GenomeNet

Database: Pfam
Entry: DUF2115
LinkDB: DUF2115
Original site: DUF2115 
#=GF ID   DUF2115
#=GF AC   PF09888.5
#=GF DE   Uncharacterized protein conserved in archaea (DUF2115)
#=GF AU   COGs, Finn RD, Sammut SJ
#=GF SE   COGs (COG4066)
#=GF GA   25.00 25.00;
#=GF TC   25.40 25.30;
#=GF NC   24.40 23.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019215;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   95
#=GS D3S4H4_METSF/2-160   AC D3S4H4.1
#=GS Y665_METMP/2-159     AC P60818.1
#=GS A9A8A2_METM6/2-162   AC A9A8A2.1
#=GS Q0W0W4_UNCMA/17-189  AC Q0W0W4.1
#=GS J1L5A7_9EURY/21-191  AC J1L5A7.1
#=GS F6D7G5_METSW/15-175  AC F6D7G5.1
#=GS I7L107_METBM/79-241  AC I7L107.1
#=GS Y646_METJA/2-160     AC Q58062.1
#=GS B9AGQ7_METSM/1-54    AC B9AGQ7.1
#=GS F0T6P2_METSL/4-128   AC F0T6P2.1
#=GS D9PX49_METTM/4-150   AC D9PX49.1
#=GS Y812_METTH/2-160     AC O26903.2
#=GS R7PXX0_9EURY/20-180  AC R7PXX0.1
#=GS Q12YF8_METBU/10-167  AC Q12YF8.1
#=GS Q2FNU7_METHJ/30-191  AC Q2FNU7.1
#=GS C9RFP6_METVM/2-160   AC C9RFP6.1
#=GS I7KZ45_METBM/22-182  AC I7KZ45.1
#=GS F6BAZ9_METIK/2-160   AC F6BAZ9.1
#=GS G0H402_METMI/2-159   AC G0H402.1
#=GS H8I8R3_METCZ/19-180  AC H8I8R3.1
#=GS A2SQ90_METLZ/26-184  AC A2SQ90.1
#=GS F6D7G4_METSW/24-182  AC F6D7G4.1
#=GS D5EBF8_METMS/8-166   AC D5EBF8.1
#=GS E1RKK7_METP4/2-154   AC E1RKK7.1
#=GS E3GYV3_METFV/11-169  AC E3GYV3.1
#=GS T2GHV1_METTF/12-170  AC T2GHV1.1
#=GS R9SIV5_9EURY/3-149   AC R9SIV5.1
#=GS H1KZ94_9EURY/2-160   AC H1KZ94.1
#=GS C8VWC1_DESAS/2-158   AC C8VWC1.1
#=GS D2ZMF6_METSM/20-180  AC D2ZMF6.1
#=GS A3CUT9_METMJ/6-168   AC A3CUT9.1
#=GS E1RF46_METP4/21-182  AC E1RF46.1
#=GS U6EA65_9EURY/15-173  AC U6EA65.1
#=GS D1YZJ5_METPS/35-197  AC D1YZJ5.1
#=GS Q2NHX8_METST/2-152   AC Q2NHX8.1
#=GS R9SKF2_9EURY/15-175  AC R9SKF2.1
#=GS Y221_METM6/2-159     AC A9A7B8.1
#=GS Y1691_METM7/2-159    AC A6VJX1.1
#=GS Q2FL19_METHJ/21-192  AC Q2FL19.1
#=GS K4LFF1_9FIRM/18-173  AC K4LFF1.1
#=GS A7I898_METB6/33-193  AC A7I898.1
#=GS W9DUA1_METTI/18-177  AC W9DUA1.1
#=GS F0TAZ0_METSL/15-175  AC F0TAZ0.1
#=GS F6D7G3_METSW/41-199  AC F6D7G3.1
#=GS Y666_METKA/2-137     AC Q8TXK6.1
#=GS E1RH52_METP4/29-200  AC E1RH52.1
#=GS K4MED9_9EURY/2-160   AC K4MED9.1
#=GS K2RQ20_METFO/13-172  AC K2RQ20.1
#=GS R7PVU2_9EURY/3-149   AC R7PVU2.1
#=GS D7E9K9_METEZ/2-160   AC D7E9K9.1
#=GS A4FZ14_METM5/5-165   AC A4FZ14.1
#=GS F8ANK7_METOI/2-159   AC F8ANK7.1
#=GS U6EC76_9EURY/13-172  AC U6EC76.1
#=GS A3CXE2_METMJ/58-229  AC A3CXE2.1
#=GS K6U1R5_9EURY/15-175  AC K6U1R5.1
#=GS A5UJ91_METS3/3-149   AC A5UJ91.1
#=GS A6UW08_META3/2-163   AC A6UW08.1
#=GS K2RTT9_METFO/15-174  AC K2RTT9.1
#=GS R9SM74_9EURY/15-177  AC R9SM74.1
#=GS B9AD87_METSM/3-149   AC B9AD87.1
#=GS K2QA68_METFO/15-173  AC K2QA68.1
#=GS B8GKS1_METPE/34-196  AC B8GKS1.1
#=GS K2QDS7_METFO/16-175  AC K2QDS7.1
#=GS K6U060_9EURY/16-176  AC K6U060.1
#=GS B9AH65_METSM/20-180  AC B9AH65.1
#=GS D9PX50_METTM/12-170  AC D9PX50.1
#=GS D3E3I4_METRM/20-177  AC D3E3I4.1
#=GS Y909_METM5/2-159     AC A4FYD1.1
#=GS T2GHJ4_METTF/3-152   AC T2GHJ4.1
#=GS E1RKK9_METP4/41-212  AC E1RKK9.1
#=GS L0HI22_METFS/76-238  AC L0HI22.1
#=GS B8GKT1_METPE/36-208  AC B8GKT1.1
#=GS F0TAZ1_METSL/15-173  AC F0TAZ1.1
#=GS A6USE8_METVS/2-159   AC A6USE8.1
#=GS D7DU54_METV3/2-156   AC D7DU54.1
#=GS B8GII9_METPE/31-202  AC B8GII9.1
#=GS H1YYU4_9EURY/19-191  AC H1YYU4.1
#=GS D3E0U5_METRM/2-158   AC D3E0U5.1
#=GS K6U173_9EURY/15-174  AC K6U173.1
#=GS B8GG14_METPE/6-153   AC B8GG14.1
#=GS K6T3P0_9EURY/15-173  AC K6T3P0.1
#=GS Y811_METTH/3-152     AC O26902.1
#=GS D5VU42_METIM/2-152   AC D5VU42.1
#=GS L0HGV6_METFS/29-200  AC L0HGV6.1
#=GS A5UK44_METS3/20-180  AC A5UK44.1
#=GS N6VQJ6_9EURY/2-158   AC N6VQJ6.1
#=GS J0S9P9_9EURY/35-197  AC J0S9P9.1
#=GS A7IAC9_METB6/28-199  AC A7IAC9.1
#=GS C7P6B7_METFA/2-160   AC C7P6B7.1
#=GS A2STY9_METLZ/48-217  AC A2STY9.1
#=GS H1Z2H4_9EURY/18-178  AC H1Z2H4.1
#=GS A3CTH3_METMJ/19-180  AC A3CTH3.1
#=GS D2ZMX5_METSM/1-54    AC D2ZMX5.1
#=GS K4KSS2_9FIRM/1-74    AC K4KSS2.1
#=GS D2ZRF0_METSM/3-149   AC D2ZRF0.1
D3S4H4_METSF/2-160              .....................k-AKELFEKLKKELDNFSIYDIMMIRSFIERDAKFLP..EKYKNHYIEAMMKYLIETFNEIKK.---KRVEEIKDEEIDEKKLNEMLNRIERFRKYYTPD-........EERFINLSKILCPYLAFIAKKPLHPEYLTFPGNVRIIKK....GNSYYCPVKNK..QLN-EYSLCEFCVAKS-i.
Y665_METMP/2-159                .....................k-SRKFFSKLKEESYDVSIFDLMNAKVYLEKDMTYLP..QDYKKGYIEDFFTFFPEVLKEIKN.-KTEEEIEDF--EIEDEEIKRVELRLCSMGSKQTG--........RESYEKLVKTVINYLIFINERPLHALTTRFPGGKQIIEK....NGNYYCPIKNA..QSN-ELSICEFCICKD-l.
A9A8A2_METM6/2-162              .....................n-AKELFKNLKENARNYQVYDLMKVKYYFDQAVEVVL..EKYRENFVYSYFGLYYETFLEIKN.KSESEILDFEVTEVEIQNLNSRLDSIYLGLEEEKR--........NKEVLNLQKIVYPYLIFISKKPLHHITLRFPGGKTLIEK....NGTYFCPARNS..QEN-DLGVCEFCCCKD-y.
Q0W0W4_UNCMA/17-189             .....................l-KRELAQELADEINRFSVYDLQYVSARLEKDISDLP..SPYREKIRPYFMEQYFGRYNRIMTmRGSGELEKIEGEIKDPELFRDFCRMITARYPDRELQDepeeytqgSPFNSLFYYLISIFYMFVLDEPGHPAGMPFPGGFTVREH....DGVVYCPIRDK..EKDVEYSICNFCPAKQD..
J1L5A7_9EURY/21-191             ......................TRGELGRAIAEEAGRFSLYDLQRIGGGIRREVEALP..EPYRSRVRPYFEEQIFGAYHRLMCsHRSGAFARMDDPIPDPEHFSAFVALIPRGCLDRKGSQtdi..gfsKPLHTLFYYLVTGYTIFVEGGPGHPVGTPFPGGFAVERR....GNEYYCPIRDK..EEDVPFSICNVCPARQM..
F6D7G5_METSW/15-175             ......................KKTDLLVVLKEEVSNIHITDIMRASAFLKEDAKYVQ..ASYREGYRKAYVEGFILRITDLKN.----DKSQH-GGYVDLEEFKKALNLLGDQRAQLEIEGn......fDPCFSKLYVTMSLYTSFILEEPIHVVGTPFPGGFEVKFQ....DGEYLCPVKDK..QKDNPGAVCGFCIAKQE..
I7L107_METBM/79-241             ......................TKGELLHIIAGEVGAFDLHDLEAMNAGFERKVASLP..EDYRDRLLASVREEIFGAHHRLVLlSRNGAAPSMDSP--PAPAHAAYWAMVAEACTEKAREK........DPRYLYLKYLLSGFAMFVLAEPAHPVGTPFPGGQIVDEW....EGAYLCPVRDM..ADDVPFALCPYCPAAQS..
Y646_METJA/2-160                .....................k-ARELFEKLKKELNNFSIYDIMMIRSFIEKDAKYLP..PQYKNHYVEAMMKYLIETFNEIRK.-KSVDEIQD--EEIDEEKLNEMLNRIERFRKYYTPD-........EERFINLSKILCPYLAFIAKKPLHPEYLTFPGNVKIIKK....GNNYYCPVKNK..QLN-EYSLCEFCVCKS-i.
B9AGQ7_METSM/1-54               ....................mh------------------------------------..------------------------.------------------LKKYIFNLNETLDPHKS--........SAEFCIIVFLSILYANYILEEPVHPEGLNFQNHK-----....-----------..-----------------k.
F0T6P2_METSL/4-128              ...............pktdidd------------------------------------..-----ELQGAMSSYNAENFRRLTE.---THFSGE-DEEINTKELTALEESIDHYFELYAPD-........NIEFREFIKIVSVYLTFIEKRPLHPPGIIFSGGDTVYEN....KGIYYCTGKKQ..FKNDDHSLCNFCVCHE-i.
D9PX49_METTM/4-150              ...................dpa---SLKTILRECAASISIFDIIRIREFIERECAHVP..RGYREAYIKTYTGIAVEAVLALKG.----GVGDI---TADRK---SLLRTLKRLYDTSS---........----PLIVVLTVIYRNFILSEPLHPVGTPFPGSYSVTEE....HGTYYCPVKDK..QKDNPSALCDICIAEQT..
Y812_METTH/2-160                .....................t-EMQLLEMLKKEASSVHIKDIMSASVYLREDARYLP..PREQKEFIERFTRAFFNRIRDIKN.----DKNIYQ-GHVDTAGLKEFIDFLDQQLSQAKTEN........ERCFQKIARIITIYVTFVRKEPVHPVGTRFPGGFTVRRE....GNVFYCPVKDR..QINTPGALCRFCVSIQD..
R7PXX0_9EURY/20-180             ......................TKTELLKLLKKYCKIISPYDLMLATARMREEGKYVQ..ANYREKYLEVYVKYFIMRVKEILD.-----NNNYLDEAIDKESFDESFNLLKYQFEKERNYSi......eEDKFPLIYIITALYTTFILEEPIHPVGTEFPGSLKVEEK....NGEFYCPVKDK..QKDNENAICNLCLAEQT..
Q12YF8_METBU/10-167             .....................d-TKELLASLEKDARRISNNDIMKARSFMLNYVKFLP..EKYKKAYSTELFSYYYETFMEIKG.LRSNPVIE----EIDIETYNELVKNYSQQFNEDPL--........ESYFQRFMSVVTPYLIFITKKPLHPVGMILPGGMTIMEP....NGEYYCPIKNK..QTEVDIALCKYCICKD-n.
Q2FNU7_METHJ/30-191             .....................m-RGDLGLAIADIVLTYSPNDLKQMKVNFSGKIDSLS..PDYKKELEETIAVFLDGTYQNIRLmNQQGSFATIQEPVSDQA--KEYWMMVADRCSTGDIP-........GNRLRFLKFLLSGFCMFVQEIPGHPVGMPFPGGDKVDFI....DGKYYCPVRTK..SHDVDAALCPFCPAEQT..
C9RFP6_METVM/2-160              .....................k-SRELLKKLKKELENFSIYDIMMVRSFIEKDAKYLP..PQYREHYINSMMKYLIETFHEIKK.---KKCEDIKDEEIDEEKLKKMLERIERFKKYNTPE-........EEKFIKLSKILCPYLAFIAKKPLHPTYLTFPGNVRIIKK....GNTYYCPVKNK..QIN-EYSLCEFCVCR--sf
I7KZ45_METBM/22-182             .....................t-RAELAEVLYREVSGYSLFDLQALRGRVERDLRSLP..AGYRQRLYPRVMEQLFDTHHALIStARRGDLDALDEP--LTGQFQEFCGMVEKTCLTLES--........DPRLSLLYYLLAAFNLFVLDRPGHPVGTPFPGGFEVEVR....NGEYVCPVREK..ADDVENALCPYCPAKQS..
F6BAZ9_METIK/2-160              .....................n-SRELFKKLKKEAKEFSIYDMMKARCFMENDAKYLP..PQYRNEFLESLGMYFYNVLNEIKN.-RDKNSVES--FEIDEEKLEKLIERIESFKKMNSEN-........EDAFIRLSKIIAPYLIFIAKKPIHPENLVFPGKKKIIKK....GNTYYCPVKNK..QKN-EYSLCEFCVCKD-i.
G0H402_METMI/2-159              .....................k-SRKFFSKLKEESYDVSIFDLMNAKVYLEKDMTYLP..QDYKKGYIEDFFTFFPEVLKEIKN.-KTEEEIEDF-E-IEDEEIIKADLRLCSMGSKQTG--........RESYEKLVKTVINYLIFINERPLHALTTRFPGGKHIIEK....NGNYYCPIKNA..QSN-ELSICEFCICKD-l.
H8I8R3_METCZ/19-180             .....................r-KSELGEALAIELGRLSVFDLQRISAFVEAEANKVP..SPYREKVRPYFTEQLFGSYFRLMRmHGDGTLKAMDGRIKDEKAFEEYCLMAMEESENRDRG-........--QYGWYYYLVSCFTMFVLEEPGHPVGMPFPGGFIVERR....GDNYYCPIREK..EKDVPFALCNFCPAMQ-s.
A2SQ90_METLZ/26-184             .....................r-KGALLALLKEKGQLYSPEDLELMLNRYAKKLENVP..KEYGDSLMQYARIQIVDGYHRMMT.---DELTPIHAAVLLPPSWKAFTADARRAASKGTP--........GDRLRSLKYLIAAYSVYIKDEPVHPVGMPFPGGFSVEQY....DGEYYCPVRAV..WNDIDDAFCKYCPAIQ-s.
F6D7G4_METSW/24-182             ......................KKEELVEILKNDADDISIRDLMEIYTNMLKEGRYVQ..KSYHEDYIRFYIKSFSKYLKGLKT.----DETPYN-SYVDMEKLRGTVEHLQKMFEESERDS........SPGSKKILYLTSIYSTFVLEEPIHIVGSQFPGGLKVKKN....GETYLCPVKDK..QKESPNALCKFCIAEQE..
D5EBF8_METMS/8-166              ....................ng--QELITNLKNKANRFTPSDFMKIRSRILQSTENLP..SKYRQMYGEELFRHLYETIDEIRK.----YKATPQLPTFDRKDCLELIQRIDLMREEDNEK-........NKLFTDMVKLTSIYLIFVAGKPLHPLNMEFPGGRKIAKK....DNAYYCPVKNK..QKDVEIALCKFCICKDM..
E1RKK7_METP4/2-154              .....................k-ASELFEAIKDDLSTISEY------ISLMKCIHETN..SKDSATQSSILVEYDYAAYREIMN.----EACPNPDIVIESDRVEEFREALNRYFDEYAPG-........ETDLRCYVTNISLYLVFIAKKPLHPPGIDVPDLKVIKGE....DGHYYCSRKGK..IFDGEPTLCRYCVCR--pi
E3GYV3_METFV/11-169             .....................s-KRKLLHILKKASRKVSVNDLMNASVFLNEEIKYMH..KQEKKEYIRRFMHAFFMRLNELKN.----DKKRYE-GSVDIKKLKELVDFMENKIKNSKSEK........ERSFYKIAAIVSIYATFVKEVPIHPLSTKFPGNLKIRYR....KGKYLCPVKDK..QKESPEALCKFCVAVQD..
T2GHV1_METTF/12-170             .....................t-EMQLLEMLKKEASSVHIKDIMSASVYLREDARYLP..PREQKEFIERFTRAFFNRIRDIKN.----DKNIYQ-GHVDTAGLKEFIDFLDQQLSQAKTEN........ERCFQKIARIITIYVTFVRKEPVHPVGTRFPGGFTVRRE....GNVFYCPVKDR..QINTPGALCRFCVSIQD..
R9SIV5_9EURY/3-149              ........tmntkelfdeiyey--------------------------MINYDHARVP..HGYSTDAISLLTRYNYYTYKEIIN.RKHSGSLKV---EVDDNKVNDFKDRVDYYFEENSPG-........DYEYRDFIKYISLYLTFIVRKSLHPVGIKSKD-MTVTKD....NNKFYCTGKKR..FIKDRNSLCKYCVSR--sk
H1KZ94_9EURY/2-160              .....................d-SKELFKKLKKEAREFSIFDMMKARCFMENDAKYLP..PQYRNEFLESLGMYFYNILNEIKN.---KDESSIESYEIDEEKLKRLIGRIESFKKMNSEN-........ENAFIRLSKIIAPYLIFIVKKPIHPENLVFPGKKKIIKK....GNTYYCPVKSK..QKN-EYSLCEFCVCRD-i.
C8VWC1_DESAS/2-158              .....................n-NRKLLDLIKKKAEYFSTEEIIQRSAPGEQEPQHTD..R--LKYVSRLVARYNLETFLEIKS.---RDRIDI-LEDIDSDTLNDFTFRIEKYMDENAPG-........LADLKTYILIVSTYLAFIVKKPLHPPGMLFVGGQKIVEK....DNKFYCPMKNK..QLRTAFSLCKYCASRD-i.
D2ZMF6_METSM/20-180             ......................TKTELLKLLKKYCKIISPYDLMLATARMREEGKYVQ..ANYREKYLEVYVKYFIMRVKEILD.-----NNNYLDEAIDKESFDESFNLLKYQFEKERNYSi......eEDKFPLIYIITALYTTFILEEPIHPVGTEFPGSLKVEEK....NEEFYCPVKDK..QKDNANAICNLCLAEQT..
A3CUT9_METMJ/6-168              ......................TKGDLLRIIADETAAYDLRDLEAMNARFERKVAHLP..EDYRDRLLSSVREEIFGAHHRLVLlSRNSGGRELDG--PPAPALSAYCSMVAEACTAKAREK........DPKYLYLKYLLSAFTIFVVEEPAHPVGTPFPGGQIVDEW....EGTYLCPVRDL..ADDVPFALCPYCPAVQ-s.
E1RF46_METP4/21-182             ......................TRGDLGKAIAEAVSGYSPGDLKKIQWNFSGRIRNIN..PLYRSKLERTVNGHLSETWEKIRImNQQGSFSPMKEPL--PEDAKQFWNIAAAECSSGEPE-........KDRIRFLKYLLAGFCIFVMNVPPHPVGMPFPGGDKVQLI....DGIYYCPVREK..SGDVDSALCPFCPARQT..
U6EA65_9EURY/15-173             .....................s-KDELLKILKKEARSIHITEIMKASNFLREDASYMP..PKERDDYIARFTKAFFTRIKDIKD.----DQSNYK-GMVNPEKLSEFLKVQEELSQKSINND........EKCFHRIACVVSTYTAFVKEESIHPVGTRFPGGFTLKLV....NSVYLCPVKDK..QIDTPSALCRFCVSVQD..
D1YZJ5_METPS/35-197             .....................k-KCELGEALAFELGRLSILDLQAMSAFLEYEINKLP..SPYRESIHPYFTEQLFGSYFKLMRmHGDGSLKKIPGEIEDQKTFLEYCAMITGGEDGHLE--........ESYYGGYYHLVSCFTIFVMDEPGHPVGMPFPGGFRVERR....PEGFYCPIRDK..EKDVLFSICNFCPAKQS..
Q2NHX8_METST/2-152              ....................ky--NTLKEILKEKIREVTLQELYDLSFEFNEDTKYLP..REYKKKYIESVLNVIINRFNSLKN.---------TQENFEGEVTKKEASEINKILTKT----........NNRLTDALNVIVVYATYLKREPIHLPGTEFPGMQSIYTD....GENYYCPIKRY..HIDNDKALCRYCVAKE-t.
R9SKF2_9EURY/15-175             .....................s-KNDILNIIKDEARHLTIYDEMAASSYLQEEGKYIQ..KSYRDEYLDVTIKYFLKRLHRIKN.----DNRDYP-ETVDKKRLKGSLRILKNQYLQQKGNLp......eSNKTPLMYGIISIYTTFILEESIHPLNTPFPAGEKIILK....DGTYYCPVKHN..QSKNPDALCRLCIAKE-m.
Y221_METM6/2-159                .....................k-SRNFFSKLKEESYDVGIFDLMNAKVYLEKDLTYLP..EDYKKGYLEDFFTFFPEVLREIKN.-KTEEEIEDF--EINEEEIKKVDSRICSMGSIGAS--........RDSYEKLVKTVINYLIFINKRPLHALTTRFPGGKQIIEK....NGNYYCPIKNA..QSN-ELSICEFCICKD-l.
Y1691_METM7/2-159               .....................n-SRKLFSKLKEESYDVSIFDLMNAKVYLEKDMTYLP..EDYKKGYLEDFFTFFPEVLREIKN.-KTEEEIEDF--EIDEEEIKKVDLRLCSMGSKKMG--........RNSYEKLVKTVINYLIFINKRPLHALTTRFPGGKQIIEK....NGNYYCPIKNA..QSN-ELSICEFCICKD-l.
Q2FL19_METHJ/21-192             ......................NKGELGTIVAEEIQKYSVFELQVIGGRLHLEIERLP..AHYRHKIRSYFKDQIFGAHHILLSrYRSGYFRKCTDQIRDPELFLSYCRMIPDGCMAWDEGMwkn.peiwSPRHRLFYYLIAAYTMFVEDLPGHPVGMPFPGGQVVEKR....GNEYYCPIRDK..EKDVFFSICNFCPARQT..
K4LFF1_9FIRM/18-173             .....................n-TQDLFIIIKNEAESLHIENFLNLNKSTNQVFEPGS..IEY---ISNLMSNYNLSNYFEIIR.----KENVNNPEDINPHLIEDFSNRIEIYMDENAPG-........QIDLKQYIRIISTYLAFISKKPLHPLGMIMQGTEKIIKQ....NDKYYCPMRRA..QIKGKLSLCIYCVCRD-i.
A7I898_METB6/33-193             ......................TRGDLGKKIAALVLEYSPRDIRQMMTNFGNTIQDIS..MEYRAELEASVTLHLLGTYQDIRLaEQQGSFARMKEQVTAHE--RSYWGMVEGQCRNGPG--........DLRLRFLKFLLAGFAMIVRQEPGHPVGMRFPGGDRVERI....DGVYYCPVREK..ANDVDAALCPFCPAQQT..
W9DUA1_METTI/18-177             .....................n-TTELLLSLQKDSLSINNADISLARAYAMEAVEHVP..EPYKTIYSADYFVFLYESFLEIRK.CRPDEII-IQ--EIDPEEYEKALSSIKEKNDIADRK-........RDAMNRFISIVHIFLTFIVKKPLHPVGMIFPGGLKITED....GTFYYCPVKDK..QTETGISFCEFCICKD-s.
F0TAZ0_METSL/15-175             .....................t-RVELLEKLKKEAKNIHIKDIMNACNFLFEEGKYVQ..PSYREKFHNAYLKGFILRIKEVKD.----DKCTIQ-QLVDMDELKKSLKLLEEQEIDLLRNHp......hDPNFSKIYQIISIYTTFVLEEPIHVVGSEFPGGFKVKFE....NKTYYCPVKDK..QKDNPGAVCGFCIAEQD..
F6D7G3_METSW/41-199             .....................s-KNELLSVLKKEAYCIHIIDIMMADTFLRADARYVP..ARYRDELLKISTKAFFTRIKDIKD.----DKKHYK-GNVDVNKLKEFLNALKKQRDDAKVNM........ELCFLKIARIISVYTTFIREESIHPVGTPFPGGFKVRYD....DGNYLCPVKEV..QKKNPNALCRFCISKQD..
Y666_METKA/2-137                .........lrrdawrqarfvh-----------------------------------P..RSYREKILRSLFFALTARINQMRR.---LDPEEYPE--DPIEGYDRFLEIVREYAEDPDYD-........SPLLLLYESLSAAYAIFLRGEPVHPPGTEFPGVGKVRRT....DDCYYCPIKER..REDQPGSFCTLCPAEQD..
E1RH52_METP4/29-200             ......................TKGELAEAIASEIIKYSLYELQVIGGKVRQEIDKLP..SPYREKVRPFFQQQLFDVYNRLMSmQRSGGFSRMKGKIDDPALFAEFLDAVPAGCLKDPEHSgtd.fnfgDPIKSLFYYLLCCFTMFVMDEPGHPVGTPFPGGFIVEKR....ADGYYCPIRDK..EEEVPFSICNFCPAKQM..
K4MED9_9EURY/2-160              .....................d-STDLLNSLQKEARKISNEDICLARAAVVDSVQDLP..GKYRKAYSSDYFTYLYEAFQELRT.CKT----SDKAEPVDDEEHRDLLTRISQQKDKSNPR-........QRAFLRFVAVVTPYLVFVAKRTIHPPGMIFPGGLMITSQ....GGEYYCPVKSK..QSGVELALCDFCKCRD-s.
K2RQ20_METFO/13-172             .....................s-KNDLLEALKGEANQVHINDFIKTCSFLKKNMEHVH..PHYQEEYIKMYTEGYLKGYIDVKK.----DITSYS-GLVDVAELAEAIHLLQKQEKLMEAEY.......gKNRSFKPYMIMSLYTTFILEEPVHPVDTPFPGGLKVRKD....QDIYYCPVKEN..NEDNPLAVCGFCIALQ-e.
R7PVU2_9EURY/3-149              askllneirenlkdypidylkn--------------------------------KVTD..DRYKDPLTKSLAKYNSGVYDEIYE.----KELEND-FKINDGVVQKIKGDINFYFDKYAPN-........DNETKEFTKYISLYLALIVKKPLHPYGND-PKKDEVYMK....NNSYYCKGRAK..FIKDQKSLCRYCICKN-p.
D7E9K9_METEZ/2-160              .....................d-TSQLFQCLKKNALKISIHDLMKAKAYIEYNNRNLP..EKYQKDYTQNLFEYIFNTLIEIKN.----KNSVDSVEHIDENVFKDLVEKINRLNENYSPE-........QKIFNRLIKIVSLYLVFIAKKPIHPEGMIFPGGFKITKE....SGVYYCPVKNK..QSGIEFALCDFCVCRD-k.
A4FZ14_METM5/5-165              .....................n-SKELFKNLKEKARDYPVSDLIKVKYYFDREMKIVL..KKYRENFVYSYFGLFYETLMEIKN.-KSESEIPTF--DLDEVEIQKLNERIDFVSLELKTEK.......gREEIITLEKIVYPYLVFISKKPLHHLSLRFPGGNTIIEK....KGIYFCPIRDA..QEN-DLGICEFCCCKD-y.
F8ANK7_METOI/2-159              .....................k-SKELLKKLKEDASKFSIHDLMNVRLFLEKDMEYLP..KEYKESYLKDQIIYFINTLKELRK.-KNEEELED--FEIDEDILNKLYNRINQFKTNTKG--........EDSFIKLSHIVTPYLIFIAKKPLHPIGMRFPGGKRIIEK....NGIYYCPVKNR..QKN-EYSLCEFCICK--gi
U6EC76_9EURY/13-172             .....................s-KNDLLDALKDEANQLHINDFMKTCSFLKKSMKYVH..PHYQEEYIKMYTEGYLKGYRDVKN.----DKNSYE-GKLNCEELFEAVKLLEGQEELMKKEF.......gEDRSFKPYMILSLYTTFILEEPVHPVGTPFPGGLKVREE....ESIYYCPVKDN..NQNNPLAVCGFCIAHQE..
A3CXE2_METMJ/58-229             ......................TKGDLGLLLAEEVSRYSLMDLQIIGGRLHAEIIRLP..EPYRKQVHPFITEQLFGAHHQLLAmHRSGRFRSMTEPITDRATFVEFCNMIPDGCFRRDESPeri.pfrnTPRHRAFYYLVSAFTIFVLDRPGHPVGMPFPGGFRVEEH....NGSFYCLIRDR..EKDVPFSICNFCPALQT..
K6U1R5_9EURY/15-175             .....................s-KNDLLEALKGEANQVYINDFIKTCSFLKKNMEHVH..PHYQEEYIKMYTEGYLKGYRDVKN.----DKTSYS-GQVDVLELEESIQLLENQEQLMEAEFg......kNNRSFKPYLIMSLYTTFILEEPVHPVGTPFPGGLKVRKD....KNIYYCPVKEN..NEDNPLAVCGFCIAQQE..
A5UJ91_METS3/3-149              askllneirenlkdypidylkn--------------------------------KVTD..DRYKDPLTKSLAKYNSGVYDEIYE.----KELEND-FKINDGVVQKIKGDINFYFDKYAPN-........DNETKEFTKYISLYLALIVKKPLHPYGND-PKKDEVYMK....NNSYYCKGRAK..FIKDQKSLCRYCICKN-p.
A6UW08_META3/2-163              ......................NKMELLDILKKLSNNFGVYELMNVRIFLEKDMAHVP..KEYRTHYINSYIGYYSKLLNNMKTiIPKNNNIGDKDCPIDEEKYNKLMDRIEQLKPEDSK--........GSSFIKLSKIVVPYLVFIEGIPLHPVGMKFPGGNRVIKK....NNNYYCPVKNK..QDN-KYSLCEFCICKD-y.
K2RTT9_METFO/15-174             ......................TKDQLLCVIKEDARKFNIDDIQQCSLQIQQEAECIH..TSYKKEYIKAEIG-FLIRIREVKD.----DNFCYD-GQVDMDELNTAIDILEEQEKMVKDMEe......mNPSLLQIYSIISLYTTFIKDEPIHQVGTLFPGGFTVKKE....GSKYTCPVKDN..NDDNPLALCPFCIAEQD..
R9SM74_9EURY/15-177             .....................f-KQDLVEILKDKSKTISVFDQMNCTNELWEGLKFVQ..GKHKKDFFETYCKYFILRINDIKD.----DKNDYDSETFDFDEFVKFVVMLENNYYEIGDKDv.....mrSEAFRSIYAIISLYTTFVLEEPIHPVGTKFPGELEVEYD....DGVYYCPVKEN..NVDNPKAICQFCIAEQ-l.
B9AD87_METSM/3-149              askllneirenlkdypidylkn--------------------------------KVTD..DRYKDPLTKSLAKYNSGVYDEIYE.----KELEND-FKINDGVVQKIKGDINFYFDKYAPN-........DNETKEFTKYISLYLALIVKKPLHPYGND-PKKDEVYMK....NNSYYCKGRAK..FIKDQKSLCRYCICKN-p.
K2QA68_METFO/15-173             .....................s-KDYLFKVLKNEARSIHIQDIMRGSNFLKEDVKFMP..PQERDDIISRFTKALFVRIKNIKD.----DRSNYS-GYVDSYKLQNFLKIQNENIKNSQSLD........EKCFYIIARVVSTYTAFVKEEPIHPLGTRFPGGFTLRLV....EGVYLCPVKDK..QQDTPSALCRFCVSVQD..
B8GKS1_METPE/34-196             ......................TRGELGTALAAIVLLYTPADIRQMQRNFKTKIRDID..EDYREPLYLKVTEHLLGTYQQIRLlSQQGAFSRMDIPVSPEN--SRYWAMVAAACSARAEEK........GPRLAFLNYLLAGFCIFVLDEPAHPVGTPFPGGDTVECE....DGIYYCPVREK..SSEIDAGFCGFCPALQT..
K2QDS7_METFO/16-175             .....................h-RNDLLSRLKAEARLITIQDLMQASYFLIEDAQYIQ..GSYREEYIKAYTMAFIARVKEVKE.-----HPEYDNTSLDMQEVKNALKLLLEQEKQVEDDG.......fDPVFFQIYKIISLYTTFILEEPVHPVGTSFPGGLKVQYD....GEKFLCPVKER..QKDNPGAVCGFCIAQQD..
K6U060_9EURY/16-176             .....................h-REKLLTLLKMESQLITLQDIMQASSFLIEDARYVQ..GSYRKEYLKAYTLAFITRIKEVKE.-----HQPDDNKYLDVQEVQEAISLLLKQEREVTGADg......fDPAFFQIYKIISIYTTFILEEPVHPVGTPFPGGLKVKYD....GEKFLCPVKER..QKDNPGAVCGFCVAQQD..
B9AH65_METSM/20-180             ......................TKTELLKLLKKYCKIISPYDLMLATARMREEGKYVQ..ANYREKYLEVYVKYFIMRVKEILD.-----NNNYLDEAIDKESFDESFNLLKYQFEKERNYSi......eEDKFPLIYIITALYTTFILEEPIHPVGTEFPGSLKVEEK....NEEFYCPVKDK..QKDNANAICNLCLAEQT..
D9PX50_METTM/12-170             ......................TKMELLEMVKKEASSVHIKDVMDASVYLREDAKYMP..PREQKEFIERFTRAFFNRIRDIKN.----DKNIYP-GDVDTEKLAEFIGFLDEQLRRARSRP........ERCFQRIARIITIYVTFVREEPVHPVGTRFPGGLRVRRV....GDVFYCPVKDR..QISTPTALCRFCVSRQD..
D3E3I4_METRM/20-177             ...................skl----FLEVLKEHSGTISVYDLMSVTAELREDTKYVQ..DKYREETNAVYVKYFLGRIKNIRD.----DNNQYD-GSIDKDDFIESVATLKSYQEGESKTS........KTKFPLIYAIVSLYTTYILEEPIHPVGTPFPGSLKVTQK....NGVFYCPVKEA..NLESPNAVCKMCIAEQ-l.
Y909_METM5/2-159                .....................k-SRKFFSKLKEESYDVSIFDLMNAKVYLEKDMAYLP..EDYKKGYLEDFFTFFPEVLKEIRN.-KTEEELEDF--EIEEEEIRKVDLRLFSMGSKRTG--........RDSYEKLVKTVINYLIFINKRPLHALTTRFPGGKQIIEK....NGNYYCPIKNA..QSN-ELSICEFCICKD-l.
T2GHJ4_METTF/3-152              ....................gs--DALIMALRNMAATLGVYDLMEVRVFLERSCRFVQ..ERYRAIYVDAYMSMVVDSVLDLKA.----GFSGTPEMDDARYSLRDALKRLD----------........EIHAPEIVGLTVLYRTYVKGEPLHPPGTPFPGGFEVEKK....DGVHYCPVKDK..QSDNPEALCDICIARQS..
E1RKK9_METP4/41-212             ......................TKGELGSILAAELADYNNTDLQVIGGWLYAEICRLP..SPYREQVSPYLKDWLFGAYHKLLLyQRTARFSTMSESIRDRETFLAFCRMLPEGCLQRDESTqkl.pfryTLKHRCFYYIVSAFTIFVLDNPGHPVGMPFPGGFKVEER....DGRFLCPIRDH..EKDLPFSICNFCPAIQN..
L0HI22_METFS/76-238             ......................TRGELGERIAGLVLLYSPSDIQQMKRNFETKVRDLD..PAYRERLTAKITEYLLGTCQRIRLdNQQGVYKTLKQPVLPAQ--KNYWEMVARQCGDEEGGD........LPVIRFLKYLLAGYSMLVLEEPGHAVGTPFPGGDEVEYT....GGVYYCPVREK..ASDVDAALCPFCPAKQT..
B8GKT1_METPE/36-208             ......................TRGELGALIAEVALSYSVFELQVIGGHLRREVAALP..SPYREAIDPYFTAQIFGAHHHLLLmHRSGAFLRMQTPIADPTLFADFLAMIPASCLRSDDERpgvsghlrTPRHRLFYYLMTGFMIFVLGRPGHPVGMPFPGGFFVKEE....GRRFLCPIRDK..EKDLPFSICNFCPAEQ-i.
F0TAZ1_METSL/15-173             .....................s-RNELKDVVKSEAGNIHIKDIMLAASFLRDDAQYMP..KSYRDDYIERFSKSFFSRVKEIKD.----DKKNYP-GDVNRKDLVEFLELLDEQSKNARTQQ........EKCFVKIARIISTYTTFVCQEPIHPVGTKFPGGFVLHIE....NGNYMCPVKQR..QMKNPSALCKFCVSVQD..
A6USE8_METVS/2-159              .....................n-SRKFFRKLKEECFEISIFDIMNAKIYLEKDMLYVP..LDYKDKYIEDFFTYFPKILLEIKK.---KNELEIENFEIPNESIETVNSRIFKVGSKKSG--........EIYFKKLVKTVLSYLIFIDKKPLHAVTTRFPGGKKIILK....DGKYYCPIKDS..QSN-GLSLCEFCICED-i.
D7DU54_METV3/2-156              ....................di--KTLLTDLKDLSFEISIYDFINAKSELEKELKYLP..EEYKQCYIDDFFTFFPKIIKEIKS.---LDLNSIETFEINDEDLKKLIDRLEVLSNK-----........ERKSYKIYRIVIPYLVFFAKKPLHALTTKFPGKKSIVSK....KGVYYCPIKEA..QKN-DLSICEFCICKD-i.
B8GII9_METPE/31-202             ......................TKGELGVILGEEISRYSMQDLQVIGGRFVADMAGLP..KEFHNELRPRLAEGLFGAHHQIVTlYRSGKFLSMAAPIAHPETFRRFCRMIPYGCLHWDEHVeqt.pfpyTERHRLFYYLISAFSMFVMDRPGHPVGTPFPGGSHVEEQ....NGTLYCPVRDR..EKEVSFSLCNYCPALQT..
H1YYU4_9EURY/19-191             .....................m-RGALAEYLAVELLKFSMYDLQMIGARVRYDIEILP..EIYRKKLRPYAEEWFFGRYHQLITkYRDGDFSKYSGPVHDIDTYRNFCMMIPEGCFKSDVNLpsfipddrYPSFSLFYYLLNAYAMFVLEEPGHPVGTPFPGGAVVRKT....AGKYYCPIREK..EEEIPNSICNFCPALQD..
D3E0U5_METRM/2-158              ...........kssvlleeike--------------NIQNYDIDHIKEN-------LK..KEDINPISKQVSEFNLKNYDEIME.---TKISEEDDFEISDEMIYSMKNEIDLFFKGCSPES........EDSFKKFIESICLYLSLIAKKPLHPVGMDFKNGNTVHEEiedgNTVYYCDLKEYfgKQEKDYYTCKFCVCK--tv
K6U173_9EURY/15-174             ......................TKKELLCILREDARKFNLNDIQQCSLQIQQEAECIH..TNYKIEYIKAEIG-FLIRIREVKD.----DNLYYA-GPVDVKELNTAIGILEEQEKMVKDTEe......mNPAILKIYSIISLYTTFIKDEPIHQVGTLFPGGFMVKKE....GNKYTCPVKDN..NDDNPLALCPFCIAEQD..
B8GG14_METPE/6-153              ...............lllriqs-------------------DLEEISGYTSRIAVEIPlrSEEPSTIISRLAVYNYQTYLEIRS.-LSGIAP---DFEIDEKRLGQMYSVLAHYLDRYAPG-........NEDLHCYVTAISIYLTFIAHKPLHPPG-SFSEEIQIVRR....GSLYYCSGRRK..FIRDNPSLCRFCVCQ--pa
K6T3P0_9EURY/15-173             .....................s-KDKLFKVLKEEARSIHIQDIMRGSNFLKEDVKFMP..PRERKDIIARFTKALFVRIKDIKD.----DHSHYS-GYVDPDKLKNFLNIQNENIQNSQNLD........EKCFYLIARVVSTYTAFVKEEPIHPVGTRFPGGFTLRLV....DGVFLCPVKDK..QKDTPSALCRFCVSVQD..
Y811_METTH/3-152                ....................gs--DALIMALRNMAATLGVYDLMEVRVFLERSCRFVQ..ERYRAIYVDAYMSMVVDSVLDLKA.----GFSGTPEMDDARYSLRDALKRLD----------........EINAPTIVGLTVLYRTYVKGEPLHPPGTPFPGGFEVEKK....DGVHYCPVKDK..QSDNPEALCDICIARQS..
D5VU42_METIM/2-152              .....................k-ATELLKKLKEEAKNFSIYDIAKVRAFLERDAKYLP..KNYREKYVNKMLEHFLKSLKEVKE.----YKLKED-YEIDEKKLKALLDRIENSGY------........DETFIRLSKIVCPFLVFIAKKPIHPLDLEFPGGLKIIKK....GDKYYCPVKEK..QKN-QFSLCPFCICQ--p.
L0HGV6_METFS/29-200             ......................TRGELGEILASEAGKYSLFDLQIIGGRLNAEIEKLP..SPYREAVAPYFRDQLFSAHHRLLSmYRSGAFCRLTGPIRDRERFEAFCTMLPSGLYAWNDAGern.pyfqNPKNRFFYYLVAAFTMFVLEEPGHPVGMPFPGGFTVEQR....GSDYYCLIRDK..EKDVFYSICNFCPARQ-a.
A5UK44_METS3/20-180             ......................TKNELLKLLKKYCKIISPYDLMLATARMREEGKYVQ..ANYREKYLEVYVKYFIMRVKEILD.-----NNNYLDEAIDKESFDESFNLLKYQFEKERNYSi......eEDKFPLIYIITALYTTFILEEPIHPVGTEFPGSLKVEEK....NGEFYCPVKDK..QKDNENAICNLCLAEQT..
N6VQJ6_9EURY/2-158              .....................k-AKELLKKLKEKAENFSIYDIIAIKCFIEKDAKYLP..EKYKEDYINAMIKYYIDTLNEIKS.---KEICE--DYEIDEKKLNELINRIESFKKYNSEE-........EKKFIELSKIICPYLLFIAKKPFHPEYLIFPGGLKIIKD....NNIYYCPVKEK..QLN-EYSLCEFCVAK--pi
J0S9P9_9EURY/35-197             .....................t-KLELLGAISDAAARFSVTDLEAMMKNFEEKTRDLD..PAYRRLLLPRIHASIFGSYHALMLlCTDDPALEDG-P--VRPSLGAYAAMVQEACRRRAQAE.......nPLELYFLKYLLAAFTMYVLEEPAHPVGTPFPGGLAVYRE....GDSYYCPVRDK..SDDIPFSLCPFCPARQD..
A7IAC9_METB6/28-199             ......................TKQDLGVHLARAAGEYTLADLQVIGGRLFAEVDALP..EPYRSRVRPYFHEQIFGAHHRLLLmYRSGVFRQDQDPIRDRETFDKFCAMIPDGCFTWDEQAert.pfrySPRHRLFYYLMAAFTMFVLDRPGHPVGMPFPGGFTVEER....NGNCYCLIRDR..EKEVFFSICNFCPAKQN..
C7P6B7_METFA/2-160              .....................k-AKELFKNLKKELDNFSIYDIMMIRSFIEKDAKYLP..PQYKNHYVEAMMKYLIETFNEIKK.-KKVDEIED--EEIDEKKLNKMLNRIENFRKYYSSD-........EEGFINLSKILCPYLAFIAKKPLHPEYLTFPGNVKIIKK....GNDYYCPVKNK..QLN-EYSLCEFCVAKS-m.
A2STY9_METLZ/48-217             .................snqaa-----AEIIGRALSAYTVFDLQYIGGYLKCEAERLP..DPYRRLYRPYCMD-LFDQYHAFMQdFRPGIVC--HGPLPDLDLWKKYWTGVPEYCFQDAVSSqsprpvqnHPLSKFFYRLVFAYVMFVKGGCGHPVGMPFPGGFRIRQA....GDIVYCPIRDR..EKDLPQALCNYCPAKQD..
H1Z2H4_9EURY/18-178             ......................TRGELGRAIAAIVNGYSTLDLRRMQWNFSGSVKGIE..PSYKKKLEKMITGHLHETWENIRLmNQQGSFSQMKD--LLPENNREFWEMVALKCSDKDG--........STRIRFLKFLLAGFCIFVKKIPPHPVGMPFPGGDSVQFI....EGIYYCPVREK..ANDVDSALCPFCPALQT..
A3CTH3_METMJ/19-180             ......................TQRELAKILYHAVSGYSLFDLQEMRGRVERDLRSVP..AGYRRRLYPSVMEQIFETHHTLIVaGRRGD--PGDGERLLPGEFQDFCDMVEKTCLREDEG-........ERHLELLYFLLAAFNIFVLDRPAHPVGTPFPGGFEVEVR....NGEYLCPVREK..ADDVENALCPYCPAKQS..
D2ZMX5_METSM/1-54               ....................mh------------------------------------..------------------------.------------------LKKYIFNLNETLDPHKS--........SAEFCIIVFLSILYVNYILEEPVHPEGLNFQNHK-----....-----------..-----------------k.
K4KSS2_9FIRM/1-74               ....................md------------------------------------..------------------------.-------------------------------ENAPG-........QIDLKQYIRIISTYLAFISKKPLHPLGMIMQGTEKIIKQ....NDKYYCPMRRA..QIKGKLSLCIYCVCRD-i.
D2ZRF0_METSM/3-149              askllneirenlkdypidylkn--------------------------------KVTD..DRYKDPLTKSLAKYNSGVYDEIYE.----KELEND-FKINDGVVQKIKGDINFYFDKYAPN-........DNETKEFTKYISLYLALIVKKPLHPYGND-PKEDEVYMK....NNSYYCKGRAK..FIKDKKSLCRYCICKN-p.
#=GC seq_cons                   .....................p.pt-LhphLpccstpholhDlhthpshlcp-hchls..tpY+cchhpthhphhhtshc-l+s.....phtphp...lDpcphpchhphlpphtpptpst.........ctphhplhtllusYhhFlhccPlHPlGh.FPGGhpVpcc....sspYYCPlK-+..ppcsshulCpFClucp...
//
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