GenomeNet

Database: Pfam
Entry: DUF2118
LinkDB: DUF2118
Original site: DUF2118 
#=GF ID   DUF2118
#=GF AC   PF09891.7
#=GF DE   Uncharacterized protein conserved in archaea (DUF2118)
#=GF AU   COGs, Finn RD, Sammut SJ
#=GF SE   COGs (COG4072)
#=GF GA   20.50 20.50;
#=GF TC   20.50 20.50;
#=GF NC   20.40 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019217;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   22
#=GS B8D6F0_DESK1/4-152   AC B8D6F0.1
#=GS Q9YB32_AERPE/20-168  AC Q9YB32.1
#=GS H3ZR63_THELN/2-163   AC H3ZR63.1
#=GS F0LKP5_THEBM/2-164   AC F0LKP5.1
#=GS F2GB98_ALTMD/25-88   AC F2GB98.2
#=GS A2BK90_HYPBU/13-160  AC A2BK90.1
#=GS Q8U1K5_PYRFU/2-163   AC Q8U1K5.1
#=GS D3LV55_9FIRM/20-96   AC D3LV55.1
#=GS D7DV81_METV3/5-160   AC D7DV81.1
#=GS G0EE93_PYRF1/11-160  AC G0EE93.1
#=GS D5U3E6_THEAM/4-158   AC D5U3E6.1
#=GS Q5JEN4_THEKO/2-163   AC Q5JEN4.1
#=GS A3DMR4_STAMF/4-160   AC A3DMR4.1
#=GS C5A383_THEGJ/2-163   AC C5A383.1
#=GS R7PSJ1_9FIRM/21-94   AC R7PSJ1.1
#=GS Y859_METJA/4-156     AC Q58269.1
#=GS I0A0D6_FERFK/6-145   AC I0A0D6.1
#=GS Q8TXA2_METKA/1-162   AC Q8TXA2.1
#=GS E0SQA2_IGNAA/15-153  AC E0SQA2.1
#=GS A8ABP2_IGNH4/4-149   AC A8ABP2.1
#=GS Q6M171_METMP/1-150   AC Q6M171.1
#=GS Q6M171_METMP/1-150   DR PDB; 3D4R D; 1-150;
#=GS Q6M171_METMP/1-150   DR PDB; 3D4R B; 1-150;
#=GS Q6M171_METMP/1-150   DR PDB; 3D4R E; 1-150;
#=GS Q6M171_METMP/1-150   DR PDB; 3D4R A; 1-150;
#=GS Q6M171_METMP/1-150   DR PDB; 3D4R F; 1-150;
#=GS Q6M171_METMP/1-150   DR PDB; 3D4R C; 1-150;
#=GS D5VSA2_METIM/1-151   AC D5VSA2.1
B8D6F0_DESK1/4-152              ....................................YSFPQLFVEDVDSE................--RIICLKNSEYAwAGI..PEK......N.NCTKYY...GSIPYEE-ILKYID.LEKAIL.K.RSTILFNT...gEPSKALFFSENTQLCLQEAKG.RRVFYIGSM-KHVRKNDLIAYIVTGKNE.VRNIYSTCEGFILAVIDLTW...ERPERIIVVVA--ie........................
Q9YB32_AERPE/20-168             ....................................YRFPELYLEGYVSE................---RAIWVDEEEG.KYY..RRP......V.EGLKRY...GLAVYEHAIKEAID.LVGSRV.S.RGFVVVIP...wKGMRGLMLREGTRVKLVEAAG.VQVSHYSLEGTRVGERSVLSYVLTGKGE.TRTLRAGVEGVVAIILTDHN...RQPPAYIYVIADE..........................
H3ZR63_THELN/2-163              ....................................EKLPQLFVEAEFEEcfegdea.kvdciiiqDNIEIRLQKGQKL.PEF..IDV......K.KAKFLR...-KEIYDR-FHFYVD.KYEHKM.L.CDARIVLP....DRRTEIRLYEGDELMLLPVEG.FVSTIIAGVGNRVRKSDAFAAVTTKKGE.VHYLKPPKNGVVVYIDEFTN...--RPHYIYYILPE..........................
F0LKP5_THEBM/2-164              ....................................ERIPQLYVESSYEEcfdkegrakvnciiiqGNVEVRLKKGEKI.PEF..IDI......E.RAKILK...-KEVYDR-FHFYVD.KYEHKM.L.CDAIVVLP....DRRTEIRLYKGDELMILPVEG.YVSTLIAGVGNRVRKSDAFAAVTTKKGE.VHYLKPPKNGVVVFIDEFTN...--RPHYLYYLLPE..........................
F2GB98_ALTMD/25-88              .............................ktgffka--------------................-------------.---..---......-.------...--------------.------.-.--------....---------------------.-----SVVIGEKVSTGQEIGTVTDYLGNlVETLKSPVDGTVMMVNQMPA...IKDDQSVM-----aigve.....................
A2BK90_HYPBU/13-160             ....................................YHIPRIYIEGIGSD................----EYLELVDST.ARR..TDR......C.SGRRCF...GKAIYGTLLDEIAD.LLAKKA.T.RSFIVVLP...pDYRKGLLVEAGSYLEPVPLEG.MRVVIHVCEGDRVEEGSTLGFIATRKFE.VRHIRSHVEGVVVYIYSSPE...GPPDRNIVFIAPE..........................
Q8U1K5_PYRFU/2-163              ...................................s-RTPQLYVEVPKEEclegrrv.khdciviqDNIEVRLREGEEV.PEF..IQV......D.KAKFLA...-KEIYDR-FHFYVD.HYEHRM.K.VDAIIVYP....DRRTKIYLKKGDELLLLPVEG.YVVTLIADVGNRVRKGDAFAAVTTRKGE.VHYLKPPKPGTVVYIDEFTN...--RPHYIYYILPE..........................
D3LV55_9FIRM/20-96              .....................tpvmaeevscasvlt--------------................-------------.---..---......-.------...--------------.------.-.--------....---------------------.GTVVSVAAVGTQVKEGDVLLTVASLAGP.MPAIRAQRDGVVKVVKTAPG..aEVQQGAAVIIV--de........................
D7DV81_METV3/5-160              ....................................MKIPKLYVENNIFEd..............nEPCEKIAVSEKEI.IFLdsDEV......V.DNYKNT...HKILYKVRYDDIRS.YIDNDVlK.KDIFVKYP....GNHTFTHIKAGTYITCVLADS.KTTYPILDAGSVVLRDGILATLKSNKGV.IRYLKSPVSGTVFFMNEIFE...GNNSIYLFAIVE-n.........................
G0EE93_PYRF1/11-160             ...................................y-LIPRLYIEGIKGD................---EYLVESGEGV.YKR..SKS......CpSGSRCY...GKAIYGVELDSILD.LLEKKV.K.RSFIVEPG...dKPGEGILVESGVHAEPIPVSG.KRAVIEVLEGDEVKEGDVLGLIVTGKYE.LRKVRSHVDGIVVYIYSSPM...GPPDENIVFIVP-r.........................
D5U3E6_THEAM/4-158              ...................................y-FFPEAYVENGLES................-GRSICFKGNDIY.IAF..AKN......A.GTGECVktfVNTPFEK-LVEYMD.LEKPCF.T.RDVIIVHRe.egGYYKGFLIEKGEKLYLLEASG.STIAVSKREGDAVEPHEKIGYIITNKRE.VRVIKAPLKGILLAVIDLTW...EKPEKIIM-----vftge.....................
Q5JEN4_THEKO/2-163              ....................................EKLPKLYVETTQEEcvkdgkt.laecvvimGNVEVWLKENEEL.PDF..IDP......S.RAKFLK...-REVYDR-FYLYVD.RTEQKM.T.ADVILVLP....DGRTRIYLKKGDELMILPVEG.FTKTLIANVGNRVRTGDAFAAVTTRKGE.VHYLKPPKTGTVVFIDEITN...--RPHYLYYILPE..........................
A3DMR4_STAMF/4-160              ....................................YRYPEVFVEGVESD................---KYVLEINEHY.ILV..LTKedlekyV.NYKRVF...GHIIYEH-IINYID.LVKPAT.K.KAFIVIPEysgeKEMNGFLIDENKKLCLIEVKG.IQPYVFPREGDEIEERDKVAYIITGKGE.VRTIRSPCKGVVLLVINFPW...EKPEKYVLAVV--nk........................
C5A383_THEGJ/2-163              ....................................ERLPRLYVETSFEEcfageka.vedcvvimDNVEVWLGKGEAL.PGF..IDV......E.RSKFLR...-REVYDR-FYLYVD.RVESRM.L.ADAILVLP....DGRTRIYLRKGDELLLLPVEG.FTKTLIANVGNRVRTGDAFAAVTTRKGE.VHYLKPPKSGTVVFIDEITN...--RPHYVYYILPE..........................
R7PSJ1_9FIRM/21-94              .......................gesfafvpqmsvl--------------................-------------.---..---......-.------...--------------.------.-.--------....-------------------SG.KTVSVIA-EGTRVKEGDVLVLVDSLVGP.VPAARATVDGVVIEVT----...-------------vgngqiidqndqvavi..........
Y859_METJA/4-156                ....................................MRIPRLYVENAEKH................EGRKVVIENGGKV.IKF..LDK......D.EEYEGD...GKVLYQVIYDDFDNyVLMGTV.T.KDMIIEYEv..gGVRQITYIKKGTKLLEIPAEG.YKVYPIVDFGCRILGGHRIAALQSRKGD.IRFVNTPVNGIVLFLKEVPA...-KRENYVFYILPE..........................
I0A0D6_FERFK/6-145              .................................yrl--------EDDKKI................PSVKNYLKSNENI.ESK..LDI......S.LDRIAC...EEIIFNN--ISFGE.RNICVS.K.GNFIIKTP....KN--SFLIERNEELKYFIIEA.SQINTRKKPGDSVKKWDEIAVSKSKKGI.LRRIKIPFEGQIILVEQDPT...-YKPERIVFIL--k.........................
Q8TXA2_METKA/1-162              ....................................MALPRIYVETDEVPesgk.......illtdPEFEVIVRSRELA.EKI..AEE......L.DEPIFY...EQVVYEE-ARSVFD.VPEAKV.T.RHVVIEPV....DRRSLVFLKPGDRVYQIPVEG.YVVTPIADVGDRLRKGDPLAAVTTRSGN.VRYVEAPQDCLVVYVCEQPAirtQRRPNYEYYIAPT..........................
E0SQA2_IGNAA/15-153             ...............vsynsklyvdlekkifcdkpm--------------................-------------.---..---......A.DDNRVF...VEIVYEKLPEIAID.FENNIL.R.IDVAIYIP....SKDIVLFIKRGSNVDILEAQG.KIIIPLVNSGESVESNTKVFYRITKKYE.TRTHRAETVGLVVYIGEMFI...-------------gdsekmiavtvge.............
A8ABP2_IGNH4/4-149              ....................................YKFPRLFVEGKEGE................---EYAVVEGDEV.VFV..KEK......V.PGAL--...GKVPYEIPLDEIVD.KLKEEA.K.VTFLIHLP....NEDKAILVPKGSKVKLFKVSH.VKVGVTVKEGDELEEGDTYAYGLTGKGE.VRRFRSIVKGKVVMVHWEPY...GGRDDYHVLVVPE..........................
Q6M171_METMP/1-150              ....................................MKIPKIYVEGELND................-GDRVAIEKDGNA.IIF..LEK......D.EEYSGN...GKLLYQVIYDDLAKyMSLDTL.K.KDVLIQYP....DKHTFTYLKAGTKLISVPAEG.YKVYPIMDFGFRVLKGYRLATLESKKGD.LRYVNSPVSGTVIFMNEIPS...-ERANYVFYMLEE..........................
#=GR Q6M171_METMP/1-150   SS    ....................................SE--EEEEET--SS................-S-EEEEEGGGTE.EEE..E-T......T.----SS...SEEEEEESSS-GGGGEETTEE.S.S-EEEEET....TSSEEEEE-TT-B-EEEEEES.SEEEESS-TSEEE-TT-EEEEEE-TTS-.EEEEE-SSSEEEEEEEEETT...-CEEEEEEEEEE-..........................
D5VSA2_METIM/1-151              ....................................MRIPKLYVEGEEGE................--EKVVIEKDGKI.IRF..LDK......G.ESYEGE...GKVLGKVIYDDFPNyILMGEA.T.RDMLIVYEv..gGLKKIMYLKKGTKLLEVPAEG.YKVYPIVDHGCRILEGHRLAALQSRKGD.IRFVNTPVNGIVVFLREVPC...-KRENYVFYILPD..........................
#=GC SS_cons                    ....................................SE--EEEEET--SS................-S-EEEEEGGGTE.EEE..E-T......T.----SS...SEEEEEESSS-GGGGEETTEE.S.S-EEEEET....TSSEEEEE-TT-B-EEEEEES.SEEEESS-TSEEE-TT-EEEEEE-TTS-.EEEEE-SSSEEEEEEEEETT...-CEEEEEEEEEE-..........................
#=GC seq_cons                   .....................................phPplaVEs..t-...................chhlppscth...h..hc.......s.pshhhh....chlYch.h..hhD.h.ttph.p.tshllhhs....s.pphhhlccGsclh.l.scG.hplshlss.Gs+Vccu-tlAhltTpKG-.lRhl+uPhsGhVlhlpphst.....psphlhhll............................
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