#=GF RA   JR, Booth V, Mackereth CD, Saridakis V, Ekiel I, Kozlov G,
#=GF RA   Maxwell KL, Wu N, McIntosh LP, Gehring K, Kennedy MA, Davidson
#=GF RA   AR, Pai EF, Gerstein M, Edwards AM, Arrowsmith CH; 
#=GF RL   Nat Struct Biol 2000;7:903-909.
#=GF DR   INTERPRO; IPR015166;
#=GF DR   SCOP; 1gh9; fa;
#=GF CC   Members of this family consist of a beta-sheet region followed
#=GF CC   by an alpha-helix and an unstructured C-terminus. The beta-sheet
#=GF CC   region contains a CXCX...XCXC sequence with Cys residues located
#=GF CC   in two proximal loops and pointing towards each other. This
#=GF CC   precise function of this set of bacterial proteins is, as yet,
#=GF CC   unknown [1].
#=GF SQ   28
#=GS D7EA10_METEZ/4-74      AC D7EA10.1
#=GS A0A0M0BRL5_9ARCH/2-68  AC A0A0M0BRL5.1
#=GS D5PF81_9MYCO/171-224   AC D5PF81.1
#=GS G7WKM8_METH6/2-69      AC G7WKM8.1
#=GS E1RDL2_METP4/12-78     AC E1RDL2.1
#=GS F2KNB2_ARCVS/2-66      AC F2KNB2.1
#=GS D3TBQ6_ACIB4/1-42      AC D3TBQ6.1
#=GS L0HIF0_METFS/2-70      AC L0HIF0.1
#=GS H1Z128_9EURY/2-68      AC H1Z128.1
#=GS B8GE38_METPE/2-70      AC B8GE38.1
#=GS Q2NI59_METST/3-69      AC Q2NI59.1
#=GS U6EF32_9EURY/2-68      AC U6EF32.1
#=GS F4BW42_METCG/1-65      AC F4BW42.1
#=GS E3GWV7_METFV/2-68      AC E3GWV7.1
#=GS A5UM02_METS3/7-73      AC A5UM02.1
#=GS E1QQM3_VULDI/2-61      AC E1QQM3.1
#=GS PA84_METTH/2-68        AC O27252.1
#=GS PA84_METTH/2-68        DR PDB; 1GH9 A; 2-68;
#=GS A7I836_METB6/4-73      AC A7I836.1
#=GS A0A0E3SQG3_METMT/7-74  AC A0A0E3SQG3.1
#=GS Q12UN9_METBU/7-75      AC Q12UN9.1
#=GS F0T8Q0_METLA/2-68      AC F0T8Q0.1
#=GS F6D2E8_METPW/2-68      AC F6D2E8.1
#=GS D3E077_METRM/2-68      AC D3E077.1
#=GS A8MDT3_CALMQ/3-62      AC A8MDT3.1
#=GS A3CUS1_METMJ/2-72      AC A3CUS1.1
#=GS A0A0M9E528_9DELT/2-56  AC A0A0M9E528.1
#=GS A2ST71_METLZ/8-73      AC A2ST71.1
#=GS R9SN16_9EURY/2-68      AC R9SN16.1
D7EA10_METEZ/4-74                 yavivctkcrqhaq-------.----IIENDNKKTT..KC.QnCGSTLNV.DK.LRFFYQCDNLDDAVSARTKVQSQIQGQEQIQ---dis...........
A0A0M0BRL5_9ARCH/2-68             ..............YVVVNCPrCGSIMLAKTVYKTR..SC.PhCGYRAEL.RR.LRVLGRASSSTEAVALIQALKEKSVGK-------gnrrl.........
D5PF81_9MYCO/171-224              .............i------E.CGTMLYADTDNRTT..TC.PeCGQTIDVeKN.QRETAKSRDLRTTTEILE----------------lltnid........
G7WKM8_METH6/2-69                 ..............YLIFRCSgCGRHLYAEEGSATR..TC.P.CGKRIKL.GQ.VKVLSRARDEREAGDLVRALQVEGRGMTGFSPA-g.............
E1RDL2_METP4/12-78                ..............YLIIRCPgCLSFTYVDKYQKWK..LCpV.CSETINP.GK.VQVYLDVETPSEAEIITRQLQK------------ylkekrkkdl....
F2KNB2_ARCVS/2-66                 ..............FVVFRCRkCGRYLYAKESTKTK..MC.V.CGCRNNL.KR.VRKLARAETELEAGEIVRRLQG------------sgtefdsld.....
D3TBQ6_ACIB4/1-42                 ..............--MYRCVrCGRPLTSELGVQQL..EC.E.CGSRMFY.KE.RPNMKK----------------------------ivya..........
L0HIF0_METFS/2-70                 ..............YLIIRCPqCVTFTYVDNFQRWK..LCpT.CGHAYEV.SK.APMYLEVQDHHEAEHIVRQMEKHLH---------ankkkdfsa.....
H1Z128_9EURY/2-68                 ..............YLIIRCPgCQAFSYADRYQKYK..LC.PdCGYTMNI.KS.CPVYLDVKTFPQAEAIVKELE-------------aylhkrnkkel...
B8GE38_METPE/2-70                 ............fh--VLRCPgCSTFTYVDRFERWK..LChV.CGEVINA.KR.APVYLDVRDYRDAEDVVVQLEE------------flhaagrddlsr..
Q2NI59_METST/3-69                 ..............YLIYRCD.CGRVLYSKETTKTK..KC.T.CGKTLNV.KK.RRILKIAQSSTQATETVQQMQEEIYGGSIFRTAN..............
U6EF32_9EURY/2-68                 ..............YLVFRCD.CGRAVYAREGVRQK..KC.V.CGKNLNV.KE.RRILAKTQDAQDAAEKVQELQEEKYGGAYFTTAN..............
F4BW42_METCG/1-65                 ..............--MFRCS.CGRHLYSPDDAKTR..TC.P.CGKRTAL.SR.VRILATAPDARAAGEIVRRLQLGDSGLTGFSQA-k.............
E3GWV7_METFV/2-68                 ..............YLIFRCD.CGRALYVHESNSVK..RC.V.CGRLIKV.KS.RRILGKVNSFEEASEIVRKLQEEKYGKAVLMTAD..............
A5UM02_METS3/7-73                 ..............YFIFRCD.CGRVLYAKEGVATR..KC.V.CGKTIKV.KQ.RRIFKKVETREEASLAVQEMQDEIYGNTDFKRA-s.............
E1QQM3_VULDI/2-61                 ..............YLIIACPrCGNYSVVRDTAKTH..QC.PyCGYVMRI.EE.ASIIARAKNGKEARELILKLK-------------tpre..........
PA84_METTH/2-68                   ..............YIIFRCD.CGRALYSREGAKTR..KC.V.CGRTVNV.KD.RRIFGRADDFEEASELVRKLQEEKYGSCHFTNP-s.............
#=GR PA84_METTH/2-68        SS    ..............EEEEEET.TS--EEEETT-SEE..EE.T.TTEEEE-.-S.SS-BS--SSHHHHHHHHHHHSS---S-TTSS-T-T.............
A7I836_METB6/4-73                 ..............YLILRCPgCRAFSYVDRFQKWK..LC.PaCGHAFEV.AK.VPAYLEVGDYHDAEHIIRQMEKHL----------hthkkkdftpe...
A0A0E3SQG3_METMT/7-74             ...vivcpkcrksa-------.---QLIEQKGAKTT..RC.QrCGATLQT.RK.LRVFHTTDNLEEAIAVRTRLQAEVLGK-------gyetmk........
Q12UN9_METBU/7-75                 ...viacpkcrksa-------.---QLIEDKDAKTT..KC.QlCGTNLHI.RK.LRVFHTGEDIEEARAVRTKVQAQLLGEKQST---tms...........
F0T8Q0_METLA/2-68                 ..............YIVFRCD.CGRAVYSKQGTATK..KC.V.CGKTLKV.KE.RRILAMTEEAEQASDKVRELQEEKYGGAIFTTAD..............
F6D2E8_METPW/2-68                 ..............YLIFRCD.CGRTMYSKEEVARK..KC.V.CGKNLKV.KE.RRILAKTDNAESASQMVRKFQEEKYGGLQFTTAD..............
D3E077_METRM/2-68                 ..............YVIFRCD.CGRVLYAKQGVKTR..KC.T.CGKTIKV.KS.RRILQKVETANDASLAVQKMQEEIYGGTAFKTAD..............
A8MDT3_CALMQ/3-62                 ..............YLIVRCPrCSMPSAVRLGSVSH..MC.PyCGSRFRI.SE.GTIITKARNGREASELIRRI--------------ltqsh.........
A3CUS1_METMJ/2-72                 ..............YLVIRCPgCKTFNYVDRYQRWR..LC.PmCGEVINV.QR.APVYLDVDDFLDAEQVVEQLES------------ylhqtgkkdlteqd
A0A0M9E528_9DELT/2-56             ...........itv----TCS.CGKTYHVKDSYAGKkaKC.T.CGKVLKI.SDpPQILEKDPKLE-----------------------ekdaekitf.....
A2ST71_METLZ/8-73                 ..........svig-----CMkCRRRIVADLSYATK..TC.I.CGNKIDL.TQ.TKLLAVCESADEAGELLRRMQTAKN---------sgftsank......
R9SN16_9EURY/2-68                 ..............YLIFRCD.CGRVLYAKKGQATR..KC.V.CGKVLKV.KE.RRIFKKVATREEASKAVQDMQEEIHGFKGFQTAN..............
#=GC SS_cons                      ..............EEEEEET.TS--EEEETT-SEE..EE.T.TTEEEE-.-S.SS-BS--SSHHHHHHHHHHHSS---S-TTSS-T-T.............
#=GC seq_cons                     ..............YllhRCs.CGphlYsccss+o+..pC.s.CGcslpl.+c.t+lhtcscshc-AspllpclQpt.........................
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