GenomeNet

Database: Pfam
Entry: DUF1938
LinkDB: DUF1938
Original site: DUF1938 
#=GF ID   DUF1938
#=GF AC   PF09153.5
#=GF DE   Domain of unknown function (DUF1938)
#=GF AU   Sammut SJ
#=GF SE   pdb_1mgt
#=GF GA   22.10 22.10;
#=GF TC   24.80 94.00;
#=GF NC   20.50 19.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   10497033
#=GF RT   Hyperthermostable protein structure maintained by intra and
#=GF RT   inter-helix ion-pairs in archaeal O6-methylguanine-DNA
#=GF RT   methyltransferase. 
#=GF RA   Hashimoto H, Inoue T, Nishioka M, Fujiwara S, Takagi M, Imanaka
#=GF RA   T, Kai Y; 
#=GF RL   J Mol Biol. 1999;292:707-716.
#=GF DR   INTERPRO; IPR015236;
#=GF DR   SCOP; 1mgt; fa;
#=GF CC   Members of this family, which are predominantly found in the
#=GF CC   archaeal protein O6-alkylguanine-DNA alkyltransferase, adopt a
#=GF CC   secondary structure consisting of a three stranded antiparallel
#=GF CC   beta-sheet and three alpha helices. Their exact function has
#=GF CC   not, as yet, been defined, though it has been postulated that
#=GF CC   they confer thermostability to the archaeal protein [1].
#=GF SQ   13
#=GS G2M2A0_9EURY/1-85  AC G2M2A0.1
#=GS OGT_PYRFU/2-90     AC Q8TZV2.1
#=GS OGT_THEGJ/1-85     AC C5A3L5.1
#=GS F8AIH4_PYRYC/1-86  AC F8AIH4.1
#=GS OGT_PYRHO/1-86     AC O59499.2
#=GS B6YXZ4_THEON/1-86  AC B6YXZ4.1
#=GS OGT_THESM/1-86     AC C6A382.1
#=GS OGT_THEBM/1-86     AC F0LIT8.1
#=GS OGT_PYRSN/1-87     AC F4HK38.1
#=GS G0HLY8_THES4/1-85  AC G0HLY8.1
#=GS OGT_PYRAB/1-86     AC Q9V1N7.1
#=GS OGT_PYRKO/1-85     AC O74023.1
#=GS OGT_PYRKO/1-85     DR PDB; 1MGT A; 1-85;
#=GS H3ZKP7_THELI/1-86  AC H3ZKP7.1
G2M2A0_9EURY/1-85             MLAVERFRVNGRDVWIGVIFHGR.IQGISFAFTRGELLE-RIRNLAGFLRRR.NVAVSLDVQPSTYTELVYRVMVGELDNEKALS..ELS.
OGT_PYRFU/2-90                ILEVRKFQVKNKAVYIGTLSEDK.IFGIIFSIDEPEVIRHRIPTLINFLEKRlNKKLEIKEGNSGFSDVVFKTLIGKISNEEAAEfiEVS.
OGT_THEGJ/1-85                MLAVERFGVNGRDIWIGVIFHGR.IQGISFAFTRGELLE-RIRNLAEFLRGR.DVRVSLDVQPSNYTELVYRVLIGELENEKALP..ELS.
F8AIH4_PYRYC/1-86             MISIEAFSLANRKILIAVLWEEK.IEGITFSLDGKEFLKERITRLREFLLRR.GASISLRLETSNYPELVFKILVGEVENREALK..ELS.
OGT_PYRHO/1-86                MLTYKTFKILGREILIGVVWEEK.IQGIAYSLDGLEFLKDQLSRVTSHLKSR.GVKVNLLEEKSRYPDLVFDVLKGKIGNEKGFE..ELS.
B6YXZ4_THEON/1-86             MLSVERFDIARKEVWIAVIFDEK.IQGITFSLDGEGFLRERIANMAFFLKKR.GVNVELTLLESDYPRLVRDVILGKLENEELLP..EL-g
OGT_THESM/1-86                MISIKSFQIGEKEIVIAILFDKK.IQGITFSFDGEQFLQERVNALVEHLTNR.GVKVNLEERDSELPALVYKILIGEIRNQDGLE..YLS.
OGT_THEBM/1-86                MISIEKFEIFGREIWIAVFFEEK.IDGVTFSLDGCEYLMERINSLKALLERR.NVSVNLAEEKSDYPKIVYNVLVGDIENQDALR..FLS.
OGT_PYRSN/1-87                MISYGRFNILGRELTIAIVWNNKgIQGITYSLDGIEFLEEQISRIINHLKSR.NVRVNLSQEESEYPELVFMVLTGYVSNEEAFK..ELS.
G0HLY8_THES4/1-85             MLSVEKFRIANRDVWIAVLFEGG.VQGITFALDGEQFER-NLDRLTGFLRKR.GVDVSIERERSDYPALVRDVIIGRVSNSEILP..ELS.
OGT_PYRAB/1-86                MLSCESFKIKGREIIICVIWEEG.IQGIVYSLDGREFLEKQLSRLISMLNKR.GVSLSLKERHSKYPELVFNVLTGKISNEEGFE..ELS.
OGT_PYRKO/1-85                MLSVEKFRVGERVVWIGVIFSGR.VQGIAFAFDRGTLMK-RIHDLAEHLGKR.GVSISLDVQPSDYPEKVFKVLIGELDNASFLR..ELS.
#=GR OGT_PYRKO/1-85     SS    -EEEEEEEETTEEEEEEEEESSS.EEEEEEESSHHHHHH-HHHHHHHHHHHT.T------B---SHHHHHHHHHTTSS-GGGGGG..GB-.
H3ZKP7_THELI/1-86             MIAIDSFKIGGREIQIAVIYEEK.IQGIAFSLDGEEFLRERIRGLVKHLQKR.GVNVDLREKESDFPQLVYRVLLGEIKNEEALE..YLS.
#=GC SS_cons                  -EEEEEEEETTEEEEEEEEESSS.EEEEEEESSHHHHHH-HHHHHHHHHHHT.T------B---SHHHHHHHHHTTSS-GGGGGG..GB-.
#=GC seq_cons                 MLSlE+FcIssR-lhIuVla-cK.IQGIoFSLDGtEFLccRIssLspaLc+R.GVsVsLcpccScYP-LVacVLlGclcNE-uLc..ELS.
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