#=GF ID DUF1933
#=GF AC PF09147.5
#=GF DE Domain of unknown function (DUF1933)
#=GF AU Sammut SJ
#=GF SE pdb_1q15
#=GF GA 20.50 20.50;
#=GF TC 20.50 20.60;
#=GF NC 20.20 19.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 12890666
#=GF RT Crystal structure of carbapenam synthetase (CarA).
#=GF RA Miller MT, Gerratana B, Stapon A, Townsend CA, Rosenzweig AC;
#=GF RL J Biol Chem. 2003;278:40996-41002.
#=GF DR INTERPRO; IPR015230;
#=GF DR SCOP; 1q15; fa;
#=GF CC Members of this family are predominantly found in carbapenam
#=GF CC synthetase, and are composed of two antiparallel six-stranded
#=GF CC beta-sheets that form a sandwich, flanked on each side by two
#=GF CC alpha-helices. Their exact function has not, as yet, been
#=GF CC determined [1].
#=GF SQ 6
#=GS Q9XB61_ERWCA/3-203 AC Q9XB61.1
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q19 A; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q15 D; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q15 B; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q15 A; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q19 C; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q19 B; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q15 C; 3-203;
#=GS Q9XB61_ERWCA/3-203 DR PDB; 1Q19 D; 3-203;
#=GS F5HGM6_PHOLL/3-201 AC F5HGM6.1
#=GS Q8KM13_PHOLM/3-201 AC Q8KM13.1
#=GS E6WK62_PANSA/4-204 AC E6WK62.1
#=GS C6CGN7_DICZE/3-204 AC C6CGN7.1
#=GS Q2NVG4_SODGM/4-196 AC Q2NVG4.1
Q9XB61_ERWCA/3-203 ...............................NSFCVVYKGSDTDINNIQRDF.DGKGEALSNGYLFIEQNGHYQKCEMERGTAYLI..GSLYNRTFLIGLAGVWEGEA.YLANDAELLALLFTRLGANALALAEGDFCF.FI.DEPN.G.ELTVITESRGFSPVHVVQ...GK.K.AWM.TN.SLKLVT..A.AEGEGALWFEEEA..LVCQSLM..R..ADTYTPVKNAQRLKPGAVHVLTHDSEGYSFVESRTL.......................................................
#=GR Q9XB61_ERWCA/3-203 SS ...............................--EEEEET--HHHHHHHHCCS.-EEEEEETTEEEEEETT--EEEEEETTEEEEEE..S--S-HHHHHHHHTTT-GGG.GG--HHHHHHHHHHHH-GGGGGG--SSEEE.EE.EETT.S.EEEEEE-SSSSS-EEEEE...SS.S.EEE.ES.-HHHHH..H.HH-TTSS-B--HH..HHSS-S-..-..-TT--SBTTEEEE-SSEEEEEEE-TTS-EEEEEEES.......................................................
F5HGM6_PHOLL/3-201 ...............................SEFCFVKYGFDKNLNKLINEF.--QFDELSTGTILFRSTTKVSKFKSERYTAFLI..GNIYNISTIRSILGKIEGRS.SVLSDVEILLLSRDKFGNSIISIAEGDYCL.FI.EDKK.G.NIEVITESRGLNLVNLVQ...TD.L.IWI.TN.SLKIVG..K.VEGDKAFDFKPES..EVIKNSL..K..PDNFSPIRNVSRLKPGTINKLTFDEQRYLHLEVEYV.......................................................
Q8KM13_PHOLM/3-201 ...............................SEFCFVKYGFDKNLNKLINEF.--QFDELSTGTILFRSTTKVSKFKSERYTAFLI..GNIYNISTIRSILGKIEGRS.SVLSDVEILLLSRDKFGNSIISIAEGDYCL.FI.EDKK.G.NIEVITESRGLNLVNLVQ...TD.L.IWI.TN.SLKIVG..K.VEGDKAFDFKPES..EVIKNSL..K..PDNFSPIRNVSRLKPGTINKLTFDEQRYLHLEVEYV.......................................................
E6WK62_PANSA/4-204 ...............................NGFCFLFKSK-KNHKFKRHPFpGGHIINLSLGELYISTEANFQVSTDSKHSAYLI..GSIYNRNFLVEIASMWESHA.YVFNDSELLITLYSRLGQSALTLAEGDFNF.II.EEKN.E.RLHLFSDSQGLSTAYLVE...SK.F.TWL.TN.TLKVVS..F.AEGEDALQFACES..LVCQSEL..R..PDNYSPVTNATRFKPGSYVILSRDREHYIQSDI---ntl....................................................
C6CGN7_DICZE/3-204 .............................hg--FCIARGDACLNIKKDVTGL.PLKIENLQNGYLFIGDKSPFAKMVTDNETLYLI..GTINNRRLLEGLAGRYDASA.WSLSDIELLHTIFLYLGTHALSLAEGSFFF.FK.ENKK.G.ELILLTDPNGFMPVHVIH...DHtA.LWI.TD.RLKFVG..Y.VVQKGIFDFMPED..KVIQHVL..H..SDTFTPIKNAIRLKPGSINQIKKDMQGYEYLGSD--ni.....................................................
Q2NVG4_SODGM/4-196 ...............................NDFCIIHGNINKDISLLAHCC.SGNIEMLRNGCLFTGRKTPVQSYRFTTGSAYLI..GSLRNKRLLRHLATHFTGGV.PVVNGAEILYQISTQLGSAALGLAEGDFCF.FI.EDRN.G.TLTLLTDACGQNPVYLVN...AG.D.RWI.TD.KLKLIS..A.LHDH---DIQHDP..QAGETAV..S..TGC-----HIQRILPGTLNVFRFSNADYQVCESRQL.......................................................
#=GC SS_cons ...............................--EEEEET--HHHHHHHHCCS.-EEEEEETTEEEEEETT--EEEEEETTEEEEEE..S--S-HHHHHHHHTTT-GGG.GG--HHHHHHHHHHHH-GGGGGG--SSEEE.EE.EETT.S.EEEEEE-SSSSS-EEEEE...SS.S.EEE.ES.-HHHHH..H.HH-TTSS-B--HH..HHSS-S-..-..-TT--SBTTEEEE-SSEEEEEEE-TTS-EEEEEEES.......................................................
#=GC seq_cons ...............................spFChl+tuhsKNlsplhpsF.shph-pLSsGpLahpspophpKhcs-+tTAYLI..GoIYN+shLculAG+aEGcu..VlsDsElLhhlhs+LGsuALoLAEGDFCF.FI.E-Kp.G.pLpllT-SpGhssVaLVp...sc.h.hWI.TN.oLKlVu..t.lEG-tAhDFpsEu..pVhpssL..+..sDsaoPl+NspRLKPGolNhLoaDppcY.alEsc.l.......................................................
//
