GenomeNet

Database: Pfam
Entry: DUF2247
LinkDB: DUF2247
Original site: DUF2247 
#=GF ID   DUF2247
#=GF AC   PF10004.7
#=GF DE   Uncharacterized protein conserved in bacteria (DUF2247)
#=GF AU   COGs, Finn RD, Sammut SJ
#=GF SE   COGs (COG4304)
#=GF GA   25.00 25.00;
#=GF TC   25.30 46.90;
#=GF NC   24.00 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR016630;
#=GF CC   This domain, found in various hypothetical bacterial proteins,
#=GF CC   has no known function.
#=GF SQ   38
#=GS K8VZG2_9ENTR/32-129      AC K8VZG2.1
#=GS A0A068Z3H6_9ENTR/8-164   AC A0A068Z3H6.1
#=GS R5L882_9FIRM/27-178      AC R5L882.1
#=GS D8PDY7_9BACT/6-79        AC D8PDY7.1
#=GS A0A0G0MFB4_9BACT/11-169  AC A0A0G0MFB4.1
#=GS Q5YQU5_NOCFA/15-157      AC Q5YQU5.1
#=GS I8AF88_9BACI/4-155       AC I8AF88.1
#=GS Q97M49_CLOAB/6-167       AC Q97M49.1
#=GS K8EM63_CARML/4-155       AC K8EM63.2
#=GS A0A0B4RBL2_9BACL/18-183  AC A0A0B4RBL2.1
#=GS Q880F1_PSESM/8-164       AC Q880F1.1
#=GS C7M529_CAPOD/2-162       AC C7M529.1
#=GS Q1D2F2_MYXXD/2-148       AC Q1D2F2.1
#=GS A0A0B1YBY4_9BACI/10-160  AC A0A0B1YBY4.1
#=GS Q7DDS4_NEIMB/3-154       AC Q7DDS4.1
#=GS R5NN53_9FIRM/9-150       AC R5NN53.1
#=GS D8MSB5_ERWBE/8-164       AC D8MSB5.1
#=GS A0A0A8JMK0_BACSX/5-168   AC A0A0A8JMK0.1
#=GS D1AI70_SEBTE/10-162      AC D1AI70.1
#=GS Q7N919_PHOLL/6-167       AC Q7N919.1
#=GS W5TEN4_9NOCA/13-158      AC W5TEN4.1
#=GS H7F7U8_9LIST/5-171       AC H7F7U8.1
#=GS Q8RIJ3_FUSNN/5-162       AC Q8RIJ3.1
#=GS A0A0F2JD47_9FIRM/33-190  AC A0A0F2JD47.1
#=GS Q0WE35_YERPE/6-162       AC Q0WE35.1
#=GS F5LCL1_9BACL/10-163      AC F5LCL1.1
#=GS F7NK27_9FIRM/6-166       AC F7NK27.1
#=GS W0PF08_9BURK/8-164       AC W0PF08.1
#=GS A8FA37_BACP2/5-154       AC A8FA37.1
#=GS A4XSI4_PSEMY/1-122       AC A4XSI4.1
#=GS G4CP07_9NEIS/2-158       AC G4CP07.1
#=GS R5CVV2_9FIRM/5-164       AC R5CVV2.1
#=GS A0A0M9WT42_9BACI/5-154   AC A0A0M9WT42.1
#=GS Q5F606_NEIG1/3-154       AC Q5F606.1
#=GS A0A077LG46_9PSED/8-169   AC A0A077LG46.1
#=GS R6N1I8_9CLOT/6-163       AC R6N1I8.1
#=GS E3H5E8_ROTDC/12-171      AC E3H5E8.1
#=GS F7NGF5_9FIRM/10-162      AC F7NGF5.1
K8VZG2_9ENTR/32-129                 ....................ss---IYSIASLSWCDIKWGYE.........YKFISRDIPIKKAEESV..LTNA.-YTTNELELS...F.LTLD.G-S...DVTSFLEELCPA......CKQEDES.TIKEN..........------..----.-..------...........-.-------------------------------..---.-----------------------gcllflvgcvnkikifre....
A0A068Z3H6_9ENTR/8-164              .....................f-DFIEKNIDLSWCDVRWGYE.........NNLITSELPIRKAERKV..LTGS.-YSVPELELS...F.VIPD.SSD...HIDHFLKEICSG......FEKENDA.TVKNK..........WLFIVL..SWLW.N..NRDHFE...........D.PLNEVEIIYSDFNYPSEIEGFVKYMPPSDEY..DSS.VHTQMENINHLMDNWKEYLEKES......................
R5L882_9FIRM/27-178                 ..................tyal-----RLVQINWADIMFAIE.........NDYFDIEAAVEYAVHLM..ELDQ.-SDDLIIELAcikA.NELI.REE...IIENYINKFVER......TTVEERQ.EAKDK..........ILYAVM..NYLY.E..NKQIFE...........N.PATVIEVVYDDFGFPESMKKVVSYIPSKNEL..---.----DKENNLFYNNWSEYLLQ--qr....................
D8PDY7_9BACT/6-79                   rwnlkelldkpcpsshclqrly--------------------.........-----------------..----.----------...-.----.---...------------......-------.-----..........------..----.-..------...........-.-----SELYSDFGCPHEIARFVRYMPLEDEY..DPR.KHSKVENEGHMLEQWRDYLIE--ae....................
A0A0G0MFB4_9BACT/11-169             ....................qk--LQAIGFKINWTLLKIGYEgq....dflPKLISSNAISQYTECLV..ETME.SDYELIVQL-...-.ISPE.DEM...EFCEILEKLARD......-ENVEQS.IQQRK..........LRVYVV.lEALE.T..LPNDYF...........N.GLLELTDTWVSLGLPDDCPHV--VQGRNNTY..TPQ.EYYTQDVFNSLLEKNKQWVRDE-i.....................
Q5YQU5_NOCFA/15-157                 ..............asfivdwa--------RLTPRELHYGYT.........NQWISSADVVELALGSI..VPSG.SKMGIVEEIS...L.LLSD.ELD...RIPELMDQLIDR......-------.-DDRV..........WTYLAL..AWVH.E..NQEEFD...........D.PFKTVDLIFADFGYPQDVGEFVTFMPPPPG-..---.---GVPGYPGLRQRWKDYLE---qnr...................
I8AF88_9BACI/4-155                  .....................k-DLKNRNIEYDWKTIFVGVQ.........ENYFSKDVISDYAVELM..KRYD.-ESGMVNELAw.gV.CSEDlNRV...LLEIKTNYFPQS......DEYCEILvYENRK..........LRFVYL..SVLK.E..ECKEGH...........E.LLNKIAEFYGNHHYPEEMLSFINYMPSEVP-..---.-----------------------stkedllyrfdeflkier....
Q97M49_CLOAB/6-167                  .....................d-MLDKSGIDYDWRTLYVGIS.........INLVKCDELTTYALKMMndDKYE.-DDEFINELAwgiE.DNLK.GEI...LTKMLFKFKIDMl....vPQSASWE.LEIRK..........LRYGIL..NYLR.S..TIKDDN...........E.LLRKVEEVYADFNYPQDMEQFIAYMPAKNN-..-SV.THSIEDNNKRMINNLDKFLIVEK......................
K8EM63_CARML/4-155                  .....................k-NVKLTNIRYNWSTIYVGIE.........EGYFDETVLTDYAIELM..EKGE.-DSDFINELAwgiS.KDEL.PEV...MLNIKISYLPEI.....dETKFEWS.FENEK..........LRYVYL..SNLK.N..ESKDNQ...........E.LLNGITQFYDNHNYPEDMIPFINYMPQDSP-..---.-----SNENDMLKKFNEFLKIEK......................
A0A0B4RBL2_9BACL/18-183             .....................l-SFIEELVLLNWEELYMGIK.........WNYVSPEAAIEKAIKYL..DFND.--SEDIIGLA...S.LYSN.EIS...SVNYYLTKILSN......NKSTDIK.EIQEK..........WLYLVI..SWLR.K..NHANYNiiyaevnypikE.LFEKISVVWDDFKHPESLGKIFYNQEVFDNQ..D-F.QITEANNTEDFNVFLNNYLS---eqs...................
Q880F1_PSESM/8-164                  .....................d-LFIYDCVFLCWRDTLWGYE.........RGLVGWDFVVGLANFSV..SKGA.-SHPWELELI...F.LGEF.EVQ...EVEKKLRSLAEQ......EDERLGL.DSQKK..........WLFIAL..KWLF.E..NKNNID...........D.PLGVVELIYEDFGFPFEIEGFVRYMPSQDGY..KPE.ENTSQQNIERIFCNWQSYLKRM-a.....................
C7M529_CAPOD/2-162                  .....................v-LFDKGFILNDWRVVYVGLK.........KHWFTPEEVLSYCEY--..GYIL.CSEEMFTEMY...M.LSEF.SDE...NLLNLTRKIYPDp....iWKKIDDN.LYERQievsknyylfWAVEKL..LEIV.A..LGKDKT...........S.KLYEVDMIHSEFDWPIEWHNFIYYMPPKKG-..---.---EKMGIDVLYDDLIEYIDNS-t.....................
Q1D2F2_MYXXD/2-148                  ....................rt--------RLTWREVLFGVD.........NELLSSEVPVEMAVEQL..GIED.WPVRALAELA...D.L--E.PWK...SPRSCVEALAGT......EASQDAE.AIKSK..........WLYLVL..AWVF.I..NREHFS...........D.PLEMGEKIYADFGYPERVARFIRYMPSDE--..-PD.LGSREMNERRLYSQWKSYLDE--ls....................
A0A0B1YBY4_9BACI/10-160             ......................YKFVSDFVKVTWDFVLYGIE.........KSFFNNDFAIEYAISEV..GKSN.DSRPQVFEIA...S.--LF.TGE...SINPYIEELVDR......-VDINED.ELKEK..........LLYVLL..EWIF.D..NKEQFP...........N.SLEMVERIYADFDYPVVISKIIGYMPPPLN-..---.ENESNFGEEYLLTKWKEYLDEQ-q.....................
Q7DDS4_NEIMB/3-154                  ....................ld--LTAQKVRLSWKDILWGYG.........NKYLGWADVAAYARKMT..LS-D.-HDERVFKLS...L.INKS.NIL...ELKPVLEDLASE......MRD----.YSPKN..........WLYVLL..SDVF.H..RKEEFE...........D.PLGEVEKIYADFDYPEEIESFVRYMPPKDGY..IPS.AHTYEENIARLYSHWEHYLNN--gg....................
R5NN53_9FIRM/9-150                  ...............eelntli-------SDWKWSELKYGLC.........REYISIKDVISYANEIL..SNDV.PYMEIIIQLL...I.---A.DDE...EVDDILEKLVSC......EESPSED.NIKSK..........WIFAFI..YHAF.T..YSKD--...........K.IFDIIEDVYEEFDYTEEISNLVPYMPCEDSL..---.-----------------------pledrlkryieqnrn.......
D8MSB5_ERWBE/8-164                  .....................f-DFIDKSAHLSWCDVKWGYE.........NNLITSDVPIKKAEKNV..LTGG.-YTNPELELS...F.VIPG.EVN...QMAPFLKKLCSE......FEQKDDL.TTKKK..........WLFIVL..SWLW.S..NRNSFE...........D.PLAEVEIIYADFDYPSEMEGFIKYMPPSDGY..DPS.THSQMENINHLMGKWKNYLEKG-s.....................
A0A0A8JMK0_BACSX/5-168              .....................d-IFKQSQISYDWKTVYAGIK.........LDLLKPSEITSYAVELV.tRRSE.INDQNFIQLA...WgEDPD.NEI...VLIRLLEELGVQd...ldLDADIWQ.IEKRK..........WRFALL..ASLKmK..YPDDLK...........E.LLNQVAEVYADFDYPEDMESFINYLPPPKGF..DHS.RYTKEENIVRLITSFNEFLTKE-q.....................
D1AI70_SEBTE/10-162                 ......................YSYIYNLFPITWGDILFGIH.........EGFLDFKAAVEHSYNII..EKEE.NSSQRVLDMA...F.LHGN.E--...SIYPLIDELVEE......ENKYDEK.HAKEK..........YLYAVL..KWVY.K..NQSTFL...........E.PLEAVECIYADFGYPEIISKFVRYASNNE--..-PD.LGSRELNIKRIYNNWEKYLETEK......................
Q7N919_PHOLL/6-167                  ......................YLLAKKMELLDWGMIFLGAKg......npVGRLSAPNISEFACNEL..TKLD.LSDSILVEVSeaaF.CTEI.NRE...VIDSL--EVICD......KKNINIQ.LSERK..........WRYVALyiLLLN.E..LPDDYV...........Y.GLLKLNEFWNLWGDSVDSPNI--VQGVGNNL..SPT.EYYSEENYHLLIEKHRNWLDREI......................
W5TEN4_9NOCA/13-158                 ..........sfigsrarltpg-------------ELQYGYR.........NDWLSAEDVVRIATEYV..VPET.DSLKAVEALS...L.LLSD.ELD...RVPELVEQLTAD......VE-----.---SV..........WTYLAV..AWVY.E..HPADFD...........DnPIQAVEMLYADFGCPAEMEPFVPFMPPPPGG..---.-----------------------kpgpeglderlrsylteswdrf
H7F7U8_9LIST/5-171                  .....................d-EFKKNDIPFSWRELKIGRWgysdkefylQSILDDEFVMKYTLDYL..SKNEkEENSYVWELG..sL.FSPY.DEN...EIYRLLNLIAIS......--NEKDL.TSYYR..........WRWILV..NNLL.QkiLDKDYV...........N.ALLEVSEFWLDLKSPIDMPYQ--YQGVENKL..TPQ.EFYTKEHLCKVISDHKKWLEVEK......................
Q8RIJ3_FUSNN/5-162                  ......................EDFKNNNLKINWKIIDIGCLgs....kifRNELSYDDIINFSL---..EKFD.EKNKIILKII...S.SDKD.EYE...EIGILVRELANI......-EKSEYE.IAFEK..........WELVYI.kKNLP.V..LNKNFI...........Q.GLIELNDLWFRLDFPEDSPYI--FQGVKNNI..SPQ.EYYTEENYIYLYNRHLNWIRDK-s.....................
A0A0F2JD47_9FIRM/33-190             ...................yvy---VTNLVPLNWNDILFAIE.........NNFLAHQTAIEHGLEAV..QKNE.NVPEEVLELA...F.MLQG.EAKlpyDVYQLVNKLATS......HNPDNAS.DSREK..........FLYVSL..NWVY.E..HKDDYC...........N.PIEVVDILCDEINYPDEVKNLISFMPTSES-..--E.TNSSDSTTERLLGRLLRYLENQ-r.....................
Q0WE35_YERPE/6-162                  ......................YEFICSHIKLSWFDIKWAYE.........KKLIGWHSIVKHAEHLV..SLGE.-ASQLELELS...F.KSKM.DTH...EISLILDDLSMC......CIDADES.ATQEK..........WLFIIL..LWLF.T..NRNNYS...........E.PLKMVETIYEDFDYPEAIESFVAYMPVSDGY..DPN.AHSHRENTERLFRNWQTYLDQES......................
F5LCL1_9BACL/10-163                 ......................YDYVTNLINLTWSDLLFAVE.........QGYMSREAAVEHAINIV.gKEKE.KTHQKVLELA...C.L-TN.EES...NFWYI-DELLNQ......IYEQDGS.SSRDK..........FLFLLL..NWIF.E..HKELYL...........D.PLEMVENIYADFNYPEKISEFVRYMPSKRTI..---.TSLVKLNTAYLYNRWKEFLEQE-r.....................
F7NK27_9FIRM/6-166                  ....................el--MQSTKLKVNWTTILVGWKgf....gkfSRQFSSKDVIDYAVEVA..SNDD.KQPEETWELA...G.LNNS.ESE...NITGLLERLSQK......-EEHKEQ.DEFRK..........WRAILT.kQLLT.K..LPNDYL...........E.GLIAITDFWDKFQFPDDSPHI--VQGRNNEI..SPT.EYYSQENYLKLIEAHKRWVDDEI......................
W0PF08_9BURK/8-164                  ......................YDFINKIIELSWCDIRWGYE.........REIITLDIPINEAERRV..LSGS.-YTDRELELS...F.VIPG.QSD...EVISLLKLLCSE......CEMDDES.TAKQK..........WLFIVL..RWLW.E..NRHSFN...........D.PLNEIAGIYADFSYPAEIEGFVNYMPPSDGY..DPV.IHTETENINRLMDNWRYYLERT-s.....................
A8FA37_BACP2/5-154                  .....................e-IITKNGFDCNWSTLFIGRQ.........FNLISALEVTNYAVKYL.eNNPN.ANNELMLELA...W.--EQ.EEV...KVDNILESITSD......SSSEDMK.REYHK..........WLYSTV..KETY.S..HSSD-E...........D.IFEEIENIFSIFNTPENMYDF--FRKVSDA-..---.FYYPHDSKNTIKELVEEFLETEK......................
A4XSI4_PSEMY/1-122                  ....................mn--------------------.........NGWINKDAVSEHAFRLL..SAGQ.-QDSDISVLA...G.SDAL.SDD...EVVVLLATLCKKe...giDLQEKRS.HALEK..........WRLAML..SELQ.H..SSLADE...........D.KIERLQELYAEFGYPDDMASCSIYA------..---.-----------------------qndvdpidalhq..........
G4CP07_9NEIS/2-158                  ....................dy--LTNDLIGLSWDDIKFGYH.........NQYLGWHDIVNFAKANL..KNFP.-ENDLIDELA...F.LTKC.NAF...KVGIILERLSPN......FNY--DD.YDKGK..........WLYIIL..KKVY.E..SKDSFD...........D.PLEEVEKIYADFDYPEEIESFVRYMSIHDNGgdEFL.LQSKEDYIQRIYNNWAKYLEDK-q.....................
R5CVV2_9FIRM/5-164                  ......................YLIKKIGFKVTWKLISVGLYgn....reiPVLISRKDITLFLDELL..MNNN.ACADDIIAL-...L.CEEN.YPT...DFDVLLHKYASI......-DKSELP.IQNRK..........WKACLL.mEVLD.A..ISEDHL...........Q.GILELIEFWVSMNVPNDCPQK--FPIPNNKE..SIN.EYFSQESFQKLVDENRIWLEKEI......................
A0A0M9WT42_9BACI/5-154              .....................e-IIKKNGFNCNWTTLFIGRQ.........FKLISSLEVTNYAVEYL.eNNPN.VNNGFILELA...W.--EQ.VED...KVDDLLEKIISD......SSPEGMT.KEYHK..........WLYSII..KEVY.N..NSSA-E...........N.VFQEIENIFFMFNTPQNMYDF--FRKVSDA-..---.FYYPSDSKHTIKELIEEFLNAEK......................
Q5F606_NEIG1/3-154                  ....................ld--LTAQKVRLSWKDILWGYE.........NKYLGWADVAAYARKMT..LS-D.-HDERVFKLS...L.TNKS.NIL...ELKPVLEDLASE......TR----G.YSPKN..........WLYILL..NDVF.H..RKEEFY...........G.PLGEVEKIYADFDYPEEIESFVRYMPPKDGY..IPS.AHTYEENIARLYSHWEHYLNN--gg....................
A0A077LG46_9PSED/8-169              ..................riar------HALTDWGVLLQGVYgi....pglLGKLPTSYVENYANAEL..EQVA.-GDSPLLDVI..vS.LAND.SDL...SLSELCPQLQKIc....dFQNVDMQ.RASRI..........WRAAAL.eKLLA.N..LDTEPL...........Y.GLINLSEFWSIWEWPADAPLS---MIPGKMT..LPEhKYHSDSNYEHVIHEHAQWLKEE-l.....................
R6N1I8_9CLOT/6-163                  ......................YSIKKLGFSIDWTLIEIGLYgk....afiKPQITKSEVIQYCYTLL..EHKT.TYEKTVVEL-...I.CEKD.NDA...NFKKLVSKLISY......DKTVDID.ICLRK..........WRAFIL.wNLLS.H..LTSDYM...........Q.NLLEINEFWAEMGFPENVDHI--YPSSKN--..-IS.IYFTSVNCNRIIKKNTHWLHNEI......................
E3H5E8_ROTDC/12-171                 .................girks--------ALTWQGLRWGLA.........QGYISRADILRYASDRL..KE-D.-SSDLEYELY...Q.CKPD.HTY...RVDGILAELARHegppelT------.--NPDpgstdprhalWLYLLL..KHVY.E..HRKNFD...........D.PLGEVEILHADFGYPEDVTPFVRYMPPTD-Y..DPS.TYTHQENIDRLYALWEAYLRE--ak....................
F7NGF5_9FIRM/10-162                 ......................YDFVSKRVQLTWKDILYAIN.........RKLLPSDSAIEHATVKV..SQGE.EYNQTLLDLA...S.LYKG.E--...SVQPYLDELARL......DSGQDDT.ILNEK..........WLYLVL..DWVF.E..NKDNYA...........D.PLGIVEQIYADFDYPEVIASFVRYMPSDE--..-PP.LGTLELNEARLYEKWKDYLDI--qr....................
#=GC seq_cons                       ........................hhtphhplsWpslhhGhp.........pshlstcsllpaAhchl..ppts..psphlhELu...h.htts.ptp...plp.llccLssp.......pp.p.p.htpcK..........WhallL..phlh.p..pppsat...........c.sLtplpplau-FsaPc-htpFl.YMPspss........h.pppshpclhppappaLcpt.......................
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