GenomeNet

Database: Pfam
Entry: DUF2016
LinkDB: DUF2016
Original site: DUF2016 
#=GF ID   DUF2016
#=GF AC   PF09436.9
#=GF DE   Domain of unknown function (DUF2016)
#=GF AU   Mistry J
#=GF SE   Iyer L
#=GF GA   24.10 24.10;
#=GF TC   24.20 24.90;
#=GF NC   23.40 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   16859499
#=GF RT   The prokaryotic antecedents of the ubiquitin-signaling system
#=GF RT   and the early evolution of ubiquitin-like beta-grasp domains. 
#=GF RA   Iyer LM, Burroughs AM, Aravind L; 
#=GF RL   Genome Biol. 2006;7:R60.
#=GF DR   INTERPRO; IPR018560;
#=GF CC   A predicted alpha+beta domain that is usually fused N-terminal
#=GF CC   to the JAB metallopeptidase. This protein in turn is found in
#=GF CC   conserved gene neighborhoods that include genes encoding the
#=GF CC   bacterial homologs of the ubiquitin modification system such as
#=GF CC   the E1, E2 and Ub proteins [1]. The domain is also known as the
#=GF CC   JAB-N domain.
#=GF SQ   36
#=GS A0A085FMC9_9BURK/4-74    AC A0A085FMC9.1
#=GS W0SFK5_9RHOO/4-75        AC W0SFK5.1
#=GS A1W6B4_ACISJ/8-79        AC A1W6B4.1
#=GS A0A0F7JUM1_9SPHN/11-84   AC A0A0F7JUM1.1
#=GS Q120V3_POLSJ/3-73        AC Q120V3.1
#=GS F4G940_ALIDK/7-78        AC F4G940.1
#=GS G6EJV6_9SPHN/10-84       AC G6EJV6.1
#=GS A0A0M2LZR3_9SPHN/11-83   AC A0A0M2LZR3.1
#=GS A0A069PJ89_9BURK/4-76    AC A0A069PJ89.1
#=GS Q21Q53_RHOFT/9-78        AC Q21Q53.1
#=GS A0A177P492_9GAMM/11-82   AC A0A177P492.1
#=GS A0R7L0_PELPD/5-76        AC A0R7L0.1
#=GS A0A0K9K0K3_9BURK/9-81    AC A0A0K9K0K3.1
#=GS Q7WX35_CUPNH/4-76        AC Q7WX35.1
#=GS Q11ZD2_POLSJ/1-71        AC Q11ZD2.1
#=GS A0A0F5PH19_9SPHN/10-84   AC A0A0F5PH19.1
#=GS A0A0Q6W4E1_9BURK/5-76    AC A0A0Q6W4E1.1
#=GS C5T055_ACIDE/7-78        AC C5T055.1
#=GS A0A139BN16_9PROT/4-75    AC A0A139BN16.1
#=GS A1VVA1_POLNA/3-75        AC A1VVA1.1
#=GS D9SEQ3_GALCS/4-75        AC D9SEQ3.1
#=GS Q1L9T1_CUPMC/4-76        AC Q1L9T1.1
#=GS M4NHD0_9GAMM/12-79       AC M4NHD0.1
#=GS Q5NXB5_AROAE/4-75        AC Q5NXB5.1
#=GS B2UDC7_RALPJ/4-76        AC B2UDC7.1
#=GS Q47D11_DECAR/5-75        AC Q47D11.1
#=GS F4GGG6_ALIDK/8-79        AC F4GGG6.1
#=GS A0A172UG16_9GAMM/11-82   AC A0A172UG16.1
#=GS N6Y9C8_9RHOO/4-75        AC N6Y9C8.1
#=GS A0A085ERT2_9BURK/54-125  AC A0A085ERT2.1
#=GS Q8XYU8_RALSO/53-126      AC Q8XYU8.1
#=GS W7WVK0_9BURK/6-77        AC W7WVK0.1
#=GS A0A0Q4XRM1_9BURK/5-75    AC A0A0Q4XRM1.1
#=GS A0A0L1KJN0_9BURK/10-82   AC A0A0L1KJN0.1
#=GS A0A0L0M4C1_9BURK/9-81    AC A0A0L0M4C1.1
#=GS F2LSQ3_BURGS/4-76        AC F2LSQ3.1
A0A085FMC9_9BURK/4-74               .........................RDVVLQRVCPIVAMPKFSP...LEPLA..QNGERIVMAANGTFLEVRRSWARFVRKVG..-EVNTVVPFGTLEEST---tyf....
W0SFK5_9RHOO/4-75                   .........................RDIALQHSAPVVTVPRYGG...FTPLV..ENGHRFLVTGDGLWLEARRPWLYLRVPLV..CQKSVPMPYGWVGRELSL-s......
A1W6B4_ACISJ/8-79                   .........................RDQALLATCPVIAAPRFGT...LPDMG..-NGQRIIVARNGWFVQTRLDWLDSIVALG.qGLPPMRLPYGEVAEHLRF-s......
A0A0F7JUM1_9SPHN/11-84              aailaaapcypvppigrspaidavr-------------------...---AS..RTGHCLAVGRDGVMLIVRRPWLELDIPVT..PAFPAYLPYGSVGER----rae....
Q120V3_POLSJ/3-73                   .........................LDSIIQGMFPTVIMPREGT...IAPAT..KNGTRYVVAGDGLWREVVLPWVTVMHKIA..-NSDFMLPYGAAEEAVVI-k......
F4G940_ALIDK/7-78                   .........................RDQALLAACPVIAAPRFGA...LPDMG..-NGQRIIVARNGWFVQTRLDWLDSIVALG.hGSPSMRLPYGEVAEHLCF-s......
G6EJV6_9SPHN/10-84                  ......................aaa----LIAAAPCYPVPSTGRspaLDALRdgRAGHGLAVGKDGVMLILRRPWLALDAPLS..PPFAAHIPYGSIGE-----pkad...
A0A0M2LZR3_9SPHN/11-83              aallaavpcfpappsgsspgldavr-------------------...---AS..RAGHCLAIGRDGVFLIVRRPWLELDVPVT..PPIAAYLPYGSVGE-----pra....
A0A069PJ89_9BURK/4-76               ........................g-DMALQRSFPTVMMPRREP...VAPML..AAGERLLIGENGVFIEIDLPWLSVVRRIA.aYTVPTAIPYGKVVESTVL-r......
Q21Q53_RHOFT/9-78                   .........................IDRFLATDCPVITMPHDSE..vFEPLK..TPGHRLIVAAGGLYKEIRRAWLHAIVHVA..---RAQTPFGELQTTLSM-p......
A0A177P492_9GAMM/11-82              .........................RDRILFGETPTYMQPLFGE..kLPAPE..LGKHRFVIGQEGVVLEAINEVFEVRLPVA..-QSIIKLPYGVLG------aqgvrl.
A0R7L0_PELPD/5-76                   .........................MDAILQEQFPTVMVPRYGD...FVPLA..HNGRRFLSASDGLWLEEKNQWLHILWPLA..LQNQVAMPYGSLQKKVDF-l......
A0A0K9K0K3_9BURK/9-81               ........................g-DAALQRSFPSVMVPRREP...VTPMQ..TCDERLLIGENGVFIEIDLPWLSVVRRIA.hHTVPTAIPYGKVIESTVL-r......
Q7WX35_CUPNH/4-76                   .........................ADAALQQSFPSVMVPRFGA...LAPME..RSGERLLIAANGVFLEIVRPWLSVVRHLG.aFQHRTAIPYGEAAETTDL-r......
Q11ZD2_POLSJ/1-71                   .........................MDAIIQSQFPTVLAPRFEA...LSPLE..TTGDRFILTRHQVLMEVSRPWLHAIQAIS..APFARQTPYG-A-------gprlgik
A0A0F5PH19_9SPHN/10-84              ......................aaa----LIAAAPCYPVPSTGRspaLDALRdgRAGHGLAVGKDGVMLILRRPWLALDAPLS..PPFAAHIPYGSIGE-----pkad...
A0A0Q6W4E1_9BURK/5-76               .........................RDAALQAACPVIAAPRHGD...LPPMV..-PGLRIVAAANGLFVQVRLPWLDCLQRCG.sVDLGLPLPYGTLAPWLRL-s......
C5T055_ACIDE/7-78                   .........................RDQALLAACPVIAAPRFGA...LPDMG..-NGQRVIVARNGWFVQTRLDWLDCIVALG.hGQPLMHLPYGEVAEHLRF-s......
A0A139BN16_9PROT/4-75               .........................RDVALQSVMSTVMVPHFSE...LVELD..TPGNRILMASNGIWLEVCRAWFYARVPIA..KPLSMATPYGMVSEVLRF-g......
A1VVA1_POLNA/3-75                   .........................LDQITMGVFPLLAASQTGV...LQDPE..KHGVRYVAASDGMWRAIDTAWLKALTPVA.lSSKKAVIPYGRLTQSVEF-l......
D9SEQ3_GALCS/4-75                   .........................RDVALQSVMPTVMVPRYAE...LEELD..TPGNRILMAENGVWLEVCHAWLYARIPVS..LPLRIPVPYGVIYEELRF-g......
Q1L9T1_CUPMC/4-76                   .........................ADMALQQSFPSVMVPRHGA...LPALE..QVGERLLIAANGVFLEIVRPWLRVVRRLG.eFQHQTAIPYGDATEVTEL-r......
M4NHD0_9GAMM/12-79                  .........................LDMAVLAAMPLAAVPLDGR...FVALE..-TGRRLLAARDGFYIEAANASLYVRWRIA..---ACVTPWGPVTDAIRL-r......
Q5NXB5_AROAE/4-75                   .........................RDMALQALTPTVMVPRFGC...FEPLS..QPGHRFLVGQNGEWLEVRRAWMYARVQLT..QPSPVVKPYGVVTACLEW-l......
B2UDC7_RALPJ/4-76                   .........................MDMTLQASFPTIMVPKFGS...LTPLS..GSGERLLVGTNGVFLEVVRPWLRVVRKIA.sYEVETAVPYGTVNEETEL-p......
Q47D11_DECAR/5-75                   .........................RDLALQAVCPVIAAPRFGP...LPDMA..-NGQRIILAANGVFVQVKLDWLDCIQRLS..PALPITLPYGGIEERLAF-t......
F4GGG6_ALIDK/8-79                   .........................RDQALLAACPVVAAPRFGA...LPDMA..-NGQRIVVARNGWFVQTRLDWLDSITALG.lEPPAMRLPYGEVEERLRF-s......
A0A172UG16_9GAMM/11-82              .........................RDRILFGETPTYMQPLFGE..kLPAPE..LGKHRFVIGQEGVVLEAINEVFEVRLPVA..-QSIIKLPYGVLG------aqgvrl.
N6Y9C8_9RHOO/4-75                   .........................RDAILQQVTPTVMVPLYGA...FEPLG..KLGHRFLSAGNGEWLEVRRSWLYARTRNL..SPGAVAKPYGQVTGTIEW-l......
A0A085ERT2_9BURK/54-125             .........................MDMALLAAAPVAAVPRYAP...FHALQ..ENGHRFLLAADGLHLEVRRPWLHYIQQLA..KHTAVAIPFGEMAKKCEL-d......
Q8XYU8_RALSO/53-126                 .........................LDAKLWDSAPTVAVPKFAE...FKQLE..DVGHRFLATAEGLFVEVRRPWLHVIQPVAplNGQTVRPPYGTVKQKVDL-a......
W7WVK0_9BURK/6-77                   .........................MDGVLLDMFPVVAVPPSGQ...LAKPS..RDGQRYLVGNSGLFREVSTPWLYAVYPIA..SISGLATPFGEVKTTVTI-g......
A0A0Q4XRM1_9BURK/5-75               .........................RDLALQASCPVLAAPRFGP...LPDMV..-NGQRVIVAANGVFVQVRLDWLDCVQRLA..PPLGVPLPFGALQERLQF-s......
A0A0L1KJN0_9BURK/10-82              ........................g-DAALQRSFPTVMVPRHEP...VAPIV..AAGERLLIGENGMFIEIDLPWLSVVRRIA.hYTVPTAVPYGHVVEATVL-r......
A0A0L0M4C1_9BURK/9-81               ........................g-DAALQRSFPSVMVPRREP...VAPML..AAGERLLIGENGVFIEINLPWLSVVRRIA.hYTVPTAIPYGRVVESTVL-r......
F2LSQ3_BURGS/4-76                   .........................IDTVLQMSFPTVMVPRREP...VHSME..RPGERLLIAANGVFLEVLRPWVRVVRRIA.mYHEKTPIPYGAVDEVTEL-r......
#=GC seq_cons                       .........................hDhsL.sshPslhsP+aGs...lsshp..psGcRlllupsGlalElcpsWLpslhtlu...thssslPYGplsEphph.s......
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