GenomeNet

Database: Pfam
Entry: DUF2393
LinkDB: DUF2393
Original site: DUF2393 
#=GF ID   DUF2393
#=GF AC   PF09624.8
#=GF DE   Protein of unknown function (DUF2393)
#=GF PI   CHP02588; 
#=GF AU   TIGRFAMs, Coggill P
#=GF SE   TIGRFAMs
#=GF GA   24.60 24.60;
#=GF TC   25.10 26.40;
#=GF NC   24.30 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR013417;
#=GF CC   The function of this protein is unknown. It is always found as
#=GF CC   part of a two-gene operon with IPR013416, a protein that appears
#=GF CC   to span the membrane seven times. It has so far been found in
#=GF CC   the bacteria Nostoc sp. PCC 7120, Agrobacterium tumefaciens,
#=GF CC   Rhizobium meliloti, and Gloeobacter violaceus.
#=GF SQ   43
#=GS H5VDX2_HELBI/34-175      AC H5VDX2.1
#=GS B9KDT4_CAMLR/20-176      AC B9KDT4.1
#=GS E0ST17_IGNAA/11-137      AC E0ST17.1
#=GS A0RMR9_CAMFF/19-177      AC A0RMR9.1
#=GS E0UQN1_SULAO/22-165      AC E0UQN1.1
#=GS B6BI05_SULGG/27-170      AC B6BI05.1
#=GS Q30PD4_SULDN/20-186      AC Q30PD4.1
#=GS A0A099V8H3_9HELI/27-176  AC A0A099V8H3.1
#=GS Q0PBN8_CAMJE/30-176      AC Q0PBN8.1
#=GS B9KDT3_CAMLR/32-178      AC B9KDT3.1
#=GS B9L6F7_NAUPA/20-183      AC B9L6F7.1
#=GS E8V8M3_TERSS/63-169      AC E8V8M3.1
#=GS J1F8M3_9HELI/27-177      AC J1F8M3.1
#=GS E8X3Y1_GRATM/63-170      AC E8X3Y1.1
#=GS C1F7T9_ACIC5/67-209      AC C1F7T9.1
#=GS E4TXY0_SULKY/15-176      AC E4TXY0.1
#=GS E4TXY1_SULKY/27-171      AC E4TXY1.1
#=GS B9D5P9_CAMRE/31-175      AC B9D5P9.1
#=GS D1AZ76_SULD5/19-178      AC D1AZ76.1
#=GS A7GWD4_CAMC5/5-183       AC A7GWD4.1
#=GS Q7MSU8_WOLSU/33-177      AC Q7MSU8.1
#=GS C6RHS4_9PROT/31-175      AC C6RHS4.1
#=GS I7GZ81_9HELI/31-176      AC I7GZ81.1
#=GS E7AD80_HELFC/33-174      AC E7AD80.1
#=GS Q0PBN9_CAMJE/19-169      AC Q0PBN9.1
#=GS C6RHS3_9PROT/9-177       AC C6RHS3.1
#=GS F8KR33_HELBC/34-175      AC F8KR33.1
#=GS B9D5Q0_CAMRE/8-177       AC B9D5Q0.1
#=GS D1AZ77_SULD5/32-179      AC D1AZ77.1
#=GS A7GWD5_CAMC5/31-176      AC A7GWD5.1
#=GS Q30PD3_SULDN/26-169      AC Q30PD3.1
#=GS A0RMS0_CAMFF/3-146       AC A0RMS0.1
#=GS K4RIZ1_HELHE/37-178      AC K4RIZ1.1
#=GS C3XMM2_9HELI/32-177      AC C3XMM2.1
#=GS Q1IVJ8_KORVE/24-169      AC Q1IVJ8.1
#=GS Q7VJ04_HELHP/1-119       AC Q7VJ04.1
#=GS I3ZJQ2_TERRK/25-171      AC I3ZJQ2.1
#=GS E0UQN0_SULAO/14-182      AC E0UQN0.1
#=GS B6BI06_SULGG/11-181      AC B6BI06.1
#=GS O25031_HELPY/36-179      AC O25031.1
#=GS D3UJ86_HELM1/27-168      AC D3UJ86.1
#=GS G8NVX1_GRAMM/27-175      AC G8NVX1.1
#=GS C5ZY05_9HELI/34-180      AC C5ZY05.1
H5VDX2_HELBI/34-175                 ..........................................FLCFFIAGLVVRGYT--..ATF..LYLLSF..V..CLFGA.PFGVHYLLEQQLFKIHTKVEQAYAFTYTDA.FEARVQITNEGRMTIRQCALRLDVLKPASNK........................-PQEFLYQWLFEHTYIQTFKVVLAPK.QTHSFNLSIEHYPY..-KQTP...FKLSSACY............
B9KDT4_CAMLR/20-176                 .......................................glt---WVLLYLKVQNKKYM..-II..FCAVSF..I..LALIL.TISLLLTIDQYTKKASLSNFSTYRRLATES.IIVKGRVTNDTNFKISECFLELRIIDDNKKHevsgei............fnqqnfDSIKRANQEQRDASYNINIAKNLPGH.TYKDFSFEVGLPPH..FQSYK...VFKQLKC-k...........
E0ST17_IGNAA/11-137                 ................................sellalvlgl-----------------..-AI..TIAIGI..A..FYAFL.PSFLNTSLQQQ--KIAVSISSATLLTSNEA.VMI-INVKNLGSKNIENFSISVEVENAKGIKv......................nSTREEICSSSHQSTNTLECSYPIQPG.QE--FSL-------..-----...--------pikvfnsgfkvg
A0RMR9_CAMFF/19-177                 ..........................................FLAFLFLSIKEKKVSVV..-LS..MVLLNI..F..VMTSV.SILAMLIIDEYTKIARIVQLDQNRVLINES.IVFTGTIQNTGSHTITNCKFNIRLVNSPVEKgkldpti..........fqtrgffEIFKRKDTQSSTQNASFTIGHGLKAG.ETRAFSVSMNYPAH..FRSPS...VYHTLSCH............
E0UQN1_SULAO/22-165                 ..........................................FILFIIFALLLRKKLIV..ALF..FIFLGF..A..TLVLG.PTFGYIQMHKYIFKNSTKLLSQKKLNFVQA.VVVKGTITNESKFDFGECKITAEVYKVTKNK........................-YKNYLFKLKPFQKMS-ILEQNLPKG.QMREFKIIIEPFRY..QKDYN...ISLGASC-k...........
B6BI05_SULGG/27-170                 ..........................................FILFIILGIVLRKKIAL..AIL..LILLAF..T..ILLAG.PTIGYVKMHDYIFKNTTELTSQKKLSFTQA.VVVKGKITNESKRFFNSCNITASANKVSNNE........................-LKNYLYSFKSFANMS-IMEQNIAVG.ETREFKIIIEPFTY..SKDFN...VSIGAKC-k...........
Q30PD4_SULDN/20-186                 .......................................lgv---GVFFALKQKKQSMV..-FS..IIFSVL..L..ITILM.SAVSIVVIDKYTKIAKLYKLENKRNLSTEQ.IMYSGIVRNEGDYEIGEVTFEIKLVNKGHVSgnvkagtffsprgffdffdfiisdESRKDTKPQQ--IEYKFVVAKNLKPK.ESQEFRVYFDYPPY..FSSVS...HFSNVSAH............
A0A099V8H3_9HELI/27-176             ........................................am--CFVFLSFISFRRKII..SIP..LFLLGF..C..IIIAI.PFAMRYFMEERFYKIEKEIAYDRTYNYSDV.YQYIATITNVGKRNIAGCVFSHQILYDTDNEqg...................itkYKYKILNLIKPKKVYNRDIPMDLKVG.QSVKISEVIENYAH..KGE-K...YITKIECY............
Q0PBN8_CAMJE/30-176                 ..........................................FTCVLLLCVFLRHRPIA..ALF..IIAFDI..I..ICFLV.YIYGYKLIDNEVRTRKIAITDQKMIQSSND.LIVDFNITNNSKNNFKECKITAKIFADKIPNd......................nIIEEYKKKFIPFRQKSREIK-DLKKN.ATQVQRIAFENFNY..ENNYT...IRLVSECF............
B9KDT3_CAMLR/32-178                 ..........................................FVITLFLALIIRNKPAF..AFM..VIFLGI..L..CSAGI.AYLGYFLIDTKVRSRITSLDNAQFFVYDNS.LSVDYSLTNTSKKSFRYCKLKVEVFKKSDDN.......................sTFKNLIHTIKPLRSKSTMIEKTINPQ.QTINLKTKFSDFKE..GQNFD...IEISSKCF............
B9L6F7_NAUPA/20-183                 ..........................................FIFLVIISIKAAGNSTK.lLLS..MIFASF..L..VTAFG.AGLGLVILEKYTKKAKLINVKQRRVLINET.LVLKGRVKNIGKFKINYCKLEIKLVNNGWGGkftkgsff.......kpgglsifgSKDKQQAKPNTVKATRIIIKDGLLPG.EVKDFSAIIPYPPY..FKNTY...LNYKLYCH............
E8V8M3_TERSS/63-169                 ....................................sltfen-----------------..---..------..-..-----.----------------ITLSEAGHGTGTKS.IYVDGQLKNNGSRTLSALTVQAIFHAADGSNaa...................letLPLALVRSREPYVDLQPISAAPVAPG.ASADFRLIFEGIPD..AWDQ-...--------qppqira.....
J1F8M3_9HELI/27-177                 .......................................ffa--LIFALVIS-AKKPTL..SGF..MLLLVI..L..AVFVG.PFFTYFKIHDYLYGTDVKLTYIKQMKFADV.LLLRGTLTSRGEERIDKCRLHTFVVPPQEGF.......................kESLEPVFLLKPLKKKSLVFETELNKGdTSKEFIIKFTNFKH..SKEINsshIYIYPEC-f...........
E8X3Y1_GRATM/63-170                 ....................................aslpit-----------------..---..------..-..-----.---------------GIVMSESTSLSGGKS.TFIDGHIRNTGNRTISSATVQVLFANDAQLPpq...................letLPLAVIRTHEPYVDTQPLSDAPLKPG.DDREFRLIFENINS..NWNQQ...--------lpeihv......
C1F7T9_ACIC5/67-209                 .........................................l-VIVGLIGFYNFSQKAK..---..--ILPN..G..EAALA.PYASHLTISNV-------QLSQAGSMVGTA.TYIDGTITNTGRKTVTGVTVQAVFHDFDHKTtq...................vsnLSLNLIRTRVPYVDTEPVSSAPIQPG.KSAEFRLIADQMSD..SWDQS...--------ppelrivqvdtq
E4TXY0_SULKY/15-176                 .........................................l-ILLLLIGFLVSLRTN-..SKF..SVFTTI..S..LTLMLiGFFTWRSINENVYIVEVSQLDQERFYQSEQ.IVLKGIVRNVGNYPVANVIATVKLINSHGGVggkqslftqps..vfaqiyegdnpNFKRQT------VEKEELVADYLNPG.KAKPFTIIMKYPSY..FKHAT...FDVTAKA-a...........
E4TXY1_SULKY/27-171                 ..........................................FLLFLVLAIALRHKMAL..AVL..FVVLAF..G..TLTAG.SVAGYIQLHKYLFKNKIILHEVKALQYTEA.LLIKGDINNTSKRSFKECTITTGVYKVTHNK........................-YLDRVYPYVPFKKSSQKFIKPIPPG.ESKPFKLFVEPFRY..TKDYN...ITIKAEC-r...........
B9D5P9_CAMRE/31-175                 ..........................................FLALVSLCVYVASKSYL.aGFA..LVIVTI..A..GLGCG.AYFMPKLLDENLRTRSLELVSTKQLEYSNT.LLVDLRLTNLSKKSFNYCKIGLSFYKNSGNA........................-LRRYANELKPFLKENIVLKDALDVN.ATHEITHAVNNFRA..-QDYN...VTASSECF............
D1AZ76_SULD5/19-178                 .........................................s-ILIVLLTLKNTERKAL..-FA..PIMANL..L..ITSLL.IAFTFYALDKYTKIARLENMVQKKVLINES.FSISGQIRNVGKFTIGKCKLEVKIFNASLERigtdsai.........fvpksafeNFFKRDQLPTIETTKTFLIAENLTEG.EMRNFTVFMPYPPA..FEKPY...TRYELFCH............
A7GWD4_CAMC5/5-183                  ........................yftivhiivmlvifllsm--LLLVLSMRAERKLFW..--S..LLFINI..L..VSTTL.CVFLMLVLDKYTKKGSLENVTSERILINES.IAFKGKVRNVGNFTLTHCTLSVRLVNRPQNRdghfkeifkp....sgltffsslfKSEDKDEKPN-AVEYKFDVAQNLQKQ.RSVDFMVSMPYPPY..FENVM...HITKLSCY............
Q7MSU8_WOLSU/33-177                 ..........................................FILFFVLGILIKDRGGW..AFL..PIGIAF..S..LLGSS.PWIVEMAMKKVFHPIEINLGFNQRLSFTEA.FFVDGVITNQSSRTFRGCVVTIKLAPPSSKP........................-MDEIRYRLKPLVVKKETILRPLFPR.ESLTFQYTVDNLNY..EGALT...SKIEASCF............
C6RHS4_9PROT/31-175                 ..........................................FLALVSLCIYVASKSFF.aGFA..LMIVTI..A..GLGCG.AYFMPKLLDENLRTRSLELVSTKQLEYSNT.LLVDLRLTNLSKKPFNYCEIGLSFYKNSGNT........................-LRRYANELKPFLRENIVLKDALDIN.ATREITHVVNNFRA..-QDYN...VTTSSECF............
I7GZ81_9HELI/31-176                 ..........................................FIMLFTLGLLLRGRRFI..ARF..FFFLSI..I..TILAA.PFVLHFVMKNVLYKIDVTLMSAYPMQYTKG.FFVAGNITNKGRAPINECLISVDSVRDEKDS........................KFMRYFNSIFPKSSLSTSIDIDIEPD.NNADFSVIVPNFEA..QEPLL...FRVYVDCY............
E7AD80_HELFC/33-174                 ..........................................FILLFCIGIVLRGVA--..SAF..LYVLSF..L..VLFGA.PFVVRYATEAYFYKIQTTIEHAAALVYTPA.FAAQIKIKNEGHLPLKKCVLRLDVQQSFHNK........................-FQEILSHIISAKTYFKTFETTLERQ.KETHFNWSIDSYPY..-RNHA...FKLTANCY............
Q0PBN9_CAMJE/19-169                 .........................................a-LICILIFLKVKQKEM-..ALI..SYTIAT..I..FTALL.IYSIFLTINQFTTQADLSKLTYTRDLRHES.VIVSGKVQNLTKFEIKKCYLILSILNQQQVGgei..................fndKNIRNAKMQNTSVSYTIEIIDTLPGN.TYKEFRASVPFPPT..FNNPE...FYHTLKC-i...........
C6RHS3_9PROT/9-177                  .............................hfiaiavlallsm-----LFALISRGEKNP..KFFkiYIAINV..I..ATLTL.GYFFMMIVDKYTKKAVLTEFSGHRVLRNET.IVFKGLLRNTGEFSIANCDLTVKLINNPVSKdtiagsi.........fkpsglslS--SRSDERSNVAEITASVAKNIAPK.QIRNFSLSMPYPSY..FANTQ...TITKLEC-r...........
F8KR33_HELBC/34-175                 ..........................................FLCFFIAGLVVRGYT--..ATF..LYLLSF..V..CLFGA.PFGVHYLLEQQLFKIHTKVEQAYAFTYTDA.FEARVQITNEGRMTIRQCALRLDVLKPASNK........................-PQEFLYQWLFEHTYIQTFKVVLAPK.QTHSFNLSIEHYPY..-KQTP...FKLSSACY............
B9D5Q0_CAMRE/8-177                  ..............................fhlialavlvll---SMLFMLISRGEKDL..RLF..KIYLAInvA..ATLIF.GYFFMLVVDKYTKKAVLIEVTGHRVLRNEM.IVFKGSLRNTGEFSIASCELTVKLVNNPVSKdtiagsi..........fkpsglsLFSRGDERSN-VAEVTASVAKNIAPK.QIRNFSVSMPYPSY..FTNTQ...TITKLEC-r...........
D1AZ77_SULD5/32-179                 ..........................................FLILIFLAILVAKKSSA.fALL..IIIVSL..L..FLGIA.PFFIYQKLNTTLRKTETTITLLKKLNFSSS.LILETTITNQSKKDFNLCILHASIFKADENI.......................sNIKAYLYQLKPLANQSIIIKEFIPQE.STLEYRIVFDDFDY..SGDIN...ATLKAECY............
A7GWD5_CAMC5/31-176                 ..........................................FIFILFLGIFFALKSWWqiGFL..FIMADL..F..ALLAG.FYYANDALSQNLRPVEISAVNTKQLTYSNA.LMIDFNVTNRSKKMLNVCKIDLGFYTVSKQK........................-SRDFLNSLNPFAKKTIVLREPFIPG.EVKQIKDFVNEF-S..FIDYN...ITKKAECF............
Q30PD3_SULDN/26-169                 ..........................................FLILLIIGIVFRQKTLL..AVF..LIFFAF..I..ILIFG.STVGYVEMHNYLFKNETTLTSQKKLSFTQA.VVVYGRVKNVSQRDFKSCKVSATVYRFSGNE........................-IKDYIKKFKPIVKMS-IVEEDIAIG.QEREIKIIISPFVY..GGDYN...VSLGADC-r...........
A0RMS0_CAMFF/3-146                  .........................................l-VVLFLVIILIFKRPGL..ASI..LLIADI..V..FVFLG.IFYTHKFIDETLRKREIMISDIKQLNYSDT.MIVDLNLTNKSNKAFKYCNVNLKFYKVAPNK........................-FKNYINSLKPFYKKNSVIEDGVNIG.QTKNLRLVINDFRP..-TDYN...TTVTSECF............
K4RIZ1_HELHE/37-178                 ..........................................FLCFYIPGLLFRGLV--..SSF..FYILAT..L..CILGT.PFTVRYLLEEQLFKIQTDIREAFSLTYTNA.FMAKVHVKNVGHLAINQCILRLDILHPSYNK........................-FQEYLHKWVFAHTYTQSFKVQIPPK.QAKDLVMDIENYPY..-KQAP...FKLSADCY............
C3XMM2_9HELI/32-177                 ........................................ii-LLIFLLSVALRGRAL-..-PF..MLFFSL..SggLILAS.PFIYQWIMESYLKKIEFTLTHNASLQYDAV.YFVEGSFKNLGHLDFRGCVVEVNFIPKDLKK........................-FERIKYKINPKYSKTEIYKTPLKKQ.EAMDFKIVIPSPNS..QVQFD...LDTKGACY............
Q1IVJ8_KORVE/24-169                 pmivgallvivvvaaiaffnrnsnkgqvqhdpyadklpisdm-----------------..---..------..-..-----.------------------QMSKSENYVGAAvTYVDFTVTNTGDKTVTGAQVQVTFRDSLNQSvgs.................etlaASVLIPNTLGGYPDVTDLTRAPLAPG.KSRTIRLTFEHVSA..EWNQN...Y-------pevklvn.....
Q7VJ04_HELHP/1-119                  .........................................m-----------------..---..------..-..-IFST.PVVLQFVMQRVLYPIDVNITSAHAMQYTKG.FFVAGHITHKGKIAINECYIAVNEVRDEKNN........................KVLQVLNTIIPKSSSGTTISIDIGVG.ESNDFAVIVPNFEA..KEPFL...YRIYVDCY............
I3ZJQ2_TERRK/25-171                 ..iiaavavlvivavaaiatlrrapantgaalapdayaaslp-----------------..---..------..-..-----.-------------ITNISMSEATNGTGGKA.TYVDGVIGNTGTKTLTGAEVQVTFSTSDGTAph...................retVPVAVVRTRVPYVDLQPLSADPIKPG.DHRDFRLIFESVPA..NWDV-...--------qppaiqvvrt..
E0UQN0_SULAO/14-182                 .................................liflmlvgg----IIAALKQTNKKL-..AYS..MIFSIT..L..VAVFM.AVFSVIIVDKYTKKVQLSKLHNKRLLSTEE.ISYYGIVKNIGKLPIGKVTFEIKLVNKGHATgnvkggnfyk....asgfmnffsgGFGMLSHKPQT-ITKKFVVARNLKPG.QAKDFRVYFRYPPY..FRSTA...--------efskvygh....
B6BI06_SULGG/11-181                 ..............................iilaiilfifig---GVVSAFKQTNKKLV..-FP..MLISVS..L..ITALM.AGFSIVVVDKYTKIPKIYKLENKRLLSIEK.IVYTGIVKNEGNHEIGTVTIEIKLVNKGHATgnvkggnfy.....kpsgfldffsGGADILYKPQTIVK-EFVVATNLKPG.EAKAFRVYFGWPPY..FRSVA...--------efvkimg.....
O25031_HELPY/36-179                 .........................................c-AILLLLALLLRNRL--..ASY..IATAAF..L..GAFLSmPFVLNILLTQAIYPIETRILHANPLSYSNA.FSLQVGVKNHSKFTLNKCVLRLEVLKNPHNF........................-VEEHAFKWFVKKSYEKIFKEKILPK.ESKVFSFFIDNYPY..SKTAP...YQVSLFC-l...........
D3UJ86_HELM1/27-168                 .........................................s-LLFLLVGIALFKRRFF..PSF..FFLLSL..L..SLFSA.PFFIAYGSKKFLFKTTILHNQSRPLMFSDS.FLIHLSFRNDGYRKIKHCMITISPKREKNLR........................--NQLLDIFKPLERSYYVFSADISPH.AAKQIQTIIPYF--..MREHA...FKLILDC-r...........
G8NVX1_GRAMM/27-175                 ......ttavgiasvavvilvlvlvmlghrhgsssaanaayg-----------------..---..------..-..-----.---------PNLAISNIQMSESTSISGGKS.TYIDGHIANHGPSTVTGVTVQVLFANDTGMPpq...................tetVPLSLIRTREPYIDTEPVSAAPLAPG.AEADFRLIFEGIND..NWNQQ...--------kpeihatqvst.
C5ZY05_9HELI/34-180                 .........................................i-LLFFLLSILLSSNTIV..CFL..MLFMSA..I..LFFAS.PFIYQYIMQTYLKKIELTLSHNSKLQYDDI.YYIKGTIKNAGSLDLKGCVVTTNFIPKNSNQ........................-FQQIKYTIRPIFRHKETYKKPLKKQ.ESFEFEALFEAPKSliYSNYK...LQTQADCY............
#=GC seq_cons                       ...........................................hhhhhlulhhptcthh..thh..hhhhsh..h..hhhhh.shhhhhhlcphhhphplphhpspplphscu.hhlcGplpNpGchslspCplplplhpsspsp.........................htchhpphpshhshp.hhppsltss.ps+sFplhhs.hsh...pshs...h.hphpC.............
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