GenomeNet

Database: Pfam
Entry: DUF1938
LinkDB: DUF1938
Original site: DUF1938 
#=GF ID   DUF1938
#=GF AC   PF09153.8
#=GF DE   Domain of unknown function (DUF1938)
#=GF AU   Sammut SJ
#=GF SE   pdb_1mgt
#=GF GA   22.10 22.10;
#=GF TC   28.40 95.60;
#=GF NC   21.00 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   10497033
#=GF RT   Hyperthermostable protein structure maintained by intra and
#=GF RT   inter-helix ion-pairs in archaeal O6-methylguanine-DNA
#=GF RT   methyltransferase. 
#=GF RA   Hashimoto H, Inoue T, Nishioka M, Fujiwara S, Takagi M, Imanaka
#=GF RA   T, Kai Y; 
#=GF RL   J Mol Biol. 1999;292:707-716.
#=GF DR   INTERPRO; IPR015236;
#=GF DR   SCOP; 1mgt; fa;
#=GF CC   Members of this family, which are predominantly found in the
#=GF CC   archaeal protein O6-alkylguanine-DNA alkyltransferase, adopt a
#=GF CC   secondary structure consisting of a three stranded antiparallel
#=GF CC   beta-sheet and three alpha helices. Their exact function has
#=GF CC   not, as yet, been defined, though it has been postulated that
#=GF CC   they confer thermostability to the archaeal protein [1].
#=GF SQ   6
#=GS OGT_THEBM/1-86     AC F0LIT8.1
#=GS OGT_PYRAB/1-86     AC Q9V1N7.1
#=GS H3ZKP7_THELN/1-86  AC H3ZKP7.1
#=GS OGT_THEKO/1-85     AC O74023.1
#=GS OGT_THEKO/1-85     DR PDB; 1MGT A; 1-85;
#=GS OGT_PYRFU/2-90     AC Q8TZV2.1
#=GS OGT_THEGJ/1-85     AC C5A3L5.1
OGT_THEBM/1-86                MISIEKFEIFGREIWIAVFFEEKIDGVTFSLDGCEYLMERINSLKALLERRNVSVNLAEEK..SDYPKIVYNVLVGDIENQDALR..FLS..
OGT_PYRAB/1-86                MLSCESFKIKGREIIICVIWEEGIQGIVYSLDGREFLEKQLSRLISMLNKRGVSLSLKERH..SKYPELVFNVLTGKISNEEGFE..ELS..
H3ZKP7_THELN/1-86             MIAIDSFKIGGREIQIAVIYEEKIQGIAFSLDGEEFLRERIRGLVKHLQKRGVNVDLREKE..SDFPQLVYRVLLGEIKNEEALE..YLS..
OGT_THEKO/1-85                MLSVEKFRVGERVVWIGVIFSGRVQGIAFAFDRGTLMK-RIHDLAEHLGKRGVSISLDVQP..SDYPEKVFKVLIGELDNASFLR..ELS..
#=GR OGT_THEKO/1-85     SS    -EEEEEEEETTEEEEEEEEESSSEEEEEEESSHHHHHH-HHHHHHHHHHHTT------B--..-SHHHHHHHHHTTSS-GGGGGG..GB-..
OGT_PYRFU/2-90                ILEVRKFQVKNKAVYIGTLSEDKIFGIIFSIDEPEVIRHRIPTLINFLEKR-LNKKLEIKEgnSGFSDVVFKTLIGKISNEEAAEfiE--vs
OGT_THEGJ/1-85                MLAVERFGVNGRDIWIGVIFHGRIQGISFAFTRGELLE-RIRNLAEFLRGRDVRVSLDVQP..SNYTELVYRVLIGELENEKALP..ELS..
#=GC SS_cons                  -EEEEEEEETTEEEEEEEEESSSEEEEEEESSHHHHHH-HHHHHHHHHHHTT------B--..-SHHHHHHHHHTTSS-GGGGGG..GB-..
#=GC seq_cons                 MLulE+FcltGR-IaIuVIaE-+IQGIsFSlDtsEhLccRIpsLhpaLpKRsVslsLc.cc..ScYP-lVa+VLlG-IcNE-ALc..ELS..
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