#=GF ID   DUF2420
#=GF AC   PF10336.4
#=GF DE   Protein of unknown function (DUF2420)
#=GF AU   Wood V, Coggill PC
#=GF SE   Pfam-B_32350 (release 21.0)
#=GF GA   21.00 21.00;
#=GF TC   22.00 21.00;
#=GF NC   20.50 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR018822;
#=GF CC   This is a family of proteins conserved in fungi.  The function
#=GF CC   is not known.
#=GF SQ   112
#=GS A7TQ20_VANPO/105-218  AC A7TQ20.1
#=GS F0UFQ8_AJEC8/347-452  AC F0UFQ8.1
#=GS C5M6X9_CANTT/307-419  AC C5M6X9.1
#=GS A8Q9N2_MALGO/82-183   AC A8Q9N2.1
#=GS G4TUV0_PIRID/329-436  AC G4TUV0.1
#=GS E3S3S0_PYRTT/454-560  AC E3S3S0.1
#=GS G7EB53_MIXOS/429-528  AC G7EB53.1
#=GS Q6BM55_DEBHA/387-500  AC Q6BM55.1
#=GS H0EYX1_GLAL7/173-253  AC H0EYX1.1
#=GS C8Z808_YEAS8/82-195   AC C8Z808.1
#=GS H2B158_KAZAF/71-184   AC H2B158.1
#=GS C5P8A3_COCP7/350-455  AC C5P8A3.1
#=GS D4DJ82_TRIVH/292-395  AC D4DJ82.1
#=GS G9NQB7_HYPAI/325-428  AC G9NQB7.1
#=GS C7YZ09_NECH7/336-442  AC C7YZ09.1
#=GS F9X297_MYCGM/302-411  AC F9X297.1
#=GS G3JPP4_CORMM/272-376  AC G3JPP4.1
#=GS Q2UQT3_ASPOR/335-430  AC Q2UQT3.1
#=GS E4V275_ARTGP/293-396  AC E4V275.1
#=GS E7QEE2_YEASZ/86-199   AC E7QEE2.1
#=GS I1RN69_GIBZE/344-394  AC I1RN69.1
#=GS E9D3X0_COCPS/350-455  AC E9D3X0.1
#=GS Q55XR6_CRYNB/297-400  AC Q55XR6.1
#=GS A6SBE3_BOTFB/319-423  AC A6SBE3.1
#=GS C4Y4N6_CLAL4/277-389  AC C4Y4N6.1
#=GS F8P524_SERL9/351-452  AC F8P524.1
#=GS Q5KM73_CRYNJ/297-400  AC Q5KM73.1
#=GS C1GHC0_PARBD/338-443  AC C1GHC0.1
#=GS E7LU45_YEASV/86-199   AC E7LU45.1
#=GS Q4WRL7_ASPFU/323-428  AC Q4WRL7.1
#=GS F9G260_FUSOF/358-464  AC F9G260.1
#=GS E7A0V4_SPORE/264-362  AC E7A0V4.1
#=GS H8WZN2_9ASCO/364-472  AC H8WZN2.1
#=GS E7Q3K1_YEASB/86-199   AC E7Q3K1.1
#=GS C4R2U5_PICPG/201-309  AC C4R2U5.1
#=GS E9EEQ1_METAQ/270-376  AC E9EEQ1.1
#=GS E7KC81_YEASA/86-199   AC E7KC81.1
#=GS G3AL04_SPAPN/270-382  AC G3AL04.1
#=GS G0T0V3_RHOG2/346-443  AC G0T0V3.1
#=GS Q753N6_ASHGO/104-217  AC Q753N6.2
#=GS C0NEL9_AJECG/350-455  AC C0NEL9.1
#=GS G8ZUD5_TORDC/89-202   AC G8ZUD5.1
#=GS H0GUG0_9SACH/1-101    AC H0GUG0.1
#=GS C5GME1_AJEDR/344-449  AC C5GME1.1
#=GS B6QBT8_PENMQ/302-407  AC B6QBT8.1
#=GS G2WDL0_YEASK/82-195   AC G2WDL0.1
#=GS Q4PAZ7_USTMA/262-362  AC Q4PAZ7.1
#=GS Q6CR68_KLULA/128-241  AC Q6CR68.1
#=GS A6ZTU1_YEAS7/82-195   AC A6ZTU1.1
#=GS H0GFY1_9SACH/82-195   AC H0GFY1.1
#=GS A8NG19_COPC7/354-457  AC A8NG19.2
#=GS RMR1_YEAST/82-195     AC P53060.2
#=GS B0D3X4_LACBS/380-482  AC B0D3X4.1
#=GS A1CNM3_ASPCL/316-421  AC A1CNM3.1
#=GS C0SEE9_PARBP/338-443  AC C0SEE9.1
#=GS G0VF26_NAUCC/109-222  AC G0VF26.1
#=GS E3QCA2_COLGM/397-504  AC E3QCA2.1
#=GS Q0V231_PHANO/284-390  AC Q0V231.1
#=GS G8YA29_PICSO/246-360  AC G8YA29.1
#=GS G4MP13_MAGO7/340-445  AC G4MP13.1
#=GS B8M1Z4_TALSN/292-397  AC B8M1Z4.1
#=GS C1H3H0_PARBA/338-443  AC C1H3H0.1
#=GS B6HA01_PENCW/303-408  AC B6HA01.1
#=GS B0XNJ8_ASPFC/323-428  AC B0XNJ8.1
#=GS H1VGL8_COLHI/403-507  AC H1VGL8.1
#=GS G8B7C7_CANPC/373-481  AC G8B7C7.1
#=GS D4B0Z5_ARTBC/292-395  AC D4B0Z5.1
#=GS G0WGI6_NAUDC/108-221  AC G0WGI6.1
#=GS B5VI93_YEAS6/86-199   AC B5VI93.1
#=GS F0XCQ7_GROCL/189-296  AC F0XCQ7.1
#=GS G2YGL7_BOTF4/319-423  AC G2YGL7.1
#=GS B2WK14_PYRTR/462-568  AC B2WK14.1
#=GS E7KN49_YEASL/86-199   AC E7KN49.1
#=GS C6HNI5_AJECH/347-452  AC C6HNI5.1
#=GS A1D1H2_NEOFI/324-427  AC A1D1H2.1
#=GS C7GNZ6_YEAS2/82-195   AC C7GNZ6.1
#=GS B3LHU2_YEAS1/82-195   AC B3LHU2.1
#=GS Q6FRL5_CANGA/126-239  AC Q6FRL5.1
#=GS RMR1_SCHPO/230-332    AC O94577.3
#=GS E3KVD3_PUCGT/76-166   AC E3KVD3.1
#=GS G8BWD3_TETPH/114-227  AC G8BWD3.1
#=GS B6K2L6_SCHJY/193-296  AC B6K2L6.1
#=GS G3XS76_ASPNA/355-460  AC G3XS76.1
#=GS C4JIB9_UNCRE/332-437  AC C4JIB9.1
#=GS F2TB77_AJEDA/344-449  AC F2TB77.1
#=GS F2Q4Y0_TRIEC/292-395  AC F2Q4Y0.1
#=GS E7R4F7_PICAD/197-301  AC E7R4F7.1
#=GS E4ZS34_LEPMJ/340-446  AC E4ZS34.1
#=GS C5JY82_AJEDS/344-449  AC C5JY82.1
#=GS A5DDW2_PICGU/312-422  AC A5DDW2.2
#=GS E6R0S3_CRYGW/300-403  AC E6R0S3.1
#=GS G3BAU6_CANTC/163-275  AC G3BAU6.1
#=GS G8JUT4_ERECY/117-230  AC G8JUT4.1
#=GS G7XIR5_ASPKW/349-454  AC G7XIR5.1
#=GS F8Q6C9_SERL3/351-452  AC F8Q6C9.1
#=GS G7EB52_MIXOS/429-528  AC G7EB52.1
#=GS Q6CB76_YARLI/544-650  AC Q6CB76.1
#=GS C5DLG3_LACTC/161-274  AC C5DLG3.1
#=GS A6QXZ5_AJECN/349-454  AC A6QXZ5.1
#=GS G0R9F4_HYPJQ/334-440  AC G0R9F4.1
#=GS G9MWB9_HYPVG/328-434  AC G9MWB9.1
#=GS C5E4Y7_ZYGRC/99-212   AC C5E4Y7.1
#=GS H6C0J8_EXODN/329-434  AC H6C0J8.1
#=GS F2RWP6_TRIT1/292-395  AC F2RWP6.1
#=GS F2SZU7_TRIRC/274-377  AC F2SZU7.1
#=GS A2QB82_ASPNC/368-473  AC A2QB82.1
#=GS F4RHE0_MELLP/364-461  AC F4RHE0.1
#=GS A5DX68_LODEL/492-600  AC A5DX68.1
#=GS G1XJG4_ARTOA/513-618  AC G1XJG4.1
#=GS B8MZ65_ASPFN/335-430  AC B8MZ65.1
#=GS F2QQY2_PICP7/201-309  AC F2QQY2.1
#=GS C9SUZ0_VERA1/330-437  AC C9SUZ0.1
A7TQ20_VANPO/105-218             ....................aIVCEDESMLHQNCGTLMKVLREFMENYYGKLH.FVTK....ELMMEIPCLE.LTLCE..DN...I..YNE..KITFNDILSIFEILRERSIERGENGIPDHLNVQIA.VRPRFVSRYNSLVELTESDAS...................
F0UFQ8_AJEC8/347-452             ..................tff--LQDEGVANAPIKELVGACRQVL----GEHV.SEDE....ELILDIETLG.LHLPE..CS...G..SEI..TTSLSQIIQVYLELCSNDGISE----PEPLYLTLS.SRSTFTSGFARLVAAAHEGR-g..................
C5M6X9_CANTT/307-419             ....................hCIYENEDYLQKSIEEFFASLREDQQLNEVEPF.LISE....EIILTIPQFEnLKMTE..DN...L..YCR..DISIGDFVSLFRRLSD--STKNKTKIPKQLTFELT.TQPRFITKYNALVDNSQDS--tn.................
A8Q9N2_MALGO/82-183              .................pelh---IDPGVFWEPLDSLFAALRVTD--ALGEFL.EEGT....ELCLAFPDLE.LVLHE..DN...V..YAR..EISLHDISQLALGF----------GYHGSLHVLVT.ETPRFISQYNALAMMMSG---aad................
G4TUV0_PIRID/329-436             ................tlldq----HHHLFAEPIATMLMELRKELQNAEPAIF.SRSEfeyrEFQLVVRDLQ.LVLTE..DN...I..YAH..KITLSDLVSMHQSC----------GLSGYLHLDIS.LQSRFIDRYNVIKQAIENHA-n..................
E3S3S0_PYRTT/454-560             ....................dWLIEDASLAKASMSDLMRACRYSL----GDDV.SNEM....EIGFRFDHFLnMELFE..DN...T..ACV..AVSLERLVNYYHMLYANDGNNE----PESFYITLL.FRPRFATLLSDIAKFADQG--lg.................
G7EB53_MIXOS/429-528             .................vllg---ESHELYYNQLENLITELHIHFE----FFY.DEQL....EMTICIDDLD.IQIPE..DN...V..YTR..ELSLYDLERLHRGC----------DLPGRLRLTIA.ESPRLVFRFNTLADYMANS--lg.................
Q6BM55_DEBHA/387-500             ....................vSLYDDNEILKLTIEEFFGLMRTNEDLNEIHQF.TVNK....ELVLVIPELN.LSITE..DN...I..YSR..DITIEDFIVSFENLNSNSINDGEELIHKSLSFLLT.SQTRFITNFNNLTESIRRGK-g..................
H0EYX1_GLAL7/173-253             ..................sff--LSDLEIIGRPLSEFLLSIREVLS----DEL.QDED....ELCMAVGDLG.LEFEE..TS...I..HCQ..DYTLSQVIDVFHKLEEGG-----------------.---------------------sqedirddt..........
C8Z808_YEAS8/82-195              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
H2B158_KAZAF/71-184              ....................tVMLEDPKLSNTPCNTLMSQIRSFLERHYNKLM.FNSK....EILLDIPVLD.ITINE..DN...I..YNN..QISFADIQTIFKILKERSENNHEMELPECLEATIT.LKPRFVSRYNALVELTESSA-t..................
C5P8A3_COCP7/350-455             ...................my-LLEDEELAHAPLYQLFQAFRKVL----GNNV.SDED....ELVASIDCLY.IQLSE..VA...T..QSS..EINLSQIVQLYLDLSRNDGVDN----PEPLYICLS.SRPILDAELAALQAAVDQGK-g..................
D4DJ82_TRIVH/292-395             ..................tyf--LEDEALADEPIGDLLNACRVVL----GDHM.GTEE....ELYMEIECLG.LHLTE..--...A..VHP..PISLSQIVQVYLDLCRNDGDTN----PGPLYITLA.TQPSFTQNFNTLSEAAQSGK-g..................
G9NQB7_HYPAI/325-428             ...................gf--FSDLSVLDHSMESVLVGLRSELENE----I.AAQD....ELVFQVDELG.LEFAE..AT...AhdALT..TITLRQVLEVFDLLVKNQDPDSSRTLYTYLFTRSS.ASKRF----------------eflsesaaa..........
C7YZ09_NECH7/336-442             ...................gf--FTDTSILDETLEKLLAGLRSELENE----I.TEED....ELVFQVDELG.LELAE..ST...QgeLMT..NVTFRQIIEIFDLLVKNQDPDG----SKTLYTYLF.TKPNTERRLESLI--------esatagkg...........
F9X297_MYCGM/302-411             ...................tg-LLKDDNLASLSLSNLMANCRQRLEYKIGESI.SADQ....DLVLSVQNMG.LIVGE..NS...P..YAF..QTSLSEILEVYIQLHQNDGTST---IP-PLALSLS.LQLKFSSSFNLFKVAAQQG--qg.................
G3JPP4_CORMM/272-376             ..................eaf--FSESSILDDTMQSIFMGFRSQLK----HEV.TAED....ELVFQIDELG.LEFTE..SN...P..-SF..SLTMHQILDVFELLTKNDDPDG----RRTLYTYLF.TRVNNAKRYEYLVESATSGK-g..................
Q2UQT3_ASPOR/335-430             ..................tff--LEDENLAYAPLGELFQSCRQVLQDN----V.GDNE....VLIMDVDALN.IQLTE..DS...L..HIS..KVTLYQIVDLYLQLCHNDGIDEPEPLYLTLNTK--.---------------------ltisaevsd..........
E4V275_ARTGP/293-396             ..................tyf--LEDEALAHEPIGDLLNACRVVL----GDHM.GTEE....ELYMDIECLG.IHLTE..--...A..TRS..PISLSQVVQVYLDLCRNDGDTN----PGPLYITLA.TQPSFTQNFTNLSEAAQSGK-g..................
E7QEE2_YEASZ/86-199              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
I1RN69_GIBZE/344-394             ...................ns-FFADTSVLDQPLEELLAGLRTELENE----V.ATDD....DLVLQVDELG.LEISE..--...-..---..-----------------------------------.---------------------vrd................
E9D3X0_COCPS/350-455             ...................my-LLEDEELAHAPLYQLFQAFRKVL----GNNM.SDED....ELVASIDCLY.IQLSE..VA...T..QSS..EINLSQIVQLYLDLSRNDGVDN----PEPLYICLS.SRPILDAELAALQAAVDQGK-g..................
Q55XR6_CRYNB/297-400             ....................wLKNRQLELAEASLADVWGAIRAECAKE-GLIN.SAGD....GMVITEKLMD.LKMSE..DD...V..NLQ..SITFLELMNLYHGC----------DLPEPVQLHLSwESSRFITRFNAIQSELEAAR-s..................
A6SBE3_BOTFB/319-423             ...................df-FFEDSSVVEKSLNEFCSEIRKVLAE---ENL.PQDD....KISLVIEELQ.LVIEE..TQ...LtsYPP..DLSLGQIIRLYEQLVNNDGAGEIPPLNLRLVIQPT.GPDRFL---------------altkgaa............
C4Y4N6_CLAL4/277-389             ................islft----LDEVVNCTLSEFFKLLRGNGDLIDAYDF.NKED....ELCLRIPELS.LLVTE..DN...V..HTG..DLKLKDLMDTYFSLISRDKKDD-KDTPDKMTILVS.MQPRFITNYKRILDAAI----sgkr...............
F8P524_SERL9/351-452             ...............llhhrp------TLYYEPLTNVFEAFRQEDL--VAQIPdVLEG....ELVLDAYDLQ.LTISE..DN...V..YAR..EVTLHDLNVLHDGS----------DITGPLRIQLRvAAPRFILRYHLLQDQIA----rin................
Q5KM73_CRYNJ/297-400             ....................wLKNRQLELAEASLADVWGAIRAECAKE-GLIN.SAGD....GMVITEKLMD.LKMSE..DD...V..NLQ..SITFLELMNLYHGC----------DLPEPVQLHLSwESSRFITRFNAIQSELEAAR-s..................
C1GHC0_PARBD/338-443             ..................tff--LRDEGLAYAPIGELVEACRQVL----GEHI.SKDE....ELIVDIESLG.LHLPE..YS...A..GRT..TPSLVQIIQVYLDLCANDGINE----PEPLYLTLS.SRSNFMSDYSRLVAAAHEGK-g..................
E7LU45_YEASV/86-199              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
Q4WRL7_ASPFU/323-428             ..................tff--LEDESLAYEPLGKLFESCREVLY----EHV.GENE....TLVLDIESLN.LQLME..DS...T..HIS..KVTLHQIIDVYLRLCHNDGIES----PEPLYLTLS.TKST-----------------isaevsnlllaasegkg..
F9G260_FUSOF/358-464             ...................gf--FANTSVLDEPLEKLIAGLRSELENE----I.AEDD....DLVLQVDELG.LELVE..TT...QgeTMS..NVTLRQILEIFDLLVK----NQDPDGSRPLYAYLF.TKPNAEKRFEYLVESATAG--kg.................
E7A0V4_SPORE/264-362             .................levv-----KDVLWQPLDSLFASLRD--KKALGDFL.DEAH....ELHIAFPDLD.LDVAE..DN...L..YCR..EITLDDLFQLHHGL----------GLATSLHIHVS.ERPRFITKYNELAQHVA----gil................
H8WZN2_9ASCO/364-472             ...................rp-IFEDEKSEDITLDEFFAILRTIPE----FNF.ELND....EIILSIPQFGgITVTE..DN...V..YCK..DLQLSDFLDVYYKL--CDCTTQKEKVPKQLDFKLT.TQPRFIMKYNSLVDTVKEK--gg.................
E7Q3K1_YEASB/86-199              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
C4R2U5_PICPG/201-309             ....................aVMFSDITILNQPFNKFFSHLRSFCNSN-SLDY.SPEK....QYCLEMIELD.IKILE..DD...V..HTK..DVTPRDFIELLSRLKENTDKTA----YNMILIKVT.LVPTLLSVYEHLKDMADSG--kr.................
E9EEQ1_METAQ/270-376             ..................gff---SQLSVLDYSLESVLNGLRQELANE----L.PPED....DLVFQVDELG.LEFAE..SSppdI..L-C..NISLRQILEIFDILVKN----QDPESSRPLYTYLF.TRPSAGRRFDFLMESATE---gkg................
E7KC81_YEASA/86-199              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
G3AL04_SPAPN/270-382             ...................va-LYDSAQIQQLSIELFFQFLRSNEDLSEIFKL.TNAD....EILLEIPELEkLEISE..DN...V..YCK..DITIRDFIEIFVRLCEG--TEDQNKIPKSLNFNLR.TKTRFISKFNHLVEVAGE---sgg................
G0T0V3_RHOG2/346-443             .................daar-----HELYYKPLETLFRVVREEIE----ELR.DQGD....ELVVEFDEIG.ISLSE..DN...I..YSR..QVTLFDFDRIHTGC----------QIPGRLHARIY.AQPRFATGFNALAEHIAR---ias................
Q753N6_ASHGO/104-217             ...................gh-MLADGGHMHKSFSELIAAIRAFLEREYGRLE.LATK....ELLLTFPDLD.LCITE..DN...T..YSK..NISMNDIASIFNILRENSLERDEPNIPDHLHIVLT.LCPRFVAKYNDLVELVDSHAS...................
C0NEL9_AJECG/350-455             ..................tff--LQDEGVANAPIKELVGACRQVL----GEHV.SEDE....ELILDIETLG.LHLPE..CS...G..SEI..TTSLSQIIQVYLELCSNDGISE----PEPLYLTLS.SRSTFTSGFARLVAAAHEGR-g..................
G8ZUD5_TORDC/89-202              ....................pIICDDNVELHASCNGLFTAVRKFLEKYYGSLP.FLSK....ELLFDIPCLD.ITLCE..DN...A..YNN..QITFEDITTIFRILKERSEANSEANVPAHMEIEIS.VRPRFVSRYNALVELTQSTAS...................
H0GUG0_9SACH/1-101               .....................------------MGEFMESIRQFMGSRYGSLA.FATK....ELVLRLRSLD.LTLFE..DN...V..YNN..HISFNDVYTIFKILKERSESDFETDIPTHLAIELT.TRPRFVSRYNALVELTESSA-t..................
C5GME1_AJEDR/344-449             ..................tff--LQDEGLANAPVAELVGACRQVL----GEHI.SEDE....ELILDIESLG.LHLPE..NS...V..PII..TTSLVQIIQVYLDLCSNDGINE----PEPLYITLS.SRPTFTAEFARLAASANEGK-g..................
B6QBT8_PENMQ/302-407             ..................tyf--LADEGLAYENIDRLFKECRAIL----GDHA.SNED....SLVFHIDSLS.IELSE..DN...I..HVS..KFTLSQIVDTYLHLCRNSGIEQ----PEPLYLTLN.TRAHLSSELTALLDAAKEGK-g..................
G2WDL0_YEASK/82-195              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
Q4PAZ7_USTMA/262-362             ...................pa-LQISKDVLWQPLDSLFAGLRE--KNALGDFL.DESH....ELHIAFPDLD.LDVAE..DN...L..YCR..EISLDDLLQLHHGL----------GLPTSLHIQVL.ERPRFITKYNELAQHVA----gll................
Q6CR68_KLULA/128-241             ....................sVVIEDRSLIHMELNYLIAAIRLFLQNKHGALS.LASK....EILLHFPNLD.LLCNE..DN...L..YIK..KMTMDDIISIFKVLRTNSLRNGEENVPSTLRIVAS.LQPRFVSRYNDLVEVMDNNG-s..................
A6ZTU1_YEAS7/82-195              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
H0GFY1_9SACH/82-195              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
A8NG19_COPC7/354-457             ............svmfqdrpm-------LFYEPLPTFFTALRETDVFQQHCDV.LGQA....ELGIFVDSLQ.LSVSE..DN...A..YAQ..DVSLHDLSLLHDSFHT-----G------LLQLQLHmNTPRFAVRYQELQDQLQ----rlv................
RMR1_YEAST/82-195                ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
B0D3X4_LACBS/380-482             ..............vilqhlp------TLYYEPLHSVFEAFRQEE-HLHTLFD.STNA....ELTLDAYELQ.LIVSE..DN...F..YAR..EVTLHDLNILHDA----------AGIHGPLRLRLTaTSPRFIVHYRRLQERVS----npi................
A1CNM3_ASPCL/316-421             ..................tff--LENEALAYESLEKLFESCREVLY----EHI.GENE....VLVFDIESLN.MQIAE..DS...S..HVA..KVTLHQIIDVYLRLCHNDGIDT----PEPLYLTLS.TKL------------------nisaeisdlllaanqgkg.
C0SEE9_PARBP/338-443             ..................tff--LRDEGLAYAPIGELVEACRQVL----GEHI.SKDE....ELIVDIESLG.LHLPE..YS...A..GRT..TPSLVQIIQVYLDLCANDGINE----PEPLYLTLS.SRSNFMSDYSRLVAAAHEGK-g..................
G0VF26_NAUCC/109-222             ....................pIICENTKYNNGSCTELLASVRKFLETYYNRIL.FGSK....EILFEIPALD.LTLCE..DN...I..YNN..QITFSDIETIFRILRERSMANSEEDVPLCLEANIS.TRPRFVSRYNALVELTESTAS...................
E3QCA2_COLGM/397-504             ...................ec-FFHDLSLLHCKMEGVLAGFRRELANELGPF-.---D....ELVFQIDELG.LEFAE..SS...QpdVFS..DITLGQIISVFDSL----VKNQNPNASKPLYAYLS.TRPNCKKRWLSLVDDA-----yngkg..............
Q0V231_PHANO/284-390             ....................dWLTEDTSIIHSSLSEMFQACRASL----GENI.SNET....ELGLRFDHFHnMEIFE..DS...T..ACV..AVSLGRMIDLYYTLHAQDGESE----PESFYMCLL.SRPRFATLLSDIAKHADQGHG...................
G8YA29_PICSO/246-360             ....................vSLYDDQNVLNSSLESFFVSMRNHEDLNEICSF.DASR....ELVLTVPELGnITITE..DN...I..YSR..EVSVNDFVDRFHDFKLNSKLHDSELLFQTLSFKLS.FQTRFISEFNNLSKLLRE---dcg................
G4MP13_MAGO7/340-445             ..................sff--FSDMEALEFPLSQFLASLREVVE-----DV.ANDD....EVLIRIDELG.LEFAEttDK...K..LLD..KITFRNLVDLHDRLVRADDPDS---QHHTMQIFLV.TRP------------------ncqrrlealldganvg...
B8M1Z4_TALSN/292-397             ..................tyf--LANEGLAHENIDRLFKECRTIL----GDHA.SDEE....SLVFHIDSLG.IELSE..DN...T..HVC..KFTLSQIVDTYLHLCRNSGIEQ----PEPLYLTLN.TRANLSSELAALLNAAMQG--kg.................
C1H3H0_PARBA/338-443             ..................tff--LRDEGLAYAPIGELVEACRQVL----GEHV.SKDE....ELIVDIESLG.LHLPE..YS...A..GRT..TPSLIQIIQVYLDLCANDGINE----PEPLYLTLS.LRSNFTSDYSRLVAAAHEGK-g..................
B6HA01_PENCW/303-408             ..................tff--VEDEALAYENIGEIFKALRQVLQ----KTM.AGNE....VLVIDIDTLG.IQITE..DS...F..HTS..QVTLHQILDLYLRLCRNDGTTE----PDALYLTLS.TKRAFPAELADLNDAAI----egkt...............
B0XNJ8_ASPFC/323-428             ..................tff--LEDESLAYEPLGKLFESCREVLY----EHV.GENE....TLVLDIESLN.LQLME..DS...T..HIS..KVTLHQIIDVYLRLCHNDGIES----PEPLYLTLS.TKST-----------------isaevsnlllaasegkg..
H1VGL8_COLHI/403-507             ....................eCFFNDLSLLHCKMEGVLAGFRRELASELGP--.--LD....ELVFQIDELG.LEFAE..SD...V..F-S..DITLGQIISVFDSL----VKNQNPDASKPLYAYLS.TRPNCKKRWLSLVDDA-----yngkg..............
G8B7C7_CANPC/373-481             ...................sa-IFEDEKSEDITLDEFFAILRTISE----FHF.ELDE....EIILSIPQFGgIALTE..DN...V..YCK..DLQLSDFLDVYYKLC--DCTTAKEKVPKQLDFKLS.TQPRFIMKYNSLVDTIKQN--gg.................
D4B0Z5_ARTBC/292-395             ..................tyf--LEDEALADEPIGDLLNACRVVL----GDHM.GTEE....ELYMEIECLG.LHLTE..--...A..VHP..PISLSQIVQVYLDLCRNDGDTN----PGPLYITLA.TQPSFTQNFNTLSEAAQSGK-g..................
G0WGI6_NAUDC/108-221             ....................pIICDNPRFFNTSCTEFMASVRRFLEKYYNGVL.FNSK....EILMDIPALD.LTLCE..DN...L..YNN..QISFNDIETIFRILKERSIANSELRVPAYMEIRIQ.TRPRFVSRYNALVELTEGAA-t..................
B5VI93_YEAS6/86-199              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
F0XCQ7_GROCL/189-296             ..................sff--LEDLEAANYPLSKFLLTIRSGIA----SWV.HAED....EIFIRIDDLG.FEFGE..TT...TeaLLD..QVTFHNLIALHNTL----LTNDDATLSKGLHITLG.TRPNCLLRLKKLVSEAGSGK-g..................
G2YGL7_BOTF4/319-423             ...................df-FFEDSSVVEKSLNEFCSEIRKVLAE---ENL.PQDD....KISLVIEELQ.LVIEE..TQ...LtsYPP..DLSLGQIIRLYEQLVNNDGAGEIPPLNLRLVIQPT.GPDRFL---------------altkgaa............
B2WK14_PYRTR/462-568             ....................dWLIEDVSLAKASMSDLMRACRYSI----GDDV.SNEM....EIGFRFDHFLnMELYE..DN...T..ACV..AVSLERLVNYYHTLYANDGNNE----PESFYITLL.FRPRFATLLSDIAKFADQG--lg.................
E7KN49_YEASL/86-199              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
C6HNI5_AJECH/347-452             ..................tff--LQDEGVANAPIKELVGACRQVL----GEHV.SEDE....ELILDIETLG.LHLPE..CS...G..SEI..TTSLSQIIQVYLELCSNDGISE----PEPLYLTLS.SRSTFTSGFARLVAAAHEGR-g..................
A1D1H2_NEOFI/324-427             ..................tff--LEDESLAYEPLGKLFESCREVLY----EHV.GENE....ILVLDIESLN.LQLME..DS...T..HVS..KVTLHQIIDVYLRLCHNDGIDS----PEPLCLTLS.TK-------------------ltisaeisdlilaaseg..
C7GNZ6_YEAS2/82-195              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLA.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
B3LHU2_YEAS1/82-195              ....................pIICENAALYQRPMGEFMESIRKFMGNRFGRLT.FATK....ELVLQLKSLD.LTLFE..DN...V..YNN..HISFSDVYTIFKILKERSESNFETDIPTHLAIELS.TRPRFVSRYNALVELTESSA-t..................
Q6FRL5_CANGA/126-239             ....................qCVCKDPAMLQRSFSEFMAHLRSFLESRHGRLK.FASQ....EILLSIVPLD.LVVCE..DN...V..YNS..QISLADVVNIFEILQTRSREAEEREIPKHLDMEVS.TRPRFVSRYNTLVELTEGKA-t..................
RMR1_SCHPO/230-332               ...................yl-YSNGDDLNENTIEDFFGLVRARLESL--NLL.DSDS....ELLCEFPDLS.LKINE..DN...V..YAS..QIHLVDILEILTV---------HCDLEESFSIVFS.TQPRFIARYNELVQAVSSSS-n..................
E3KVD3_PUCGT/76-166              ygplsnfisqglhqifpnlhd--------------------------------.QHKN....EFILHFTNLE.IKVPE..DN...I..YSK..ELSLFDIDRLHIGA----------RLPDRLMISLE.KQPRLVHRFNILANYVA----ele................
G8BWD3_TETPH/114-227             ....................sILCEDVSLVNAECLELLKHIRLSLERYYGKLA.FMSK....EMYLHIPSLD.LTINE..DN...L..YNN..KISMNDIISIYEILRGRSLDRNEANVPDHLLVELK.LRQRFLNRYNSLVELTENDE-a..................
B6K2L6_SCHJY/193-296             ............pilsgdedf-------MESMSLEYLFGILRARLDSL--GLL.ADDV....ELVCSFEGLD.LSMAE..DN...I..YAS..QINLVDMVGLFASQ---SE------PNQVFRIHVA.TQPRFIARYNKLVQRSSRSS-s..................
G3XS76_ASPNA/355-460             ..................tff--LEDESLAFGSFGKLFESCRDVLR----EHI.GDGD....VLVVDVEALN.IQLTE..DS...L..HID..KVTLHQIVDLYLRLCHNDGVEE----PEALYLSLS.TRPTVAAELSSLSIAANEG--kg.................
C4JIB9_UNCRE/332-437             ...................iy-LLEDEELAHAPLYELFKAFRKVL----GTYI.ADED....ELVVSIDSLY.IQLSE..IA...V..KSL..EVTLSQILRLYLDFCRNDDIED----PGPLYLNLS.SRPTLKADLAALQTAADNGQ-g..................
F2TB77_AJEDA/344-449             ..................tff--LQDEGLANAPVAELVGACRQVL----GEHI.SEDE....ELILDIESLG.LHLPE..NS...V..PII..TTSLVQIIQVYLDLCSNDGINE----PEPLYITLS.SRPTFTAEFARLAASANEGK-g..................
F2Q4Y0_TRIEC/292-395             ..................tyf--LENEALADEPIGDLLNACRVVL----GDHM.GTEE....ELYMEIECLG.LHLTE..--...A..VHP..PISLSQIVQVYLDLCRNDGDTN----PGPLYITLA.TQPSFTQNFNTLSEAAQSGK-g..................
E7R4F7_PICAD/197-301             .................tvlf----GEDIFELSLELFFSRLKAK------HRF.KEER....ELILKCSSLGdLTIEE..DN...I..HCS..KVSVGDIVDLFKGLRSQS---DNPDLYKFIQFEVV.TRPRFIMQYERLKSQLESGK-g..................
E4ZS34_LEPMJ/340-446             ....................dWLLDDISLTRSRISDVFQACRASL----GDDV.STEH....EIGFRFDHLHnLELYE..DN...T..ACV..AVSLDKLVDLYHTLQAQDGNNA----PESFYISLL.FRPRFATLLSDIAKFADQG--lg.................
C5JY82_AJEDS/344-449             ..................tff--LQDEGLANAPVAELVGACRQVL----GEHI.SEDE....ELILDIESLG.LHLPE..NS...V..PII..TTSLVQIIQVYLDLCSNDGINE----PEPLYITLS.SRPTFTAEFARLAASANEGK-g..................
A5DDW2_PICGU/312-422             ...................vp-LFDSSSVLELPIEEFFGLMRHNEDLNEIYNF.SVDE....ELVLSFPQFDgLHLTE..DN...V..YSR..EVTFNDFLSTFERLAENTVSEK----PLSMACTLT.SQTRFITKFNGLAELIREKKG...................
E6R0S3_CRYGW/300-403             ....................wLKNRQLELAEASLADVWGAIRAECAKE-GLIQ.SAGD....GLVITEKLMD.LKMFE..DD...V..NLQ..SITFLELMNLYHGC----------DLPEPVQLHLSwESSRFITRFSAIQSELEAA--gs.................
G3BAU6_CANTC/163-275             ....................mALFENTSLLESSIGELFEIIRTDDDLVELHNY.TKMD....ELVLTIPELNgIKISE..DN...I..YTR..NILINDFTKMFNALTYKTASED--LNFSHLNFSIS.VQPRFITDFNALNDSIRRGHG...................
G8JUT4_ERECY/117-230             .................eyil---ENTMDMHKGFNQLISSIREFLQESFGTLE.FATK....EIQINFPDLE.LCVSE..DN...A..YTK..NITMNDIVSIFKILRENSFKRGESEVPSHIHTIIS.LSPRFVSKYNDLVELVDNNAS...................
G7XIR5_ASPKW/349-454             ..................tff--LEDESLAFGSFGKLLGSCREVLR----EHI.GDSE....VLVVDVEALN.IQLTE..DS...L..HID..KVTLHQIVDLYLRLCHNDGVEE----PEALYLSLS.TRPTVAAELSSLSIAANEG--kg.................
F8Q6C9_SERL3/351-452             ...............llhhrp------TLYYEPLTNVFEAFRQEDL--VAQIPdVLEG....ELVLDAYDLQ.LTISE..DN...V..YAR..EVTLHDLNVLHDGS----------DITGPLRIQLRvAAPRFILRYHLLQDQIA----rin................
G7EB52_MIXOS/429-528             .................vllg---ESHELYYNQLENLITELHIHFE----FFY.DEQL....EMTICIDDLD.IQIPE..DN...V..YTR..ELSLYDLERLHRGC----------DLPGRLRLTIA.ESPRLVFRFNTLADYMANS--lg.................
Q6CB76_YARLI/544-650             ..................fed--IRGSELQEYSMEDVFGLMRRSLE----GFC.SMDE....ELVLTCAQLG.LVLGE..DN...V..CSK..DATLMDLVRLFQTFAANTVDYQR---PATFDMRLS.LSQRFISNYNRLYSLAQQGHS...................
C5DLG3_LACTC/161-274             ....................kIICTDSADLHRGCNVAFGRMRLFFQQVHGGLE.LLSK....ELSFEFPDLD.LVMEE..DN...M..YNK..DITVNDVVSIFKIIKDNSIKKCEPDVSNHLTINVS.TKPRFVSRYNSLVEMLNGD--at.................
A6QXZ5_AJECN/349-454             ..................tff--LQDEGVANAPIKELVGACRQVL----GEHV.SEDE....ELILDIETLG.LHLPE..CS...C..GEI..TTSLFQIIQVYLELCSNDGISE----PEPLYLTLS.SRSTFTSGFARLVSAAHEGR-g..................
G0R9F4_HYPJQ/334-440             ...................gf--FSDVSVMDQSMESLLAGFRAELE----DEI.AAHD....ELVFQVDELG.LEFAE..AT...M..QNSiaSITFRQVLEVFDLL----VKNQDPDSSRTLYTYLF.TKPNPSKRFEFLVESAAASK-g..................
G9MWB9_HYPVG/328-434             ...................gf--FSDVSVLDLSMESVLAGFRAELENE----I.AAQD....ELVFQVDELG.LEFAEatEQ...K..SLA..AITLRQVLEVFDLFVKNQDP----DSSRVLYTYLF.TR-------------------snagkrfeflaesaaagrg
C5E4Y7_ZYGRC/99-212              ....................pVICEDTKGFVHGCNELFNLIRRFLEDYHGKLS.FVSK....ELILELPCLD.LTLCE..DN...V..YNS..QITFSDITTIFDILRQRSLENLETDVPECIRGTVS.TRPRFVSRYNTLVELTQSSA-t..................
H6C0J8_EXODN/329-434             ..................myf--LADSSLAFEPLDKLLAACRELLT----GTL.DHHD....ELVLDITSLG.LHICE..DS...K..YAS..QITLAQILDVYLQLCRNDVGQE----IRPLYCYLS.SRVSLASQYAYLVSSSQEGR-t..................
F2RWP6_TRIT1/292-395             ..................tyf--LENEALADEPIGDLLNACRVVL----GDHM.GTEE....ELYMEIECLG.LHLTE..--...A..VHP..PISLSQIVQVYLDLCRNDGDTN----PGPLYITLA.TQPSFTQNFNTLSEAAQSGK-g..................
F2SZU7_TRIRC/274-377             ..................tyf--LEDEALADEPIGDLLNACRVVL----GDHM.GTEE....ELYMEIECLG.LHLTE..--...A..VHP..PISLSQIVQVYLDLCRNDGDTN----PGPLYITLA.TQPSFTQNFNTLSEAAQSGK-g..................
A2QB82_ASPNC/368-473             ..................tff--LEDESLAFGSFGKLFESCRDVLR----EHI.GDGD....VLVVDVEALN.IQLTE..DS...L..HID..KVTLHQIVDLYLRLCHNDGVEE----PEALYLSLS.TRPTVAAELSSLSIAANEG--kg.................
F4RHE0_MELLP/364-461             ...................el---ADQAIYFAPLGDFIETLRQIFP---DFTQ.TDHS....ELVLSFPDLE.ARIPE..DN...V..YTR..ELSLFDIDRLHVGA----------NLPSRLLVSLE.KQPRLIHRFNVLAKHVWK---qn.................
A5DX68_LODEL/492-600             ....................aSLFADNSVANMTIEELFGALRNCEE----FEF.NEEE....ELVLTISQMGgISITE..DN...V..YCK..DVTLESFLDLYYQLSK--FTDLEENIPRHLDFSLT.SQPRFITKFNRLVDNAQDQN-g..................
G1XJG4_ARTOA/513-618             ..................tcf--LPDRSHLGSPLSKLVAALRDVL----GEEF.TSSE....ELILNFTALG.VEFEE..EN...N..QMN..NFTLYDLLGLFSKLLAQDGVEE----ARPLHISLT.SRKKYIPRLEMIHSHIVE---ggg................
B8MZ65_ASPFN/335-430             ..................tff--LEDENLAYAPLGELFQSCRQVLQDN----V.GDNE....VLIMDVDALN.IQLTE..DS...L..HIS..KVTLYQIVDLYLQLCHNDGIDEPEPLYLTLNTK--.---------------------ltisaevsd..........
F2QQY2_PICP7/201-309             ....................aVMFSDITILNQPFNKFFSHLRSFCNSN-SLDY.SPEK....QYCLEMIELD.IKILE..DD...V..HTK..DVTPRDFIELLSRLKENTDKTA----YNMILIKVT.LVPTLLSVYEHLKDMADSG--kr.................
C9SUZ0_VERA1/330-437             ....................dCFFHDLSVLQCKMEELLASLRRVLV----DDV.AESD....ELVLQVEELG.LEFAE..SS...HpdHFS..EITLGSILQVFDHL----VKNKDPEATRPMYALLI.TRPNCSKRWSSLIEDA-----wngkn..............
#=GC seq_cons                    ....................h..hcstulhppslsclhtuhRphlt...sphh.sssc....ELllplcsLs.LplsE..Ds...s..asp..ploLppllplaptLpppst.st....PpsLhlpLo.opPpFhscastLsphspps..s..................
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