GenomeNet

Database: Pfam
Entry: DUF2016
LinkDB: DUF2016
Original site: DUF2016 
#=GF ID   DUF2016
#=GF AC   PF09436.8
#=GF DE   Domain of unknown function (DUF2016)
#=GF AU   Mistry J
#=GF SE   Iyer L
#=GF GA   24.10 24.10;
#=GF TC   24.20 24.90;
#=GF NC   22.70 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   16859499
#=GF RT   The prokaryotic antecedents of the ubiquitin-signaling system
#=GF RT   and the early evolution of ubiquitin-like beta-grasp domains. 
#=GF RA   Iyer LM, Burroughs AM, Aravind L; 
#=GF RL   Genome Biol. 2006;7:R60.
#=GF DR   INTERPRO; IPR018560;
#=GF CC   A predicted alpha+beta domain that is usually fused N-terminal
#=GF CC   to the JAB metallopeptidase. This protein in turn is found in
#=GF CC   conserved gene neighborhoods that include genes encoding the
#=GF CC   bacterial homologs of the ubiquitin modification system such as
#=GF CC   the E1, E2 and Ub proteins [1]. The domain is also known as the
#=GF CC   JAB-N domain.
#=GF SQ   26
#=GS Q1L9T1_CUPMC/4-76       AC Q1L9T1.1
#=GS D9SEQ3_GALCS/4-75       AC D9SEQ3.1
#=GS M4NHD0_9GAMM/12-79      AC M4NHD0.1
#=GS W0SFK5_9RHOO/4-75       AC W0SFK5.1
#=GS A4JUM8_BURVG/4-76       AC A4JUM8.1
#=GS A1W6B4_ACISJ/8-79       AC A1W6B4.1
#=GS A0A0F7JUM1_9SPHN/11-84  AC A0A0F7JUM1.1
#=GS K2CW60_9BACT/3-73       AC K2CW60.1
#=GS Q5NXB5_AROAE/4-75       AC Q5NXB5.1
#=GS Q120V3_POLSJ/3-73       AC Q120V3.1
#=GS B2UDC7_RALPJ/4-76       AC B2UDC7.1
#=GS F4G940_ALIDK/7-78       AC F4G940.1
#=GS Q47D11_DECAR/5-75       AC Q47D11.1
#=GS A0A0M2LZR3_9SPHN/11-83  AC A0A0M2LZR3.1
#=GS F4GGG6_ALIDK/8-79       AC F4GGG6.1
#=GS Q21Q53_RHOFT/9-78       AC Q21Q53.1
#=GS N6Y9C8_9RHOO/4-75       AC N6Y9C8.1
#=GS A0R7L0_PELPD/5-76       AC A0R7L0.1
#=GS D5WNV4_BURSC/4-76       AC D5WNV4.1
#=GS Q7WX35_CUPNH/4-76       AC Q7WX35.1
#=GS Q8XYU8_RALSO/53-126     AC Q8XYU8.1
#=GS Q11ZD2_POLSJ/1-71       AC Q11ZD2.1
#=GS A0A0F5PH19_9SPHN/10-84  AC A0A0F5PH19.1
#=GS C5T055_ACIDE/7-78       AC C5T055.1
#=GS F2LSQ3_BURGS/4-76       AC F2LSQ3.1
#=GS A1VVA1_POLNA/3-75       AC A1VVA1.1
Q1L9T1_CUPMC/4-76                  .........................ADMALQQSFPSVMVPRHGA...LPALE..QVGERLLIAANGVFLEIVRPWLRVVRRLG.eFQHQTAIPYGDATEVTEL-r......
D9SEQ3_GALCS/4-75                  .........................RDVALQSVMPTVMVPRYAE...LEELD..TPGNRILMAENGVWLEVCHAWLYARIPVS..LPLRIPVPYGVIYEELRF-g......
M4NHD0_9GAMM/12-79                 .........................LDMAVLAAMPLAAVPLDGR...FVALE..-TGRRLLAARDGFYIEAANASLYVRWRIA..---ACVTPWGPVTDAIRL-r......
W0SFK5_9RHOO/4-75                  .........................RDIALQHSAPVVTVPRYGG...FTPLV..ENGHRFLVTGDGLWLEARRPWLYLRVPLV..CQKSVPMPYGWVGRELSL-s......
A4JUM8_BURVG/4-76                  .........................LDTVLQQSFPAVMVPSRET...VVPMT..RSGERLLIASDGVYLEVLRPWVRVVRRIA.qYAVSIAVPYGKVEETTAL-l......
A1W6B4_ACISJ/8-79                  .........................RDQALLATCPVIAAPRFGT...LPDMG..-NGQRIIVARNGWFVQTRLDWLDSIVALG.qGLPPMRLPYGEVAEHLRF-s......
A0A0F7JUM1_9SPHN/11-84             aailaaapcypvppigrspaidavr-------------------...---AS..RTGHCLAVGRDGVMLIVRRPWLELDIPVT..PAFPAYLPYGSVGER----rae....
K2CW60_9BACT/3-73                  .......................mn--TTIEGMFPTVIMPREGT...IAPPT..NSGTRYVVARDGLWREVTLPWVTVMHKIA..-HSDFVLPYGVATEQVVV-k......
Q5NXB5_AROAE/4-75                  .........................RDMALQALTPTVMVPRFGC...FEPLS..QPGHRFLVGQNGEWLEVRRAWMYARVQLT..QPSPVVKPYGVVTACLEW-l......
Q120V3_POLSJ/3-73                  .........................LDSIIQGMFPTVIMPREGT...IAPAT..KNGTRYVVAGDGLWREVVLPWVTVMHKIA..-NSDFMLPYGAAEEAVVI-k......
B2UDC7_RALPJ/4-76                  .........................MDMTLQASFPTIMVPKFGS...LTPLS..GSGERLLVGTNGVFLEVVRPWLRVVRKIA.sYEVETAVPYGTVNEETEL-p......
F4G940_ALIDK/7-78                  .........................RDQALLAACPVIAAPRFGA...LPDMG..-NGQRIIVARNGWFVQTRLDWLDSIVALG.hGSPSMRLPYGEVAEHLCF-s......
Q47D11_DECAR/5-75                  .........................RDLALQAVCPVIAAPRFGP...LPDMA..-NGQRIILAANGVFVQVKLDWLDCIQRLS..PALPITLPYGGIEERLAF-t......
A0A0M2LZR3_9SPHN/11-83             aallaavpcfpappsgsspgldavr-------------------...---AS..RAGHCLAIGRDGVFLIVRRPWLELDVPVT..PPIAAYLPYGSVGE-----pra....
F4GGG6_ALIDK/8-79                  .........................RDQALLAACPVVAAPRFGA...LPDMA..-NGQRIVVARNGWFVQTRLDWLDSITALG.lEPPAMRLPYGEVEERLRF-s......
Q21Q53_RHOFT/9-78                  .........................IDRFLATDCPVITMPHDSE..vFEPLK..TPGHRLIVAAGGLYKEIRRAWLHAIVHVA..---RAQTPFGELQTTLSM-p......
N6Y9C8_9RHOO/4-75                  .........................RDAILQQVTPTVMVPLYGA...FEPLG..KLGHRFLSAGNGEWLEVRRSWLYARTRNL..SPGAVAKPYGQVTGTIEW-l......
A0R7L0_PELPD/5-76                  .........................MDAILQEQFPTVMVPRYGD...FVPLA..HNGRRFLSASDGLWLEEKNQWLHILWPLA..LQNQVAMPYGSLQKKVDF-l......
D5WNV4_BURSC/4-76                  ........................p-DLMLQRSFPTVMVPRNET...VAEML..TAGERLLVAENGVFLEVRRPWLSLVRQVA.eFNVRTAIPYGRVTPSTRL-l......
Q7WX35_CUPNH/4-76                  .........................ADAALQQSFPSVMVPRFGA...LAPME..RSGERLLIAANGVFLEIVRPWLSVVRHLG.aFQHRTAIPYGEAAETTDL-r......
Q8XYU8_RALSO/53-126                .........................LDAKLWDSAPTVAVPKFAE...FKQLE..DVGHRFLATAEGLFVEVRRPWLHVIQPVAplNGQTVRPPYGTVKQKVDL-a......
Q11ZD2_POLSJ/1-71                  .........................MDAIIQSQFPTVLAPRFEA...LSPLE..TTGDRFILTRHQVLMEVSRPWLHAIQAIS..APFARQTPYG-A-------gprlgik
A0A0F5PH19_9SPHN/10-84             ......................aaa----LIAAAPCYPVPSTGRspaLDALRdgRAGHGLAVGKDGVMLILRRPWLALDAPLS..PPFAAHIPYGSIGE-----pkad...
C5T055_ACIDE/7-78                  .........................RDQALLAACPVIAAPRFGA...LPDMG..-NGQRVIVARNGWFVQTRLDWLDCIVALG.hGQPLMHLPYGEVAEHLRF-s......
F2LSQ3_BURGS/4-76                  .........................IDTVLQMSFPTVMVPRREP...VHSME..RPGERLLIAANGVFLEVLRPWVRVVRRIA.mYHEKTPIPYGAVDEVTEL-r......
A1VVA1_POLNA/3-75                  .........................LDQITMGVFPLLAASQTGV...LQDPE..KHGVRYVAASDGMWRAIDTAWLKALTPVA.lSSKKAVIPYGRLTQSVEF-l......
#=GC seq_cons                      .........................hDhhLtsshPslhsPRhGs...lsshs..psGcRlllApsGlalElc+sWLcslhtlu...t.sstlPYGplsEplph.t......
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