GenomeNet

Database: Pfam
Entry: DUF2353
LinkDB: DUF2353
Original site: DUF2353 
#=GF ID   DUF2353
#=GF AC   PF09789.4
#=GF DE   Uncharacterized coiled-coil protein (DUF2353)
#=GF AU   KOGs, Finn RD, Sammut SJ
#=GF SE   KOGs (KOG4687)
#=GF GA   30.00 30.00;
#=GF TC   30.00 30.90;
#=GF NC   29.50 28.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019179;
#=GF CC   Members of this family of uncharacterised proteins have no known
#=GF CC   function.
#=GF SQ   117
#=GS G3N1V2_BOVIN/21-333   AC G3N1V2.1
#=GS H0ZGL9_TAEGU/1-250    AC H0ZGL9.1
#=GS B4QYH7_DROSI/16-88    AC B4QYH7.1
#=GS A7S0L0_NEMVE/21-369   AC A7S0L0.1
#=GS B7PEV1_IXOSC/23-211   AC B7PEV1.1
#=GS G1PQP0_MYOLU/25-337   AC G1PQP0.1
#=GS G3Q129_GASAC/1-268    AC G3Q129.1
#=GS F7HGU1_CALJA/1-221    AC F7HGU1.1
#=GS F6VHN9_CALJA/1-267    AC F6VHN9.1
#=GS F4WMZ8_ACREC/25-236   AC F4WMZ8.1
#=GS B5DTM9_DROPS/369-690  AC B5DTM9.1
#=GS F1LVF5_RAT/1-251      AC F1LVF5.1
#=GS F7EPZ1_MACMU/3-265    AC F7EPZ1.1
#=GS G3ID80_CRIGR/19-210   AC G3ID80.1
#=GS F1L8B8_ASCSU/36-367   AC F1L8B8.1
#=GS H0WWN3_OTOGA/1-263    AC H0WWN3.1
#=GS B7PEV1_IXOSC/208-285  AC B7PEV1.1
#=GS H3D498_TETNG/1-284    AC H3D498.1
#=GS H9JPM0_BOMMO/27-348   AC H9JPM0.1
#=GS C9JIN5_HUMAN/3-262    AC C9JIN5.2
#=GS B4K9Q5_DROMO/44-363   AC B4K9Q5.1
#=GS B4NTC3_DROSI/21-277   AC B4NTC3.1
#=GS C3Y474_BRAFL/1-309    AC C3Y474.1
#=GS A8MPT5_HUMAN/2-263    AC A8MPT5.1
#=GS F1N882_CHICK/3-263    AC F1N882.1
#=GS Q9VF72_DROME/27-345   AC Q9VF72.1
#=GS CC149_BOVIN/1-283     AC Q0VCP9.1
#=GS F7E6W7_CALJA/4-263    AC F7E6W7.1
#=GS Q5DCC2_SCHJA/21-163   AC Q5DCC2.1
#=GS B0WKT3_CULQU/252-315  AC B0WKT3.1
#=GS F6WD34_ORNAN/1-268    AC F6WD34.1
#=GS E3M227_CAERE/20-337   AC E3M227.1
#=GS H2SZ48_TAKRU/1-190    AC H2SZ48.1
#=GS B4G3T5_DROPE/202-523  AC B4G3T5.1
#=GS B4JER0_DROGR/51-370   AC B4JER0.1
#=GS B8JKE4_DANRE/1-284    AC B8JKE4.1
#=GS G1NIM7_MELGA/3-281    AC G1NIM7.2
#=GS H9G1M4_MACMU/26-338   AC H9G1M4.1
#=GS G6CPW1_DANPL/26-330   AC G6CPW1.1
#=GS H3EQH8_PRIPA/13-235   AC H3EQH8.1
#=GS H0VDE0_CAVPO/25-337   AC H0VDE0.1
#=GS Q5DC08_SCHJA/1-108    AC Q5DC08.1
#=GS B0WKT3_CULQU/25-256   AC B0WKT3.1
#=GS E1C1B1_CHICK/1-83     AC E1C1B1.1
#=GS E1C1B0_CHICK/1-219    AC E1C1B0.1
#=GS G5E6X6_LOXAF/1-282    AC G5E6X6.1
#=GS G4LXA7_SCHMA/21-264   AC G4LXA7.1
#=GS H2MYS7_ORYLA/1-122    AC H2MYS7.1
#=GS F7C6Z6_MONDO/1-283    AC F7C6Z6.1
#=GS B3SAY2_TRIAD/72-401   AC B3SAY2.1
#=GS H2QPA5_PANTR/26-338   AC H2QPA5.1
#=GS F7E6T9_CALJA/3-262    AC F7E6T9.1
#=GS G1K8G7_ANOCA/1-215    AC G1K8G7.1
#=GS A8XQT7_CAEBR/19-335   AC A8XQT7.2
#=GS CC149_HUMAN/1-283     AC Q6ZUS6.2
#=GS B5DXD0_DROPS/368-689  AC B5DXD0.1
#=GS H2VWG9_CAEJA/20-336   AC H2VWG9.1
#=GS G0M6S4_CAEBE/20-336   AC G0M6S4.1
#=GS H2YNP2_CIOSA/2-160    AC H2YNP2.1
#=GS G1S4E8_NOMLE/32-343   AC G1S4E8.1
#=GS H2XNP3_CIOIN/22-325   AC H2XNP3.1
#=GS H2UFK8_TAKRU/1-289    AC H2UFK8.1
#=GS F6QT63_XENTR/1-283    AC F6QT63.1
#=GS Q1DGS4_AEDAE/27-281   AC Q1DGS4.1
#=GS G1LPB2_AILME/26-338   AC G1LPB2.1
#=GS Q7PTQ8_ANOGA/37-361   AC Q7PTQ8.4
#=GS H3A7B3_LATCH/6-318    AC H3A7B3.1
#=GS G3Q7L3_GASAC/1-267    AC G3Q7L3.1
#=GS G3W7F9_SARHA/15-318   AC G3W7F9.1
#=GS G4LXA6_SCHMA/2-209    AC G4LXA6.1
#=GS E9JD86_SOLIN/1-310    AC E9JD86.1
#=GS F7HVV9_CALJA/6-318    AC F7HVV9.1
#=GS C149B_DANRE/1-284     AC Q6DH86.1
#=GS B4PS33_DROYA/27-345   AC B4PS33.1
#=GS B4HM16_DROSE/27-154   AC B4HM16.1
#=GS I1GEI8_AMPQE/29-318   AC I1GEI8.1
#=GS O18529_RHYAM/22-280   AC O18529.1
#=GS G7Y3A9_CLOSI/5-188    AC G7Y3A9.1
#=GS F1QC51_DANRE/1-283    AC F1QC51.1
#=GS E2C5S8_HARSA/25-331   AC E2C5S8.1
#=GS H2YNP1_CIOSA/22-204   AC H2YNP1.1
#=GS D6RDA1_HUMAN/26-229   AC D6RDA1.1
#=GS H9IG47_ATTCE/25-313   AC H9IG47.1
#=GS Q93635_CAEEL/20-336   AC Q93635.1
#=GS F1PAT3_CANFA/1-256    AC F1PAT3.1
#=GS G3ID80_CRIGR/202-295  AC G3ID80.1
#=GS E0W0A1_PEDHC/26-335   AC E0W0A1.1
#=GS I0FW89_MACMU/26-338   AC I0FW89.1
#=GS B4NA37_DROWI/36-356   AC B4NA37.1
#=GS E5SCH7_TRISP/1-181    AC E5SCH7.1
#=GS Q4S6J5_TETNG/22-335   AC Q4S6J5.1
#=GS F4HID0_PYRSN/104-248  AC F4HID0.1
#=GS D2I2A4_AILME/8-321    AC D2I2A4.1
#=GS C149A_DANRE/1-283     AC Q5XJA2.1
#=GS F4WMZ9_ACREC/29-332   AC F4WMZ9.1
#=GS H2PD14_PONAB/6-318    AC H2PD14.1
#=GS E7FE63_DANRE/22-334   AC E7FE63.1
#=GS F7B7V3_HORSE/1-282    AC F7B7V3.1
#=GS F6WD54_ORNAN/5-262    AC F6WD54.1
#=GS H3JFA4_STRPU/20-317   AC H3JFA4.1
#=GS G3R3U2_GORGO/26-338   AC G3R3U2.1
#=GS G1ST40_RABIT/1-286    AC G1ST40.1
#=GS Q16UI1_AEDAE/24-343   AC Q16UI1.1
#=GS E3WMC5_ANODA/81-335   AC E3WMC5.1
#=GS H2LJ92_ORYLA/1-267    AC H2LJ92.1
#=GS CC149_XENLA/1-283     AC Q6NRH3.1
#=GS G5B026_HETGA/41-100   AC G5B026.1
#=GS G8F4U0_MACFA/1-283    AC G8F4U0.1
#=GS G1U7G1_RABIT/6-267    AC G1U7G1.1
#=GS G3W7F8_SARHA/26-341   AC G3W7F8.1
#=GS B3LZR9_DROAN/27-345   AC B3LZR9.1
#=GS F6URH4_MONDO/1-251    AC F6URH4.1
#=GS B3P0W5_DROER/27-345   AC B3P0W5.1
#=GS E2A489_CAMFO/24-330   AC E2A489.1
#=GS B4M6H0_DROVI/50-369   AC B4M6H0.1
#=GS F6SES1_MACMU/1-283    AC F6SES1.1
#=GS E7F2N0_DANRE/22-335   AC E7F2N0.1
G3N1V2_BOVIN/21-333              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQN..........................KSS---SSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
H0ZGL9_TAEGU/1-250               ..........................a-------------------------------.---------------------..-------------.............................---NLAQLLSEAQDRNKHLGEEIGELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..D.EV.G.AR..HFA...................aHEREDLVQQL......EKAREQIETLRYDLQAALDELQDVKEERSVYQDKSDRL...NQEL...NHVL......GGHEN............RII.DIDALCMENR...YLQERLKQLQEEVNLLKSSITKYKN.ALERrK...NS..KTHS..........................RSS---SSALTGV.LSAKQV.....QELL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B4QYH7_DROSI/16-88               ...........matynveppasetile-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....----------SgiDLPQKTESLSDLKSLCLGLLDNLNDKNLALTHQKKTNK.ILAGKMTELEQRWQQL...................
A7S0L0_NEMVE/21-369              ...........................KKKLESKRQALKILMGDLESCQRERDIYKNK.IKQLQQEVDNYKKQEREREMK..ALRGGRSPMSPRSpehhkslkrerrlsgnsiweqelqnvrdrKNKTLSQLLCESREENKALVNDFNDLRGLYKEAQEDIL.....LLRENLARQ..RSSF..K.GQ.G.TS..EDL....................EARQNLIKEL......EKSREKEQQLERDLQAVHDEKGEVAVERDHYREKSNRL...NTQL...NFIL......GADEQ............RLV.DIDAVLMENR...YQREHIKQLKEEKSMASAALNRYKA.AFE-.K...KK..NRLL..........................QAGYGQPGNHTGV.HGAKQV.....FPAILSELTHSfgGGGVSTNTASELQFLANSLSESLSEKDIALLHQKNTNR.ILGNRVAELEKKLKTL...................
B7PEV1_IXOSC/23-211              .........................rc--RLESKGEALLILTRDLEQCQSERDQYKLM.ADQLRERHAELKRRVQGWGPT..IAGVYDVRNLKGQ.............................AEKSLAQLLCEMKEQNRALQTELTDVRQKLQEAREDGK.....LLREQLRDR..QSLA..A.GE.EePC..LGP....................GDRIALVTQL......EAVRSKCQLLERDLQAVLDEKEELVRSSDAYRHKVDRL...NLQL...NLSL......AE---............---.----------...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------knrgr..............
G1PQP0_MYOLU/25-337              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLVQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALE-.R...RK..NTK-..........................GQGRSSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G3Q129_GASAC/1-268               ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rNQVNLAQLLRDSREKSCQLSDEVKELKQRLVEAQGDNK.....LLRMTITKQ..RLGD..E.EV.G.TR..HFP...................aHEREDLVKQL......ERAGEQNEVLEQSAKSLTDELQDVRAERDVFQQKAHRL...NVEM...NHIL......GNDEI............RML.DVDALCMENR...YLHERFCQLQEEVSLLKANLVKYKS.ALDC.R...KT..SKFC.........................gKPN---SSALTGV.LSAKQV.....KELLLSEENSC..SLPVTPQSISDLKSLATALLETIHEKNMVIQHQRQINK.----------------...................
F7HGU1_CALJA/1-221               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENRqyvYLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQ-.....-----------..--------------------------------------.----------------...................
F6VHN9_CALJA/1-267               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.----------------...................
F4WMZ8_ACREC/25-236              ...........................KRKLQMKSEALMLLSKEMDQSRIERDQFKLM.AEQIQERFLHLKKQMCDMK--..--ELN----SFDD.............................DFRT-LDLLTEAREQNKCLRLQVETLRQKLTDAEGDIK.....VLRTNNNRI..PIEQ..Q.ET.Q.LA..PAM....................HQREEMIEQL......EKLNLKCSQLQTDLQTVLDEKHELKIERDAFKCKAHRL...NHEL...SKAL......NA--T............KPV.DLDALINENR...YLQERLQQLLEEKELTRQSLSKYK-.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------...................
B5DTM9_DROPS/369-690             ...........................HRKLQSKVEALRILRLELEQFRVERDQYKLM.AETLQLRYSALKHNS---ELV..TVGGN--GCGPLS.............................QNSSLAALLHETREQNLKLNTEVEGLKQRLNEIQGDME.....LLRETEASN..KARV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......ENLKKKNAQLAFDFKAIIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pKLL.DIDGVLLENK...YLHERVKIQEGELDLTKQSISKYKS.MLDA.K...RK..KGIV..........................KLGGGTSTNDETI.LSPRQV.....KTILESGI---..DLPQKTETIHDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAGKMTDLEQRWQQL...................
F1LVF5_RAT/1-251                 ..........................q-------------------------------.---------------------..-------------.............................--ANLAQLLRESQDRNKHLGEEIKELRQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVEQL......ERAKEQIESLEHDLQASVDELQDVKEERASYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVSLLKSNIAKYKN.ALERrK...NS..KTQG..........................KSN---SSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSIADLKSLATALLETIHEKNMVIQHQRQTNR.ILGNRVAELEKKLRTL...................
F7EPZ1_MACMU/3-265               .....................ihhfll-------------------------------.---------------------..-----------KR.............................KQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENRqyvYLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G3ID80_CRIGR/19-210              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..-------------.............................--ANLAQLLRDSQDRNKHLGEEIKELRQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.MR..HFA...................aHEREDLVEQL......ERAKEQIESLEHDLQASVDELQDVKEERASYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------rnalerrkn..........
F1L8B8_ASCSU/36-367              ...........................KKKCASKSEAILSLSQQLTSSQEQMNRYKKA.AECFEKRMQQAEQSCKAVMQE..YASFE---IESIK.............................EKETLTKENERLRQDVQRLVAENSSYKAEVKDIRSECK.....ALRQKLARF..EVEKyrK.NE.A.AS..EQIpnattaes....fhedgvtsRRGSMLLETF......EKINAQNSHLQRDVQSLLCEKEELVCDRDALKCKVQRL...SQEL...SYLL......NGDPN............RIVdDIDGVLAENR...YLKARLENAQEETGLTRAALKKYRR.MVKG.KivgRS..NSIEee......................pyL-ANG-ERTTFGA.YTAEQI.....SRVLGSKSLEL..-------NDGDYRSLSAALLESCSDKLIALTHQRNANK.ILGRRVTELEAQL---vq.................
H0WWN3_OTOGA/1-263               ...........................-------------------------------.---------------------..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B7PEV1_IXOSC/208-285             .................nrgrggaagi-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................----------ATG.ISNKQM.....QQLLQGCSTD-..---VSSA-TADVRSLVALLLESLNDRTLALNHQRKANK.VLGKRITELESRLKA-...................
H3D498_TETNG/1-284               ...........................------------------------------M.ANQLRERHQGLKKKYSELM--..---DGDPSLPPEK............................rKQVNLAQLLRDCRDKNSQLSEEVKELKQRLLEVQGDNK.....LLRMTITKQ..RVGD..E.EV.G.AR..HFP...................aHEREDLVQQL......ERAREQSEILEHSVKSLTDELQDVCAERDVFQQKAHRL...NVEM...NHLV......GNEDT............RVL.DVDALCMENR...YLHQQFNRLQEEVILLKSNIVKYKS.ALECrK...NS..KTFM..........................KPN---SSALTGV.LSTKQV.....KELLQSEENGC..SLPVTPQSISDLKSLATALLETIHEKNMVIQHQRQINK.ILGNRVAELEKKFQTL...................
H9JPM0_BOMMO/27-348              ...........................KSKLQSKVDALCIMSKELDKCSMERDKYKVL.VEHLK-SKKVVSSKIAENN-N..AY-----RFTPTN.............................T-ISNGDMFAQTKDHNNMLKVEVEMLRSKLEEAAGDIL.....VLRKQLQNT..RPCKgyD.NK.D.IC..NDTty................taVDYERLVNDL......EKMKKKYQQIQLDYRATLDEKEELVSDRDYYKNKVQRL...NHQI...SYLL......SNRSNlptgegesaapsPIV.DIEALIAENK...YLHERITQLQIENELIKRNLSKYKT.LLDN.R...SR..NYSV..........................HLK----KGFADV.MTQKQV.....KEFLENNLKS-..--NSKHNSAAELKSVCLGLFEALNDKSTALQHQRKTNQ.ILASRLTELEKTLEA-w..................
C9JIN5_HUMAN/3-262               .....................ihhfll-------------------------------.---------------------..-----------KR.............................KQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.AI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B4K9Q5_DROMO/44-363              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLM.AETLQLRYSAMKRNSELLA--..--GNG-NACGALS.............................QNSSLAALLHETRELNLKLNTEVEALKQRLNELQGDME.....LLRERECNS..KSRL..Q.TL.L.NE..NAAhnke...........elqwkRERANFICHL......ENLKKKNAQLAYDLKGIIDEKEELITERDAYKCKAHRL...NHEL...LVAL......KANKMh..........pKLL.DIDGVLLENK...YLHERVKIQESELELTKQSVNKYKN.MVEA.K...RK..KGIV..........................KLG--GSANDETI.LSPRQV.....KTILESGI---..DLPGKTETIHDLKSLCLALLDNLNDKNLALTHQKRTNK.ILATKMAELEQRWQQL...................
B4NTC3_DROSI/21-277              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLV.AETLQLRYSALKSNSELLS-V..GGCG------ALS.............................ENSSLATLLHETREQNLKLSTEVEALRQRLNELHGDME.....LLRETEASN..KSRV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......EGLKKRNAQLAFDLKAVIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pRLL.DIDGVLLENK...YLHERVKIQDSELELTKQSINKYKN.MLDA.K...RK..KGIV..........................KLG-GGSTNEDTI.LSPRQ-.....-----------..--------------------------------------.----------------g..................
C3Y474_BRAFL/1-309               ...........................-------------MARELENTQKERDQFKLM.ADQLRERYQTLRKRYEEKERRpkSPTRASDSLDPSQfs.........................dtRSKSLAQLLSEARTQNKRLLAEGKDLTQKLAEAQGDIK.....MLRESLARM..RVGD..E.GV.G.NR..HFP...................kHEREDLVKQL......EEARERTELLERDVQAMSDEKEEMSSERNFHRDRAERL...NEEL...NYIL......RGDEK............RIV.DIDALRMENK...YLQERVKQAQEEKSLLQTTIGKYKQ.ALDR.R...KG..KGIL..........................KIG--ANRTGGVV.VSQKQV.....QQLLHGRMGS-..-IPATPSSVADLQSLAASLVETINDKNMALQHQRNTNK.ILGNRVNELEKKLKTL...................
A8MPT5_HUMAN/2-263               ..................eadlfllrf-------------------------------.---------------------..------------S.............................KNANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.AI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
F1N882_CHICK/3-263               .................tsnyksrdcw-------------------------------.---------------------..-------------.............................-QANLTQLLSEAQDQNKHLGEEIRELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..D.EV.G.AR..HFA...................aHEREDLVQQL......EKAREQIEALNHDLQSALDELQDVKEERSFYQDKSDRL...NQEL...NHVL......GGHEN............RII.DIDALCMENR...YLQERLKQIQEEVNLLKCNITKYKN.ALERrK...NS..KTHS..........................RSS---SSALTGV.LSAKQV.....QELL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
Q9VF72_DROME/27-345              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLV.AETLQLRYSALKSNS-ELL--..AVGGC----GALS.............................ENSSLAALLHETREQNLKLSTEVEALRQRLNELHGDME.....LLRETEASN..KSRV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......EGLKKRNAQLAFDLKAVIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pRLL.DIDGVLLENK...YLHERVKIQDSELELTKQSINKYKT.MLDA.K...RK..KGIV..........................KLG-GGSTNEDTI.LSPRQV.....KTILESGI---..ELPQKTESLSDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAGKMTELEQRWQQL...................
CC149_BOVIN/1-283                ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQN..........................KSS---SSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
F7E6W7_CALJA/4-263               ...................slfllrfn-------------------------------.---------------------..-------------.............................KKANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
Q5DCC2_SCHJA/21-163              ..........................v-QQLDAKTQAVSILNASLEKCRKEKNEFKRM.AEQVMNRYQMLKRTLMEYD-K..GDNYPTSDIM-HL.............................STKQLASLLVESREANKSLEHELMNSREKIEELQGDIR.....VLRKQINDH..SSET..R.YTtE.VK..ISG....................DDRQTYVTQL......EELT----------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------lqvli..............
B0WKT3_CULQU/252-315             ...........................-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....KELLQRGTVE-..ELPLKAATISELKSLCLALLDNVNDKSLALSHQKRTNK.LLAAKISELEQRIQVL...................
F6WD34_ORNAN/1-268               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSIPPEK............................rKQANLVQLLSDSRDRNHHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......EKAREQIESLEHDLQASVDELQDVKDERSSYRDKVDRL...NQEL...HHIL......GGHEN............RII.DVDALCMENR...YRRKRKPLWIGSLRTLKSNLFVYVNsALE-.R...RK..NS-K..........................SQGRSSSSSLTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.----------------...................
E3M227_CAERE/20-337              ...........................QQKCSAKTDTIVRLGQDLEKSETEKKAFAAR.IETLE---RNLERTERELQLV..CSCQNDMKIKFGI.............................EIQDLIEDVNKFKRENQKLKSERQELLDEKADLKKDCK.....TFRQTIAQF..EVEK..M.GG.S.IR..SSF....................STDEDELLRLg...ahEKLQKKCKELESDLRSMLGIKEELLIERDEMQKKVVRL...SNEL...SYLL......NGDPR............RVAeDLDSLVAENR...FLKAKLNTAEEESESIKMTLAKYKQ.MAET.V...NV..QTMMnr......................spKAGDSEEKPSVAV.INMKQI.....RELLASHAIEL..-------DESDYRAITTILLDLCNDKQMALAHSRRANKsVLGMRLHEVESKLAVL...................
H2SZ48_TAKRU/1-190               ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rHQVNLAQLLGNSKEREKKLTEELKELNQSLTEAQGDNK.....LLRMTITRQ..RLGD..E.EL.G.AR..HFP...................aHEREDLVRQL......ERPGLQLEEAEHNVKAVTDELQDVKAERNVFREKACRL...NVEL...NHVL......GNREA............RVI.DVDALCMENR...YLHDRFGQLQEEVDLLKSNILKYK-.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------...................
B4G3T5_DROPE/202-523             ...........................HRKLQSKVEALRILRLELEQFRVERDQYKLM.AETLQLRYSALKHNS---ELV..TVGGN--GCGPLS.............................QNSSLAALLHETREQNLKLNTEVEGLKQRLNEIQGDME.....LLRETEASN..KARV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......ENLKKKNAQLAFDFKAIIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pKLL.DIDGVLLENK...YLHERVKIQEGELDLTKQSISKYKS.MLDA.K...RK..KGIV..........................KLGGGTSANDETI.LSPRQV.....KTILESGI---..DLPQKTETIHDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAGKMTDLEQRWQQL...................
B4JER0_DROGR/51-370              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLM.AETLQLRYSAMKRSSE---LL..AGSGG--ACGALS.............................QNSSLAALLHETRELNLKLSTEVEGLKQRLGELQGDME.....LLREREANS..KSRL..Q.AL.V.SE..NAAhnke...........elqwkRERADFICHL......ENLKKRNTQLAFDLKAIIDEKEELMTERDAYKCKAHRL...NHEL...LVAL......KANKMh..........pKLL.DIDGVLLENK...YLHERVKIQDNELELTKQSVSKYKT.MLEA.K...RK..RGIV..........................KLG-GSTS-DETI.LSPRQV.....KTILESGI---..DLPGKTETIHDLKSLCLALLDNLNDKNLALTHQKRTNK.ILASKMQELERRWQQL...................
B8JKE4_DANRE/1-284               ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rNQVNLAQLLRDSREHNKQLSEELKELKQRLAEVHGDNK.....LLRMTIAKQ..RLGD..E.EV.G.TR..HFP...................aHEREDLVQQL......ERAREQTEALEQSLKAATDELQDVRAERNVYQEKAHRL...NLEI...NHIL......GSHEN............RIL.DIDALCMENR...YLHERLMQLQEEVSLLKSNVMKYKS.ALES.K...KN..CKVY.........................gKSN---SSALTGV.LSAKQV.....QELLLSEENGC..SLPVTSQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELERKLKTL...................
G1NIM7_MELGA/3-281               ........................nne-------------------------------.-------TDKVKKQDRKIK--..--RDNNREMREEK............................eRQANLTQLLSEAQDQNKHLGEEIRELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..D.EV.G.AR..HFA...................aHEREDLVQQL......EKAREQIEALRHDLQSALDELQDVKEERSFYQDKSDRL...NQEL...NHVL......GGHEN............RII.DIDALCMENR...YLQERLKQIQEEVNLLKSNITKYKN.ALERrK...NS..KTHS..........................RSS---SSALTGV.LSAKQV.....QELL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
H9G1M4_MACMU/26-338              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYREMI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G6CPW1_DANPL/26-330              ...........................KSKLQSKIDALSIMSNELDKCCMERDRYKML.VEQLKCK-KHMQH-NNNLD--..--RFA-----P-T.............................NTISGSEILARTKESNNMLKLE--ALLKL-LSLQCEGP.....STRT-VNPL..KAKK..F.HG.H.LK..PTL....................DRKSQALLKLlspatrWTRTRTYRQIQLDYRTTLDEKEELVSDRDYYKNKVQRL...ISQIfnnSAKT......NSENS...........tPFV.DVDTLLTENK...YLHERITQLQVEKEIVKRTLTKYKT.LLDNrN...KS..EPYI..........................KKG------FADV.MTQKQV.....REYLDINS---..KTGLKRGSAQELKRICLGLFEALNDKSIALQHQRKTNQ.ILANRITELEKTLESL...................
H3EQH8_PRIPA/13-235              .....................qarthn------------------------EEDFREM.VDQVQLLQSKLTAKTEALLRV..GETIDRLKSTHAR.............................EKCELEGRIAKAELRLKSTDADGSQLRAEIRELQKDCK.....IYRQKLAKV..EVLR..M.ES.E.DT..GDVfspcasegrrissttrdnrsSIQEQRLEDF......EKLNHEHRQLESDFQTLLTLKEESIQEKDVMAKKIVRL...QTEL...SYLL......NGDTR............RIAeDLDDVLAENR...FLKAQLNSAQEESDSMK--------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------vgri...............
H0VDE0_CAVPO/25-337              ...........................KRKLESKKEALLILSKELDTCQQERDQFKLM.ANQLRERHQSLKKKYRELI--..---DGDPLLPPEK............................rKQANLSQLLRDSQDRNKHLGEEIKELQQRLAEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERASYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKHLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
Q5DC08_SCHJA/1-108               .........................mk-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......------LSELKRELGQCLDEKQEIATERDIYRNKCDRL...NNEL...NYIL......SGDGR............KIQ.DIDTLMAESR...MLKDQIELLQMEKSLALNTVTKYKK.LLDR.K...LS..K---..........................-------------.------.....-----------..--------------------------------------.----------------hsssvssescitpai....
B0WKT3_CULQU/25-256              ...........................HRKLQSKVEALKIMRNELEKYRSERDQFKLM.AETLQMRYSAIKSSLNSAELQ..AAGFG--------.............................HGSAVSLIVNQTRERNLSLTTEVEALRQRVHELEGDIK.....VLRTKNSDL..KTTC..R.KL.K.SS..EQVklnan.........gdilwqEEKSKLIAQM......EGIKKKNAQLQYDFRSLLDEKEEAVMERDAYKCKAHRL...NHEL...SIVL......KGDKSq..........rAIL.DVDGLILENK...HQLEKIANLENELALAKQSAAKYKE.LL--.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------q..................
E1C1B1_CHICK/1-83                ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLTQLLSEAQDQNKHLGEEIRELQQRLGEVQGDNK.....GKQRNKSKQ..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------wvtel..............
E1C1B0_CHICK/1-219               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLTQLLSEAQDQNKHLGEEIRELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..D.EV.G.AR..HFA...................aHEREDLVQQL......EKAREQIEALNHDLQSALDELQDVKEERSFYQDKSDRL...NQEL...NHVL......GGHEN............RII.DIDALCMENR...YLQERLKQIQEEVNLLKCNITKYKN.ALERrK...NS..KTHS..........................RSS---SSALTGV.LSAKQV.....-----------..--------------------------------------.----------------...................
G5E6X6_LOXAF/1-282               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQACVDELQDVKEERASYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................KSN---SSALTGV.LSAKQD.....QDIIQTYANIL..--LATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G4LXA7_SCHMA/21-264              ..........................v-QQLNAKTQAVSILNASLEKCIKEKNEFKRM.AEQVMSRYQVLRKTLMECD-E..ADQYSTPDIMHL-.............................STKQLASLLVESREANKSLEHELMNSREKIEELQGDIK.....VLRKQLSDR..SCEN..QhTM.D.PR..VSG....................NDRQAYVTQL......EELTFQLSELKRELGQCLDEKQEIATERDIYRNKCDRL...NNEL...NYIL......SGDER............KIQ.DIDTLITESR...MLKEQIQSLEMEKSLALSTITKYKK.LLDR.K...L-..----..........................-------------.------.....-----------..--------------------------------------.----------------tknssvssescmtpa....
H2MYS7_ORYLA/1-122               ...........................-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.------MENR...YLHERINQFQEEVNLLKANLTKYKS.ALES.R...KI..SKIN..........................--GRPNSSALTGV.LSAKQV.....KELLLSEENGC..SLPVTPQSISDLKSLATALLETIHEKNMVIQHQRQINK.VLGNRVAELEMKLKT-i..................
F7C6Z6_MONDO/1-283               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSIPPEK............................rKQANLAQLLSDSRDRNKHLGEEIKELQQRLGEIQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.AR..HFA...................aHEREDLVQQL......ERAREQIESLEHDLQASVDELQDIKEERSSYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...---QRLKQLHEEVSLLKSNIAKYKN.ALERrK...NS..KSQG..........................RSSNSSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B3SAY2_TRIAD/72-401              ...........................KQRLDSKVAALQILHRELASCQLERDLYKTK.YNQLVQERNGETVTSSTTKYS..WDDEKDDNFYTKSldrdar.................yihessRNKGMIQILCDARMQIKRLQLDLDHIRQRFCEAQGDIK.....LLREKAKRR..QQQM..V.RS.L.TQ..EHShi................qeDERKKLVLEL......ESANEKIIQYERFIKDVTDEKSELEIERDSHRDKASRL...NQEL...NYMI......TGDDK............RIY.DIDELIVENR...YLKERLKQCVEEKKIALQTVSKLKS.ALD-.K...CK..LKSV..........................RFNLS-DLTGGSI.MSSSPR.....KS---KAGANL..KVGNASTTFSDLQALATSLQETVTDKNTALLHQRRTNR.ILGARVAELEKKLK--nf.................
H2QPA5_PANTR/26-338              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
F7E6T9_CALJA/3-262               .....................ihhfll-------------------------------.---------------------..-----------KR.............................KQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G1K8G7_ANOCA/1-215               ..........................q-------------------------------.---------------------..-------------.............................--------------------------------------.....LLRMTIAKQ..RLGD..E.EV.G.AR..HFA...................pHEREDLVQQL......EKAHEQIEALQHDLQATLDELQDVKGERSFYQDKSDRL...NQEL...NHVL......GGHVN............RII.DVDALCMENR...YLHERLKQIQEEVNILKSNIAKYKN.ALERrK...NS..KTNN..........................KSN---SSALTGV.LSAKQV.....QELL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
A8XQT7_CAEBR/19-335              ...........................QQKCNAKTDTIVRLGQDLEKSENEKKGYVAR.VETLE---RNLERTEKELGLL..CAVEKDMKIKNAS.............................ERQDLIEDINKYKRENMKLRSDRQELMDEKADLKKDCK.....TFRQTIAQY..EVEK..M.GG.M.VR..TCL....................SNDDEETAMLg...ayEKLQTKCRELESDLKSMLGIKEELLLERDEMQRKVARL...SNEL...SYLL......NGDPR............RVAeDLDSLVAENR...FLKAKLNTAEEESESIKMTLAKYKQ.MAEA.V...NV..QSLNr.......................spKAGEGDEKPSVAV.INMKQI.....RELLTSHAIEL..-------DESDHRAITTILLDLCNDKQMALAHSRRANKsVLGMRLHEVESKLAVL...................
CC149_HUMAN/1-283                ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.AI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B5DXD0_DROPS/368-689             ...........................HRKLQSKVEALRILRLELEQFRVERDQYKLM.AETLQLRYSALKHNS---ELV..TVGGN--GCGPLS.............................QNSSLAALLHETREQNLKLNTEVEGLKQRLNEIQGDME.....LLRETEASN..KARV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......ENLKKKNAQLAFDFKAIIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pKLL.DIDGVLLENK...YLHERVKIQEGELDLTKQSISKYKS.MLDA.K...RK..KGIV..........................KLGGGTSTNDETI.LSPRQV.....KTILESGI---..DLPQKTETIHDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAGKMTDLEQRWQQL...................
H2VWG9_CAEJA/20-336              ...........................QQKCSAKTDTIVRLGEDLERCENEKKTMNAR.VDTLE---RNLERTEGELQLI..CACQDDMKIKFGT.............................ERQDLIEDISKYQRENQKLKTERQELLDEKTDLKKDCK.....TFRQKIAQY..EVER..M.GA.A.VK..KSN....................SNDEEDVEKLe...ahEKLQSRCKELESDLRSLLGIKEELLLERDEMQRKVVRL...SNEL...SYLL......NGDPR............RVAeDLDSLVAENR...FLKAKLNTAEEESESIKMTLAKYKQ.MAEA.V...NV..QSIVnr......................spKAGEGEDKPSVAV.INMKQI.....RELLASHAIEL..-------DESDYRAITTILLDLCNDKQMALAHSRRANK.VLGMRLHEVEAKLAVL...................
G0M6S4_CAEBE/20-336              ...........................QQKCSAKTDTIVRLGQDLERSEEQKKGYAAR.VETLE---RNLERTERELQLV..CACQNDMKIKFGT.............................EKQDLIEDVEKYKRENQKLRCDRQELLDEKADLKKDCK.....TFRQTIAQY..EVEK..M.GG.A.IK..STF....................SSDEGEVAKLe...ahEKLQAKCKELESDLRSMLGIKEELLIERDEMQRKVARL...SNEL...SYLL......NGDPR............RVAeDLDSLVAENR...FLKAKLNTAEEESESIKMTLAKYKQ.MAEA.V...NV..QSMVsr......................spKAGDSEEKPSVAV.INMKQI.....RELLASHAIEL..-------DESDYRAITTILLDLCNDKQMALAHSRRANK.VLGMRLHEVESKLAVL...................
H2YNP2_CIOSA/2-160               .............srrernnsewqali-------------------------------.-------------------AE..ALKRQQADFSMLS.............................DKTKLIRILRDTKNQKLGHQRHSEMLQQKLNEALGDMK.....LLREKFARH..RVGD..E.GI.G.AR..HFP...................vHEREKLVCEL......EQAQQQSKNWYREYVSQTEATSDAKQDTETYRLKAERL...NEEL...NQIL......SGDKS............RIV.DIDAL-----...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------...................
G1S4E8_NOMLE/32-343              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMEN-...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
H2XNP3_CIOIN/22-325              ...........................KRKLQSKSEALLIISKDLETAQKERDQFKMM.AEKLQERCQALKRQQADFAML..------------S.............................DKAKLIRVLRDTKNQKLGHQRHSEMLQQKLNEALGDIK.....LLREKFARQ..RIGD..E.GI.G.AR..HFP...................lHEREKLVSEL......EQAQQQGENWHKEYMCQVEVTMEAKQEAEMYRLKGERL...NKEL...SHVL......SGDKS............RIV.DIDALCMENK...YLQERISQCQKEKNTLHTQVNKYKS.ILIS.K...KTggDESI..........................KLG--NLRSAGTV.VSPKQL.....KQMLLKGFNTN..----SPEQVADLQSIVSALLETINDKNLAMHHLRSTNK.ILGQRVSELEKKLKTL...................
H2UFK8_TAKRU/1-289               ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPPLPPEK............................rKQVDLAQLLRDSRDRSGQLSEEVKELKQRLLEVQGDNK.....LLRMTITKQ..RVGD..E.EV.G.AR..HFP...................aHEREDLVRQL......ERAREQNELLEHSVKSLSDELQDVCAERDVFQQKAHRL...NVEM...NHIV......GSDDA............RIL.DVDALCMENR...YLHQQLNQLQEEILLLKSNIVKYKS.ALECrK...NS..KTFT..........................KPN---SSALTGV.LSTKQVftravKELLQSEENGC..SLPVTPQSISDLKSLATALLETIHEKNMVIQHQRQINK.ILGNRVAELEKKFQTL...................
F6QT63_XENTR/1-283               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSIPPEK............................rKQANLAQLLGDSREKCKKLESEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..D.EV.G.KR..YFA...................pHEREDLVLQL......EKAREQIEALEHDLQASLDELQDVKQERSFFQDKAERL...NQEL...NHVL......GGHEK............RII.DIDALCMENR...YLQERLKQLQEEVNLQKTNLAKYKN.ALEKrR...NS..KSNT..........................KSS---SSALTGV.LSAKQV.....QELL-SEEHGC..SLPATPQSVSDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
Q1DGS4_AEDAE/27-281              ...........................HRKLQSKVEALKIMRNELEKYRSERDQFKLM.AETLQMRYSAMKSSLNSPEFQ..AAGFG--------.............................NSSAVSLLVNQTRERNISLSTEVEALRQRVHELEGDID.....VLRTKNFDL..QAAF..N.KM.K.ST..EETklkdr.........kgivwdEEKSKLIAQM......ETLKKKNAQLQYDVRSLLDEKEDVVMERDAYKCKAHRL...NHEL...SVML......KGDQSq..........qKIV.DVDGLILENK...YQQEKITNLENELELSRQSATKYKN.MLDT.K...RK..KGII..........................KLG---TNNNQRV.MSHSQ-.....-----------..--------------------------------------.----------------...................
G1LPB2_AILME/26-338              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLAEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQS..........................KSS---SSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
Q7PTQ8_ANOGA/37-361              ..........................s-RKLQSKVEALKIMRYELEKCRTERDQFKLM.AETIQLRYSAIKNSLNAPDFQ..AAGFG--------.............................NSSAVSLLVKQTRERNEALTTEVESLKQRLYDLEGDIK.....VVRARNVEL..QDTC..G.KL.R.AT..NESllstn.........gdktwqAEKSQLIAQL......EQLRKRNAQLQYDFRSLLDEKEETVTERDAYKCKAHRL...NHEL...NVALrgaggaGGASQ............TLL.DIDGLILENK...YQAEKIANIENELSLARQAASKYKS.MLET.N...RK..KGII..........................KLG--TNNNNKTI.MSHSQV.....KHLLENGTVD-..ELPLKAATISDLKSLCLALLDNVNDKSLALSHQKKTNK.LLATKIAELERHIKTL...................
H3A7B3_LATCH/6-318               ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLREKHQSLKKKYRELI--..---DGDPTLPPEK............................rNQANLAQLLSDSRERSKQLAEEIKELQQRLAEAQGDNK.....ILFKKKKKK..KNLD..S.SI.V.SR..AFF...................lHEHLDRVQYI......EKIWEEIETLEHDLQAALDELQDVKVERSFYQEKTERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLQEEVTLQKSNIAKYKN.ALERrK...NS..KSSS..........................RSN---SSALTGV.LSAKQV.....QELL-SEEHGC..SLPATPQSISDLKSLATALLETIHEKNIVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G3Q7L3_GASAC/1-267               ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rNQVNLAQLLRDARERAKQLAEEVKELTQRLTEAQGDNK.....LLRMTITRQ..RLGD..E.EV.G.AR..HFP...................aHEREELVRQL......ERAGLQMEEMEHNLKAVTDELQDVKSERSVFREKAHRL...NVEL...NHVL......GNREA............RII.DVDALCMENR...YLHERFSQLQEEVNLLKSNIMKYKT.ALER.-...RK..N-ST..........................AYGKSNSNPLTGV.LSAKQV.....QELLLEER-GC..SLPATPQSISDLKSLATALLETIHEKNLVIQHQRHTNR.----------------...................
G3W7F9_SARHA/15-318              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSIPPER............................rKQANLAQLLSDSRDRNKHLGEEIKELQQRLGEIQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.AR..HFA...................aHEREDLVQQL......ERAREQIESLEHDLQASVDELQDIKEERSSYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEENALERR-------.----.K...NS..KGQS..........................KSSHNSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G4LXA6_SCHMA/2-209               sryqvlrktlmecdeadqystpdimhl-------------------------------.---------------------..-------------.............................STKQLASLLVESREANKSLEHELMNSREKIEELQGDIK.....VLRKQLSDR..SCEN..QhTM.D.PR..VSG....................NDRQAYVTQL......EELTFQLSELKRELGQCLDEKQEIATERDIYRNKCDRL...NNEL...NYIL......SGDER............KIQ.DIDTLITESR...MLKEQIQSLEMEKSLALSTITKYKK.LLDR.K...L-..----..........................-------------.------.....-----------..--------------------------------------.----------------tknssvssescmtpa....
E9JD86_SOLIN/1-310               ...........................KRELQMKSEALILLSQKMEQCRTQRDQFKLM.AEQIQERFLHLKKQMCDMK--..ELNGYNSGLYLDD.............................DFRTL-DLLTEVREQNKCLRLQVDTLRQKLADAEGDIK.....VLRMNNNRM..PIEQ..Q.ET.Q.LA..PAM....................HQREEMIEQL......EKLNLKCSQLQTDLQTVLDEKHELEVERDAFKCKAHRL...NHEL...SKAL......NA--T............KPV.DLDALINENR...YLQERLQQLLEEKELTRQSLSKYKS.MLDS.K...RT..KGAI..........................KLG--ANSAAGTV.MTHKQV.....EQLLQESSYI-..PPQKSAAAVTDLRCLCTALLEALNDKTLALAHQKKANK.ILALRICELDSAV---qs.................
F7HVV9_CALJA/6-318               ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
C149B_DANRE/1-284                ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rNQVNLAQLLRDSREHNKQLSEELKELKQRLAEVHGDNK.....LLRMTIAKQ..RLGD..E.EV.G.TR..HFP...................aHEREDLVQQL......ERAREQTEALEQSLKAATDELQDVRAERNVYQEKAHRL...NLEI...NHIL......GSHEN............RIL.DIDALCMENR...YLHERLMQLQEEVSLLKSNVMKYKS.ALES.K...KN..CKVY.........................gKSN---SSALTGV.LSAKQV.....QELLLSEENGC..SLPVTSQSISDLKSLATALLETIHEKNMVIRHQRQTNK.ILGNRVAELERKLKTL...................
B4PS33_DROYA/27-345              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLV.AETLQLRYSALKSNS-ELL--..AVGGC----GALS.............................ENSSLAALLHETREQNLKLSTEVEALRQRLNELHGDME.....LLRETEASN..KSRV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......EGLKKRNAQLAFDLKAVIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pRLL.DIDGVLLENK...YLHERVKIQDSELELTKQSINKYKT.MLDA.K...RK..KGIV..........................KLS-GGGTNEDTI.LSPRQV.....KTILESGI---..DLPQKTESLSDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAAKMTELEQRWQQL...................
B4HM16_DROSE/27-154              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLV.AETLQSRYSALKSNS-ELL--..AVGGC----GALS.............................ENSSLATLLHETREQNLKLSTEVEALRQRLNELHGDME.....LLRETEASN..KSRV..Q.AM.A.SE..NAA....................RNKESA----......--------------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------vppw...............
I1GEI8_AMPQE/29-318              ...........................KRKLRSKEEAIRILHRELELSQEEKEEFSRL.MNHMKDYYLEGQSPNDSTDYE..SLEFPDQSII---.............................---------SMSVDRVTQLEGLIKQLRHKH---KEEVQ.....SLKEKLSQA..RGVL..M.PS.P.AS..LGTd.................faEEKARLISQL......EAAQSQIMSLVREVQSLEDEKEEAMTERDAFAGKCNTL...NKML...EERV......NDKVP............SRS.TFEKLLDENR...QLKLELIETQADRDSAINKIDRYKR.TVE-.R...KK..NRDT..........................------QNQAIQF.MSSEKL.....SA---------..-LRQSVRRVQELEVLANSLSEEVKEKSLALSHSRKTNR.LLGTRIAELEHRLKVL...................
O18529_RHYAM/22-280              .......................ihkp--------EACTCTFRTLDECRYAYDELKNDyLESIA-IREAQEKERKDLIQQ..VQVANDKICKLSE.............................ENHNLSVAVKQYKEENKNLKETIGSLKKTIEELKKQ--.....-LSKAQEDL..RSCG..N.AL.E.CC..N--....................REKEALLRTI......YELECKIKQLQEEINGYKEEIAKLNKELDEFKHKLARCekeNREK...QQLI......NEYKC............K--.-IESLIEEIR...KLKQQLSACENERNDLKCSINKYFA.ITS-.K...LE..SNFS..........................QHFASAQKAFIGI.TT----.....-----------..--------------------------------------.----------------ardgfpnlksatcvesrpc
G7Y3A9_CLOSI/5-188               ...............qllrktvcqdtp-------------------------------.---------------------..-------------.............................--VELASLLVESHEANKGLQQELVEMKVKLSEALGDIK.....LLRKQLKS-..PVFG..P.PI.T.QK..TEL....................DEKEKWVLQM......EKLTERVNELERELARCCDDKQELVTERDIYRNKCDRL...NNEL...NYIL......NGDDR............KIV.DIDTLIMEKR...LLNSRLRALEEEKRLAMATLTKYQR.MMER.K...AS..KT--..........................-------------.------.....-----------..--------------------------------------.----------------ssvgsdc............
F1QC51_DANRE/1-283               ...........................------------------------------M.ANQLRETHQSLKKKYRELI--..---DGESSLPPEK............................rNQVNLAQLLMDSRERNKQLAEEVKEVTQRLSETQGDNK.....LLRMTITKQ..RLGD..D.EV.G.IR..HFP...................aHEREDLVRQL......EKAALHREELEHTLKTLSDELQDVKAERTVFKEKSERL...NLEL...NHIL......GGQEK............RII.DVDALCMENK...YLHERLKQVQEEVSLLKSNIQKYKT.ALD-.R...RK..NPEI..........................-GGKSSSRSLTGV.LSPKQV.....HGFL-SEENGC..SLPATPQSISDLKSLATALLETIHEKNIIIQHQRQTNR.ILGNRVADLERKLKTL...................
E2C5S8_HARSA/25-331              ...........................KRKLQMKSEALMLLSQELDQCRIQRDQFKLM.AEQIQERFLHLKKQMCDTKEL..NRCYN-----LDD.............................D-FRTLDLLTEAREQNKCLRLQVETLRQKLGDAEGDIK.....ALRMNNNRV..SVEQ..Q.DT.Q.LA..PSM....................HQREEMIEQL......EKLNLKCSQLQTDLQTVLDEKHELEMERDAFKCKAHRL...NHEL...SKAL......NA--S............KPV.DLDALINENR...YLQERLQQLLEEKELTRQSLSKYKS.MLDS.K...RT..KGAI..........................KLG--ANSAVGTV.MTHKQV.....EQLLQESSYI-..PPQKSAAAVTDLRCLCTALLEALNDKTLALAHQKKANK.ILALRICELDSAV---qs.................
H2YNP1_CIOSA/22-204              ...........................KRKLQSKSEALLIISQDLETAQKERDQFKLM.AEKLQERCQALKRQQADFSM-..-----------LS.............................DKTKLIRILRDTKNQKLGHQRHSEMLQQKLNEALGDMK.....LLREKFARH..RVGD..E.GI.G.AR..HFP...................vHEREKLVCEL......EQAQQQSKNWYREYVSQTEATSDAKQDTETYRLKAERL...NEEL...NQIL......SGDKS............RIV.DIDAL-----...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------...................
D6RDA1_HUMAN/26-229              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.AI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------qvpsreik...........
H9IG47_ATTCE/25-313              ...........................KRKLQMKSEALILLSKEMDQSRIERDQFKLM.AEQIQERFLHLKKQMCDMK--..--ELN----NFDD.............................DFRT-LDLLTEAREQNKCLRLQVETLRQKLTDAEGDIK.....VLRTNNNRI..PIEQ..Q.ET.Q.LA..PAM....................HQREEMIEQL......EKLNLRCSQLQTDLQTVLDEKHELKMERDAFKCKAHRL...NHEL...SKAL......NA--T............KPI.DLDALINENR...YLQERLQQLLEEKELTRQSLSKYKS.MLDS.K...RA..KGTI..........................KLG--ANSAVGTV.MTHKQV.....EQLLQESSYI-..PPQKSAAAVTDLRCLCTALLEALNDKTLALAHQKKANK.----------------...................
Q93635_CAEEL/20-336              ...........................QQKCGAKTDTIVRLGQDLEKSENEKKGLAAR.VETLE---RNLERSERELQLV..CACQNDMKIKFGT.............................ERQDLIEDIEKYKRENQQLRTDRQELLDQKADLKKDCK.....TFRQTIAQF..EVEK..M.GG.P.VR..NSF....................STENDEVSKLe...ahEKLQAKCKGLESDLRSMLGIKEELLMERDEMQRKVARL...SNEL...SYLL......NGDPR............RVAeDLDSLVAENR...FLKAKLNTAEEESESIKMTLAKYKQ.MAEA.V...NV..QTMVnr......................spKAGEGDDKPSVAV.INMKQI.....RELLASHAIEL..-------VESDYRAITTILLDLCNDKQMALAHSRRANK.VLGMRLHEVESKLAVL...................
F1PAT3_CANFA/1-256               ..........................q-------------------------------.---------------------..-------------.............................--ANLAQLLRDSQDRNKHLGEEIKELQQRLAEVQGDNKkwkmqLLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ETAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQS..........................KSS---SSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G3ID80_CRIGR/202-295             .........................rn-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.----------...-------------------------.ALERrK...NS..KGQ-..........................--GKSSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSIADLKSLATALLETIHEKNMVIQHQRQTNR.ILGNRVAELEKKLRTL...................
E0W0A1_PEDHC/26-335              ...........................KRQLESKSEALLILNKELAECRSERDQFKLM.AEKLQEKCSTLKKNSFKES--..-------SLFNDN.............................YDEPISPTSSDSKDVNRSLKFEVDCLRQKLRDALGDVK.....ALRNQLNEQ..KLMP..V.GI.D.SLslKHL....................DKQEALVKQI......EAMHKLKNQLEIDLQSVIDEKEELITQRDAYKCKVHRL...NHEF...SVLL......KSSNH............SVI.DIDSLIMENR...FLQEHLQQAQEEINLVNQTSNRYKS.LLEK.K...HN..KGAI..........................KLA---LENLSGIsLSPEQV.....QELFETNSTEQ..IPNSVAATISDLKFMCLALLEYSNDKILALSHQKRANR.ILAAQICELEHRVENL...................
I0FW89_MACMU/26-338              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYREMI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B4NA37_DROWI/36-356              ...........................HRKLQSKIEALRILRQDLEQFRVERDQYKLM.AETLQLRYSALKRNSELLVNE..SHGC-----GALS.............................ENSSLAALLRETREHNLKLNTEVEALKQKLHELQGDIK.....LLRETEASNktRVEA..M.AN.E.TA..AHNkee.............lqwkRERANFICHL......ENLKKKNAQLAFDFKAIIDEKEELITERDAYKCKAHRL...NHEL...FVAL......KAKKMh..........pKLL.DIDGVLLENK...YLHERVKIQESELELSKQSINKYKT.MLEA.K...RK..KGIV..........................KLG-GGNSNDDTI.LSPRQV.....KNILESGI---..DLPKKTETIHDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAGKMTELEQRWQQL...................
E5SCH7_TRISP/1-181               .........................mv-------------------------------.---------------------..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......-----------------LCEKEELTIERDGYQTKFNKV...NQEL...YALL......NGSGN............NIP.DVEDLLSENR...FLKQQVESLKEENLTSKTILSKYKK.AIE-.-...KR..KGVMrfgfsaagdsssndkagvaplttptvKQTTVANSTDVPL.YTIKQI.....VQAIEKDRNTN..------CLNLDYRQISHMLLDAINDKTVAVMHLRKANK.IYGQKL----------pmmi...............
Q4S6J5_TETNG/22-335              ...........................KQKLESKTEALLILSKELDTCQQERDQFKLM.ANQLRERHQGLKKKYSELM--..---DGDPSLPPEK............................rKQVNLAQLLRDCRDKNSQLSEEVKELKQRLLEVQGDNK.....LLRMTITKQ..RVGD..E.EV.G.AR..HFP...................aHEREDLVQQL......ERAREQSEILEHSVKSLTDELQDVCAERDVFQQKAHRL...NVEM...NHLV......GNEDT............RVL.DVDALCMENR...YLHQQFNRLQEEVILLKSNIVKYKS.ALECrK...NS..KTFM..........................KPN---SSALTGV.LSTKQV.....KELLQSEENGC..SLPVTPQSISDLKSLATALLETIHEKNMVIQHQRQINK.ILGNRVAELEKKFQTL...................
F4HID0_PYRSN/104-248             ..................ivvnpkess-----------------ISKYISEISKLKNK.IAELTKENEQLNEKIKELNQK..LSQNGKQQSTQTKq..........................pqNFNQLQLKILNLTKENRKLKEELANLTKKYNALKGENQ.....YLKEQLKTY..QAVF..S.GL.V.SR..VEQ....................HAESDYIEQA......KKSKKTAERL----------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------fisii..............
D2I2A4_AILME/8-321               ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLAEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR..qYLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQS..........................KSS---SSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
C149A_DANRE/1-283                ...........................------------------------------M.ANQLRETHQSLKKKYRELI--..---DGESSLPPEK............................rNQVNLAQLLMDSRERNKQLAEEVKEVTQRLSETQGDNK.....LLRMTITKQ..RLGD..D.EV.G.IR..HFP...................aHEREDLVRQL......EKAALHREELEHTLKTLSDELQDVKAERTVFKEKSKRL...NLEL...NHIL......GGQEK............RII.DVDALCMENK...YLHERLKQVQEEVSLLKSNIQKYKT.ALD-.R...RK..NPEI..........................-GGKSSSRSLTGV.LSPKQV.....HGFL-SEENGC..SLPATPQSISDLKSLATALLETIHEKNIIIQHQRQTNR.ILGNRVADLERKLKTL...................
F4WMZ9_ACREC/29-332              ...........................KRKLQMKSEALMLLSKEMDQSRIERDQFKLM.AEQIQERFLHLKKQMCDMK--..--ELN----SFDD.............................DFRT-LDLLTEAREQNKCLRLQVETLRQKLTDAEGDIK.....VLRTNNNRI..PIEQ..Q.ET.Q.LA..PAM....................HQREEMIEQL......EKLNLKCSQLQTDLQTVLDEKHELKIERDAFKCKAHRL...NHEL...SKAL......NA--T............KPV.DLDALINENR...YLQERLQQLLEEKELTRQSLSKYKS.MLDS.K...RA..KGTI..........................KLG--VNSAVGTV.MTHKQV.....EQLLQESSYI-..PPQKSAAAVTDLRCLCTALLEALNDKTLALAHQKKANK.ILALRICELDSAIQ--s..................
H2PD14_PONAB/6-318               ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
E7FE63_DANRE/22-334              ...........................KRKLESKKDALLILSKELDTCQQERDQYKLM.ANQLRETHQSLKKKYRELI--..---DGESSLPPEK............................rNQVNLAQLLMDSRERNKQLAEEVKEVTQRLSETQGDNK.....LLRMTITKQ..RLGD..D.EV.G.IR..HFP...................aHEREDLVRQL......EKAALHREELEHTLKTLSDELQDVKAERTVFKEKSERL...NLEL...NHIL......GGQEK............RII.DVDALCMENK...YLHERLKQVQEEVSLLKSNIQKYKT.ALD-.R...RK..NPEI..........................-GGKSSSRSLTGV.LSPKQV.....HGFL-SEENGC..SLPATPQSISDLKSLATALLETIHEKNIIIQHQRQTNR.ILGNRVADLERKLKTL...................
F7B7V3_HORSE/1-282               ...........................------------------------------M.ANQLRERHQSLKKKHRELI--..---DGDPSIPPEK............................rKQANLAQLLRDCQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMEN-...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
F6WD54_ORNAN/5-262               .....................ilwshf-------------------------------.---------------------..-------------.............................-QANLVQLLSDSRDRNHHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......EKAREQIESLEHDLQASVDELQDVKDERSSYRDKVDRL...NQEL...HHIL......GGHEN............RII.DVDALCMENR...YRRKRKPLWIGSLRTLKSNLFVYVNsALE-.R...RK..NS-K..........................SQGRSSSSSLTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
H3JFA4_STRPU/20-317              ...........................KRKHQAKSDALLVLAKELDNVRQEKDAYKLM.AEQLREKFHEQRKKYEERE--..-------------.............................--RTLVQILCESRAKNRKAELELVDLHQKLSEAEGDIK.....LLRESIARQ..RIGD..E.GI.G.TR..HFP...................aHEREELIRQL......EKSREQIESLERDMVAKIDDQQEFVTERDYYRTKTERL...NQEL...NYVL......GGDDR............RII.DVDALVMENK...YLKERMNQSLEEKATLQQTINKYKT.ALER.R...RG..KGIG..........................RPG----SGTGSV.LSTKDV.....ENLLAQGKSG-..GISASPSSVGDLQALATSLLETVHDKNMALSHQKNTNK.ILGKRVAELEKKLKTL...................
G3R3U2_GORGO/26-338              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G1ST40_RABIT/1-286               ...........................------------------------------M.ANQLRERHQSLKKKYRELI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNKk..mqLLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......EQAKEQIEALEHDLQASVDELQDVKEERCSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSVSDLKSLATALLETVHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
Q16UI1_AEDAE/24-343              ...........................HRKLQSKVEALKIMRNELEKYRSERDQFKLM.AETLQMRYSAMKSSLNSPEFQ..AAGFG--------.............................HSSAVSLLVNQTRERNISLSTEVEALRQRVHELEGDID.....VLRTKNFDL..QAAF..N.KM.K.ST..EETklrdr.........kgivwdEEKSKLIAQM......ETLKKKNAQLQYDVRSLLDEKEDVVMERDAYKCKAHRL...NHEL...SVML......KGDQSq..........qKIV.DVDGLILENK...YQQEKITNLENELELSRQSATKYKN.MLDT.K...RK..KGII..........................KLG---TNNNQRV.MSHSQV.....KDLLERGTVE-..ELPLKAATISELKSLCLALLDNVNDKSLALSHQKKTNK.LLAAKITELEQRILAL...................
E3WMC5_ANODA/81-335              ..........................s-RKLQSKVEALKILRYELEKCRTERDQFKLM.AETIQLRYSAIKNSLNSPDFQ..AAGFG--------.............................NSSAVSLLVKQTRERNEALTTEVESLKQRLYDLEGDIK.....VVRARNVEL..QDTC..N.KL.H.TA..NESiltan.........gdkkwqENKSQLIAQL......ELLRKRNAQLQYDFRSLLDEKEEVVTERDAYKCKVHRL...NHEL...TVAL......QGATGkge.....gspqPLL.DIDALVLENK...YQAEKIATVENELLLARQAASKYKL.LAGC.D...DR..TTL-..........................-------------.------.....-----------..--------------------------------------.----------------aslspsqylln........
H2LJ92_ORYLA/1-267               ...........................------------------------------M.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rNQVNLAQLLRDSRERVKQLSEEVKDLTQRLAEAQGDNK.....LLRMTITKQ..RLGD..D.EV.G.VR..HFP...................aHEREDLVSQL......ERAGLQMEEMENSIKALTDELQDVKAERSVFKEKADRL...NVEL...NHIL......GNHES............RII.DVDALCMENR...YLHERFTQLQEEVTLLKSNIMKYKT.ALE-.R...-R..KNSS..........................PHGRSSNTPLTGV.LSAKQV.....QEMLLEEQ-GC..SLPLTPQSISDLKSLATALLETIHEKNLVIQHQRHTNR.----------------...................
CC149_XENLA/1-283                ...........................------------------------------M.ANQLRERHQSLKKKYGELI--..---DGDPSVPPEK............................rKQVNLAQLLGDSREKCKKMESEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..D.EV.G.KR..HFA...................pHEREDLVLQL......EKAKEQIEAFEHDLQASLDELQDVKQERSFFQDKAERL...NQEL...NHVL......GGHEK............RII.DIDALCMENR...YLQERLKQVQEEVNLQKSNLVKYKN.ALEKrR...NS..KSNT..........................KLS---SSALTGV.LSAKQV.....QELL-SEEHGC..SLPATPQSVSDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G5B026_HETGA/41-100              ...........................KRKLDSKKEALLILSKELDACQQERDQFKLM.ANQLRERHQSLKKKYRELIIY..-------------.............................--------------------------------------.....---------..----..-.--.-.--..---....................----------......--------------------------------------...----...----......-----............---.----------...-------------------------.----.-...--..----..........................-------------.------.....-----------..--------------------------------------.----------------vkelgtis...........
G8F4U0_MACFA/1-283               ...........................------------------------------M.ANQLRERHQSLKKKYREMI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G1U7G1_RABIT/6-267               ..................llhsqrclt-------------------------------.---------------------..-------------.............................--ANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNKk..mqLLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......EQAKEQIEALEHDLQASVDELQDVKEERCSYQDKVERL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSVSDLKSLATALLETVHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
G3W7F8_SARHA/26-341              ...........................KRKLESKKEALLILSKELDTCQQERDQYKLM.ANQLRERHQSLKKKYRELI--..---DGDPSIPPER............................rKQANLAQLLSDSRDRNKHLGEEIKELQQRLGEIQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.AR..HFA...................aHEREDLVQQL......ERAREQIESLEHDLQASVDELQDIKEERSSYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...YLQERLKQLHEEVSLLKSNIAKYKN.ALERrK...NS..KGQS..........................KSSHNSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B3LZR9_DROAN/27-345              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLV.AETLQLRYSALKTNN-ELL--..AVGGC----GALS.............................ENSSLAALLHETREQNLKLSTEVEALRQRLNELQGDME.....LLRETEASN..KSRV..Q.AM.A.TE..NAArnke...........evqwrRERANFICHL......EGLKKRNAQLAYDLKAVIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pRLL.DIDSVLLENK...YLHERVKIQESELELSKQSITKYKT.MLDA.K...RK..KGIV..........................KLG-GGSTNEETI.LSPRQV.....KSILESGI---..DLPQKTETIHDLKSLCLALLDNLNDKNLALSHQKKTNK.ILAGKMTELEQRWQQL...................
F6URH4_MONDO/1-251               ..........................q-------------------------------.---------------------..-------------.............................--ANLAQLLSDSRDRNKHLGEEIKELQQRLGEIQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.AR..HFA...................aHEREDLVQQL......ERAREQIESLEHDLQASVDELQDIKEERSSYQDKVDRL...NQEL...NHIL......GGHEN............RII.DVDALCMENR...---QRLKQLHEEVSLLKSNIAKYKN.ALERrK...NS..KSQG..........................RSSNSSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
B3P0W5_DROER/27-345              ...........................HRKLQSKVEALRILRQELEQFRVERDQYKLV.AETLQLRYSALKSNS-ELL--..AVGGC----GALS.............................ENSSLAALLHETREQNLKLSTEVEALRQRLNELHGDME.....LLRDTEASN..KSRV..Q.AM.A.SE..NAArnke...........elqwrRERANFICHL......EGLKKRNAQLAFDLKAVIDEKEELITERDAYKCKAHRL...NHEL...FVAL......RAKKTh..........pRLL.DIDGVLLENK...YLHERVKIQDSELELTKQSINKYKT.ILDA.K...RK..KGIV..........................KLG-GGGTNEDTI.LSPRQV.....KTILESGI---..DLPQKTESLSDLKSLCLALLDNLNDKNLALTHQKKTNK.ILAGKMTELEQRWQQL...................
E2A489_CAMFO/24-330              ...........................RRKMQMKSEALLLLSQELDQCRIQRDQFKLI.AEQIQERFLQLRKQMCETKES..NRCY-----S-SN.............................DDFRTLDLLTEAREQNKCLRLQVETLRQKLADAEGDIK.....ALRTNSNRT..SVQQ..Q.EA.Q.LA..PTM....................HQREEMIEQL......EKLNLKCSQLQTDLQIVLDEKHELEMERDAFKCKAHRL...NHEL...SKAL......SA--S............KPV.DLDALINENR...YLQERLQQLLEEKELTRQSLSKYKS.MLDS.K...RT..KGNI..........................KLG--VNSAAGTV.MTHKQV.....EQLLQESSYIP..-PQKSVAAVTDLRCLCTALLEALNDKTLALAHQKKANK.ILALRICELDSAV---qs.................
B4M6H0_DROVI/50-369              ...........................HRKLQSKVEALRILRQEMEQFRVERDQYKLM.AETLQLRYSAMKRNSELLA--..--GNG-NACGALS.............................QNSSLAALLHETRELNLKLNTEVEALKQRLGELQGDME.....LLRERESNS..KSRL..Q.AL.L.TE..NAAhnke...........elqwkRERANFICHL......ENLKKKNAQLAFDLKAIIDEKEELMTERDAYKCKAHRL...NHEL...LVAL......KANKMh..........pNLL.DIDGVLLENK...YLHERVKIQESELELTKQSVSKYKS.MLEA.K...RK..KGIV..........................KLG--GSTNDETI.LSPRQV.....KTILESGI---..DLPGKTETIHDLKSLCLALLDNLNDKNLALTHQKRTNK.ILASKMSELEQRWQQL...................
F6SES1_MACMU/1-283               ...........................------------------------------M.ANQLRERHQSLKKKYREMI--..---DGDPSLPPEK............................rKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNK.....LLRMTIAKQ..RLGD..E.EI.G.VR..HFA...................aHEREDLVQQL......ERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERL...NQEL...NHIL......SGHEN............RII.DVDALCMENR...YLQERLKQLHEEVNLLKSNIAKYKN.ALERrK...NS..KGQG..........................K---SSSSALTGV.LSAKQV.....QDLL-SEDHGC..SLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELEKKLRTL...................
E7F2N0_DANRE/22-335              ...........................KRKLESKKEALLILSKELDTCQQERDQFKLM.ANQLRERHQGLKKKYRELI--..---DGDPSLPPEK............................rNQVNLAQLLRDSREHNKQLSEELKELKQRLAEVHGDNK.....LLRMTIAKQ..RLGD..E.EV.G.TR..HFP...................aHEREDLVQQL......ERAREQTEALEQSLKAATDELQDVRAERNVYQEKAHRL...NLEI...NHIL......GSHEN............RIL.DIDALCMENR...YLHERLMQLQEEVSLLKSNVMKYKS.ALES.K...KN..CKVY.........................gKSN---SSALTGV.LSAKQV.....QELLLSEENGC..SLPVTSQSISDLKSLATALLETIHEKNMVIQHQRQTNK.ILGNRVAELERKLKTL...................
#=GC seq_cons                    .........................................................M.AppLp.RapsLK+p.p-h........ts.......p.............................ppssLupLLp-op-cN+pLspElcpLpQRLsElQGDsK.....LLRhTlA+p..+lsc..p.pl.u.s+..phs...................tHERE-LVpQL......E+h+cphcpLcaDLpuslDEhp-lppERssYpsKscRL...NpEL...salL......uGccs............RIl.DlDALhhENR...YLpERlpplpEElpLhKpslsKYKs.hL-t.K...pp..Ks.h..........................K.t...soshssV.LSsKQV.....pplL.Spt.t...sLPhpspoloDLKSLssALLEslp-KNhslpHQ+pTNK.ILus+lsELEp+lptL...................
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