GenomeNet

Database: Pfam
Entry: DUF2529
LinkDB: DUF2529
Original site: DUF2529 
#=GF ID   DUF2529
#=GF AC   PF10740.7
#=GF DE   Domain of unknown function (DUF2529)
#=GF AU   Mistry J, Coggill P
#=GF SE   PRODOM_PD099482
#=GF GA   22.30 22.30;
#=GF TC   22.30 22.30;
#=GF NC   22.20 21.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019676;
#=GF CC   This domain is conserved in the Bacillales. The function is not
#=GF CC   known, but given this domains relationship to the SIS domain it
#=GF CC   may carry out a sugar isomerase reaction. Several members are
#=GF CC   annotated as being YWJG, a protein expressed downstream of pyrG,
#=GF CC   a gene encoding for cytidine triphosphate synthetase.
#=GF SQ   56
#=GS B9E8H0_MACCJ/1-161       AC B9E8H0.1
#=GS A0A0M2SZE8_9BACI/1-168   AC A0A0M2SZE8.1
#=GS A0A0N0Z4C9_9BACI/1-169   AC A0A0N0Z4C9.1
#=GS E6TXE0_BACCJ/1-171       AC E6TXE0.1
#=GS Q814T3_BACCR/1-171       AC Q814T3.1
#=GS W1SA40_9BACI/1-168       AC W1SA40.1
#=GS A0A0B4RE02_9BACL/1-159   AC A0A0B4RE02.1
#=GS YWJG_BACSU/1-169         AC P06629.1
#=GS Q5KUG3_GEOKA/1-169       AC Q5KUG3.1
#=GS B7GMI2_ANOFW/7-174       AC B7GMI2.1
#=GS K6DVL1_9BACI/1-172       AC K6DVL1.1
#=GS A0A023CKC5_GEOSE/1-171   AC A0A023CKC5.1
#=GS A0A0B1XY56_9BACI/1-169   AC A0A0B1XY56.1
#=GS A0A0F5I5Y2_9BACI/1-169   AC A0A0F5I5Y2.1
#=GS Q5HM96_STAEQ/1-168       AC Q5HM96.1
#=GS A0A098F3K4_9BACI/1-173   AC A0A098F3K4.1
#=GS C2WEU2_BACCE/1-171       AC C2WEU2.1
#=GS F9DRD4_9BACL/1-168       AC F9DRD4.1
#=GS D5DWJ0_BACMQ/1-172       AC D5DWJ0.1
#=GS D3FPQ2_BACPE/1-169       AC D3FPQ2.1
#=GS A0A0M2PA46_9BACI/1-173   AC A0A0M2PA46.1
#=GS A0A0C2Y9R4_BACBA/1-169   AC A0A0C2Y9R4.1
#=GS A0A060LYG8_9BACI/1-165   AC A0A060LYG8.1
#=GS B9DMD9_STACT/1-168       AC B9DMD9.1
#=GS A0A0B5AQ69_9BACL/35-204  AC A0A0B5AQ69.1
#=GS Q9K6E1_BACHD/1-172       AC Q9K6E1.1
#=GS E5WGS3_9BACI/1-169       AC E5WGS3.1
#=GS A0A0A8JHK3_BACSX/1-168   AC A0A0A8JHK3.1
#=GS A0A094XB60_BACAO/1-174   AC A0A094XB60.1
#=GS Q5WB44_BACSK/1-168       AC Q5WB44.1
#=GS A0A090J5D8_9BACI/1-170   AC A0A090J5D8.1
#=GS Q81JW2_BACAN/1-171       AC Q81JW2.1
#=GS I8IWI6_9BACI/1-169       AC I8IWI6.1
#=GS A7GV87_BACCN/1-171       AC A7GV87.1
#=GS A0A077J9L1_9BACI/1-171   AC A0A077J9L1.1
#=GS E6MD45_STALU/1-168       AC E6MD45.1
#=GS A0A0N0EBF9_9BACI/1-178   AC A0A0N0EBF9.1
#=GS H0DGG7_9STAP/1-168       AC H0DGG7.1
#=GS C5D9P8_GEOSW/1-172       AC C5D9P8.1
#=GS D6Y0U7_BACIE/1-170       AC D6Y0U7.1
#=GS A0A098EHY2_9BACL/1-158   AC A0A098EHY2.1
#=GS F2F763_SOLSS/1-171       AC F2F763.1
#=GS Q2FWD2_STAA8/1-168       AC Q2FWD2.1
#=GS A0A0M8PY35_9BACI/1-169   AC A0A0M8PY35.1
#=GS A6CQ30_9BACI/7-176       AC A6CQ30.1
#=GS A8FIE4_BACP2/1-172       AC A8FIE4.1
#=GS E8SDZ5_STAPH/1-168       AC E8SDZ5.1
#=GS C2X4D0_BACCE/1-171       AC C2X4D0.1
#=GS A0A0H4KPH8_9BACI/1-172   AC A0A0H4KPH8.1
#=GS B1YEL3_EXIS2/1-165       AC B1YEL3.1
#=GS B1YEL3_EXIS2/1-165       DR PDB; 3JX9 A; 1-165;
#=GS B1YEL3_EXIS2/1-165       DR PDB; 3JX9 B; 1-165;
#=GS Q65DT8_BACLD/1-172       AC Q65DT8.1
#=GS A0A0F7HLF8_9STAP/1-166   AC A0A0F7HLF8.1
#=GS I3EBM8_BACMT/1-169       AC I3EBM8.1
#=GS N0B1J3_9BACI/1-177       AC N0B1J3.1
#=GS X2GPC9_9BACI/1-169       AC X2GPC9.1
#=GS U5LIT8_9BACI/1-172       AC U5LIT8.1
B9E8H0_MACCJ/1-161                  ...........................................................................................MFKIFNTQLNGIFKKI-EAQEVEIDIAARLLAQ.A....V.VGQGKIYVKGFG.....DLKHFEDF.....AVE...SKEK..LFDTEKFITES-.................LIDQTDRILVMSDSYDE-DCHEFITMLKEKDIDFVLVCNK.DDRID-.........----VMNFIDLSTPRA..LV..PTE.N.F.S.RIITPHMMAMNFIYYGIYNVMYEML........................................
A0A0M2SZE8_9BACI/1-168              ...........................................................................................MLKMFTTQLSGLFKRLQEQEEFALEDGARLLAQ.A....A.AGQGTIYIYGTG.....EMAAVHLE.....AVH...GAEP..LAGAAVFDAEK-.................-VTSADRVLMFARYSNDPEALAIAQKLADSFIPFAAASTV.VGGDEP........gLEALADVHVDLKLTKG..ML..PDE.T.G.G.RFALPTSMAALFVYYGFKFIIDEML........................................
A0A0N0Z4C9_9BACI/1-169              ...........................................................................................M-KILTTQTIGLLQKIAADEELALEDGARLLAQ.A....A.IGDGRIWLYGIG.....ELDAVVTA.....ALL...GPDP..LPKAKRLEPTAT................dDWQETDRALLFARFSNDAEAIRLAEQLQAHGVDAVAVAAL.VKDEPG.........LADMATVFIDSKLSRP..LV..PTE.D.G.R.RIGMPTIITASFIYYGLRVLLDEIL........................................
E6TXE0_BACCJ/1-171                  ...........................................................................................M-KIFQTQLQGLIRKI-DDYEESFEEATRYIAQ.S....M.ISDGKVYIFGDM.....EMVGIIPQ.....ALN...GVDR..LPGCLEASETS-.................VFTPLDTVLIFSPNKGSKAAAKVADNARGAGGNVIGVFSE.TTENDGdm....qidWTSQCTVSFSTSISHG..LM..PTE.S.G.D.RIGVPHLLVALHFYYALYFTTMEF-m.......................................
Q814T3_BACCR/1-171                  ...........................................................................................MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQ.A....L.VGDGFIYLHGTN.....EMEGVVAE.....ALF...GAEP..MKQAKRLFENGKe...............aEVTSADRVLLISRFSTDEAVVEIAKKLQEEGHSIVGISAL.QEGTES.........LERYTDVHIDTKLLKG..LI..PDD.E.G.N.RYGFPSLIVALFAYHGIKFTIDEML........................................
W1SA40_9BACI/1-168                  ...........................................................................................MLKMFTTQLTGLFKRIEEKGEFSFEDGARLLAQ.A....P.VGDGSIYIFGTK.....EMKAVELE.....AFE...GAEP..FKGVKRITEAE-.................-LSDADRVLIFSRTSADEDAVTVAAELQEKGIPFVAVSTV.IESAEA........dLAEMADVHIDLRLTRG..LL..PDD.F.G.N.RYGYPSSMVALFVYYGLKFTIDEIL........................................
A0A0B4RE02_9BACL/1-159              ..........................................................................................m--DLFTTQLTRLIERLSEEH-EAIESIAAVLAQ.A....A.IAEGTIFTAAFG.....EMKAVTAV.....ALH...SDNP..LQNAAEWSSAS-.................IVTDIDRVFILATNNEG---AELAGRLSDAGIPFAYVAPP.SNDSE-.........---LADAFLALISEET..SL..IQD.G.N.N.ALLVPHALAGLYVYYAVKLRIDKL-l.......................................
YWJG_BACSU/1-169                    ...........................................................................................MLKIFTTQLTGIFSRIQDKESDAIEDGARLLAQ.A....V.ISGHSIYLYGAN.....ELQGVFYE.....ATE...SKEP..FPSVKAFPENAE.................EVTESDRVLMFCSGTGTAEEQELAKELYEKGAGVVCVSPA.AKDSAG.........IEQYCDVHIDSKLKMP..LV..PDE.D.G.T.RYGFPSLMTALYVYHALSFTLKEIL........................................
Q5KUG3_GEOKA/1-169                  ...........................................................................................M-KILTTQTIGLLQKIAADEELALEDGARLLAQ.A....A.IGDGRIWLYGIG.....ELDAVVTA.....ALL...GPDP..LPKAKRLEPTAT................dDWQETDRALLFARFSADPEAIRLVEQLQAHGVDAVAVAAL.VKDEPG.........LADMATVFIDSKLSRP..LV..PTE.D.G.R.RIGMPTIITASFIYYGLRVLLDEIL........................................
B7GMI2_ANOFW/7-174                  ...........................................................................................MLKILSTQLSGVFQRISAQEEEQFEDAARLLAQ.T....V.ISNGTIFIYGID.....EMEAVVAE.....ALY...GAEK..LPNVKRLDINE-.................-VTTADRVLIVSRFCTNEEAIRIAKQLQEQNIWTIGMSSI.VEETTQ........tLVDYVDVHIDLCLKQP..LV..PTE.D.G.A.RVGFPSAIAALFAYHSLALMTKDII........................................
K6DVL1_9BACI/1-172                  ...........................................................................................MLKMFATQLTGIFKKIDEKEEFSFEDGARLLAQ.A....P.VGDGSIYLFGTK.....EMRAVEYE.....ALE...GAEP..FLEAKLLSATSV................eQLSDADRVVIFTRTAGDEEAVALGRQLRERDIPFVAVSTV.MEHDTEg.......dLAELADVHIDLRLTRG..LL..PDD.M.G.N.RYGYPSSMAALFVYYGLKFTIEEML........................................
A0A023CKC5_GEOSE/1-171              ...........................................................................................M-KIFATQTIGFLQKIAAEEELALEDGARLLAQ.A....V.IGDGRILLHGVG.....EMEAVVIE.....ALY...GPDP..LPRAARLMENGRl..............rdDIDETDRILLIARFSNDNDAVRLAEQLKNEGAEIVAISAL.VKDEPS.........LADIVDVHIDSKLLKP..VV..PKE.D.G.S.RIGMPTVIAASFAYYCLLLTMDDIL........................................
A0A0B1XY56_9BACI/1-169              ...........................................................................................MSKILTTQLSGLLQRITQNEEDAIEETARLLAQ.A....A.IGEGNVYFACFG.....EMQTVELN.....ALQ...AVEP..FSKLAPWTSDT-.................SLTEADRVCIFTRSAHDEEALALAQKLNTQFIPFAAVAGE.PASTEN........pLGDLAYTYISTRIKGG..LL..PND.L.G.Q.RVVVPHALAGLFVYEAVKMAYDDML........................................
A0A0F5I5Y2_9BACI/1-169              ...........................................................................................MLKMFTTQLHGLFQRIADKESFSIEDGARLLTQ.A....I.VGEGTIYIQAFN.....EMDAVAAE.....ATS...GAEK..LTSSQTYTVNT-.................PVTESDRVLLISRFANDPEALEAAASWREADIPFVAIAGSlPKEENR.........LAELADVFIDTHLVKG..LL..PDD.T.G.G.RTGFPSSLAALYIYFALKLTIDEIL........................................
Q5HM96_STAEQ/1-168                  ...........................................................................................MSKILNTQLTGIFNRL-EKQELDIQMAAQCLIQ.A....I.GGEGHVYIKGYD.....DLKFYESF.....ILQ...SHEK..LASSLPLEDLQNf...............nDIDTTDRVLLFSPYYTS-EVESDVLQLIDLDVDLVLICNN.PKRDD-.........FPNHLIHYVNLSTPRP..IV..YTE.D.Y.D.KIIQPHPMALNYIYYDIYTQMIEMT........................................
A0A098F3K4_9BACI/1-173              ...........................................................................................MLKMFSTQLAGLFGRIHDKQEENFEDGARLLAQ.A....I.AGAGRIFIFGKG.....EMAAVGLE.....AAS...GAEP..LAGVVVWDGQER................eDFSAADRALVFARYSTDPEAVHAAQVLQNNGIPFTAVSTV.AEGEGDs......asLVDLADVHLDLMLKRG..LL..PDE.T.G.G.RFGFPAPIAALFVYYGLKFTIEEIL........................................
C2WEU2_BACCE/1-171                  ...........................................................................................MLKIFSTQLSGYFTRISQKEEMNIEDSARLLAQ.A....L.IGDGIVYLHGAR.....EMEGVVLE.....ALY...GNEP..LKQAKRLIENGNq...............aEVTPADRVLLISRFSTDEHTISIAKKLQEDGQSIVGISAV.QEGTES.........LEQFTDVHIDIKLLKG..LI..PDD.E.G.N.RYGFPSLILALFAYHGLKFTIDEII........................................
F9DRD4_9BACL/1-168                  ...........................................................................................M-KILTTQIRGLLERISGSQEEAIEETARLLAQ.A....L.VGEGRIILAAFD.....EMEAVTAT.....ALH...GAEP..LRQAVRYTGDI-.................SLTTADRVWLIVRKADHPAAVQLAKQLADQFIPFAVLAAD.SAEDSN........eLADLALTYISTGLKKG..LL..PGP.T.G.E.RIVEPHALAALFIYEAVKLSLDELL........................................
D5DWJ0_BACMQ/1-172                  ...........................................................................................MLKIFTTQLSGFFKRIEEQEEFQFEDAARILAQ.A....S.VGEGFIYIYGVE.....EMHAITLE.....AIS...SAEP..LSQAKALPLHEL................dQLTSVDRVLLVSRFSTDNKAVKIAERLKKQDIPFVSIAAV.PKEIAEp.......sLTALADAHIDTKLLKP..LI..PGE.D.G.S.RFGFPAMIVALYAYYGLTFTLKEIV........................................
D3FPQ2_BACPE/1-169                  ...........................................................................................MIPIFTTQLMGRVKAVREKEE-EFEDAARLLAQ.A....L.VGEGTIYVYGCR.....ELRGVTAE.....AEY...GTDR..DERIKPLTQDNL................sELTPADRVLLFAPFTNDGEACRMATKLHIQGVPFASVSNF.HDEQDA.........SFSLADLHIDFESDIG..LV..PDE.E.G.N.RSGYPTSIIGLYTYFCIMLTVKEIM........................................
A0A0M2PA46_9BACI/1-173              ...........................................................................................MMKIFTTQLIGHLNRIQDQEEMNIEDSARLLAQ.A....L.IGEGKLYIYGYK.....ELHGVVLE.....AMA...SSEP..LEKAEALLDENGq..............vkELSQEDRVLLFTYRSTDEEAMSIAKALSDQGIQLVGVSAL.IKNAES........gLDSITDLHIDAKLRQP..LI..PDE.D.G.E.RYGFPALMTSLYVFYALSFTIKEIL........................................
A0A0C2Y9R4_BACBA/1-169              ...........................................................................................MLKMLTTQLNGLFQRIADKEADQIEDGARLLAQ.A....A.VGEGKIYIKGFQ.....EMKAVEAE.....AAS...GAEP..LPCGCPLDSMD-.................DLAGHDRVLLVSRFAHDPEAAAAAAALRERGIPFVAAAGR.MPNEEP........sLAQMADVFIDTRLTKG..LL..PDE.N.G.G.RTGFPSSLAALYIYFALKLTIEEIL........................................
A0A060LYG8_9BACI/1-165              ...........................................................................................MDKIYTTQLIGLLKKINDTQLDELENAARLLSQ.S....I.MANGTIYVKGIA.....ELKALEYA.....TTA...SYES..LPNGEIYSNQT-.................-LSSVDRFLLFSPDASDFETTKLLKDCSEAGVPVVLMITG.ECIGN-.........-EIDADSVIELGLTKG..LT..PNE.Q.G.E.RIGHPGLIATLYMHNQLYLNTLDI-v.......................................
B9DMD9_STACT/1-168                  ...........................................................................................MANILQTQLTGIFNRI-NNQALDIQMAAQCLIQ.A....I.GGEGNVYVRGYD.....DLKFFETY.....ITQ...SHEK..LESSRLLSDLDNf...............nDLDTTDRVLLFAPFYTE-AVQHDTQALIDLDVDFVLICNK.NKEVE-.........IPDHLLHYINLNTPRP..IV..YTE.D.Y.D.KVVQPHPMALSYIYYEIYTQMIEMI........................................
A0A0B5AQ69_9BACL/35-204             ...........................................................................................MLKMFTTQLTGLFGRLQSKEEMEIENAARLLAQ.A....T.VGDGSIYIKGFG.....EMAGVAAE.....ALQ...GEEP..LEGVRELQNNIA.................GLTVADRVLLVTRRTTDPQALSFAEKLMEAEIPFAVIAGK.VKDAEG........dLEEKADSFLNTQTVRG..ML..PDE.T.G.G.RFGFPSLMAALYLYHGVKFVLDEIL........................................
Q9K6E1_BACHD/1-172                  ...........................................................................................MIQIFTTQLTGLLKQLKEKEE-SFEDGGRLLAQ.A....L.IGEGTIYIHGFH.....EMTAVQSE.....ALL...GVET..FSSVAPLVLSNGk..............iaEVTAADRVMLFTRYSDDAEAVTVAKTLADQGVEMVGISTV.KECEGT........sLTSVVDVHIDLGATLS..LV..PGE.D.G.N.RYGYPGTLLALFAYQCLYLSTLDIL........................................
E5WGS3_9BACI/1-169                  ...........................................................................................MLKMFSTQLTGLFKRLQEKEEFSIEDSARLLAQ.A....A.AGDGKIYIYGTK.....EMAAIGYE.....AVQ...SQEP..LRDAAILKSDE-.................EVSETDRVIIFSRHSDDEDAAALAKSLSEKGIPFVAVSTI.KTESSE........nLADLADVHIDLKLAKG..LL..PDE.E.G.N.RFGYPASMAALFVYYGIKFTIEEIL........................................
A0A0A8JHK3_BACSX/1-168              ...........................................................................................M-KILSTQVSGLLQRIVTNEEEAMEETARLLAQ.A....T.AGEGRVIFSAFG.....EMGAVTAT.....ALR...GVEP..FAGAVRYESDM-.................PIGSADRVWLLTRSATDPSALELARRLAEQFIPFGALAAE.KPDGDN........eLADLAYTYISTGLTKG..LL..PGE.N.G.E.RIVHPHALAALFVYEAVKLVYDEML........................................
A0A094XB60_BACAO/1-174              ...........................................................................................MIQIFTTQIQGLMKQIKDKQEEAIEDGARLLAQ.A....R.VGSSSIYVHGTK.....EMGVIEQE.....ALS...GEDH..LIHIKPLLCEEKv...............vSLDVNDRVLLASRYTTDPDAIKIAKDLKEKGIPFVAISTL.KEVEATs......egLDTLADVFIHLNVKKP..VV..PLD.D.G.T.RTGYPASLIALYTYFCLALTLKEIL........................................
Q5WB44_BACSK/1-168                  ...........................................................................................MLKIFSTQLFGLIKSINETQEEHLEDAGRLLAQ.A....I.IAQGNVYIKGFA.....EMEAIELA.....AFT...GYES..MPGAAPFPKEG-.................TLSGQDRCLLFAPSLNHKGVQAALKACEQAGIAAVVVSSR.HASSTA.........SLAPPHLFLDTGVKGG..LV..PDE.T.G.K.RIGHPGVIAGLYVYHGLKFVIHDIL........................................
A0A090J5D8_9BACI/1-170              ...........................................................................................MSKIFTTQLIGRLQKI-SEQELDIEDAARLLAQ.A....L.VGEGSIYIFGEN.....DLRSVFLE.....AKY...GQEP..LQRVQEWTGDTF................eQLSTADRVLIFSRNIANEQVVVLAKKLRSLQVPFVVVGSI.SVKDVN........pVENLADVCINLHIDTG..LV..PDE.R.G.G.RTMYPHAIAALYVYHSLKFRIDEIM........................................
Q81JW2_BACAN/1-171                  ...........................................................................................MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQ.A....L.VGEGFIYLHGTN.....EMDGIVAE.....ALF...GAEP..MKQAKRLFENGKe...............vEVTSADRVLLISRFSTDEEVVAIAKKLQADGHSIVGISAI.QEGTES.........LEQYTDVHIDTKLLKG..LI..PDD.E.G.N.RYGFPSLMIALFAYHGIKFTIDEML........................................
I8IWI6_9BACI/1-169                  ...........................................................................................MLKIFSTQLHGIFQTIAEKNEFAIEDSARMMAQ.T....I.LSHGHIYVYGRN.....ELASLSAH.....ALY...SNEA..LPGVAMLPDDLT.................TITATDTVLIAAPTKEDEEANERLRAIKATSNAYVIFLAA.SSNRAL.........EHTGVDSFIQLFATKG..LV..PNE.A.G.E.RVGLPTSMAALYAYHALHLTTQEIL........................................
A7GV87_BACCN/1-171                  ...........................................................................................MLKIFSTQLSGYFTRISQKEEMNIEDSARLLAQ.A....L.VGDGIIYLHGKN.....EMEGVVAE.....ALY...GAEP..LPRAKHLIEHGKq...............aEVTSADRVLLISRFSTDEEVVSIAKKLQEEGHSIVGISAI.QEGAES.........LEHFTDVHIDTRLLKG..LI..PND.E.G.N.RYGFPSLILSLFAYHGLKFTIDEMI........................................
A0A077J9L1_9BACI/1-171              ...........................................................................................MLKMFTTQLTGLFKRIAEKEEFAFEDGARLLAQ.A....P.VGDGAIYIYGTK.....EMKAIELE.....ALE...GEEP..FQWAKGLTTSAT................eKLDHADRVIIFSRTSGDKEAVKLAKELKEKGIPFVAVSSV.VDSTVS........gLAEMADIHIDLRLTKG..LL..PDE.Y.G.N.RFGYPSSMAALFVYYGLKFTIEEIL........................................
E6MD45_STALU/1-168                  ...........................................................................................MSKILNTQLTGIFNRI-EKQAMEIQMAAQCIVQ.A....I.GGEGFVYIKGYE.....DLAFFEPF.....ILQ...SQER..LRSSRQLSTLNSf...............dDLDTTDRVFLFSPFYNE-AVAQDISALLQRDIDIVLVSNR.PKSDD-.........FPEHLLHFINLSTPRP..IV..YTE.D.Y.D.KIVQPHSMAFNYIYYDIYTQMVEMT........................................
A0A0N0EBF9_9BACI/1-178              ...........................................................................................MLKIFTTQLQGVFNRIGSSEEFAFEDAARLLAQ.A....A.VGDGRIYVHGVK.....EMKAVEAE.....ATT...GAEP..LMSATLLSNLDRy...............hDLTDTDRALIVSRFSTDEEAISTAKALKELGIEIVGISTV.MEPSLEtve..gaetLETLSDVHIDLKLKKP..LI..PGD.D.G.E.RFGFPSSMVALYVYHGLAFTLKEIL........................................
H0DGG7_9STAP/1-168                  ...........................................................................................MSKILNTQINGVFNRL-EKQELDIQMAAQCLIQ.A....I.GGEGHVYVKGYD.....DLKFYETF.....VTS...SSER..LESSKLLDELANl...............dELDTTDRVFLFGPYYSE-EMAEDVSKLIDIDADFVVICNK.PKETE-.........FPDHLFHFVNLSTPRP..IV..YTE.D.Y.D.KVVTPHPIAFNYVYYEIYTQMVEMI........................................
C5D9P8_GEOSW/1-172                  ...........................................................................................M-KIFTTQMIGYLKKIAEEEEMAFEDGARLLAQ.A....I.IGDGRILLHGFH.....EMEAVVIE.....ALC...GQDK..LPKAVRLMENGHl..............rnDIDETDRVLLIARFSNDKDAIRLAERLKEQGLEIAAISAV.VKDEQP........sLVDIVDVHIDSKLLKP..IV..PKD.D.G.S.RIGFPTVITASFAYYCLLLTIYDIL........................................
D6Y0U7_BACIE/1-170                  ...........................................................................................M-KMFFTQLQGLAKDI-EDQEDIIEDAARLLAM.S....I.VSDGSVYWYSEG.....EMDGIVTQ.....AMT...GDDG..IPDSKRWSEAH-.................SLSEQDTVVICSKWRDSVSASDVAKRAEEAGATVIGITSA.MSVSKDk......hdWTTGAELLLVNGVSKG..LI..PSE.D.G.EtRIGTPHLLAGLHVYYTLFFVLRDIL........................................
A0A098EHY2_9BACL/1-158              ...........................................................................................M-KMLATQTAGLLQRL-AKQEEAVEDTARVLAQ.A....A.VGEGNIFLAAFG.....EMKAVVET.....ALN...GVEP..LASAIDWKPDS-.................ILTSADRVWILAPNDEG---DELAGRLNDAGIPFAMVTGV.ARELE-.........----ADAFISLGISKG..LI..PTD.D.G.G.RTLVPYAMGALFIYHAVKLIIDEML........................................
F2F763_SOLSS/1-171                  ...........................................................................................MSKILTTQLTGLLQRIQQTEEESIEETARLLAQ.A....A.IGQGTIYFAAFG.....EMEAVAVN.....AEL...GAGT..FTKFARYTEEV-.................ELMPADRVIIFTRHATDEQALKLAQQLHAEFIPFAAVASE.VASDDN........pLSDLAYTYISLKVRGG..ILphPTK.L.G.E.RIVFPHLIAALYIYEAIKMEFDEML........................................
Q2FWD2_STAA8/1-168                  ...........................................................................................MSKILNTQLIGIFNRL-EKQSLEIQMAAQCLIQ.A....I.GGEGYVYVKGYD.....DLQFFESF.....ILH...SDER..LKSSRKLDAIKDf...............kEIDSTDRVLLFAPFYND-QVALDIQKLIDLDIDVVLISNK.PKTDD-.........FPDHLVHFIDLSTPRP..IV..YTE.D.Y.D.KIVQPHAMALNYVYYDIYTQMIEMT........................................
A0A0M8PY35_9BACI/1-169              ...........................................................................................MSKILTTQLSGLLQRITQNEEEAIEETARLLAQ.A....G.IGEGNVYFACFG.....EMQVVELN.....ACQ...AVER..FAKLVPWTKDT-.................VITEADRVCIFTRGAHDEEALALAHQLNNHFIPFAAVASE.VADSEN........pLADLAYTYISTRIRGG..LL..PND.L.G.E.RIVVPHSIAALFVYEAVKIAYDEML........................................
A6CQ30_9BACI/7-176                  ..........................................................................................l-IKMFTTQLSGLFNRIADKEEFSIEDGARLLAQ.A....T.VGEGSIYIKGFA.....EMESVTLE.....ALS...GHEP..LPSAKALTNAD-.................ALTVADRVLLVSRFSTDEEAVALAKQLSDQGVAFTAISGA.VSGEGE........sLTDLADIHIDTKLIKG..ML..PGE.ElG.E.RVGFPSSMAALYIYYLIKFSLEEML........................................
A8FIE4_BACP2/1-172                  ...........................................................................................MLKIFTTQLSGIFSRIGEKQAEAIEDGARLLAQ.A....V.VSGHGVYFHGKN.....ELAAVALE.....ATE...SKEP..FPCAKVLPLDQTe..............rsLLHPSDRVLLFYSEPEDEEIESLVKELHAQGTPVVGVGPA.QKEPSM.........IEEHCDVHIDFQLKKP..LV..PAD.D.G.T.RFGYPALMTCLYVYHALSFTVKEIV........................................
E8SDZ5_STAPH/1-168                  ...........................................................................................MSKMLTTQLTGIFNRL-DQQELDIQMAAQSLIQ.A....M.GGEGHVYIKGYG.....DLKCFESY.....ILT...SFEK..LHSSLALDDYPSf...............dVLDTTDRVLLFGAEYSE-EMARDLEQLIADDRDVVVITNK.PKEVE-.........LPDHLMHFINLSTPRP..IV..YTE.D.Y.D.KVVQPHLMALNYVYYEIYTQMVEMM........................................
C2X4D0_BACCE/1-171                  ...........................................................................................MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQ.A....L.VGDGFIYLHGTN.....EMDGVVAE.....ALF...GAEP..MQQAKRLFENDKe...............aEVTSADRVLLISRFSTDEEAVNIAKKLQEEGHSIVGISAI.QEGIES.........LEQYTDVHIDTKLLKG..LI..PDD.E.G.N.RYGFPSLMIALFAYHGLKFTIDEML........................................
A0A0H4KPH8_9BACI/1-172              ...........................................................................................MMKIFTTQLNGYFNRISEKEELNIEDGARILAQ.G....L.IGDGKLFVHGFQ.....EMEALAIE.....ATK...GADA..LNAELLLSNENL................eNITSVDRVLVCSRYAHDQEAIELAKAISEKNIPFVTIGAL.DPKQEGe.......tAANYSDVHIDTKLLKP..LI..PGE.D.G.E.RFGFPSTMVGLYAYYAVLFTIKEMM........................................
B1YEL3_EXIS2/1-165                  ...........................................................................................MLKILATQFNGKLQTL-TKQEDELFDVVRLLAQ.A....L.VGQGKVYLDAYG.....EFEGLYPM.....LSD...GPDQ..MKRVTKIKDHK-.................TLHAVDRVLIFTPDTERSDLLASLARYDAWHTPYSIITLG.DVTET-.........-LERSIAPLALKFDKG..LL..PAE.D.G.S.RHGLPSLALGAFLLTHILTQLQEMT........................................
#=GR B1YEL3_EXIS2/1-165       SS    ...........................................................................................HHHHHHHHHHHHHHHH-HCCHHHHHHHHHHHHH.H....H.HTT--EEEEE-G.....GGGGGHHH.....HHC...STT-..-TTEEE--TT--.................---TT-EEEEEES-S--HHHHHHHHHHHHHT--EEEEESS.---TT-.........-GGGSSS-EE----S-..SE..E-T.T.S.-.EE---HHHHHHHHHHHHHHHHHHHH........................................
Q65DT8_BACLD/1-172                  ...........................................................................................MLKIFTTQLTGIFNRIQEGEAQSIEDGARLLAQ.A....V.ISDHSVYVYGKN.....ELEGILKE.....AMY...SSEP..FPSVKPLQKDEEn..............wpDFEMTDKVLMFCAGSADDEELKMAEKLYEKGIGLVVVSPS.GKDGVP.........IASFADVHIDSKLRMP..LL..PDE.D.G.T.RYGFPSLMVSLYIYHALSFTLKEIL........................................
A0A0F7HLF8_9STAP/1-166              ...........................................................................................MDKILQTQLVNIYNHI-DAQSEEIEMAARLLSQ.A....V.HSEGGIYIKTFH.....DIAGMENY.....LLE...GTLS..LPKVKRLDAIS-.................EVGSPDRVLVSADMFDE-EVKAFVEALETADIEFVLVSNF.NKHESE.........KMDRIHHYIDLSSPRP..LI..PTP.N.F.D.KIVNPYMSAFLYLYNHLYVLIDEMT........................................
I3EBM8_BACMT/1-169                  ...........................................................................................MLKMFSTQLTGLFNRIQDKEEFSIEDGARLLAQ.A....A.VGDGSIYICGLK.....EMAAVEAE.....ATE...GAEP..LVSAKKWTALD-.................EIQEADRVLLLSRYSRDKEAVEIARALTEKNIPFVAVSTA.VENNSD........dLTSLADIHIDLRLVKG..LL..PNE.E.G.G.RFGYPSSIAALFVYFALKLTIDEII........................................
N0B1J3_9BACI/1-177                  ...........................................................................................MLKMFSTQLAGLFKRIQEQNEFSFEDGARLLAQsA....A.SSDGAIYICGFG.....EMAAVEAE.....ACC...GAEP..LSFAKKWDGVQ-.................EVTEADRVVMFSRFSNDCDAVALAQSLVAQGIPFVAVSTD.VTAAGLtdqs.dfvdLTKLADVFIDLKLSKG..LL..PDE.S.G.N.RVGYPAAMAGLYVFHGLKFTLEEIL........................................
X2GPC9_9BACI/1-169                  ...........................................................................................MSKILTTQLSGLLQRITQNEEEAIEETARLLAQ.A....A.IGEGNVYFACFG.....EMQVVELN.....ALQ...GVER..FSKLLPWTEHT-.................VVSKADRICIFTRSAHDQEALALAQKLSAQFIPFAAVASE.VANNEN........pLADLAYTYISTRMRGG..LM..PND.L.G.E.RIVVPHAIAALFIYEAVKVIYDEML........................................
U5LIT8_9BACI/1-172                  ...........................................................................................MLKMFSTQLTGIFKKLMEKEEFSIEDAARLLAQ.A....P.AGEGRIQIYATR.....EMKAAALE.....ATE...GAEP..LASAAHWTDAHSe...............nDIADTDRFLIISRHSNDGQAVALAKALSEKMIPFTAISTA.VEGEGP........sLAELADVHIDLKLTKG..LL..PDE.E.G.N.RFGYPSAIAALFVYHGLKFTIDEIL........................................
#=GC SS_cons                        ...........................................................................................HHHHHHHHHHHHHHHH-HCCHHHHHHHHHHHHH.H....H.HTT--EEEEE-G.....GGGGGHHH.....HHC...STT-..-TTEEE--TT--.................---TT-EEEEEES-S--HHHHHHHHHHHHHT--EEEEESS.---TT-.........-GGGSSS-EE----S-..SE..E-T.T.S.-.EE---HHHHHHHHHHHHHHHHHHHH........................................
#=GC seq_cons                       ...........................................................................................MhKIFoTQLsGlapRIt-ccE.sIEDuARLLAQ.A....h.lG-GpIYltGhs.....EMcuVthp.....Ahp...GsEs..Ltpuptlssps..................plossDRVLlhoRhusDt-AlplAcpLp-pslshVulush.scssss.........LsshsDlaIDhplp+u..Ll..PsE.c.G.s.RhGaPsshAALalYaulphslcEhL........................................
//
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