GenomeNet

Database: Pfam
Entry: DUF2529
LinkDB: DUF2529
Original site: DUF2529 
#=GF ID   DUF2529
#=GF AC   PF10740.6
#=GF DE   Domain of unknown function (DUF2529)
#=GF AU   Mistry J, Coggill P
#=GF SE   PRODOM_PD099482
#=GF GA   22.30 22.30;
#=GF TC   22.30 22.40;
#=GF NC   22.20 22.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019676;
#=GF CC   This domain is conserved in the Bacillales. The function is not
#=GF CC   known, but given this domains relationship to the SIS domain it
#=GF CC   may carry out a sugar isomerase reaction. Several members are
#=GF CC   annotated as being YWJG, a protein expressed downstream of pyrG,
#=GF CC   a gene encoding for cytidine triphosphate synthetase.
#=GF SQ   35
#=GS A0A0A8JHK3_BACSX/1-168   AC A0A0A8JHK3.1
#=GS Q5WB44_BACSK/1-168       AC Q5WB44.1
#=GS B9E8H0_MACCJ/1-161       AC B9E8H0.1
#=GS Q81JW2_BACAN/1-171       AC Q81JW2.1
#=GS E6TXE0_BACCJ/1-171       AC E6TXE0.1
#=GS A7GV87_BACCN/1-171       AC A7GV87.1
#=GS A0A077J9L1_9BACI/1-171   AC A0A077J9L1.1
#=GS A0A0B4RE02_9BACL/1-159   AC A0A0B4RE02.1
#=GS Q814T3_BACCR/1-171       AC Q814T3.1
#=GS YWJG_BACSU/1-169         AC P06629.1
#=GS Q5KUG3_GEOKA/1-169       AC Q5KUG3.1
#=GS B7GMI2_ANOFW/7-174       AC B7GMI2.1
#=GS C5D9P8_GEOSW/1-172       AC C5D9P8.1
#=GS D6Y0U7_BACIE/1-170       AC D6Y0U7.1
#=GS F2F763_SOLSS/1-171       AC F2F763.1
#=GS Q5HM96_STAEQ/1-168       AC Q5HM96.1
#=GS A0A0F5I5Y2_9BACI/1-169   AC A0A0F5I5Y2.1
#=GS Q2FWD2_STAA8/1-168       AC Q2FWD2.1
#=GS D5DM78_BACMD/1-172       AC D5DM78.1
#=GS A8FIE4_BACP2/1-172       AC A8FIE4.1
#=GS B1I054_LYSSC/7-175       AC B1I054.1
#=GS E8SDZ5_STAPH/1-168       AC E8SDZ5.1
#=GS C2X4D0_BACCE/1-171       AC C2X4D0.1
#=GS D3FPQ2_BACPE/1-169       AC D3FPQ2.1
#=GS B1YEL3_EXIS2/1-165       AC B1YEL3.1
#=GS B1YEL3_EXIS2/1-165       DR PDB; 3JX9 A; 1-165;
#=GS B1YEL3_EXIS2/1-165       DR PDB; 3JX9 B; 1-165;
#=GS A0A0C2Y9R4_BACBA/1-169   AC A0A0C2Y9R4.1
#=GS Q65DT8_BACLD/1-172       AC Q65DT8.1
#=GS I3EBM8_BACMT/1-169       AC I3EBM8.1
#=GS A0A060LYG8_9BACI/1-165   AC A0A060LYG8.1
#=GS N0B1J3_9BACI/1-177       AC N0B1J3.1
#=GS A0A0B5AQ69_9BACL/35-204  AC A0A0B5AQ69.1
#=GS B9DMD9_STACT/1-168       AC B9DMD9.1
#=GS Q9K6E1_BACHD/1-172       AC Q9K6E1.1
#=GS X2GPC9_9BACI/1-169       AC X2GPC9.1
#=GS U5LIT8_9BACI/1-172       AC U5LIT8.1
A0A0A8JHK3_BACSX/1-168              .............................................................M-KILSTQVSGLLQRIVTNEEEAMEETARLLAQ.A....TAGEGRVIFSAFG.....EMGAVTAT.....ALRGVEPFAGAVRYESDM-.......PIGSADRVWLLTRSATDPSALELARRLAEQFIPFGALAAE.KPDGDN.......eLADLAYTYISTGLTKG.LL..PGEN.G.E.RIVHPHALAALFVYEAVKLVYDEML..........................................
Q5WB44_BACSK/1-168                  .............................................................MLKIFSTQLFGLIKSINETQEEHLEDAGRLLAQ.A....IIAQGNVYIKGFA.....EMEAIELA.....AFTGYESMPGAAPFPKEG-.......TLSGQDRCLLFAPSLNHKGVQAALKACEQAGIAAVVVSSR.HASSTA........SLAPPHLFLDTGVKGG.LV..PDET.G.K.RIGHPGVIAGLYVYHGLKFVIHDIL..........................................
B9E8H0_MACCJ/1-161                  .............................................................MFKIFNTQLNGIFKKI-EAQEVEIDIAARLLAQ.A....VVGQGKIYVKGFG.....DLKHFEDF.....AVESKEKLFDTEKFITES-.......LIDQTDRILVMSDSYDE-DCHEFITMLKEKDIDFVLVCNK.DDRID-........----VMNFIDLSTPRA.LV..PTEN.F.S.RIITPHMMAMNFIYYGIYNVMYEML..........................................
Q81JW2_BACAN/1-171                  .............................................................MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQ.A....LVGEGFIYLHGTN.....EMDGIVAE.....ALFGAEPMKQAKRLFENGKe.....vEVTSADRVLLISRFSTDEEVVAIAKKLQADGHSIVGISAI.QEGTES........LEQYTDVHIDTKLLKG.LI..PDDE.G.N.RYGFPSLMIALFAYHGIKFTIDEML..........................................
E6TXE0_BACCJ/1-171                  .............................................................M-KIFQTQLQGLIRKI-DDYEESFEEATRYIAQ.S....MISDGKVYIFGDM.....EMVGIIPQ.....ALNGVDRLPGCLEASETS-.......VFTPLDTVLIFSPNKGSKAAAKVADNARGAGGNVIGVFSE.TTENDGdm...qidWTSQCTVSFSTSISHG.LM..PTES.G.D.RIGVPHLLVALHFYYALYFTTMEF-m.........................................
A7GV87_BACCN/1-171                  .............................................................MLKIFSTQLSGYFTRISQKEEMNIEDSARLLAQ.A....LVGDGIIYLHGKN.....EMEGVVAE.....ALYGAEPLPRAKHLIEHGKq.....aEVTSADRVLLISRFSTDEEVVSIAKKLQEEGHSIVGISAI.QEGAES........LEHFTDVHIDTRLLKG.LI..PNDE.G.N.RYGFPSLILSLFAYHGLKFTIDEMI..........................................
A0A077J9L1_9BACI/1-171              .............................................................MLKMFTTQLTGLFKRIAEKEEFAFEDGARLLAQ.A....PVGDGAIYIYGTK.....EMKAIELE.....ALEGEEPFQWAKGLTTSAT......eKLDHADRVIIFSRTSGDKEAVKLAKELKEKGIPFVAVSSV.VDSTVS.......gLAEMADIHIDLRLTKG.LL..PDEY.G.N.RFGYPSSMAALFVYYGLKFTIEEIL..........................................
A0A0B4RE02_9BACL/1-159              ............................................................m--DLFTTQLTRLIERLSEEH-EAIESIAAVLAQ.A....AIAEGTIFTAAFG.....EMKAVTAV.....ALHSDNPLQNAAEWSSAS-.......IVTDIDRVFILATNNEG---AELAGRLSDAGIPFAYVAPP.SNDSE-........---LADAFLALISEET.SL..IQDG.N.N.ALLVPHALAGLYVYYAVKLRIDKL-l.........................................
Q814T3_BACCR/1-171                  .............................................................MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQ.A....LVGDGFIYLHGTN.....EMEGVVAE.....ALFGAEPMKQAKRLFENGKe.....aEVTSADRVLLISRFSTDEAVVEIAKKLQEEGHSIVGISAL.QEGTES........LERYTDVHIDTKLLKG.LI..PDDE.G.N.RYGFPSLIVALFAYHGIKFTIDEML..........................................
YWJG_BACSU/1-169                    .............................................................MLKIFTTQLTGIFSRIQDKESDAIEDGARLLAQ.A....VISGHSIYLYGAN.....ELQGVFYE.....ATESKEPFPSVKAFPENAE.......EVTESDRVLMFCSGTGTAEEQELAKELYEKGAGVVCVSPA.AKDSAG........IEQYCDVHIDSKLKMP.LV..PDED.G.T.RYGFPSLMTALYVYHALSFTLKEIL..........................................
Q5KUG3_GEOKA/1-169                  .............................................................M-KILTTQTIGLLQKIAADEELALEDGARLLAQ.A....AIGDGRIWLYGIG.....ELDAVVTA.....ALLGPDPLPKAKRLEPTAT......dDWQETDRALLFARFSADPEAIRLVEQLQAHGVDAVAVAAL.VKDEPG........LADMATVFIDSKLSRP.LV..PTED.G.R.RIGMPTIITASFIYYGLRVLLDEIL..........................................
B7GMI2_ANOFW/7-174                  .............................................................MLKILSTQLSGVFQRISAQEEEQFEDAARLLAQ.T....VISNGTIFIYGID.....EMEAVVAE.....ALYGAEKLPNVKRLDINE-.......-VTTADRVLIVSRFCTNEEAIRIAKQLQEQNIWTIGMSSI.VEETTQ.......tLVDYVDVHIDLCLKQP.LV..PTED.G.A.RVGFPSAIAALFAYHSLALMTKDII..........................................
C5D9P8_GEOSW/1-172                  .............................................................M-KIFTTQMIGYLKKIAEEEEMAFEDGARLLAQ.A....IIGDGRILLHGFH.....EMEAVVIE.....ALCGQDKLPKAVRLMENGHl....rnDIDETDRVLLIARFSNDKDAIRLAERLKEQGLEIAAISAV.VKDEQP.......sLVDIVDVHIDSKLLKP.IV..PKDD.G.S.RIGFPTVITASFAYYCLLLTIYDIL..........................................
D6Y0U7_BACIE/1-170                  .............................................................M-KMFFTQLQGLAKDI-EDQEDIIEDAARLLAM.S....IVSDGSVYWYSEG.....EMDGIVTQ.....AMTGDDGIPDSKRWSEAH-.......SLSEQDTVVICSKWRDSVSASDVAKRAEEAGATVIGITSA.MSVSKDk.....hdWTTGAELLLVNGVSKG.LI..PSED.G.EtRIGTPHLLAGLHVYYTLFFVLRDIL..........................................
F2F763_SOLSS/1-171                  .............................................................MSKILTTQLTGLLQRIQQTEEESIEETARLLAQ.A....AIGQGTIYFAAFG.....EMEAVAVN.....AELGAGTFTKFARYTEEV-.......ELMPADRVIIFTRHATDEQALKLAQQLHAEFIPFAAVASE.VASDDN.......pLSDLAYTYISLKVRGG.ILphPTKL.G.E.RIVFPHLIAALYIYEAIKMEFDEML..........................................
Q5HM96_STAEQ/1-168                  .............................................................MSKILNTQLTGIFNRL-EKQELDIQMAAQCLIQ.A....IGGEGHVYIKGYD.....DLKFYESF.....ILQSHEKLASSLPLEDLQNf.....nDIDTTDRVLLFSPYYTS-EVESDVLQLIDLDVDLVLICNN.PKRDD-........FPNHLIHYVNLSTPRP.IV..YTED.Y.D.KIIQPHPMALNYIYYDIYTQMIEMT..........................................
A0A0F5I5Y2_9BACI/1-169              .............................................................MLKMFTTQLHGLFQRIADKESFSIEDGARLLTQ.A....IVGEGTIYIQAFN.....EMDAVAAE.....ATSGAEKLTSSQTYTVNT-.......PVTESDRVLLISRFANDPEALEAAASWREADIPFVAIAGSlPKEENR........LAELADVFIDTHLVKG.LL..PDDT.G.G.RTGFPSSLAALYIYFALKLTIDEIL..........................................
Q2FWD2_STAA8/1-168                  .............................................................MSKILNTQLIGIFNRL-EKQSLEIQMAAQCLIQ.A....IGGEGYVYVKGYD.....DLQFFESF.....ILHSDERLKSSRKLDAIKDf.....kEIDSTDRVLLFAPFYND-QVALDIQKLIDLDIDVVLISNK.PKTDD-........FPDHLVHFIDLSTPRP.IV..YTED.Y.D.KIVQPHAMALNYVYYDIYTQMIEMT..........................................
D5DM78_BACMD/1-172                  .............................................................MLKIFTTQLSGFFKRIEEQEEFQFEDAARILAQ.A....SVGEGFIYIYGVE.....EMHAITLE.....ALSSAEPLSQAKALPLHEL......dQLTSVDRVLLVSRFSTDNKAMEIAERLKKRDIPFVSIAAV.PKEIAEp......sLTALADAHIDTKLLKP.LI..PGED.G.S.RFGYPAMIVALYAYYGLTFTLKEIV..........................................
A8FIE4_BACP2/1-172                  .............................................................MLKIFTTQLSGIFSRIGEKQAEAIEDGARLLAQ.A....VVSGHGVYFHGKN.....ELAAVALE.....ATESKEPFPCAKVLPLDQTe....rsLLHPSDRVLLFYSEPEDEEIESLVKELHAQGTPVVGVGPA.QKEPSM........IEEHCDVHIDFQLKKP.LV..PADD.G.T.RFGYPALMTCLYVYHALSFTVKEIV..........................................
B1I054_LYSSC/7-175                  .............................................................MSKILTTQVSGLLQRITQNEEDAIEETARLLAQ.A....AIGEGNVYFACFG.....EMQTVELN.....ALQAVEPFSKLAPWTSDT-.......NLTEADRVCIFTRSAHDEEALALAQKLNTQFIPFAAVASE.PASAEN.......pLMDLAYTYVSTRIKGG.LL..PNDL.G.Q.RIVVPHALAGLFVYEAVKMAYDDML..........................................
E8SDZ5_STAPH/1-168                  .............................................................MSKMLTTQLTGIFNRL-DQQELDIQMAAQSLIQ.A....MGGEGHVYIKGYG.....DLKCFESY.....ILTSFEKLHSSLALDDYPSf.....dVLDTTDRVLLFGAEYSE-EMARDLEQLIADDRDVVVITNK.PKEVE-........LPDHLMHFINLSTPRP.IV..YTED.Y.D.KVVQPHLMALNYVYYEIYTQMVEMM..........................................
C2X4D0_BACCE/1-171                  .............................................................MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQ.A....LVGDGFIYLHGTN.....EMDGVVAE.....ALFGAEPMQQAKRLFENDKe.....aEVTSADRVLLISRFSTDEEAVNIAKKLQEEGHSIVGISAI.QEGIES........LEQYTDVHIDTKLLKG.LI..PDDE.G.N.RYGFPSLMIALFAYHGLKFTIDEML..........................................
D3FPQ2_BACPE/1-169                  .............................................................MIPIFTTQLMGRVKAVREKEE-EFEDAARLLAQ.A....LVGEGTIYVYGCR.....ELRGVTAE.....AEYGTDRDERIKPLTQDNL......sELTPADRVLLFAPFTNDGEACRMATKLHIQGVPFASVSNF.HDEQDA........SFSLADLHIDFESDIG.LV..PDEE.G.N.RSGYPTSIIGLYTYFCIMLTVKEIM..........................................
B1YEL3_EXIS2/1-165                  .............................................................MLKILATQFNGKLQTL-TKQEDELFDVVRLLAQ.A....LVGQGKVYLDAYG.....EFEGLYPM.....LSDGPDQMKRVTKIKDHK-.......TLHAVDRVLIFTPDTERSDLLASLARYDAWHTPYSIITLG.DVTET-........-LERSIAPLALKFDKG.LL..PAED.G.S.RHGLPSLALGAFLLTHILTQLQEMT..........................................
#=GR B1YEL3_EXIS2/1-165       SS    .............................................................-TTEEE--TT----TT-EEEEEES-S--HHHHH.H....HHT--EEEEESS-.....GGSSS-EE.....-SEE-TTS-EE---HHHH-.......HHHHHHHHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXX-........-XXXXXXXXXXXXXXX.XX..XXXX.X.X.XXXXXXXXXXXXXXXXXXXXXXXXX..........................................
A0A0C2Y9R4_BACBA/1-169              .............................................................MLKMLTTQLNGLFQRIADKEADQIEDGARLLAQ.A....AVGEGKIYIKGFQ.....EMKAVEAE.....AASGAEPLPCGCPLDSMD-.......DLAGHDRVLLVSRFAHDPEAAAAAAALRERGIPFVAAAGR.MPNEEP.......sLAQMADVFIDTRLTKG.LL..PDEN.G.G.RTGFPSSLAALYIYFALKLTIEEIL..........................................
Q65DT8_BACLD/1-172                  .............................................................MLKIFTTQLTGIFNRIQEGEAQSIEDGARLLAQ.A....VISDHSVYVYGKN.....ELEGILKE.....AMYSSEPFPSVKPLQKDEEn....wpDFEMTDKVLMFCAGSADDEELKMAEKLYEKGIGLVVVSPS.GKDGVP........IASFADVHIDSKLRMP.LL..PDED.G.T.RYGFPSLMVSLYIYHALSFTLKEIL..........................................
I3EBM8_BACMT/1-169                  .............................................................MLKMFSTQLTGLFNRIQDKEEFSIEDGARLLAQ.A....AVGDGSIYICGLK.....EMAAVEAE.....ATEGAEPLVSAKKWTALD-.......EIQEADRVLLLSRYSRDKEAVEIARALTEKNIPFVAVSTA.VENNSD.......dLTSLADIHIDLRLVKG.LL..PNEE.G.G.RFGYPSSIAALFVYFALKLTIDEII..........................................
A0A060LYG8_9BACI/1-165              .............................................................MDKIYTTQLIGLLKKINDTQLDELENAARLLSQ.S....IMANGTIYVKGIA.....ELKALEYA.....TTASYESLPNGEIYSNQT-.......-LSSVDRFLLFSPDASDFETTKLLKDCSEAGVPVVLMITG.ECIGN-........-EIDADSVIELGLTKG.LT..PNEQ.G.E.RIGHPGLIATLYMHNQLYLNTLDIV..........................................
N0B1J3_9BACI/1-177                  .............................................................MLKMFSTQLAGLFKRIQEQNEFSFEDGARLLAQsA....ASSDGAIYICGFG.....EMAAVEAE.....ACCGAEPLSFAKKWDGVQ-.......EVTEADRVVMFSRFSNDCDAVALAQSLVAQGIPFVAVSTD.VTAAGLtdqsdfvdLTKLADVFIDLKLSKG.LL..PDES.G.N.RVGYPAAMAGLYVFHGLKFTLEEIL..........................................
A0A0B5AQ69_9BACL/35-204             .............................................................MLKMFTTQLTGLFGRLQSKEEMEIENAARLLAQ.A....TVGDGSIYIKGFG.....EMAGVAAE.....ALQGEEPLEGVRELQNNIA.......GLTVADRVLLVTRRTTDPQALSFAEKLMEAEIPFAVIAGK.VKDAEG.......dLEEKADSFLNTQTVRG.ML..PDET.G.G.RFGFPSLMAALYLYHGVKFVLDEIL..........................................
B9DMD9_STACT/1-168                  .............................................................MANILQTQLTGIFNRI-NNQALDIQMAAQCLIQ.A....IGGEGNVYVRGYD.....DLKFFETY.....ITQSHEKLESSRLLSDLDNf.....nDLDTTDRVLLFAPFYTE-AVQHDTQALIDLDVDFVLICNK.NKEVE-........IPDHLLHYINLNTPRP.IV..YTED.Y.D.KVVQPHPMALSYIYYEIYTQMIEMI..........................................
Q9K6E1_BACHD/1-172                  .............................................................MIQIFTTQLTGLLKQLKEKEE-SFEDGGRLLAQ.A....LIGEGTIYIHGFH.....EMTAVQSE.....ALLGVETFSSVAPLVLSNGk....iaEVTAADRVMLFTRYSDDAEAVTVAKTLADQGVEMVGISTV.KECEGT.......sLTSVVDVHIDLGATLS.LV..PGED.G.N.RYGYPGTLLALFAYQCLYLSTLDIL..........................................
X2GPC9_9BACI/1-169                  .............................................................MSKILTTQLSGLLQRITQNEEEAIEETARLLAQ.A....AIGEGNVYFACFG.....EMQVVELN.....ALQGVERFSKLLPWTEHT-.......VVSKADRICIFTRSAHDQEALALAQKLSAQFIPFAAVASE.VANNEN.......pLADLAYTYISTRMRGG.LM..PNDL.G.E.RIVVPHAIAALFIYEAVKVIYDEML..........................................
U5LIT8_9BACI/1-172                  .............................................................MLKMFSTQLTGIFKKLMEKEEFSIEDAARLLAQ.A....PAGEGRIQIYATR.....EMKAAALE.....ATEGAEPLASAAHWTDAHSe.....nDIADTDRFLIISRHSNDGQAVALAKALSEKMIPFTAISTA.VEGEGP.......sLAELADVHIDLKLTKG.LL..PDEE.G.N.RFGYPSAIAALFVYHGLKFTIDEIL..........................................
#=GC SS_cons                        .............................................................-TTEEE--TT----TT-EEEEEES-S--HHHHH.H....HHT--EEEEESS-.....GGSSS-EE.....-SEE-TTS-EE---HHHH-.......HHHHHHHHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXX-........-XXXXXXXXXXXXXXX.XX..XXXX.X.X.XXXXXXXXXXXXXXXXXXXXXXXXX..........................................
#=GC seq_cons                       .............................................................MhKIFoTQLoGlFpRIt-cEE.sIEDuARLLAQ.A....hlG-GpIYlpGhs.....EMcultsp.....AhpGsEshssupthspss........plsssDRVLLho+hssDt-shplAcpLp-pslshVulust.scssss........LsphsDlaIDhplp+G.Ll..PsE-.G.s.RhGaPshlAuLalYaulphslcEhL..........................................
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