GenomeNet

Database: Pfam
Entry: DUF2118
LinkDB: DUF2118
Original site: DUF2118 
#=GF ID   DUF2118
#=GF AC   PF09891.8
#=GF DE   Uncharacterized protein conserved in archaea (DUF2118)
#=GF AU   COGs, Finn RD, Sammut SJ
#=GF SE   COGs (COG4072)
#=GF GA   20.50 20.50;
#=GF TC   20.50 20.50;
#=GF NC   20.40 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019217;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   30
#=GS B8D6F0_DESK1/4-152       AC B8D6F0.1
#=GS H3ZR63_THELN/2-163       AC H3ZR63.1
#=GS Q9YB32_AERPE/20-168      AC Q9YB32.1
#=GS F0LKP5_THEBM/2-164       AC F0LKP5.1
#=GS A0A075LQD5_9EURY/2-163   AC A0A075LQD5.1
#=GS F8AHU2_PYRYC/2-164       AC F8AHU2.1
#=GS A0A0U3EEE1_9CREN/4-149   AC A0A0U3EEE1.1
#=GS A2BK90_HYPBU/13-160      AC A2BK90.1
#=GS D3LV55_9FIRM/20-96       AC D3LV55.1
#=GS D7DV81_METV3/5-160       AC D7DV81.1
#=GS B6YUI5_THEON/2-163       AC B6YUI5.1
#=GS A3DMR4_STAMF/4-160       AC A3DMR4.1
#=GS C6A019_THESM/2-163       AC C6A019.1
#=GS Q8TXA2_METKA/1-162       AC Q8TXA2.1
#=GS A8ABP2_IGNH4/4-149       AC A8ABP2.1
#=GS Q6M171_METMP/1-150       AC Q6M171.1
#=GS Q6M171_METMP/1-150       DR PDB; 3D4R D; 1-150;
#=GS Q6M171_METMP/1-150       DR PDB; 3D4R B; 1-150;
#=GS Q6M171_METMP/1-150       DR PDB; 3D4R E; 1-150;
#=GS Q6M171_METMP/1-150       DR PDB; 3D4R A; 1-150;
#=GS Q6M171_METMP/1-150       DR PDB; 3D4R F; 1-150;
#=GS Q6M171_METMP/1-150       DR PDB; 3D4R C; 1-150;
#=GS D5VSA2_METIM/1-151       AC D5VSA2.1
#=GS Q9UZF3_PYRAB/2-163       AC Q9UZF3.1
#=GS A0A0V8RTM4_PYROC/12-160  AC A0A0V8RTM4.1
#=GS Q8U1K5_PYRFU/2-163       AC Q8U1K5.1
#=GS G0EE93_PYRF1/11-160      AC G0EE93.1
#=GS A0A0S8H0Q2_9BACT/1-98    AC A0A0S8H0Q2.1
#=GS D5U3E6_THEAM/4-158       AC D5U3E6.1
#=GS A0A0P0N5J5_9CREN/13-161  AC A0A0P0N5J5.1
#=GS Q5JEN4_THEKO/2-163       AC Q5JEN4.1
#=GS C5A383_THEGJ/2-163       AC C5A383.1
#=GS Y859_METJA/4-156         AC Q58269.1
#=GS R7PSJ1_9FIRM/21-94       AC R7PSJ1.1
#=GS I0A0D6_FERFK/6-145       AC I0A0D6.1
#=GS E0SQA2_IGNAA/15-153      AC E0SQA2.1
B8D6F0_DESK1/4-152                  ....................................YSFPQLFVEDVDSE................--RIICLKNSEYAwAGI..PEK......N.NCTKYY...GSIPYEE-ILKYID.LEKAIL.K.RSTILFNT...gEPSKALFFSENTQLCLQEAKG.RRVFYIGSM-KHVRKNDLIAYIVTGKNEVRNIYSTCEGFI..LAVIDLTW...ERPERIIVVVA--ie..........................
H3ZR63_THELN/2-163                  ....................................EKLPQLFVEAEFEEcfegdea.kvdciiiqDNIEIRLQKGQKL.PEF..IDV......K.KAKFLR...-KEIYDR-FHFYVD.KYEHKM.L.CDARIVLP....DRRTEIRLYEGDELMLLPVEG.FVSTIIAGVGNRVRKSDAFAAVTTKKGEVHYLKPPKNGVV..VYIDEFTN...--RPHYIYYILPE............................
Q9YB32_AERPE/20-168                 ....................................YRFPELYLEGYVSE................---RAIWVDEEEG.KYY..RRP......V.EGLKRY...GLAVYEHAIKEAID.LVGSRV.S.RGFVVVIP...wKGMRGLMLREGTRVKLVEAAG.VQVSHYSLEGTRVGERSVLSYVLTGKGETRTLRAGVEGVV..AIILTDHN...RQPPAYIYVIADE............................
F0LKP5_THEBM/2-164                  ....................................ERIPQLYVESSYEEcfdkegrakvnciiiqGNVEVRLKKGEKI.PEF..IDI......E.RAKILK...-KEVYDR-FHFYVD.KYEHKM.L.CDAIVVLP....DRRTEIRLYKGDELMILPVEG.YVSTLIAGVGNRVRKSDAFAAVTTKKGEVHYLKPPKNGVV..VFIDEFTN...--RPHYLYYLLPE............................
A0A075LQD5_9EURY/2-163              ...................................e-KMPMLFVEKSYDEcfeeeka.kneciiiqDNIEVKLSKGDKL.PNF..IDK......N.KAKFLT...-KEVYDR-FHLYVD.KNEMKM.L.RDAIIVLP....GRRTQIKLKKGDKLMILPVEG.FVSTLIAGVGNRVRKSDAFAAVTTKKGEVHYLKPPKSGVV..VYIDEFTN...--RPHYLYYLLPE............................
F8AHU2_PYRYC/2-164                  ...................................r-RLPQLFVEASYEEcfdeegkakvdciviqGNVEVRMRKGEKL.PAF..IDP......K.EAKFLA...-KEVYDR-FHFYVD.QYEHRM.R.VDAIIVLP....DRRTEIRLQKGDELLLLPVEG.YVVTLIADVGNRVRTGDAFAAVTTRKGEVHYMKPPKPGVV..VYIDEFTN...--RPNYVYYILPE............................
A0A0U3EEE1_9CREN/4-149              ....................................YEFPKLFVEGIDGE................----EYLEITDNS.AKI..SKE......P.SSPK-L...GKVPLEIDLEEIVD.LLGERV.K.RSFAVYNP....RKKVVIYVREGTPIKILRVDH.KKVLIELSEGDEINLDSTYAHGITSKGEYRRFRSKVKGIV..VLVHWKPL...GGRDIYHVIVAE-r...........................
A2BK90_HYPBU/13-160                 ....................................YHIPRIYIEGIGSD................----EYLELVDST.ARR..TDR......C.SGRRCF...GKAIYGTLLDEIAD.LLAKKA.T.RSFIVVLP...pDYRKGLLVEAGSYLEPVPLEG.MRVVIHVCEGDRVEEGSTLGFIATRKFEVRHIRSHVEGVV..VYIYSSPE...GPPDRNIVFIAPE............................
D3LV55_9FIRM/20-96                  .....................tpvmaeevscasvlt--------------................-------------.---..---......-.------...--------------.------.-.--------....---------------------.GTVVSVAAVGTQVKEGDVLLTVASLAGPMPAIRAQRDGVV..KVVKTAPG..aEVQQGAAVIIV--de..........................
D7DV81_METV3/5-160                  ....................................MKIPKLYVENNIFEd..............nEPCEKIAVSEKEI.IFLdsDEV......V.DNYKNT...HKILYKVRYDDIRS.YIDNDVlK.KDIFVKYP....GNHTFTHIKAGTYITCVLADS.KTTYPILDAGSVVLRDGILATLKSNKGVIRYLKSPVSGTV..FFMNEIFE...GNNSIYLFAIVE-n...........................
B6YUI5_THEON/2-163                  ...................................e-KMPKLYVEVPKEGciennka.srdcliimNNVEVWLRKGESV.PEF..IDV......E.KAKFLA...-KEVYDR-FYLHVD.RLKGRM.E.VDAVLVLP....DGRTRIYLRKGDELLLLPVEG.YTKTLIANVGNRVRTGDAFAAVTTKKGEVHYLKPPKTGTV..VFIDEITN...--RPHYVYYILPE............................
A3DMR4_STAMF/4-160                  ....................................YRYPEVFVEGVESD................---KYVLEINEHY.ILV..LTKedlekyV.NYKRVF...GHIIYEH-IINYID.LVKPAT.K.KAFIVIPEysgeKEMNGFLIDENKKLCLIEVKG.IQPYVFPREGDEIEERDKVAYIITGKGEVRTIRSPCKGVV..LLVINFPW...EKPEKYVLAVV--nk..........................
C6A019_THESM/2-163                  ....................................EKIPQLFVESNLEEcvdgeka.rvdcriiqDNIEVKVKKGEKI.PEF..IDP......K.RAKFMK...-KEVYDR-FHFYVD.KYEHKM.M.CNAIIILP....DRRTEIRLYKGDELMLLPVEG.YVSSIIAGVGNRVRKSDAFAAITTKKGEVHYLKPPKTGVV..VYIDEFTN...--RPHYVYYILPE............................
Q8TXA2_METKA/1-162                  ....................................MALPRIYVETDEVPesgk.......illtdPEFEVIVRSRELA.EKI..AEE......L.DEPIFY...EQVVYEE-ARSVFD.VPEAKV.T.RHVVIEPV....DRRSLVFLKPGDRVYQIPVEG.YVVTPIADVGDRLRKGDPLAAVTTRSGNVRYVEAPQDCLV..VYVCEQPAirtQRRPNYEYYIAPT............................
A8ABP2_IGNH4/4-149                  ....................................YKFPRLFVEGKEGE................---EYAVVEGDEV.VFV..KEK......V.PGAL--...GKVPYEIPLDEIVD.KLKEEA.K.VTFLIHLP....NEDKAILVPKGSKVKLFKVSH.VKVGVTVKEGDELEEGDTYAYGLTGKGEVRRFRSIVKGKV..VMVHWEPY...GGRDDYHVLVVPE............................
Q6M171_METMP/1-150                  ....................................MKIPKIYVEGELND................-GDRVAIEKDGNA.IIF..LEK......D.EEYSGN...GKLLYQVIYDDLAKyMSLDTL.K.KDVLIQYP....DKHTFTYLKAGTKLISVPAEG.YKVYPIMDFGFRVLKGYRLATLESKKGDLRYVNSPVSGTV..IFMNEIPS...-ERANYVFYMLEE............................
#=GR Q6M171_METMP/1-150       SS    ....................................SE--EEEEET--SS................-S-EEEEEGGGTE.EEE..E-T......T.----SS...SEEEEEESSS-GGGGEETTEE.S.S-EEEEET....TSSEEEEE-TT-B-EEEEEES.SEEEESS-TSEEE-TT-EEEEEE-TTS-EEEEE-SSSEEE..EEEEEETT...-CEEEEEEEEEE-............................
D5VSA2_METIM/1-151                  ....................................MRIPKLYVEGEEGE................--EKVVIEKDGKI.IRF..LDK......G.ESYEGE...GKVLGKVIYDDFPNyILMGEA.T.RDMLIVYEv..gGLKKIMYLKKGTKLLEVPAEG.YKVYPIVDHGCRILEGHRLAALQSRKGDIRFVNTPVNGIV..VFLREVPC...-KRENYVFYILPD............................
Q9UZF3_PYRAB/2-163                  ...................................s-RLPQLYVEVPKEEclegrkv.kheciiiqDNLEVKLGEGDEI.PDF..VDL......D.RAKFLA...-KEIYDR-FHFYVD.QYEHRM.K.VDAIIVYP....DRRTKIYLKKGDELLLLPVEG.YVVTLIADVGNRVRKGDAFAAVTTRKGEVHYLKPPRPGTV..VYIDEFTN...--RPHYVYYILPE............................
A0A0V8RTM4_PYROC/12-160             ...................................y-LIPQLFIEGLESS................---DYLVLRNGVA.QRS..RGC......P.EGERCF...GKAIYGVELESIVD.LVAKKS.R.RSFIVVLP...rEYRRGLLVEAGSPVEPIPLEG.MRVVLEVCEGSRVGVQSTLGFIATRKLEVRRIRSHVKGVV..VYIYSSPE...AGPDKNIVLVAPE............................
Q8U1K5_PYRFU/2-163                  ...................................s-RTPQLYVEVPKEEclegrrv.khdciviqDNIEVRLREGEEV.PEF..IQV......D.KAKFLA...-KEIYDR-FHFYVD.HYEHRM.K.VDAIIVYP....DRRTKIYLKKGDELLLLPVEG.YVVTLIADVGNRVRKGDAFAAVTTRKGEVHYLKPPKPGTV..VYIDEFTN...--RPHYIYYILPE............................
G0EE93_PYRF1/11-160                 ...................................y-LIPRLYIEGIKGD................---EYLVESGEGV.YKR..SKS......CpSGSRCY...GKAIYGVELDSILD.LLEKKV.K.RSFIVEPG...dKPGEGILVESGVHAEPIPVSG.KRAVIEVLEGDEVKEGDVLGLIVTGKYELRKVRSHVDGIV..VYIYSSPM...GPPDENIVFIVP-r...........................
A0A0S8H0Q2_9BACT/1-98               ................................mnkk-----------E--................-KEKYKVKLLEKK.KEI..TEK......L.SETYNE...SKEVETGIAQDVVD.KAESSY.T.KEFLLSLSd..tERRQLLMID------------.----------------------------------------..--------...-------------ealrriekceygicqmcgqkiskkrlna
D5U3E6_THEAM/4-158                  ...................................y-FFPEAYVENGLES................-GRSICFKGNDIY.IAF..AKN......A.GTGECVktfVNTPFEK-LVEYMD.LEKPCF.T.RDVIIVHRe.egGYYKGFLIEKGEKLYLLEASG.STIAVSKREGDAVEPHEKIGYIITNKREVRVIKAPLKGIL..LAVIDLTW...EKPEKIIM-----vftge.......................
A0A0P0N5J5_9CREN/13-161             ...................................y-LIPQLFIEGLDSD................----EFLVLRDSI.AKR..SME......CpKDARCF...GKAIYGVELDSIVD.LVAKKC.T.RSFIVVLP...pDYRRGLLVEAGSYVEPIPLEG.MRVAVEVCEGSKVGIEDTIGFIATRKFEVRHIRSHVEGVI..VYIYSSPE...SGPDRNIVLVAP-r...........................
Q5JEN4_THEKO/2-163                  ....................................EKLPKLYVETTQEEcvkdgkt.laecvvimGNVEVWLKENEEL.PDF..IDP......S.RAKFLK...-REVYDR-FYLYVD.RTEQKM.T.ADVILVLP....DGRTRIYLKKGDELMILPVEG.FTKTLIANVGNRVRTGDAFAAVTTRKGEVHYLKPPKTGTV..VFIDEITN...--RPHYLYYILPE............................
C5A383_THEGJ/2-163                  ....................................ERLPRLYVETSFEEcfageka.vedcvvimDNVEVWLGKGEAL.PGF..IDV......E.RSKFLR...-REVYDR-FYLYVD.RVESRM.L.ADAILVLP....DGRTRIYLRKGDELLLLPVEG.FTKTLIANVGNRVRTGDAFAAVTTRKGEVHYLKPPKSGTV..VFIDEITN...--RPHYVYYILPE............................
Y859_METJA/4-156                    ....................................MRIPRLYVENAEKH................EGRKVVIENGGKV.IKF..LDK......D.EEYEGD...GKVLYQVIYDDFDNyVLMGTV.T.KDMIIEYEv..gGVRQITYIKKGTKLLEIPAEG.YKVYPIVDFGCRILGGHRIAALQSRKGDIRFVNTPVNGIV..LFLKEVPA...-KRENYVFYILPE............................
R7PSJ1_9FIRM/21-94                  .......................gesfafvpqmsvl--------------................-------------.---..---......-.------...--------------.------.-.--------....-------------------SG.KTVSVIA-EGTRVKEGDVLVLVDSLVGPVPAARATVDGVV..IEVT----...-------------vgngqiidqndqvavi............
I0A0D6_FERFK/6-145                  .................................yrl--------EDDKKI................PSVKNYLKSNENI.ESK..LDI......S.LDRIAC...EEIIFNN--ISFGE.RNICVS.K.GNFIIKTP....KN--SFLIERNEELKYFIIEA.SQINTRKKPGDSVKKWDEIAVSKSKKGILRRIKIPFEGQI..ILVEQDPT...-YKPERIVFIL--k...........................
E0SQA2_IGNAA/15-153                 ...............vsynsklyvdlekkifcdkpm--------------................-------------.---..---......A.DDNRVF...VEIVYEKLPEIAID.FENNIL.R.IDVAIYIP....SKDIVLFIKRGSNVDILEAQG.KIIIPLVNSGESVESNTKVFYRITKKYETRTHRAETVGLV..VYIGEMFI...-------------gdsekmiavtvge...............
#=GC SS_cons                        ....................................SE--EEEEET--SS................-S-EEEEEGGGTE.EEE..E-T......T.----SS...SEEEEEESSS-GGGGEETTEE.S.S-EEEEET....TSSEEEEE-TT-B-EEEEEES.SEEEESS-TSEEE-TT-EEEEEE-TTS-EEEEE-SSSEEE..EEEEEETT...-CEEEEEEEEEE-............................
#=GC seq_cons                       .....................................+hPpLaVEs..p-...................chhlcps-ph..ph..h-h......s.csphhh....K.lY-p.hc.hlD.hhcpch.p.pshllhhP....ct+ptlhlccGscLhhlPlEG.hplsllss.GsRVccuDshAhlsT+KGEV+hl+sPhsGlV..Valp-hsp.....pscYlhhllPp............................
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